Knowledge (XXG)

Haim Aviv

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He chaired and was a member of the Israel National Committee for Biotechnology and other advisory committees on this subject. Among his major recommendations was the establishment of dedicated investment funds with the aid of government funding, a recommendation which is currently being implemented
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did not meet expectations. The lack of success in the trials provoked a negative response from the company's investors and the Israeli media. Aviv left his position at Pharmos in 2007. However, these clinical trials remain to this day the largest trials performed in the field of pharmaceutical
365:, which are based on scientific research and clinical evidence. The products are marketed as snack bars and beverages under the brand Nutravida. The Functional Food segment is a rapidly growing field, which is expected to have a fundamental effect on population well-being. 299:
In 1980, Aviv initiated and started "Biotechnology General Corp.", the first Israeli Biotechnology company focusing on Recombinant DNA (genetic engineering), which exists to this day. The foundation of the company was encouraged by
287:. The patented method he developed is used for the industrial production of growth hormone, in order to increase milk production by cows. Bovine growth hormone is in wide use in today's 570: 357:
As of 2011, Aviv focused his work in the company "Herbamed Ltd.", as chairman and major shareholder. Herbamed is an Israeli company which develops health-supporting food products (
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In 2000, Aviv founded "Predix Corp.", which focused on development of pharmaceuticals using advanced computerization and three-dimensional algorithms, invented by Dr. Oren Becker.
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Other than his position at Herbamed, Aviv also serves on the board of directors of Yeda Research and Development Company Ltd., which is the commercial arm of the
190:'s lab. In 1973 he returned to Israel, to the Weizmann Institute of Science, as a senior scientist and was then appointed associate professor with tenure. 580: 304:, formerly the president of Israel, and was supported by a group of investors led by Mr. Fred Adler, one of the leading Venture Capitalists. 166:, and planned a future in this field, almost with no connection to science. After completing an M.Sc. in The Faculty of Agriculture at the 373: 229:. This work was published in a series of papers, some of which were of the most quoted in the field of molecular biology for decades. 324: 167: 565: 369: 214: 183: 171: 103: 560: 174:
in Rehovot. At first Aviv was interested in the study of plant biology, but he soon found himself fascinated with
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mechanisms. After his return to Israel, he continued to study the field of mRNA differentiation and synthesis.
253: 424:"Purification of biologically active globin messenger RNA by chromatography on oligothymidylic acid-cellulose" 343: 162:, where he resided until his death in 2021. In his early twenties, he developed an interest in the field of 89: 217:, Aviv focused on the research of molecular processes related to differentiation, and synthesis control of 585: 347: 575: 237: 590: 494: 435: 307:
After he retired from "Biotechnology General Ltd.", Aviv founded "Diatech Ltd." which specialized in
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treatment of head injury. Serious traumatic head injuries remain to this day a medical challenge.
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An editorial on the subject of "Bridging the Gap between Food and Health" written by Aviv in 2010
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tools, and "Pharmos Corp."- In which he served as chairman and CEO. Pharmos initially focused on
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industry in Israel, as he was widely involved in this industry since the late 1970s to this day.
319:), but was mostly known for its later work to develop an innovative drug invented by Professor 522: 463: 381: 320: 308: 261: 179: 175: 131: 77: 512: 502: 453: 443: 377: 312: 81: 397: 358: 272: 257: 119: 93: 498: 439: 301: 288: 222: 198: 517: 482: 458: 423: 554: 362: 233: 202: 151: 135: 85: 332: 265: 226: 187: 540: 336: 328: 163: 487:
Proceedings of the National Academy of Sciences of the United States of America
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Proceedings of the National Academy of Sciences of the United States of America
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with the foundation of two large-scale funds which include government aid.
526: 507: 467: 483:"In vitro synthesis of DNA complementary to purified rabbit globin mRNA" 260:'s lab he performed research which first made it possible to synthesize 316: 280: 245: 194: 159: 147: 49: 35: 134:. Aviv is considered to have a fundamental role in the shaping of the 218: 155: 60: 264:(cDNA), a method which was later widely used in the research of 249: 241: 402: 236:(mRNA) which enabled research of control mechanisms of the 126:) (born as Haim Greenspan in Romania, 1940) was an Israeli 178:. In 1970 Aviv completed his doctorate, which focused on 541:"Production of bovine growth hormone by microorganisms" 279:) and applied research, and produced a microorganism ( 481:
Ross J, Aviv H, Scolnick E, Leder P (January 1972).
182:, and was offered a postdoctoral fellowship at the 99: 73: 56: 42: 28: 21: 271:During the late 1970s, Aviv entered the field of 232:Aviv developed a method for the purification of 158:at the age of ten. He was raised in the city of 571:Businesspeople in the pharmaceutical industry 295:Advancement of Israeli biotechnology industry 8: 205:. He also collected ancient Judaica books. 18: 516: 506: 457: 447: 376:and at several companies in the field of 170:, he began his doctorate studies in the 414: 7: 123: 374:Ben-Gurion University of the Negev 315:for the treatment of Eye disease ( 14: 256:and tissues. In cooperation with 193:In his spare time, Aviv studied 130:who specialized in the field of 422:Aviv H.; Leder P. (June 1972). 325:Hebrew University of Jerusalem 168:Hebrew University of Jerusalem 1: 370:Weizmann Institute of Science 342:Despite promising results in 184:National Institutes of Health 172:Weizmann Institute of Science 104:Weizmann Institute of Science 581:Romanian emigrants to Israel 225:, under the guidance of Dr. 403:Website of Herbamed Company 154:) in 1940, and migrated to 607: 283:) containing the gene for 248:, and studied the role of 109: 66: 254:differentiation of cells 348:phase 3 clinical trials 344:Phase 2 clinical trials 90:Pharmaceutical industry 449:10.1073/pnas.69.6.1408 508:10.1073/pnas.69.1.264 285:Bovine Growth Hormone 186:(NIH) in the US, Dr. 566:Molecular biologists 313:development of drugs 499:1972PNAS...69..264R 440:1972PNAS...69.1408A 277:genetic engineering 213:During his work in 142:Birth and education 561:Israeli scientists 346:, the large scale 309:medical diagnostic 321:Raphael Mechoulam 262:complementary DNA 180:protein synthesis 176:molecular biology 146:Aviv was born in 132:molecular biology 113: 112: 78:Molecular Biology 68:Scientific career 16:Israeli scientist 598: 545: 544: 537: 531: 530: 520: 510: 478: 472: 471: 461: 451: 419: 378:drug development 359:Functional Foods 201:, especially of 125: 82:Drug development 19: 606: 605: 601: 600: 599: 597: 596: 595: 551: 550: 549: 548: 539: 538: 534: 480: 479: 475: 421: 420: 416: 411: 394: 382:medical devices 331:), a synthetic 297: 273:Recombinant DNA 258:Edward Scolnick 223:Immunoglobulins 211: 144: 94:Functional food 52: 47: 38: 33: 24: 17: 12: 11: 5: 604: 602: 594: 593: 588: 583: 578: 573: 568: 563: 553: 552: 547: 546: 532: 473: 434:(6): 1408–12. 413: 412: 410: 407: 406: 405: 400: 393: 392:External links 390: 363:Nutraceuticals 302:Ephraim Katzir 296: 293: 289:dairy industry 210: 207: 199:Jewish history 143: 140: 111: 110: 107: 106: 101: 97: 96: 75: 71: 70: 64: 63: 58: 54: 53: 48: 44: 40: 39: 34: 30: 26: 25: 22: 15: 13: 10: 9: 6: 4: 3: 2: 603: 592: 589: 587: 586:Living people 584: 582: 579: 577: 574: 572: 569: 567: 564: 562: 559: 558: 556: 542: 536: 533: 528: 524: 519: 514: 509: 504: 500: 496: 492: 488: 484: 477: 474: 469: 465: 460: 455: 450: 445: 441: 437: 433: 429: 425: 418: 415: 408: 404: 401: 399: 396: 395: 391: 389: 385: 383: 379: 375: 371: 366: 364: 360: 355: 352: 349: 345: 340: 338: 334: 330: 326: 322: 318: 314: 310: 305: 303: 294: 292: 290: 286: 282: 278: 274: 269: 267: 263: 259: 255: 251: 247: 243: 239: 235: 234:messenger RNA 230: 228: 224: 220: 216: 209:Academic work 208: 206: 204: 203:The Holocaust 200: 196: 191: 189: 185: 181: 177: 173: 169: 165: 161: 157: 153: 149: 141: 139: 137: 136:biotechnology 133: 129: 121: 117: 108: 105: 102: 98: 95: 91: 87: 86:Biotechnology 83: 79: 76: 72: 69: 65: 62: 59: 55: 51: 45: 41: 37: 31: 27: 20: 576:Israeli Jews 535: 493:(1): 264–8. 490: 486: 476: 431: 427: 417: 386: 367: 356: 353: 341: 306: 298: 270: 266:gene control 231: 227:Philip Leder 212: 192: 188:Philip Leder 145: 115: 114: 100:Institutions 67: 591:1940 births 337:head injury 329:Dexanabinol 238:translation 164:agriculture 57:Citizenship 555:Categories 409:References 333:canabinoid 339:victims. 335:to treat 323:from the 128:scientist 124:חיים אביב 116:Haim Aviv 23:Haim Aviv 527:4333043 495:Bibcode 468:4504350 436:Bibcode 317:Lotemax 281:E. coli 252:in the 246:protein 219:Globins 195:Judaism 160:Rehovot 148:Romania 50:Rehovot 36:Romania 525:  518:427588 515:  466:  459:426713 456:  372:, The 361:) and 156:Israel 120:Hebrew 74:Fields 61:Israel 523:PMID 464:PMID 380:and 250:mRNA 221:and 197:and 152:Arad 46:2021 43:Died 32:1940 29:Born 513:PMC 503:doi 454:PMC 444:doi 244:to 242:RNA 240:of 215:NIH 557:: 521:. 511:. 501:. 491:69 489:. 485:. 462:. 452:. 442:. 432:69 430:. 426:. 384:. 291:. 122:: 92:, 88:, 84:, 80:, 543:. 529:. 505:: 497:: 470:. 446:: 438:: 327:( 275:( 150:( 118:(

Index

Romania
Rehovot
Israel
Molecular Biology
Drug development
Biotechnology
Pharmaceutical industry
Functional food
Weizmann Institute of Science
Hebrew
scientist
molecular biology
biotechnology
Romania
Arad
Israel
Rehovot
agriculture
Hebrew University of Jerusalem
Weizmann Institute of Science
molecular biology
protein synthesis
National Institutes of Health
Philip Leder
Judaism
Jewish history
The Holocaust
NIH
Globins
Immunoglobulins

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