479:
were raided by Korean regulatory authorities in mid-October based on evidence that insider knowledge of the
Boehringer termination was passed to third parties, who shorted the stock prior to the announcement on the 30th. In December three Hanmi employees were among 17 people indicted for insider trading; 25 people were fined, and 45 people were found to have made illegal trades that took around 3.3 billion won ($ 2.83 million) in profits based on the information.
1101:
27:
478:
On the evening of
September 29, 2016, Hanmi announced the Roche deal, causing its stock to rise; Hanmi was notified by Boehringer that evening that Boehringer was terminating their deal, and the company announced the termination on the morning of the 30th, causing its stock to crash. Hanmi's offices
409:
province of China, where it would build a manufacturing plant and R&D facility; at that time it already had a facility in
Beijing. In July Hanmi said it intended to invest more heavily in developing candidate substances of promising new drugs at an early stage in new pharmaceutical and biotech
498:
In April 2018 Hanmi was found to have violated two laws in Korea by not disclosing adverse effects of olmutinib sooner. In that month Zai said it was dropping olmutinib and a few days later Hanmi said it was terminating development of the drug.
450:
In
December 2016 the Sanofi deal was reduced in scope, with Hanmi receiving back rights to the once-weekly insulin and the combination GLP1-RA/insulin product, and agreeing to repay Sanofi $ 250 million of the $ 434 million upfront payment.
454:
On
December 3, 2019, Rapt Therapeutics and Hanami Pharmaceutical announced collaboration to develop and commercialize FLX475 in Asia. FLX475 is an oral, small molecule CCR4 antagonist in development for the treatment of multiple cancers.
495:; Boeheringer announced the termination its deal with Hanmi the same day, citing that the decision came after a review of "all available clinical data" on the drug, and also referring to competing drugs.
2041:
2036:
637:
2031:
794:
371:, a long-acting glucagon-like peptide-1 receptor agonist; an insulin intended to be delivered once per week, and a fixed-dosed weekly GLP1-RA/insulin drug combination.
2051:
2026:
868:
927:
337:, to the Chinese company Luye Pharma; in February 2015 Hanmi licensed rights in the rest of the world outside of South Korea to Spectrum Pharmaceuticals.
718:
282:
100,000,000,000 barrier in sales in 1997. The company began moving into the
European market in 1998. The company still was developing new drugs, with
258:. It was originally named Lim, Sung-ki Pharmaceutical Co., but it was quickly changed to Hanmi Pharmaceutical. The company originally started selling
1778:
364:
367:
drug candidates for diabetes; Sanofi paid $ 434 million upfront and up to $ 3.2 billion in milestones and royalties over 10%. The deal included
1625:
946:
1455:
1067:
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programs, including HM12525A; J&J paid $ 105 million upfront and the deal included $ 810M in milestones and royalties higher than 10%
2056:
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By around 2010, Hanmi's R&D had two areas of interest: developing longer-lasting peptide and protein therapeutics using its "
424:
On
September 28 Hanmi and Zentec Pharmaceuticals agreed that Zentec would market Hanmi's small molecule cancer drug candidate,
322:
for cancer and autoimmune diseases. Its strategy was to developmental incremental modifications of existing drugs, create new
615:
487:
On
September 30, 2016, Korean regulatory authorities issued a safety alert about olmutinib in which it described two cases of
181:
983:
1763:
1668:
352:; Lilly paid $ 50 million upfront and the deal included up to $ 640 million in milestones and royalties greater than 10%.
259:
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795:"RAPT THERAPEUTICS AND HANMI PHARMACEUTICAL ANNOUNCE COLLABORATION TO DEVELOP AND COMMERCIALIZE FLX475 IN ASIA"
458:
In August 2020, chairman and founder of Hanmi
Pharmaceutical Lim Sung-ki died of a chronic disease. He was 80.
417:
In May 2016 the Korean regulatory authority approved olmutinib as a second-line treatment for certain kinds of
1901:
1200:
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757:"UPDATED: After patient fatality, Hanmi loses Boehringer, gains Roche in $ 800M-plus cancer-partner shuffle"
379:
234:
64:
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928:"Following lethal tox report, Boehringer scraps plans for high-speed development, kills $ 730M Hanmi deal"
887:
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1986:
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738:"Deaths Lead Boehringer Ingelheim to Cancel 730 Million Cancer Deal With Hanmi Pharma Hanmi Stock Tanks"
462:
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On May 15, 2023, Athenex, which was Hanmi's U.S. partner for its anticancer product, Oraxol, filed for
299:
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638:"Hanmi Pharmaceutical to Step Up R&D Investment to Further Develop Core Technologies"
906:
869:"Smarting from failed Boehringer deal, Hanmi faces more pain from insider trading probe"
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274:. Hanmi started selling drugs in China in 1996. In 1994, the company began developing
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in 2004, and an anti-obesity drug using sibutramine mesilate in 2007. Hanmi and
275:
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656:"Research programme: long-acting conjugate therapeutics - Hanmi Pharmaceutical"
562:"Hanmi Pharmaceutical introduced first domestically developed lung cancer drug"
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701:"Janssen the latest Big Pharma to join Hanmi's South Korea deal machine"
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947:"Hanmi hit over failure to disclose olmutinib cancer trial side effect"
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signed an exclusive license outside of Asia for Hanmi's small molecule
186:
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776:"Hanmi Pharm downsizes license deal with Sanofi over diabetes drugs"
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An exclusive license in China with the
Chinese company ZAI Labs for
840:"Hanmi Pharm's US partner for anticancer drug files for bankruptcy"
719:"Sanofi, Hanmi Ink Up-to-$ 4.2B Long-Acting Diabetes Drug Alliance"
2005:
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907:"Prosecution charges 17 over Hanmi Pharmaceutical disclosure case"
238:
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679:"Lilly inks a $ 690M deal to get its hands on an autoimmune drug"
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An exclusive license outside of South Korea and China with the
1571:
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In August 2014 Hanmi exclusively licensed rights in China for
401:
In April 2016 Hanmi announced that it had acquired land near
439:
announced a deal for Hanmi's Phase I cancer drug candidate,
1643:
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An exclusive license outside of South Korea and China with
270:
antibiotics in 1987. By 1988 the company was listed in the
200:
616:"South Korea's Hanmi to spend $ 200M in China expansion"
984:"Hanmi calls time on troubled Tagrisso rival olmutinib"
2042:
Companies that filed for Chapter 11 bankruptcy in 2023
965:"Zai Lab returns China rights for olmutinib to Hanmi"
117:
888:"Hanmi Pharm employees charged over insider trading"
538:"Hanmi Pharmaceutical raided over alleged info leak"
254:
Hanmi was founded in 1973 by Lim Sung-ki, who was a
723:
GEN -- Genetic Engineering & Biotechnology News
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886:Mi-jung, Bae; Tae-yang, Yoo (December 2, 2012).
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355:In November 2015 Hanmi signed three agreements:
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8:
2037:Pharmaceutical companies established in 1973
318:" technology, and developing small molecule
290:tablets in 2001, 24-hour controlled-release
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19:
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813:"Hanmi Pharmaceutical chairman dies at 80"
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491:, one of which was fatal, and a case of
365:Glucagon-like peptide-1 receptor agonist
2032:Pharmaceutical companies of South Korea
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414:firm set up by Sung-ki and colleagues.
2052:Companies listed on the Korea Exchange
2027:Manufacturing companies based in Seoul
129:
7:
410:related fields, including through a
262:powder, and would expand to produce
905:Ji-young, Sohn (14 December 2016).
793:Bitting, Angela (3 December 2019).
755:Taylor, Phil (September 30, 2016).
266:antibiotics in 1985 and injectable
16:South Korean pharmaceutical company
892:Pulse by Maeil Business News Korea
774:Chan-ok, Shin (29 December 2016).
736:Terry, Mark (September 30, 2016).
536:Ji-young, Sohn (17 October 2016).
14:
1040:Business data for Hanmi Science:
926:Carroll, John (October 1, 2016).
614:Keenan, Joseph (April 14, 2016).
1099:
867:Taylor, Phil (October 7, 2016).
677:Garde, Damian (March 19, 2015).
509:List of pharmaceutical companies
474:Employee insider trading scandal
25:
1013:Business data for Hanmi Pharm:
982:Taylor, Phil (April 13, 2018).
560:Dong-chan, Jhoo (20 May 2016).
294:tablets and a new salt form of
1764:NH Investment & Securities
699:Lane, EJ (November 10, 2015).
326:, and to develop novel drugs.
229:
219:
161:
145:
1:
945:Adams, Ben (April 17, 2017).
260:Trimethoprim/sulfamethoxazole
514:Manufacturing in South Korea
431:On September 29, Hanmi and
201:
187:
76:; 51 years ago
2073:
2057:Companies in the KOSPI 200
1439:Hyosung Advanced Materials
636:Kim, Marie (4 July 2016).
489:toxic epidermal necrolysis
419:non-small cell lung cancer
348:inhibitor in the field of
320:tyrosine-kinase inhibitors
1856:Samsung Fire & Marine
1841:Samsung Electro-Mechanics
1466:Hyundai Marine & Fire
1116:
483:Olmutinib safety concerns
237:that is headquartered in
132:
40:
24:
1506:Industrial Bank of Korea
1446:Hyundai Department Store
493:Stevens–Johnson syndrome
346:Bruton's tyrosine kinase
340:In March 2015 Hanmi and
278:. The company broke the
1914:Shinsegae International
1201:Daewoong Pharmaceutical
845:Korea Biomedical Review
380:Janssen Pharmaceuticals
1741:Mirae Asset Securities
1715:Lotte Tour Development
1706:Lotte Energy Materials
235:pharmaceutical company
1796:PI Advanced Materials
1471:Hyundai Mipo Dockyard
1324:Hankook & Company
463:Chapter 11 bankruptcy
435:'s cancer subsidiary
304:strategic partnership
211:Hanmi Pharm Co., Ltd.
20:Hanmi Pharm Co., Ltd.
1402:HD Hyundai Infracore
1287:Green Cross Holdings
589:Hanmi Pharmaceutical
443:, which targets the
233:) is a South Korean
182:Revised Romanization
2047:South Korean brands
1851:Samsung Engineering
1846:Samsung Electronics
1815:POSCO International
1703:Lotte Fine Chemical
1631:Kumho Petrochemical
1602:Korea Petrochemical
1393:HD Hyundai Electric
1279:Grand Korea Leisure
725:. November 5, 2015.
350:autoimmune diseases
333:, a small molecule
21:
1881:Samsung Securities
1664:LG Energy Solution
1513:JB Financial Group
1125:Amorepacific Group
2014:
2013:
2002:Youngone Holdings
1991:Youlchon Chemical
1972:Ssangyong C&E
1902:Shinhan Financial
1826:Samsung Biologics
1577:Kiwoom Securities
1250:Doosan Enerbility
971:. April 11, 2018.
799:Rapt Therapeutics
388:metabolic disease
324:combination drugs
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196:McCune–Reischauer
128:
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1936:SK IE Technology
1736:Meritz Financial
1732:LX International
1599:Korea Investment
1451:Hyundai Elevator
1397:HD Hyundai Heavy
1379:Hanwha Solutions
1364:Hanwha Aerospace
1311:Hanall Biopharma
1260:Ecopro Materials
1254:Doosan Fuel Cell
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1831:Samsung C&T
1819:S-1 Corporation
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1349:Hansol Chemical
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268:Ceftriaxone
227::
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520:References
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316:Lapscovery
296:Amlodipine
292:Nifedipine
284:Paclitaxel
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220:한미약품 주식회사
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