Knowledge (XXG)

Isolation chip

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24:) is a method of culturing bacteria. Using regular methods, 99% of bacterial species are not able to be cultured as they do not grow in conditions made in a laboratory, a problem called the "Great Plate Count Anomaly". The ichip instead cultures bacterial species within its soil environment. The soil is diluted in molten agar and nutrients such that only a single cell, on average, grows in the ichip's small compartments or wells, hence the term "isolation". The chip is then enclosed in a semipermeable plastic membrane and buried back in the dirt to allow in nutrients not available in the lab. With this culturing method, about 50 to 60 percent of bacterial species are able to survive. Notably, the bacterial species 41:, was discovered using the ichip in 2015. In addition to antibiotics, it is argued that anti-cancer agents, anti-inflammatory and immunosuppressives (which have previously been discovered from bacteria) as well as potential energy sources could be discovered. The ichip was developed by the drug discovery company 35: 92: 42: 65: 120: 26: 114: 31: 34:
that has shown promise against many drug-resistant strains like
8: 66:"iChip: The future of antibiotic discovery" 45:, founded by Kim Lewis and Slava Epstein. 60: 58: 54: 7: 87: 85: 83: 14: 1: 30:, which makes the antibiotic 137: 43:NovoBiotic Pharmaceuticals 93:"The age of infection" 36:methicillin-resistant 38:Staphylococcus aureus 95:. foreignpolicy.com 27:Eleftheria terrae 128: 105: 104: 102: 100: 89: 78: 77: 75: 73: 62: 136: 135: 131: 130: 129: 127: 126: 125: 111: 110: 109: 108: 98: 96: 91: 90: 81: 71: 69: 64: 63: 56: 51: 12: 11: 5: 134: 132: 124: 123: 113: 112: 107: 106: 79: 53: 52: 50: 47: 18:Isolation chip 13: 10: 9: 6: 4: 3: 2: 133: 122: 119: 118: 116: 94: 88: 86: 84: 80: 67: 61: 59: 55: 48: 46: 44: 40: 39: 33: 29: 28: 23: 19: 97:. Retrieved 70:. Retrieved 68:. popsci.com 37: 25: 21: 17: 15: 32:teixobactin 49:References 99:2 October 72:3 October 121:Bacteria 115:Category 22:ichip 101:2015 74:2015 20:(or 16:The 117:: 82:^ 57:^ 103:. 76:.

Index

Eleftheria terrae
teixobactin
methicillin-resistant Staphylococcus aureus
NovoBiotic Pharmaceuticals


"iChip: The future of antibiotic discovery"



"The age of infection"
Category
Bacteria

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