25:
163:, which has pioneered the development and early introduction of numerous innovative diagnoses and treatments in human genetics and infertility, and is now an international company in these fields. The institute was the first in the United States to introduce transvaginal non-surgical IVF (replacing
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where he headed the
Section on Human Biochemical Genetics. He founded and was first Director of the Interinstitute Program in Medical Genetics, remaining at the National Institutes of Health until 1983. During this period, the major research contributions of Schulman and his associates were in the
370:
Chrousos, George P.; Evans, Mark I.; Loriaux, D. Lynn; McCluskey, James; Fletcher, John C.; Schulman, Joseph D. (1985). "Prenatal
Therapy in Congenital Adrenal Hyperplasia Attempted Prevention of Abnormal External Genital Masculinization by Pharmacologic Suppression of the Fetal Adrenal Gland in
219:
with sorted sperm. This innovation was notable for improving the ability to choose the sex of a child conceived by the above-cited methods. Decades after its introduction, fetal genetic testing is increasingly used, despite some initial hesitancy to adopt it. The institute, under
Schulman's
79:, New York. He graduated from Harvard Medical School in 1966 and trained in pediatrics, genetics, and obstetrics and gynecology at Massachusetts General Hospital, the National Institutes of Health, and Cornell-New York Hospital Medical Center. Schulman worked at
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Pellefigue, F; Butler, JD; Spielberg, SP; Hollenberg, MD; Goodman, SI; Schulman, JD (1976). "Normal amino acid uptake by cultured human fibroblasts does not require gamma-glutamyl transpeptidase".
231:
Schulman was CEO of the
Genetics & IVF Institute until 1998, and remains chairman of its board of directors. He previously served as an affiliate professor at the medical schools of
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and ocular crystals characteristic of cystinosis, and this treatment is widely utilized today. The prevention of abnormal genital masculinization in female fetuses with
772:
752:
470:
Schulman, JD; Black, SH; Handyside, A; Nance, WE (1996). "Preimplantation genetic testing for
Huntington disease and certain other dominantly inherited disorders".
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Gahl, W.; Bashan, N; Tietze, F; Bernardini, I; Schulman, J. (1982). "Cystine transport is defective in isolated leukocyte lysosomes from patients with cystinosis".
515:"Births of normal daughters after MicroSort sperm separation and intrauterine insemination, in-vitro fertilization, or intracytoplasmic sperm injection"
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can modify the proportion of viable X-bearing and Y-bearing sperm and that such technology can increase the proportion of girls or boys born after
67:(born 1941) is an American physician, medical researcher, and biomedical entrepreneur in the fields of genetic diseases and human reproduction.
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211:. More recently, Schulman and his colleagues have established that flow-cytometric sorting (MicroSort) of living
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203:. Schulman and associates also developed the world's first system for the use of non-disclosing preimplantation
95:(IVF). He is recognized as a pioneer and authority in the fields of fetal medicine, prenatal genetics, and IVF.
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gamma-glutamyl transpeptidase was not, contrary to current theory, required for normal transcellular
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direction, was responsible for starting the first modern genetics/infertility treatment center in
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and now the standard method worldwide), and also to report pregnancies using ICSI (
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genes, considered to be responsible for a significant fraction of hereditary
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to the mother, first proposed and utilized by
Schulman and his colleagues at
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175:. The institute also was one of the first centers in the world to introduce
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caused by hereditary absence of the transmembrane lysosomal carrier for
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112:, especially diseases of sulfur metabolism. They demonstrated that
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may have been created or edited in return for undisclosed payments
446:"Breaking Ranks, Lab Offers Test to Assess Risk of Breast Cancer"
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18:
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Fugger, E.; Black, SH; Keyvanfar, K; Schulman, JD (1998).
40:. It may require cleanup to comply with Knowledge (XXG)'s
556:"Researchers Report Success in Method to Pick Baby's Sex"
105:
National
Institute of Child Health and Human Development
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269:Baby Doctors: Probing the Limits of Fetal Medicine
228:, one of the largest IVF programs in the world.
660:"Genetic Testing Falls Short of Public Embrace"
199:, and the first to offer prenatal testing for
686:Robert G. Edwards : a personal viewpoint
156:, has also become a widely accepted therapy.
8:
758:University of California, San Diego faculty
132:transport. Schulman and David Cogan of the
373:Annals of the New York Academy of Sciences
103:In 1974, Schulman joined the staff of the
530:
773:Academics of the University of Cambridge
753:Virginia Commonwealth University faculty
246:, a personal account of Nobel Laureate,
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244:Robert G. Edwards: A Personal Viewpoint
632:Wadman, Meredith (February 19, 2001).
140:eyedrops for treatment of the painful
7:
237:University of California, San Diego
179:(CVS) as an earlier alternative to
171:) for the treatment of severe male
36:, a violation of Knowledge (XXG)'s
580:Grady, Denise (February 6, 2007).
554:Kolata, Gina (September 8, 1998).
484:10.1111/j.1399-0004.1996.tb04327.x
393:10.1111/j.1749-6632.1985.tb14600.x
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233:Virginia Commonwealth University
169:intracytoplasmic sperm injection
23:
658:Kolata, Gina (March 27, 1998).
136:were also the first to utilize
606:Belkin, Lisa (July 25, 1999).
444:Kolata, Gina (April 1, 1996).
425:. Genetics & IVF Institute
159:In 1984, Schulman founded the
148:by prenatal administration of
146:congenital adrenal hyperplasia
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763:Harvard Medical School alumni
271:. New York: Delacorte Press.
75:Schulman was born in 1941 in
733:American medical researchers
713:Genetics & IVF Institute
684:Schulman, Joseph D. (2010).
349:10.1016/0006-291X(76)90221-7
161:Genetics & IVF Institute
110:inborn errors of metabolism
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242:Schulman is the author of
768:Cornell University alumni
177:chorionic villus sampling
118:lysosomal storage disease
532:10.1093/humrep/13.9.2367
314:10.1126/science.7112129
85:Robert Geoffrey Edwards
207:for the prevention of
134:National Eye Institute
124:, and proved that the
93:in-vitro fertilization
65:Joseph Daniel Schulman
728:American andrologists
267:Kolata, Gina (1990).
46:neutral point of view
748:American geneticists
634:"So You Want a Girl"
81:Cambridge University
385:1985NYASA.458..156C
306:1982Sci...217.1263G
16:American geneticist
664:The New York Times
612:The New York Times
608:"Getting the Girl"
586:The New York Times
560:The New York Times
519:Human Reproduction
450:The New York Times
209:Huntington disease
185:prenatal diagnosis
472:Clinical Genetics
278:978-0-385-29938-1
248:Robert G. Edwards
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38:terms of use
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738:1941 births
478:(2): 57–8.
213:human sperm
173:infertility
165:laparoscopy
142:photophobia
722:Categories
254:References
138:cysteamine
130:amino acid
114:cystinosis
83:with Drs.
500:45703511
429:20 April
409:46197049
371:Utero".
357:15625873
235:and the
222:Shanghai
77:Brooklyn
638:Fortune
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492:8740912
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381:Bibcode
322:7112129
302:Bibcode
294:Science
122:cystine
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126:enzyme
99:Career
496:S2CID
405:S2CID
226:China
193:BRCA2
189:BRCA1
116:is a
690:ISBN
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431:2013
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318:PMID
273:ISBN
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Text is available under the Creative Commons Attribution-ShareAlike License. Additional terms may apply.
