490:
were raided by Korean regulatory authorities in mid-October based on evidence that insider knowledge of the
Boehringer termination was passed to third parties, who shorted the stock prior to the announcement on the 30th. In December three Hanmi employees were among 17 people indicted for insider trading; 25 people were fined, and 45 people were found to have made illegal trades that took around 3.3 billion won ($ 2.83 million) in profits based on the information.
1112:
38:
489:
On the evening of
September 29, 2016, Hanmi announced the Roche deal, causing its stock to rise; Hanmi was notified by Boehringer that evening that Boehringer was terminating their deal, and the company announced the termination on the morning of the 30th, causing its stock to crash. Hanmi's offices
420:
province of China, where it would build a manufacturing plant and R&D facility; at that time it already had a facility in
Beijing. In July Hanmi said it intended to invest more heavily in developing candidate substances of promising new drugs at an early stage in new pharmaceutical and biotech
509:
In April 2018 Hanmi was found to have violated two laws in Korea by not disclosing adverse effects of olmutinib sooner. In that month Zai said it was dropping olmutinib and a few days later Hanmi said it was terminating development of the drug.
461:
In
December 2016 the Sanofi deal was reduced in scope, with Hanmi receiving back rights to the once-weekly insulin and the combination GLP1-RA/insulin product, and agreeing to repay Sanofi $ 250 million of the $ 434 million upfront payment.
465:
On
December 3, 2019, Rapt Therapeutics and Hanami Pharmaceutical announced collaboration to develop and commercialize FLX475 in Asia. FLX475 is an oral, small molecule CCR4 antagonist in development for the treatment of multiple cancers.
506:; Boeheringer announced the termination its deal with Hanmi the same day, citing that the decision came after a review of "all available clinical data" on the drug, and also referring to competing drugs.
2052:
2047:
648:
2042:
805:
382:, a long-acting glucagon-like peptide-1 receptor agonist; an insulin intended to be delivered once per week, and a fixed-dosed weekly GLP1-RA/insulin drug combination.
2062:
2037:
879:
938:
348:, to the Chinese company Luye Pharma; in February 2015 Hanmi licensed rights in the rest of the world outside of South Korea to Spectrum Pharmaceuticals.
729:
293:
100,000,000,000 barrier in sales in 1997. The company began moving into the
European market in 1998. The company still was developing new drugs, with
269:. It was originally named Lim, Sung-ki Pharmaceutical Co., but it was quickly changed to Hanmi Pharmaceutical. The company originally started selling
1789:
375:
378:
drug candidates for diabetes; Sanofi paid $ 434 million upfront and up to $ 3.2 billion in milestones and royalties over 10%. The deal included
1636:
957:
1466:
1078:
1567:
401:
programs, including HM12525A; J&J paid $ 105 million upfront and the deal included $ 810M in milestones and royalties higher than 10%
2067:
1100:
767:
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By around 2010, Hanmi's R&D had two areas of interest: developing longer-lasting peptide and protein therapeutics using its "
435:
On
September 28 Hanmi and Zentec Pharmaceuticals agreed that Zentec would market Hanmi's small molecule cancer drug candidate,
333:
for cancer and autoimmune diseases. Its strategy was to developmental incremental modifications of existing drugs, create new
626:
498:
On
September 30, 2016, Korean regulatory authorities issued a safety alert about olmutinib in which it described two cases of
192:
994:
1774:
1679:
363:; Lilly paid $ 50 million upfront and the deal included up to $ 640 million in milestones and royalties greater than 10%.
270:
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975:
806:"RAPT THERAPEUTICS AND HANMI PHARMACEUTICAL ANNOUNCE COLLABORATION TO DEVELOP AND COMMERCIALIZE FLX475 IN ASIA"
469:
In August 2020, chairman and founder of Hanmi
Pharmaceutical Lim Sung-ki died of a chronic disease. He was 80.
428:
In May 2016 the Korean regulatory authority approved olmutinib as a second-line treatment for certain kinds of
1912:
1211:
1093:
855:
768:"UPDATED: After patient fatality, Hanmi loses Boehringer, gains Roche in $ 800M-plus cancer-partner shuffle"
390:
245:
75:
1876:
1751:
1746:
1725:
939:"Following lethal tox report, Boehringer scraps plans for high-speed development, kills $ 730M Hanmi deal"
898:
206:
1997:
1605:
1491:
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1379:
749:"Deaths Lead Boehringer Ingelheim to Cancel 730 Million Cancer Deal With Hanmi Pharma Hanmi Stock Tanks"
473:
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On May 15, 2023, Athenex, which was Hanmi's U.S. partner for its anticancer product, Oraxol, filed for
310:
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458:; Roche agreed to pay $ 80 million upfront, and the deal included $ 830 million in milestones.
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649:"Hanmi Pharmaceutical to Step Up R&D Investment to Further Develop Core Technologies"
917:
880:"Smarting from failed Boehringer deal, Hanmi faces more pain from insider trading probe"
548:
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285:. Hanmi started selling drugs in China in 1996. In 1994, the company began developing
2031:
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439:; Zentec paid $ 80 million upfront, with $ 830 million in milestones, and royalties.
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in 2004, and an anti-obesity drug using sibutramine mesilate in 2007. Hanmi and
286:
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667:"Research programme: long-acting conjugate therapeutics - Hanmi Pharmaceutical"
573:"Hanmi Pharmaceutical introduced first domestically developed lung cancer drug"
37:
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712:"Janssen the latest Big Pharma to join Hanmi's South Korea deal machine"
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958:"Hanmi hit over failure to disclose olmutinib cancer trial side effect"
355:
signed an exclusive license outside of Asia for Hanmi's small molecule
197:
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787:"Hanmi Pharm downsizes license deal with Sanofi over diabetes drugs"
404:
An exclusive license in China with the
Chinese company ZAI Labs for
851:"Hanmi Pharm's US partner for anticancer drug files for bankruptcy"
730:"Sanofi, Hanmi Ink Up-to-$ 4.2B Long-Acting Diabetes Drug Alliance"
2016:
1978:
1815:
1527:
1274:
918:"Prosecution charges 17 over Hanmi Pharmaceutical disclosure case"
249:
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690:"Lilly inks a $ 690M deal to get its hands on an autoimmune drug"
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An exclusive license outside of South Korea and China with the
1582:
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In August 2014 Hanmi exclusively licensed rights in China for
412:
In April 2016 Hanmi announced that it had acquired land near
450:
announced a deal for Hanmi's Phase I cancer drug candidate,
1654:
370:
An exclusive license outside of South Korea and China with
281:
antibiotics in 1987. By 1988 the company was listed in the
211:
627:"South Korea's Hanmi to spend $ 200M in China expansion"
995:"Hanmi calls time on troubled Tagrisso rival olmutinib"
2053:
Companies that filed for Chapter 11 bankruptcy in 2023
976:"Zai Lab returns China rights for olmutinib to Hanmi"
128:
899:"Hanmi Pharm employees charged over insider trading"
549:"Hanmi Pharmaceutical raided over alleged info leak"
265:
Hanmi was founded in 1973 by Lim Sung-ki, who was a
734:
GEN -- Genetic Engineering & Biotechnology News
205:
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99:
81:
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897:Mi-jung, Bae; Tae-yang, Yoo (December 2, 2012).
705:
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366:In November 2015 Hanmi signed three agreements:
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8:
2048:Pharmaceutical companies established in 1973
329:" technology, and developing small molecule
301:tablets in 2001, 24-hour controlled-release
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30:
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824:"Hanmi Pharmaceutical chairman dies at 80"
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502:, one of which was fatal, and a case of
376:Glucagon-like peptide-1 receptor agonist
2043:Pharmaceutical companies of South Korea
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425:firm set up by Sung-ki and colleagues.
2063:Companies listed on the Korea Exchange
2038:Manufacturing companies based in Seoul
140:
7:
421:related fields, including through a
273:powder, and would expand to produce
916:Ji-young, Sohn (14 December 2016).
804:Bitting, Angela (3 December 2019).
766:Taylor, Phil (September 30, 2016).
277:antibiotics in 1985 and injectable
27:South Korean pharmaceutical company
903:Pulse by Maeil Business News Korea
785:Chan-ok, Shin (29 December 2016).
747:Terry, Mark (September 30, 2016).
547:Ji-young, Sohn (17 October 2016).
25:
1051:Business data for Hanmi Science:
937:Carroll, John (October 1, 2016).
625:Keenan, Joseph (April 14, 2016).
1110:
878:Taylor, Phil (October 7, 2016).
688:Garde, Damian (March 19, 2015).
520:List of pharmaceutical companies
485:Employee insider trading scandal
36:
1024:Business data for Hanmi Pharm:
993:Taylor, Phil (April 13, 2018).
571:Dong-chan, Jhoo (20 May 2016).
305:tablets and a new salt form of
1775:NH Investment & Securities
710:Lane, EJ (November 10, 2015).
337:, and to develop novel drugs.
240:
230:
172:
156:
1:
956:Adams, Ben (April 17, 2017).
271:Trimethoprim/sulfamethoxazole
525:Manufacturing in South Korea
442:On September 29, Hanmi and
212:
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87:; 51 years ago
2084:
2068:Companies in the KOSPI 200
1450:Hyosung Advanced Materials
647:Kim, Marie (4 July 2016).
500:toxic epidermal necrolysis
430:non-small cell lung cancer
359:inhibitor in the field of
331:tyrosine-kinase inhibitors
1867:Samsung Fire & Marine
1852:Samsung Electro-Mechanics
1477:Hyundai Marine & Fire
1127:
494:Olmutinib safety concerns
248:that is headquartered in
143:
51:
35:
1517:Industrial Bank of Korea
1457:Hyundai Department Store
504:Stevens–Johnson syndrome
357:Bruton's tyrosine kinase
351:In March 2015 Hanmi and
289:. The company broke the
1925:Shinsegae International
1212:Daewoong Pharmaceutical
856:Korea Biomedical Review
391:Janssen Pharmaceuticals
1752:Mirae Asset Securities
1726:Lotte Tour Development
1717:Lotte Energy Materials
246:pharmaceutical company
1807:PI Advanced Materials
1482:Hyundai Mipo Dockyard
1335:Hankook & Company
474:Chapter 11 bankruptcy
446:'s cancer subsidiary
315:strategic partnership
222:Hanmi Pharm Co., Ltd.
31:Hanmi Pharm Co., Ltd.
1413:HD Hyundai Infracore
1298:Green Cross Holdings
600:Hanmi Pharmaceutical
454:, which targets the
244:) is a South Korean
193:Revised Romanization
18:Hanmi Pharmaceutical
2058:South Korean brands
1862:Samsung Engineering
1857:Samsung Electronics
1826:POSCO International
1714:Lotte Fine Chemical
1642:Kumho Petrochemical
1613:Korea Petrochemical
1404:HD Hyundai Electric
1290:Grand Korea Leisure
736:. November 5, 2015.
361:autoimmune diseases
344:, a small molecule
32:
1892:Samsung Securities
1675:LG Energy Solution
1524:JB Financial Group
1136:Amorepacific Group
2025:
2024:
2013:Youngone Holdings
2002:Youlchon Chemical
1983:Ssangyong C&E
1913:Shinhan Financial
1837:Samsung Biologics
1588:Kiwoom Securities
1261:Doosan Enerbility
982:. April 11, 2018.
810:Rapt Therapeutics
399:metabolic disease
335:combination drugs
219:
218:
207:McCune–Reischauer
139:
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16:(Redirected from
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1947:SK IE Technology
1747:Meritz Financial
1743:LX International
1610:Korea Investment
1462:Hyundai Elevator
1408:HD Hyundai Heavy
1390:Hanwha Solutions
1375:Hanwha Aerospace
1322:Hanall Biopharma
1271:Ecopro Materials
1265:Doosan Fuel Cell
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1247:Dongwon Systems
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