Knowledge (XXG)

Hedamycin

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InChI=1S/C41H50N2O11/c1-16-11-22-30(37-28(16)24(44)14-27(53-37)41(6)39(54-41)36-18(3)52-36)35(48)31-29(34(22)47)20(25-13-23(42(7)8)32(45)17(2)50-25)12-21(33(31)46)26-15-40(5,43(9)10)38(49)19(4)51-26/h11-12,14,17-19,23,25-26,32,36,38-39,45-46,49H,13,15H2,1-10H3
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Tu, L. C.; Melendy, T.; Beerman, T. A. (2004). "DNA damage responses triggered by a highly cytotoxic monofunctional DNA alkylator, hedamycin, a pluramycin antitumor antibiotic".
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CC1C(C(CC(O1)C2=CC(=C(C3=C2C(=O)C4=C(C3=O)C5=C(C(=C4)C)C(=O)C=C(O5)C6(C(O6)C7C(O7)C)C)O)C8CC(C(C(O8)C)O)(C)N(C)C)N(C)C)O
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Except where otherwise noted, data are given for materials in their
70: 60: 153: 387: 135: 46: 407: 8: 414: 400: 168: 110: 15: 315: 214: 189: 164: 302:is a chemical compound with potential 196:Key: RZOFHOWMWMTHDX-UHFFFAOYSA-N 90: 7: 368: 366: 126: 386:. You can help Knowledge (XXG) by 14: 370: 250: 244: 22: 284:(at 25 °C , 100 kPa). 256: 238: 1: 325:Molecular Cancer Therapeutics 454: 365: 337:10.1158/1535-7163.577.3.5 306:and anticancer activity. 278: 225: 205: 180: 30: 21: 438:Aromatic compound stubs 378:This article about an 274: g·mol 18: 288:Infobox references 16: 395: 394: 296:Chemical compound 294: 293: 149:CompTox Dashboard 72:Interactive image 445: 416: 409: 402: 374: 367: 357: 356: 320: 273: 258: 252: 246: 240: 233:Chemical formula 173: 172: 157: 155: 139: 128: 114: 94: 74: 50: 26: 19: 453: 452: 448: 447: 446: 444: 443: 442: 423: 422: 421: 420: 363: 361: 360: 322: 321: 317: 312: 297: 290: 285: 271: 261: 255: 249: 243: 235: 221: 218: 213: 212: 201: 198: 197: 194: 188: 187: 176: 166:DTXSID301028214 158: 151: 142: 129: 117: 97: 77: 64: 53: 40: 12: 11: 5: 451: 449: 441: 440: 435: 425: 424: 419: 418: 411: 404: 396: 393: 392: 382:compound is a 375: 359: 358: 331:(5): 577–585. 314: 313: 311: 308: 295: 292: 291: 286: 282:standard state 279: 276: 275: 269: 263: 262: 259: 253: 247: 241: 236: 231: 228: 227: 223: 222: 220: 219: 216: 208: 207: 206: 203: 202: 200: 199: 195: 192: 191: 183: 182: 181: 178: 177: 175: 174: 161: 159: 147: 144: 143: 141: 140: 132: 130: 122: 119: 118: 116: 115: 107: 105: 99: 98: 96: 95: 87: 85: 79: 78: 76: 75: 67: 65: 58: 55: 54: 52: 51: 43: 41: 36: 33: 32: 28: 27: 13: 10: 9: 6: 4: 3: 2: 450: 439: 436: 434: 431: 430: 428: 417: 412: 410: 405: 403: 398: 397: 391: 389: 385: 381: 376: 373: 369: 364: 354: 350: 346: 342: 338: 334: 330: 326: 319: 316: 309: 307: 305: 301: 289: 283: 277: 270: 268: 265: 264: 237: 234: 230: 229: 224: 215: 211: 204: 190: 186: 179: 171: 167: 163: 162: 160: 150: 146: 145: 138: 134: 133: 131: 125: 121: 120: 113: 109: 108: 106: 104: 101: 100: 93: 92:ChEMBL1979887 89: 88: 86: 84: 81: 80: 73: 69: 68: 66: 62: 57: 56: 49: 45: 44: 42: 39: 35: 34: 29: 25: 20: 388:expanding it 377: 362: 328: 324: 318: 299: 298: 31:Identifiers 433:Antibiotics 226:Properties 427:Categories 310:References 304:antibiotic 267:Molar mass 103:ChemSpider 59:3D model ( 48:11048-97-8 38:CAS Number 17:Hedamycin 300:Hedamycin 380:aromatic 345:15141015 353:1323976 272:746.854 124:PubChem 112:5034760 351:  343:  210:SMILES 83:ChEMBL 349:S2CID 185:InChI 137:98033 61:JSmol 384:stub 341:PMID 333:doi 154:EPA 127:CID 429:: 347:. 339:. 327:. 260:11 248:50 242:41 415:e 408:t 401:v 390:. 355:. 335:: 329:3 257:O 254:2 251:N 245:H 239:C 156:) 152:( 63:)

Index


CAS Number
11048-97-8
JSmol
Interactive image
ChEMBL
ChEMBL1979887
ChemSpider
5034760
PubChem
98033
CompTox Dashboard
DTXSID301028214
Edit this at Wikidata
InChI
SMILES
Chemical formula
Molar mass
standard state
Infobox references
antibiotic
doi
10.1158/1535-7163.577.3.5
PMID
15141015
S2CID
1323976
Stub icon
aromatic
stub

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