1734:
Ogurusu T, Yanagi K, Watanabe M, Fukaya M, Shingai R (1999). "Localization of GABA receptor rho 2 and rho 3 subunits in rat brain and functional expression of homo-oligomeric rho 3 receptors and hetero-oligomeric rho 2 rho 3 receptors".
633:
of the neuron, thus hyperpolarizes it, making it more difficult for these cells to conduct electrical impulses in the form of an action potential. Following stimulation by GABA, the chloride current produced by
1984:
Hinton T, Chebib M, Johnston GA (January 2008). "Enantioselective actions of 4-amino-3-hydroxybutanoic acid and (3-amino-2-hydroxypropyl)methylphosphinic acid at recombinant GABA(C) receptors".
1419:"gamma-Aminobutyric acid A or C receptor? gamma-Aminobutyric acid rho 1 receptor RNA induces bicuculline-, barbiturate-, and benzodiazepine-insensitive gamma-aminobutyric acid responses in
586:
1644:"International Union of Pharmacology. LXX. Subtypes of gamma-aminobutyric acid(A) receptors: classification on the basis of subunit composition, pharmacology, and function. Update"
4329:
910:
2085:
4123:
855:
2845:
4732:
3775:
3735:
2183:
1374:
Wegelius K, Pasternack M, Hiltunen JO, Rivera C, Kaila K, Saarma M, Reeben M (January 1998). "Distribution of GABA receptor rho subunit transcripts in the rat brain".
1974:
Morris KD, Moorefield CN, Amin J. Differential modulation of the gamma-aminobutyric acid type C receptor by neuroactive steroids. Mol
Pharmacol. 1999;56(4):752‐759
1147:
Drew CA, Johnston GA, Weatherby RP (December 1984). "Bicuculline-insensitive GABA receptors: studies on the binding of (−)-baclofen to rat cerebellar membranes".
1542:"International Union of Pharmacology. XV. Subtypes of gamma-aminobutyric acidA receptors: classification on the basis of subunit structure and receptor function"
326:
185:
44:
1505:
Kusama T, Wang TL, Guggino WB, Cutting GR, Uhl GR (March 1993). "GABA rho 2 receptor pharmacological profile: GABA recognition site similarities to rho 1".
4721:
3785:
2078:
2838:
4093:
3604:
4759:
4754:
4158:
3609:
209:
68:
4231:
4181:
3096:
2071:
1768:
4342:
3121:
569:
receptors are large enough to justify maintaining the distinction between these two subclasses of GABA receptors. However, since GABA
4334:
4211:
2831:
2494:
2482:
4419:
2877:
4261:
4236:
4764:
2514:
2391:
338:
197:
56:
1913:
Sieghart W, Ernst M (2005). "Heterogeneity of GABAA receptors: Revived interest in the development of subtype-selective drugs".
331:
190:
49:
4304:
4063:
3765:
2527:
4241:
1229:
Feigenspan A, Wässle H, Bormann J (January 1993). "Pharmacology of GABA receptor Cl channels in rat retinal bipolar cells".
1764:"Response kinetics and pharmacological properties of heteromeric receptors formed by coassembly of GABA ρ- and γ2-subunits"
1572:
Chebib M, Johnston GA (April 2000). "GABA-Activated ligand gated ion channels: medicinal chemistry and molecular biology".
4391:
4246:
4714:
4251:
4226:
3135:
4118:
3654:
3649:
3644:
1003:
850:
3639:
3634:
1940:
Chebib M, Johnston GA (2000). "GABA-Activated ligand gated ion channels: medicinal chemistry and molecular biology".
4028:
2549:
2506:
1540:
Barnard EA, Skolnick P, Olsen RW, Mohler H, Sieghart W, Biggio G, Braestrup C, Bateson AN, Langer SZ (June 1998).
4508:
4498:
4352:
4043:
3924:
2868:
2349:
4309:
4176:
3091:
3061:
2063:
2563:
2102:
1815:"Evidence for inhibition mediated by coassembly of GABAA and GABAC receptor subunits in native central neurons"
626:
459:
4256:
4289:
4503:
4478:
4133:
2936:
475:
3899:
3760:
3494:
2750:
343:
4658:
4274:
2926:
202:
61:
3740:
2098:
511:
3539:
4463:
4128:
3983:
3619:
3130:
2931:
1289:
1238:
981:
974:
964:
832:
384:
255:
114:
3469:
1280:
Qian H, Dowling JE (January 1993). "Novel GABA responses from rod-driven retinal horizontal cells".
4513:
4493:
3988:
3977:
3614:
3318:
3140:
3031:
2763:
978:
4693:
3702:
3374:
3336:
2991:
2981:
2860:
2566:
2110:
1895:
1716:
1399:
1356:
1313:
1262:
1172:
1088:
1045:
642:
receptor current has a rapid onset and short duration. GABA is about 10 times more potent at GABA
630:
622:
3795:
3559:
593:
term no longer be used and these ρ receptors should be designated as the ρ subfamily of the GABA
4653:
4648:
4643:
4638:
4633:
4598:
4269:
4013:
969:
956:
950:
711:
699:
687:
4623:
4608:
4483:
4324:
4319:
4294:
4053:
3955:
3889:
3584:
3346:
3193:
3148:
2986:
2971:
2966:
2941:
2050:
2001:
1957:
1887:
1846:
1795:
1744:
1708:
1673:
1624:
1589:
1554:
1541:
1522:
1487:
1434:
1391:
1348:
1305:
1254:
1211:
1164:
1129:
1080:
1037:
3805:
3564:
4613:
4448:
4201:
3859:
3659:
3589:
3424:
3322:
3154:
3035:
2608:
2341:
2040:
2032:
1993:
1949:
1922:
1877:
1836:
1826:
1785:
1777:
1700:
1663:
1655:
1616:
1581:
1514:
1477:
1469:
1383:
1340:
1297:
1246:
1203:
1156:
1119:
1072:
1029:
671:
467:
379:
250:
109:
388:
3960:
3869:
3834:
3502:
3484:
3409:
3366:
3229:
1546:
1007:
667:
479:
408:
279:
138:
1418:
259:
118:
1293:
1242:
1020:
Sivilotti L, Nistri A (1991). "GABA receptor mechanisms in the central nervous system".
4543:
4438:
3488:
3358:
3350:
3253:
3179:
3144:
2175:
2127:
2045:
2020:
1841:
1814:
1790:
1763:
1668:
1643:
1482:
1473:
1453:
828:
781:
774:
751:
519:
447:
1704:
1620:
1207:
4769:
4748:
4453:
4143:
3950:
3838:
3819:
3755:
3682:
3594:
3544:
3510:
3473:
3434:
3384:
3224:
3219:
3209:
3173:
3076:
3011:
2961:
2910:
2854:
2653:
2583:
2167:
2119:
1882:
1865:
1518:
1387:
1190:
Zhang D, Pan ZH, Awobuluyi M, Lipton SA (March 2001). "Structure and function of GABA
1160:
1124:
1107:
1076:
1033:
925:
618:
2021:"Mutation analysis of GABRR1 and GABRR2 in autosomal recessive retinitis pigmentosa"
1899:
1720:
1403:
1360:
1092:
1049:
355:
4410:
4381:
4375:
4186:
3973:
3936:
3932:
3854:
3750:
3438:
3413:
3389:
3111:
2916:
2771:
1831:
1317:
1266:
1176:
750:
There is also evidence that ρ1 subunits can form hetero-pentameric complexes with
638:-ρ receptors is slow to initiate but sustained in duration. In contrast, the GABA
226:
85:
4663:
4588:
4523:
4362:
4299:
4206:
4148:
4058:
3928:
3919:
3879:
3674:
3534:
3529:
3518:
3514:
3464:
3454:
3341:
3326:
3308:
3203:
3169:
3026:
2976:
2956:
2906:
2094:
824:
813:
719:
The above three subunits coassemble either to form functional homo-pentamers (ρ1
523:
418:
289:
148:
1997:
625:
of chloride is less than the membrane potential, chloride ions flow down their
621:. Binding of GABA to the receptor results in opening of this channel. When the
545:
receptors are exclusively composed of ρ (rho) subunits that are related to GABA
4548:
4458:
4367:
4357:
4216:
4033:
4023:
4008:
4003:
3998:
3965:
3944:
3914:
3849:
3829:
3823:
3725:
3692:
3686:
3678:
3579:
3574:
3569:
3554:
3506:
3479:
3444:
3419:
3278:
3273:
3267:
3214:
3163:
3159:
3046:
2901:
507:
362:
233:
92:
1926:
4683:
4678:
4668:
4628:
4573:
4558:
4538:
4533:
4518:
4314:
4284:
4191:
4171:
4166:
4018:
3940:
3874:
3844:
3815:
3745:
3730:
3697:
3664:
3428:
3404:
3362:
3354:
3313:
3303:
3287:
3283:
3259:
3244:
3239:
3199:
3116:
3101:
3066:
3056:
3041:
3016:
2996:
2951:
1452:
Kusama T, Spivak CE, Whiting P, Dawson VL, Schaeffer JC, Uhl GR (May 1993).
2823:
2054:
2005:
1961:
1891:
1850:
1799:
1781:
1748:
1677:
1628:
1593:
1215:
1000:
1813:
Milligan CJ, Buckley NJ, Garret M, Deuchars J, Deuchars SA (August 2004).
1712:
1558:
1526:
1491:
1438:
1395:
1352:
1309:
1258:
1168:
1133:
1084:
1041:
573:
receptors are closely related in sequence, structure, and function to GABA
4673:
4603:
4593:
4553:
4528:
4468:
4371:
4279:
4153:
4083:
4038:
3969:
3909:
3894:
3809:
3770:
3669:
3549:
3458:
3398:
3378:
3370:
3263:
3249:
3233:
3183:
3081:
3071:
3051:
3021:
3005:
2896:
2019:
Marcos I, Ruiz A, Blaschak CJ, Borrego S, Cutting GR, Antinolo G (1998).
1659:
865:
805:
663:
614:
367:
238:
97:
2036:
1331:
Lukasiewicz PD (June 1996). "GABAC receptors in the vertebrate retina".
486:, is expressed in many areas of the brain, but in contrast to other GABA
4578:
4563:
4473:
4386:
4113:
4073:
4068:
3993:
3904:
3884:
3800:
3629:
3624:
3449:
3189:
3105:
3086:
2921:
2698:
2693:
2442:
1344:
977:. Mutations in the ρ1 or ρ2 genes may be responsible for some cases of
802:
1953:
1691:
Enz R, Cutting GR (1998). "Molecular composition of GABAC receptors".
1585:
4443:
3394:
3297:
3001:
2688:
2683:
2678:
2673:
2668:
2663:
2462:
2457:
2452:
2447:
2437:
2432:
2427:
2422:
2417:
2412:
2407:
2402:
2326:
2318:
2310:
2271:
2263:
2255:
2247:
2239:
2231:
2223:
2215:
2207:
2199:
2191:
1301:
1250:
1108:"GABAc receptors: relatively simple transmitter -gated ion channels?"
758:
706:
694:
682:
561:
receptor family. Others have argued that the differences between GABA
535:
495:
350:
319:
304:
221:
178:
163:
80:
37:
22:
581:
receptors besides those containing ρ subunits appear to exhibit GABA
1866:"Interactions between rho and gamma2 subunits of the GABA receptor"
769:
There are several pharmacological differences that distinguish GABA
462:
responsible for mediating the effects of gamma-amino butyric acid (
4488:
4138:
3864:
3714:
3330:
2946:
2806:
2801:
2796:
2791:
2786:
2781:
2776:
2731:
2723:
2658:
2633:
2628:
2623:
2618:
2613:
2602:
2597:
2592:
2587:
2472:
2467:
2373:
2365:
2357:
2294:
2289:
2284:
2279:
2155:
2150:
2145:
2140:
2135:
945:
860:
1194:
receptors: a comparison of native versus recombinant receptors".
4583:
4396:
4078:
4048:
3790:
3780:
3720:
3710:
3706:
3293:
2381:
960:
463:
214:
73:
2827:
2067:
3498:
1454:"Pharmacology of GABA ρ1 and GABA α/β receptors expressed in
1063:
Bormann J, Feigenspan A (December 1995). "GABAC receptors".
4094:
674:
to form a central ion conducting pore. To date, three GABA
1607:
Bormann J (January 2000). "The 'ABC' of GABA receptors".
795:
selectively activated by (+)-CAMP and blocked by TPMPA ;
629:
into the cell. This influx of chloride ions lowers the
609:
In addition to containing a GABA binding site, the GABA
538:
bipolar or horizontal cells across vertebrate species.
4420:
2878:
678:-ρ receptor subunits have been identified in humans:
4418:
4409:
4092:
2876:
2867:
2762:
2749:
2709:
2644:
2574:
2562:
2540:
2390:
2340:
2166:
2118:
2109:
414:
404:
399:
378:
373:
361:
349:
337:
325:
315:
310:
303:
285:
275:
270:
249:
244:
232:
220:
208:
196:
184:
174:
169:
162:
144:
134:
129:
108:
103:
91:
79:
67:
55:
43:
33:
28:
21:
494:-ρ receptor has especially high expression in the
922:(S)-(4-Aminocyclopent-1-enyl)butylphosphinic acid
896:CGP-36742 (3-aminopropyl-n-butyl-phosphinic acid)
893:SKF-97541 (3-Aminopropyl(methyl)phosphinic acid)
585:pharmacology, the Nomenclature Committee of the
458:receptors including those of the ρ-subclass are
658:Like other ligand-gated ion channels, the GABA
305:gamma-aminobutyric acid (GABA) receptor, rho 3
164:gamma-aminobutyric acid (GABA) receptor, rho 2
23:gamma-aminobutyric acid (GABA) receptor, rho 1
2839:
2079:
8:
1986:Bioorganic & Medicinal Chemistry Letters
2855:
1417:Shimada S, Cutting G, Uhl GR (April 1992).
831:, but are modulated selectively by certain
454:composed entirely of rho (ρ) subunits. GABA
4415:
4103:Tooltip γ-Aminobutyric acid A-rho receptor
2873:
2846:
2832:
2824:
2759:
2571:
2115:
2086:
2072:
2064:
557:may be viewed as a variant within the GABA
549:receptor subunits. Although the term "GABA
396:
267:
126:
2044:
1881:
1840:
1830:
1789:
1667:
1481:
1123:
919:-(3-Aminocyclopentyl)butylphosphinic acid
1001:GABAc receptors in the vertebrate retina
1642:Olsen RW, Sieghart W (September 2008).
992:
4428:Tooltip γ-Aminobutyric acid B receptor
2886:Tooltip γ-Aminobutyric acid A receptor
530:receptor. Native responses of the GABA
510:GABA receptor, insensitive to typical
300:
159:
18:
7:
4733:GABA metabolism/transport modulators
3129:Positive modulators (abridged; see
944:-ρ receptor subunits ρ1 and ρ2 are
1769:Proceedings of the Royal Society B
1474:10.1111/j.1476-5381.1993.tb13554.x
553:receptor" is frequently used, GABA
14:
4664:Homotaurine (tramiprosate, 3-APS)
4162:-Chloroacetylcytosine arabinoside
2957:Homotaurine (tramiprosate, 3-APS)
1010:. Retrieved on February 14, 2007.
662:-ρ chloride channel is formed by
1883:10.1111/j.1471-4159.2005.03225.x
1388:10.1046/j.1460-9568.1998.00023.x
3956:Pentylenetetrazol (pentetrazol)
1832:10.1523/JNEUROSCI.1979-04.2004
1106:Johnston GA (September 1996).
890:ZAPA ((Z)-3-prop-2-enoic acid)
577:receptors and since other GABA
1:
4715:Receptor/signaling modulators
3870:Isopregnanolone (sepranolone)
1705:10.1016/S0042-6989(97)00277-0
1621:10.1016/S0165-6147(99)01413-3
1208:10.1016/S0165-6147(00)01625-4
613:-ρ receptor complex conducts
589:has recommended that the GABA
4726:receptor positive modulators
3234:ergoloid (dihydroergotoxine)
1519:10.1016/0922-4106(93)90174-8
1161:10.1016/0304-3940(84)90181-2
1125:10.1016/0165-6147(96)10038-9
1077:10.1016/0166-2236(95)98370-E
1034:10.1016/0301-0082(91)90036-Z
823:receptor modulators such as
787:receptors. For example, GABA
4760:Genes on human chromosome 3
4755:Genes on human chromosome 6
1915:Current Medicinal Chemistry
1864:Pan Y, Qian H (July 2005).
16:Class of transport proteins
4786:
3925:Nonsteroidal antiandrogens
1998:10.1016/j.bmcl.2007.10.019
819:not modulated by many GABA
670:arranged about a fivefold
646:-ρ than it is at most GABA
518:receptor channels such as
4706:
2646:Voltage- and ligand-gated
2103:ligand-gated ion channels
1870:Journal of Neurochemistry
798:not sensitive to the GABA
731:) or hetero-pentamers (ρ1
460:ligand-gated ion channels
438:(previously known as the
395:
266:
125:
3474:sulfonmethane (sulfonal)
1927:10.2174/1568015054863837
1762:Qian H, Ripps H (1999).
973:gene for ρ3 is found on
627:electrochemical gradient
466:), the major inhibitory
4765:Transmembrane receptors
2392:Nicotinic acetylcholine
1819:Journal of Neuroscience
1648:Pharmacological Reviews
534:receptor type occur in
4353:5α-Dihydroprogesterone
3900:Morphine-3-glucuronide
3560:Hyenachin (mellitoxin)
3445:Retigabine (ezogabine)
1782:10.1098/rspb.1999.0941
1458:oocytes and COS cells"
470:in the brain. The GABA
3741:Chlorophenylsilatrane
2099:cell surface receptor
1609:Trends Pharmacol. Sci
1196:Trends Pharmacol. Sci
1112:Trends Pharmacol. Sci
617:ions across neuronal
526:, was designated GABA
512:allosteric modulators
4691:Negative modulators:
4571:Positive modulators:
4464:Arbaclofen placarbil
4350:Negative modulators:
4199:Positive modulators:
3984:Pregnenolone sulfate
3620:17-Phenylandrostenol
3602:Negative modulators:
3487:constituents (e.g.,
3457:constituents (e.g.,
3319:Neuroactive steroids
3296:constituents (e.g.,
3032:Neuroactive steroids
2764:Purinergic receptors
1660:10.1124/pr.108.00505
982:retinitis pigmentosa
833:neuroactive steroids
812:receptor antagonist
4280:Gabazine (SR-95531)
4270:CGP-36742 (SGS-742)
3978:dihydropicrotoxinin
3703:Bicyclic phosphates
3615:11-Ketoprogesterone
3550:Gabazine (SR-95531)
3375:pyrazolopyrimidines
2037:10.1136/jmg.37.6.e5
1776:(1436): 2419–2425.
1294:1993Natur.361..162Q
1243:1993Natur.361..159F
979:autosomal recessive
963:which are found on
490:receptors, the GABA
446:) is a subclass of
3801:FG-7142 (ZK-31906)
3347:Nonbenzodiazepines
2532:β1δε - Muscle type
2111:Cys-loop receptors
1737:Receptors Channels
1345:10.1007/BF02755587
1006:2010-12-31 at the
791:-ρ receptors are:
747:where m + n = 5).
631:membrane potential
623:reversal potential
4742:
4741:
4702:
4701:
4624:2-Hydroxysaclofen
4405:
4404:
4295:Isonipecotic acid
3660:Anabolic steroids
3630:α5IA (LS-193,268)
3540:Dihydrosecurinine
3425:Pyrazolopyridines
3194:potassium bromide
3192:compounds (e.g.,
3155:Anabolic steroids
3133:for a full list):
2987:Isonipecotic acid
2821:
2820:
2817:
2816:
2745:
2744:
2576:Ligand-gated only
2558:
2557:
1954:10.1021/jm9904349
1825:(33): 7241–7250.
1699:(10): 1431–1441.
1586:10.1021/jm9904349
1507:Eur. J. Pharmacol
1288:(6408): 162–164.
1237:(6408): 159–162.
840:Selective Ligands
506:A second type of
428:
427:
424:
423:
299:
298:
295:
294:
158:
157:
154:
153:
4777:
4449:4-Fluorophenibut
4429:
4425:
4416:
4285:Gaboxadol (THIP)
4202:Allopregnanolone
4104:
4100:
3835:Fluoroquinolones
3590:Thiocolchicoside
3410:Piperidinediones
3367:imidazopyridines
3323:allopregnanolone
3230:Dihydroergolines
3145:drinking alcohol
3036:allopregnanolone
2952:Gaboxadol (THIP)
2887:
2883:
2874:
2857:
2848:
2841:
2834:
2825:
2760:
2572:
2116:
2088:
2081:
2074:
2065:
2059:
2058:
2048:
2016:
2010:
2009:
1981:
1975:
1972:
1966:
1965:
1948:(8): 1427–1447.
1937:
1931:
1930:
1910:
1904:
1903:
1885:
1861:
1855:
1854:
1844:
1834:
1810:
1804:
1803:
1793:
1759:
1753:
1752:
1731:
1725:
1724:
1688:
1682:
1681:
1671:
1639:
1633:
1632:
1604:
1598:
1597:
1580:(8): 1427–1447.
1569:
1563:
1562:
1537:
1531:
1530:
1502:
1496:
1495:
1485:
1462:Br. J. Pharmacol
1449:
1443:
1442:
1414:
1408:
1407:
1376:Eur. J. Neurosci
1371:
1365:
1364:
1328:
1322:
1321:
1302:10.1038/361162a0
1277:
1271:
1270:
1251:10.1038/361159a0
1226:
1220:
1219:
1187:
1181:
1180:
1144:
1138:
1137:
1127:
1103:
1097:
1096:
1060:
1054:
1053:
1017:
1011:
997:
468:neurotransmitter
397:
301:
268:
160:
127:
19:
4785:
4784:
4780:
4779:
4778:
4776:
4775:
4774:
4745:
4744:
4743:
4738:
4725:
4698:
4427:
4424:
4401:
4129:Homohypotaurine
4102:
4098:
4088:
3961:Phenylsilatrane
3503:chloral hydrate
3470:Sulfonylalkanes
3359:cyclopyrrolones
3180:Benzodiazepines
2932:Dihydromuscimol
2885:
2882:
2863:
2852:
2822:
2813:
2741:
2735:
2727:
2705:
2640:
2554:
2536:
2531:
2523:- Ganglion type
2522:
2518:
2510:
2502:
2498:
2490:
2486:
2386:
2377:
2369:
2361:
2353:
2336:
2330:
2322:
2314:
2305:
2275:
2267:
2259:
2251:
2243:
2235:
2227:
2219:
2211:
2203:
2195:
2187:
2179:
2162:
2131:
2105:
2092:
2062:
2018:
2017:
2013:
1983:
1982:
1978:
1973:
1969:
1939:
1938:
1934:
1912:
1911:
1907:
1863:
1862:
1858:
1812:
1811:
1807:
1761:
1760:
1756:
1733:
1732:
1728:
1690:
1689:
1685:
1641:
1640:
1636:
1606:
1605:
1601:
1571:
1570:
1566:
1547:Pharmacol. Rev.
1539:
1538:
1534:
1504:
1503:
1499:
1451:
1450:
1446:
1416:
1415:
1411:
1373:
1372:
1368:
1330:
1329:
1325:
1279:
1278:
1274:
1228:
1227:
1223:
1193:
1189:
1188:
1184:
1146:
1145:
1141:
1105:
1104:
1100:
1071:(12): 515–519.
1065:Trends Neurosci
1062:
1061:
1057:
1022:Prog. Neurobiol
1019:
1018:
1014:
1008:Wayback Machine
998:
994:
990:
943:
940:In humans, GABA
938:
929:
904:
884:
880:
874:
847:
842:
829:benzodiazepines
822:
811:
801:
790:
785:
778:
772:
767:
755:
746:
742:
738:
734:
730:
726:
722:
677:
664:oligomerization
661:
656:
649:
645:
641:
637:
612:
607:
600:
597:receptors (GABA
596:
592:
584:
580:
576:
572:
568:
564:
560:
556:
552:
548:
544:
533:
529:
520:benzodiazepines
517:
504:
493:
489:
483:
473:
457:
451:
443:
435:
17:
12:
11:
5:
4783:
4781:
4773:
4772:
4767:
4762:
4757:
4747:
4746:
4740:
4739:
4737:
4736:
4729:
4723:
4718:
4711:
4707:
4704:
4703:
4700:
4699:
4697:
4696:
4687:
4686:
4681:
4676:
4671:
4666:
4661:
4656:
4651:
4646:
4641:
4636:
4631:
4626:
4617:
4616:
4611:
4606:
4601:
4596:
4591:
4586:
4581:
4576:
4567:
4566:
4561:
4556:
4551:
4546:
4544:Sodium oxybate
4541:
4536:
4531:
4526:
4521:
4516:
4511:
4506:
4501:
4496:
4491:
4486:
4481:
4476:
4471:
4466:
4461:
4456:
4451:
4446:
4441:
4439:1,4-Butanediol
4432:
4430:
4422:
4413:
4407:
4406:
4403:
4402:
4400:
4399:
4394:
4389:
4384:
4379:
4365:
4360:
4355:
4346:
4345:
4340:
4332:
4327:
4322:
4317:
4312:
4307:
4302:
4297:
4292:
4287:
4282:
4277:
4272:
4267:
4259:
4254:
4249:
4244:
4239:
4234:
4229:
4220:
4219:
4214:
4209:
4204:
4195:
4194:
4189:
4184:
4179:
4174:
4169:
4164:
4156:
4151:
4146:
4141:
4136:
4131:
4126:
4121:
4116:
4107:
4105:
4096:
4090:
4089:
4087:
4086:
4081:
4076:
4071:
4066:
4061:
4056:
4051:
4046:
4041:
4036:
4031:
4026:
4021:
4016:
4011:
4006:
4001:
3996:
3991:
3986:
3981:
3963:
3958:
3953:
3948:
3922:
3917:
3912:
3907:
3902:
3897:
3892:
3887:
3882:
3877:
3872:
3867:
3862:
3857:
3852:
3847:
3842:
3832:
3827:
3813:
3803:
3798:
3793:
3788:
3783:
3778:
3773:
3768:
3763:
3758:
3753:
3748:
3743:
3738:
3733:
3728:
3723:
3718:
3700:
3695:
3690:
3683:cephalosporins
3672:
3667:
3662:
3657:
3652:
3647:
3642:
3637:
3632:
3627:
3622:
3617:
3612:
3607:
3598:
3597:
3592:
3587:
3582:
3577:
3572:
3567:
3562:
3557:
3552:
3547:
3542:
3537:
3532:
3523:
3522:
3492:
3489:valerenic acid
3482:
3477:
3467:
3462:
3452:
3447:
3442:
3435:Quinazolinones
3432:
3422:
3417:
3407:
3402:
3392:
3387:
3382:
3344:
3339:
3334:
3316:
3311:
3306:
3301:
3291:
3281:
3276:
3271:
3257:
3254:mefenamic acid
3247:
3242:
3237:
3227:
3222:
3217:
3212:
3207:
3197:
3187:
3177:
3167:
3157:
3152:
3138:
3125:
3124:
3119:
3114:
3109:
3099:
3094:
3089:
3084:
3079:
3074:
3069:
3064:
3059:
3054:
3049:
3044:
3039:
3029:
3024:
3019:
3014:
3009:
2999:
2994:
2989:
2984:
2979:
2974:
2969:
2964:
2959:
2954:
2949:
2944:
2939:
2934:
2929:
2924:
2919:
2914:
2904:
2899:
2890:
2888:
2880:
2871:
2865:
2864:
2853:
2851:
2850:
2843:
2836:
2828:
2819:
2818:
2815:
2814:
2812:
2811:
2810:
2809:
2804:
2799:
2794:
2789:
2784:
2779:
2768:
2766:
2757:
2755:gated channels
2747:
2746:
2743:
2742:
2740:
2739:
2738:
2737:
2733:
2729:
2725:
2715:
2713:
2707:
2706:
2704:
2703:
2702:
2701:
2696:
2691:
2686:
2681:
2676:
2671:
2666:
2661:
2650:
2648:
2642:
2641:
2639:
2638:
2637:
2636:
2631:
2626:
2621:
2616:
2606:
2600:
2595:
2590:
2580:
2578:
2569:
2560:
2559:
2556:
2555:
2553:
2552:
2550:Zinc-activated
2546:
2544:
2538:
2537:
2535:
2534:
2529:
2525:
2520:
2516:
2512:
2508:
2504:
2500:
2496:
2492:
2488:
2484:
2476:
2475:
2470:
2465:
2460:
2455:
2450:
2445:
2440:
2435:
2430:
2425:
2420:
2415:
2410:
2405:
2396:
2394:
2388:
2387:
2385:
2384:
2379:
2375:
2371:
2367:
2363:
2359:
2355:
2351:
2346:
2344:
2338:
2337:
2335:
2334:
2333:
2332:
2328:
2324:
2320:
2316:
2312:
2303:
2299:
2298:
2297:
2292:
2287:
2282:
2277:
2273:
2269:
2265:
2261:
2257:
2253:
2249:
2245:
2241:
2237:
2233:
2229:
2225:
2221:
2217:
2213:
2209:
2205:
2201:
2197:
2193:
2189:
2185:
2177:
2172:
2170:
2164:
2163:
2161:
2160:
2159:
2158:
2153:
2148:
2143:
2138:
2129:
2124:
2122:
2120:5-HT/serotonin
2113:
2107:
2106:
2093:
2091:
2090:
2083:
2076:
2068:
2061:
2060:
2011:
1992:(1): 402–404.
1976:
1967:
1932:
1921:(3): 217–242.
1905:
1876:(2): 482–490.
1856:
1805:
1754:
1743:(6): 463–475.
1726:
1683:
1654:(3): 243–260.
1634:
1599:
1564:
1553:(2): 291–313.
1532:
1497:
1468:(1): 200–206.
1444:
1433:(4): 683–687.
1427:Mol. Pharmacol
1409:
1382:(1): 350–357.
1366:
1339:(3): 181–194.
1333:Mol. Neurobiol
1323:
1272:
1221:
1202:(3): 121–132.
1191:
1182:
1155:(3): 317–321.
1149:Neurosci. Lett
1139:
1118:(9): 319–323.
1098:
1055:
1012:
999:Qian H. 2000.
991:
989:
986:
941:
937:
934:
933:
932:
927:
923:
920:
913:
907:
906:
905:-ρ antagonists
902:
901:Selective GABA
898:
897:
894:
891:
887:
886:
882:
878:
873:
870:
869:
868:
863:
858:
853:
846:
843:
841:
838:
837:
836:
820:
817:
809:
799:
796:
788:
783:
776:
770:
766:
763:
753:
744:
740:
736:
732:
728:
724:
720:
717:
716:
704:
692:
675:
659:
655:
652:
647:
643:
639:
635:
610:
606:
603:
598:
594:
590:
582:
578:
574:
570:
566:
562:
558:
554:
550:
546:
542:
531:
527:
515:
503:
500:
491:
487:
481:
471:
455:
449:
441:
433:
426:
425:
422:
421:
416:
412:
411:
406:
402:
401:
393:
392:
382:
376:
375:
371:
370:
365:
359:
358:
353:
347:
346:
341:
335:
334:
329:
323:
322:
317:
313:
312:
308:
307:
297:
296:
293:
292:
287:
283:
282:
277:
273:
272:
264:
263:
253:
247:
246:
242:
241:
236:
230:
229:
224:
218:
217:
212:
206:
205:
200:
194:
193:
188:
182:
181:
176:
172:
171:
167:
166:
156:
155:
152:
151:
146:
142:
141:
136:
132:
131:
123:
122:
112:
106:
105:
101:
100:
95:
89:
88:
83:
77:
76:
71:
65:
64:
59:
53:
52:
47:
41:
40:
35:
31:
30:
26:
25:
15:
13:
10:
9:
6:
4:
3:
2:
4782:
4771:
4768:
4766:
4763:
4761:
4758:
4756:
4753:
4752:
4750:
4735:
4734:
4730:
4728:
4727:
4719:
4717:
4716:
4712:
4709:
4708:
4705:
4695:
4692:
4689:
4688:
4685:
4682:
4680:
4677:
4675:
4672:
4670:
4667:
4665:
4662:
4660:
4657:
4655:
4652:
4650:
4647:
4645:
4642:
4640:
4637:
4635:
4632:
4630:
4627:
4625:
4622:
4619:
4618:
4615:
4612:
4610:
4607:
4605:
4602:
4600:
4597:
4595:
4592:
4590:
4587:
4585:
4582:
4580:
4577:
4575:
4572:
4569:
4568:
4565:
4562:
4560:
4557:
4555:
4552:
4550:
4547:
4545:
4542:
4540:
4537:
4535:
4532:
4530:
4527:
4525:
4522:
4520:
4517:
4515:
4512:
4510:
4507:
4505:
4502:
4500:
4497:
4495:
4492:
4490:
4487:
4485:
4482:
4480:
4477:
4475:
4472:
4470:
4467:
4465:
4462:
4460:
4457:
4455:
4454:Aceburic acid
4452:
4450:
4447:
4445:
4442:
4440:
4437:
4434:
4433:
4431:
4426:
4417:
4414:
4412:
4408:
4398:
4395:
4393:
4390:
4388:
4385:
4383:
4380:
4377:
4373:
4369:
4366:
4364:
4361:
4359:
4356:
4354:
4351:
4348:
4347:
4344:
4341:
4339:
4337:
4333:
4331:
4328:
4326:
4323:
4321:
4318:
4316:
4313:
4311:
4308:
4306:
4303:
4301:
4298:
4296:
4293:
4291:
4288:
4286:
4283:
4281:
4278:
4276:
4273:
4271:
4268:
4266:
4264:
4260:
4258:
4255:
4253:
4250:
4248:
4245:
4243:
4240:
4238:
4235:
4233:
4230:
4228:
4225:
4222:
4221:
4218:
4215:
4213:
4210:
4208:
4205:
4203:
4200:
4197:
4196:
4193:
4190:
4188:
4185:
4183:
4180:
4178:
4175:
4173:
4170:
4168:
4165:
4163:
4161:
4157:
4155:
4152:
4150:
4147:
4145:
4144:Ibotenic acid
4142:
4140:
4137:
4135:
4132:
4130:
4127:
4125:
4122:
4120:
4117:
4115:
4112:
4109:
4108:
4106:
4101:
4091:
4085:
4082:
4080:
4077:
4075:
4072:
4070:
4067:
4065:
4062:
4060:
4057:
4055:
4052:
4050:
4047:
4045:
4042:
4040:
4037:
4035:
4032:
4030:
4027:
4025:
4022:
4020:
4017:
4015:
4012:
4010:
4007:
4005:
4002:
4000:
3997:
3995:
3992:
3990:
3989:Propybicyphat
3987:
3985:
3982:
3979:
3975:
3971:
3967:
3964:
3962:
3959:
3957:
3954:
3952:
3951:Oenanthotoxin
3949:
3946:
3942:
3938:
3934:
3930:
3926:
3923:
3921:
3918:
3916:
3913:
3911:
3908:
3906:
3903:
3901:
3898:
3896:
3893:
3891:
3888:
3886:
3883:
3881:
3878:
3876:
3873:
3871:
3868:
3866:
3863:
3861:
3860:Iomazenil (I)
3858:
3856:
3853:
3851:
3848:
3846:
3843:
3840:
3839:ciprofloxacin
3836:
3833:
3831:
3828:
3825:
3821:
3820:amentoflavone
3817:
3814:
3811:
3807:
3804:
3802:
3799:
3797:
3794:
3792:
3789:
3787:
3784:
3782:
3779:
3777:
3774:
3772:
3769:
3767:
3764:
3762:
3759:
3757:
3756:Cyclothiazide
3754:
3752:
3749:
3747:
3744:
3742:
3739:
3737:
3734:
3732:
3729:
3727:
3724:
3722:
3719:
3716:
3712:
3708:
3704:
3701:
3699:
3696:
3694:
3691:
3688:
3684:
3680:
3676:
3673:
3671:
3668:
3666:
3663:
3661:
3658:
3656:
3653:
3651:
3648:
3646:
3643:
3641:
3638:
3636:
3633:
3631:
3628:
3626:
3623:
3621:
3618:
3616:
3613:
3611:
3608:
3606:
3603:
3600:
3599:
3596:
3593:
3591:
3588:
3586:
3583:
3581:
3578:
3576:
3573:
3571:
3568:
3566:
3563:
3561:
3558:
3556:
3553:
3551:
3548:
3546:
3545:Famiraprinium
3543:
3541:
3538:
3536:
3533:
3531:
3528:
3525:
3524:
3520:
3516:
3512:
3511:diethyl ether
3508:
3504:
3500:
3496:
3493:
3490:
3486:
3483:
3481:
3478:
3475:
3471:
3468:
3466:
3463:
3460:
3456:
3453:
3451:
3448:
3446:
3443:
3440:
3436:
3433:
3430:
3426:
3423:
3421:
3418:
3415:
3411:
3408:
3406:
3403:
3400:
3396:
3393:
3391:
3388:
3386:
3385:Norfluoxetine
3383:
3380:
3376:
3372:
3368:
3364:
3360:
3356:
3352:
3348:
3345:
3343:
3340:
3338:
3335:
3332:
3328:
3324:
3320:
3317:
3315:
3312:
3310:
3307:
3305:
3302:
3299:
3295:
3292:
3289:
3285:
3282:
3280:
3277:
3275:
3272:
3269:
3265:
3261:
3258:
3255:
3251:
3248:
3246:
3243:
3241:
3238:
3235:
3231:
3228:
3226:
3225:Clomethiazole
3223:
3221:
3220:Chlormezanone
3218:
3216:
3213:
3211:
3210:Carbamazepine
3208:
3205:
3201:
3198:
3195:
3191:
3188:
3185:
3181:
3178:
3175:
3174:phenobarbital
3171:
3168:
3165:
3161:
3158:
3156:
3153:
3150:
3146:
3142:
3139:
3137:
3134:
3132:
3127:
3126:
3123:
3120:
3118:
3115:
3113:
3110:
3107:
3103:
3100:
3098:
3095:
3093:
3090:
3088:
3085:
3083:
3080:
3078:
3077:Quisqualamine
3075:
3073:
3070:
3068:
3065:
3063:
3060:
3058:
3055:
3053:
3050:
3048:
3045:
3043:
3040:
3037:
3033:
3030:
3028:
3025:
3023:
3020:
3018:
3015:
3013:
3012:Methylglyoxal
3010:
3007:
3003:
3000:
2998:
2995:
2993:
2990:
2988:
2985:
2983:
2980:
2978:
2975:
2973:
2970:
2968:
2965:
2963:
2962:Ibotenic acid
2960:
2958:
2955:
2953:
2950:
2948:
2945:
2943:
2940:
2938:
2935:
2933:
2930:
2928:
2925:
2923:
2920:
2918:
2915:
2912:
2911:phenobarbital
2908:
2905:
2903:
2900:
2898:
2895:
2892:
2891:
2889:
2884:
2875:
2872:
2870:
2866:
2862:
2859:
2849:
2844:
2842:
2837:
2835:
2830:
2829:
2826:
2808:
2805:
2803:
2800:
2798:
2795:
2793:
2790:
2788:
2785:
2783:
2780:
2778:
2775:
2774:
2773:
2770:
2769:
2767:
2765:
2761:
2758:
2756:
2752:
2748:
2736:
2730:
2728:
2722:
2721:
2720:
2717:
2716:
2714:
2712:
2708:
2700:
2697:
2695:
2692:
2690:
2687:
2685:
2682:
2680:
2677:
2675:
2672:
2670:
2667:
2665:
2662:
2660:
2657:
2656:
2655:
2652:
2651:
2649:
2647:
2643:
2635:
2632:
2630:
2627:
2625:
2622:
2620:
2617:
2615:
2612:
2611:
2610:
2607:
2604:
2601:
2599:
2596:
2594:
2591:
2589:
2585:
2582:
2581:
2579:
2577:
2573:
2570:
2568:
2565:
2561:
2551:
2548:
2547:
2545:
2543:
2539:
2533:
2526:
2524:
2513:
2511:
2505:
2503:
2493:
2491:
2481:
2478:
2477:
2474:
2471:
2469:
2466:
2464:
2461:
2459:
2456:
2454:
2451:
2449:
2446:
2444:
2441:
2439:
2436:
2434:
2431:
2429:
2426:
2424:
2421:
2419:
2416:
2414:
2411:
2409:
2406:
2404:
2401:
2398:
2397:
2395:
2393:
2389:
2383:
2380:
2378:
2372:
2370:
2364:
2362:
2356:
2354:
2348:
2347:
2345:
2343:
2339:
2331:
2325:
2323:
2317:
2315:
2309:
2308:
2307:
2300:
2296:
2293:
2291:
2288:
2286:
2283:
2281:
2278:
2276:
2270:
2268:
2262:
2260:
2254:
2252:
2246:
2244:
2238:
2236:
2230:
2228:
2222:
2220:
2214:
2212:
2206:
2204:
2198:
2196:
2190:
2188:
2182:
2181:
2180:
2174:
2173:
2171:
2169:
2165:
2157:
2154:
2152:
2149:
2147:
2144:
2142:
2139:
2137:
2134:
2133:
2132:
2126:
2125:
2123:
2121:
2117:
2114:
2112:
2108:
2104:
2100:
2096:
2089:
2084:
2082:
2077:
2075:
2070:
2069:
2066:
2056:
2052:
2047:
2042:
2038:
2034:
2030:
2026:
2022:
2015:
2012:
2007:
2003:
1999:
1995:
1991:
1987:
1980:
1977:
1971:
1968:
1963:
1959:
1955:
1951:
1947:
1943:
1936:
1933:
1928:
1924:
1920:
1916:
1909:
1906:
1901:
1897:
1893:
1889:
1884:
1879:
1875:
1871:
1867:
1860:
1857:
1852:
1848:
1843:
1838:
1833:
1828:
1824:
1820:
1816:
1809:
1806:
1801:
1797:
1792:
1787:
1783:
1779:
1775:
1771:
1770:
1765:
1758:
1755:
1750:
1746:
1742:
1738:
1730:
1727:
1722:
1718:
1714:
1710:
1706:
1702:
1698:
1694:
1687:
1684:
1679:
1675:
1670:
1665:
1661:
1657:
1653:
1649:
1645:
1638:
1635:
1630:
1626:
1622:
1618:
1614:
1610:
1603:
1600:
1595:
1591:
1587:
1583:
1579:
1575:
1568:
1565:
1560:
1556:
1552:
1549:
1548:
1543:
1536:
1533:
1528:
1524:
1520:
1516:
1512:
1508:
1501:
1498:
1493:
1489:
1484:
1479:
1475:
1471:
1467:
1463:
1459:
1457:
1448:
1445:
1440:
1436:
1432:
1428:
1424:
1422:
1413:
1410:
1405:
1401:
1397:
1393:
1389:
1385:
1381:
1377:
1370:
1367:
1362:
1358:
1354:
1350:
1346:
1342:
1338:
1334:
1327:
1324:
1319:
1315:
1311:
1307:
1303:
1299:
1295:
1291:
1287:
1283:
1276:
1273:
1268:
1264:
1260:
1256:
1252:
1248:
1244:
1240:
1236:
1232:
1225:
1222:
1217:
1213:
1209:
1205:
1201:
1197:
1186:
1183:
1178:
1174:
1170:
1166:
1162:
1158:
1154:
1150:
1143:
1140:
1135:
1131:
1126:
1121:
1117:
1113:
1109:
1102:
1099:
1094:
1090:
1086:
1082:
1078:
1074:
1070:
1066:
1059:
1056:
1051:
1047:
1043:
1039:
1035:
1031:
1027:
1023:
1016:
1013:
1009:
1005:
1002:
996:
993:
987:
985:
983:
980:
976:
972:
971:
966:
962:
959:
958:
953:
952:
947:
935:
931:
924:
921:
918:
914:
912:
909:
908:
900:
899:
895:
892:
889:
888:
876:
875:
871:
867:
864:
862:
859:
857:
854:
852:
849:
848:
844:
839:
834:
830:
826:
818:
815:
807:
804:
797:
794:
793:
792:
786:
779:
764:
762:
760:
757:
748:
714:
713:
708:
705:
702:
701:
696:
693:
690:
689:
684:
681:
680:
679:
673:
672:symmetry axis
669:
665:
653:
651:
632:
628:
624:
620:
616:
604:
602:
588:
539:
537:
525:
521:
513:
509:
501:
499:
497:
485:
478:, like other
477:
469:
465:
461:
453:
445:
437:
436:-rho receptor
420:
417:
413:
410:
407:
403:
398:
394:
391:
390:
386:
383:
381:
377:
372:
369:
366:
364:
360:
357:
354:
352:
348:
345:
342:
340:
336:
333:
330:
328:
324:
321:
318:
314:
309:
306:
302:
291:
288:
284:
281:
278:
274:
269:
265:
262:
261:
257:
254:
252:
248:
243:
240:
237:
235:
231:
228:
225:
223:
219:
216:
213:
211:
207:
204:
201:
199:
195:
192:
189:
187:
183:
180:
177:
173:
168:
165:
161:
150:
147:
143:
140:
137:
133:
128:
124:
121:
120:
116:
113:
111:
107:
102:
99:
96:
94:
90:
87:
84:
82:
78:
75:
72:
70:
66:
63:
60:
58:
54:
51:
48:
46:
42:
39:
36:
32:
27:
24:
20:
4731:
4720:
4713:
4690:
4621:Antagonists:
4620:
4570:
4435:
4411:Metabotropic
4382:Pregnanolone
4376:picrotoxinin
4349:
4335:
4262:
4232:(S)-4-ACPBPA
4227:(S)-2-MeGABA
4224:Antagonists:
4223:
4198:
4187:Thiomuscimol
4159:
4110:
3974:picrotoxinin
3937:enzalutamide
3933:bicalutamide
3855:Golexanolone
3751:Cloflubicyne
3601:
3527:Antagonists:
3526:
3439:methaqualone
3414:glutethimide
3390:Petrichloral
3351:β-carbolines
3170:Barbiturates
3128:
3112:Thiomuscimol
2917:Beta-Alanine
2907:Barbiturates
2897:(+)-Catechin
2893:
2754:
2718:
2710:
2645:
2575:
2541:
2479:
2399:
2301:
2028:
2024:
2014:
1989:
1985:
1979:
1970:
1945:
1941:
1935:
1918:
1914:
1908:
1873:
1869:
1859:
1822:
1818:
1808:
1773:
1767:
1757:
1740:
1736:
1729:
1696:
1692:
1686:
1651:
1647:
1637:
1615:(1): 16–19.
1612:
1608:
1602:
1577:
1574:J. Med. Chem
1573:
1567:
1550:
1545:
1535:
1513:(1): 83–84.
1510:
1506:
1500:
1465:
1461:
1455:
1447:
1430:
1426:
1420:
1412:
1379:
1375:
1369:
1336:
1332:
1326:
1285:
1281:
1275:
1234:
1230:
1224:
1199:
1195:
1185:
1152:
1148:
1142:
1115:
1111:
1101:
1068:
1064:
1058:
1028:(1): 35–92.
1025:
1021:
1015:
995:
975:chromosome 3
968:
967:whereas the
965:chromosome 6
955:
949:
939:
916:
825:barbiturates
808:nor the GABA
768:
765:Pharmacology
749:
718:
710:
698:
686:
657:
608:
540:
524:barbiturates
505:
502:Nomenclature
439:
431:
429:
387:
356:NM_001105580
258:
117:
4694:Compound 14
4524:Lesogaberan
4363:Loreclezole
4300:Loreclezole
4237:(S)-4-ACPCA
4217:Lanthanides
4207:Alphaxolone
4149:Isoguvacine
4059:Terbequinil
3929:apalutamide
3920:Nicardipine
3880:Laudanosine
3687:carbapenems
3679:penicillins
3535:Coriamyrtin
3530:Bicuculline
3519:sevoflurane
3515:paraldehyde
3465:Stiripentol
3342:Niacinamide
3327:cholesterol
3309:Loreclezole
3204:meprobamate
3160:Avermectins
3027:Nefiracetam
2992:Kojic amine
2982:Isomuscimol
2977:Isoguvacine
2095:Ion channel
2025:J Med Genet
885:antagonists
872:Antagonists
814:bicuculline
759:γ2 subunits
650:receptors.
409:Swiss-model
311:Identifiers
280:Swiss-model
170:Identifiers
139:Swiss-model
29:Identifiers
4749:Categories
4549:SKF-97,541
4459:Arbaclofen
4368:Picrotoxin
4358:Bilobalide
4034:Suritozole
4024:Sarmazenil
4009:Ro 19-4603
4004:Ro 15-4513
3999:Radequinil
3966:Picrotoxin
3945:nilutamide
3915:Naltrexone
3850:Furosemide
3830:Flumazenil
3824:oroxylin A
3816:Flavonoids
3796:Etbicyphat
3726:Bilobalide
3693:Basmisanil
3580:Sinomenine
3575:Securinine
3570:Pitrazepin
3555:Hydrastine
3507:chloroform
3480:Topiramate
3420:Propanidid
3284:Imidazoles
3279:Flupirtine
3274:Fluoxetine
3268:hispidulin
3260:Flavonoids
3215:Chloralose
3200:Carbamates
3164:ivermectin
3102:Terpenoids
3047:PF-6372865
2902:Bamaluzole
2869:Ionotropic
2861:modulators
2567:glutamates
2564:Ionotropic
2480:pentamers:
1942:J Med Chem
1693:Vision Res
988:References
946:encoded by
877:Mixed GABA
508:ionotropic
405:Structures
400:Search for
374:Other data
276:Structures
271:Search for
245:Other data
135:Structures
130:Search for
104:Other data
4684:SKF-97541
4679:SCH-50911
4669:Phaclofen
4654:CGP-64213
4649:CGP-55845
4644:CGP-54626
4639:CGP-52432
4634:CGP-46381
4629:CGP-35348
4599:CGP-13501
4574:ADX-71441
4559:Tolgabide
4539:Progabide
4534:Picamilon
4519:Isovaline
4436:Agonists:
4338:-3-ACPBPA
4315:SKF-97541
4265:-3-ACPBPA
4192:Tolgabide
4172:Progabide
4167:Picamilon
4111:Agonists:
4019:RO4938581
4014:RO4882224
3941:flutamide
3875:L-655,708
3845:Flurothyl
3746:Cicutoxin
3731:Bupropion
3698:Bemegride
3675:β-Lactams
3665:Amiloride
3495:Volatiles
3429:etazolate
3405:Phenytoin
3363:zopiclone
3355:abecarnil
3314:Monastrol
3304:Lanthanum
3288:etomidate
3250:Fenamates
3245:Etifoxine
3240:Etazepine
3117:Tolgabide
3067:Progabide
3057:Picamilon
3042:Org 20599
3017:Monastrol
2997:L-838,417
2894:Agonists:
2400:monomers:
2031:(6): E5.
881:-ρ / GABA
654:Structure
619:membranes
484:receptors
452:receptors
327:NCBI gene
227:NM_002043
186:NCBI gene
86:NM_002042
45:NCBI gene
4710:See also
4674:Saclofen
4609:rac-BHFF
4604:GS-39783
4594:CGP-7930
4554:SL 75102
4529:Phenibut
4484:Gabamide
4469:Baclofen
4372:picrotin
4325:SR-95813
4320:SR-95318
4242:2-MeTACA
4154:Muscimol
4084:ZK-93426
4054:TCS-1105
4039:TB-21007
3970:picrotin
3910:Naloxone
3895:Morphine
3890:MaxiPost
3810:fipronil
3806:Fiproles
3776:(+)-DMBB
3771:Dieldrin
3670:Anisatin
3585:SR-42641
3485:Valerian
3459:baicalin
3455:Skullcap
3399:propofol
3379:zaleplon
3371:zolpidem
3264:apigenin
3184:diazepam
3141:Alcohols
3082:SL-75102
3072:Propofol
3052:Phenibut
3022:Muscimol
3006:honokiol
2972:iso-THIP
2967:iso-THAZ
2942:Gabamide
2858:receptor
2711:‘Orphan’
2055:10851258
2006:17981464
1962:10780899
1900:19865977
1892:15998298
1851:15317850
1800:10643085
1749:10635063
1721:14457042
1678:18790874
1629:10637650
1594:10780899
1423:oocytes"
1404:25863134
1361:37167159
1216:11239575
1093:40853254
1050:31732465
1004:Archived
936:Genetics
866:Muscimol
845:Agonists
806:baclofen
773:-ρ from
756:receptor
668:subunits
666:of five
615:chloride
605:Function
565:and GABA
476:receptor
444:receptor
419:InterPro
290:InterPro
149:InterPro
4579:BHF-177
4564:Tolibut
4474:BL-1020
4387:ROD-188
4252:4-ACPAM
4247:3-APMPA
4114:BL-1020
4074:U-93631
4069:Thujone
3994:PWZ-029
3968:(i.e.,
3927:(e.g.,
3905:MRK-016
3885:Lindane
3837:(e.g.,
3818:(e.g.,
3808:(e.g.,
3677:(e.g.,
3655:β-EMGBL
3565:PHP-501
3501:(e.g.,
3472:(e.g.,
3450:ROD-188
3437:(e.g.,
3427:(e.g.,
3412:(e.g.,
3397:(e.g.,
3395:Phenols
3377:(e.g.,
3369:(e.g.,
3361:(e.g.,
3353:(e.g.,
3349:(e.g.,
3321:(e.g.,
3286:(e.g.,
3262:(e.g.,
3252:(e.g.,
3232:(e.g.,
3202:(e.g.,
3190:Bromide
3182:(e.g.,
3172:(e.g.,
3162:(e.g.,
3143:(e.g.,
3136:α-EMTBL
3106:borneol
3104:(e.g.,
3087:Taurine
3034:(e.g.,
3004:(e.g.,
3002:Lignans
2922:BL-1020
2909:(e.g.,
2609:Kainate
2342:Glycine
2046:1734609
1842:6729776
1791:1690471
1713:9667009
1669:2847512
1559:9647870
1527:8386671
1492:8388298
1483:2175610
1456:Xenopus
1439:1314944
1421:Xenopus
1396:9753143
1353:8884747
1318:4320616
1310:8421521
1290:Bibcode
1267:4347233
1259:7678450
1239:Bibcode
1169:6097844
1134:8885697
1085:8638289
1042:1847747
803:agonist
536:retinal
514:of GABA
415:Domains
363:UniProt
286:Domains
260:q14-q21
234:UniProt
145:Domains
119:q14-q21
93:UniProt
4614:KK-92A
4444:3-APPA
4212:ATHDOC
3766:DHEA-S
3605:1,3M1B
3337:Niacin
3298:kavain
2053:
2043:
2004:
1960:
1898:
1890:
1849:
1839:
1798:
1788:
1747:
1719:
1711:
1676:
1666:
1627:
1592:
1557:
1525:
1490:
1480:
1437:
1402:
1394:
1359:
1351:
1316:
1308:
1282:Nature
1265:
1257:
1231:Nature
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1177:966075
1175:
1167:
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970:GABRR3
957:GABRR2
951:GABRR1
712:GABRR3
700:GABRR2
688:GABRR1
587:IUPHAR
496:retina
385:Chr. 3
368:Q9UIV9
351:RefSeq
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320:GABRR3
316:Symbol
256:Chr. 6
239:P28476
222:RefSeq
215:137162
179:GABRR2
175:Symbol
115:Chr. 6
98:P24046
81:RefSeq
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4392:THDOC
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4257:4-GBA
4139:GABOB
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3715:IPTBO
3650:β-CCP
3645:β-CCM
3640:β-CCE
3635:β-CCB
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3499:gases
3331:THDOC
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1896:S2CID
1717:S2CID
1400:S2CID
1357:S2CID
1314:S2CID
1263:S2CID
1173:S2CID
1089:S2CID
1046:S2CID
961:genes
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861:GABOB
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380:Locus
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251:Locus
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4722:GABA
4659:DAVA
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4584:BHFF
4479:GABA
4421:GABA
4397:Zinc
4343:ZAPA
4290:I4AA
4275:DAVA
4182:TAMP
4177:TACA
4134:GABA
4124:CAMP
4119:CACA
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4079:Zinc
4064:TETS
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3791:EBOB
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3761:DHEA
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3149:2M2B
3131:here
3122:ZAPA
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3092:TACA
2937:GABA
2927:DAVA
2879:GABA
2856:GABA
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1958:PMID
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1392:PMID
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