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Consumer magazine said: "No health claims for
Gerovital have been substantiated, and FDA considers it an unapproved new drug. It has caused low blood pressure, respiratory difficulties, and convulsions in some users." Suppliers assert that the product is safe, and one cites a brief quotation from a
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have been listed among the multitudes said to have taken the drug." As late as 1988 an advertisement by the
Romanian National Tourist Office lauded "the picturesque and exciting cities, scenic delights, famous resorts (including Gerovital H3 treatment centers), cultural and historic treasures that
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and products known as GH3 and other variants which may or may not be identical to
Gerovital H3) is a preparation developed during the 1950s and promoted by its advocates as an effective anti-aging treatment. In the United States, the FDA bans Gerovital H3 from interstate commerce as an unapproved
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Procaine itself is often considered to be a drug. Earlier references by advocates of
Gerovital H3 refer to it as a drug. Hoffer and Walker (1980) call it a "youth drug". Mircea Dumitru, Aslan's colleague and personal physician, describes it as "a complex drug acting like the procaine
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From the 1950s until her death in 1988, Aslan promoted
Gerovital H3 with great success. In the 1960s and 1970s her Romanian clinic, the Parhon Institute, became a mecca for celebrities seeking treatment, and an upscale tourist attraction.
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article said "cold water was thrown on 's reputation years ago" by "three reports published simultaneously in
British Medical Journal found no merit for procaine hydrochloride for any of the problems of aging."
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As of 2004, the FDA's 1982 automatic detention alert is still in effect and bans the import of
Gerovital H3 into the U.S. as "a new drug within the meaning of 201(p), without an approved new drug application ."
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Gerovital is promoted with unsupported claims of its curative abilities for a wide range of human ailments; research has found no evidence that it has any health benefit or "anti-aging" properties.
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newspaper article that says "while as early as 1973 Elmer
Gardner of the FDA's Bureau of Drugs stated 'There is no safety problem with Gerovital H-3.
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molecule ... The addition of benzoic acid, potassium and disodium phosphate increase the effects of
Gerovital-H3 biotrophic treatment."
50:, who is also wrongly claimed to have funded the establishment of a research organization, the National Institute of Geriatrics, in
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Gerovital has enjoyed a new lease of promotional life as it is promoted by many sites with claims of its "cure-all" abilities.
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referred to
Gerovital's "jet-set aura", noting that Aslan had been covered in "society columns where such public figures as
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Gerovital, GH3, KH3, Zell H3, GH3 etc. This order was rescinded for GEROVITAL Cosmetics Lines, not containing procaine.
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Some clinical trials in the mid-to-late 1970s suggested that Gerovital H3 acts as a weak, competitive, reversible
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108:, and so may have some antidepressant value, but otherwise has a negligible effect on disease. In 1994, the U.S.
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Harold M. Schmeck Jr (1973-03-18). "Disputed Drug Is Restudied for Use in Geriatrics".
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There is no evidence that Gerovital is helpful in slowing aging or treating illness.
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303:"Professor Ana Aslan and Gerovital-H3, the Original and First Anti-Aging Medicine"
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51:
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The impetus for developing the drug is sometimes alleged to have come from
180:"The reappearance of procaine hydrochloride (Gerovital H3) for antiaging"
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196:
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328:"Automatic Detention [for Gerovital] (IA#61-01)"
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drug and, since 1982, has prohibited its importation.
330:. U.S. Food and Drug Administration. Archived from
153:finished injectable or oral Procaine Hydrochloride
305:. International Antiaging Systems. Archived from
227:"Our colorful TOUROMANIA booklet has it all".
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259:"Unproven Medical Treatments Lure Elderly"
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279:. Tierra Mega-Nutrients. Archived from
261:. FDA Consumer Magazine. Archived from
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16:Pseudoscientific anti-aging treatment
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23:Original presentation of Gerovital
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79:await the traveler to Romania."
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301:Dumitru M.D. Ph. D., Mircea.
257:Jed Disbennett (March 1994).
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42:Development and marketing
32:procaine hydrochloride
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384:Anti-aging substances
369:Health fraud products
178:Perls T (June 2013).
82:With the rise of the
54:, Romania, headed by
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364:Alternative medicine
68:Nikita S. Khrushchev
389:Romanian inventions
58:(1897–1988).
64:The New York Times
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197:10.1111/jgs.12278
129:Drug or nutrient?
48:Nicolae Ceaușescu
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379:Patent medicines
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184:J Am Geriatr Soc
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374:Withdrawn drugs
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72:Konrad Adenauer
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265:on 2004-12-11.
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190:(6): 1024–5.
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121:Effectiveness
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336:. Retrieved
332:the original
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311:. Retrieved
307:the original
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285:. Retrieved
281:the original
277:"FDA Quotes"
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263:the original
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90:Denouncement
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28:Gerovital H3
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353:Categories
338:2006-11-28
313:2006-12-02
287:2006-11-28
158:References
56:Ana Aslan
52:Bucharest
214:41813351
206:23772727
76:Ibn Saud
138:FDA ban
94:A 1973
359:Ageing
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74:, and
210:S2CID
202:PMID
30:(or
192:doi
110:FDA
84:Web
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