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community. Her achievements throughout her career have earned substantial amounts of attention and credible recognition globally. As the author of an overall encyclopedic of basic virology and clinical manifestations, Human
Herpesviruses, her work has been included in the University of Pennsylvania’s 2007 Celebration of Women Writers. She has gained recent attention for applaudable women in science by the International Society of Antiviral Research (ISAR) that has featured her as a prominent woman scientist. The American Academy of Microbiology awarded recognition of her scientific achievement and her contributions to advanced microbiology. Campadelli’s profound research, leadership principles, scientific achievements, and passion for virology, continue to convey a powerful impression to those within the scientific community. Her influence as a female scientist plays an important role to increasing the status of women in research.
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within scientific fields of work. However, as efforts to increase women's participation in science fields, inequality exists. Furthermore, an underrepresented group of women remain in these fields. Campadelli-Fiume is an influential woman who continues to bridge the gender gap within the scientific
338:
Gabriella
Campadelli-Fiume took part in a study showing that glycoproteins gD, gB, and gH/gL permit herpes virus to enter cells and were involved in fusion. Their research indicated that gD is not required for the interactions between the glycoproteins gB and gH/gL. Rather, their interactions are
329:
Campadelli-Fiume's discovered that nectin is the host cell receptor for HSV. She also discovered the triggering activity of receptor- bound gD. In addition to these major discoveries, she identified the gF profusion domain, which provided the first evidence that retargeted HSVs exert anti-tumor
339:
made possible due to the multiple sites carried by gB. The multiple sites of gB can be found in the pleckstrin-domain that carries the bipartite fusion loop, and interaction with gH/gL can take place successfully without gD.
828:
Eberhardt KE, Thimm BM, Spring A, Maskos WR (1992). "Dose-dependent rate of nosocomial pulmonary infection in mechanically ventilated patients with brain oedema receiving barbiturates: a prospective case study".
919:
Coexpression of UL20p and gK Inhibits Cell-Cell Fusion
Mediated by Herpes Simplex Virus Glycoproteins gD, gH-gL, and Wild-Type gB or an Endocytosis-Defective gB Mutant and Downmodulates Their Cell Surface
901:
Menon PK, Rajagopalan PK (1979). "Seasonal changes in the density and natural mortality of immature stages of the urban malaria vector, Anopheles stephensi (Liston) in wells in
Pondicherry".
514:
Ichikawa K, Hughes IA, Horwitz AL, DeGroot LJ (1987). "Characterization of nuclear thyroid hormone receptors of cultured skin fibroblasts from patients with resistance to thyroid hormone".
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The
Ectodomain of Herpes Simplex Virus Glycoprotein H Contains a Membrane α-Helix with Attributes of an Internal Fusion Peptide, Positionally Conserved in the Herpesviridae Family
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164:(HSV), particularly how it enters, assembles, and exits the cell during an infection. In addition, she is interested in how HSV is induced to enter the exocytic pathway.
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A Herpes
Simplex Virus Recombinant That Exhibits a Single-Chain Antibody to HER2/neu Enters Cells through the Mammary Tumor Receptor, Independently of the gD Receptors
1423:
1180:"Cross Talk among the Glycoproteins Involved in Herpes Simplex Virus Entry and Fusion: the Interaction between gB and gH/gL Does Not Necessarily Require gD"
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The Herpes
Simplex Virus JMP Mutant Enters Receptor-Negative J Cells through a Novel Pathway Independent of the Known Receptors nectin1, HveA, and nectin2
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223:*HSV-1 is the most common infection through the world. It is a lifelong infection with no cure. However, treatment is available to minimize its symptoms
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Construction of a Fully
Retargeted Herpes Simplex Virus 1 Recombinant Capable of Entering Cells Solely via Human Epidermal Growth Factor Receptor 2
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Intracellular
Trafficking and Maturation of Herpes Simplex Virus Type 1 gB and Virus Egress Require Functional Biogenesis of Multivesicular Bodies
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Chen TR (1979). "Cytogenetics of somatic cell hybrids. I. Progression of stemlines in continuous uncloned cultures of man-mouse cell hybrids".
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Entry of Herpes
Simplex Virus Mediated by Chimeric Forms of Nectin1 Retargeted to Endosomes or to Lipid Rafts Occurs through Acidic Endosomes
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Hydrophobic α-Helices 1 and 2 of Herpes Simplex Virus gH Interact with Lipids, and Their Mimetic Peptides Enhance Virus Infection and Fusion
388:(2013–Present) Serves as an editorial board member for the Federation of European Microbiological Societies (FEMS) of Pathogens and Disease
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Herpes Simplex Virus gD Forms Distinct Complexes with Fusion Executors gB and gH/gL in Part through the C-terminal Profusion Domain
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Herpes Simplex Virus gD Forms Distinct Complexes with Fusion Executors gB and gH/gL in Part through the C-terminal Profusion Domain
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Mihalik SJ, Rhead WJ (1991). "Species variation in organellar location and activity of L-pipecolic acid oxidation in mammals".
239:
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Herpes Simplex Virus Glycoproteins gH/gL and gB Bind Toll-Like Receptor 2, and Soluble gH/gL Is Sufficient To Activate NF-κB
1384:
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1408:
472:
468:
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Heptad Repeat 2 in Herpes Simplex Virus 1 gH Interacts with Heptad Repeat 1 and Is Critical for Virus Entry and Fusion
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Zora JA, Lutz CN, Tinkelman DG (1989). "Assessment of compliance in children using inhaled beta adrenergic agonists".
508:
Preclinical therapy of disseminated HER-2+ ovarian and breast carcinomas with a HER-2-retargeted oncolytic herpesvirus
873:
De Castro Barbosa F, Agüera L, Rosell D, Isa W, Sánchez de la Muela P, Robles JE, Bergera JJ, Berián JM (1992). "".
1418:
1324:
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MacLeod SP, MacIntyre DR (1992). "Case report: calcification of genioglossus: a painful radiographic finding".
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Singh GN, Gupta RP, Prakash P (1988). "Effect of ionic strength on the stability of norfloxacin".
253:
854:
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Leonard, Fred (1989). "Butorphanol versus morphine: equally ineffective when given incorrectly".
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Leonard, Fred (1989). "Butorphanol versus morphine: equally ineffective when given incorrectly".
257:
BaltimoreVirusesClassification Classes I-VII (Legend: ss = single stranded; ds = double stranded)
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may contain an excessive amount of intricate detail that may interest only a particular audience
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Chong YH, Soh CC (1966). "The protein nutritive quality of ikan bilis (Stolephorus spp.)".
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AlphaV-beta3-Integrin Relocalizes nectin1 and Routes Herpes Simplex Virus to Lipid Rafts
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Gabriella Campadelli-Fiumme is an active member and leader in the scientific community.
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was also completed at the University of Bologna. Campadelli-Fiume primarily researches
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385:(2005–Present) Serves as an editorial board member for the Journal of Virology
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any relevant information, and removing excessive detail that may be against
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1057:"The way in of HSV: Routing by Integrins and Targeting to Cancer Receptors"
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1385:"Maria Gabriella Campadelli — Università di Bologna — Curriculum vitae"
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Discovered that HSV utilizes gH/gL receptors, αvβ6- and αvβ8-intergins
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Human herpesviruses : biology, therapy and immunoprophylaxis
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Serves on the International Advisory Board for The Lancet Journal
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The Egress of Herpesviruses from Cells: the Unanswered Questions
1350:"78 scientists elected to the American Academy of Microbiology"
447:
1040:"Roberta Fiume — University of Bologna — Curriculum vitae"
216:*Transmitted by oral contact, causes orolabial herpes (
246:. HSV-2 has no cure, as well. It is a lifelong disease
1178:
Avitabile E, Forghieri C, Campadelli-Fiume G (2009).
750:
Ryan LM, Kurup IV, Derfus BA, Kushnaryov VM (1992).
49:
Discovered gD receptor, nectin1 to be HSV's receptor
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Member of Health Research Committee from 2000-2006'
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36:
28:
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375:Fellowship in the American Academy of Microbiology
72:Fellowship in the American Academy of Microbiology
43:Discovered triggers of receptor-bound gD activity
962:Weimann S, Scharfetter H, Riedler L (1979). "".
1354:EurekAlert! The Global Source for Science News
347:Women have made significant progress towards
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1240:from the original on 2017-01-21 – via
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403:Founding Member & Executive Board Member
190:Viral induced alteration of exocytic pathway
32:Doctorate of Science, University of Bologna
1434:Academic staff of the University of Bologna
1329:International Society of Antiviral Research
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249:*Increased risk of acquiring HIV with HSV-2
144:Gabriella Camapadelli-Fiume completed her
18:
1261:. Cambridge: Cambridge University Press.
1203:
1007:
992:"Mutagenicity of radiations at low doses"
767:
495:Learn how and when to remove this message
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1233:Office of Science and Technology Policy
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369:Accademia Nazionale dei Lincei ‘’2002’'
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1307:"WRITERS LIVING BETWEEN 2001 AND 2100"
396:Scientific society and academy founder
1424:21st-century Italian women scientists
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1128:
1126:
7:
334:Additional contributions to virology
176:Varicella-zoster Virus (5614251360)
1009:10.1111/j.1601-5223.1979.tb01649.x
477:Knowledge (XXG)'s inclusion policy
407:European Academy of Microbiology
372:Pasteur Institute, Athens ‘’1997’'
303:Human Herpes simples virus type 1
14:
1158:American Society for Microbiology
112:with a primary research focus on
452:
124:. She is a retired professor of
1439:20th-century Italian scientists
990:Hussain S, Ehrenberg L (1979).
752:"ATP-induced chondrocalcinosis"
156:, Italy. Her specialization in
68:Accademia Nazionale dei Lincei
1311:A Celebration of Women Writers
401:European Society for Virology
240:Sexually transmitted infection
1:
1444:20th-century women scientists
806:10.1016/s0009-9260(05)80322-8
684:10.1016/s0196-0644(89)80869-8
620:10.1016/s0196-0644(89)80869-8
1429:University of Bologna alumni
1154:"Gabriella Campadelli Fiume"
528:10.1016/0026-0495(87)90214-9
413:Italian Society of Virology
1255:Arvin, Ann M., ed. (2007).
1465:
1449:20th-century Italian women
1106:"Faculty Member's Website"
432:Italian Ministry of Health
106:Gabriella Campadelli-Fiume
70:Pasteur Institute, Athens
23:Gabriella Campadelli-Fiume
1140:World Health Organization
426:European Research Council
99:
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429:DGXII Health Commissions
286:Baltimore Classification
187:HSV exit out of the cell
1325:"Women in Science 2015"
202:consists of two types:
181:HSV entry into the cell
1136:"Herpes simplex virus"
769:10.1002/art.1780351216
258:
230:Herpes simplex virus 2
208:Herpes simplex virus 1
184:Viral assembly in cell
177:
140:Education and research
87:Microbiology, Virology
1389:University of Bologna
1110:Universita Di Bologna
1061:Herpes Virus Workshop
928:Cytogenet. Cell Genet
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175:
154:University of Bologna
130:University of Bologna
95:University of Bologna
1196:10.1128/JVI.01287-09
220:) and genital herpes
200:Herpes simplex virus
195:Herpes simplex virus
162:Herpes simplex virus
146:doctorate of science
114:herpes simplex virus
1409:Italian virologists
1190:(20): 10752–10760.
1184:Journal of Virology
905:. 70 Suppl: 123–7.
708:J. Comp. Physiol. B
903:Indian J. Med. Res
843:10.1007/bf01704886
720:10.1007/bf00571266
444:Major publications
380:Editorial activity
317:Alphaherpesvirinae
259:
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16:Italian virologist
1419:Women virologists
1268:978-0-511-29013-8
1242:National Archives
940:10.1159/000131332
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421:Committee service
325:Major discoveries
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242:, can also cause
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78:Scientific career
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516:Metab. Clin. Exp
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1067:on May 20, 2015
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467:Please help by
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409:Founding Member
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964:Zentralbl Chir
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877:(in Spanish).
875:Actas Urol Esp
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1065:the original
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1002:(1): 111–5.
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714:(6): 671–6.
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611:
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583:
580:Med J Malaya
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316:
311:
308:
299:Simplexvirus
298:
295:
285:
279:Herpesvirdae
278:
273:
263:
228:
206:
198:
143:
105:
104:
92:Institutions
77:
69:
837:(1): 12–8.
794:Clin Radiol
644:Ann Allergy
122:viral entry
1403:Categories
1277:2008270060
1026:References
920:Expression
558:(2): 134.
485:April 2020
473:relocating
356:Leadership
330:activity.
218:cold sores
110:virologist
1285:174563578
1115:April 29,
1071:April 29,
996:Hereditas
831:Infection
552:Pharmazie
343:Influence
312:Subfamily
152:) at the
128:from the
29:Education
1293:9463135M
1238:Archived
1214:19656900
736:35457957
349:equality
290:Group I
210:(HSV-1)
158:virology
126:virology
57:Children
1205:2753139
887:1488928
859:1210701
851:1563806
814:1395405
778:1472129
728:2045546
692:2719377
656:2566291
628:2719377
592:4223072
564:3393584
536:3561254
232:(HSV-2)
1291:
1283:
1275:
1265:
1212:
1202:
1163:19 May
1018:387673
1016:
976:525084
974:
948:446093
946:
911:548475
909:
885:
857:
849:
812:
776:
734:
726:
690:
654:
626:
590:
562:
534:
364:Awards
274:Family
118:fusion
84:Fields
65:Awards
855:S2CID
732:S2CID
309:Genus
296:Genus
150:Sc.D.
134:Italy
108:is a
1281:OCLC
1273:LCCN
1263:ISBN
1210:PMID
1165:2015
1117:2015
1073:2015
1014:PMID
972:PMID
944:PMID
907:PMID
883:PMID
847:PMID
810:PMID
774:PMID
724:PMID
688:PMID
652:PMID
624:PMID
588:PMID
560:PMID
532:PMID
120:and
1200:PMC
1192:doi
1004:doi
968:104
936:doi
839:doi
802:doi
764:doi
716:doi
712:160
680:doi
616:doi
524:doi
471:or
132:,
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