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Itopride

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There is evidence that itopride may have prokinetic effects throughout the gastrointestinal tract from the stomach to the end of the colon. The pharmacokinetics of itopride appear to differ between Asian and Caucasian populations, with Caucasians having 30-50 percent lower blood levels of itopride
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Central nervous system adverse effects do not tend to occur due to poor penetration across the blood brain barrier, although a slight raising of prolactin levels may occur. Raising of prolactin levels is more common with high dose regimes of itopride.
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Chiba T, Tokunaga Y, Ikeda K, Takagi R, Chishima R, Terui T, et al. (September 2007). "Effects of itopride hydrochloride and ranitidine in patients with functional dyspepsia: comparison between prokinetic and acid suppression therapies".
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after 8 weeks of treatment with itopride indicated that itopride was significantly superior to placebo and that itopride yielded a greater rate of response than placebo in significantly reducing pain and fullness.
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After oral administration itopride undergoes rapid and extensive absorption with levels of itopride peaking in the blood plasma after only 35 minutes. Itopride is primarily eliminated via the kidneys having an
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Later, in a study conducted with healthy adult volunteers, itopride was shown as unlikely to cause cardiac arrhythmias or ECG changes in part to the lack of significant interaction and metabolism via the
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also supported the cardiac safety profile of itopride, as it did not affect certain potassium mechanisms that may have been affected by cisapride or mosapride. Moreover, itopride has no affinity for the
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Morisawa T, Hasegawa J, Hama R, Kitano M, Kishimoto Y, Kawasaki H (1999). "Effects of itopride hydrochloride on the delayed rectifier K+ and L-type CA2+ currents in guinea-pig ventricular myocytes".
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Katagiri F, Shiga T, Inoue S, Sato Y, Itoh H, Takeyama M (2006). "Effects of itopride hydrochloride on plasma gut-regulatory peptide and stress-related hormone levels in healthy human subjects".
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regulation issues. Itopride should be used with special caution in the young and the elderly. Little information is available at this time regarding the safe use of itopride during pregnancy.
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Stevens JE, Russo A, Maddox AF, Rayner CK, Phillips L, Talley NJ, et al. (May 2008). "Effect of itopride on gastric emptying in longstanding diabetes mellitus".
1749:"Formulation development and optimization of sustained release matrix tablet of Itopride HCl by response surface methodology and its evaluation of release kinetics" 563: 5995: 4739: 571: 60: 964:
after oral administration. Itopride poorly penetrates across the blood brain barrier because of its high polarity and thus itopride does not tend to cause any
585: 1028:, increases the lower esophageal sphincter pressure, stimulates gastric motility, accelerates gastric emptying, and improves gastro-duodenal coordination. 4194: 630:
as HCl: InChI=1S/C20H26N2O4.ClH/c1-22(2)11-12-26-17-8-5-15(6-9-17)14-21-20(23)16-7-10-18(24-3)19(13-16)25-4;/h5-10,13H,11-12,14H2,1-4H3,(H,21,23);1H
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The most common side-effects of itopride include mild to moderate abdominal pain and diarrhoea. Some other side effects that may occur include:
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Itopride was shown to significantly improve symptoms in patients with functional dyspepsia and motility disorders in placebo-controlled trials.
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InChI=1S/C20H26N2O4/c1-22(2)11-12-26-17-8-5-15(6-9-17)14-21-20(23)16-7-10-18(24-3)19(13-16)25-4/h5-10,13H,11-12,14H2,1-4H3,(H,21,23)
611: 183: 179: 2600: 3095: 1149:(Apex Pharmaceuticals, Nepal) and others. In Mexico, itopride (50 mg) is sold by Takeda Laboratories under the brand name 5585: 4616: 929:. Therefore, it may be possible that itopride could be considered as a better and certainly safer prokinetic agent than either 233: 122: 6221: 2634: 1173: 957: 705: 2560: 3310: 6236: 2610: 6291: 6167: 4158: 3897: 2511: 2300: 354: 2595: 3105: 2128: 1044: 450: 794:
use in either the US nor the UK. However, this does not necessarily indicate that itopride is not effective or safe.
2605: 854:, a reduction in the normal level of white blood cells, can be a potentially life-threatening reaction to itopride. 5490: 4591: 3790: 3768: 2430: 2192: 2570: 2555: 2539: 2360: 2575: 6296: 3985: 3638: 3535: 3260: 1153:. In Bulgaria and other countries of East Europe itopride (50 mg) is sold by Zentiva under the brand name 4929: 1868: 6276: 5009: 2565: 2034: 1232:"Gastroprokinetic effect of a new benzamide derivative itopride and its action mechanisms in conscious dogs" 78: 489: 5395: 4571: 2044: 965: 813: 439: 163: 5741: 5015: 4682: 3903: 3824: 2350: 2321: 1945: 1885: 993: 791: 4068: 4064: 4060: 4056: 4033: 4029: 5990: 5201: 4472: 3753: 3100: 2620: 2580: 2074: 1021: 1017: 778: 690: 195: 6025: 4452: 2473: 6271: 6130: 5406: 4863: 4673: 4502: 4305: 3914: 3880: 3814: 3743: 3560: 3510: 3035: 2835: 2693: 2396: 2367: 2012: 1094: 953: 922:
receptors in the heart has been implicated in the undesirable cardiac effects of cisapride itself.
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Itopride is a relatively new drug and it is not currently approved for normal prescribed use nor
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Typically, itopride is indicated in the treatment of GI symptoms caused by reduced GI motility:
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A blister package of Ganaton (Itopride) 50 mg tablets intended for distribution in the
506: 270: 262: 138: 3245: 1839: 1630:"Effect of itopride hydrochloride on the ileal and colonic motility in guinea pig in vitro" 371: 363: 6250: 5591: 5581: 5561: 5431: 5341: 4612: 4562: 4527: 4522: 4052: 4021: 3935: 3930: 3738: 3025: 3015: 2995: 2265: 1055: 1040: 887: 729: 343: 173: 146: 493: 470: 1857: 925:
The conclusion of this study revealed that itopride is devoid of any abnormal effect on
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Patients taking itopride should report any side-effects to their treating physician.
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Smith DA, Allerton C, Kubinyi H, van de Waterbeemd H, Walker DK, eds. (April 2012).
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of a non-ulcer/dysmotility type (gastric "fullness", discomfort, and possible pain)
105: 100: 1875: 1180: 1553:"Effect of itopride, a new prokinetic, in patients with mild GERD: a pilot study" 295: 6080: 6065: 6050: 5913: 5883: 5878: 5873: 5843: 5817: 5812: 5807: 5782: 5777: 5762: 5752: 5732: 5727: 5712: 5702: 5697: 5687: 5667: 5652: 5632: 5617: 5571: 5506: 5481: 5471: 5466: 5461: 5416: 5391: 5361: 5311: 5271: 5216: 5211: 5191: 5156: 5141: 5131: 5121: 5101: 5091: 5035: 4950: 4873: 4868: 4853: 4806: 4713: 4708: 4698: 4663: 4638: 4607: 4567: 4447: 4392: 4366: 4356: 4295: 4107: 3945: 3865: 3809: 3703: 3648: 3550: 3315: 3215: 3090: 3045: 2889: 2884: 2879: 2812: 2773: 2718: 2703: 2683: 2668: 2440: 2417: 2338: 2295: 2290: 2255: 2184: 2138: 2084: 2079: 2059: 2049: 2002: 1025: 946: 926: 879: 875: 694: 4179: 1764: 6085: 6075: 6070: 6055: 6010: 6005: 5934: 5863: 5858: 5848: 5802: 5797: 5787: 5772: 5767: 5737: 5707: 5677: 5657: 5576: 5546: 5386: 5381: 5376: 5371: 5366: 5346: 5316: 5306: 5266: 5261: 5256: 5251: 5236: 5221: 5176: 5171: 5166: 5161: 5126: 5116: 5111: 5096: 5020: 4984: 4945: 4924: 4878: 4832: 4796: 4744: 4693: 4678: 4643: 4552: 4482: 4477: 4462: 4457: 4410: 4387: 4361: 4346: 4300: 4274: 4269: 4264: 4259: 4254: 4249: 4132: 4128: 3860: 3850: 3845: 3758: 3733: 3693: 3688: 3678: 3663: 3604: 3599: 3410: 3270: 3255: 3225: 3200: 3175: 3130: 3125: 3115: 3085: 3055: 2919: 2909: 2854: 2849: 2820: 2797: 2763: 2728: 2713: 2678: 2653: 2507: 2452: 2412: 2407: 2402: 2387: 2285: 2250: 2245: 2225: 2148: 2143: 1997: 1982: 1972: 1645: 1134: 1118: 1114: 911: 851: 809: 801: 675: 539: 334: 1604:"Effect Of Itopride hydrochloride on QT interval in adult healthy volunteers" 1569: 1403: 323: 6145: 6125: 6090: 6035: 6030: 5985: 5939: 5929: 5722: 5717: 5662: 5622: 5541: 5531: 5521: 5511: 5426: 5301: 5241: 5231: 5206: 5196: 5186: 5146: 5086: 5081: 5000: 4955: 4898: 4893: 4827: 4822: 4817: 4801: 4759: 4754: 4648: 4633: 4532: 4497: 4397: 4325: 4320: 3971: 3855: 3804: 3713: 3708: 3698: 3540: 3475: 3470: 3460: 3415: 3385: 3380: 3365: 3350: 3320: 3285: 3275: 3180: 3060: 3050: 3040: 3010: 3005: 3000: 2924: 2899: 2864: 2793: 2768: 2738: 2698: 2648: 2462: 2445: 2280: 2202: 2179: 2024: 1962: 980: 934: 930: 895: 891: 871: 867: 805: 756: 740: 678: 208: 64: 1817: 1782: 1733: 1698: 1663: 1588: 1551:
Kim YS, Kim TH, Choi CS, Shon YW, Kim SW, Seo GS, et al. (July 2005).
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receptor antagonists, itopride has been found to dose-dependently increase
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Itopride given as a single dose study found that it also raises levels of
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These studies concluded that the reduction in the severity of symptoms of
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Holtmann G, Talley NJ, Liebregts T, Adam B, Parow C (February 2006).
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Holtmann G, Talley NJ, Liebregts T, Adam B, Parow C (February 2006).
1142: 1126: 430: 213: 1004: 28: 832:, giddiness, exhaustion, back or chest pain, increased salivation, 399: 391: 5960: 5061: 3778: 3500: 3490: 3340: 3235: 2585: 1077: 1003: 570: 562: 553: 410: 1230:
Iwanaga Y, Miyashita N, Saito T, Morikawa K, Itoh Z (June 1996).
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other possible gastric, prolactin, or dopamine related conditions
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for "Itopride in Functional Dyspepsia:a Dose Finding Study" at
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Research Communications in Molecular Pathology and Pharmacology
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Itopride is contraindicated in hypersensitivity to itopride or
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Irritable Bowel Syndrome, an Issue of Gastroenterology Clinics
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Ganaton (Itopride) 50 mg tablets. Engraving says "HC 803"
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as HCl: Cl.COC1=CC=C(C=C1OC)C(=O)NCC1=CC=C(OCCN(C)C)C=C1
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Octamethylene-bis(5-dimethylcarbamoxyisoquinolinium bromide)
1387:"Itopride therapy for functional dyspepsia: a meta-analysis" 455: 4043: 3956: 2976:
2-Ethoxycarbonyl-1-methylvinyl cyclohexyl methylphosphonate
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Gastroparesis: Pathophysiology, Presentation and Treatment
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Huang X, Lv B, Zhang S, Fan YH, Meng LN (December 2012).
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Kojecky V, Bernatek J, Bakala J, Weissova D (2005). "".
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and other gastrointestinal conditions. It is a combined
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Lim HC, Kim YG, Lim JH, Kim HS, Park H (June 2008).
5280: 4785: 4772: 4541: 4511: 4233: 4220: 4097: 4001: 3984: 3954: 3913: 3896: 3823: 2619: 2538: 2521: 2386: 2313: 2213: 2157: 2127: 2011: 1953: 1944: 1929: 689:effect. Itopride is indicated for the treatment of 551: 538: 505: 500: 481: 449: 429: 409: 381: 353: 333: 305: 280: 252: 224: 207: 194: 172: 162: 145: 137: 121: 116: 91: 77: 59: 49: 44: 1209:(3rd ed.). Weinheim: Wiley-VCH. p. 132. 878:and possibly predispose those using it to cardiac 2540: 6287:Drugs developed by Takeda Pharmaceutical Company 294: 914:such as cisapride and mosapride, which are 5-HT 593:CN(C)CCOC1=CC=C(C=C1)CNC(=O)C2=CC(=C(C=C2)OC)OC 269: 261: 3885:Many of the other AChE inhibitors listed above 1342: 1340: 1338: 1207:Pharmacokinetics and Metabolism in Drug Design 4195: 3825: 2489: 1901: 1602:Gupta S, Kapoor V, Gupta BM, Verma U (2005). 685:and acetylcholine esterase enzyme and have a 8: 4941:Deoxyepinephrine (N-methyldopamine, epinine) 4383:Deoxyepinephrine (N-methyldopamine, epinine) 4164:Muscarinic acetylcholine receptor modulators 2621: 1380: 1378: 1376: 1374: 1372: 1370: 1071:Itopride is available under the brand names 918:agonists. The affinity of cisapride for 5-HT 635:Key:ZTOUXLLIPWWHSR-UHFFFAOYSA-N-UHFFFAOYSA-N 19: 4169:Nicotinic acetylcholine receptor modulators 4048:Tooltip Vesicle-associated membrane protein 3961:Tooltip Vesicular acetylcholine transporter 3915: 1353:. Elsevier Health Sciences. pp. 232–. 968:adverse effects. Itopride has no effect on 130:In general: ℞ (Prescription only) 4782: 4230: 4202: 4188: 4180: 4017:Tooltip Synaptosomal-associated protein 25 3998: 3910: 2535: 2496: 2482: 2474: 1950: 1941: 1908: 1894: 1886: 1315:Parkman HP, McCallum RW (5 October 2011). 492: 469: 342: 1772: 1653: 1578: 1568: 1527: 1412: 1402: 1288: 1247: 370: 362: 747:gastroparesis (delayed gastric emptying) 723: 6241: 5830:Antiemetics/gastroprokinetics/sedatives 3121:Dimethyl 4-(methylthio)phenyl phosphate 1747:Bose A, Wong TW, Singh N (April 2013). 1179:. Abbott Japan Co., Ltd. Archived from 1165: 616: 590: 465: 322: 314: 238: 1058:agents reduce the action of itopride. 483: 18: 3311:Methylfluorophosphonylcholine (MFPCh) 2561:2-(α-Naphthoyl)ethyltrimethylammonium 1918:functional gastrointestinal disorders 438: 418: 69: 7: 1864:. U.S. National Library of Medicine. 1024:. Higher acetylcholine increases GI 104: 5432:Levomepromazine (methotrimeprazine) 4108: 2611:N,N-Dimethylaminoethylchloroacetate 2241:Dimethylaminopropionylphenothiazine 1516:The New England Journal of Medicine 1277:The New England Journal of Medicine 398: 390: 285: 1679:Neurogastroenterology and Motility 945:Itopride acts as a selective dual 14: 2545:Tooltip Choline acetyltransferase 1557:World Journal of Gastroenterology 1493:Ces.Slov.Gastroent.Hepatol., 2005 1391:World Journal of Gastroenterology 840:, sleeping disorders, dizziness, 786:Contraindications and precautions 6244: 3605:Fasciculins (green mamba toxins) 3096:Dicyclohexyl phosphorofluoridate 1691:10.1111/j.1365-2982.2007.01058.x 1236:Japanese Journal of Pharmacology 681:derivative. These drugs inhibit 523: 517: 36: 27: 6267:Acetylcholinesterase inhibitors 6213:Monoamine metabolism modulators 3536:Tetraethyl pyrophosphate (TEPP) 3261:Hexaethyl tetraphosphate (HETP) 624:Key:QQQIECGTIMUVDS-UHFFFAOYSA-N 244:-methyl]-3,4-dimethoxybenzamide 2606:N,N-Dimethylaminoethylacrylate 2397:Primarily dopamine antagonists 2346:Quaternary ammonium compounds: 958:acetylcholinesterase inhibitor 816:or other conditions involving 706:acetylcholinesterase inhibitor 529: 511: 1: 6195:Monoamine reuptake inhibitors 6168:Receptor/signaling modulators 4347:Adrogolide (ABT-431, DAS-431) 4159:Receptor/signaling modulators 3931:Hemicholinium-3 (hemicholine) 3830:Tooltip Butyrylcholinesterase 1016:concentrations by inhibiting 866:Itopride belongs to the same 6302:Peripherally selective drugs 2626:Tooltip Acetylcholinesterase 2301:Trimethyldiphenylpropylamine 1753:Saudi Pharmaceutical Journal 3920:Tooltip Choline transporter 3866:Profenamine (ethopropazine) 3106:Diisopropyl fluorophosphate 2571:4-(1-Naphthylvinyl)pyridine 2556:1-(-Benzoylethyl)pyridinium 1321:. Springer. pp. 264–. 1145:), PRO.MED.CS Praha a.s.), 1045:adrenocorticotropic hormone 712:is the dimethoxy analog of 6318: 6204:Monoamine releasing agents 5392:Flupentixol (flupenthixol) 4568:Flupentixol (flupenthixol) 3769:Dimethylcarbamoyl fluoride 2576:Acetylseco hemicholinium-3 1765:10.1016/j.jsps.2012.03.006 996:of approximately 6 hours. 501:Chemical and physical data 6282:Drugs developed by AbbVie 6158: 6056:Metitepine (methiothepin) 5482:Pericyazine (periciazine) 4906:Dihydrexidine derivatives 4745:Metitepine (methiothepin) 4333:Dihydrexidine derivatives 4151: 1646:10.3349/ymj.2008.49.3.472 1347:Chey WY, Chey WD (2011). 874:, a drug found to affect 643: 607: 581: 229: 35: 26: 5658:Clotiapine (clothiapine) 5532:Spiperone (spiroperidol) 5497:Piflutixol (pifluthixol) 3639:Methanesulfonyl fluoride 1570:10.3748/wjg.v11.i27.4210 1472:(5): 358, 360–358, 362. 1404:10.3748/wjg.v18.i48.7371 910:receptors, unlike other 71:International Drug Names 5614:Atypical antipsychotics 4997:Atypical antipsychotics 4930:N,N-Propyldihydrexidine 4630:Atypical antipsychotics 4519:Tetrahydroisoquinolines 2816:+glycopyrronium bromide 1862:Drug Information Portal 1464:Keil R (May 2004). "". 1439:Hepato-Gastroenterology 890:enzyme pathway, unlike 5288:Typical antipsychotics 4549:Typical antipsychotics 2566:3-Chloro-4-stillbazole 1873:Clinical trial number 1634:Yonsei Medical Journal 1009: 966:central nervous system 824:Adverse drug reactions 733: 6222:Monoamine neurotoxins 5016:Aripiprazole lauroxil 1869:Abbott Labs "Ganaton" 1039:and lowers levels of 1018:dopamine D2 receptors 1007: 994:elimination half-life 727: 5991:Desmethoxyfallypride 5202:Propylnorapomorphine 5001:Alentemol (U-66444B) 4473:Propylnorapomorphine 4127:Atracotoxins (e.g., 3754:Tetrahydrocannabinol 3101:Diisopropylphosphate 1529:10.1056/NEJMoa052639 1290:10.1056/NEJMoa052639 1022:acetylcholinesterase 975:Similarly to other D 779:functional dyspepsia 691:functional dyspepsia 6292:Motility stimulants 6131:Tetrahydropalmatine 4864:Dihydroergocryptine 4503:Tetrahydropalmatine 4306:Dihydroergocryptine 4113:Tooltip Latrophilin 3815:Trimedoxime bromide 3744:Stercuronium iodide 3561:Tricresyl phosphate 3036:Chlorpyrifos-methyl 2368:Cimetropium bromide 2161:serotonin receptors 1186:on 11 December 2015 1095:Abbott Laboratories 1062:Society and culture 1012:Itopride increases 1000:Mechanism of action 814:Parkinson's disease 767:nausea and vomiting 178:Extensive hepatic ( 23: 3632:Onchidella binneyi 2974:Organophosphates: 2276:Pinaverium bromide 1881:ClinicalTrials.gov 1249:10.1254/jjp.71.129 1010: 970:potassium channels 734: 6232: 6231: 6225: 6216: 6207: 6198: 6189: 6180: 6171: 6154: 6153: 6061:N-Methylspiperone 5919:Trimethobenzamide 4979: 4971: 4963: 4768: 4767: 4426: 4418: 4405: 4211:Dopamine receptor 4177: 4176: 4147: 4146: 3995: 3980: 3979: 3907: 3892: 3891: 3531:Tetrachlorvinphos 3406:Pirimiphos-methyl 3356:Oxydemeton-methyl 3306:Methyl phenkapton 2532: 2471: 2470: 2373:Fentonium bromide 2361:Methylscopolamine 2309: 2308: 2129:Phosphodiesterase 2123: 2122: 1810:10.1159/000093485 1563:(27): 4210–4214. 1466:Vnitrni Lekarstvi 1445:(78): 1878–1881. 1397:(48): 7371–7377. 1360:978-1-4557-0450-7 1328:978-1-60761-552-1 1216:978-3-527-32954-0 1092: 1086: 1080: 714:trimethobenzamide 661: 660: 572:Interactive image 564:Interactive image 451:CompTox Dashboard 16:Chemical compound 6309: 6249: 6248: 6247: 6240: 6219: 6210: 6201: 6192: 6183: 6174: 6162: 6041:Levofenfluramine 5909:Thiethylperazine 5586:+tranylcypromine 5517:Prochlorperazine 5332:Chlorproethazine 4977: 4969: 4964:-DOPA (levodopa) 4961: 4783: 4617:+tranylcypromine 4424: 4416: 4406:-DOPA (levodopa) 4403: 4231: 4204: 4197: 4190: 4181: 4114: 4110: 4049: 4045: 4018: 4014: 3999: 3989: 3962: 3958: 3921: 3917: 3911: 3901: 3831: 3827: 3795:Asoxime chloride 3371:Parathion-methyl 3071:Demeton-S-methyl 2627: 2623: 2546: 2542: 2536: 2526: 2498: 2491: 2484: 2475: 2356:Butylscopolamine 2331:Tertiary amines: 2231:Chlorbenzoxamine 1988:Oxyphencyclimine 1951: 1942: 1910: 1903: 1896: 1887: 1865: 1844: 1843: 1836: 1830: 1829: 1793: 1787: 1786: 1776: 1744: 1738: 1737: 1717: 1711: 1710: 1674: 1668: 1667: 1657: 1625: 1619: 1618: 1608: 1599: 1593: 1592: 1582: 1572: 1548: 1542: 1541: 1531: 1507: 1501: 1500: 1488: 1482: 1481: 1461: 1455: 1454: 1433: 1427: 1426: 1416: 1406: 1382: 1365: 1364: 1344: 1333: 1332: 1312: 1303: 1302: 1292: 1268: 1262: 1261: 1251: 1227: 1221: 1220: 1202: 1196: 1195: 1193: 1191: 1185: 1178: 1170: 1088: 1082: 1076: 987:Pharmacokinetics 657: 656: 649: 574: 566: 546: 531: 525: 519: 513: 496: 485: 474: 473: 459: 457: 442: 422: 402: 394: 374: 366: 346: 326: 318: 298: 288: 287: 273: 265: 199: 108: 73: 40: 31: 24: 22: 6317: 6316: 6312: 6311: 6310: 6308: 6307: 6306: 6297:Catechol ethers 6257: 6256: 6255: 6245: 6243: 6235: 6233: 6228: 6150: 5926:Antidepressants 5592:Triflupromazine 5582:Trifluoperazine 5562:Thioproperazine 5342:Chlorprothixene 5276: 4937:Phenethylamines 4777: 4764: 4613:Trifluoperazine 4563:Chlorprothixene 4537: 4507: 4374:Phenethylamines 4225: 4216: 4208: 4178: 4173: 4143: 4112: 4093: 4053:Botulinum toxin 4047: 4022:Botulinum toxin 4016: 3988: 3976: 3960: 3950: 3936:Triethylcholine 3919: 3900: 3888: 3829: 3819: 3739:Rosmarinic acid 3506:Sulfotep (TEDP) 3176:Ethylsarin (GE) 3056:Cyclosarin (GF) 3026:Chlorfenvinphos 3016:Carbophenothion 2996:Azinphos-methyl 2625: 2615: 2581:Acryloylcholine 2544: 2525: 2517: 2502: 2472: 2467: 2434: 2382: 2322:antimuscarinics 2319: 2318:and derivatives 2317: 2305: 2266:Mentha piperita 2209: 2196: 2173: 2159: 2153: 2130: 2119: 2017: 2014: 2007: 1955: 1946:Antimuscarinics 1936: 1934: 1931: 1925: 1914: 1856: 1853: 1848: 1847: 1838: 1837: 1833: 1795: 1794: 1790: 1746: 1745: 1741: 1719: 1718: 1714: 1676: 1675: 1671: 1627: 1626: 1622: 1611:JK-Practitioner 1606: 1601: 1600: 1596: 1550: 1549: 1545: 1509: 1508: 1504: 1490: 1489: 1485: 1463: 1462: 1458: 1435: 1434: 1430: 1384: 1383: 1368: 1361: 1346: 1345: 1336: 1329: 1314: 1313: 1306: 1270: 1269: 1265: 1229: 1228: 1224: 1217: 1204: 1203: 1199: 1189: 1187: 1183: 1176: 1172: 1171: 1167: 1162: 1069: 1064: 1056:Anticholinergic 1053: 1041:cholecystokinin 1002: 989: 978: 950: 943: 921: 917: 908: 888:cytochrome P450 864: 862:Cardiac studies 826: 788: 730:Slovak Republic 722: 698: 652: 650: 647:(what is this?) 644: 639: 636: 631: 628: 625: 620: 615: 614: 603: 600: 597: 594: 589: 588: 577: 544: 534: 528: 522: 516: 477: 453: 445: 425: 405: 377: 349: 329: 301: 284: 276: 248: 245: 237: 236: 197: 164:Protein binding 156: 147:Bioavailability 139:Pharmacokinetic 133: 112: 80: 17: 12: 11: 5: 6315: 6313: 6305: 6304: 6299: 6294: 6289: 6284: 6279: 6277:D2 antagonists 6274: 6269: 6259: 6258: 6254: 6253: 6230: 6229: 6227: 6226: 6217: 6208: 6199: 6190: 6181: 6172: 6159: 6156: 6155: 6152: 6151: 6149: 6148: 6143: 6138: 6133: 6128: 6123: 6118: 6113: 6108: 6103: 6098: 6093: 6088: 6083: 6078: 6073: 6068: 6063: 6058: 6053: 6048: 6043: 6038: 6033: 6028: 6026:Isocorypalmine 6023: 6018: 6013: 6008: 6003: 5998: 5993: 5988: 5983: 5978: 5973: 5968: 5963: 5953: 5952: 5947: 5942: 5937: 5932: 5922: 5921: 5916: 5911: 5906: 5901: 5896: 5894:Metoclopramide 5891: 5886: 5881: 5876: 5871: 5869:Deudomperidone 5866: 5861: 5856: 5851: 5846: 5841: 5836: 5834:Aceprometazine 5826: 5825: 5820: 5815: 5810: 5805: 5800: 5795: 5790: 5785: 5780: 5775: 5770: 5765: 5760: 5758:Piperacetazine 5755: 5750: 5745: 5735: 5730: 5725: 5720: 5715: 5710: 5705: 5700: 5695: 5690: 5685: 5680: 5675: 5670: 5665: 5660: 5655: 5650: 5645: 5640: 5635: 5630: 5625: 5620: 5610: 5609: 5607:Zuclopenthixol 5604: 5599: 5594: 5589: 5579: 5574: 5569: 5564: 5559: 5554: 5549: 5544: 5539: 5534: 5529: 5524: 5519: 5514: 5509: 5504: 5499: 5494: 5491:+amitriptyline 5484: 5479: 5474: 5469: 5464: 5459: 5454: 5449: 5444: 5439: 5434: 5429: 5424: 5419: 5414: 5409: 5404: 5399: 5389: 5384: 5379: 5374: 5369: 5364: 5359: 5354: 5349: 5344: 5339: 5337:Chlorpromazine 5334: 5329: 5324: 5319: 5314: 5309: 5304: 5299: 5297:Acetophenazine 5294: 5284: 5282: 5278: 5277: 5275: 5274: 5269: 5264: 5259: 5254: 5249: 5244: 5239: 5234: 5229: 5224: 5219: 5214: 5209: 5204: 5199: 5194: 5189: 5184: 5179: 5174: 5169: 5164: 5159: 5154: 5149: 5144: 5139: 5134: 5129: 5124: 5119: 5114: 5109: 5104: 5099: 5094: 5089: 5084: 5079: 5074: 5069: 5064: 5054: 5053: 5048: 5043: 5038: 5033: 5028: 5023: 5018: 5013: 5003: 4993: 4992: 4987: 4982: 4974: 4972:-Phenylalanine 4966: 4958: 4953: 4948: 4943: 4933: 4932: 4927: 4922: 4917: 4912: 4902: 4901: 4896: 4891: 4886: 4881: 4876: 4871: 4866: 4861: 4856: 4851: 4841: 4840: 4835: 4830: 4825: 4820: 4814:Aminotetralins 4810: 4809: 4804: 4799: 4789: 4787: 4780: 4775: 4770: 4769: 4766: 4765: 4763: 4762: 4757: 4752: 4747: 4742: 4737: 4732: 4722: 4721: 4716: 4711: 4706: 4701: 4696: 4691: 4686: 4676: 4671: 4666: 4661: 4656: 4651: 4646: 4641: 4636: 4626: 4625: 4623:Zuclopenthixol 4620: 4610: 4605: 4600: 4595: 4592:+amitriptyline 4585: 4580: 4575: 4565: 4560: 4558:Chlorpromazine 4555: 4545: 4543: 4539: 4538: 4536: 4535: 4530: 4525: 4515: 4513: 4509: 4508: 4506: 4505: 4500: 4495: 4490: 4485: 4480: 4475: 4470: 4465: 4460: 4455: 4453:Isocorypalmine 4450: 4445: 4435: 4434: 4429: 4421: 4419:-Phenylalanine 4413: 4408: 4400: 4395: 4390: 4385: 4380: 4370: 4369: 4364: 4359: 4354: 4349: 4344: 4339: 4329: 4328: 4323: 4318: 4313: 4308: 4303: 4298: 4288: 4287: 4282: 4277: 4272: 4267: 4262: 4257: 4252: 4247: 4237: 4235: 4228: 4223: 4218: 4217: 4209: 4207: 4206: 4199: 4192: 4184: 4175: 4174: 4172: 4171: 4166: 4161: 4156: 4152: 4149: 4148: 4145: 4144: 4142: 4141: 4136: 4121: 4120: 4103: 4101: 4095: 4094: 4092: 4091: 4088:γ-bungarotoxin 4084:β-bungarotoxin 4073: 4072: 4038: 4037: 4007: 4005: 3996: 3982: 3981: 3978: 3977: 3975: 3974: 3965: 3963: 3952: 3951: 3949: 3948: 3939: 3938: 3933: 3924: 3922: 3908: 3894: 3893: 3890: 3889: 3887: 3886: 3883: 3878: 3873: 3868: 3863: 3858: 3853: 3848: 3843: 3834: 3832: 3821: 3820: 3818: 3817: 3812: 3807: 3802: 3797: 3787: 3786: 3781: 3776: 3771: 3766: 3761: 3756: 3751: 3746: 3741: 3736: 3731: 3726: 3721: 3716: 3711: 3706: 3701: 3696: 3691: 3686: 3681: 3676: 3671: 3666: 3661: 3656: 3651: 3642: 3641: 3636: 3624: 3602: 3593: 3588: 3583: 3578: 3573: 3568: 3563: 3558: 3553: 3548: 3543: 3538: 3533: 3528: 3523: 3518: 3513: 3508: 3503: 3498: 3493: 3488: 3483: 3478: 3473: 3468: 3463: 3458: 3453: 3448: 3443: 3438: 3433: 3428: 3423: 3418: 3413: 3408: 3403: 3398: 3393: 3388: 3383: 3378: 3373: 3368: 3363: 3358: 3353: 3348: 3346:Novichok agent 3343: 3338: 3333: 3328: 3323: 3318: 3313: 3308: 3303: 3298: 3293: 3288: 3283: 3278: 3273: 3268: 3266:Isofluorophate 3263: 3258: 3253: 3248: 3243: 3238: 3233: 3228: 3223: 3218: 3213: 3208: 3203: 3198: 3193: 3188: 3183: 3178: 3173: 3168: 3163: 3158: 3153: 3148: 3143: 3138: 3133: 3128: 3123: 3118: 3113: 3108: 3103: 3098: 3093: 3088: 3083: 3078: 3073: 3068: 3063: 3058: 3053: 3048: 3043: 3038: 3033: 3028: 3023: 3021:Chlorethoxyfos 3018: 3013: 3008: 3003: 2998: 2993: 2991:Azinphos-ethyl 2988: 2983: 2978: 2968: 2967: 2962: 2957: 2952: 2947: 2942: 2937: 2932: 2927: 2922: 2917: 2912: 2907: 2902: 2897: 2892: 2887: 2882: 2877: 2872: 2867: 2862: 2857: 2852: 2843: 2838: 2833: 2831:Pyridostigmine 2828: 2823: 2818: 2810: 2805: 2800: 2791: 2786: 2781: 2776: 2771: 2766: 2761: 2756: 2751: 2746: 2741: 2736: 2731: 2726: 2721: 2716: 2711: 2706: 2701: 2696: 2691: 2686: 2681: 2676: 2671: 2666: 2661: 2656: 2651: 2646: 2630: 2628: 2617: 2616: 2614: 2613: 2608: 2603: 2598: 2593: 2588: 2583: 2578: 2573: 2568: 2563: 2558: 2549: 2547: 2533: 2519: 2518: 2503: 2501: 2500: 2493: 2486: 2478: 2469: 2468: 2466: 2465: 2460: 2455: 2450: 2449: 2448: 2443: 2432: 2427: 2426: 2425: 2423:Metoclopramide 2420: 2415: 2410: 2405: 2392: 2390: 2384: 2383: 2381: 2380: 2378:Methylatropine 2375: 2370: 2365: 2364: 2363: 2358: 2353: 2342: 2341: 2336: 2327: 2325: 2311: 2310: 2307: 2306: 2304: 2303: 2298: 2293: 2288: 2283: 2278: 2273: 2271:Phloroglucinol 2268: 2263: 2258: 2253: 2248: 2243: 2238: 2233: 2228: 2223: 2217: 2215: 2211: 2210: 2208: 2207: 2206: 2205: 2194: 2189: 2188: 2187: 2182: 2171: 2165: 2163: 2155: 2154: 2152: 2151: 2146: 2141: 2135: 2133: 2125: 2124: 2121: 2120: 2118: 2117: 2112: 2107: 2102: 2097: 2092: 2087: 2082: 2077: 2072: 2067: 2062: 2057: 2052: 2047: 2045:Glycopyrronium 2042: 2037: 2032: 2027: 2021: 2019: 2009: 2008: 2006: 2005: 2000: 1995: 1990: 1985: 1980: 1975: 1970: 1965: 1959: 1957: 1948: 1939: 1927: 1926: 1915: 1913: 1912: 1905: 1898: 1890: 1884: 1883: 1871: 1866: 1852: 1851:External links 1849: 1846: 1845: 1831: 1804:(3): 115–121. 1788: 1759:(2): 201–213. 1739: 1728:(1–2): 37–45. 1712: 1685:(5): 456–463. 1669: 1640:(3): 472–478. 1620: 1594: 1543: 1522:(8): 832–840. 1502: 1483: 1456: 1428: 1366: 1359: 1334: 1327: 1304: 1283:(8): 832–840. 1263: 1242:(2): 129–137. 1222: 1215: 1197: 1164: 1163: 1161: 1158: 1068: 1065: 1063: 1060: 1052: 1049: 1001: 998: 988: 985: 976: 948: 942: 939: 919: 915: 906: 863: 860: 825: 822: 787: 784: 772: 771: 768: 765: 762: 759: 754: 749: 744: 721: 718: 696: 659: 658: 641: 640: 638: 637: 634: 632: 629: 626: 623: 621: 618: 610: 609: 608: 605: 604: 602: 601: 598: 595: 592: 584: 583: 582: 579: 578: 576: 575: 567: 559: 557: 549: 548: 542: 536: 535: 532: 526: 520: 514: 509: 503: 502: 498: 497: 487: 479: 478: 476: 475: 462: 460: 447: 446: 444: 443: 435: 433: 427: 426: 424: 423: 415: 413: 407: 406: 404: 403: 395: 387: 385: 379: 378: 376: 375: 367: 359: 357: 351: 350: 348: 347: 339: 337: 331: 330: 328: 327: 319: 311: 309: 303: 302: 300: 299: 291: 289: 278: 277: 275: 274: 266: 258: 256: 250: 249: 247: 246: 240: 232: 231: 230: 227: 226: 222: 221: 211: 205: 204: 201: 192: 191: 176: 170: 169: 166: 160: 159: 154: 149: 143: 142: 135: 134: 132: 131: 127: 125: 119: 118: 114: 113: 111: 110: 97: 95: 89: 88: 83: 81:administration 75: 74: 67: 57: 56: 53: 47: 46: 42: 41: 33: 32: 15: 13: 10: 9: 6: 4: 3: 2: 6314: 6303: 6300: 6298: 6295: 6293: 6290: 6288: 6285: 6283: 6280: 6278: 6275: 6273: 6270: 6268: 6265: 6264: 6262: 6252: 6242: 6238: 6224: 6223: 6218: 6215: 6214: 6209: 6206: 6205: 6200: 6197: 6196: 6191: 6188: 6187: 6186:Serotonergics 6182: 6179: 6178: 6173: 6170: 6169: 6166: 6161: 6160: 6157: 6147: 6144: 6142: 6139: 6137: 6134: 6132: 6129: 6127: 6124: 6122: 6119: 6117: 6114: 6112: 6109: 6107: 6106:Sonepiprazole 6104: 6102: 6099: 6097: 6094: 6092: 6089: 6087: 6084: 6082: 6079: 6077: 6074: 6072: 6069: 6067: 6064: 6062: 6059: 6057: 6054: 6052: 6049: 6047: 6044: 6042: 6039: 6037: 6034: 6032: 6029: 6027: 6024: 6022: 6021:Iodobenzamide 6019: 6017: 6014: 6012: 6009: 6007: 6004: 6002: 5999: 5997: 5994: 5992: 5989: 5987: 5984: 5982: 5981:Bromocriptine 5979: 5977: 5974: 5972: 5969: 5967: 5964: 5962: 5958: 5955: 5954: 5951: 5948: 5946: 5943: 5941: 5938: 5936: 5933: 5931: 5927: 5924: 5923: 5920: 5917: 5915: 5912: 5910: 5907: 5905: 5902: 5900: 5897: 5895: 5892: 5890: 5887: 5885: 5882: 5880: 5877: 5875: 5872: 5870: 5867: 5865: 5862: 5860: 5857: 5855: 5854:Benzquinamide 5852: 5850: 5847: 5845: 5842: 5840: 5837: 5835: 5831: 5828: 5827: 5824: 5821: 5819: 5816: 5814: 5811: 5809: 5806: 5804: 5801: 5799: 5796: 5794: 5791: 5789: 5786: 5784: 5781: 5779: 5776: 5774: 5771: 5769: 5766: 5764: 5761: 5759: 5756: 5754: 5751: 5749: 5746: 5743: 5739: 5736: 5734: 5731: 5729: 5726: 5724: 5721: 5719: 5716: 5714: 5711: 5709: 5706: 5704: 5701: 5699: 5696: 5694: 5691: 5689: 5686: 5684: 5681: 5679: 5676: 5674: 5673:DHA-clozapine 5671: 5669: 5666: 5664: 5661: 5659: 5656: 5654: 5651: 5649: 5646: 5644: 5641: 5639: 5636: 5634: 5631: 5629: 5626: 5624: 5621: 5619: 5615: 5612: 5611: 5608: 5605: 5603: 5600: 5598: 5597:Trifluperidol 5595: 5593: 5590: 5587: 5583: 5580: 5578: 5575: 5573: 5570: 5568: 5565: 5563: 5560: 5558: 5557:Thiopropazate 5555: 5553: 5550: 5548: 5545: 5543: 5540: 5538: 5537:Sulforidazine 5535: 5533: 5530: 5528: 5525: 5523: 5520: 5518: 5515: 5513: 5510: 5508: 5505: 5503: 5500: 5498: 5495: 5492: 5488: 5485: 5483: 5480: 5478: 5475: 5473: 5470: 5468: 5465: 5463: 5460: 5458: 5455: 5453: 5450: 5448: 5445: 5443: 5440: 5438: 5437:Levosulpiride 5435: 5433: 5430: 5428: 5425: 5423: 5420: 5418: 5415: 5413: 5410: 5408: 5407:Fluprothixene 5405: 5403: 5400: 5397: 5393: 5390: 5388: 5385: 5383: 5380: 5378: 5375: 5373: 5370: 5368: 5365: 5363: 5360: 5358: 5355: 5353: 5350: 5348: 5345: 5343: 5340: 5338: 5335: 5333: 5330: 5328: 5325: 5323: 5320: 5318: 5315: 5313: 5310: 5308: 5305: 5303: 5300: 5298: 5295: 5293: 5289: 5286: 5285: 5283: 5279: 5273: 5270: 5268: 5265: 5263: 5260: 5258: 5255: 5253: 5250: 5248: 5245: 5243: 5240: 5238: 5235: 5233: 5230: 5228: 5225: 5223: 5220: 5218: 5215: 5213: 5210: 5208: 5205: 5203: 5200: 5198: 5195: 5193: 5190: 5188: 5185: 5183: 5182:Phencyclidine 5180: 5178: 5175: 5173: 5170: 5168: 5165: 5163: 5160: 5158: 5155: 5153: 5150: 5148: 5145: 5143: 5140: 5138: 5135: 5133: 5130: 5128: 5125: 5123: 5120: 5118: 5115: 5113: 5110: 5108: 5105: 5103: 5100: 5098: 5095: 5093: 5090: 5088: 5085: 5083: 5080: 5078: 5075: 5073: 5070: 5068: 5065: 5063: 5059: 5056: 5055: 5052: 5049: 5047: 5044: 5042: 5039: 5037: 5034: 5032: 5031:Brilaroxazine 5029: 5027: 5026:Brexpiprazole 5024: 5022: 5019: 5017: 5014: 5011: 5007: 5004: 5002: 4998: 4995: 4994: 4991: 4988: 4986: 4983: 4981: 4975: 4973: 4967: 4965: 4959: 4957: 4954: 4952: 4949: 4947: 4944: 4942: 4938: 4935: 4934: 4931: 4928: 4926: 4923: 4921: 4920:Dihydrexidine 4918: 4916: 4913: 4911: 4907: 4904: 4903: 4900: 4897: 4895: 4892: 4890: 4887: 4885: 4882: 4880: 4877: 4875: 4872: 4870: 4867: 4865: 4862: 4860: 4857: 4855: 4852: 4850: 4849:Bromocriptine 4846: 4843: 4842: 4839: 4836: 4834: 4831: 4829: 4826: 4824: 4821: 4819: 4815: 4812: 4811: 4808: 4805: 4803: 4800: 4798: 4794: 4791: 4790: 4788: 4784: 4781: 4779: 4771: 4761: 4758: 4756: 4753: 4751: 4748: 4746: 4743: 4741: 4738: 4736: 4733: 4731: 4727: 4724: 4723: 4720: 4717: 4715: 4712: 4710: 4707: 4705: 4702: 4700: 4697: 4695: 4692: 4690: 4687: 4684: 4680: 4677: 4675: 4674:Norquetiapine 4672: 4670: 4667: 4665: 4662: 4660: 4657: 4655: 4654:DHA-clozapine 4652: 4650: 4647: 4645: 4642: 4640: 4637: 4635: 4631: 4628: 4627: 4624: 4621: 4618: 4614: 4611: 4609: 4606: 4604: 4601: 4599: 4596: 4593: 4589: 4586: 4584: 4581: 4579: 4576: 4573: 4569: 4566: 4564: 4561: 4559: 4556: 4554: 4550: 4547: 4546: 4544: 4540: 4534: 4531: 4529: 4526: 4524: 4520: 4517: 4516: 4514: 4510: 4504: 4501: 4499: 4496: 4494: 4491: 4489: 4486: 4484: 4481: 4479: 4476: 4474: 4471: 4469: 4466: 4464: 4461: 4459: 4456: 4454: 4451: 4449: 4446: 4444: 4440: 4437: 4436: 4433: 4430: 4428: 4422: 4420: 4414: 4412: 4409: 4407: 4401: 4399: 4396: 4394: 4391: 4389: 4386: 4384: 4381: 4379: 4375: 4372: 4371: 4368: 4365: 4363: 4360: 4358: 4355: 4353: 4352:Dihydrexidine 4350: 4348: 4345: 4343: 4340: 4338: 4334: 4331: 4330: 4327: 4324: 4322: 4319: 4317: 4314: 4312: 4309: 4307: 4304: 4302: 4299: 4297: 4293: 4290: 4289: 4286: 4283: 4281: 4278: 4276: 4273: 4271: 4268: 4266: 4263: 4261: 4258: 4256: 4253: 4251: 4248: 4246: 4242: 4239: 4238: 4236: 4232: 4229: 4227: 4219: 4215: 4212: 4205: 4200: 4198: 4193: 4191: 4186: 4185: 4182: 4170: 4167: 4165: 4162: 4160: 4157: 4154: 4153: 4150: 4140: 4137: 4134: 4130: 4126: 4123: 4122: 4119: 4116: 4111: 4105: 4104: 4102: 4100: 4096: 4089: 4085: 4081: 4080:Bungarotoxins 4078: 4075: 4074: 4070: 4066: 4062: 4058: 4054: 4051: 4050:inactivators: 4046: 4040: 4039: 4035: 4031: 4027: 4023: 4020: 4019:inactivators: 4015: 4009: 4008: 4006: 4004: 4000: 3997: 3993: 3987: 3983: 3973: 3970: 3967: 3966: 3964: 3959: 3953: 3947: 3944: 3941: 3940: 3937: 3934: 3932: 3929: 3926: 3925: 3923: 3918: 3912: 3909: 3905: 3899: 3895: 3884: 3882: 3881:ZINC-12613047 3879: 3877: 3874: 3872: 3869: 3867: 3864: 3862: 3859: 3857: 3854: 3852: 3849: 3847: 3844: 3842: 3839: 3836: 3835: 3833: 3828: 3822: 3816: 3813: 3811: 3808: 3806: 3803: 3801: 3798: 3796: 3792: 3789: 3788: 3785: 3782: 3780: 3777: 3775: 3772: 3770: 3767: 3765: 3762: 3760: 3757: 3755: 3752: 3750: 3747: 3745: 3742: 3740: 3737: 3735: 3732: 3730: 3727: 3725: 3724:Lactucopicrin 3722: 3720: 3717: 3715: 3712: 3710: 3707: 3705: 3702: 3700: 3697: 3695: 3692: 3690: 3687: 3685: 3682: 3680: 3677: 3675: 3672: 3670: 3667: 3665: 3662: 3660: 3657: 3655: 3652: 3650: 3647: 3644: 3643: 3640: 3637: 3634: 3633: 3628: 3625: 3622: 3618: 3614: 3610: 3606: 3603: 3601: 3597: 3594: 3592: 3589: 3587: 3584: 3582: 3579: 3577: 3574: 3572: 3569: 3567: 3564: 3562: 3559: 3557: 3556:Trichloronate 3554: 3552: 3549: 3547: 3544: 3542: 3539: 3537: 3534: 3532: 3529: 3527: 3524: 3522: 3519: 3517: 3514: 3512: 3509: 3507: 3504: 3502: 3499: 3497: 3494: 3492: 3489: 3487: 3484: 3482: 3479: 3477: 3474: 3472: 3469: 3467: 3464: 3462: 3459: 3457: 3454: 3452: 3449: 3447: 3444: 3442: 3439: 3437: 3434: 3432: 3429: 3427: 3424: 3422: 3419: 3417: 3414: 3412: 3409: 3407: 3404: 3402: 3399: 3397: 3394: 3392: 3389: 3387: 3384: 3382: 3379: 3377: 3374: 3372: 3369: 3367: 3364: 3362: 3359: 3357: 3354: 3352: 3349: 3347: 3344: 3342: 3339: 3337: 3334: 3332: 3331:Monocrotophos 3329: 3327: 3324: 3322: 3319: 3317: 3314: 3312: 3309: 3307: 3304: 3302: 3299: 3297: 3296:Methamidophos 3294: 3292: 3289: 3287: 3284: 3282: 3279: 3277: 3274: 3272: 3269: 3267: 3264: 3262: 3259: 3257: 3254: 3252: 3249: 3247: 3244: 3242: 3239: 3237: 3234: 3232: 3229: 3227: 3224: 3222: 3219: 3217: 3214: 3212: 3209: 3207: 3204: 3202: 3199: 3197: 3194: 3192: 3189: 3187: 3184: 3182: 3179: 3177: 3174: 3172: 3171:Echothiophate 3169: 3167: 3164: 3162: 3159: 3157: 3154: 3152: 3149: 3147: 3144: 3142: 3139: 3137: 3134: 3132: 3129: 3127: 3124: 3122: 3119: 3117: 3114: 3112: 3109: 3107: 3104: 3102: 3099: 3097: 3094: 3092: 3089: 3087: 3084: 3082: 3079: 3077: 3074: 3072: 3069: 3067: 3064: 3062: 3059: 3057: 3054: 3052: 3049: 3047: 3044: 3042: 3039: 3037: 3034: 3032: 3029: 3027: 3024: 3022: 3019: 3017: 3014: 3012: 3009: 3007: 3004: 3002: 2999: 2997: 2994: 2992: 2989: 2987: 2984: 2982: 2979: 2977: 2973: 2972:Irreversible: 2970: 2969: 2966: 2963: 2961: 2958: 2956: 2953: 2951: 2948: 2946: 2943: 2941: 2938: 2936: 2933: 2931: 2928: 2926: 2923: 2921: 2918: 2916: 2913: 2911: 2908: 2906: 2903: 2901: 2898: 2896: 2893: 2891: 2888: 2886: 2883: 2881: 2878: 2876: 2873: 2871: 2868: 2866: 2863: 2861: 2858: 2856: 2853: 2851: 2847: 2844: 2842: 2839: 2837: 2836:Quilostigmine 2834: 2832: 2829: 2827: 2826:Physostigmine 2824: 2822: 2819: 2817: 2814: 2811: 2809: 2806: 2804: 2801: 2799: 2796:; Stigmines: 2795: 2792: 2790: 2787: 2785: 2782: 2780: 2777: 2775: 2772: 2770: 2767: 2765: 2762: 2760: 2757: 2755: 2752: 2750: 2747: 2745: 2742: 2740: 2737: 2735: 2732: 2730: 2727: 2725: 2722: 2720: 2717: 2715: 2712: 2710: 2707: 2705: 2702: 2700: 2697: 2695: 2694:Chloropropham 2692: 2690: 2687: 2685: 2682: 2680: 2677: 2675: 2672: 2670: 2667: 2665: 2662: 2660: 2657: 2655: 2652: 2650: 2647: 2645: 2641: 2638: 2636: 2632: 2631: 2629: 2624: 2618: 2612: 2609: 2607: 2604: 2602: 2599: 2597: 2594: 2592: 2589: 2587: 2584: 2582: 2579: 2577: 2574: 2572: 2569: 2567: 2564: 2562: 2559: 2557: 2554: 2551: 2550: 2548: 2543: 2537: 2534: 2530: 2524: 2520: 2516: 2513: 2509: 2506: 2505:Acetylcholine 2499: 2494: 2492: 2487: 2485: 2480: 2479: 2476: 2464: 2461: 2459: 2456: 2454: 2451: 2447: 2444: 2442: 2439: 2438: 2437: 2436: 2428: 2424: 2421: 2419: 2416: 2414: 2411: 2409: 2406: 2404: 2401: 2400: 2399: 2398: 2394: 2393: 2391: 2389: 2385: 2379: 2376: 2374: 2371: 2369: 2366: 2362: 2359: 2357: 2354: 2352: 2349: 2348: 2347: 2344: 2343: 2340: 2337: 2335: 2332: 2329: 2328: 2326: 2323: 2316: 2312: 2302: 2299: 2297: 2294: 2292: 2289: 2287: 2284: 2282: 2279: 2277: 2274: 2272: 2269: 2267: 2264: 2262: 2261:Isometheptene 2259: 2257: 2254: 2252: 2249: 2247: 2244: 2242: 2239: 2237: 2234: 2232: 2229: 2227: 2224: 2222: 2219: 2218: 2216: 2212: 2204: 2201: 2200: 2199: 2198: 2190: 2186: 2183: 2181: 2178: 2177: 2176: 2175: 2167: 2166: 2164: 2162: 2156: 2150: 2147: 2145: 2142: 2140: 2137: 2136: 2134: 2132: 2126: 2116: 2115:Tridihexethyl 2113: 2111: 2108: 2106: 2103: 2101: 2100:Propantheline 2098: 2096: 2093: 2091: 2088: 2086: 2083: 2081: 2078: 2076: 2073: 2071: 2068: 2066: 2065:Methantheline 2063: 2061: 2058: 2056: 2053: 2051: 2048: 2046: 2043: 2041: 2040:Fenpiverinium 2038: 2036: 2033: 2031: 2028: 2026: 2023: 2022: 2020: 2016: 2010: 2004: 2001: 1999: 1996: 1994: 1991: 1989: 1986: 1984: 1981: 1979: 1976: 1974: 1971: 1969: 1968:Dicycloverine 1966: 1964: 1961: 1960: 1958: 1952: 1949: 1947: 1943: 1940: 1938: 1928: 1923: 1919: 1911: 1906: 1904: 1899: 1897: 1892: 1891: 1888: 1882: 1878: 1877: 1872: 1870: 1867: 1863: 1859: 1855: 1854: 1850: 1841: 1835: 1832: 1827: 1823: 1819: 1815: 1811: 1807: 1803: 1799: 1792: 1789: 1784: 1780: 1775: 1770: 1766: 1762: 1758: 1754: 1750: 1743: 1740: 1735: 1731: 1727: 1723: 1716: 1713: 1708: 1704: 1700: 1696: 1692: 1688: 1684: 1680: 1673: 1670: 1665: 1661: 1656: 1651: 1647: 1643: 1639: 1635: 1631: 1624: 1621: 1616: 1612: 1605: 1598: 1595: 1590: 1586: 1581: 1576: 1571: 1566: 1562: 1558: 1554: 1547: 1544: 1539: 1535: 1530: 1525: 1521: 1517: 1513: 1506: 1503: 1498: 1494: 1487: 1484: 1479: 1475: 1471: 1467: 1460: 1457: 1452: 1448: 1444: 1440: 1432: 1429: 1424: 1420: 1415: 1410: 1405: 1400: 1396: 1392: 1388: 1381: 1379: 1377: 1375: 1373: 1371: 1367: 1362: 1356: 1352: 1351: 1343: 1341: 1339: 1335: 1330: 1324: 1320: 1319: 1311: 1309: 1305: 1300: 1296: 1291: 1286: 1282: 1278: 1274: 1267: 1264: 1259: 1255: 1250: 1245: 1241: 1237: 1233: 1226: 1223: 1218: 1212: 1208: 1201: 1198: 1182: 1175: 1169: 1166: 1159: 1157: 1156: 1152: 1148: 1144: 1140: 1136: 1132: 1128: 1124: 1120: 1116: 1112: 1108: 1104: 1100: 1096: 1091: 1085: 1079: 1074: 1066: 1061: 1059: 1057: 1050: 1048: 1046: 1043:, as well as 1042: 1038: 1034: 1029: 1027: 1023: 1019: 1015: 1014:acetylcholine 1006: 999: 997: 995: 986: 984: 982: 973: 971: 967: 961: 959: 955: 952: 940: 938: 936: 932: 928: 923: 913: 909: 901: 897: 893: 889: 883: 881: 877: 873: 869: 861: 859: 855: 853: 849: 847: 843: 839: 835: 831: 823: 821: 819: 815: 811: 807: 803: 798: 795: 793: 785: 783: 780: 775: 769: 766: 763: 761:regurgitation 760: 758: 755: 753: 750: 748: 745: 742: 739: 738: 737: 731: 726: 719: 717: 715: 711: 707: 703: 700: 692: 688: 687:gastrokinetic 684: 680: 677: 673: 670:; brand name 669: 665: 655: 648: 642: 633: 627: 622: 617: 613: 606: 596: 591: 587: 580: 573: 569:as HCl: 568: 565: 561: 560: 558: 555: 550: 543: 541: 537: 510: 508: 504: 499: 495: 491: 488: 486: 484:ECHA InfoCard 480: 472: 468: 467:DTXSID7048320 464: 463: 461: 452: 448: 441: 440:ChEMBL2107457 437: 436: 434: 432: 428: 421: 417: 416: 414: 412: 408: 401: 397:as HCl:  396: 393: 389: 388: 386: 384: 380: 373: 369:as HCl:  368: 365: 361: 360: 358: 356: 352: 345: 341: 340: 338: 336: 332: 325: 321:as HCl:  320: 317: 313: 312: 310: 308: 304: 297: 293: 292: 290: 283: 279: 272: 268:as HCl:  267: 264: 260: 259: 257: 255: 251: 243: 239: 235: 228: 223: 219: 215: 212: 210: 206: 203:5.7±0.3 hours 202: 200: 193: 189: 186:), primarily 185: 181: 177: 175: 171: 167: 165: 161: 157: 150: 148: 144: 140: 136: 129: 128: 126: 124: 120: 115: 107: 102: 99: 98: 96: 94: 90: 87: 84: 82: 76: 72: 68: 66: 62: 58: 54: 52: 48: 45:Clinical data 43: 39: 34: 30: 25: 6220: 6211: 6202: 6193: 6184: 6175: 6164: 6163: 6116:Stepholidine 6111:Spiroxatrine 6101:Seridopidine 6096:SB-277,011-A 6016:Fenfluramine 5976:Bromerguride 5956: 5950:Trimipramine 5945:Propiomazine 5925: 5904:Promethazine 5899:Metopimazine 5888: 5829: 5748:Paliperidone 5693:Fluperlapine 5683:Elopiprazole 5648:Clocapramine 5638:Carpipramine 5613: 5567:Thioridazine 5527:Prothipendyl 5487:Perphenazine 5447:Mesoridazine 5422:Homopipramol 5412:Fluspirilene 5402:Fluphenazine 5357:Clothixamide 5352:Clopenthixol 5327:Chloracizine 5322:Butaperazine 5292:Acepromazine 5287: 5247:Salvinorin A 5057: 5051:Norclozapine 5046:Lumateperone 5006:Aripiprazole 4996: 4936: 4905: 4859:Chanoclavine 4844: 4813: 4792: 4725: 4689:Paliperidone 4669:Norclozapine 4659:Fluperlapine 4629: 4603:Thioridazine 4588:Perphenazine 4578:Fluphenazine 4548: 4518: 4493:Stepholidine 4438: 4373: 4332: 4291: 4241:Benzazepines 4240: 4124: 4118:α-Latrotoxin 4106: 4076: 4041: 4010: 3968: 3942: 3927: 3871:Rivastigmine 3837: 3791:Reactivators 3764:Ungiminorine 3719:Kobophenol A 3684:Coronaridine 3674:Bulbocapnine 3669:Arisugacin A 3645: 3630: 3516:Tebupirimfos 3396:Phosphamidon 3301:Methidathion 3206:Fenitrothion 3031:Chlorpyrifos 2971: 2914: 2846:Terestigmine 2841:Rivastigmine 2803:Eptastigmine 2754:Phenmedipham 2724:Formparanate 2709:Ethiofencarb 2642:Carbamates: 2639: 2633: 2552: 2429: 2395: 2345: 2330: 2236:Diisopromine 2191: 2168: 2075:Oxyphenonium 2055:Isopropamide 1993:Piperidolate 1978:Dihexyverine 1874: 1861: 1834: 1801: 1798:Pharmacology 1797: 1791: 1756: 1752: 1742: 1725: 1721: 1715: 1682: 1678: 1672: 1637: 1633: 1623: 1617:(4): 207–10. 1614: 1610: 1597: 1560: 1556: 1546: 1519: 1515: 1505: 1496: 1492: 1486: 1469: 1465: 1459: 1442: 1438: 1431: 1394: 1390: 1349: 1317: 1280: 1276: 1266: 1239: 1235: 1225: 1206: 1200: 1188:. Retrieved 1181:the original 1168: 1154: 1150: 1146: 1138: 1110: 1099:Itoprid PMCS 1098: 1072: 1070: 1054: 1051:Interactions 1037:somatostatin 1030: 1011: 990: 974: 962: 944: 941:Pharmacology 924: 884: 865: 856: 850: 846:gynecomastia 842:galactorrhea 834:constipation 827: 799: 796: 789: 776: 773: 735: 720:Medical uses 709: 671: 663: 662: 651:   645:   324:DBSALT002665 241: 217: 196:Elimination 187: 123:Legal status 117:Legal status 6177:Adrenergics 6081:Pridopidine 6066:Nafadotride 6051:Metergoline 5966:Alpiropride 5914:Trazpiroben 5884:Hydroxyzine 5879:Eticlopride 5874:Domperidone 5844:Alimemazine 5818:Ziprasidone 5813:Zicronapine 5808:Veralipride 5793:Tefludazine 5783:Risperidone 5778:Remoxipride 5763:Pipotiazine 5753:Perospirone 5742:+fluoxetine 5733:Ocaperidone 5728:Mosapramine 5713:Mazapertine 5703:Iloperidone 5698:Gevotroline 5688:Flumezapine 5668:Cyamemazine 5653:Clorotepine 5633:Blonanserin 5618:Amisulpride 5572:Thiothixene 5507:Pipamperone 5472:Perathiepin 5467:Penfluridol 5462:Nemonapride 5417:Haloperidol 5396:+melitracen 5362:Clopimozide 5312:Bromperidol 5281:Antagonists 5272:WAY-100,635 5217:Quinelorane 5212:Quinagolide 5192:Pramipexole 5157:Pardoprunox 5142:Mesulergine 5132:Flibanserin 5122:Dizocilpine 5102:Armodafinil 5092:Apomorphine 5036:Cariprazine 5010:+sertraline 4951:Etilevodopa 4874:Ergocornine 4869:Epicriptine 4854:Cabergoline 4807:Rimantadine 4793:Adamantanes 4714:Ziprasidone 4709:Zicronapine 4704:Tefludazine 4699:Risperidone 4683:+fluoxetine 4664:Iloperidone 4639:Clorotepine 4608:Thiothixene 4598:Pifluthixol 4572:+melitracen 4542:Antagonists 4448:Apomorphine 4393:Etilevodopa 4367:Doxanthrine 4357:Dinapsoline 4296:Cabergoline 3969:Inhibitors: 3946:Coluracetam 3928:Inhibitors: 3898:Transporter 3838:Inhibitors: 3810:Pralidoxime 3704:Cyclanoline 3654:α-Viniferin 3551:Trichlorfon 3316:Metrifonate 3231:Fosthiazate 3216:Fluorotabun 3091:Dicrotophos 3046:Crotylsarin 2890:Huperzine A 2885:Galantamine 2880:Edrophonium 2813:Neostigmine 2808:Ganstigmine 2774:Propamocarb 2719:Formetanate 2704:Ethienocarb 2684:Carbosulfan 2674:Carbetamide 2669:Carbendazim 2640:Reversible: 2553:Inhibitors: 2441:Cinitapride 2418:Domperidone 2388:Propulsives 2351:Scopolamine 2339:Hyoscyamine 2296:Trepibutone 2291:Tiropramide 2256:Idanpramine 2185:Cilansetron 2174:antagonists 2139:Drotaverine 2085:Pipenzolate 2080:Penthienate 2060:Mepenzolate 2050:Hexocyclium 2003:Trimebutine 1956:amino group 1876:NCT00272103 1499:(1): 17–20. 1026:peristalsis 927:QT interval 880:arrhythmias 876:QT interval 547: g·mol 490:100.222.888 420:CHEBI:94809 271:122892-31-3 263:122898-67-3 225:Identifiers 158:= 35±5 min) 51:Trade names 6272:Benzamides 6261:Categories 6086:Raclopride 6076:PNU-99,194 6071:Nuciferine 6011:Fananserin 6006:Fallypride 5935:Nefazodone 5864:Clebopride 5859:Bromopride 5849:Alizapride 5803:Tiospirone 5798:Tenilapine 5788:Sertindole 5773:Quetiapine 5768:Piquindone 5738:Olanzapine 5708:Lurasidone 5678:Dixyrazine 5643:Cinuperone 5602:Zetidoline 5577:Timiperone 5552:Teflutixol 5547:Sultopride 5387:Fluotracen 5382:Flucindole 5377:Fluanisone 5372:Fluacizine 5367:Droperidol 5347:Ciclindole 5317:Butaclamol 5307:Benperidol 5267:Umespirone 5262:Talipexole 5257:Sumanirole 5252:SKF-83,959 5237:Ropinirole 5222:Quinpirole 5177:PF-592,379 5172:PF-219,061 5167:PD-168,077 5162:PD-128,907 5127:Esketamine 5117:CP-226,269 5112:Captodiame 5097:Arketamine 5021:Bifeprunox 4985:Melevodopa 4946:Dopexamine 4925:Dinoxyline 4879:Lergotrile 4833:Rotigotine 4797:Amantadine 4694:Quetiapine 4679:Olanzapine 4644:Clotiapine 4553:Butaclamol 4488:SKF-89,626 4483:SKF-89,145 4478:Rotigotine 4468:PF 6669571 4463:PF-6649751 4458:Nuciferine 4411:Melevodopa 4388:Dopexamine 4362:Dinoxyline 4301:CY-208,243 4285:Zelandopam 4275:SKF-83,959 4270:SKF-82,958 4265:SKF-81,297 4260:SKF-77,434 4255:SKF-38,393 4250:Fenoldopam 4214:modulators 4133:versutoxin 4129:robustoxin 4003:Inhibitors 3992:modulators 3943:Enhancers: 3904:modulators 3861:Ladostigil 3851:Conodurine 3846:Affinisine 3759:Ungeremine 3734:Phosacetim 3694:Corynoline 3689:Corydaline 3679:Conodurine 3664:Affinisine 3600:Demecarium 3598:; Others: 3511:Tabun (GA) 3501:Soman (GD) 3491:Sarin (GB) 3411:Profenofos 3271:Isoxathion 3256:Guanitoxin 3226:Formothion 3201:Fenamiphos 3131:Disulfoton 3126:Dioxathion 3116:Dimethoate 3086:Dichlorvos 2920:Ladostigil 2910:Ipidacrine 2855:Ambenonium 2850:Acotiamide 2848:; Others: 2821:Phenserine 2798:Distigmine 2789:Thiodicarb 2764:Pirimicarb 2729:Methiocarb 2714:Fenobucarb 2689:Chlorbufam 2679:Carbofuran 2654:Bendiocarb 2635:Inhibitors 2529:modulators 2515:modulators 2508:metabolism 2458:Ilebopride 2453:Acotiamide 2413:Clebopride 2408:Bromopride 2403:Alizapride 2315:Belladonna 2286:Simeticone 2251:Fenpiprane 2246:Fenoverine 2226:Caroverine 2149:Papaverine 2144:Moxaverine 2131:inhibitors 2110:Timepidium 2035:Diphemanil 2013:Quaternary 1998:Rociverine 1983:Mebeverine 1973:Difemerine 1933:functional 1916:Drugs for 1858:"Itopride" 1190:9 December 1160:References 954:antagonist 912:benzamides 852:Leukopenia 810:hemorrhage 802:benzamides 702:antagonist 676:prokinetic 552:3D model ( 540:Molar mass 372:2H9NV66W0I 364:81BMQ80QRL 335:ChemSpider 254:CAS Number 234:IUPAC name 190:-oxidation 174:Metabolism 6165:See also: 6146:Yohimbine 6126:Terguride 6091:Sarizotan 6036:L-745,870 6031:L-741,626 5986:Buspirone 5940:Opipramol 5930:Amoxapine 5723:Molindone 5718:Melperone 5663:Clozapine 5623:Asenapine 5542:Sulpiride 5522:Promazine 5512:Preclamol 5427:Lenperone 5302:Azaperone 5242:Roxindole 5232:Ro10-5824 5207:Pukateine 5197:Preclamol 5187:Piribedil 5147:Modafinil 5087:Aplindore 5082:Adrafinil 4980:-Tyrosine 4956:Ibopamine 4899:Terguride 4894:Pergolide 4845:Ergolines 4828:8-OH-PBZI 4823:7-OH-DPAT 4818:5-OH-DPAT 4802:Memantine 4760:SCH-23390 4755:Perlapine 4730:Berupipam 4649:Clozapine 4634:Asenapine 4533:Mevidalen 4498:Tavapadon 4427:-Tyrosine 4398:Ibopamine 4326:Terguride 4321:Pergolide 4292:Ergolines 4115:agonists: 4099:Enhancers 3972:Vesamicol 3856:Cymserine 3805:Obidoxime 3800:Methoxime 3714:Harmaline 3709:Cymserine 3699:Crimidine 3646:Unsorted: 3541:Triazofos 3481:Ro 3-0433 3476:Ro 3-0422 3471:Ro 3-0419 3466:Ro 3-0417 3461:Ro 3-0412 3456:Ro 3-0411 3451:Ro 3-0397 3446:Ro 3-0352 3441:Ro 3-0351 3436:Ro 3-0347 3431:Ro 3-0346 3426:Ro 3-0340 3416:Prothoate 3386:Phosfolan 3381:Phosalone 3366:Parathion 3351:Omethoate 3321:Mevinphos 3286:Malathion 3276:Leptophos 3181:Endothion 3061:Demephion 3051:Cyanophos 3041:Coumaphos 3011:Cadusafos 3006:Bensulide 3001:BAY-29952 2965:Zanapezil 2925:Minaprine 2905:Huprine Y 2900:Huprine X 2895:Huprine W 2865:Donepezil 2794:Thiofanox 2769:Promecarb 2759:Pinmicarb 2739:Metolcarb 2699:Dimetilan 2659:Bufencarb 2649:Aminocarb 2601:CM-54,903 2512:transport 2463:Mosapride 2446:Cisapride 2281:Proxazole 2203:Mosapride 2180:Alosetron 2158:Acting on 2105:Tiemonium 2095:Prifinium 2070:Otilonium 2025:Benzilone 2018:compounds 1963:Camylofin 1937:disorders 1930:Drugs for 981:prolactin 935:mosapride 931:cisapride 896:mosapride 892:cisapride 872:cisapride 870:group as 868:benzamide 806:lactation 757:heartburn 741:dyspepsia 679:benzamide 209:Excretion 198:half-life 79:Routes of 65:Drugs.com 6251:Medicine 6136:Tiapride 6046:LEK-8829 5971:Azapride 5889:Itopride 5823:Zotepine 5502:Pimozide 5477:Perazine 5452:Moperone 5442:Loxapine 5152:OSU-6162 5137:Ketamine 5067:A-412997 4915:Ciladopa 4910:2-OH-NPA 4884:Lisuride 4786:Agonists 4750:Odapipam 4735:Ecopipam 4719:Zotepine 4583:Loxapine 4316:Lisuride 4311:LEK-8829 4280:Trepipam 4245:6-Br-APB 4234:Agonists 4155:See also 4139:Crotoxin 3841:Affinine 3774:BW284C51 3729:Lycorine 3659:Affinine 3649:α-Pinene 3627:Onchidal 3546:Tribufos 3526:Terbufos 3496:Schradan 3361:Paraoxon 3281:Malaoxon 3211:Fenthion 3196:Ethoprop 3081:Diazinon 3076:Dialifor 2981:Acephate 2915:Itopride 2860:Caffeine 2784:Propoxur 2734:Methomyl 2664:Carbaryl 2644:Aldicarb 2435:agonists 2334:Atropine 2221:Alverine 2197:agonists 2030:Bevonium 2015:ammonium 1954:Tertiary 1826:22219251 1818:16717477 1783:23960836 1734:11127807 1707:25760696 1699:18179609 1664:18581598 1589:16015691 1538:16495395 1478:15305632 1451:18019739 1423:23326147 1299:16495395 983:levels. 951:receptor 900:myocytes 838:headache 818:dopamine 764:bloating 752:anorexia 710:Itopride 699:receptor 683:dopamine 664:Itopride 654:(verify) 307:DrugBank 93:ATC code 86:By mouth 21:Itopride 6001:F-15063 5839:AS-8112 5628:BL-1020 5457:Naranol 5227:RDS-127 5077:ABT-724 5072:ABT-670 5041:F-15063 4990:XP21279 4443:A-68930 4432:XP21279 4378:BCO-001 4342:A-86929 4337:A-77636 4125:Others: 4077:Others: 4013:SNAP-25 3986:Release 3876:Tacrine 3784:3152 CT 3749:Taspine 3521:Temefos 3421:R-16661 3391:Phosmet 3376:Phorate 3326:Mipafox 3291:Mazidox 3221:Fonofos 3166:EA-4352 3161:EA-3148 3156:EA-2613 3151:EA-2192 3146:EA-2098 3141:EA-2054 3136:EA-2012 3111:Dimefox 3066:Demeton 2960:Tacrine 2955:TL-1238 2875:EA-4056 2870:EA-3990 2779:Propham 2744:Miotine 2090:Poldine 1774:3744972 1655:2615341 1580:4615444 1414:3544044 1258:8835639 1147:Itogard 1073:Ganaton 1033:motilin 674:) is a 672:Ganaton 545:358.438 507:Formula 316:DB04924 282:PubChem 220:-oxide) 109:) 103: ( 101:A03FA07 55:Ganaton 6237:Portal 6141:UH-232 6121:SV-293 5957:Others 5107:BP-897 5058:Others 4838:UH-232 4726:Others 4439:Others 3486:Ronnel 3401:Phoxim 3191:Ethion 2986:Armine 2950:TL-599 2945:T-1194 2940:T-1152 2935:T-1123 2749:Oxamyl 2523:Enzyme 1935:bowel 1824:  1816:  1781:  1771:  1732:  1705:  1697:  1662:  1652:  1587:  1577:  1536:  1476:  1449:  1421:  1411:  1357:  1325:  1297:  1256:  1213:  1139:Prokit 1137:) and 1111:Itomed 844:, and 586:SMILES 431:ChEMBL 400:D02729 392:D08094 151:~60% ( 5961:3-PPP 5062:3-PPP 4778:-like 4226:-like 3957:VAChT 3779:TMTFA 3341:Naled 3246:GT-45 3236:GD-42 2586:AF64A 2214:Other 1822:S2CID 1703:S2CID 1607:(PDF) 1184:(PDF) 1177:(PDF) 1155:Zirid 1151:Dagla 1067:Names 808:, GI 612:InChI 554:JSmol 411:ChEBI 214:Renal 5996:EEDQ 4740:EEDQ 4528:DPTQ 4523:DETQ 4512:PAMs 4109:LPHN 4044:VAMP 3826:BChE 3336:MSPI 2622:AChE 2596:BETA 2591:B115 2541:ChAT 2510:and 2431:5-HT 2193:5-HT 2170:5-HT 1814:PMID 1779:PMID 1730:PMID 1695:PMID 1660:PMID 1585:PMID 1534:PMID 1474:PMID 1447:PMID 1419:PMID 1355:ISBN 1323:ISBN 1295:PMID 1254:PMID 1211:ISBN 1192:2015 1020:and 956:and 905:5-HT 894:and 830:rash 704:and 383:KEGG 355:UNII 344:3660 296:3792 184:FMO3 182:and 180:FMO1 141:data 61:AHFS 4889:LSD 3916:CHT 3186:EPN 1922:A03 1840:"Z" 1806:doi 1769:PMC 1761:doi 1726:106 1687:doi 1650:PMC 1642:doi 1575:PMC 1565:doi 1524:doi 1520:354 1409:PMC 1399:doi 1285:doi 1281:354 1244:doi 1109:), 1097:), 1093:), 933:or 792:OTC 668:INN 456:EPA 286:CID 168:96% 155:max 106:WHO 6263:: 5959:: 5928:: 5832:: 5616:: 5290:: 5060:: 4999:: 4939:: 4908:: 4847:: 4816:: 4795:: 4728:: 4632:: 4551:: 4521:: 4441:: 4376:: 4335:: 4294:: 4243:: 4131:, 4086:, 4067:, 4063:, 4059:, 4032:, 4028:, 3793:: 3619:, 3615:, 3611:, 3596:VX 3591:VR 3586:VS 3581:VP 3576:VM 3571:VG 3566:VE 3251:GV 3241:GH 1860:. 1820:. 1812:. 1802:77 1800:. 1777:. 1767:. 1757:21 1755:. 1751:. 1724:. 1701:. 1693:. 1683:20 1681:. 1658:. 1648:. 1638:49 1636:. 1632:. 1615:12 1613:. 1609:. 1583:. 1573:. 1561:11 1559:. 1555:. 1532:. 1518:. 1514:. 1497:59 1495:. 1470:50 1468:. 1443:54 1441:. 1417:. 1407:. 1395:18 1393:. 1389:. 1369:^ 1337:^ 1307:^ 1293:. 1279:. 1275:. 1252:. 1240:71 1238:. 1234:. 1143:PL 1135:UZ 1133:, 1131:UA 1129:, 1127:RU 1125:, 1123:MD 1121:, 1119:KZ 1117:, 1115:KG 1107:SK 1105:, 1103:CZ 1090:RU 1087:, 1084:CZ 1081:, 1078:JP 1035:, 972:. 960:. 848:. 836:, 804:; 716:. 708:. 521:26 515:20 6239:: 5744:) 5740:( 5588:) 5584:( 5493:) 5489:( 5398:) 5394:( 5012:) 5008:( 4978:L 4970:L 4962:L 4776:2 4774:D 4685:) 4681:( 4619:) 4615:( 4594:) 4590:( 4574:) 4570:( 4425:L 4417:L 4404:L 4224:1 4222:D 4203:e 4196:t 4189:v 4135:) 4090:) 4082:( 4071:) 4069:G 4065:F 4061:D 4057:B 4055:( 4036:) 4034:E 4030:C 4026:A 4024:( 3994:) 3990:( 3906:) 3902:( 3635:) 3629:( 3623:) 3621:4 3617:3 3613:2 3609:1 3607:( 2637:: 2531:) 2527:( 2497:e 2490:t 2483:v 2433:4 2324:) 2320:( 2195:4 2172:3 1924:) 1920:( 1909:e 1902:t 1895:v 1842:. 1828:. 1808:: 1785:. 1763:: 1736:. 1709:. 1689:: 1666:. 1644:: 1591:. 1567:: 1540:. 1526:: 1480:. 1453:. 1425:. 1401:: 1363:. 1331:. 1301:. 1287:: 1260:. 1246:: 1219:. 1194:. 1141:( 1113:( 1101:( 1075:( 977:2 949:2 947:D 920:4 916:4 907:4 732:. 697:2 695:D 666:( 556:) 533:4 530:O 527:2 524:N 518:H 512:C 458:) 454:( 242:N 218:N 188:N 153:T 63:/

Index



Trade names
AHFS
Drugs.com
International Drug Names
Routes of
administration

By mouth
ATC code
A03FA07
WHO
Legal status
Pharmacokinetic
Bioavailability
Tmax
Protein binding
Metabolism
FMO1
FMO3
Elimination half-life
Excretion
Renal
IUPAC name
CAS Number
122898-67-3
122892-31-3
PubChem
3792
DrugBank
DB04924

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