912:
860:
848:
836:
824:
1392:
1558:
670:
901:
1512:
rates were higher in developed regions, with the greatest rates in the
Americas (1.5 per 100,000), East Mediterranean Region (1.5 per 100,000), and Europe (2.0 per 100,000). The East Mediterranean Region also has the highest age-standardized mortality rate of 1.0 per 100,000, which is mainly attributed to lifestyle and environmental risk factors associated with transitional economies such as smoking, obesity, physical inactivity, and reproductive behaviors, as well as availability of diagnostic practices and awareness of the disease.
53:
1379:
study, after two cycles of ABVD chemotherapy, 83% of people were free of disease at 3 years if they had a negative PET versus only 28% in those with positive PET scans. This prognostic method improves on FFP estimates based on the seven conventional factors. Several trials are underway to see if PET-based risk adapted response can be used to improve a person's outcomes by changing chemotherapy early in people who are not responding.
682:
1054:(also known as Matulane). The treatment is usually administered in four week cycles, often for six cycles. MSD and VCR are administered intravenously, while procarbazine and prednisone are pills taken orally. MOPP was the first combination chemotherapy brought in that achieved a high success rate. It was developed at the National Cancer Institute in the 1960s by a team that included Vincent DeVita Jr.
1242:(which is a monoclonal antibody against CD20) is not routinely used to treat Hodgkin lymphoma due to the lack of CD20 surface antigens in most cases. The use of rituximab in Hodgkin lymphoma, including the lymphocyte predominant subtype has been recently reviewed. The evidence is very uncertain about the effect of Nivolumab for patients with a Hodgkin's lymphoma e.g. on the overall survival.
1257:(sometimes shortened to EBRT or XRT). Radiation oncologists deliver external beam radiation therapy to the lymphoma from a machine called a linear accelerator which produces high energy X-rays and electrons. People usually describe treatments as painless and similar to getting an X-ray. Treatments last less than 30 minutes each.
1607:
independently reported on a series of patients with the same disease that
Hodgkin had previously described. Wilks, a successor to Hodgkin at Guy's Hospital, was unaware of Hodgkin's prior work on the subject. Bright informed Wilks of Hodgkin's contribution and in 1865, Wilks published a second paper,
1282:
within the radiation therapy field. Most people with early-stage disease are now treated with abbreviated chemotherapy and involved site radiation therapy rather than with radiation therapy alone. Clinical research strategies are exploring reduction of the duration of chemotherapy and dose and volume
1245:
Increased age is an adverse risk factor for
Hodgkin lymphoma, but in general elderly people (≥ 60 years of age) without major comorbidities are sufficiently fit to tolerate therapy with curative intent. Despite this, treatment outcome in the elderly patient is not comparable to that of younger people
1092:
regimen is typically only half as long as the ABVD but involves a more intensive chemotherapy schedule and incorporates radiation therapy. In a randomised controlled study in Italy, Stanford V was inferior to ABVD; however, this study has been heavily criticized due to its incorrect administration of
4692:
Fermé C, Eghbali H, Meerwaldt JH, Rieux C, Bosq J, Berger F, Girinsky T, Brice P, van't Veer MB, Walewski JA, Lederlin P, Tirelli U, Carde P, Van den Neste E, Gyan E, Monconduit M, Diviné M, Raemaekers JM, Salles G, Noordijk EM, Creemers GJ, Gabarre J, Hagenbeek A, Reman O, Blanc M, Thomas J, Vié B,
1548:
In 2016, there were 8,389 new cases and 1,000 mortalities attributed to
Hodgkin lymphoma, a decrease from the 8,625 new cases and 1,120 mortalities in 2015. As of January 1, 2016, the 5-year limited duration prevalence of Hodgkin lymphoma was 37,513 representing 0.71% of all diagnosed cancers in the
1249:
Recently, two novel targeted drugs have been developed for relapsing and refractory HL patients; Brentuximab vedotin, a CD30 antibody conjugated with a cytotoxic component MMAE, and the checkpoint inhibitors, Nivolumab and
Pembrolizumab. This has been an important step in the treatment for the few,
1099:
is a form of treatment for stages > II mainly used in Europe. The cure rate with the BEACOPP esc. regimen is approximately 10–15% higher than with standard ABVD in advanced stages. This was shown in a paper in The New
England Journal of Medicine (Diehl et al.), but US physicians still favor ABVD,
2259:
Vos T, Allen C, Arora M, Barber RM, Bhutta ZA, Brown A, Carter A, Casey DC, Charlson FJ, Chen AZ, Coggeshall M, Cornaby L, Dandona L, Dicker DJ, Dilegge T, Erskine HE, Ferrari AJ, Fitzmaurice C, Fleming T, Forouzanfar MH, Fullman N, Gething PW, Goldberg EM, Graetz N, Haagsma JA, Hay SI, Johnson CO,
2312:
Wang H, Naghavi M, Allen C, Barber RM, Bhutta ZA, Carter A, Casey DC, Charlson FJ, Chen AZ, Coates MM, Coggeshall M, Dandona L, Dicker DJ, Erskine HE, Ferrari AJ, Fitzmaurice C, Foreman K, Forouzanfar MH, Fraser MS, Fullman N, Gething PW, Goldberg EM, Graetz N, Haagsma JA, Hay SI, Huynh C, Johnson
1260:
For lymphomas, there are a few different ways radiation oncologists target the cancer cells. Involved site radiation is when the radiation oncologists give radiation only to those parts of the person's body known to have the cancer. Very often, this is combined with chemotherapy. Radiation therapy
1511:
In 2010, globally it resulted in about 18,000 deaths down from 19,000 in 1990. In 2012, there were an estimated 65,950 cases and 25,469 deaths from
Hodgkin lymphoma worldwide, with 28,852 and 37,098 cases occurring in developed and developing countries, respectively. However, the age-standardized
1378:
More recently, the use of positron emission tomography (PET) early after commencing chemotherapy has demonstrated to have powerful prognostic ability. This enables assessment of an individual's response to chemotherapy as the PET activity switches off rapidly in people who are responding. In this
1382:
The evidence is very uncertain about the effect of negative (= good prognosis) or positive (= bad prognosis) interim PET scan results for patients with a
Hodgkin's lymphoma on the progression-free survival. Negative interim PET scan results may result in an increase in progression-free survival
1322:
In 1998, an international effort identified seven prognostic factors that accurately predict the success rate of conventional treatment in people with locally extensive or advanced-stage
Hodgkin lymphoma. Freedom from progression (FFP) at five years was directly related to the number of factors
1305:
Adding physical exercises to the standard treatment for adult patients with haematological malignancies like
Hodgkin lymphoma may result in little to no difference in the mortality, the quality of life and the physical functioning. These exercises may result in a slight reduction in depression.
816:
The absence of systemic symptoms is signified by adding "A" to the stage; the presence of systemic symptoms is signified by adding "B" to the stage. For localised extranodal extension from mass of nodes that does not advance the stage, subscript "E" is added. Splenic involvement is signified by
1502:
curve for the number of cases; that is, it occurs most frequently in two separate age groups, the first being young adulthood (age 15–35) and the second being in those over 55 years old although these peaks may vary slightly with nationality. Overall, it is more common in males, except for the
508:
specimen (the cell composition around the Reed–Sternberg cell(s)). Presence of EBV in Reed-Sternberg cells is most commonly found in the subtypes lymphocyte depleted HL (>70%) and mixed cellularity HL (70%), whilst being less prevalent in lymphocyte-rich HL (40%) and relatively uncommon by
476:
The two main types of Hodgkin lymphoma are classic Hodgkin lymphoma and nodular lymphocyte-predominant Hodgkin lymphoma. The prevalence of classic Hodgkin lymphoma and nodular-lymphocyte Hodgkin lymphoma are about 90 and 10%, respectively. The morphology, phenotype, molecular features, and,
4513:
Estcourt L, Stanworth S, Doree C, Hopewell S, Murphy MF, Tinmouth A, Heddle N, et al. (Cochrane Haematological Malignancies Group) (May 2012). "Prophylactic platelet transfusion for prevention of bleeding in patients with haematological disorders after chemotherapy and stem cell
933:(RSC) (typical and variants) admixed within a reactive cell infiltrate composed of variable proportions of lymphocytes, histiocytes, eosinophils, and plasma cells. The Reed–Sternberg cells are identified as large often bi-nucleated cells with prominent nucleoli and an unusual
4362:
Specht L, Yahalom J, Illidge T, Berthelsen AK, Constine LS, Eich HT, Girinsky T, Hoppe RT, Mauch P, Mikhaeel NG, Ng A (July 2014). "Modern radiation therapy for Hodgkin lymphoma: field and dose guidelines from the international lymphoma radiation oncology group (ILROG)".
1366:
Other studies have reported the following to be the most important adverse prognostic factors: mixed-cellularity or lymphocyte-depleted histologies, male sex, large number of involved nodal sites, advanced stage, age of 40 years or more, the presence of B symptoms, high
1742:, Canadian child actor, was diagnosed in 1994 at age 9. Treatments that rendered him cancer-free, including chemotherapy, a bone marrow transplant, and radiation, left him with permanent lung and respiratory problems and he died in 2001 just after turning 16.
416:
sign of Hodgkin lymphoma. The pain typically has an onset within minutes after ingesting alcohol, and is usually felt as coming from the vicinity where there is an involved lymph node. The pain has been described as either sharp and stabbing or dull and
289:. The choice of treatment often depends on how advanced the cancer has become and whether or not it has favorable features. If the disease is detected early, a cure is often possible. In the United States, 88% of people diagnosed with Hodgkin lymphoma
948:
Characteristics of classic Reed–Sternberg cells include large size (20–50 micrometres), abundant, amphophilic, finely granular/homogeneous cytoplasm; two mirror-image nuclei (owl eyes) each with an eosinophilic nucleolus and a thick nuclear membrane
6038:
1265:. Radiation to below the diaphragm to the abdomen, spleen or pelvis is called inverted-Y field radiation. Total nodal irradiation is when the therapist gives radiation to all the lymph nodes in the body to destroy cells that may have spread.
6503:
6488:
6473:
4547:"Comparison of different platelet count thresholds to guide administration of prophylactic platelet transfusion for preventing bleeding in people with haematological disorders after myelosuppressive chemotherapy or stem cell transplantation"
3594:
Wienand K, Chapuy B, Stewart C, Dunford AJ, Wu D, Kim J, Kamburov A, Wood TR, Cader FZ, Ducar MD, Thorner AR, Nag A, Heubeck AT, Buonopane MJ, Redd RA, Bojarczuk K, Lawton LN, Armand P, Rodig SJ, Fromm JR, Getz G, Shipp MA (December 2019).
1314:
Treatment of Hodgkin's disease has been improving over the past few decades. Recent trials that have made use of new types of chemotherapy have indicated higher survival rates than have previously been seen. In a 2007 European trial, the
300:
In 2015, about 574,000 people globally had Hodgkin lymphoma, and 23,900 (4.2%) died. In the United States, 0.2% of people are affected at some point in their life. Most people are diagnosed with the disease between the ages of 20 and 40.
784:(which involves opening the abdominal cavity and visually inspecting for tumors) were performed. Lymphangiograms or laparotomies are very rarely performed, having been supplanted by improvements in imaging with the CT scan and PET scan.
6306:
403:
Pain following alcohol consumption: Classically, involved nodes are painful after alcohol consumption, though this phenomenon is very uncommon, occurring in only two to three percent of people with Hodgkin lymphoma, thus having a low
1100:
maybe because some physicians think that BEACOPP induces more secondary leukemia. However, this seems negligible compared to the higher cure rates. BEACOPP is more expensive because of the requirement for concurrent treatment with
579:
Is a common subtype and is composed of numerous classic RS cells admixed with numerous inflammatory cells including lymphocytes, histiocytes, eosinophils, and plasma cells without sclerosis. This type is most often associated with
3860:"ABVD versus modified stanford V versus MOPPEBVCAD with optional and limited radiotherapy in intermediate- and advanced-stage Hodgkin's lymphoma: final results of a multicenter randomized trial by the Intergruppo Italiano Linfomi"
880:
Affected lymph nodes (most often, laterocervical lymph nodes) are enlarged, but their shape is preserved because the capsule is not invaded. Usually, the cut surface is white-grey and uniform; in some histological subtypes (e.g.
1985:, Portuguese professional footballer, diagnosed in 2017 Tengarrinha died on October 30, 2021, at the age of 32. Hours later, his former teams FC Porto and Boavista FC paid tribute to him before the local derby. playing for
1531:
Hodgkin lymphoma accounts for 0.6% of all male cancer cases, and 0.4% of all female cancer cases in Canada. In 2017, approximately 990 Canadians will be diagnosed with Hodgkin lymphoma, and 140 will die of the disease.
716:(IL-21), which was once thought to be exclusive to T-cells. This feature may explain the behavior of classic Hodgkin lymphoma, including clusters of other immune cells gathered around HL cells (infiltrate) in cultures.
7524:
1507:
variant, which is slightly more common in females. The annual number of cases of Hodgkin lymphoma is 2.7 per 100,000 per persons per year, and the disease accounts for slightly less than 1% of all cancers worldwide.
1273:
The high cure rates and long survival of many people with Hodgkin lymphoma has led to a high concern with late adverse effects of treatment, including cardiovascular disease and second malignancies such as acute
1323:
present in a person. The five-year FFP for people with zero factors is 84%. Each additional factor lowers the five-year FFP rate by 7%, such that the five-year FFP for a person with five or more factors is 42%.
1283:
of radiation therapy in an attempt to reduce late morbidity and mortality of treatment while maintaining high cure rates. Hospitals are also treating those who respond quickly to chemotherapy with no radiation.
423:: Nonspecific back pain (pain that cannot be localised or its cause determined by examination or scanning techniques) has been reported in some cases of Hodgkin lymphoma. The lower back is most often affected.
464:(PET) is used to detect small deposits that do not show on CT scanning. PET scans are also useful in functional imaging (by using a radiolabeled glucose to image tissues of high metabolism). In some cases, a
7268:
3708:
Aldin A, Umlauff L, Estcourt LJ, Collins G, Moons KG, Engert A, Kobe C, von Tresckow B, Haque M, Foroutan F, Kreuzberger N, Trivella M, Skoetz N, et al. (Cochrane Haematology Group) (January 2020).
995:
or chemotherapy. The choice of treatment depends on the age, sex, bulk and the histological subtype of the disease. Adding localised radiation therapy after the chemotherapy regimen may provide a longer
6046:
2315:"Global, regional, and national life expectancy, all-cause mortality, and cause-specific mortality for 249 causes of death, 1980–2015: a systematic analysis for the Global Burden of Disease Study 2015"
581:
271:
1297:
It is possible that patients undergoing a chemotherapy need a platelet transfusion. If a stem cell transplantation is necessary for the treatment of a relapse, graft-versus-host diseases might occur.
1383:
compared if the adjusted result was measured. Negative interim PET scan results probably result in a large increase in the overall survival compared to those with a positive interim PET scan result,
3858:
Gobbi PG, Levis A, Chisesi T, Broglia C, Vitolo U, Stelitano C, Pavone V, Cavanna L, Santini G, Merli F, Liberati M, Baldini L, Deliliers GL, Angelucci E, Bordonaro R, Federico M (December 2005).
2262:"Global, regional, and national incidence, prevalence, and years lived with disability for 310 diseases and injuries, 1990–2015: a systematic analysis for the Global Burden of Disease Study 2015"
1056:
Although no longer the most effective combination, MOPP is still used after relapse or where the person has certain allergies or lung or heart problems which prevents the use of another regimen.
988:
The current approach for treatment aims to reduce the acute and long-term toxicities associated with Hodgkin lymphoma (e.g. cardiac damage and secondary cancers) and increase overall survival.
1600:. Hodgkin's paper went largely unnoticed, however, even though Bright highlighted it in an 1838 publication. Indeed, Hodgkin himself did not view his contribution as particularly significant.
6314:
4596:"Mesenchymal stromal cells as treatment or prophylaxis for acute or chronic graft-versus-host disease in haematopoietic stem cell transplant (HSCT) recipients with a haematological condition"
6822:
2921:
Lennon AM, Buchanan AH, Kinde I, Warren A, Honushefsky A, Cohain AT, Ledbetter DH, Sanfilippo F, Sheridan K, Rosica D, Adonizio CS, Hwang HJ, Lahouel K, Cohen JD, Douville C (2020-07-03).
963:
Lacunar RSC is large, with a single hyperlobulated nucleus, multiple, small nucleoli and eosinophilic cytoplasm which is retracted around the nucleus, creating an empty space ("lacunae").
452:
Hodgkin lymphoma must be distinguished from noncancerous causes of lymph node swelling (such as various infections) and from other types of cancer. Definitive diagnosis is by lymph node
1540:
Hodgkin lymphoma accounts for less than 1% of all cancer cases and deaths in the UK. Around 1,800 people were diagnosed with the disease in 2011, and around 330 people died in 2012.
5127:
6218:
1104:
to increase production of white blood cells. Currently, the German Hodgkin Study Group tests 8 cycles (8x) BEACOPP esc vs. 6x BEACOPP esc vs. 8x BEACOPP-14 baseline (HD15-trial).
6939:
6518:
584:
and may be confused with the early, so-called 'cellular' phase of the nodular sclerosing subtype. This type of Hodgkin lymphoma is most commonly seen in immunocompromised people.
5906:
5360:
7529:
911:
7338:
2455:
Grewal R, Irimie A, Naidoo N, Mohamed N, Petrushev B, Chetty M, Tomuleasa C, Abayomi EA (March 2018). "Hodgkin's lymphoma and its association with EBV and HIV infection".
752:: that is, they will undergo a series of tests and procedures that will determine what areas of the body are affected. These procedures may include documentation of their
3973:
Saini KS, Azim HA, Cocorocchio E, Vanazzi A, Saini ML, Raviele PR, Pruneri G, Peccatori FA (August 2011). "Rituximab in Hodgkin lymphoma: is the target always a hit?".
2850:"Occurrence of minimal change nephrotic syndrome in classic Hodgkin lymphoma is closely related to the induction of c-mip in Hodgkin-Reed Sternberg cells and podocytes"
270:. Diagnosis is conducted by confirming the presence of cancer and identifying RS cells in lymph node biopsies. The virus-positive cases are classified as a form of the
7552:
697:) are not expressed on all cells, Reed–Sternberg cells are usually of B cell origin. Although Hodgkin's is now frequently grouped with other B-cell malignancies, some
5633:
685:
CT image of a 46-year-old person with Hodgkin lymphoma, image at neck height. On the left side of the person's neck enlarged lymph nodes are visible (marked in red).
6904:
919:
724:
486:
259:
929:
Microscopic examination of the lymph node biopsy reveals complete or partial effacement of the lymph node architecture by scattered large malignant cells known as
7294:
2195:
4943:
859:
847:
835:
6633:
6262:
823:
4888:"International validation study for interim PET in ABVD-treated, advanced-stage hodgkin lymphoma: interpretation criteria and concordance rate among reviewers"
4594:
Fisher SA, Cutler A, Doree C, Brunskill SJ, Stanworth SJ, Navarrete C, Girdlestone J, et al. (Cochrane Haematological Malignancies Group) (January 2019).
2033:"Global and regional mortality from 235 causes of death for 20 age groups in 1990 and 2010: a systematic analysis for the Global Burden of Disease Study 2010"
1306:
Furthermore, aerobic physical exercises probably reduce fatigue. The evidence is very uncertain about the effect on anxiety and serious adverse events.
6984:
5164:
4398:
384:
is often present in people with Hodgkin lymphoma. The enlargement is seldom massive, and the size of the spleen may fluctuate during the course of treatment.
4836:"Chemotherapy alone or combined chemotherapy and involved field radiotherapy in favorable risk early-stage classical Hodgkin lymphoma-a 10 years experience"
1718:, a teenager whose refusal to undergo further conventional treatment after relapsing in 2006 resulted in a court battle and a change to Virginia laws about
7497:
6139:
727:(NLPHL) is another subtype of Hodgkin lymphoma distinct from classic Hodgkin lymphoma and is characterized by the presence of popcorn cells which express
7536:
7082:
6827:
2788:
Hodgon DC, Gospodarowicz MK (2007). "Clinical Evaluation and Staging of Hodgkin Lymphoma". In Hoppe RT, Mauch PT, Armitage JO, Diehl V, Weiss LM (eds.).
6961:
3356:"Aberrant expression of the Th2 cytokine IL-21 in Hodgkin lymphoma cells regulates STAT3 signaling and attracts Treg cells via regulation of MIP-3alpha"
6012:
5568:
7608:
2131:
1761:
1614:
and WS Greenfield first described the microscopic characteristics of Hodgkin lymphoma in 1872 and 1878, respectively. In 1898 and 1902, respectively,
1593:
7062:
6860:
6187:
5374:
1608:
entitled "Cases of enlargement of the lymphatic glands and spleen", in which he named the illness "Hodgkin's disease" in honor of his predecessor.
7486:
7160:
6714:
6418:
combines a biography of the American radiation oncologist (1918–84) with a history of the lymphatic cancer whose treatment he helped to transform.
1699:
409:
286:
151:
4545:
Estcourt LJ, Stanworth SJ, Doree C, Hopewell S, Trivella M, Murphy MF, et al. (Cochrane Haematological Malignancies Group) (November 2015).
3050:
1085:. Developed in Italy in the 1970s, the ABVD treatment typically takes between six and eight months, although longer treatments may be required.
628:
Is a rare subtype, composed of large numbers of often pleomorphic RS cells with only few reactive lymphocytes which may easily be confused with
328:) are most frequently involved (80–90% of the time, on average). The lymph nodes of the chest are often affected, and these may be noticed on a
293:. For those under the age of 20, rates of survival are 97%. Radiation and some chemotherapy drugs, however, increase the risk of other cancers,
7333:
5884:
7152:
6703:
6403:
5931:
5485:
5451:
5234:
4978:
3025:
2797:
2744:
2373:
776:
for staging. On the PET scan, sites involved with lymphoma light up very brightly enabling accurate and reproducible imaging. In the past, a
4785:"Decreased Prognostic Value of International Prognostic Score in Chinese Advanced Hodgkin Lymphoma Patients Treated in the Contemporary Era"
7598:
7481:
6113:
5593:
4643:
Knips L, Bergenthal N, Streckmann F, Monsef I, Elter T, Skoetz N, et al. (Cochrane Haematological Malignancies Group) (January 2019).
5135:
5491:
2726:
2379:
1814:. In 2010, aged 38, Hall announced he was undergoing treatment for Hodgkin lymphoma; within two years, the disease was in full remission.
7437:
7057:
6855:
6739:
6214:
5356:
2166:
1898:
1671:
6446:
6428:
5441:
5225:
Hellman S (2007). "Brief Consideration of Thomas Hodgkin and His Times". In Hoppe RT, Mauch PT, Armitage JO, Diehl V, Weiss LM (eds.).
3711:"Interim PET-results for prognosis in adults with Hodgkin lymphoma: a systematic review and meta-analysis of prognostic factor studies"
7328:
5910:
5847:
5826:
4886:
Biggi A, Gallamini A, Chauvie S, Hutchings M, Kostakoglu L, Gregianin M, Meignan M, Malkowski B, Hofman MS, Barrington SF (May 2013).
4113:
1788:, announced that he was diagnosed with Hodgkin lymphoma in a video he released on 19 May 2023. Green would announce his entrance into
6280:
3807:
Perri F, Della Vittoria Scarpati G, Buonerba C, Di Lorenzo G, Longo F, Muto P, Schiavone C, Sandomenico F, Caponigro F (2013-05-10).
1764:. Diagnosed in June 2014 at the age of 23. Continued to play until becoming too ill due to chemotherapy. Made recovery in early 2015.
6626:
6072:
5804:
1664:, co-founder of Microsoft was diagnosed with Hodgkin lymphoma in 1982. He later died from non-Hodgkin lymphoma, on October 15, 2018.
1625:
Tissue specimens from Hodgkin's seven cases were preserved at Guy's Hospital. Nearly 100 years after Hodgkin's initial publication,
1592:
Hodgkin's report on the seven cases, entitled "On some morbid appearances of the absorbent glands and spleen", was presented to the
976:
Hodgkin lymphoma can be sub-classified by histological type. The cell histology in Hodgkin lymphoma is not as important as it is in
1391:
7289:
5511:
4970:
1849:
1725:
788:
3907:
Edwards-Bennett SM, Jacks LM, Moskowitz CH, Wu EJ, Zhang Z, Noy A, Portlock CS, Straus DJ, Zelenetz AD, Yahalom J (March 2010).
3354:
Lamprecht B, Kreher S, Anagnostopoulos I, Jöhrens K, Monteleone G, Jundt F, Stein H, Janz M, Dörken B, Mathas S (October 2008).
2897:
1589:. Carswell's report of the seventh case was accompanied by numerous illustrations that aided early descriptions of the disease.
1286:
In childhood cases of Hodgkin lymphoma, long-term endocrine adverse effects are a major concern, mainly gonadal dysfunction and
1004:
alone. People of any stage with a large mass in the chest are usually treated with combined chemotherapy and radiation therapy.
953:
is distributed close to the nuclear membrane). Almost all of these cells have an increased copy number of chromosome 9p/9p24.1.
3909:"Stanford V program for locally extensive and advanced Hodgkin lymphoma: the Memorial Sloan-Kettering Cancer Center experience"
2654:
1960:
1254:
1622:
independently described the cytogenetic features of the malignant cells of Hodgkin lymphoma, now called Reed–Sternberg cells.
7519:
7511:
7370:
7248:
7187:
7173:
7067:
7008:
6845:
6771:
5002:
2234:
1368:
980:: the treatment and prognosis in classic Hodgkin lymphoma usually depends on the stage of disease rather than the histotype.
633:
5629:
1577:, London, Hodgkin studied seven people with painless lymph node enlargement. Of the seven cases, two were under the care of
731:. Due to these differences, among others, NLPHL is often treated differently from classic Hodgkin lymphoma, including using
5418:
4744:"A prognostic score for advanced Hodgkin's disease. International Prognostic Factors Project on Advanced Hodgkin's Disease"
1519:
infection. In contrast to many other lymphomas associated with HIV infection it occurs most commonly in people with higher
443:
May present with airway obstruction, pleural/pericardial effusion, hepatocellular dysfunction, or bone-marrow infiltration.
7567:
7477:
7427:
7323:
7052:
6836:
2498:
Rezk SA, Zhao X, Weiss LM (September 2018). "Epstein-Barr virus (EBV)-associated lymphoid proliferations, a 2018 update".
1973:, United States Senator from Pennsylvania (1981–2011), diagnosed in 2005. He later died from non-Hodgkin lymphoma in 2012.
1619:
1586:
2848:
Audard V, Zhang SY, Copie-Bergman C, Rucker-Martin C, Ory V, Candelier M, Baia M, Lang P, Pawlak A, Sahali D (May 2010).
2007:, American professional wrestler, reported to be ill with diagnosis from June 2022, completed treatment February 17, 2023
960:
Hodgkin cell (atypical mononuclear RSC) is a variant of RS cell, which has the same characteristics but is mononucleated.
795:
Stage I is involvement of a single lymph node region (I) (mostly the cervical region) or single extralymphatic site (Ie);
7459:
7365:
7348:
7156:
6710:
6619:
6336:
4402:
2187:
765:
461:
266:(EBV) and these are generally the classic form. Other risk factors include a family history of the condition and having
5726:
4935:
1319:
for those people with a favorable prognosis (FFP) was 98%, while that for people with worse outlooks was at least 85%.
7400:
7273:
6979:
6099:
629:
606:
Is a rare subtype, show many features which may cause diagnostic confusion with nodular lymphocyte predominant B-cell
405:
335:
Systemic symptoms: About one-third of people with Hodgkin disease may also present with systemic symptoms, including:
325:
5960:
4693:
Kluin-Nelemans JC, Viseu F, Baars JW, Poortmans P, Lugtenburg PJ, Carrie C, Jaubert J, Henry-Amar M (November 2007).
1246:
and the disease is a different entity in older people where different considerations enter into treatment decisions.
945:+/− immunophenotype. In approximately 50% of cases, the Reed–Sternberg cells are infected by the Epstein–Barr virus.
1557:
772:(MRI) scans of the chest, abdomen and pelvis, and usually a bone marrow biopsy. PET scan is now used instead of the
7315:
1825:
1578:
769:
5156:
900:
7593:
7203:
7044:
6966:
6450:
6395:
4008:
Ekstrand BC, Lucas JB, Horwitz SM, Fan Z, Breslin S, Hoppe RT, Natkunam Y, Bartlett NL, Horning SJ (2003-06-01).
1932:
1685:
997:
5542:
3597:"Genomic analyses of flow-sorted Hodgkin Reed-Sternberg cells reveal complementary mechanisms of immune evasion"
1967:, announced in August 2015 that he was diagnosed with Hodgkin's disease. He died of the disease in October 2015.
669:
7405:
7233:
6526:
6135:
1679:
1649:
1495:
1001:
6871:
5674:
1629:
reexamination confirmed Hodgkin lymphoma in only three of seven of these people. The remaining cases included
1290:. Gonadal dysfunction seems to be the most severe endocrine long-term effect, especially after treatment with
930:
228:
4783:
Wang Q, Qin Y, Kang SY, He XH, Liu P, Yang S, Zhou SY, Zhang CG, Gui L, Yang JL, Sun Y, Shi YK (2016-12-05).
4472:
van Dorp W, van Beek RD, Laven JS, Pieters R, de Muinck Keizer-Schrama SM, van den Heuvel-Eibrink MM (2011).
6441:
6016:
5572:
3197:
2123:
1316:
1262:
290:
167:
7422:
6973:
709:) are occasionally expressed. However, this may be an artifact of the ambiguity inherent in the diagnosis.
263:
117:
7299:
7278:
7192:
5989:
2970:
McKay P, Fielding P, Gallop-Evans E, Hall GW, Lambert J, Leach M, Marafioti T, McNamara C (January 2016).
1964:
1375:
by more than one third, or the presence of a nodal mass measuring more than 10 cm in any dimension.)
1359:
1000:
compared with chemotherapy treatment alone. People with later disease (III, IVA, or IVB) are treated with
969:"Popcorn" RSC (lympho-histiocytic variant) is a small cell, with a very lobulated nucleus, small nucleoli.
498:
437:
5698:
427:
231:(RS cells) are present in the patient's lymph nodes. The condition was named after the English physician
7603:
7431:
7021:
6915:
3486:
889:
6994:
6817:
3760:"Chemotherapy alone versus chemotherapy plus radiotherapy for adults with early stage Hodgkin lymphoma"
1831:
Daniel Hauser, whose mother fled with him in 2009 in order to prevent him from undergoing chemotherapy.
1757:
787:
On the basis of this staging, the person will be classified according to a staging classification (the
320:. The nodes may also feel rubbery and swollen when examined. The nodes of the neck, armpits and groin (
5335:
3020:(Revised 4th ed.). Lyon: International Agency for Research on Cancer, World Health Organization.
7228:
6840:
6751:
5876:
5731:
5229:(2nd ed.). Philadelphia: Wolters Kluwer Health/Lippincott Williams & Wilkins. pp. 3–6.
3305:
Tzankov A, Bourgau C, Kaiser A, Zimpfer A, Maurer R, Pileri SA, Went P, Dirnhofer S (December 2005).
1996:
1982:
1795:
1789:
1630:
1499:
1491:
1069:
is the standard treatment of Hodgkin's disease in the US. The abbreviation stands for the four drugs
1066:
977:
805:
Stage III is involvement of lymph node regions on both sides of the diaphragm, which may include the
735:
in combination with AVBD chemotherapy, though individual cases vary and clinical trials are ongoing.
607:
494:
490:
321:
2972:"Guidelines for the investigation and management of nodular lymphocyte predominant Hodgkin lymphoma"
2010:
Rick Czaplewski, Author Better Dirty Than Done, Motivational Speaker, 2009 Boston Marathon Finisher.
7028:
6812:
6782:
6507:
4178:"Hodgkin lymphoma: 2014 update on diagnosis, risk-stratification, and management: Hodgkin lymphoma"
1936:
1860:
1715:
1010:
799:
761:
343:
52:
7492:
6077:
4917:
4724:
4274:
Eichenauer D, Engert A, André M, Federico M, Illidge T, Hutchings M, Ladetto M (September 2014).
4207:
4158:
4039:
3948:
3889:
3467:
3336:
3176:
3127:
3099:
3080:
2523:
2480:
2088:
1810:
1675:
1287:
433:
397:
362:
88:
5597:
1904:
1853:. After three months of chemotherapy and one month of radiation, the cancer went into remission.
430:, or more simply "P-E fever". However, there is debate as to whether the P-E fever truly exists.
2923:"Feasibility of blood testing combined with PET-CT to screen for cancer and guide intervention"
7572:
7242:
7223:
7212:
7002:
6892:
6807:
6577:
6537:
6482:
6409:
6399:
5800:
5481:
5475:
5447:
5317:
5267:
5230:
5109:
5060:
4974:
4909:
4865:
4816:
4765:
4716:
4674:
4625:
4576:
4527:
4495:
4454:
4380:
4344:
4305:
4276:"Hodgkin's lymphoma: ESMO Clinical Practice Guidelines for diagnosis, treatment and follow-up"
4256:
4199:
4150:
4105:
4074:
4031:
3990:
3930:
3881:
3840:
3789:
3740:
3653:
3626:
3576:
3513:
3459:
3418:
3377:
3328:
3287:
3246:
3168:
3119:
3072:
3031:
3021:
2993:
2952:
2879:
2830:
2793:
2740:
2723:
2699:
2614:
2564:
2515:
2472:
2415:
2369:
2363:
2344:
2291:
2162:
2080:
2062:
1976:
1844:
1770:, Australian singer, songwriter, and actress. She was diagnosed in July 2003 at the age of 18.
1733:
1645:
1574:
1570:
1504:
992:
882:
533:
282:
147:
133:
128:
72:
6239:
372:; thus, presence of these indicate that the person's stage is, for example, 2B instead of 2A.
7342:
7121:
6611:
5617:
5516:
5307:
5259:
5099:
5091:
5050:
5042:
4899:
4855:
4847:
4806:
4796:
4755:
4706:
4664:
4656:
4615:
4607:
4566:
4558:
4519:
4485:
4444:
4436:
4372:
4336:
4295:
4287:
4246:
4238:
4189:
4140:
4066:
4021:
3982:
3920:
3871:
3830:
3820:
3779:
3771:
3730:
3722:
3679:
3616:
3608:
3566:
3449:
3408:
3367:
3318:
3277:
3236:
3158:
3111:
3062:
2983:
2942:
2934:
2869:
2861:
2822:
2689:
2604:
2554:
2507:
2464:
2407:
2334:
2326:
2281:
2273:
2070:
2052:
2044:
2004:
1940:
1922:
1821:
1739:
1611:
1569:, although Hodgkin noted that perhaps an earlier reference to the condition was provided by
1403:
1342:
1291:
1194:
329:
220:
5855:
5818:
4093:
7115:
7110:
6919:
6803:
6669:
6664:
5396:
2730:
2031:
Lozano R, Naghavi M, Foreman K, Lim S, Shibuya K, Aboyans V, et al. (December 2012).
1801:
1719:
1689:
1034:
313:
248:
105:
4057:
Borchmann S, Engert A, Böll B (September 2018). "Hodgkin lymphoma in elderly patients".
2075:
632:. Many cases previously classified within this category would now be reclassified under
7562:
6059:
5312:
5295:
5104:
5079:
5055:
5030:
4860:
4835:
4811:
4784:
4669:
4644:
4620:
4595:
4571:
4546:
4449:
4424:
4251:
3835:
3808:
3784:
3759:
3735:
3710:
3621:
3596:
3571:
3554:
3051:"From Hodgkin disease to Hodgkin lymphoma: biologic insights and therapeutic potential"
2947:
2922:
2874:
2849:
2694:
2677:
2339:
2314:
2286:
2261:
1926:
1882:
1817:
1745:
1626:
1615:
1582:
1566:
1395:
777:
748:
713:
661:
644:
618:
592:
569:
232:
196:
6437:
5263:
5078:
Biggar RJ, Jaffe ES, Goedert JJ, Chaturvedi A, Pfeiffer R, Engels EA (December 2006).
4474:"Long-term endocrine side effects of childhood Hodgkin's lymphoma treatment: a review"
4145:
4128:
2763:
2330:
2277:
2048:
426:
Cyclical fever: People may also present with a cyclical high-grade fever known as the
7587:
7469:
7168:
7077:
7033:
6850:
6724:
3612:
3163:
3146:
3115:
2057:
1970:
1952:
1918:
1914:
1894:
1888:
1876:
1856:
1805:
1767:
1705:
1695:
413:
294:
155:
6599:
6512:
6263:"Brandon Tartikoff, Former NBC Executive Who Transformed TV in the 80's, Dies at 48"
5819:"Cancer-Free Michael C. Hall Back to Work on Dexter—Health, Dexter, Michael C. Hall"
4728:
4211:
4162:
4043:
3893:
3471:
3340:
3131:
2646:
2527:
2484:
681:
7072:
6734:
6588:
4994:
4921:
4660:
4611:
4562:
4523:
3775:
3726:
3180:
3084:
2436:
Hodgkin T (1832). "On some morbid experiences of the absorbent glands and spleen".
2226:
2092:
1866:
1777:
1751:
1729:
1634:
1604:
1279:
1198:
1189:
1179:
1109:
1051:
773:
554:
465:
460:
are also performed to assess function of major organs and safety for chemotherapy.
387:
377:
278:
240:
143:
97:
5528:
4425:"Strategies for optimizing the response of cancer and normal tissues to radiation"
3264:
Bräuninger A, Schmitz R, Bechtel D, Renné C, Hansmann ML, Küppers R (April 2006).
2511:
2468:
1869:(1917–1950), Romanian classical pianist and composer. Diagnosed in 1947, received
923:
798:
Stage II is involvement of two or more lymph node regions on the same side of the
17:
6531:
6161:
5095:
4376:
4070:
4010:"Rituximab in lymphocyte-predominant Hodgkin disease: results of a phase 2 trial"
3438:"Observer variation in interpreting 18F-FDG PET/CT findings for lymphoma staging"
3413:
3396:
3372:
3355:
2865:
2609:
2592:
400:: The enlargement of both the liver and spleen can be caused by the same disease.
6746:
6572:
5954:
5952:
5189:
4760:
4743:
2826:
1834:
1709:
1372:
1184:
1172:
1167:
1163:
1158:
1124:
1119:
1114:
1082:
1078:
550:
546:
349:
317:
316:: The most common symptom of Hodgkin is the painless enlargement of one or more
244:
112:
101:
64:
6188:"Chip Roy's plan to get Washington out of the way includes going there himself"
5520:
4645:"Aerobic physical exercise for adult patients with haematological malignancies"
4026:
4009:
3986:
3645:
3505:
3266:"Molecular biology of Hodgkin's and Reed/Sternberg cells in Hodgkin's lymphoma"
3067:
817:
adding "S" to the stage. The inclusion of "bulky disease" is signified by "X".
6642:
6594:
6542:
6281:"Portuguese midfielder Bernardo Tengarrinha diagnosed with linfoma de Hodgkin"
5775:
5747:
5506:
5250:
Dawson PJ (December 1999). "The original illustrations of Hodgkin's disease".
4904:
4887:
3758:
Blank O, von Tresckow B, Monsef I, Specht L, Engert A, Skoetz N (April 2017).
3537:
3454:
3437:
3323:
3306:
3241:
3224:
3035:
1992:
1956:
1908:
1773:
1667:
1661:
1644:
Hodgkin lymphoma was one of the first cancers to be treated successfully with
1336:
1230:
1225:
1153:
1089:
1070:
1047:
1020:
915:
904:
781:
656:
639:
613:
600:
587:
564:
502:
457:
436:
can occur in individuals with Hodgkin lymphoma and is most commonly caused by
369:
224:
77:
60:
6413:
5031:"Epidemiological Overview of Hodgkin Lymphoma across the Mediterranean Basin"
4801:
4695:"Chemotherapy plus involved-field radiation in early-stage Hodgkin's disease"
972:"Mummy" RSC has a compact nucleus with no nucleolus and basophilic cytoplasm.
6583:
6548:
6497:
4851:
4490:
4473:
4291:
4094:"Hodgkin's lymphoma in the elderly: a different disease in patients over 60"
3925:
3908:
3876:
3859:
2938:
2066:
1870:
1840:
1785:
1399:
1239:
1214:
1209:
1146:
1141:
1136:
1074:
1039:
991:
People with early stage disease (IA or IIA) can be treated effectively with
950:
802:(II) or of one lymph node region and a contiguous extralymphatic site (IIe);
753:
732:
477:
therefore, the clinical behaviour and presentation of the two types differ.
420:
368:
Systemic symptoms such as fever, night sweats, and weight loss are known as
162:
5271:
5113:
5064:
5046:
4913:
4869:
4820:
4720:
4678:
4629:
4580:
4531:
4499:
4458:
4384:
4348:
4309:
4275:
4260:
4203:
4154:
4109:
4078:
4035:
3994:
3934:
3885:
3844:
3809:"Combined chemo-radiotherapy in locally advanced nasopharyngeal carcinomas"
3793:
3744:
3657:
3630:
3580:
3517:
3463:
3422:
3381:
3332:
3291:
3250:
3172:
3123:
3076:
2997:
2956:
2883:
2618:
2568:
2519:
2476:
2419:
2348:
2295:
2084:
545:
showing scattered lacunar classic RS cells set in a background of reactive
5321:
4769:
3825:
2834:
2703:
2411:
1326:
The adverse prognostic factors identified in the international study are:
812:
Stage IV is disseminated involvement of one or more extralymphatic organs.
394:, due to liver involvement, is infrequent in people with Hodgkin lymphoma.
7557:
7385:
7096:
6659:
6646:
4711:
4694:
1986:
1946:
1804:(born February 1, 1971), American actor, best known for his lead role as
1638:
1596:
in January 1832 and was subsequently published in the society's journal,
1275:
338:
267:
258:
The two major types of Hodgkin lymphoma are classic Hodgkin lymphoma and
212:
121:
81:
5647:
4324:
4300:
3436:
Hofman MS, Smeeton NC, Rankin SC, Nunan T, O'Doherty MJ (October 2009).
809:(IIIs) or limited contiguous extralymphatic organ or site (IIIe, IIIes);
5752:
5029:
Salati M, Cesaretti M, Macchia M, Mistiri ME, Federico M (2014-06-29).
4340:
2559:
2542:
2001:
reality television series. Zohn was diagnosed twice (in 2009 and 2011).
1353:
1261:
directed above the diaphragm to the neck, chest or underarms is called
1131:
1096:
1043:
1025:
6465:
4226:
4194:
4177:
3282:
3265:
3223:
Küppers R, Schwering I, Bräuninger A, Rajewsky K, Hansmann ML (2002).
2988:
2971:
1925:, diagnosed in May 2008 while signed as a minor league player for the
7105:
6492:
6477:
6432:
5546:
5296:"Comments on the anniversary of the description of Hodgkin's disease"
4242:
2792:(2nd ed.). Lippincott Williams & Wilkins. pp. 123–132.
1979:, American television executive, diagnosed around 1974, died in 1997.
1781:
1688:, Welsh professional footballer, diagnosed in 2021 while playing for
806:
698:
690:
674:
521:
505:
453:
381:
352:
of at least 10% of the person's total body mass in six months or less
216:
191:
5703:
4440:
3018:
WHO classification of tumours of haematopoietic and lymphoid tissues
2032:
1828:, died on October 25, 2002, after being diagnosed earlier that year.
1515:
The number of cases of Hodgkin lymphoma is increased in people with
743:
The staging is the same for both Hodgkin and non-Hodgkin lymphomas.
6928:
6793:
6777:
5669:
1702:" (c)1936, Born 1888, Maryville, MO, died 1955, Forest Hills,NY.
1556:
1390:
918:
showing a "popcorn cell", the Reed–Sternberg cell variant seen in
910:
899:
757:
680:
668:
539:
526:
391:
356:
252:
236:
93:
6553:
3553:
Vockerodt M, Cader FZ, Shannon-Lowe C, Murray P (December 2014).
3487:"Table 4. Ann Arbor Staging Classification for Hodgkin Lymphomaa"
3307:"Rare expression of T-cell markers in classic Hodgkin's lymphoma"
3201:
7391:
7285:
7264:
7182:
6924:
6899:
6879:
6875:
6762:
6680:
6675:
6362:
6114:"Nikola Pokrivač: Nema predaje, sve ću podnijeti za ženu i kćer"
5932:"Comedian Sean Kent laughs off hecklers, cancer to stay on road"
5080:"Hodgkin lymphoma and immunodeficiency in persons with HIV/AIDS"
1348:
1101:
1062:
1015:
942:
938:
934:
728:
694:
6615:
6100:"Denver health care activist speaking at Democratic convention"
5594:"Childhood Cancer Research Program—Michael Cuccione Foundation"
5545:. NBC News. Associated Press. September 5, 2006. Archived from
1863:
and founder of the Mario Lemieux Foundation, diagnosed in 1993.
1093:
radiotherapy, diverging from the original Stanford V protocol.
7131:
7126:
7016:
6215:"Minnesota Timberwolves Say Head Coach Flip Saunders Has Died"
5985:
1520:
1516:
706:
702:
309:
People with Hodgkin lymphoma may present with these symptoms:
5877:"Minnesota: Evaluation Ordered for a 13-Year-Old With Cancer"
5443:
Book: Words that Shaped our World, ref to Dale Carnagie+death
4834:
Ali S, Basit A, Kazmi AS, Sidhu A, Badar F, Hameed A (2016).
4365:
International Journal of Radiation Oncology, Biology, Physics
3192:
3190:
2398:
Armitage JO (August 2010). "Early-stage Hodgkin's lymphoma".
1879:, English snooker player, diagnosed in 2008 at the age of 16.
1873:
treatment in 1949; died from a burst abscess on his one lung.
1561:
Photograph of Hodgkin's disease from a 1938 medical textbook
7269:
Non-mycosis fungoides CD30− cutaneous large T-cell lymphoma
5375:"Bournemouth midfielder David Brooks diagnosed with cancer"
5035:
Mediterranean Journal of Hematology and Infectious Diseases
4325:"Brentuximab vedotin: An anti-CD30 antibody–drug conjugate"
1754:, British composer, was diagnosed in 1951 and died in 1956.
1253:
For Hodgkin lymphomas, radiation oncologists typically use
3147:"Epstein-Barr virus-associated Hodgkin's lymphoma: Review"
3098:
Gobbi PG, Ferreri AJ, Ponzoni M, Levis A (February 2013).
2188:"Adult Hodgkin Lymphoma Treatment (PDQ) – Patient Version"
2124:"Adult Hodgkin Lymphoma Treatment (PDQ) – Patient Version"
1995:, American professional soccer player and a winner of the
1565:
Hodgkin lymphoma was first described in an 1832 report by
456:(usually excisional biopsy with microscopic examination).
272:
Epstein–Barr virus-associated lymphoproliferative diseases
2898:"Hodgkin Lymphoma Diagnosis | Tests for Hodgkin Lymphoma"
2541:
Ward E, DeSantis C, Robbins A, Kohler B, Jemal A (2014).
610:(B-NHL). This form also has the most favorable prognosis.
3485:((PDQ Pediatric Treatment Editorial Board (2022-04-08).
5336:"Microsoft co-founder Paul Allen diagnosed with cancer"
4999:
NCI Surveillance, Epidemiology, and End Results Program
4965:
Mauch P, Armitage J, Diehl V, Hoppe R, Weiss L (1999).
3555:"Epstein-Barr virus and the origin of Hodgkin lymphoma"
2313:
CO, Kassebaum NJ, Kinfu Y, Kulikoff XR (October 2016).
1939:. Diagnosed in March 2010 while he was a coach for the
1897:, health care activist diagnosed in 2017, spoke at the
235:, who first described it in 1832. Symptoms may include
3952:
1885:, Indian film actress and producer, diagnosed in 2010.
746:
After Hodgkin lymphoma is diagnosed, a person will be
6073:"FILM; An Italian Satirist Takes a Very Serious Turn"
1648:
and, later, it was one of the first to be treated by
262:. About half of cases of Hodgkin lymphoma are due to
6455:
5799:. 1st Ed. Praha: The World Circle Foundation, 2000.
3049:
Re D, Thomas RK, Behringer K, Diehl V (2005-06-15).
2260:
Kassebaum NJ, Kawashima T, Kemmer L (October 2016).
538:
Is the most common subtype and is composed of large
7545:
7510:
7468:
7450:
7414:
7384:
7357:
7312:
7257:
7211:
7202:
7142:
7104:
7095:
7043:
6953:
6914:
6870:
6792:
6761:
6723:
6702:
6691:
6658:
6563:
6459:
2758:
2756:
190:
182:
174:
161:
139:
127:
111:
87:
71:
42:
37:
7339:Peripheral T-cell lymphoma not otherwise specified
2543:"Childhood and adolescent cancer statistics, 2014"
1847:and actor. Was diagnosed in 2002 while writing on
7161:Precursor T acute lymphoblastic leukemia/lymphoma
6715:Precursor B acute lymphoblastic leukemia/lymphoma
5596:. www.childhoodcancerresearch.org. Archived from
6307:"Ethan Zohn is a survivor in more ways than one"
2457:Critical Reviews in Clinical Laboratory Sciences
2161:. World Health Organization. 2014. Chapter 2.4.
1798:, Czechoslovak theatre actor, poet, and composer
1748:, American tennis player, was diagnosed in 2014.
677:showing Hodgkin lymphoma, mixed-cellularity type
6905:Nodular lymphocyte predominant Hodgkin lymphoma
6392:Henry Kaplan and the Story of Hodgkin's Disease
6162:"'04 Red Sox hero Roberts treated for lymphoma"
6039:"Cancer fight gives Lisowski new angle on life"
4881:
4879:
4225:Küppers R, Engert A, Hansmann ML (2012-10-01).
3652:, Treasure Island (FL): StatPearls Publishing,
3542:. The Publishing House of the Romanian Academy.
3512:, Treasure Island (FL): StatPearls Publishing,
2719:
2717:
2715:
2713:
2182:
2180:
2178:
920:nodular lymphocyte predominant Hodgkin lymphoma
725:Nodular lymphocyte predominant Hodgkin lymphoma
487:nodular lymphocyte predominant Hodgkin lymphoma
297:, or lung disease over the subsequent decades.
260:nodular lymphocyte-predominant Hodgkin lymphoma
255:. Persons affected may feel tired or be itchy.
5543:"Teen, court reach agreement over cancer care"
5419:"Dale Carnagie page: strategies for influence"
4323:Bradley AM, Devine M, DeRemer D (2013-04-01).
4104:(8): 982–90, discussion 990, 996, 998 passim.
2431:
2429:
1760:, Icelandic football player and member of the
966:Pleomorphic RSC has multiple irregular nuclei.
689:For the other forms, although the traditional
7295:Secondary cutaneous CD30+ large-cell lymphoma
6627:
6337:"Richard Holliday completes cancer treatment"
5961:"Funnyman Sean Kent winning fight vs. cancer"
5289:
5287:
5285:
5283:
5281:
2118:
2116:
2114:
2112:
2110:
2108:
2106:
2104:
2102:
2026:
2024:
1708:, Egyptologist and discoverer of the Tomb of
1573:in 1666. While occupied as museum curator at
1038:. The abbreviation stands for the four drugs
756:, a physical examination, blood tests, chest
8:
6985:Post-transplant lymphoproliferative disorder
6940:immunoproliferative immunoglobulin disorders
5668:Ásta Sigrún Magnúsdóttir (16 October 2015).
5515:(online ed.). Oxford University Press.
5220:
5218:
5216:
5214:
5212:
5210:
3539:TUMORS OF HEMATOPOIETIC AND LYMPHOID TISSUES
2813:Hilson AJ (July 1995). "Pel-Ebstein fever".
2678:"Alcohol-related pain and Hodgkin's disease"
2254:
2252:
2153:
2151:
2149:
1837:, Australian actress, was diagnosed in 2014.
251:occur in the neck, under the arm, or in the
7498:Diffuse infiltrative lymphocytosis syndrome
5480:. Tauris Parke Paperbacks. pp. 454–5.
5300:Journal of the National Medical Association
4649:The Cochrane Database of Systematic Reviews
4600:The Cochrane Database of Systematic Reviews
4551:The Cochrane Database of Systematic Reviews
4516:The Cochrane Database of Systematic Reviews
4401:. RTanswers.com. 2010-12-03. Archived from
3764:The Cochrane Database of Systematic Reviews
3715:The Cochrane Database of Systematic Reviews
3397:"Hodgkin Lymphoma: Diagnosis and Treatment"
3145:Gandhi MK, Tellam JT, Khanna R (May 2004).
2593:"Hodgkin Lymphoma: Diagnosis and Treatment"
2307:
2305:
1859:, Hall of Fame NHL player, co-owner of the
1498:increases with age, Hodgkin lymphoma has a
7537:Jessner lymphocytic infiltrate of the skin
7208:
7139:
7101:
7083:Primary cutaneous follicle center lymphoma
6828:Primary cutaneous follicle center lymphoma
6699:
6688:
6655:
6634:
6620:
6612:
6456:
6240:"Specter diagnosed with Hodgkin's disease"
4936:"WHO Disease and injury country estimates"
4329:American Journal of Health-System Pharmacy
2221:
2219:
2217:
2215:
2213:
557:with varying degrees of collagen fibrosis/
412:is high enough for it to be regarded as a
51:
34:
5907:"Tessa James reveals she is in remission"
5569:"James Conner Announces Cancer Diagnosis"
5311:
5103:
5054:
4903:
4859:
4810:
4800:
4759:
4710:
4668:
4619:
4570:
4489:
4448:
4299:
4250:
4193:
4144:
4025:
3924:
3875:
3834:
3824:
3783:
3734:
3674:
3672:
3620:
3570:
3453:
3412:
3371:
3322:
3281:
3240:
3162:
3066:
2987:
2946:
2873:
2693:
2608:
2558:
2393:
2391:
2389:
2338:
2285:
2227:"SEER Stat Fact Sheets: Hodgkin Lymphoma"
2074:
2056:
1594:Medical and Chirurgical Society of London
1032:The original treatment for Hodgkin's was
497:and the composition of the reactive cell
7063:Primary cutaneous marginal zone lymphoma
6861:Primary cutaneous marginal zone lymphoma
6136:"Emma: Anthony Rizzo's Indelible Impact"
5727:"Delta Goodrem Hospitalized With Cancer"
5440:Stovall J, Johnson K (6 February 2024).
4742:Hasenclever D, Diehl V (November 1998).
4423:Moding EJ, Kastan MB, Kirsch DG (2013).
4092:Klimm B, Diehl V, Engert A (July 2007).
3949:"Home | German Hodgkin Study Group"
1732:and 2014 ACC Player of the Year for the
1598:Medical-Chirurgical Society Transactions
1250:but still existing refractory patients.
1006:
511:
493:subtypes based upon Reed–Sternberg cell
7525:with bandlike and perivascular patterns
7487:Autoimmune lymphoproliferative syndrome
5909:. Yahoo! News Australia. Archived from
5512:Oxford Dictionary of National Biography
3104:Critical Reviews in Oncology/Hematology
2020:
1700:How to Win Friends and Influence People
819:
7334:Enteropathy-associated T-cell lymphoma
6142:from the original on 14 September 2015
5477:Howard Carter: The Path to Tutankhamun
4127:Townsend W, Linch D (September 2012).
2737:Cancer: A Comprehensive Clinical Guide
1712:, died in 1939 from Hodgkin's disease.
27:Type of blood and immune-system cancer
5184:
5182:
5024:
5022:
5020:
3703:
3701:
3011:
3009:
3007:
2640:
2638:
2636:
2634:
2632:
2630:
2628:
2586:
2584:
2582:
2580:
2578:
1371:, and bulky disease (widening of the
509:comparison in nodular sclerosing HL.
277:Hodgkin lymphoma may be treated with
46:Hodgkin's lymphoma, Hodgkin's disease
7:
7482:X-linked lymphoproliferative disease
5699:"Ótrúleg endurkoma eftir röð áfalla"
5697:Gunnar Birgisson (11 October 2020).
5167:from the original on 17 October 2014
5005:from the original on 17 October 2012
4840:Pakistan Journal of Medical Sciences
2768:The Lecturio Medical Concept Library
2368:(2nd ed.). Wiley. p. 195.
2237:from the original on 17 October 2012
1935:, MLB outfielder and manager of the
1406:per 100,000 inhabitants in 2004
485:Classic Hodgkin lymphoma (excluding
7438:Large granular lymphocytic leukemia
7058:Intravascular large B-cell lymphoma
5848:"Lionhearted—Death, Richard Harris"
5357:"Eric Berry has Hodgkin's lymphoma"
4748:The New England Journal of Medicine
4699:The New England Journal of Medicine
2815:The New England Journal of Medicine
2547:CA: A Cancer Journal for Clinicians
2400:The New England Journal of Medicine
1899:2020 Democratic National Convention
468:may be used instead of a PET scan.
219:originates from a specific type of
6013:"Dinu Lipatti: Prince of Pianists"
5883:. Associated Press. May 16, 2009.
3813:World Journal of Clinical Oncology
2657:from the original on June 28, 2009
1238:The common non-Hodgkin treatment,
25:
5992:from the original on 3 April 2013
5887:from the original on May 31, 2015
4995:"SEER Stat Fact Sheets: Leukemia"
4971:Lippincott Williams & Wilkins
4231:Journal of Clinical Investigation
3491:PDQ Cancer Information Summaries
2198:from the original on 28 July 2016
2134:from the original on 28 July 2016
489:) can be subclassified into four
7609:Diseases named after discoverers
6015:. markainley.com. Archived from
5636:from the original on 2016-01-12.
5630:"Victoria Duval battling cancer"
5494:from the original on 2017-09-10.
5397:"Dale Carnagie at Biography.com"
5363:from the original on 2015-03-08.
4116:from the original on 2009-05-12.
3613:10.1182/bloodadvances.2019001012
3164:10.1111/j.1365-2141.2004.04902.x
3116:10.1016/j.critrevonc.2012.07.002
2382:from the original on 2017-09-10.
1850:The Best Damn Sports Show Period
1698:, Public Speaker and author of "
907:of a classic Reed–Sternberg cell
858:
846:
834:
822:
789:Ann Arbor staging classification
291:survive for five years or longer
7290:CD30+ cutaneous T-cell lymphoma
6221:from the original on 2015-10-26
5959:Chandler R (28 November 2007).
5829:from the original on 2015-02-08
5774:vlogbrothers (25 August 2023),
4946:from the original on 2009-11-11
3270:International Journal of Cancer
3225:"Biology of Hodgkin's lymphoma"
2682:The Western Journal of Medicine
1776:, one of the cofounders of the
1762:Icelandic women's national team
1255:external beam radiation therapy
885:) a nodular aspect may appear.
7520:Cutaneous lymphoid hyperplasia
7512:Cutaneous lymphoid hyperplasia
7371:Adult T-cell leukemia/lymphoma
7249:Adult T-cell leukemia/lymphoma
7188:Anaplastic large-cell lymphoma
7068:Primary cutaneous immunocytoma
7009:Splenic marginal zone lymphoma
6313:. 18 June 2014. Archived from
5678:(in Icelandic). pp. 30–31
5252:Annals of Diagnostic Pathology
4661:10.1002/14651858.CD009075.pub3
4612:10.1002/14651858.CD009768.pub2
4563:10.1002/14651858.CD010983.pub2
4524:10.1002/14651858.CD004269.pub3
4429:Nature Reviews. Drug Discovery
4182:American Journal of Hematology
4129:"Hodgkin's lymphoma in adults"
3776:10.1002/14651858.CD007110.pub3
3727:10.1002/14651858.CD012643.pub3
3644:Aggarwal P, Limaiem F (2022),
3151:British Journal of Haematology
2976:British Journal of Haematology
1369:erythrocyte sedimentation rate
1042:(also known as chlormethine),
720:Nodular lymphocyte predominant
634:anaplastic large cell lymphoma
178:574,000 (affected during 2015)
1:
7568:Lymphoproliferative disorders
7478:Lymphoproliferative disorders
7428:Extranodal NK-T-cell lymphoma
7300:Lymphomatoid papulosis type A
7279:Lymphomatoid papulosis type B
7193:Lymphomatoid papulosis type A
7053:Diffuse large B-cell lymphoma
5670:"Vá, hvað get ég gert meira?"
5377:. Sky Sports. 13 October 2021
5264:10.1016/S1092-9134(99)80018-5
5157:"Hodgkin lymphoma statistics"
4146:10.1016/S0140-6736(12)60035-X
2512:10.1016/j.humpath.2018.05.020
2469:10.1080/10408363.2017.1422692
2331:10.1016/s0140-6736(16)31012-1
2278:10.1016/S0140-6736(16)31678-6
2049:10.1016/S0140-6736(12)61728-0
1891:, Italian actor and director.
1808:, in Showtime's crime series
1046:(also known as vincristine),
7460:Acute biphenotypic leukaemia
7349:Subcutaneous T-cell lymphoma
5746:vlogbrothers (19 May 2023).
5529:UK public library membership
5507:"Carter, Howard (1874–1939)"
5128:"Canadian Cancer Statistics"
5096:10.1182/blood-2006-05-024109
4377:10.1016/j.ijrobp.2013.05.005
4071:10.1097/CCO.0000000000000464
3864:Journal of Clinical Oncology
3504:Sapkota S, Shaikh H (2022),
3414:10.1016/j.mayocp.2015.07.005
3373:10.1182/blood-2008-01-134783
2866:10.1182/blood-2009-11-251132
2610:10.1016/j.mayocp.2015.07.005
1820:, Irish actor who portrayed
1496:number of new cases per year
766:positron emission tomography
582:Epstein-Barr virus infection
462:Positron emission tomography
7599:Infectious causes of cancer
7401:Aggressive NK-cell leukemia
7274:Pleomorphic T-cell lymphoma
6980:Lymphomatoid granulomatosis
6361:Czaplewski R (2023-09-30).
6186:Chasnoff B (May 13, 2018).
6138:. CBS Chicago. 8 May 2014.
4892:Journal of Nuclear Medicine
4761:10.1056/NEJM199811193392104
3442:Journal of Nuclear Medicine
2827:10.1056/NEJM199507063330118
2591:Ansell SM (November 2015).
630:diffuse large cell lymphoma
7625:
6335:Thompson A (17 Feb 2023).
6116:(in Croatian). 8 June 2017
6102:. Denver Post. 2020-08-18.
5986:"Mario Lemieux Foundation"
4027:10.1182/blood-2002-08-2644
3987:10.1016/j.ctrv.2010.11.005
3951:. Ghsg.org. Archived from
3198:"HMDS: Hodgkin's Lymphoma"
3068:10.1182/blood-2004-12-4750
3016:Swerdlow SH (2017-09-18).
2362:Bower M, Waxman J (2011).
770:magnetic resonance imaging
63:showing Hodgkin lymphoma (
6654:
6451:National Cancer Institute
6396:Stanford University Press
5965:www.tahoedailytribune.com
5294:Geller SA (August 1984).
4940:World Health Organisation
4905:10.2967/jnumed.112.110890
4478:Human Reproduction Update
3559:Chinese Journal of Cancer
3536:Baba AI, Câtoi C (2007).
3455:10.2967/jnumed.109.064121
3324:10.1038/modpathol.3800473
2651:Merck Manual Professional
2645:Portlock CS (July 2008).
1716:Starchild Abraham Cherrix
998:progression-free survival
791:scheme is a common one):
576:Mixed-cellularity subtype
410:positive predictive value
408:. On the other hand, its
287:stem-cell transplantation
59:
50:
7553:Hematological malignancy
7406:Blastic NK cell lymphoma
7234:Granulomatous slack skin
6990:Classic Hodgkin lymphoma
6889:Classic Hodgkin lymphoma
6192:San Antonio Express-News
5648:"Gerald Finzi biography"
4802:10.4103/0366-6999.194661
3975:Cancer Treatment Reviews
2739:. Taylor & Francis.
2676:Bobrove AM (June 1983).
2159:World Cancer Report 2014
1680:National Football League
1650:combination chemotherapy
1294:or pelvic radiotherapy.
1002:combination chemotherapy
865:Stage 4 Hodgkin lymphoma
853:Stage 3 Hodgkin lymphoma
841:Stage 2 Hodgkin lymphoma
829:Stage 1 Hodgkin lymphoma
6442:American Cancer Society
6261:Carter B (1997-08-28).
6242:. CNN. 16 February 2005
4852:10.12669/pjms.326.11080
4789:Chinese Medical Journal
4176:Ansell SM (July 2014).
3877:10.1200/JCO.2005.02.907
3401:Mayo Clinic Proceedings
3242:10.1093/annonc/13.S1.11
2939:10.1126/science.abb9601
2597:Mayo Clinic Proceedings
2365:Lecture Notes: Oncology
1784:and production company
1317:five-year survival rate
227:, where multinucleated
168:Five-year survival rate
6367:www.rickczaplewski.com
6071:Laura Winters (2002).
5936:Columbia Daily Tribune
5817:Huver S (2010-07-23).
5521:10.1093/ref:odnb/32312
5047:10.4084/mjhid.2014.048
3646:"Reed Sternberg Cells"
3506:"Non-Hodgkin Lymphoma"
2735:John Kearsley (1998).
1965:Minnesota Timberwolves
1562:
1487:
1345:< 600/μL or < 8%
1263:mantle field radiation
926:
908:
712:Hodgkin cells produce
686:
678:
438:minimal change disease
7432:Angiocentric lymphoma
7022:AIDS-related lymphoma
6846:Splenic marginal zone
5748:"So, I've got cancer"
4491:10.1093/humupd/dmr038
4292:10.1093/annonc/mdu181
3926:10.1093/annonc/mdp337
3826:10.5306/wjco.v4.i2.47
2412:10.1056/NEJMra1003733
2058:10536/DRO/DU:30050819
1560:
1394:
914:
903:
890:fibrin ring granuloma
684:
672:
534:Nodular sclerosing HL
390:: Enlargement of the
380:: Enlargement of the
7530:with nodular pattern
7229:Pagetoid reticulosis
6841:marginal zone B-cell
6011:Mark Ainley (2002).
5359:. ESPN. 2014-12-08.
4712:10.1056/NEJMoa064601
2325:(10053): 1459–1544.
2272:(10053): 1545–1602.
1983:Bernardo Tengarrinha
1949:, Texas congressman.
1911:, diagnosed in 2015.
1682:, diagnosed in 2014.
1631:non-Hodgkin lymphoma
1484: more than 19.8
1301:Supportive treatment
1067:chemotherapy regimen
978:non-Hodgkin lymphoma
931:Reed-Sternberg cells
608:non-Hodgkin lymphoma
249:enlarged lymph nodes
247:. Often, nonpainful
229:Reed–Sternberg cells
152:stem-cell transplant
106:enlarged lymph nodes
7029:Helicobacter pylori
6856:Nodal marginal zone
6783:Hairy cell leukemia
6649:and related disease
5797:Nevyjasněná úmrtí V
1937:Los Angeles Dodgers
1861:Pittsburgh Penguins
1826:Harry Potter movies
1418: less than 1.8
762:computed tomography
625:Lymphocyte depleted
7573:Lymphoid leukemias
7493:Leukemoid reaction
7329:Angioimmunoblastic
6995:Burkitt's lymphoma
6564:External resources
6390:Jacobs CD (2010).
6267:The New York Times
6078:The New York Times
6049:on April 30, 2013.
6019:on 22 October 2015
5881:The New York Times
5474:James TG (2012) .
5161:Cancer Research UK
4973:. pp. 62–64.
4514:transplantation".
4341:10.2146/ajhp110608
4280:Annals of Oncology
4227:"Hodgkin lymphoma"
3913:Annals of Oncology
3680:"Hodgkin lymphoma"
3229:Annals of Oncology
3100:"Hodgkin lymphoma"
2933:(6499): eabb9601.
2764:"Hodgkin Lymphoma"
2729:2015-09-20 at the
2647:"Hodgkin Lymphoma"
2560:10.3322/caac.21219
2194:. August 3, 2016.
2130:. August 3, 2016.
2043:(9859): 2095–128.
1907:, Croatian soccer
1792:on 25 August 2023.
1758:Mist Edvardsdóttir
1676:Kansas City Chiefs
1563:
1488:
1288:growth retardation
927:
909:
687:
679:
434:Nephrotic syndrome
398:Hepatosplenomegaly
305:Signs and symptoms
264:Epstein–Barr virus
120:, family history,
118:Epstein–Barr virus
18:Hodgkin’s lymphoma
7581:
7580:
7506:
7505:
7446:
7445:
7380:
7379:
7308:
7307:
7224:Mycosis fungoides
7091:
7090:
6949:
6948:
6893:Nodular sclerosis
6808:follicular B cell
6609:
6608:
6405:978-0-8047-7448-2
6287:. 30 October 2021
6194:. ExpressNews.com
5795:Skálová, Johana.
5527:(Subscription or
5487:978-1-84511-258-5
5453:978-1-64095-416-8
5421:. 6 February 2024
5399:. 6 February 2024
5236:978-0-7817-6422-3
4980:978-0-7817-1502-7
4967:Hodgkin's Disease
4237:(10): 3439–3447.
4195:10.1002/ajh.23750
4139:(9844): 836–847.
4020:(11): 4285–4289.
3686:. 23 October 2017
3607:(23): 4065–4080.
3407:(11): 1574–1583.
3395:Ansell S (2015).
3283:10.1002/ijc.21716
3235:(Suppl 1): 11–8.
3027:978-92-832-4494-3
2989:10.1111/bjh.13842
2799:978-0-7817-6422-3
2790:Hodgkin's disease
2746:978-90-5702-215-9
2375:978-1-118-29300-3
1977:Brandon Tartikoff
1845:stand up comedian
1824:in the first two
1734:Arizona Cardinals
1646:radiation therapy
1585:, and one was of
1571:Marcello Malpighi
1505:nodular sclerosis
1360:White blood count
1292:alkylating agents
1278:, lymphomas, and
1236:
1235:
993:radiation therapy
883:nodular sclerosis
701:markers (such as
693:markers (such as
667:
666:
428:Pel–Ebstein fever
283:radiation therapy
202:
201:
148:radiation therapy
134:Lymph node biopsy
129:Diagnostic method
32:Medical condition
16:(Redirected from
7616:
7594:Hodgkin lymphoma
7343:Lennert lymphoma
7209:
7140:
7102:
6967:Primary effusion
6700:
6689:
6656:
6636:
6629:
6622:
6613:
6600:Hodgkin lymphoma
6457:
6449:at the American
6447:Hodgkin Lymphoma
6438:Hodgkin Lymphoma
6429:Hodgkin lymphoma
6417:
6377:
6376:
6374:
6373:
6358:
6352:
6351:
6349:
6347:
6332:
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6325:
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6322:
6303:
6297:
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6230:
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6103:
6096:
6090:
6089:
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6085:
6068:
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6050:
6045:. Archived from
6035:
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6028:
6026:
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6008:
6002:
6001:
5999:
5997:
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5976:
5975:
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5897:
5896:
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5892:
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5867:
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5863:
5854:. Archived from
5844:
5838:
5837:
5835:
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5793:
5787:
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5785:
5784:
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5618:Michael Cuccione
5615:
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5608:
5606:
5605:
5590:
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5581:
5580:
5571:. Archived from
5565:
5559:
5558:
5556:
5554:
5549:on March 3, 2014
5539:
5533:
5532:
5524:
5505:James T (2004).
5502:
5496:
5495:
5471:
5465:
5464:
5462:
5460:
5446:. Sound Wisdom.
5437:
5431:
5430:
5428:
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5406:
5404:
5393:
5387:
5386:
5384:
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5344:
5343:
5332:
5326:
5325:
5315:
5291:
5276:
5275:
5247:
5241:
5240:
5227:Hodgkin Lymphoma
5222:
5205:
5204:
5202:
5201:
5190:"Lymphoma | CDC"
5186:
5177:
5176:
5174:
5172:
5153:
5147:
5146:
5144:
5143:
5134:. Archived from
5124:
5118:
5117:
5107:
5075:
5069:
5068:
5058:
5026:
5015:
5014:
5012:
5010:
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4733:
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4683:
4682:
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4634:
4633:
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4591:
4585:
4584:
4574:
4557:(11): CD010983.
4542:
4536:
4535:
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4504:
4503:
4493:
4469:
4463:
4462:
4452:
4420:
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4411:
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4388:
4359:
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4320:
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4313:
4303:
4271:
4265:
4264:
4254:
4243:10.1172/jci61245
4222:
4216:
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4197:
4173:
4167:
4166:
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4118:
4117:
4089:
4083:
4082:
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4047:
4029:
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3970:
3964:
3963:
3961:
3960:
3945:
3939:
3938:
3928:
3904:
3898:
3897:
3879:
3870:(36): 9198–207.
3855:
3849:
3848:
3838:
3828:
3804:
3798:
3797:
3787:
3755:
3749:
3748:
3738:
3705:
3696:
3695:
3693:
3691:
3676:
3667:
3666:
3665:
3664:
3641:
3635:
3634:
3624:
3591:
3585:
3584:
3574:
3550:
3544:
3543:
3533:
3527:
3526:
3525:
3524:
3501:
3495:
3494:
3482:
3476:
3475:
3457:
3433:
3427:
3426:
3416:
3392:
3386:
3385:
3375:
3351:
3345:
3344:
3326:
3311:Modern Pathology
3302:
3296:
3295:
3285:
3261:
3255:
3254:
3244:
3220:
3214:
3213:
3211:
3209:
3204:on March 4, 2009
3200:. Archived from
3194:
3185:
3184:
3166:
3142:
3136:
3135:
3095:
3089:
3088:
3070:
3046:
3040:
3039:
3013:
3002:
3001:
2991:
2967:
2961:
2960:
2950:
2918:
2912:
2911:
2909:
2908:
2894:
2888:
2887:
2877:
2845:
2839:
2838:
2810:
2804:
2803:
2785:
2779:
2778:
2776:
2774:
2760:
2751:
2750:
2721:
2708:
2707:
2697:
2673:
2667:
2666:
2664:
2662:
2642:
2623:
2622:
2612:
2588:
2573:
2572:
2562:
2538:
2532:
2531:
2495:
2489:
2488:
2452:
2446:
2445:
2433:
2424:
2423:
2395:
2384:
2383:
2359:
2353:
2352:
2342:
2309:
2300:
2299:
2289:
2256:
2247:
2246:
2244:
2242:
2223:
2208:
2207:
2205:
2203:
2184:
2173:
2172:
2155:
2144:
2143:
2141:
2139:
2120:
2097:
2096:
2078:
2060:
2028:
2005:Richard Holliday
1941:San Diego Padres
1923:New York Yankees
1822:Albus Dumbledore
1740:Michael Cuccione
1612:Theodor Langhans
1483:
1477:
1471:
1465:
1459:
1453:
1447:
1441:
1435:
1429:
1423:
1417:
1411:
1404:multiple myeloma
1396:Age-standardized
1343:Lymphocyte count
1333:Stage IV disease
1195:Cyclophosphamide
1007:
862:
850:
838:
826:
512:
330:chest radiograph
221:white blood cell
205:Hodgkin lymphoma
55:
38:Hodgkin lymphoma
35:
21:
7624:
7623:
7619:
7618:
7617:
7615:
7614:
7613:
7584:
7583:
7582:
7577:
7541:
7502:
7464:
7452:
7442:
7410:
7389:
7376:
7353:
7314:
7304:
7253:
7198:
7146:
7144:
7119:
7114:
7108:
7087:
7039:
6945:
6922:
6910:
6866:
6804:germinal center
6788:
6757:
6719:
6695:
6693:
6673:
6668:
6662:
6650:
6640:
6610:
6605:
6604:
6559:
6558:
6522:: 9650/3-9667/3
6468:
6425:
6406:
6389:
6386:
6384:Further reading
6381:
6380:
6371:
6369:
6360:
6359:
6355:
6345:
6343:
6334:
6333:
6329:
6320:
6318:
6311:Chicago Tribune
6305:
6304:
6300:
6290:
6288:
6279:
6278:
6274:
6260:
6259:
6255:
6245:
6243:
6238:
6237:
6233:
6224:
6222:
6213:
6211:
6207:
6197:
6195:
6185:
6184:
6180:
6171:
6169:
6160:
6159:
6155:
6145:
6143:
6134:
6133:
6129:
6119:
6117:
6112:
6111:
6107:
6098:
6097:
6093:
6083:
6081:
6070:
6069:
6065:
6058:
6054:
6043:Daily Telegraph
6037:
6036:
6032:
6022:
6020:
6010:
6009:
6005:
5995:
5993:
5984:
5983:
5979:
5969:
5967:
5958:
5957:
5950:
5940:
5938:
5930:
5929:
5925:
5916:
5914:
5905:
5904:
5900:
5890:
5888:
5875:
5874:
5870:
5861:
5859:
5846:
5845:
5841:
5832:
5830:
5816:
5815:
5811:
5794:
5790:
5782:
5780:
5773:
5772:
5768:
5758:
5756:
5745:
5744:
5740:
5725:
5724:
5720:
5710:
5708:
5696:
5695:
5691:
5681:
5679:
5675:Dagblaðið Vísir
5667:
5666:
5662:
5652:
5650:
5646:
5645:
5641:
5628:
5627:
5623:
5616:
5612:
5603:
5601:
5592:
5591:
5587:
5578:
5576:
5567:
5566:
5562:
5552:
5550:
5541:
5540:
5536:
5526:
5504:
5503:
5499:
5488:
5473:
5472:
5468:
5458:
5456:
5454:
5439:
5438:
5434:
5424:
5422:
5417:
5416:
5412:
5402:
5400:
5395:
5394:
5390:
5380:
5378:
5373:
5372:
5368:
5355:
5354:
5350:
5341:
5339:
5334:
5333:
5329:
5293:
5292:
5279:
5249:
5248:
5244:
5237:
5224:
5223:
5208:
5199:
5197:
5188:
5187:
5180:
5170:
5168:
5155:
5154:
5150:
5141:
5139:
5126:
5125:
5121:
5090:(12): 3786–91.
5077:
5076:
5072:
5041:(1): e2014048.
5028:
5027:
5018:
5008:
5006:
4993:
4992:
4988:
4981:
4964:
4963:
4959:
4949:
4947:
4934:
4933:
4929:
4885:
4884:
4877:
4833:
4832:
4828:
4782:
4781:
4777:
4754:(21): 1506–14.
4741:
4740:
4736:
4705:(19): 1916–27.
4691:
4690:
4686:
4655:(1): CD009075.
4642:
4641:
4637:
4606:(1): CD009768.
4593:
4592:
4588:
4544:
4543:
4539:
4518:(5): CD004269.
4512:
4511:
4507:
4471:
4470:
4466:
4441:10.1038/nrd4003
4422:
4421:
4417:
4408:
4406:
4399:"RTanswers.com"
4397:
4396:
4392:
4361:
4360:
4356:
4322:
4321:
4317:
4273:
4272:
4268:
4224:
4223:
4219:
4175:
4174:
4170:
4126:
4125:
4121:
4091:
4090:
4086:
4059:Curr Opin Oncol
4056:
4055:
4051:
4007:
4006:
4002:
3972:
3971:
3967:
3958:
3956:
3947:
3946:
3942:
3906:
3905:
3901:
3857:
3856:
3852:
3806:
3805:
3801:
3770:(4): CD007110.
3757:
3756:
3752:
3721:(8): CD012643.
3707:
3706:
3699:
3689:
3687:
3678:
3677:
3670:
3662:
3660:
3643:
3642:
3638:
3593:
3592:
3588:
3552:
3551:
3547:
3535:
3534:
3530:
3522:
3520:
3503:
3502:
3498:
3484:
3483:
3479:
3435:
3434:
3430:
3394:
3393:
3389:
3353:
3352:
3348:
3304:
3303:
3299:
3263:
3262:
3258:
3222:
3221:
3217:
3207:
3205:
3196:
3195:
3188:
3144:
3143:
3139:
3097:
3096:
3092:
3061:(12): 4553–60.
3048:
3047:
3043:
3028:
3015:
3014:
3005:
2969:
2968:
2964:
2920:
2919:
2915:
2906:
2904:
2896:
2895:
2891:
2860:(18): 3756–62.
2847:
2846:
2842:
2812:
2811:
2807:
2800:
2787:
2786:
2782:
2772:
2770:
2762:
2761:
2754:
2747:
2734:
2731:Wayback Machine
2722:
2711:
2675:
2674:
2670:
2660:
2658:
2644:
2643:
2626:
2603:(11): 1574–83.
2590:
2589:
2576:
2540:
2539:
2535:
2500:Human Pathology
2497:
2496:
2492:
2454:
2453:
2449:
2435:
2434:
2427:
2397:
2396:
2387:
2376:
2361:
2360:
2356:
2311:
2310:
2303:
2258:
2257:
2250:
2240:
2238:
2225:
2224:
2211:
2201:
2199:
2186:
2185:
2176:
2169:
2168:978-928320429-9
2157:
2156:
2147:
2137:
2135:
2122:
2121:
2100:
2030:
2029:
2022:
2017:
1917:, MLB All-Star
1905:Nikola Pokrivač
1802:Michael C. Hall
1720:medical neglect
1690:AFC Bournemouth
1658:
1627:histopathologic
1587:Robert Carswell
1555:
1546:
1538:
1529:
1523:T cell counts.
1492:other lymphomas
1486:
1485:
1481:
1479:
1475:
1473:
1469:
1467:
1466: 14.4–16.2
1463:
1461:
1460: 12.6–14.4
1457:
1455:
1454: 10.8–12.6
1451:
1449:
1445:
1443:
1439:
1437:
1433:
1431:
1427:
1425:
1421:
1419:
1415:
1413:
1409:
1389:
1312:
1303:
1271:
1269:Adverse effects
1060:Currently, the
986:
898:
878:
873:
866:
863:
854:
851:
842:
839:
830:
827:
741:
722:
483:
474:
450:
326:supraclavicular
314:Lymphadenopathy
307:
211:) is a type of
33:
28:
23:
22:
15:
12:
11:
5:
7622:
7620:
7612:
7611:
7606:
7601:
7596:
7586:
7585:
7579:
7578:
7576:
7575:
7570:
7565:
7563:Leukemia cutis
7560:
7555:
7549:
7547:
7543:
7542:
7540:
7539:
7534:
7533:
7532:
7527:
7516:
7514:
7508:
7507:
7504:
7503:
7501:
7500:
7495:
7490:
7484:
7474:
7472:
7466:
7465:
7463:
7462:
7456:
7454:
7448:
7447:
7444:
7443:
7441:
7440:
7435:
7418:
7416:
7412:
7411:
7409:
7408:
7403:
7397:
7395:
7382:
7381:
7378:
7377:
7375:
7374:
7361:
7359:
7355:
7354:
7352:
7351:
7346:
7336:
7331:
7326:
7320:
7318:
7310:
7309:
7306:
7305:
7303:
7302:
7297:
7292:
7282:
7281:
7276:
7271:
7261:
7259:
7255:
7254:
7252:
7251:
7243:Sézary disease
7237:
7236:
7231:
7226:
7217:
7215:
7206:
7200:
7199:
7197:
7196:
7190:
7178:
7177:
7174:Prolymphocytic
7164:
7150:
7148:
7137:
7136:
7135:
7129:
7099:
7093:
7092:
7089:
7088:
7086:
7085:
7080:
7075:
7070:
7065:
7060:
7055:
7049:
7047:
7041:
7040:
7038:
7037:
7025:
7013:
7012:
7011:
6999:
6998:
6997:
6992:
6987:
6982:
6970:
6957:
6955:
6951:
6950:
6947:
6946:
6944:
6943:
6934:
6932:
6912:
6911:
6909:
6908:
6896:
6885:
6883:
6868:
6867:
6865:
6864:
6858:
6853:
6848:
6832:
6831:
6825:
6820:
6815:
6799:
6797:
6790:
6789:
6787:
6786:
6774:
6772:Prolymphocytic
6768:
6766:
6759:
6758:
6756:
6755:
6743:
6730:
6728:
6721:
6720:
6718:
6708:
6706:
6697:
6686:
6685:
6684:
6652:
6651:
6641:
6639:
6638:
6631:
6624:
6616:
6607:
6606:
6603:
6602:
6591:
6580:
6568:
6567:
6565:
6561:
6560:
6557:
6556:
6545:
6534:
6523:
6515:
6500:
6485:
6469:
6464:
6463:
6461:
6460:Classification
6454:
6453:
6444:
6435:
6424:
6423:External links
6421:
6420:
6419:
6404:
6385:
6382:
6379:
6378:
6353:
6341:Post Wrestling
6327:
6298:
6272:
6253:
6231:
6217:. abc.go.com.
6205:
6178:
6153:
6127:
6105:
6091:
6063:
6060:Mamta Mohandas
6052:
6030:
6003:
5977:
5948:
5923:
5898:
5868:
5839:
5809:
5788:
5766:
5738:
5718:
5707:(in Icelandic)
5689:
5660:
5639:
5632:. 2014-07-04.
5621:
5610:
5585:
5560:
5534:
5497:
5486:
5466:
5452:
5432:
5410:
5388:
5366:
5348:
5327:
5277:
5242:
5235:
5206:
5178:
5148:
5119:
5070:
5016:
4986:
4979:
4957:
4927:
4875:
4846:(6): 1408–13.
4826:
4795:(23): 2780–5.
4775:
4734:
4684:
4635:
4586:
4537:
4505:
4464:
4435:(7): 526–542.
4415:
4390:
4354:
4335:(7): 589–597.
4315:
4266:
4217:
4188:(7): 771–779.
4168:
4119:
4084:
4065:(5): 308–316.
4049:
4000:
3965:
3940:
3919:(3): 574–581.
3899:
3850:
3799:
3750:
3697:
3668:
3636:
3601:Blood Advances
3586:
3545:
3528:
3496:
3477:
3448:(10): 1594–7.
3428:
3387:
3366:(8): 3339–47.
3346:
3317:(12): 1542–9.
3297:
3276:(8): 1853–61.
3256:
3215:
3186:
3157:(3): 267–281.
3137:
3110:(2): 216–237.
3090:
3041:
3026:
3003:
2962:
2913:
2902:www.cancer.org
2889:
2840:
2805:
2798:
2780:
2752:
2745:
2709:
2668:
2624:
2574:
2533:
2490:
2463:(2): 102–114.
2447:
2438:Med Chir Trans
2425:
2406:(7): 653–662.
2385:
2374:
2354:
2301:
2248:
2233:. April 2016.
2209:
2174:
2167:
2145:
2098:
2019:
2018:
2016:
2013:
2012:
2011:
2008:
2002:
1990:
1980:
1974:
1968:
1950:
1944:
1930:
1927:Boston Red Sox
1912:
1902:
1892:
1886:
1883:Mamta Mohandas
1880:
1874:
1864:
1854:
1838:
1832:
1829:
1818:Richard Harris
1815:
1799:
1796:Jiří Grossmann
1793:
1771:
1765:
1755:
1749:
1746:Victoria Duval
1743:
1737:
1723:
1713:
1703:
1693:
1683:
1665:
1657:
1654:
1616:Carl Sternberg
1583:Thomas Addison
1579:Richard Bright
1575:Guy's Hospital
1567:Thomas Hodgkin
1554:
1551:
1545:
1542:
1537:
1534:
1528:
1525:
1480:
1474:
1468:
1462:
1456:
1450:
1444:
1438:
1432:
1426:
1420:
1414:
1408:
1407:
1388:
1385:
1364:
1363:
1357:
1351:
1346:
1340:
1339:< 10.5 g/dl
1334:
1331:
1330:Age ≥ 45 years
1311:
1308:
1302:
1299:
1270:
1267:
1234:
1233:
1228:
1223:
1221:
1218:
1217:
1212:
1207:
1205:
1202:
1201:
1192:
1187:
1182:
1176:
1175:
1170:
1161:
1156:
1150:
1149:
1144:
1139:
1134:
1128:
1127:
1122:
1117:
1112:
1106:
1105:
1094:
1086:
1058:
1029:
1028:
1023:
1018:
1013:
985:
982:
974:
973:
970:
967:
964:
961:
897:
894:
877:
874:
872:
869:
868:
867:
864:
857:
855:
852:
845:
843:
840:
833:
831:
828:
821:
814:
813:
810:
803:
796:
778:lymphangiogram
740:
737:
721:
718:
714:interleukin-21
665:
664:
659:
654:
652:
648:
647:
642:
637:
626:
622:
621:
616:
611:
604:
597:
596:
590:
585:
577:
573:
572:
567:
562:
536:
530:
529:
524:
519:
516:
482:
479:
473:
470:
449:
446:
445:
444:
441:
431:
424:
418:
401:
395:
385:
375:
374:
373:
366:
360:
353:
346:
341:
333:
306:
303:
233:Thomas Hodgkin
200:
199:
197:Thomas Hodgkin
194:
188:
187:
184:
180:
179:
176:
172:
171:
165:
159:
158:
141:
137:
136:
131:
125:
124:
115:
109:
108:
91:
85:
84:
75:
69:
68:
57:
56:
48:
47:
44:
40:
39:
31:
26:
24:
14:
13:
10:
9:
6:
4:
3:
2:
7621:
7610:
7607:
7605:
7602:
7600:
7597:
7595:
7592:
7591:
7589:
7574:
7571:
7569:
7566:
7564:
7561:
7559:
7556:
7554:
7551:
7550:
7548:
7544:
7538:
7535:
7531:
7528:
7526:
7523:
7522:
7521:
7518:
7517:
7515:
7513:
7509:
7499:
7496:
7494:
7491:
7488:
7485:
7483:
7479:
7476:
7475:
7473:
7471:
7470:Lymphocytosis
7467:
7461:
7458:
7457:
7455:
7449:
7439:
7436:
7433:
7429:
7425:
7424:
7420:
7419:
7417:
7413:
7407:
7404:
7402:
7399:
7398:
7396:
7393:
7387:
7383:
7372:
7368:
7367:
7363:
7362:
7360:
7356:
7350:
7347:
7344:
7340:
7337:
7335:
7332:
7330:
7327:
7325:
7324:Hepatosplenic
7322:
7321:
7319:
7317:
7311:
7301:
7298:
7296:
7293:
7291:
7287:
7284:
7283:
7280:
7277:
7275:
7272:
7270:
7266:
7263:
7262:
7260:
7256:
7250:
7247:
7246:
7245:
7244:
7241:
7235:
7232:
7230:
7227:
7225:
7222:
7219:
7218:
7216:
7214:
7210:
7207:
7205:
7201:
7194:
7191:
7189:
7185:
7184:
7180:
7179:
7175:
7171:
7170:
7169:prolymphocyte
7166:
7165:
7162:
7158:
7154:
7151:
7149:
7141:
7138:
7133:
7130:
7128:
7125:
7124:
7123:
7117:
7112:
7107:
7103:
7100:
7098:
7094:
7084:
7081:
7079:
7078:Plasmacytosis
7076:
7074:
7071:
7069:
7066:
7064:
7061:
7059:
7056:
7054:
7051:
7050:
7048:
7046:
7042:
7035:
7034:MALT lymphoma
7031:
7030:
7026:
7023:
7019:
7018:
7014:
7010:
7007:
7006:
7005:
7004:
7000:
6996:
6993:
6991:
6988:
6986:
6983:
6981:
6978:
6977:
6976:
6975:
6971:
6968:
6964:
6963:
6959:
6958:
6956:
6952:
6942:
6941:
6936:
6935:
6933:
6930:
6926:
6921:
6917:
6913:
6906:
6902:
6901:
6897:
6894:
6890:
6887:
6886:
6884:
6881:
6877:
6873:
6869:
6862:
6859:
6857:
6854:
6852:
6849:
6847:
6843:
6842:
6838:
6837:marginal zone
6834:
6833:
6829:
6826:
6824:
6821:
6819:
6816:
6814:
6810:
6809:
6805:
6801:
6800:
6798:
6795:
6791:
6784:
6780:
6779:
6775:
6773:
6770:
6769:
6767:
6764:
6760:
6753:
6749:
6748:
6744:
6741:
6737:
6736:
6732:
6731:
6729:
6726:
6722:
6716:
6712:
6709:
6707:
6705:
6701:
6698:
6690:
6687:
6682:
6679:
6678:
6677:
6671:
6666:
6661:
6657:
6653:
6648:
6644:
6637:
6632:
6630:
6625:
6623:
6618:
6617:
6614:
6601:
6597:
6596:
6592:
6590:
6586:
6585:
6581:
6579:
6575:
6574:
6570:
6569:
6566:
6562:
6555:
6551:
6550:
6546:
6544:
6540:
6539:
6535:
6533:
6529:
6528:
6524:
6521:
6520:
6516:
6514:
6510:
6509:
6505:
6501:
6499:
6495:
6494:
6490:
6486:
6484:
6480:
6479:
6475:
6471:
6470:
6467:
6462:
6458:
6452:
6448:
6445:
6443:
6439:
6436:
6434:
6430:
6427:
6426:
6422:
6415:
6411:
6407:
6401:
6397:
6393:
6388:
6387:
6383:
6368:
6364:
6357:
6354:
6342:
6338:
6331:
6328:
6317:on 2016-03-17
6316:
6312:
6308:
6302:
6299:
6286:
6282:
6276:
6273:
6268:
6264:
6257:
6254:
6241:
6235:
6232:
6220:
6216:
6209:
6206:
6198:September 18,
6193:
6189:
6182:
6179:
6167:
6163:
6157:
6154:
6141:
6137:
6131:
6128:
6115:
6109:
6106:
6101:
6095:
6092:
6080:
6079:
6074:
6067:
6064:
6061:
6056:
6053:
6048:
6044:
6040:
6034:
6031:
6018:
6014:
6007:
6004:
5991:
5987:
5981:
5978:
5966:
5962:
5955:
5953:
5949:
5937:
5933:
5927:
5924:
5913:on 2015-12-22
5912:
5908:
5902:
5899:
5886:
5882:
5878:
5872:
5869:
5858:on 2015-02-04
5857:
5853:
5849:
5843:
5840:
5828:
5824:
5820:
5813:
5810:
5806:
5805:80-902731-7-3
5802:
5798:
5792:
5789:
5779:
5778:
5770:
5767:
5755:
5754:
5749:
5742:
5739:
5735:. 2003-07-14.
5734:
5733:
5728:
5722:
5719:
5706:
5705:
5700:
5693:
5690:
5677:
5676:
5671:
5664:
5661:
5649:
5643:
5640:
5635:
5631:
5625:
5622:
5619:
5614:
5611:
5600:on 2016-08-18
5599:
5595:
5589:
5586:
5575:on 2016-09-12
5574:
5570:
5564:
5561:
5548:
5544:
5538:
5535:
5530:
5522:
5518:
5514:
5513:
5508:
5501:
5498:
5493:
5489:
5483:
5479:
5478:
5470:
5467:
5455:
5449:
5445:
5444:
5436:
5433:
5420:
5414:
5411:
5398:
5392:
5389:
5376:
5370:
5367:
5362:
5358:
5352:
5349:
5337:
5331:
5328:
5323:
5319:
5314:
5309:
5305:
5301:
5297:
5290:
5288:
5286:
5284:
5282:
5278:
5273:
5269:
5265:
5261:
5258:(6): 386–93.
5257:
5253:
5246:
5243:
5238:
5232:
5228:
5221:
5219:
5217:
5215:
5213:
5211:
5207:
5195:
5191:
5185:
5183:
5179:
5166:
5162:
5158:
5152:
5149:
5138:on 2018-01-25
5137:
5133:
5132:www.cancer.ca
5129:
5123:
5120:
5115:
5111:
5106:
5101:
5097:
5093:
5089:
5085:
5081:
5074:
5071:
5066:
5062:
5057:
5052:
5048:
5044:
5040:
5036:
5032:
5025:
5023:
5021:
5017:
5004:
5000:
4996:
4990:
4987:
4982:
4976:
4972:
4968:
4961:
4958:
4945:
4941:
4937:
4931:
4928:
4923:
4919:
4915:
4911:
4906:
4901:
4898:(5): 683–90.
4897:
4893:
4889:
4882:
4880:
4876:
4871:
4867:
4862:
4857:
4853:
4849:
4845:
4841:
4837:
4830:
4827:
4822:
4818:
4813:
4808:
4803:
4798:
4794:
4790:
4786:
4779:
4776:
4771:
4767:
4762:
4757:
4753:
4749:
4745:
4738:
4735:
4730:
4726:
4722:
4718:
4713:
4708:
4704:
4700:
4696:
4688:
4685:
4680:
4676:
4671:
4666:
4662:
4658:
4654:
4650:
4646:
4639:
4636:
4631:
4627:
4622:
4617:
4613:
4609:
4605:
4601:
4597:
4590:
4587:
4582:
4578:
4573:
4568:
4564:
4560:
4556:
4552:
4548:
4541:
4538:
4533:
4529:
4525:
4521:
4517:
4509:
4506:
4501:
4497:
4492:
4487:
4483:
4479:
4475:
4468:
4465:
4460:
4456:
4451:
4446:
4442:
4438:
4434:
4430:
4426:
4419:
4416:
4405:on 2012-09-09
4404:
4400:
4394:
4391:
4386:
4382:
4378:
4374:
4371:(4): 854–62.
4370:
4366:
4358:
4355:
4350:
4346:
4342:
4338:
4334:
4330:
4326:
4319:
4316:
4311:
4307:
4302:
4297:
4293:
4289:
4285:
4281:
4277:
4270:
4267:
4262:
4258:
4253:
4248:
4244:
4240:
4236:
4232:
4228:
4221:
4218:
4213:
4209:
4205:
4201:
4196:
4191:
4187:
4183:
4179:
4172:
4169:
4164:
4160:
4156:
4152:
4147:
4142:
4138:
4134:
4130:
4123:
4120:
4115:
4111:
4107:
4103:
4099:
4095:
4088:
4085:
4080:
4076:
4072:
4068:
4064:
4060:
4053:
4050:
4045:
4041:
4037:
4033:
4028:
4023:
4019:
4015:
4011:
4004:
4001:
3996:
3992:
3988:
3984:
3981:(5): 385–90.
3980:
3976:
3969:
3966:
3955:on 2011-08-17
3954:
3950:
3944:
3941:
3936:
3932:
3927:
3922:
3918:
3914:
3910:
3903:
3900:
3895:
3891:
3887:
3883:
3878:
3873:
3869:
3865:
3861:
3854:
3851:
3846:
3842:
3837:
3832:
3827:
3822:
3818:
3814:
3810:
3803:
3800:
3795:
3791:
3786:
3781:
3777:
3773:
3769:
3765:
3761:
3754:
3751:
3746:
3742:
3737:
3732:
3728:
3724:
3720:
3716:
3712:
3704:
3702:
3698:
3685:
3681:
3675:
3673:
3669:
3659:
3655:
3651:
3647:
3640:
3637:
3632:
3628:
3623:
3618:
3614:
3610:
3606:
3602:
3598:
3590:
3587:
3582:
3578:
3573:
3568:
3565:(12): 591–7.
3564:
3560:
3556:
3549:
3546:
3541:
3540:
3532:
3529:
3519:
3515:
3511:
3507:
3500:
3497:
3492:
3488:
3481:
3478:
3473:
3469:
3465:
3461:
3456:
3451:
3447:
3443:
3439:
3432:
3429:
3424:
3420:
3415:
3410:
3406:
3402:
3398:
3391:
3388:
3383:
3379:
3374:
3369:
3365:
3361:
3357:
3350:
3347:
3342:
3338:
3334:
3330:
3325:
3320:
3316:
3312:
3308:
3301:
3298:
3293:
3289:
3284:
3279:
3275:
3271:
3267:
3260:
3257:
3252:
3248:
3243:
3238:
3234:
3230:
3226:
3219:
3216:
3203:
3199:
3193:
3191:
3187:
3182:
3178:
3174:
3170:
3165:
3160:
3156:
3152:
3148:
3141:
3138:
3133:
3129:
3125:
3121:
3117:
3113:
3109:
3105:
3101:
3094:
3091:
3086:
3082:
3078:
3074:
3069:
3064:
3060:
3056:
3052:
3045:
3042:
3037:
3033:
3029:
3023:
3019:
3012:
3010:
3008:
3004:
2999:
2995:
2990:
2985:
2981:
2977:
2973:
2966:
2963:
2958:
2954:
2949:
2944:
2940:
2936:
2932:
2928:
2924:
2917:
2914:
2903:
2899:
2893:
2890:
2885:
2881:
2876:
2871:
2867:
2863:
2859:
2855:
2851:
2844:
2841:
2836:
2832:
2828:
2824:
2820:
2816:
2809:
2806:
2801:
2795:
2791:
2784:
2781:
2769:
2765:
2759:
2757:
2753:
2748:
2742:
2738:
2732:
2728:
2725:
2720:
2718:
2716:
2714:
2710:
2705:
2701:
2696:
2691:
2687:
2683:
2679:
2672:
2669:
2656:
2652:
2648:
2641:
2639:
2637:
2635:
2633:
2631:
2629:
2625:
2620:
2616:
2611:
2606:
2602:
2598:
2594:
2587:
2585:
2583:
2581:
2579:
2575:
2570:
2566:
2561:
2556:
2553:(2): 83–103.
2552:
2548:
2544:
2537:
2534:
2529:
2525:
2521:
2517:
2513:
2509:
2505:
2501:
2494:
2491:
2486:
2482:
2478:
2474:
2470:
2466:
2462:
2458:
2451:
2448:
2443:
2439:
2432:
2430:
2426:
2421:
2417:
2413:
2409:
2405:
2401:
2394:
2392:
2390:
2386:
2381:
2377:
2371:
2367:
2366:
2358:
2355:
2350:
2346:
2341:
2336:
2332:
2328:
2324:
2320:
2316:
2308:
2306:
2302:
2297:
2293:
2288:
2283:
2279:
2275:
2271:
2267:
2263:
2255:
2253:
2249:
2236:
2232:
2228:
2222:
2220:
2218:
2216:
2214:
2210:
2197:
2193:
2189:
2183:
2181:
2179:
2175:
2170:
2164:
2160:
2154:
2152:
2150:
2146:
2133:
2129:
2125:
2119:
2117:
2115:
2113:
2111:
2109:
2107:
2105:
2103:
2099:
2094:
2090:
2086:
2082:
2077:
2072:
2068:
2064:
2059:
2054:
2050:
2046:
2042:
2038:
2034:
2027:
2025:
2021:
2014:
2009:
2006:
2003:
2000:
1999:
1994:
1991:
1988:
1984:
1981:
1978:
1975:
1972:
1971:Arlen Specter
1969:
1966:
1962:
1958:
1954:
1953:Flip Saunders
1951:
1948:
1945:
1942:
1938:
1934:
1931:
1928:
1924:
1920:
1919:first baseman
1916:
1915:Anthony Rizzo
1913:
1910:
1906:
1903:
1900:
1896:
1895:Laura Packard
1893:
1890:
1889:Nanni Moretti
1887:
1884:
1881:
1878:
1877:Jack Lisowski
1875:
1872:
1868:
1865:
1862:
1858:
1857:Mario Lemieux
1855:
1852:
1851:
1846:
1842:
1839:
1836:
1833:
1830:
1827:
1823:
1819:
1816:
1813:
1812:
1807:
1806:Dexter Morgan
1803:
1800:
1797:
1794:
1791:
1787:
1783:
1779:
1775:
1772:
1769:
1768:Delta Goodrem
1766:
1763:
1759:
1756:
1753:
1750:
1747:
1744:
1741:
1738:
1735:
1731:
1727:
1724:
1721:
1717:
1714:
1711:
1707:
1706:Howard Carter
1704:
1701:
1697:
1696:Dale Carnegie
1694:
1691:
1687:
1684:
1681:
1677:
1673:
1672:strong safety
1669:
1666:
1663:
1660:
1659:
1656:Notable cases
1655:
1653:
1651:
1647:
1642:
1640:
1636:
1632:
1628:
1623:
1621:
1617:
1613:
1609:
1606:
1601:
1599:
1595:
1590:
1588:
1584:
1581:, one was of
1580:
1576:
1572:
1568:
1559:
1552:
1550:
1544:United States
1543:
1541:
1535:
1533:
1526:
1524:
1522:
1518:
1513:
1509:
1506:
1501:
1497:
1493:
1478: 18–19.8
1472: 16.2–18
1436: 5.4–7.2
1430: 3.6–5.4
1424: 1.8–3.6
1412: no data
1405:
1401:
1397:
1393:
1386:
1384:
1380:
1376:
1374:
1370:
1361:
1358:
1356:< 4.0 g/dl
1355:
1352:
1350:
1347:
1344:
1341:
1338:
1335:
1332:
1329:
1328:
1327:
1324:
1320:
1318:
1309:
1307:
1300:
1298:
1295:
1293:
1289:
1284:
1281:
1277:
1268:
1266:
1264:
1258:
1256:
1251:
1247:
1243:
1241:
1232:
1229:
1227:
1224:
1222:
1220:
1219:
1216:
1213:
1211:
1208:
1206:
1204:
1203:
1200:
1196:
1193:
1191:
1188:
1186:
1183:
1181:
1178:
1177:
1174:
1171:
1169:
1165:
1162:
1160:
1157:
1155:
1152:
1151:
1148:
1145:
1143:
1140:
1138:
1135:
1133:
1130:
1129:
1126:
1123:
1121:
1118:
1116:
1113:
1111:
1108:
1107:
1103:
1098:
1095:
1091:
1087:
1084:
1080:
1076:
1072:
1068:
1065:
1064:
1059:
1057:
1053:
1049:
1045:
1041:
1037:
1036:
1031:
1030:
1027:
1024:
1022:
1019:
1017:
1014:
1012:
1009:
1008:
1005:
1003:
999:
994:
989:
983:
981:
979:
971:
968:
965:
962:
959:
958:
957:
954:
952:
946:
944:
940:
936:
932:
925:
924:H&E stain
921:
917:
913:
906:
902:
895:
893:
892:may be seen.
891:
886:
884:
875:
870:
861:
856:
849:
844:
837:
832:
825:
820:
818:
811:
808:
804:
801:
797:
794:
793:
792:
790:
785:
783:
779:
775:
771:
767:
763:
760:radiographs,
759:
755:
751:
750:
744:
738:
736:
734:
730:
726:
719:
717:
715:
710:
708:
704:
700:
696:
692:
683:
676:
671:
663:
660:
658:
655:
653:
650:
649:
646:
643:
641:
638:
635:
631:
627:
624:
623:
620:
617:
615:
612:
609:
605:
602:
599:
598:
594:
591:
589:
586:
583:
578:
575:
574:
571:
568:
566:
563:
560:
556:
552:
548:
544:
541:
537:
535:
532:
531:
528:
525:
523:
520:
517:
514:
513:
510:
507:
504:
500:
496:
492:
488:
480:
478:
471:
469:
467:
463:
459:
455:
447:
442:
439:
435:
432:
429:
425:
422:
419:
415:
414:pathognomonic
411:
407:
402:
399:
396:
393:
389:
386:
383:
379:
376:
371:
367:
364:
361:
358:
354:
351:
347:
345:
342:
340:
337:
336:
334:
331:
327:
323:
319:
315:
312:
311:
310:
304:
302:
298:
296:
295:heart disease
292:
288:
284:
280:
275:
273:
269:
265:
261:
256:
254:
250:
246:
242:
238:
234:
230:
226:
222:
218:
214:
210:
206:
198:
195:
193:
189:
186:23,900 (2015)
185:
181:
177:
173:
169:
166:
164:
160:
157:
156:immunotherapy
153:
149:
145:
142:
138:
135:
132:
130:
126:
123:
119:
116:
114:
110:
107:
104:, nonpainful
103:
99:
95:
92:
90:
86:
83:
79:
76:
74:
70:
66:
62:
58:
54:
49:
45:
41:
36:
30:
19:
7604:Rare cancers
7421:
7364:
7358:By infection
7239:
7238:
7220:
7181:
7167:
7145:development/
7073:Plasmacytoma
7027:
7015:
7001:
6989:
6972:
6960:
6954:By infection
6937:
6898:
6888:
6835:
6802:
6776:
6745:
6735:naive B cell
6733:
6694:development/
6593:
6582:
6571:
6547:
6536:
6525:
6517:
6502:
6487:
6472:
6391:
6370:. Retrieved
6366:
6356:
6344:. Retrieved
6340:
6330:
6319:. Retrieved
6315:the original
6310:
6301:
6289:. Retrieved
6284:
6275:
6266:
6256:
6244:. Retrieved
6234:
6223:. Retrieved
6208:
6196:. Retrieved
6191:
6181:
6170:. Retrieved
6168:. 2010-05-03
6165:
6156:
6144:. Retrieved
6130:
6120:10 September
6118:. Retrieved
6108:
6094:
6082:. Retrieved
6076:
6066:
6055:
6047:the original
6042:
6033:
6021:. Retrieved
6017:the original
6006:
5994:. Retrieved
5980:
5968:. Retrieved
5964:
5939:. Retrieved
5935:
5926:
5915:. Retrieved
5911:the original
5901:
5889:. Retrieved
5880:
5871:
5860:. Retrieved
5856:the original
5851:
5842:
5831:. Retrieved
5822:
5812:
5796:
5791:
5781:, retrieved
5776:
5769:
5757:. Retrieved
5751:
5741:
5730:
5721:
5709:. Retrieved
5702:
5692:
5680:. Retrieved
5673:
5663:
5651:. Retrieved
5642:
5624:
5613:
5602:. Retrieved
5598:the original
5588:
5577:. Retrieved
5573:the original
5563:
5551:. Retrieved
5547:the original
5537:
5510:
5500:
5476:
5469:
5457:. Retrieved
5442:
5435:
5423:. Retrieved
5413:
5401:. Retrieved
5391:
5379:. Retrieved
5369:
5351:
5340:. Retrieved
5330:
5306:(8): 815–7.
5303:
5299:
5255:
5251:
5245:
5226:
5198:. Retrieved
5196:. 2019-01-16
5193:
5169:. Retrieved
5160:
5151:
5140:. Retrieved
5136:the original
5131:
5122:
5087:
5083:
5073:
5038:
5034:
5007:. Retrieved
4998:
4989:
4966:
4960:
4948:. Retrieved
4939:
4930:
4895:
4891:
4843:
4839:
4829:
4792:
4788:
4778:
4751:
4747:
4737:
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4698:
4687:
4652:
4648:
4638:
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4599:
4589:
4554:
4550:
4540:
4515:
4508:
4484:(1): 12–28.
4481:
4477:
4467:
4432:
4428:
4418:
4407:. Retrieved
4403:the original
4393:
4368:
4364:
4357:
4332:
4328:
4318:
4301:2318/1612165
4283:
4279:
4269:
4234:
4230:
4220:
4185:
4181:
4171:
4136:
4132:
4122:
4101:
4097:
4087:
4062:
4058:
4052:
4017:
4013:
4003:
3978:
3974:
3968:
3957:. Retrieved
3953:the original
3943:
3916:
3912:
3902:
3867:
3863:
3853:
3819:(2): 47–51.
3816:
3812:
3802:
3767:
3763:
3753:
3718:
3714:
3688:. Retrieved
3683:
3661:, retrieved
3649:
3639:
3604:
3600:
3589:
3562:
3558:
3548:
3538:
3531:
3521:, retrieved
3509:
3499:
3490:
3480:
3445:
3441:
3431:
3404:
3400:
3390:
3363:
3359:
3349:
3314:
3310:
3300:
3273:
3269:
3259:
3232:
3228:
3218:
3206:. Retrieved
3202:the original
3154:
3150:
3140:
3107:
3103:
3093:
3058:
3054:
3044:
3017:
2982:(1): 32–43.
2979:
2975:
2965:
2930:
2926:
2916:
2905:. Retrieved
2901:
2892:
2857:
2853:
2843:
2818:
2814:
2808:
2789:
2783:
2771:. Retrieved
2767:
2736:
2688:(6): 874–5.
2685:
2681:
2671:
2659:. Retrieved
2650:
2600:
2596:
2550:
2546:
2536:
2503:
2499:
2493:
2460:
2456:
2450:
2441:
2437:
2403:
2399:
2364:
2357:
2322:
2318:
2269:
2265:
2239:. Retrieved
2230:
2200:. Retrieved
2191:
2158:
2136:. Retrieved
2127:
2040:
2036:
1997:
1933:Dave Roberts
1867:Dinu Lipatti
1848:
1809:
1778:Vlogbrothers
1752:Gerald Finzi
1730:running back
1726:James Conner
1686:David Brooks
1643:
1635:tuberculosis
1624:
1620:Dorothy Reed
1610:
1605:Samuel Wilks
1602:
1597:
1591:
1564:
1547:
1539:
1530:
1514:
1510:
1490:Unlike some
1489:
1448: 9–10.8
1387:Epidemiology
1381:
1377:
1365:
1325:
1321:
1313:
1304:
1296:
1285:
1280:solid tumors
1272:
1259:
1252:
1248:
1244:
1237:
1199:Procarbazine
1190:Chlormethine
1180:Procarbazine
1110:Chlormethine
1061:
1055:
1052:Procarbazine
1033:
990:
987:
975:
955:
947:
928:
887:
879:
815:
786:
780:or surgical
774:gallium scan
747:
745:
742:
723:
711:
688:
558:
555:plasma cells
542:
501:seen in the
484:
475:
466:gallium scan
451:
388:Hepatomegaly
378:Splenomegaly
348:Unexplained
344:Night sweats
308:
299:
279:chemotherapy
276:
257:
241:night sweats
208:
204:
203:
144:Chemotherapy
113:Risk factors
98:night sweats
29:
7240:aggressive:
7213:MF+variants
6752:Mantle cell
6747:mantle zone
6573:MedlinePlus
6084:6 September
5653:27 November
5194:www.cdc.gov
4286:: iii70–5.
3493:. NBK65726.
3208:February 1,
2821:(1): 66–7.
1843:, American
1835:Tessa James
1710:Tutankhamun
1442: 7.2–9
1398:death from
1373:mediastinum
1362:≥ 15,000/μL
1185:Dacarbazine
1173:Vincristine
1168:Vincristine
1164:Vinblastine
1159:Vinblastine
1125:Doxorubicin
1120:Doxorubicin
1115:Doxorubicin
1083:dacarbazine
1079:vinblastine
673:Lymph node
651:Unspecified
551:eosinophils
547:lymphocytes
518:Description
458:Blood tests
406:sensitivity
365:(lassitude)
350:weight loss
318:lymph nodes
245:weight loss
225:lymphocytes
192:Named after
102:weight loss
65:Field stain
43:Other names
7588:Categories
7316:peripheral
6813:Follicular
6643:Leukaemias
6595:Patient UK
6538:DiseasesDB
6372:2024-01-18
6321:2016-03-26
6291:30 October
6225:2015-10-25
6172:2020-10-28
5917:2015-12-16
5862:2015-03-04
5833:2015-03-04
5783:2023-08-26
5604:2016-07-22
5579:2016-09-29
5531:required.)
5459:8 February
5425:8 February
5403:6 February
5381:13 October
5342:2017-12-23
5200:2019-11-25
5171:27 October
5142:2018-02-08
4409:2012-08-26
4133:The Lancet
3959:2012-08-26
3663:2022-11-09
3650:StatPearls
3523:2022-11-09
3510:StatPearls
3036:1011064243
2907:2022-11-09
2015:References
1993:Ethan Zohn
1957:head coach
1909:midfielder
1774:Hank Green
1670:, All-Pro
1668:Eric Berry
1662:Paul Allen
1337:Hemoglobin
1231:Prednisone
1226:Prednisone
1154:Prednisone
1090:Stanford V
1088:The newer
1071:Adriamycin
1048:Prednisone
1021:Stanford V
984:Management
956:Variants:
916:Micrograph
905:Micrograph
896:Microscopy
876:Macroscopy
782:laparotomy
601:Lymphocyte
503:lymph node
499:infiltrate
495:morphology
491:pathologic
370:B symptoms
355:Low-grade
339:Itchy skin
78:Hematology
61:Micrograph
7451:Lymphoid+
7221:indolent:
7204:Cutaneous
7045:Cutaneous
6823:GCB DLBCL
6818:Burkitt's
6647:lymphomas
6584:eMedicine
6549:SNOMED CT
6414:648759629
6246:31 August
6146:30 August
6023:30 August
5777:Remission
5732:Billboard
5009:18 August
2506:: 18–41.
2241:13 August
2202:13 August
2138:12 August
1871:cortisone
1841:Sean Kent
1790:remission
1786:Complexly
1603:In 1856,
1400:lymphomas
1310:Prognosis
1276:leukemias
1240:rituximab
1215:Etoposide
1210:Etoposide
1147:Bleomycin
1142:Bleomycin
1137:Bleomycin
1075:bleomycin
1040:Mustargen
951:chromatin
871:Pathology
800:diaphragm
754:histology
733:rituximab
559:sclerosis
448:Diagnosis
421:Back pain
215:in which
175:Frequency
163:Prognosis
140:Treatment
73:Specialty
7558:leukemia
7116:leukemia
7111:lymphoma
6670:leukemia
6665:lymphoma
6589:med/1022
6554:14537002
6219:Archived
6166:ESPN.com
6140:Archived
5996:11 April
5990:Archived
5891:June 18,
5885:Archived
5827:Archived
5711:23 April
5682:23 April
5634:Archived
5553:June 18,
5492:Archived
5361:Archived
5272:10594291
5165:Archived
5114:16917006
5065:25045456
5003:Archived
4944:Archived
4942:. 2009.
4914:23516309
4870:28083035
4821:27900988
4729:11153555
4721:17989384
4679:30702150
4630:30697701
4581:26576687
4532:22592695
4500:21896559
4459:23812271
4385:23790512
4349:23515511
4310:25185243
4261:23023715
4212:43857382
4204:24953862
4163:15815020
4155:22835602
4114:Archived
4110:17715698
4098:Oncology
4079:29994901
4044:16108474
4036:12586628
3995:21183282
3935:19759185
3894:24367707
3886:16172458
3845:23696962
3794:28447341
3745:31930780
3658:31194473
3631:31816062
3581:25418190
3518:32644754
3472:11505564
3464:19759113
3423:26541251
3382:18684866
3341:22493125
3333:16056244
3292:16385563
3251:12078890
3173:15086409
3132:27274760
3124:22867814
3077:15728122
2998:26538004
2957:32345712
2884:20200355
2727:Archived
2724:Page 242
2661:June 18,
2655:Archived
2619:26541251
2569:24488779
2528:47010934
2520:29885408
2485:46790198
2477:29316828
2444:: 69–97.
2420:20818856
2380:Archived
2349:27733281
2296:27733282
2235:Archived
2196:Archived
2132:Archived
2085:23245604
2076:10790329
2067:23245604
1998:Survivor
1987:FC Porto
1947:Chip Roy
1921:for the
1674:for the
1639:syphilis
1494:, whose
322:cervical
268:HIV/AIDS
213:lymphoma
170:88% (US)
122:HIV/AIDS
89:Symptoms
82:oncology
7546:General
7453:myeloid
7415:T or NK
7386:NK cell
6740:CLL/SLL
6532:D006689
5753:YouTube
5322:6381744
5313:2609834
5105:1895473
5056:4103499
4950:Nov 11,
4922:9959867
4861:5216291
4812:5146782
4770:9819449
4670:6354325
4621:6353308
4572:4717525
4450:3906736
4252:3534167
3836:3659263
3785:6478261
3736:6984446
3690:25 July
3622:6963251
3572:4308654
3181:2355660
3085:8192701
2948:7509949
2927:Science
2875:2890576
2835:7777006
2773:25 July
2704:6613116
2695:1010854
2340:5388903
2287:5055577
2093:1541253
1959:of the
1678:of the
1553:History
1500:bimodal
1354:Albumin
1132:Oncovin
1097:BEACOPP
1044:Oncovin
1026:BEACOPP
739:Staging
662:M9650/3
645:M9653/3
619:M9651/3
593:M9652/3
570:M9663/3
543:nodules
481:Classic
417:aching.
363:Fatigue
223:called
7390:(most
7366:HTLV-1
7258:Non-MF
7147:marker
7120:(most
7106:T cell
6778:CD11c+
6696:marker
6674:(most
6660:B cell
6578:000580
6433:Curlie
6412:
6402:
6363:"Home"
6346:23 May
5970:19 May
5941:19 May
5852:People
5823:People
5803:
5759:19 May
5525:
5484:
5450:
5320:
5310:
5270:
5233:
5112:
5102:
5063:
5053:
4977:
4920:
4912:
4868:
4858:
4819:
4809:
4768:
4727:
4719:
4677:
4667:
4628:
4618:
4579:
4569:
4530:
4498:
4457:
4447:
4383:
4347:
4308:
4259:
4249:
4210:
4202:
4161:
4153:
4108:
4077:
4042:
4034:
3993:
3933:
3892:
3884:
3843:
3833:
3792:
3782:
3743:
3733:
3656:
3629:
3619:
3579:
3569:
3516:
3470:
3462:
3421:
3380:
3339:
3331:
3290:
3249:
3179:
3171:
3130:
3122:
3083:
3075:
3034:
3024:
2996:
2955:
2945:
2882:
2872:
2833:
2796:
2743:
2702:
2692:
2617:
2567:
2526:
2518:
2483:
2475:
2418:
2372:
2347:
2337:
2319:Lancet
2294:
2284:
2266:Lancet
2165:
2091:
2083:
2073:
2065:
2037:Lancet
1811:Dexter
1782:VidCon
1637:, and
1527:Canada
1482:
1476:
1470:
1464:
1458:
1452:
1446:
1440:
1434:
1428:
1422:
1416:
1410:
1081:, and
807:spleen
768:(PET)/
749:staged
699:T-cell
691:B-cell
675:biopsy
522:ICD-10
506:biopsy
454:biopsy
382:spleen
285:, and
243:, and
217:cancer
183:Deaths
7313:Other
7183:CD30+
6929:CD138
6900:CD20+
6794:CD79a
6519:ICD-O
6285:Abola
5338:. CNN
5084:Blood
4918:S2CID
4725:S2CID
4208:S2CID
4159:S2CID
4040:S2CID
4014:Blood
3890:S2CID
3468:S2CID
3360:Blood
3337:S2CID
3177:S2CID
3128:S2CID
3081:S2CID
3055:Blood
2854:Blood
2524:S2CID
2481:S2CID
2089:S2CID
1963:team
1549:U.S.
764:(CT)/
758:X-ray
657:C81.9
640:C81.3
614:C81.0
603:-rich
588:C81.2
565:C81.1
540:tumor
527:ICD-O
472:Types
392:liver
357:fever
253:groin
237:fever
94:Fever
7392:CD56
7286:CD30
7265:CD30
7153:TdT+
7097:T/NK
6962:KSHV
6938:see
6925:CD38
6916:PCDs
6880:CD30
6876:CD15
6851:MALT
6763:CD22
6704:TdT+
6681:CD20
6676:CD19
6543:5973
6527:MeSH
6508:9-CM
6483:2B30
6410:OCLC
6400:ISBN
6348:2023
6293:2021
6248:2021
6200:2020
6148:2015
6122:2015
6086:2020
6025:2015
5998:2013
5972:2023
5943:2023
5893:2009
5801:ISBN
5761:2023
5713:2021
5684:2021
5655:2017
5555:2009
5482:ISBN
5461:2024
5448:ISBN
5427:2024
5405:2024
5383:2021
5318:PMID
5268:PMID
5231:ISBN
5173:2014
5110:PMID
5061:PMID
5011:2014
4975:ISBN
4952:2009
4910:PMID
4866:PMID
4817:PMID
4766:PMID
4717:PMID
4675:PMID
4626:PMID
4577:PMID
4555:2015
4528:PMID
4496:PMID
4455:PMID
4381:PMID
4345:PMID
4306:PMID
4257:PMID
4200:PMID
4151:PMID
4106:PMID
4075:PMID
4032:PMID
3991:PMID
3931:PMID
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