Knowledge (XXG)

Indy (gene)

Source šŸ“

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Rogina B, Reenan RA, Nilsen SP, Helfand SL (15 December 2000). "Extended life-span conferred by cotransporter gene mutations in Drosophila".
527: 310: 117: 38: 210: 233:) modeled the effects on obesity and diabetes of caloric reduction in primates such as humans. A similar effect was seen with 336: 204:
of fruit flies in at least one set of experiments, but this result has been subject to controversy. Both Indy proteins are
440: 205: 520: 192: 223: 391:"The longevity gene mIndy (I'm Not Dead, Yet) affects blood pressure through sympathoadrenal mechanisms" 360:"The longevity gene mIndy (I'm Not Dead, Yet) affects blood pressure through sympathoadrenal mechanisms" 275: 556: 513: 422: 291: 497: 412: 402: 371: 283: 461: 201: 157: 78: 389:
Willmes DM, Daniels M, Kurzbach A, Lieske S, Bechmann N, Schumann T, et al. (2021).
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Willmes DM, Schumann T, Henke C, Kurzbach A, Luft F, Morawietz H, et al. (2018).
540: 441:"The longevity gene mammalian Indy (mINDY) is involved in blood pressure regulation" 246: 287: 167: 88: 407: 359: 133: 54: 426: 295: 229: 138: 59: 465: 234: 485: 493: 187: 200:. Mutant versions of this gene have doubled the average 501: 208:. Its name originates from a well-known comic line in 163: 153: 148: 132: 124: 112: 107: 102: 84: 74: 69: 53: 45: 33: 28: 23: 521: 364:Journal of the American College of Cardiology 8: 528: 514: 145: 66: 416: 406: 337:"Diet, diabetes, and a gene called mINDY" 258: 99: 20: 7: 482: 480: 309:Niku M, Taipale M (25 March 2003). 217:Reduced expression of this gene in 500:. You can help Knowledge (XXG) by 14: 484: 552:Monty Python and the Holy Grail 211:Monty Python and the Holy Grail 311:"Clever Drosophila gene names" 1: 547:Drosophila melanogaster genes 468:database of Drosophila genes. 376:10.1016/S0735-1097(18)32354-4 288:10.1126/science.290.5499.2137 237:(mIndy) knockouts of mice. 573: 479: 408:10.1172/jci.insight.136083 339:. Yale School of Medicine 206:sodium sulfate symporters 144: 65: 16:Gene found in fruit flies 472:INDY (Iā€™m Not Dead, Yet) 219:Drosophila melanogaster 193:Drosophila melanogaster 190:found in the fruit fly 118:Drosophila melanogaster 39:Drosophila melanogaster 280:2000Sci...290.2137R 317:on 3 February 2007 103:I'm not dead yet 2 509: 508: 274:(5499): 2137ā€“40. 177: 176: 173: 172: 98: 97: 94: 93: 564: 530: 523: 516: 488: 481: 449: 448: 437: 431: 430: 420: 410: 386: 380: 379: 355: 349: 348: 346: 344: 333: 327: 326: 324: 322: 313:. Archived from 306: 300: 299: 263: 232: 184:I'm not dead yet 146: 120: 100: 67: 41: 24:I'm not dead yet 21: 572: 571: 567: 566: 565: 563: 562: 561: 537: 536: 535: 534: 477: 458: 453: 452: 439: 438: 434: 388: 387: 383: 357: 356: 352: 342: 340: 335: 334: 330: 320: 318: 308: 307: 303: 265: 264: 260: 255: 243: 228: 196:, an important 116: 37: 17: 12: 11: 5: 570: 568: 560: 559: 554: 549: 539: 538: 533: 532: 525: 518: 510: 507: 506: 489: 475: 474: 469: 457: 456:External links 454: 451: 450: 445:Medical Xpress 432: 401:(2): e136083. 381: 370:(11S): A1813. 350: 328: 301: 257: 256: 254: 251: 250: 249: 242: 239: 198:model organism 175: 174: 171: 170: 165: 161: 160: 155: 151: 150: 142: 141: 136: 130: 129: 126: 122: 121: 114: 110: 109: 105: 104: 96: 95: 92: 91: 86: 82: 81: 76: 72: 71: 63: 62: 57: 51: 50: 47: 43: 42: 35: 31: 30: 26: 25: 15: 13: 10: 9: 6: 4: 3: 2: 569: 558: 555: 553: 550: 548: 545: 544: 542: 531: 526: 524: 519: 517: 512: 511: 505: 503: 499: 496:article is a 495: 490: 487: 483: 478: 473: 470: 467: 463: 460: 459: 455: 446: 442: 436: 433: 428: 424: 419: 414: 409: 404: 400: 396: 392: 385: 382: 377: 373: 369: 365: 361: 354: 351: 338: 332: 329: 316: 312: 305: 302: 297: 293: 289: 285: 281: 277: 273: 269: 262: 259: 252: 248: 245: 244: 240: 238: 236: 231: 226: 225: 220: 215: 213: 212: 207: 203: 199: 195: 194: 189: 185: 181: 169: 166: 162: 159: 156: 152: 147: 143: 140: 137: 135: 131: 127: 123: 119: 115: 111: 106: 101: 90: 87: 83: 80: 77: 73: 68: 64: 61: 58: 56: 52: 48: 44: 40: 36: 32: 27: 22: 19: 502:expanding it 491: 476: 444: 435: 398: 394: 384: 367: 363: 353: 341:. Retrieved 331: 319:. Retrieved 315:the original 304: 271: 267: 261: 247:Cell biology 222: 218: 216: 209: 191: 183: 182:, short for 179: 178: 18: 395:JCI Insight 321:15 February 158:Swiss-model 108:Identifiers 79:Swiss-model 29:Identifiers 557:Gene stubs 541:Categories 253:References 224:C. elegans 221:flies and 154:Structures 149:Search for 75:Structures 70:Search for 202:life span 427:33491666 296:11118146 241:See also 168:InterPro 113:Organism 89:InterPro 34:Organism 466:FlyBase 447:. 2021. 418:7934862 276:Bibcode 268:Science 235:SLC13A5 227:worms ( 186:, is a 164:Domains 134:UniProt 85:Domains 55:UniProt 425:  415:  343:25 May 294:  230:P32739 139:Q9VDQ0 128:Indy-2 125:Symbol 60:Q9VVT2 46:Symbol 492:This 498:stub 494:gene 462:Indy 423:PMID 345:2019 323:2007 292:PMID 188:gene 180:Indy 49:Indy 464:at 413:PMC 403:doi 372:doi 284:doi 272:290 543:: 443:. 421:. 411:. 397:. 393:. 368:71 366:. 362:. 290:. 282:. 270:. 214:. 529:e 522:t 515:v 504:. 429:. 405:: 399:6 378:. 374:: 347:. 325:. 298:. 286:: 278::

Index

Drosophila melanogaster
UniProt
Q9VVT2
Swiss-model
InterPro
Drosophila melanogaster
UniProt
Q9VDQ0
Swiss-model
InterPro
gene
Drosophila melanogaster
model organism
life span
sodium sulfate symporters
Monty Python and the Holy Grail
C. elegans
P32739
SLC13A5
Cell biology
Bibcode
2000Sci...290.2137R
doi
10.1126/science.290.5499.2137
PMID
11118146
"Clever Drosophila gene names"
the original
"Diet, diabetes, and a gene called mINDY"
"The longevity gene mIndy (I'm Not Dead, Yet) affects blood pressure through sympathoadrenal mechanisms"

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