250:
bacteria that make use of one carbon compounds as sources of energy and biomass. At the time, there was relatively little known about the biochemistry of this nutritional strategy. This was very fruitful and the area was the focus of his subsequent research. He was appointed as a lecturer in
218:
on understanding the biosynthesis of sugars in plants for two years. This involved the use of radioactive isotopes of carbon dioxide in rapid biochemical reactions, and he learnt the analytical techniques to identify the reaction products. In 1955 he returned to the UK to a post at the UK
302:. His personal experience with applications of science to industry supported the development of applied science as well as research at Bath. He was a member of the UK National Committee for Microbiology from 1985 until 1990, that provided advice to the UK government.
179:
In 1943 he was award a County
Scholarship for university study and he then studied for a B.Sc. degree in chemistry at University College of North Wales, Bangor that was awarded in 1946. He then studied physical organic chemistry for his doctoral degree supervised by
262:
and a range of analytical methods to identify the products of the enzyme reactions. Through this combined approach, they defined the biochemical pathways available to the bacterial methylotrophs for use of a range of one-carbon compounds, including
36:
144:(1926–2006) was a microbial biochemist, West Riding Professor of Microbiology and Head of Department at University of Sheffield (1965–1983) and then Vice-Chancellor of Bath University (1983–1992). He adopted techniques for
294:
project that initially aimed to use methane to grow bacteria for use as animal feed. His suggestion that methanol would be a preferable feed-stock was important in development of the technology, as was his further advice.
298:
Quayle held several academic administrative posts. From 1974 until 1976 he was Dean of the
Faculty of Science at University of Sheffield. From 1983 until 1992 Quayle was Vice-Chancellor of
648:
361:. He was awarded an honorary doctorate from the University of Göttingen in 1989, and from the Universities of Bath and Sheffield in 1992. He also served as president of the
283:. From 1970 the group used the same approach to discover that single celled fungi utilised methanol using a further variation that they termed the dihydroxyacetone cycle.
628:
623:
638:
653:
633:
523:
354:
235:
331:
251:
biochemistry at Oriel
College, University of Oxford in 1957, and then in 1963 he was invited to accept a senior lectureship in biochemistry at
618:
226:
However, he sought a post with more biochemical, rather than chemical, opportunity and through a chance meeting ended up collaborating with
643:
567:
211:
608:
658:
663:
613:
287:
141:
78:
452:
164:, Flintshire. When he was around 5, his father left the family and Quayle moved with his mother and older brother to
152:. He focused on microbes that used compounds containing one atom of carbon as their sources of energy and biomass.
246:. Quayle now changed the direction of his research to use the techniques he had learnt in the US to understand
252:
243:
185:
603:
598:
362:
313:
Quayle was the author or co-author of 107 scientific publications. Some of the most significant are:
358:
542:
498:
422:
299:
101:
The reactions of S‑triphenylbenzene and derivatives with special reference to steric hindrance
239:
189:
145:
291:
534:
490:
412:
231:
181:
173:
168:
to live with his maternal grandparents, who supported the children financially. He attended
123:
199:
In 1951 he and Yvonne
Sanderson were married. They had two children, a son and a daughter.
365:
from 1990 to 1993. He was awarded an
Honorary Fellowship by Bangor University in 1996.
247:
592:
350:
227:
215:
546:
502:
426:
280:
276:
272:
169:
478:
318:
35:
255:, and then promoted to the West Riding Professorship of Microbiology in 1965.
275:
and carbon dioxide. As a result, they characterised the four variants on the
258:
His research group made use of radioactive labelling as well as isolation of
220:
193:
149:
538:
417:
400:
268:
494:
264:
259:
165:
161:
92:
317:
Quayle, J. R., Fuller, R. C., Benson, A. A. and Calvin, M. (1954)
477:
Quayle, J. R.; Fuller, R. C.; Benson, A. A.; Calvin, M. (1954).
196:
insects. This led to the award of a second PhD degree in 1952.
210:
Following his research at
Cambridge, in 1953 Quayle moved to
401:"JOHN RODNEY QUAYLE 18 November 1926 — 26 February 2006"
219:
government's
Tropical Products Institute to work on
122:
91:
74:
66:
58:
50:
42:
23:
453:"Professor Rodney Quayle - Leading microbiologist"
479:"Enzymatic carboxylation of ribulose diphosphate"
319:Enzymatic carboxylation of ribulose diphosphate.
446:
444:
442:
440:
438:
436:
394:
392:
390:
388:
386:
384:
382:
380:
378:
277:ribulose monophosphate pathway (RuMP pathway)
8:
649:Vice-chancellors of the University of Bath
34:
20:
416:
16:British microbial biochemist and academic
629:Academics of the University of Cambridge
624:Academics of the University of Sheffield
332:Microbial assimilation of C-1 compounds.
374:
290:company during the development of the
192:on the blood pigment molecules of the
639:Academics of the University of Oxford
7:
654:People educated at Alun School, Mold
634:Academics of the University of Bath
568:"Quayle; John Rodney (1926 - 2006)"
238:for Research in Cell Metabolism at
128:Edward D. Hughes; Alexander R. Todd
110:Colouring matters of the Aphididae
349:In 1978 Quayle was elected to the
212:University of California, Berkeley
14:
524:"John Rodney Quayle bibliography"
234:and the glycerate pathway at the
451:Kornberg, Hans (11 April 2006).
363:Society for General Microbiology
335:Biochemical Society Transactions
1:
399:Anthony, Christopher (2015).
286:From 1967 Quayle advised the
619:Fellows of the Royal Society
146:dissecting enzymic reactions
54:2006 (aged 79–80)
644:Alumni of Bangor University
156:Personal life and education
79:Fellow of the Royal Society
680:
405:Biogr. Mem. Fellows R. Soc
202:He died 26 February 2006.
353:and was also awarded the
230:to characterise both the
132:
84:
33:
139:John Rodney (Rod) Quayle
25:John Rodney (Rod) Quayle
609:British microbiologists
253:University of Sheffield
186:University of Cambridge
659:People from Flintshire
539:10.1098/rsbm.2015.0008
418:10.1098/rsbm.2015.0008
214:, USA and worked with
279:and key parts of the
242:that was directed by
355:CIBA Medal and Prize
330:J. R. Quayle (1980)
305:He retired in 1992.
664:People from Hoylake
614:British biochemists
495:10.1021/ja01642a089
359:Biochemical Society
184:. He then moved to
170:Alun Grammar School
160:Quayle was born in
300:University of Bath
148:using radioactive
572:The Royal Society
531:The Royal Society
489:(13): 3610–3611.
322:J. Am. Chem. Soc.
240:Oxford University
190:Alexander R. Todd
136:
135:
124:Doctoral advisors
86:Scientific career
671:
583:
582:
580:
578:
564:
558:
557:
555:
553:
528:
520:
514:
513:
511:
509:
483:J. Am. Chem. Soc
474:
468:
467:
465:
463:
448:
431:
430:
420:
396:
232:glyoxylate cycle
188:and worked with
182:Edward D. Hughes
115:
106:
62:Yvonne Sanderson
38:
21:
679:
678:
674:
673:
672:
670:
669:
668:
589:
588:
587:
586:
576:
574:
566:
565:
561:
551:
549:
526:
522:
521:
517:
507:
505:
476:
475:
471:
461:
459:
457:The Independent
450:
449:
434:
398:
397:
376:
371:
347:
311:
208:
158:
118:
113:
104:
29:
26:
17:
12:
11:
5:
677:
675:
667:
666:
661:
656:
651:
646:
641:
636:
631:
626:
621:
616:
611:
606:
601:
591:
590:
585:
584:
559:
515:
469:
432:
373:
372:
370:
367:
346:
343:
342:
341:
328:
310:
307:
248:methylotrophic
223:insecticides.
207:
204:
157:
154:
134:
133:
130:
129:
126:
120:
119:
117:
116:
107:
97:
95:
89:
88:
82:
81:
76:
72:
71:
68:
64:
63:
60:
56:
55:
52:
48:
47:
44:
40:
39:
31:
30:
27:
24:
15:
13:
10:
9:
6:
4:
3:
2:
676:
665:
662:
660:
657:
655:
652:
650:
647:
645:
642:
640:
637:
635:
632:
630:
627:
625:
622:
620:
617:
615:
612:
610:
607:
605:
602:
600:
597:
596:
594:
573:
569:
563:
560:
548:
544:
540:
536:
532:
525:
519:
516:
504:
500:
496:
492:
488:
484:
480:
473:
470:
458:
454:
447:
445:
443:
441:
439:
437:
433:
428:
424:
419:
414:
410:
406:
402:
395:
393:
391:
389:
387:
385:
383:
381:
379:
375:
368:
366:
364:
360:
356:
352:
351:Royal Society
344:
339:
336:
333:
329:
326:
323:
320:
316:
315:
314:
308:
306:
303:
301:
296:
293:
289:
284:
282:
278:
274:
270:
266:
261:
256:
254:
249:
245:
241:
237:
233:
229:
228:Hans Kornberg
224:
222:
217:
216:Melvin Calvin
213:
205:
203:
200:
197:
195:
191:
187:
183:
177:
175:
171:
167:
163:
155:
153:
151:
147:
143:
140:
131:
127:
125:
121:
111:
108:
102:
99:
98:
96:
94:
90:
87:
83:
80:
77:
73:
69:
65:
61:
57:
53:
49:
45:
41:
37:
32:
22:
19:
575:. Retrieved
571:
562:
550:. Retrieved
530:
518:
506:. Retrieved
486:
482:
472:
460:. Retrieved
456:
408:
404:
348:
337:
334:
324:
321:
312:
309:Publications
304:
297:
285:
281:serine cycle
273:formaldehyde
257:
225:
209:
201:
198:
178:
159:
138:
137:
109:
100:
85:
18:
604:2006 deaths
599:1926 births
411:: 331–349.
593:Categories
369:References
340:(1) 1 - 10
244:Hans Krebs
327:3610–3611
221:pyrethrin
194:Aphididae
150:carbon-14
547:88245387
503:83536564
427:88245387
269:methanol
236:MRC Unit
67:Children
577:11 July
552:11 July
508:10 July
462:10 July
357:of the
292:Pruteen
265:methane
260:enzymes
166:Cilcain
162:Hoylake
545:
501:
425:
345:Awards
206:Career
114:(1952)
112:
105:(1949)
103:
93:Theses
75:Awards
59:Spouse
543:S2CID
527:(PDF)
499:S2CID
423:S2CID
579:2021
554:2021
510:2021
464:2021
174:Mold
51:Died
46:1926
43:Born
535:doi
491:doi
413:doi
288:ICI
172:in
142:FRS
28:FRS
595::
570:.
541:.
533:.
529:.
497:.
487:76
485:.
481:.
455:.
435:^
421:.
409:61
407:.
403:.
377:^
325:76
271:,
267:,
176:.
581:.
556:.
537::
512:.
493::
466:.
429:.
415::
338:8
70:2
Text is available under the Creative Commons Attribution-ShareAlike License. Additional terms may apply.
