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Hypnogram

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On a hypnogram, a sleep cycle is usually around 90 minutes and there are four to six cycles of REM/NREM stages that occur during a major period of sleep. Most SWS occurs in the first one or two cycles; this is the deepest period of sleep. The second half of the sleeping period contains most REM sleep
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The method of obtaining the data used in a hypnogram is restricted to the input from an EEG, EOG or EMG. The interval of recording may include features from several stages, in which case it is recorded as the stage whose features occupy the recording for the longest duration. For this reason, the
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The restrictions of measuring sleep at short 30-second epochs limits the ability to record events shorter than 30 seconds; hence, the macrostructure of sleep can be evaluated while the microstructure is not. The sleep process is smoothened out in hypnogram results unlike it occurs naturally. Also
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Cycles of REM and non-REM stages make up sleep. A normal healthy adult requires 7–9 hours of sleep per night. The number of hours of sleep is variable, however the proportion of sleep spent in a particular stage remains mostly consistent; healthy adults normally spend 20–25% of their sleep in REM
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The output from these three sources is recorded simultaneously on a graph by a monitor or computer as a hypnogram. Certain frequencies displayed by EEGs, EOGs and EMGs are characteristic and determine what stage of sleep or wake the subject is in. There is a protocol defined by the
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can be evaluated using hypnograms, demonstrating irregular sleeping patterns associated with sleep disorders. Disruptions or irregularities to the normal sleep cycle or sleep stage transitions can be detected; for example a hypnogram can show that in
53:(NREM) to be identified during the sleep cycle. NREM sleep can be further classified into NREM stage 1, 2 and 3. The previously considered 4th stage of NREM sleep has been included within stage 3; this stage is also called 197:
Suggestions to improve the automated output of hypnograms to provide more reliable and accurate results include increasing the measures of sleep, for example by additionally measuring sleep with an
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Danker-Hopfe H, Anderer P, Zeitlhofer J, et al. (March 2009). "Interrater reliability for sleep scoring according to the Rechtschaffen & Kales and the new AASM standard".
93:(AASM) for sleep scoring, whereby the sleep or wake state is recorded in 30-second epochs. Prior to this the Rechtschaffen and Kales (RK) rules were used to classify sleep stages. 770:
Pracki T, Pracka D, Ziółkowska-Kochan M, Tafll-Klawe M, Szota A, Wiłkość M (2008). "The modified Color Density Spectral Array--an alternative method for sleep presentation".
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Ferrara M, De Gennaro L, Casagrande M, Bertini M (July 2000). "Selective slow-wave sleep deprivation and time-of-night effects on cognitive performance upon awakening".
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sleep. During rest following a sleep-deprived state, there is a period of rebound sleep which has longer and deeper episodes of SWS to make up for the lack of sleep.
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Merica H, Fortune RD (December 2004). "State transitions between wake and sleep, and within the ultradian cycle, with focus on the link to neuronal activity".
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method to visualise the time period of each stage of sleep, as well as the number of transitions between stages. Hypnograms are rarely used to provide
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Barcaro U, Navona C, Belloli S, Bonanni E, Gneri C, Murri L (May 1998). "A simple method for the quantitative description of sleep microstructure".
333: 469: 409: 201:(ECG). Another advancement involves combining hypnograms with color density spectral arrays to improve the quality of sleep analysis. 90: 144:(PHT) can be seen to disrupt sleep by increasing the duration of NREM stage 1 and decreasing the duration of SWS; whereas the drug 318:
2001 Conference Proceedings of the 23rd Annual International Conference of the IEEE Engineering in Medicine and Biology Society
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data, however it has been suggested that statistical evaluation can be carried out using multistate survival analysis and
157: 261:"Modulation of the Sympatho-Vagal Balance during Sleep: Frequency Domain Study of Heart Rate Variability and Respiration" 50: 735:
Krakovská A, Mezeiová K (September 2011). "Automatic sleep scoring: a search for an optimal combination of measures".
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as a function of time. It was developed as an easy way to present the recordings of the brain wave activity from an
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which can be recorded but are not usually perceived. The stage that occurs before waking is normally REM sleep.
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The effects of certain medications on sleep architecture can be visualised on a hypnogram. For example, the
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Hypnograms for healthy persons vary slightly according to age, emotional state, and environmental factors.
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Legros B, Bazil CW (January 2003). "Effects of antiepileptic drugs on sleep architecture: a pilot study".
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may not be defined in the hypnogram; this is particularly true for sleep scoring that is automated.
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Silber MH, Ancoli-Israel S, Bonnet MH, Chokroverty S, Grigg-Damberger MM, et al. (2007).
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Here, both stage 3 and stage 4 are shown; these are often combined as stage 3.
279: 141: 134:(OSA) the stability of transition between REM and NREM stages is disrupted. 785: 756: 686: 633: 598: 506: 446: 378: 298: 245: 721: 45:(EEG) during a period of sleep. It allows the different stages of sleep: 73:
Hypnograms are usually obtained by visually scoring the recordings from
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Cabiddu R, Cerutti S, Viardot G, Werner S, Bianchi AM (2012).
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is seen to revive sleep by increasing the duration of SWS.
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Bianchi MT, Cash SS, Mietus J, Peng CK, Thomas R (2010).
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stage of sleep may be misrepresented on the hypnogram.
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and little or no SWS and may contain brief periods of
653:"Characterizing sleep structure using the hypnogram" 314:"BioSleep: A comprehensive sleep analysis system" 312:McGrogan N, Braithwaite E, Tarassenko L (2001). 8: 23:Example hypnogram of a normal, healthy adult 69:A hypnogram (top) with other readings below 676: 588: 578: 537: 288: 278: 235: 57:(SWS) and is the deepest stage of sleep. 522:"Treatment of sleep disorders in adults" 177:some specific features of sleep such as 220:"The visual scoring of sleep in adults" 210: 7: 702:Electroencephalogr Clin Neurophysiol 156:The main use of a hypnogram is as a 37:; it is a graph that represents the 168:to provide numerical significance. 803:American Academy of Sleep Medicine 224:Journal of Clinical Sleep Medicine 91:American Academy of Sleep Medicine 14: 526:Advances in Psychiatric Treatment 464:. Wiley-Blackwell. pp. 2–3. 320:. Vol. 2. pp. 1608–11. 371:10.1111/j.1365-2869.2008.00700.x 404:. Wiley-Blackwell. p. 2. 1: 808:National Institutes of Health 714:10.1016/S0013-4694(98)00008-X 626:10.1016/s1389-9457(02)00217-4 749:10.1016/j.artmed.2011.06.004 651:, Punjabi NM (August 2008). 580:10.1371/journal.pone.0011356 51:non-rapid eye movement sleep 839: 499:10.1016/j.smrv.2004.06.006 326:10.1109/IEMBS.2001.1020520 520:Wilson S, Nutt D (1999). 462:Sleep Medicine Essentials 439:10.1111/1469-8986.3740440 402:Sleep Medicine Essentials 359:Journal of Sleep Research 16:Graph of a person's sleep 280:10.3389/fphys.2012.00045 47:rapid eye movement sleep 132:obstructive sleep apnea 460:Lee-Chiong TL (2009). 400:Lee-Chiong TL (2009). 70: 26: 647:Swihart BJ, Caffo B, 68: 22: 75:electroencephalogram 43:electroencephalogram 571:2010PLoSO...511356B 193:Research directions 773:Acta Neurobiol Exp 669:10.5664/jcsm.27236 539:10.1192/apt.5.1.11 237:10.5664/jcsm.26814 127:Sleep architecture 79:electrooculography 71: 27: 335:978-0-7803-7211-5 199:electrocardiogram 166:log-linear models 830: 790: 789: 767: 761: 760: 737:Artif Intell Med 732: 726: 725: 697: 691: 690: 680: 657:J Clin Sleep Med 644: 638: 637: 609: 603: 602: 592: 582: 550: 544: 543: 541: 517: 511: 510: 482: 476: 475: 457: 451: 450: 427:Psychophysiology 422: 416: 415: 397: 391: 390: 354: 348: 347: 309: 303: 302: 292: 282: 256: 250: 249: 239: 215: 83:electromyography 838: 837: 833: 832: 831: 829: 828: 827: 813: 812: 799: 794: 793: 769: 768: 764: 734: 733: 729: 699: 698: 694: 649:Bandeen-Roche K 646: 645: 641: 611: 610: 606: 552: 551: 547: 519: 518: 514: 484: 483: 479: 472: 459: 458: 454: 424: 423: 419: 412: 399: 398: 394: 356: 355: 351: 336: 311: 310: 306: 258: 257: 253: 217: 216: 212: 207: 195: 174: 154: 124: 122:Disrupted sleep 104: 99: 63: 55:slow wave sleep 39:stages of sleep 35:polysomnography 24: 17: 12: 11: 5: 836: 834: 826: 825: 823:Sleep medicine 815: 814: 811: 810: 805: 798: 797:External links 795: 792: 791: 762: 727: 692: 639: 604: 545: 512: 477: 471:978-0470195666 470: 452: 417: 411:978-0470195666 410: 392: 349: 334: 304: 251: 209: 208: 206: 203: 194: 191: 179:sleep spindles 173: 170: 153: 150: 139:anticonvulsant 123: 120: 103: 100: 98: 95: 62: 59: 15: 13: 10: 9: 6: 4: 3: 2: 835: 824: 821: 820: 818: 809: 806: 804: 801: 800: 796: 787: 783: 779: 775: 774: 766: 763: 758: 754: 750: 746: 742: 738: 731: 728: 723: 719: 715: 711: 708:(5): 429–32. 707: 703: 696: 693: 688: 684: 679: 674: 670: 666: 663:(4): 349–55. 662: 658: 654: 650: 643: 640: 635: 631: 627: 623: 619: 615: 608: 605: 600: 596: 591: 586: 581: 576: 572: 568: 565:(6): e11356. 564: 560: 556: 549: 546: 540: 535: 531: 527: 523: 516: 513: 508: 504: 500: 496: 493:(6): 473–85. 492: 488: 487:Sleep Med Rev 481: 478: 473: 467: 463: 456: 453: 448: 444: 440: 436: 432: 428: 421: 418: 413: 407: 403: 396: 393: 388: 384: 380: 376: 372: 368: 364: 360: 353: 350: 345: 341: 337: 331: 327: 323: 319: 315: 308: 305: 300: 296: 291: 286: 281: 276: 272: 268: 267: 266:Front Physiol 262: 255: 252: 247: 243: 238: 233: 230:(2): 121–31. 229: 225: 221: 214: 211: 204: 202: 200: 192: 190: 186: 184: 180: 171: 169: 167: 163: 159: 151: 149: 147: 143: 140: 135: 133: 128: 121: 119: 116: 114: 108: 101: 96: 94: 92: 86: 84: 80: 76: 67: 60: 58: 56: 52: 48: 44: 40: 36: 33:is a form of 32: 21: 780:(4): 516–8. 777: 771: 765: 743:(1): 25–33. 740: 736: 730: 705: 701: 695: 660: 656: 642: 617: 613: 607: 562: 558: 548: 529: 525: 515: 490: 486: 480: 461: 455: 433:(4): 440–6. 430: 426: 420: 401: 395: 365:(1): 74–84. 362: 358: 352: 317: 307: 270: 264: 254: 227: 223: 213: 196: 187: 175: 162:quantitative 155: 136: 125: 117: 109: 105: 102:Normal sleep 87: 72: 30: 28: 620:(1): 51–5. 183:K complexes 172:Limitations 158:qualitative 113:wakefulness 81:(EOGs) and 205:References 146:Gabapentin 49:(REM) and 614:Sleep Med 532:: 11–18. 142:Phenytoin 31:hypnogram 817:Category 786:19112475 757:21742473 687:18763427 634:14592360 599:20596541 559:PLOS ONE 507:15556379 447:10934902 387:38993280 379:19250176 299:22416233 246:17557422 152:Analysis 85:(EMGs). 77:(EEGs), 722:9680156 678:2542492 590:2893208 567:Bibcode 344:2966203 290:3299415 784:  755:  720:  685:  675:  632:  597:  587:  505:  468:  445:  408:  385:  377:  342:  332:  297:  287:  273:: 45. 244:  97:Output 61:Method 383:S2CID 340:S2CID 782:PMID 753:PMID 718:PMID 683:PMID 630:PMID 595:PMID 503:PMID 466:ISBN 443:PMID 406:ISBN 375:PMID 330:ISBN 295:PMID 242:PMID 181:and 745:doi 710:doi 706:106 673:PMC 665:doi 622:doi 585:PMC 575:doi 534:doi 495:doi 435:doi 367:doi 322:doi 285:PMC 275:doi 232:doi 819:: 778:68 776:. 751:. 741:53 739:. 716:. 704:. 681:. 671:. 659:. 655:. 628:. 616:. 593:. 583:. 573:. 561:. 557:. 528:. 524:. 501:. 489:. 441:. 431:37 429:. 381:. 373:. 363:18 361:. 338:. 328:. 316:. 293:. 283:. 269:. 263:. 240:. 226:. 222:. 29:A 788:. 759:. 747:: 724:. 712:: 689:. 667:: 661:4 636:. 624:: 618:4 601:. 577:: 569:: 563:5 542:. 536:: 530:5 509:. 497:: 491:8 474:. 449:. 437:: 414:. 389:. 369:: 346:. 324:: 301:. 277:: 271:3 248:. 234:: 228:3

Index

Example hypnogram for a normal, healthy adult. Within the first hour of sleep SWS is displayed. Cycles of REM and NREM sleep proceed. During the third cycle of sleep there are two brief wake states. During the second half of the sleep period more REM sleep is displayed and there is little SWS detected.
polysomnography
stages of sleep
electroencephalogram
rapid eye movement sleep
non-rapid eye movement sleep
slow wave sleep

electroencephalogram
electrooculography
electromyography
American Academy of Sleep Medicine
wakefulness
Sleep architecture
obstructive sleep apnea
anticonvulsant
Phenytoin
Gabapentin
qualitative
quantitative
log-linear models
sleep spindles
K complexes
electrocardiogram
"The visual scoring of sleep in adults"
doi
10.5664/jcsm.26814
PMID
17557422
"Modulation of the Sympatho-Vagal Balance during Sleep: Frequency Domain Study of Heart Rate Variability and Respiration"

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