Knowledge (XXG)

KAT6A

Source πŸ“

334: 311: 208: 233: 2348: 585: 592: 340: 239: 2333: 29: 2376: 1393:
Borrow J, Stanton VP, Andresen JM, Becher R, Behm FG, Chaganti RS, Civin CI, Disteche C, DubΓ© I, Frischauf AM, Horsman D, Mitelman F, Volinia S, Watmore AE, Housman DE (September 1996). "The translocation t(8;16)(p11;p13) of acute myeloid leukaemia fuses a putative acetyltransferase to the
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in the KAT6A gene. The main characteristics of this syndrome are developmental delay, impaired intellectual development, speech delay, microcephaly, cardiac anomalies, and gastrointestinal complications.
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Borrow J, Stanton VP, Andresen JM, et al. (1996). "The translocation t(8;16)(p11;p13) of acute myeloid leukaemia fuses a putative acetyltransferase to the CREB-binding protein".
2347: 2093:"MOZ-TIF2 alters cofactor recruitment and histone modification at the RARbeta2 promoter: differential effects of MOZ fusion proteins on CBP- and MOZ-dependent activators" 347: 246: 1511:
Kennedy, J., Goudie, D., Blair, E. et al. KAT6A Syndrome: genotype–phenotype correlation in 76 patients with pathogenic KAT6A variants. Genet Med 21, 850–860 (2019).
915: 896: 169: 2249:"Posttranslational acetylation of the human immunodeficiency virus type 1 integrase carboxyl-terminal domain is dispensable for viral replication" 2050:"Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes" 2445: 1358: 2421: 2312: 1340: 2440: 2332: 52: 333: 1659: 1139: 1146: 310: 1376: 1327: 1306: 1646:
Chaffanet M, Gressin L, Preudhomme C, et al. (2000). "MOZ is fused to p300 in an acute monocytic leukemia with t(8;22)".
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Arboleda-Tham syndrome (ARTHS), also referred to as KAT6A Syndrome (Arboleda-Tham Syndrome), is a rare autosomal dominant
1302: 1851:"MOZ-TIF2-induced acute myeloid leukemia requires the MOZ nucleosome binding motif and TIF2-mediated recruitment of CBP" 149: 346: 245: 339: 238: 2414: 2305: 2128:"A protein-protein interaction network for human inherited ataxias and disorders of Purkinje cell degeneration" 960: 157: 941: 1265: 2407: 2298: 1809: 1538: 221: 136: 1277: 1122: 1118: 1093: 1067: 1063: 1038: 1034: 1030: 1763:"MOZ and MORF histone acetyltransferases interact with the Runt-domain transcription factor Runx2" 2235: 2157: 1671: 1599: 1562: 1419: 181: 1798:"Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences" 1613:"A novel fusion between MOZ and the nuclear receptor coactivator TIF2 in acute myeloid leukemia" 1097: 1042: 1720:"Activation of AML1-mediated transcription by MOZ and inhibition by the MOZ-CBP fusion protein" 2356:: Crystal structure of human MYST histone acetyltransferase 3 in complex with acetylcoenzyme A 2278: 2227: 2192: 2149: 2114: 2079: 2036: 1993: 1950: 1915: 1872: 1837: 1784: 1749: 1706: 1663: 1634: 1591: 1554: 1480: 1411: 1273: 1269: 1240: 1232: 584: 129: 45: 2391: 2268: 2260: 2217: 2182: 2139: 2104: 2069: 2061: 2026: 2018: 1983: 1975: 1964:"MOZ-TIF2 inhibits transcription by nuclear receptors and p53 by impairment of CBP function" 1940: 1905: 1897: 1862: 1827: 1817: 1774: 1739: 1731: 1696: 1655: 1624: 1583: 1546: 1470: 1403: 426: 357: 301: 256: 591: 177: 2171:"Substrate and functional diversity of lysine acetylation revealed by a proteomics survey" 1529:
Schuler GD, Boguski MS, Stewart EA, et al. (1996). "A gene map of the human genome".
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Autosomal dominant intellectual disability-craniofacial anomalies-cardiac defects syndrome
401: 140:, MOZ, MYST3, RUNXBP2, ZC2HC6A, ZNF220, MRD32, MYST-3, lysine acetyltransferase 6A, ARTHS 1813: 1542: 2273: 2248: 2074: 2049: 2031: 2006: 1244: 28: 1988: 1963: 1910: 1885: 1867: 1850: 1832: 1797: 1744: 1719: 830: 825: 820: 815: 810: 805: 800: 795: 790: 785: 780: 775: 770: 765: 760: 744: 739: 734: 729: 724: 719: 714: 709: 704: 688: 683: 678: 673: 668: 663: 658: 653: 648: 643: 638: 633: 2434: 1603: 1423: 620: 2161: 1675: 161: 2387: 2239: 2206:"Global, in vivo, and site-specific phosphorylation dynamics in signaling networks" 1979: 419: 198: 2187: 2170: 1566: 1550: 185: 1363:
National Center for Biotechnology Information, U.S. National Library of Medicine
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National Center for Biotechnology Information, U.S. National Library of Medicine
1228: 2222: 2205: 2144: 2127: 1735: 1685:"The monocytic leukemia zinc finger protein MOZ is a histone acetyltransferase" 502: 1886:"Transcriptional regulation of the human MIP-1alpha promoter by RUNX1 and MOZ" 318: 215: 165: 2022: 1629: 1612: 1929:"Complete sequencing and characterization of 21,243 full-length human cDNAs" 1512: 1247: 1236: 860: 562: 440: 385: 372: 284: 271: 173: 2282: 2231: 2196: 2153: 2118: 2109: 2092: 2083: 2040: 1997: 1954: 1919: 1876: 1841: 1822: 1788: 1779: 1762: 1753: 1710: 1701: 1684: 1667: 1484: 1475: 1458: 1638: 1595: 1558: 1415: 1377:"Entrez Gene: MYST3 MYST histone acetyltransferase (monocytic leukemia) 3" 1186: 1181: 2264: 1901: 1436: 1170: 1005: 986: 1660:
10.1002/(SICI)1098-2264(200006)28:2<138::AID-GCC2>3.0.CO;2-2
2065: 972: 927: 1587: 1407: 106: 102: 98: 94: 90: 86: 82: 78: 74: 1459:"MOZ and MORF, two large MYSTic HATs in normal and cancer stem cells" 1154: 882: 2375: 2007:"Acetylation of HIV-1 integrase by p300 regulates viral integration" 1498: 1945: 1928: 845: 841: 2383: 1220:
The KAT6A protein contains two nuclear localization domains, a C
1209: 153: 2294: 600: 2290: 1212:. This gene is located on human chromosome 8, band 8p11.21. 2005:
Cereseto A, Manganaro L, Gutierrez MI, et al. (2005).
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Strausberg RL, Feingold EA, Grouse LH, et al. (2003).
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domain. This structure suggests that KAT6A functions as a
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positive regulation of transcription by RNA polymerase II
1718:
Kitabayashi I, Aikawa Y, Nguyen LA, et al. (2002).
409: 2395: 1499:"OMIM Entry - # 616268 - ARBOLEDA-THAM SYNDROME; ARTHS" 811:
regulation of signal transduction by p53 class mediator
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Collins HM, Kindle KB, Matsuda S, et al. (2006).
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Kimura K, Wakamatsu A, Suzuki Y, et al. (2006).
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Kindle KB, Troke PJ, Collins HM, et al. (2005).
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Deguchi K, Ayton PM, Carapeti M, et al. (2003).
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Pelletier N, Champagne N, Stifani S, Yang XJ (2002).
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Carapeti M, Aguiar RC, Goldman JM, Cross NC (1998).
2341:: Solution Structure of a CCHC Zinc Finger from MOZ 1243:. KAT6A is important for the proper development of 1205:), is an enzyme that, in humans, is encoded by the 1111: 1086: 1056: 1023: 801:
negative regulation of transcription, DNA-templated
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positive regulation of transcription, DNA-templated
1927:Ota T, Suzuki Y, Nishikawa T, et al. (2004). 1319: 1317: 1315: 1298: 1296: 1294: 2204:Olsen JV, Blagoev B, Gnad F, et al. (2006). 356: 255: 2247:Topper M, Luo Y, Zhadina M, et al. (2007). 16:Protein-coding gene in the species Homo sapiens 2169:Kim SC, Sprung R, Chen Y, et al. (2006). 1324:GRCm38: Ensembl release 89: ENSMUSG00000031540 2415: 2306: 1388: 1386: 8: 1303:GRCh38: Ensembl release 89: ENSG00000083168 2422: 2408: 2313: 2299: 2291: 2126:Lim J, Hao T, Shaw C, et al. (2006). 1683:Champagne N, Pelletier N, Yang XJ (2001). 856: 776:regulation of transcription, DNA-templated 715:MOZ/MORF histone acetyltransferase complex 616: 397: 296: 193: 63: 2272: 2221: 2186: 2143: 2108: 2073: 2030: 1987: 1944: 1909: 1866: 1831: 1821: 1778: 1743: 1700: 1628: 1513:https://doi.org/10.1038/s41436-018-0259-2 1474: 2328: 1290: 18: 684:H4 histone acetyltransferase activity 361: 322: 317: 260: 219: 214: 7: 2372: 2370: 2394:. You can help Knowledge (XXG) by 1108: 1083: 1053: 1020: 996: 977: 951: 932: 906: 887: 659:histone acetyltransferase activity 644:transcription coactivator activity 579: 497: 435: 414: 14: 745:histone acetyltransferase complex 2374: 2346: 2331: 1457:Yang XJ, Ullah M (August 2007). 590: 583: 345: 338: 332: 309: 244: 237: 231: 206: 27: 1980:10.1128/MCB.25.3.988-1002.2005 1199:K(lysine) acetyltransferase 6A 601:More reference expression data 563:More reference expression data 1: 2446:Human chromosome 8 gene stubs 1868:10.1016/S1535-6108(03)00051-5 330: 229: 2188:10.1016/j.molcel.2006.06.026 1884:Bristow CA, Shore P (2003). 1802:Proc. Natl. Acad. Sci. U.S.A 1551:10.1126/science.274.5287.540 781:transcription, DNA-templated 771:myeloid cell differentiation 649:transcription factor binding 2441:Genes on human chromosome 8 2462: 2369: 2223:10.1016/j.cell.2006.09.026 2145:10.1016/j.cell.2006.03.032 1257: 674:acetyltransferase activity 517:retinal pigment epithelium 2326: 1359:"Mouse PubMed Reference:" 1341:"Human PubMed Reference:" 1185: 1180: 1176: 1169: 1153: 1134: 1115: 1090: 1079: 1060: 1027: 1016: 1003: 999: 984: 980: 971: 958: 954: 939: 935: 926: 913: 909: 894: 890: 881: 866: 859: 855: 839: 619: 615: 598: 582: 573: 560: 509: 500: 447: 438: 408: 400: 396: 379: 366: 329: 308: 299: 295: 278: 265: 228: 205: 196: 192: 147: 144: 134: 127: 122: 71: 66: 49: 44: 39: 35: 26: 21: 2023:10.1038/sj.emboj.7600770 1736:10.1093/emboj/20.24.7184 1648:Genes Chromosomes Cancer 1630:10.1182/blood.V91.9.3127 761:animal organ development 669:acyltransferase activity 455:internal globus pallidus 1394:CREB-binding protein". 1147:Chr 8: 23.35 – 23.43 Mb 1140:Chr 8: 41.93 – 42.05 Mb 2110:10.1074/jbc.M602633200 1823:10.1073/pnas.242603899 1780:10.1038/sj.onc.1205367 1702:10.1038/sj.onc.1204114 1476:10.1038/sj.onc.1210609 1266:developmental disorder 1254:Arboleda-Tham syndrome 826:histone H4 acetylation 821:chromatin organization 796:histone H3 acetylation 1447:omim.org/entry/601408 2265:10.1128/JVI.02257-06 1278:frameshift mutations 1268:, caused by various 634:transferase activity 324:Chromosome 8 (mouse) 222:Chromosome 8 (human) 67:List of PDB id codes 40:Available structures 1814:2002PNAS...9916899M 1543:1996Sci...274..540S 816:histone acetylation 806:protein acetylation 791:cellular senescence 766:nucleosome assembly 479:epithelium of colon 2382:This article on a 2066:10.1101/gr.4039406 1902:10.1093/nar/gkg401 961:ENSMUSG00000031540 754:Biological process 698:Cellular component 627:Molecular function 525:tibiofemoral joint 2403: 2402: 2364: 2363: 1890:Nucleic Acids Res 1808:(26): 16899–903. 1588:10.1038/ng0996-33 1408:10.1038/ng0996-33 1241:acetyltransferase 1233:acetyltransferase 1196: 1195: 1192: 1191: 1165: 1164: 1130: 1129: 1105: 1104: 1075: 1074: 1050: 1049: 1012: 1011: 993: 992: 967: 966: 948: 947: 922: 921: 903: 902: 851: 850: 654:metal ion binding 611: 610: 607: 606: 569: 568: 556: 555: 537:cerebellar vermis 494: 493: 392: 391: 291: 290: 186:KAT6A - orthologs 118: 117: 114: 113: 50:Ortholog search: 2453: 2424: 2417: 2410: 2378: 2371: 2350: 2335: 2315: 2308: 2301: 2292: 2286: 2276: 2243: 2225: 2200: 2190: 2165: 2147: 2122: 2112: 2103:(25): 17124–33. 2087: 2077: 2044: 2034: 2001: 1991: 1958: 1948: 1923: 1913: 1880: 1870: 1845: 1835: 1825: 1792: 1782: 1757: 1747: 1714: 1704: 1679: 1642: 1632: 1607: 1570: 1515: 1509: 1503: 1502: 1495: 1489: 1488: 1478: 1454: 1448: 1445: 1439: 1434: 1428: 1427: 1390: 1381: 1380: 1373: 1367: 1366: 1355: 1349: 1348: 1337: 1331: 1321: 1310: 1300: 1216:Protein function 1178: 1177: 1149: 1142: 1125: 1109: 1100: 1084: 1080:RefSeq (protein) 1070: 1054: 1045: 1021: 997: 978: 952: 933: 907: 888: 857: 679:zinc ion binding 617: 603: 594: 587: 580: 565: 505: 503:Top expressed in 498: 459:lactiferous duct 443: 441:Top expressed in 436: 415: 398: 388: 375: 364: 349: 342: 336: 325: 313: 297: 287: 274: 263: 248: 241: 235: 224: 210: 194: 188: 139: 132: 109: 64: 58: 37: 36: 31: 19: 2461: 2460: 2456: 2455: 2454: 2452: 2451: 2450: 2431: 2430: 2429: 2428: 2367: 2365: 2360: 2357: 2351: 2342: 2336: 2322: 2319: 2289: 2246: 2203: 2168: 2125: 2090: 2047: 2017:(17): 3070–81. 2004: 1974:(3): 988–1002. 1968:Mol. Cell. Biol 1961: 1926: 1896:(11): 2735–44. 1883: 1848: 1795: 1773:(17): 2729–40. 1760: 1730:(24): 7184–96. 1717: 1682: 1645: 1610: 1573: 1537:(5287): 540–6. 1528: 1524: 1522:Further reading 1519: 1518: 1510: 1506: 1497: 1496: 1492: 1469:(37): 5408–19. 1456: 1455: 1451: 1446: 1442: 1435: 1431: 1392: 1391: 1384: 1375: 1374: 1370: 1357: 1356: 1352: 1339: 1338: 1334: 1322: 1313: 1301: 1292: 1287: 1262: 1256: 1227: 1223: 1218: 1187:View/Edit Mouse 1182:View/Edit Human 1145: 1138: 1135:Location (UCSC) 1121: 1117: 1096: 1092: 1066: 1062: 1041: 1037: 1033: 1029: 942:ENSG00000083168 835: 749: 693: 689:histone binding 664:protein binding 599: 589: 588: 561: 552: 547: 543: 539: 535: 531: 527: 523: 519: 515: 501: 490: 485: 481: 477: 473: 471:mucosa of ileum 469: 465: 461: 457: 453: 439: 383: 370: 362: 352: 351: 350: 343: 323: 300:Gene location ( 282: 269: 261: 251: 250: 249: 242: 220: 197:Gene location ( 148: 135: 128: 73: 51: 17: 12: 11: 5: 2459: 2457: 2449: 2448: 2443: 2433: 2432: 2427: 2426: 2419: 2412: 2404: 2401: 2400: 2379: 2362: 2361: 2359: 2358: 2352: 2345: 2343: 2337: 2330: 2327: 2324: 2323: 2320: 2318: 2317: 2310: 2303: 2295: 2288: 2287: 2244: 2201: 2166: 2123: 2088: 2045: 2002: 1959: 1946:10.1038/ng1285 1924: 1881: 1846: 1793: 1758: 1715: 1680: 1643: 1623:(9): 3127–33. 1608: 1571: 1525: 1523: 1520: 1517: 1516: 1504: 1490: 1449: 1440: 1429: 1382: 1368: 1350: 1332: 1311: 1289: 1288: 1286: 1283: 1258:Main article: 1255: 1252: 1225: 1221: 1217: 1214: 1194: 1193: 1190: 1189: 1184: 1174: 1173: 1167: 1166: 1163: 1162: 1160: 1158: 1151: 1150: 1143: 1136: 1132: 1131: 1128: 1127: 1113: 1112: 1106: 1103: 1102: 1088: 1087: 1081: 1077: 1076: 1073: 1072: 1058: 1057: 1051: 1048: 1047: 1025: 1024: 1018: 1014: 1013: 1010: 1009: 1001: 1000: 994: 991: 990: 982: 981: 975: 969: 968: 965: 964: 956: 955: 949: 946: 945: 937: 936: 930: 924: 923: 920: 919: 911: 910: 904: 901: 900: 892: 891: 885: 879: 878: 873: 868: 864: 863: 853: 852: 849: 848: 837: 836: 834: 833: 828: 823: 818: 813: 808: 803: 798: 793: 788: 783: 778: 773: 768: 763: 757: 755: 751: 750: 748: 747: 742: 737: 732: 727: 722: 717: 712: 707: 701: 699: 695: 694: 692: 691: 686: 681: 676: 671: 666: 661: 656: 651: 646: 641: 636: 630: 628: 624: 623: 613: 612: 609: 608: 605: 604: 596: 595: 577: 571: 570: 567: 566: 558: 557: 554: 553: 551: 550: 546: 542: 538: 534: 533:left lung lobe 530: 529:lacrimal gland 526: 522: 518: 514: 510: 507: 506: 495: 492: 491: 489: 488: 484: 480: 476: 472: 468: 464: 460: 456: 452: 448: 445: 444: 432: 431: 423: 412: 406: 405: 402:RNA expression 394: 393: 390: 389: 381: 377: 376: 368: 365: 360: 354: 353: 344: 337: 331: 327: 326: 321: 315: 314: 306: 305: 293: 292: 289: 288: 280: 276: 275: 267: 264: 259: 253: 252: 243: 236: 230: 226: 225: 218: 212: 211: 203: 202: 190: 189: 146: 142: 141: 133: 125: 124: 120: 119: 116: 115: 112: 111: 69: 68: 60: 59: 48: 42: 41: 33: 32: 24: 23: 15: 13: 10: 9: 6: 4: 3: 2: 2458: 2447: 2444: 2442: 2439: 2438: 2436: 2425: 2420: 2418: 2413: 2411: 2406: 2405: 2399: 2397: 2393: 2389: 2385: 2380: 2377: 2373: 2368: 2355: 2349: 2344: 2340: 2334: 2329: 2325: 2316: 2311: 2309: 2304: 2302: 2297: 2296: 2293: 2284: 2280: 2275: 2270: 2266: 2262: 2259:(6): 3012–7. 2258: 2254: 2250: 2245: 2241: 2237: 2233: 2229: 2224: 2219: 2216:(3): 635–48. 2215: 2211: 2207: 2202: 2198: 2194: 2189: 2184: 2181:(4): 607–18. 2180: 2176: 2172: 2167: 2163: 2159: 2155: 2151: 2146: 2141: 2138:(4): 801–14. 2137: 2133: 2129: 2124: 2120: 2116: 2111: 2106: 2102: 2098: 2097:J. Biol. Chem 2094: 2089: 2085: 2081: 2076: 2071: 2067: 2063: 2059: 2055: 2051: 2046: 2042: 2038: 2033: 2028: 2024: 2020: 2016: 2012: 2008: 2003: 1999: 1995: 1990: 1985: 1981: 1977: 1973: 1969: 1965: 1960: 1956: 1952: 1947: 1942: 1938: 1934: 1930: 1925: 1921: 1917: 1912: 1907: 1903: 1899: 1895: 1891: 1887: 1882: 1878: 1874: 1869: 1864: 1861:(3): 259–71. 1860: 1856: 1852: 1847: 1843: 1839: 1834: 1829: 1824: 1819: 1815: 1811: 1807: 1803: 1799: 1794: 1790: 1786: 1781: 1776: 1772: 1768: 1764: 1759: 1755: 1751: 1746: 1741: 1737: 1733: 1729: 1725: 1721: 1716: 1712: 1708: 1703: 1698: 1694: 1690: 1686: 1681: 1677: 1673: 1669: 1665: 1661: 1657: 1654:(2): 138–44. 1653: 1649: 1644: 1640: 1636: 1631: 1626: 1622: 1618: 1614: 1609: 1605: 1601: 1597: 1593: 1589: 1585: 1581: 1577: 1572: 1568: 1564: 1560: 1556: 1552: 1548: 1544: 1540: 1536: 1532: 1527: 1526: 1521: 1514: 1508: 1505: 1500: 1494: 1491: 1486: 1482: 1477: 1472: 1468: 1464: 1460: 1453: 1450: 1444: 1441: 1438: 1433: 1430: 1425: 1421: 1417: 1413: 1409: 1405: 1401: 1397: 1389: 1387: 1383: 1378: 1372: 1369: 1364: 1360: 1354: 1351: 1346: 1342: 1336: 1333: 1329: 1325: 1320: 1318: 1316: 1312: 1308: 1304: 1299: 1297: 1295: 1291: 1284: 1282: 1279: 1275: 1271: 1267: 1261: 1253: 1251: 1249: 1246: 1245:hematopoietic 1242: 1238: 1234: 1230: 1215: 1213: 1211: 1208: 1204: 1200: 1188: 1183: 1179: 1175: 1172: 1168: 1161: 1159: 1156: 1152: 1148: 1144: 1141: 1137: 1133: 1126: 1124: 1120: 1114: 1110: 1107: 1101: 1099: 1095: 1089: 1085: 1082: 1078: 1071: 1069: 1065: 1059: 1055: 1052: 1046: 1044: 1040: 1036: 1032: 1026: 1022: 1019: 1017:RefSeq (mRNA) 1015: 1008: 1007: 1002: 998: 995: 989: 988: 983: 979: 976: 974: 970: 963: 962: 957: 953: 950: 944: 943: 938: 934: 931: 929: 925: 918: 917: 912: 908: 905: 899: 898: 893: 889: 886: 884: 880: 877: 874: 872: 869: 865: 862: 858: 854: 847: 843: 838: 832: 829: 827: 824: 822: 819: 817: 814: 812: 809: 807: 804: 802: 799: 797: 794: 792: 789: 787: 784: 782: 779: 777: 774: 772: 769: 767: 764: 762: 759: 758: 756: 753: 752: 746: 743: 741: 740:nuclear speck 738: 736: 733: 731: 728: 726: 723: 721: 718: 716: 713: 711: 708: 706: 703: 702: 700: 697: 696: 690: 687: 685: 682: 680: 677: 675: 672: 670: 667: 665: 662: 660: 657: 655: 652: 650: 647: 645: 642: 640: 637: 635: 632: 631: 629: 626: 625: 622: 621:Gene ontology 618: 614: 602: 597: 593: 586: 581: 578: 576: 572: 564: 559: 548: 544: 540: 536: 532: 528: 524: 520: 516: 513:Gonadal ridge 512: 511: 508: 504: 499: 496: 486: 482: 478: 474: 470: 467:skin of thigh 466: 462: 458: 454: 450: 449: 446: 442: 437: 434: 433: 430: 428: 424: 422: 421: 417: 416: 413: 411: 407: 403: 399: 395: 387: 382: 378: 374: 369: 359: 355: 348: 341: 335: 328: 320: 316: 312: 307: 303: 298: 294: 286: 281: 277: 273: 268: 258: 254: 247: 240: 234: 227: 223: 217: 213: 209: 204: 200: 195: 191: 187: 183: 179: 175: 171: 167: 163: 159: 155: 151: 143: 138: 131: 126: 121: 110: 108: 104: 100: 96: 92: 88: 84: 80: 76: 70: 65: 62: 61: 57: 54: 47: 43: 38: 34: 30: 25: 20: 2396:expanding it 2388:chromosome 8 2381: 2366: 2353: 2338: 2256: 2252: 2213: 2209: 2178: 2174: 2135: 2131: 2100: 2096: 2060:(1): 55–65. 2057: 2053: 2014: 2010: 1971: 1967: 1936: 1932: 1893: 1889: 1858: 1854: 1805: 1801: 1770: 1766: 1727: 1723: 1695:(3): 404–9. 1692: 1688: 1651: 1647: 1620: 1616: 1582:(1): 33–41. 1579: 1575: 1534: 1530: 1507: 1493: 1466: 1462: 1452: 1443: 1437:- KAT6A NCBI 1432: 1402:(1): 33–41. 1399: 1395: 1371: 1362: 1353: 1344: 1335: 1263: 1219: 1206: 1202: 1198: 1197: 1123:NP_001351378 1119:NP_001074618 1116: 1094:NP_001292807 1091: 1068:NM_001364449 1064:NM_001081149 1061: 1039:NM_001305878 1035:NM_001099413 1031:NM_001099412 1028: 1004: 985: 959: 940: 914: 895: 875: 870: 545:ciliary body 541:vas deferens 425: 418: 145:External IDs 72: 2321:PDB gallery 1939:(1): 40–5. 1855:Cancer Cell 1229:zinc finger 725:nucleoplasm 639:DNA binding 475:skin of hip 463:skin of arm 384:23,433,275 371:23,349,551 363:8|8 A2 283:42,051,994 270:41,929,479 123:Identifiers 2435:Categories 2054:Genome Res 1933:Nat. Genet 1576:Nat. Genet 1396:Nat. Genet 1330:, May 2017 1309:, May 2017 1285:References 1248:stem cells 710:nucleosome 429:(ortholog) 166:HomoloGene 2386:on human 2175:Mol. Cell 1604:205342752 1424:205342752 1237:chromatin 1098:NP_006757 1043:NM_006766 861:Orthologs 730:nucleolus 174:GeneCards 2283:17182677 2253:J. Virol 2232:17081983 2197:16916647 2162:13709685 2154:16713569 2119:16613851 2084:16344560 2041:16096645 1998:15657427 1955:14702039 1920:12771199 1877:12676584 1842:12477932 1789:11965546 1767:Oncogene 1754:11742995 1711:11313971 1689:Oncogene 1676:12096923 1668:10824998 1485:17694082 1463:Oncogene 1326:– 1305:– 1274:nonsense 1270:missense 1171:Wikidata 840:Sources: 705:PML body 2274:1865993 2240:7827573 2075:1356129 2032:1201351 1810:Bibcode 1639:9558366 1596:8782817 1559:8849440 1539:Bibcode 1531:Science 1416:8782817 1328:Ensembl 1307:Ensembl 1239:-bound 1231:and an 973:UniProt 928:Ensembl 867:Species 846:QuickGO 735:cytosol 720:nucleus 404:pattern 262:8p11.21 162:2442415 130:Aliases 2281:  2271:  2238:  2230:  2195:  2160:  2152:  2117:  2082:  2072:  2039:  2029:  2011:EMBO J 1996:  1989:544007 1986:  1953:  1918:  1911:156734 1908:  1875:  1840:  1833:139241 1830:  1787:  1752:  1745:125775 1742:  1724:EMBO J 1709:  1674:  1666:  1637:  1602:  1594:  1565:  1557:  1483:  1422:  1414:  1276:, and 1157:search 1155:PubMed 1006:Q8BZ21 987:Q92794 916:244349 883:Entrez 575:BioGPS 483:cardia 451:nipple 154:601408 2390:is a 2236:S2CID 2158:S2CID 1672:S2CID 1617:Blood 1600:S2CID 1567:22619 1563:S2CID 1420:S2CID 1207:KAT6A 1203:KAT6A 876:Mouse 871:Human 842:Amigo 549:blood 521:molar 487:vulva 427:Mouse 420:Human 367:Start 302:Mouse 266:Start 199:Human 178:KAT6A 137:KAT6A 22:KAT6A 2392:stub 2384:gene 2354:2ozu 2339:1m36 2279:PMID 2228:PMID 2210:Cell 2193:PMID 2150:PMID 2132:Cell 2115:PMID 2080:PMID 2037:PMID 1994:PMID 1951:PMID 1916:PMID 1873:PMID 1838:PMID 1785:PMID 1750:PMID 1707:PMID 1664:PMID 1635:PMID 1592:PMID 1555:PMID 1481:PMID 1412:PMID 1210:gene 897:7994 410:Bgee 358:Band 319:Chr. 257:Band 216:Chr. 170:4924 150:OMIM 107:4LLB 103:4LKA 99:4LK9 95:4LJN 91:3V43 87:2RC4 83:2OZU 79:2LN0 75:1M36 56:RCSB 53:PDBe 2269:PMC 2261:doi 2218:doi 2214:127 2183:doi 2140:doi 2136:125 2105:doi 2101:281 2070:PMC 2062:doi 2027:PMC 2019:doi 1984:PMC 1976:doi 1941:doi 1906:PMC 1898:doi 1863:doi 1828:PMC 1818:doi 1775:doi 1740:PMC 1732:doi 1697:doi 1656:doi 1625:doi 1584:doi 1547:doi 1535:274 1471:doi 1404:doi 380:End 279:End 182:OMA 158:MGI 46:PDB 2437:: 2277:. 2267:. 2257:81 2255:. 2251:. 2234:. 2226:. 2212:. 2208:. 2191:. 2179:23 2177:. 2173:. 2156:. 2148:. 2134:. 2130:. 2113:. 2099:. 2095:. 2078:. 2068:. 2058:16 2056:. 2052:. 2035:. 2025:. 2015:24 2013:. 2009:. 1992:. 1982:. 1972:25 1970:. 1966:. 1949:. 1937:36 1935:. 1931:. 1914:. 1904:. 1894:31 1892:. 1888:. 1871:. 1857:. 1853:. 1836:. 1826:. 1816:. 1806:99 1804:. 1800:. 1783:. 1771:21 1769:. 1765:. 1748:. 1738:. 1728:20 1726:. 1722:. 1705:. 1693:20 1691:. 1687:. 1670:. 1662:. 1652:28 1650:. 1633:. 1621:91 1619:. 1615:. 1598:. 1590:. 1580:14 1578:. 1561:. 1553:. 1545:. 1533:. 1479:. 1467:26 1465:. 1461:. 1418:. 1410:. 1400:14 1398:. 1385:^ 1361:. 1343:. 1314:^ 1293:^ 1272:, 1250:. 1224:HC 844:/ 386:bp 373:bp 285:bp 272:bp 180:; 176:: 172:; 168:: 164:; 160:: 156:; 152:: 105:, 101:, 97:, 93:, 89:, 85:, 81:, 77:, 2423:e 2416:t 2409:v 2398:. 2314:e 2307:t 2300:v 2285:. 2263:: 2242:. 2220:: 2199:. 2185:: 2164:. 2142:: 2121:. 2107:: 2086:. 2064:: 2043:. 2021:: 2000:. 1978:: 1957:. 1943:: 1922:. 1900:: 1879:. 1865:: 1859:3 1844:. 1820:: 1812:: 1791:. 1777:: 1756:. 1734:: 1713:. 1699:: 1678:. 1658:: 1641:. 1627:: 1606:. 1586:: 1569:. 1549:: 1541:: 1501:. 1487:. 1473:: 1426:. 1406:: 1379:. 1365:. 1347:. 1226:3 1222:2 1201:( 304:) 201:) 184::

Index


PDB
PDBe
RCSB
1M36
2LN0
2OZU
2RC4
3V43
4LJN
4LK9
4LKA
4LLB
Aliases
KAT6A
OMIM
601408
MGI
2442415
HomoloGene
4924
GeneCards
KAT6A
OMA
KAT6A - orthologs
Human
Chromosome 8 (human)
Chr.
Chromosome 8 (human)
Chromosome 8 (human)

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