Knowledge (XXG)

International Studies of Infarct Survival

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ISIS-3 (Third International Study of lnfarct Survival) Collaborative Group (1992), "ISIS-3: a randomised comparison of streptokinase vs tissue plasminogen activator vs anistreplase and of aspirin plus heparin vs aspirin alone among 41 299 cases of suspected acute myocardial infarction",
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ISIS-4 (Fourth International Study of Infarct Survival) Collaborative Group (1995), "ISIS-4: A randomised factorial trial assessing early oral captopril, oral mononitrate, and intravenous magnesium sulphate in 58 050 patients with suspected acute myocardial infarction",
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ISIS-2 (Second International Study of lnfarct Survival) Collaborative Group (1988), "Randomised Trial of Intravenous Streptokinase, Oral Aspirin, Both, or Neither Among 17 187 Cases of Suspected Acute Myocardial Infarction: ISIS-2",
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ISIS-1 (Second International Study of lnfarct Survival) Collaborative Group (1986), "Randomised trial of intravenous atenolol among 16027 cases of suspected acute myocardial infarction: ISIS-1",
449: 400: 351: 294: 469: 42:("heart attack"). More than 134,000 patients from over 20 countries took part in four large simple trials between 1981 and 1993, coordinated from 175: 474: 181: 244: 201:
Hennekens, Charles H. (1998), "Trials of Thrombolytic Therapy: the International Studies of Infarct Survival Experience",
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Hennekens, Charles H.; Skerrett, P.J. (2005). "International Studies of Infarct Survival (ISIS)".
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The Fourth International Study of Infarct Survival (ISIS-4) was a 2×2×2
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The Second International Study of Infarct Survival (ISIS-2) was a 2×2
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The Third International Study of Infarct Survival (ISIS-3) was a 3×2
43: 172:, an Italian group who conducted four similar large clinical trials 169: 54:
The First International Study of Infarct Survival (ISIS-1) was a
32: 160:. It recruited 58,050 patients and was completed in 1993. 128:. It recruited 41,299 patients and was completed in 1991. 89:. It recruited 17,187 patients and was completed in 1988. 65:. It recruited 16,027 patients and was completed in 1985. 8: 124:to no heparin. All patients were also given 448:: CS1 maint: numeric names: authors list ( 399:: CS1 maint: numeric names: authors list ( 350:: CS1 maint: numeric names: authors list ( 293:: CS1 maint: numeric names: authors list ( 21:International Studies of Infarct Survival 193: 441: 392: 343: 286: 470:Clinical trials related to cardiology 176:Thrombolysis In Myocardial Infarction 117:to each other, and also compared the 7: 203:Journal of Interventional Cardiology 215:10.1111/j.1540-8183.1998.tb00089.x 14: 182:Myocardial infarction management 140:placebo-controlled trial of the 16:Studies of heart attack survival 101:trial that compared the three 1: 429:10.1016/S0140-6736(95)90865-X 323:10.1016/S0140-6736(88)92833-4 274:10.1016/S0140-6736(86)91607-7 229:Encyclopedia of Biostatistics 142:angiotensin-converting enzyme 380:10.1016/0140-6736(92)91893-D 111:tissue plasminogen activator 77:placebo-controlled trial of 29:randomized controlled trials 237:10.1002/0470011815.b2a01031 491: 475:Interventional cardiology 56:placebo-controlled trial 35:for treating suspected 154:isosorbide mononitrate 40:myocardial infarction 158:magnesium sulphate 423:(8951): 669–682, 374:(8796): 753–770, 317:(8607): 349–360, 482: 454: 453: 447: 439: 411: 405: 404: 398: 390: 362: 356: 355: 349: 341: 305: 299: 298: 292: 284: 257: 251: 250: 224: 218: 217: 198: 490: 489: 485: 484: 483: 481: 480: 479: 460: 459: 458: 457: 440: 413: 412: 408: 391: 364: 363: 359: 342: 307: 306: 302: 285: 268:(8498): 57–66, 259: 258: 254: 247: 226: 225: 221: 200: 199: 195: 190: 166: 134: 95: 71: 52: 17: 12: 11: 5: 488: 486: 478: 477: 472: 462: 461: 456: 455: 406: 357: 300: 252: 245: 219: 192: 191: 189: 186: 185: 184: 179: 173: 165: 162: 133: 130: 94: 91: 70: 67: 51: 48: 15: 13: 10: 9: 6: 4: 3: 2: 487: 476: 473: 471: 468: 467: 465: 451: 445: 438: 434: 430: 426: 422: 418: 410: 407: 402: 396: 389: 385: 381: 377: 373: 369: 361: 358: 353: 347: 340: 336: 332: 328: 324: 320: 316: 312: 304: 301: 296: 290: 283: 279: 275: 271: 267: 263: 256: 253: 248: 242: 238: 234: 230: 223: 220: 216: 212: 208: 204: 197: 194: 187: 183: 180: 177: 174: 171: 168: 167: 163: 161: 159: 155: 151: 147: 146:ACE inhibitor 143: 139: 131: 129: 127: 123: 120: 119:anticoagulant 116: 112: 108: 107:streptokinase 104: 100: 92: 90: 88: 87:streptokinase 84: 80: 76: 68: 66: 64: 61: 57: 49: 47: 45: 41: 38: 34: 30: 26: 22: 420: 416: 409: 371: 367: 360: 314: 310: 303: 265: 261: 255: 228: 222: 206: 202: 196: 135: 115:anistreplase 103:thrombolytic 96: 83:thrombolytic 72: 60:beta-blocker 53: 27:) were four 24: 20: 18: 144:inhibitor ( 46:, England. 31:of several 464:Categories 417:The Lancet 368:The Lancet 311:The Lancet 262:The Lancet 246:047084907X 188:References 113:(tPA) and 150:captopril 138:factorial 99:factorial 75:factorial 444:citation 437:33961715 395:citation 346:citation 339:21071664 289:citation 164:See also 81:and the 63:atenolol 331:2899772 209:: 1–7, 126:aspirin 122:heparin 79:aspirin 58:of the 435:  388:560345 386:  337:  329:  282:708900 280:  243:  178:(TIMI) 132:ISIS-4 105:drugs 93:ISIS-3 69:ISIS-2 50:ISIS-1 44:Oxford 433:S2CID 384:S2CID 335:S2CID 278:S2CID 170:GISSI 156:and 85:drug 37:acute 33:drugs 450:link 401:link 352:link 327:PMID 295:link 241:ISBN 25:ISIS 19:The 425:doi 421:345 376:doi 372:339 319:doi 315:332 270:doi 266:328 233:doi 211:doi 466:: 446:}} 442:{{ 431:, 419:, 397:}} 393:{{ 382:, 370:, 348:}} 344:{{ 333:, 325:, 313:, 291:}} 287:{{ 276:, 264:, 239:. 231:. 207:11 205:, 152:, 148:) 109:, 452:) 427:: 403:) 378:: 354:) 321:: 297:) 272:: 249:. 235:: 213:: 23:(

Index

randomized controlled trials
drugs
acute
myocardial infarction
Oxford
placebo-controlled trial
beta-blocker
atenolol
factorial
aspirin
thrombolytic
streptokinase
factorial
thrombolytic
streptokinase
tissue plasminogen activator
anistreplase
anticoagulant
heparin
aspirin
factorial
angiotensin-converting enzyme
ACE inhibitor
captopril
isosorbide mononitrate
magnesium sulphate
GISSI
Thrombolysis In Myocardial Infarction
Myocardial infarction management
doi

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