181:
Zhang, along with the help from Johns
Hopkins Laboratories, is also credited for the creation of a new technique referred to as CAESAR. This technique was designed to experimentally identify substrates for unique kinases. It results in high-quality KSRs.
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108:. In 2013, she was promoted to full professor in the departments of pharmacology and molecular sciences, Solomon H. Snyder Department of Neuroscience and department of oncology, and department of chemical and biomolecular engineering.
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In 2015, Zhang relocated her lab to UCSD, where she is a professor in the departments of pharmacology, bioengineering, and chemistry and biochemistry. She is a member of the
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55:; born February 29, 1972) is a Chinese-American biochemist. She is a professor of pharmacology, chemistry and biochemistry, and biomedical engineering at the
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Mo, Gary C. H.; Ross, Brian; Hertel, Fabian; Manna, Premashis; Yang, Xinxing; Greenwald, Eric; Booth, Chris; Plummer, Ashlee M.; Tenner, Brian (April 2017).
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ratio or fluorescence intensity based on kinase activity. Zhang and her lab have used this method to study several kinases, including
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Tsien, Roger Y.; Alice Y. Ting; Campbell, Robert E.; Zhang, Jin (December 2002). "Creating new fluorescent probes for cell biology".
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Following her postdoc at UCSD, Zhang joined the faculty in the department of pharmacology and molecular sciences at the
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Zhou, Xin; Clister, Terri L.; Lowry, Pamela R.; Seldin, Marcus M.; Wong, G. William; Zhang, Jin (2015-03-17).
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554:"Genetically Encoded Fluorescent Biosensors Illuminate the Spatiotemporal Regulation of Signaling Networks"
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1014:"Dr. Jin Zhang selected for the 2019 ICBS Global Lectureship - International Chemical Biology Society"
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703:"A genetically encoded fluorescent reporter reveals oscillatory phosphorylation by protein kinase C"
884:"Genetically encoded biosensors for visualizing live-cell biochemical activity at super-resolution"
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194:
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611:"Genetically encoded reporters of protein kinase A activity reveal impact of substrate tethering"
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1038:"UC San Diego Researchers Inducted to Renowned Medical and Biological Engineering Organization"
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115:. Zhang is also director and cofounder of the Bio-Optical Probe Advancement Center at UCSD.
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Zhang was born in
Beijing, China. She received her Bachelor of Science in chemistry from
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817:"Widely accessible method for superresolution fluorescence imaging of living systems"
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Violin, Jonathan D.; Zhang, Jin; Tsien, Roger Y.; Newton, Alexandra C. (2003-06-09).
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610:
28:
20:
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964:"NIH Director's Pioneer Award Program - 2009 Award Recipients | NIH Common Fund"
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Journal of
Histochemistry and Cytochemistry Lecture, Experimental Biology (2017)
821:
Proceedings of the
National Academy of Sciences of the United States of America
615:
Proceedings of the
National Academy of Sciences of the United States of America
431:
337:
142:. Genetically encoded biosensors utilize a kinase-specific substrate fused to
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Dedecker, Peter; Mo, Gary C. H.; Dertinger, Thomas; Zhang, Jin (2012-07-03).
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178:(FLINC), which has been used to generate super-resolution kinase biosensors
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Fellows of the
American Institute for Medical and Biological Engineering
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Weidmann, Alyson (2018-07-20). "In
Memoriam: Roger Tsien (1952—2016)".
135:
46:
677:"Protein kinase A activated in the nucleus as well as the cytoplasm"
72:
in
Beijing in 1995. She completed her PhD with David G. Lynn at the
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Fellows of the
American Association for the Advancement of Science
159:
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American
Society for Pharmacology and Experimental Therapeutics
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American Society for Pharmacology and Experimental Therapeutics
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Zhang, J.; Ma, Y.; Taylor, S. S.; Tsien, R. Y. (2001-12-18).
249:
Finalist Prize, Creative Promise in Biomedical Research, the
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Postdoctoral fellowship, La Jolla Interfaces in Science and
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Greenwald, Eric C.; Mehta, Sohum; Zhang, Jin (2018-12-14).
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210:
Young Scientist Research Award, Bioorganic Chemistry (2003)
760:"Dynamic Visualization of mTORC1 Activity in Living Cells"
418:
Zhang, Jin (August 2016). "An Interview with Jin Zhang".
297:
American Institute for Medical and Biological Engineering
989:"2015 Recipients of NCI Outstanding Investigator Awards"
132:
genetically encoded fluorescent protein-based biosensors
190:
Zhang has received many honors and awards including:
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and a phosphoamino acid binding domain, which change
176:
fluorescence fluctuation increase by contact imaging
275:
American Association for the Advancement of Science
168:
photochromic stochastic optical fluctuation imaging
162:, among others. The Zhang group has also worked on
104:in 2003. At Johns Hopkins, she was a member of the
8:
172:super-resolution optical fluctuation imaging
130:The Zhang group is interested in developing
1142:University of California, San Diego faculty
215:Flight Attendant Medical Research Institute
102:Johns Hopkins University School of Medicine
283:Outstanding Investigator Award (2015-2022)
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106:Sidney Kimmel Comprehensive Cancer Center
478:"Editorial Board: Cell Chemical Biology"
372:UC San Diego Chemistry and Biochemistry
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118:Zhang is an editorial board member for
1197:21st-century American women scientists
1192:20th-century American women scientists
1147:Chinese emigrants to the United States
290:International Chemical Biology Society
220:National Scientist Development Award,
213:FAMRI Young Clinical Scientist Award,
197:Fund, the University of Chicago (2000)
503:Nature Reviews Molecular Cell Biology
230:Non-tenured Faculty Award (2006–2008)
7:
256:John J. Abel Award in Pharmacology,
90:University of California, San Diego
57:University of California, San Diego
940:"Welcome to Zhang Lab | Zhang Lab"
454:"Welcome to Zhang Lab | Zhang Lab"
420:Trends in Pharmacological Sciences
14:
1172:21st-century American biochemists
138:, similar to those developed for
1137:Johns Hopkins University faculty
264:Pfizer Award in Enzyme Chemistry
160:mechanistic target of rapamycin
1167:20th-century American chemists
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42:
1:
1132:University of Chicago alumni
776:10.1016/j.celrep.2015.02.031
244:NIH Director's Pioneer Award
234:Margaret Oakley Dayoff Award
31:when mentioning individuals.
707:The Journal of Cell Biology
570:10.1021/acs.chemrev.8b00333
16:Chinese-American biochemist
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1127:Tsinghua University alumni
1112:American women biochemists
432:10.1016/j.tips.2016.05.009
338:10.1021/acschembio.8b00617
222:American Heart Association
208:Gordon Research Conference
18:
993:National Cancer Institute
292:Global Lectureship (2019)
268:American Chemical Society
1187:American women academics
1157:Academic journal editors
1018:www.chemical-biology.org
164:super-resolution imaging
64:Early life and education
27:. This article uses
19:The native form of this
1182:Biologists from Beijing
1122:American women chemists
842:10.1073/pnas.1204917109
399:www.hopkinsmedicine.org
202:Burroughs Wellcome Fund
170:(pcSOFI), a variant of
76:in 2000, and conducted
1177:Educators from Beijing
1117:Chinese women chemists
636:10.1073/pnas.211566798
166:techniques, including
1102:Chemists from Beijing
719:10.1083/jcb.200302125
120:Cell Chemical Biology
78:postdoctoral research
74:University of Chicago
944:jinzhanglab.ucsd.edu
458:jinzhanglab.ucsd.edu
326:ACS Chemical Biology
144:fluorescent proteins
113:Moores Cancer Center
1107:Chinese biochemists
970:. 18 September 2018
833:2012PNAS..10910909D
827:(27): 10909–10914.
627:2001PNAS...9814997Z
621:(26): 14997–15002.
564:(24): 11707–11794.
238:Biophysical Society
195:Lucent Technologies
70:Tsinghua University
968:commonfund.nih.gov
900:10.1038/nmeth.4221
29:Western name order
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186:Honors and awards
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888:Nature Methods
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21:personal name
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1021:. Retrieved
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1008:
997:. Retrieved
995:. 2015-10-14
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683:. 2012-06-27
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368:"Zhang, Jin"
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1092:1972 births
395:"Jin Zhang"
246:(2009–2014)
224:(2005-2008)
217:(2004-2009)
204:(2002-2003)
1086:Categories
1071:2022-02-12
1047:2019-04-08
1023:2019-04-08
999:2019-04-08
974:2019-04-08
949:2020-05-08
687:2019-04-08
487:2019-04-08
463:2020-05-08
404:2020-03-29
311:References
908:1548-7105
851:1091-6490
784:2211-1247
727:0021-9525
645:0027-8424
578:1520-6890
523:1471-0080
346:1554-8929
52:Zhāng Jǐn
35:Jin Zhang
25:Zhang Jin
926:28288122
869:22711840
802:25772363
745:12782683
663:11752448
596:30550275
539:11588100
531:12461557
440:27290877
378:29 March
354:51703317
126:Research
1066:Default
917:5388356
860:3390831
829:Bibcode
793:4567530
736:2172956
623:Bibcode
587:7462118
136:kinases
88:at the
39:Chinese
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865:PMID
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723:ISSN
659:PMID
641:ISSN
592:PMID
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527:PMID
519:ISSN
436:PMID
380:2020
342:ISSN
148:FRET
134:for
84:and
912:PMC
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855:PMC
837:doi
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