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InChI=InChI=1S/C21H23F2N3O4/c1-30-20-17-13(19(27)14(21(28)29)10-26(17)12-4-5-12)7-15(22)18(20)25-6-2-3-11(9-25)16(23)8-24/h7,10,12H,2-6,8-9,24H2,1H3,(H,28,29)/b16-11+
544:"Focus on JNJ-Q2, a novel fluoroquinolone, for the management of community-acquired bacterial pneumonia and acute bacterial skin and skin structure infections"
306:
368:
432:"JNJ-Q2, a new fluoroquinolone with potent in vitro activity against Staphylococcus aureus, including methicillin- and fluoroquinolone-resistant strains"
385:, which discovered JNJ-Q2. Furiex is responsible for its development and commercialization. Both oral and intravenous formulations are being developed.
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481:"In vitro antibacterial activities of JNJ-Q2, a new broad-spectrum fluoroquinolone"
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479:
Morrow BJ, He W, Amsler KM, Foleno BD, Macielag MJ, Lynch AS, Bush K (May 2010).
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7--1-cyclopropyl-6-fluoro-1,4-dihydro-8-methoxy-4-oxo-3-quinolinecarboxylic acid
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367:. Specifically, JNJ-Q2 is being actively studied for treatment of
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430:
Farrell DJ, Liverman LC, Biedenbach DJ, Jones RN (July 2011).
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Fc1c(c(OC)c2c(c1)C(=O)C(\C(=O)O)=C/N2C3CC3)N4C/C(=C(/F)CN)CCC4
18:
197:
359:
drug being developed for the treatment of acute bacterial
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and skin-structure infections and community-acquired
542:
Jones TM, Johnson SW, DiMondi VP, Wilson DT (2016).
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377:Furiex Pharmaceuticals has licensed JNJ-Q2 from
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485:Antimicrobial Agents and Chemotherapy
436:Antimicrobial Agents and Chemotherapy
7:
1547:
1545:
1565:. You can help Knowledge (XXG) by
14:
1549:
529:"Novel Fluoroquinolone (JNJ-Q2)"
252:
246:
240:
23:
388:As of 2016, tests are ongoing.
339:Key:VMKVDAAFMQKZJS-LFIBNONCSA-N
258:
234:
1:
955:Trimethoprim/sulfamethoxazole
548:Infection and Drug Resistance
1622:Fluoroquinolone antibiotics
960:Ormetoprim/sulfadimethoxine
1643:
1544:
224:Chemical and physical data
1502:
970:Pyrimethamine/sulfadoxine
531:. Furiex Pharmaceuticals.
322:
302:
111:
80:
38:, as no other articles
1561:-related article is a
869:Sulfamethoxypyridazine
369:methicillin-resistant
1342:Newer non-fluorinated
979:Other DHPS inhibitors
965:Pyrimethamine/dapsone
792:Succinylsulfathiazole
788:Phthalylsulfathiazole
672:2,4-Diaminopyrimidine
383:Johnson & Johnson
379:Janssen Pharmaceutica
371:Staphylococcus aureus
766:Acetyl sulfisoxazole
625:inhibit nucleic acid
497:10.1128/AAC.01374-09
448:10.1128/AAC.00162-11
352:is a broad-spectrum
1141:Alalevonadifloxacin
808:Intermediate-acting
561:10.2147/IDR.S105620
374:(MRSA) infections.
77:
1529:Never to phase III
1030:thereby inhibiting
1018:(inhibit bacterial
864:Sulfametoxydiazine
652:thereby inhibiting
645:(inhibit bacterial
57:for suggestions.
47:to this page from
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648:purine metabolism
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293:Interactive image
193:CompTox Dashboard
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16:Chemical compound
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1627:Antibiotic stubs
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1435:
1402:
1137:Levonadifloxacin
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1091:Fluoroquinolones
1039:
844:Sulfadimethoxine
816:Sulfamethoxazole
737:Sulfaisodimidine
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898:Other/ungrouped
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1406:Nitroimidazole
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1076:Piromidic acid
1073:
1071:Pipemidic acid
1068:
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1061:Nalidixic acid
1058:
1053:
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1043:1st generation
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922:
920:Sulfadicramide
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884:Sulfaphenazole
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742:Sulfamethizole
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719:DHPS inhibitor
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664:DHFR inhibitor
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621:Antibacterials
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491:(5): 1955–64.
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406:"CSID:9721013"
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55:Find link tool
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1612:Cyclopropanes
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1340:
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1327:
1325:
1324:Pradofloxacin
1322:
1320:
1317:
1315:
1314:Marbofloxacin
1312:
1310:
1307:
1305:
1302:
1300:
1297:
1295:
1292:
1291:
1289:
1287:
1283:
1277:
1273:
1272:Trovafloxacin
1270:
1268:
1265:
1263:
1262:Prulifloxacin
1260:
1258:
1255:
1253:
1252:Clinafloxacin
1250:
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1184:Grepafloxacin
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1108:Ciprofloxacin
1106:
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1097:
1094:
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1088:
1082:
1079:
1077:
1074:
1072:
1069:
1067:
1066:Oxolinic acid
1064:
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1054:
1052:
1049:
1048:
1046:
1044:
1040:
1037:
1034:
1027:
1022:
1021:topoisomerase
1016:
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1002:
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986:Acediasulfone
984:
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910:Sulfacetamide
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799:
798:Sulfathiourea
796:
793:
789:
785:
784:Sulfathiazole
782:
778:
775:
774:
773:
772:Sulfanilamide
770:
767:
763:
762:Sulfafurazole
760:
757:
756:Sulfasalazine
753:
752:Sulfapyridine
750:
748:
747:Sulfadimidine
745:
743:
740:
738:
735:
734:
732:
730:
726:
723:
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715:
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703:
700:
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693:
692:Pyrimethamine
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442:(7): 3631–4.
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90:Clinical data
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46:
42:
41:
37:
32:This article
30:
26:
21:
20:
1567:expanding it
1556:
1541:
1482:Lipiarmycins
1329:Sarafloxacin
1319:Orbifloxacin
1304:Enrofloxacin
1294:Danofloxacin
1267:Sitafloxacin
1247:Moxifloxacin
1242:Gemifloxacin
1237:Finafloxacin
1232:Gatifloxacin
1227:Delafloxacin
1222:Besifloxacin
1204:Tosufloxacin
1199:Temafloxacin
1194:Sparfloxacin
1189:Pazufloxacin
1179:Balofloxacin
1174:Levofloxacin
1133:Nadifloxacin
1128:Lomefloxacin
948:Combinations
930:Sulfametrole
915:Sulfaclozine
821:Sulfadiazine
729:Short-acting
714:Sulfonamides
702:Trimethoprim
551:
547:
537:
523:
488:
484:
474:
439:
435:
425:
413:. Retrieved
400:
387:
381:, a unit of
376:
370:
349:
348:
59:
33:
1617:Piperidines
1515:from market
1490:Fidaxomicin
1462:Rifapentine
1415:Secnidazole
1408:derivatives
1349:Nemonoxacin
1309:Ibafloxacin
1257:Garenoxacin
1146:Norfloxacin
996:Solasulfone
935:Sulfanitran
889:Sulfamazone
849:Sulfadoxine
836:Long-acting
826:Sulfamoxole
697:Tetroxoprim
677:Brodimoprim
654:DNA and RNA
642:Antifolates
276: g·mol
142:878592-87-1
107:Identifiers
1606:Categories
1559:antibiotic
1452:Rifampicin
1439:Rifamycins
1397:inhibitors
1378:Novobiocin
1354:Ozenoxacin
1299:Difloxacin
1286:Veterinary
1156:Rufloxacin
1151:Pefloxacin
1123:Fleroxacin
1056:Flumequine
1026:DNA gyrase
1015:Quinolones
874:Sulfaperin
687:Ormetoprim
656:synthesis)
554:: 119–28.
410:ChemSpider
392:References
281:3D model (
269:Molar mass
182:070SV15RJA
153:ChemSpider
133:CAS Number
116:IUPAC name
53:; try the
40:link to it
1525:Phase III
1513:Withdrawn
1472:Rifalazil
1467:Rifaximin
1457:Rifabutin
1431:synthesis
1392:Anaerobic
1363:Related (
1113:Ofloxacin
1081:Rosoxacin
1051:Cinoxacin
1001:Sulfoxone
854:Sulfalene
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