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hospitalization is not introduced. Handcuffs may be necessary, but intellectuals do not enter sanatoriums with excuses. The law should be powerful." On
October 2, 1952. "On on the testimony last year, I did not have enough time for preparation. There was no time. The people I want to hospitalize with power are exceptionally violent patients. I am afraid of familial infection."
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283:, the original Mitsuda reaction. He reported it at the 3rd International Leprosy Congress in 1923 but received little attention. Mitsuda stored the necessary materials in a refrigerator and tried to persuade many doctors who came under him to study them, and finally found Fumio Hayashi. The Mitsuda Test was at last completed by Fumio Hayashi.
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Kensuke
Mitsuda was also known as a strict segregationalist and in 1951 he testified at the Japanese Upper House that all Hansen's disease patients be hospitalized. Although the value of Promin was being established later, he did not change his principle and contributed to the 1953 leprosy prevention
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His testimony on
November 8, 1951. "The statistics of the Ministry of Welfare say that 2000 patients are not in the sanatoriums, but there may be more patients. The patients out of the sanatoriums should be hospitalized, and many patients refuse our requests. Familial infection continues if forced
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in order to cope with the children born of patients. Originally, it was due to difficulties to bring up the children within the hospital, and later, the worsening of leprosy in pregnancy. The
Interior Ministry was consulted, but did not give any response. Later he was bitterly
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test is his most important achievement. It proved very useful in the classification of leprosy. However, the original idea was to distinguish leprosy patients and persons with normal blood, and he invented a skin test using the killed
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for two years. In 1897, he worked at the Tokyo
Metropolitan Yoikuen Hospital where he met leprosy patients. In 1899, he isolated leprosy patients within the hospital and created a ward "Kaishun Ward", named after Kaishun Hospital of
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The importance of the
Mitsuda (lepromin) reaction may be confirmed by the fact that it is the axis of the Ridley-Jopling classification of leprosy. Four papers related to the Mitsuda reaction in the Year Book of Dermatology
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policy of Japan. He was given the Order of
Cultural Merits (1951) and Damien-Dutton Award (1961). He has been the cause of admiration from one side, and the target of criticism from the other.
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In 1909, he became the chief doctor at the newly established Tama
Zenshoen Hospital and then in 1914 he became the director of the hospital. He made a world trip to study leprosy abroad.
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Comparison in leprosy patients of
Fernandez and Mitsuda reactions using human and armadillo antigens: double-blind study. Millar JW, Gannon C, Chan CSP. Int J Lepr 43:226-233, 1975.
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Histologic study of the
Mitsuda reaction in patients with lepromatous leprosy and its prognostic value in bacteriologically negative cases. Oscar Reyes. Med cutanea 3:1139,1968.
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city. He went up to Tokyo in 1894 and studied medicine at a doctor's office and passed the First Stage Doctors' Practice Examination in 1895. Later he studied at a
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Lepromin skin testing in the classification of Hansen's disease in the United States. Krotoski WA, et al. Am J Med Scie 305:18-24,1993.
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On the value of skin reaction with emulsion of leproma, Jpn J Dermatol Urol 19,8,1919 (The first paper leading to the Mitsuda reaction)
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The Mitsuda lepromin reaction in long-term treated lepromatous leprosy. Waters MFR, Ridley DS, Lucas SB. Lepr Rev 61,347-352,1990.
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Mitsuda K: Atlas of Leprosy 1952 A study of 150 autopsies on cases of leprosy. Mitsuda K, Ogawa M. Int J Leprosy. 5,1,1937
260:. The number of autopsies he conducted is the largest in the world, when the cases performed later were added.
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Sato S Outlook of The Third International Leprosy Congress, Papers on Leprosy (2) by Kensuke Mitsuda, 1950
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Mitsuda K The significance of skin tests using leprosy nodule extracts. Jpn J Dermatol Urologγ19, 8, 1919.
42:(1914β1931) and the National Sanatorium Nagashima Aiseien (1931β1957). He had been at the frontier of
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On the therapeutic value of Gynocardia ( Chaulmoogra) oil in leprosy, Jpn J Dermatol Urol 12,12,1912
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On the Langhans giant cell in leprosy and the stellate body in nodular leprosy, Int J Lepr 3,3,1935
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Pathological changes in the central nervous system in leprosy, Shinkeigaku Zasshi, 6,6 and 7, 1906
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Pathological changes in the peripheral nerves and blood vessels, Tokyo Igakkai Zasshi 14,15,1900
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As a leprologist, he was essentially a pathologist. He first discovered the coexistence of
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On the lymphnode affected with leprosy and tuberculosis, Tokyo Igakkai Zasshi 15,9,1901
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Saisei Gakusha. He passed the final qualification examination in 1896. He then studied
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On the relation between tattoo and Mycobacterium leprae, Jpn J Dermatol Urol 27,8,1927
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Pathological changes in the blood vessels and their significance, Nihon Igaku 15,1906
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Coexistence of leprosy and scabies, Nihon Kohshuuhokenkyoukai Zasshi, 10,11,1934
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Hayashi F. Mitsuda's skin reaction in leprosy Intern J Lepr 1:31-38, 1933.
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Yamamoto S. History of leprosy in Japan. University of Tokyo Press, 1993
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Pathological studies of leprosy treated with Promin, Repura 20,5,1951
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177:. Later he lectured many times on the need of public leprosy policy.
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A study of 150 autopsies on cases of leprosy, Int J Lepr 5,1,1937
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On the serum reactions in leprosy, Jpn J Dermatol Urol 11,7,1910
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The southernmore, the milder leprosy becomes, Repura 15,3,1944
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On the leprosy of internal organs, Nihon Rengo Igakkaishi 1902
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Treatment of leprosy with cepharanthin, Nihon Igaku 3389,1944
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in 1876 and studied medicine at a private doctor's office in
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reaction, (Mitsuda reaction), Segregation of leprosy patients
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On the lymphadenitis leprosa, Tokyo Igakkai Zasshi, 13, 1899
205:, remote islands were considered as possible sites of
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373:On the classification of leprosy, Repura 15,2,1943
236:law, which retained the principle of segregation.
457:Mitsuda K. Asahi Shimbunsha, 1950 (In Japanese).
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288:Importance of the Mitsuda (lepromin) Reaction
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217:, and he became the first director in 1931.
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370:On alopecia leprosa, Int J Lepr 5,3,1937
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270:Although he did not regard himself an
192:National Sanatorium Nagashima Aiseien
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119:Physician, Director of Sanatoriums
32:, January 12, 1876 β May 14, 1964)
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496:20th-century Japanese physicians
491:19th-century Japanese physicians
319:Representative Papers of Mitsuda
127:Leprosy researches (pathology),
455:Kaishun Byoshitsu(Kaishun Ward)
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450:Masao Ota(Mokutaro Kinoshita)
385:Atlas of leprosy (book), 1952
326:His name Mitsuda K is omitted
486:Japanese healthcare managers
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506:University of Tokyo alumni
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197:Following the examples of
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40:Tama Zenshoen Sanatorium
511:Japanese dermatologists
274:, his discovery of the
65:Kensuke Mitsuda in 1956
182:Tama Zenshoen Hospital
501:Japanese pathologists
471:Japanese leprologists
150:Yamaguchi Prefecture
85:Yamaguchi Prefecture
38:and director of the
166:University of Tokyo
215:Okayama Prefecture
256:and leprosy in a
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175:public hospitals
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81:January 12, 1876
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53:Kensuke Mitsuda
34:was a Japanese
29:Mitsuda Kensuke
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17:Kensuke Mitsuda
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158:Private school
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124:Known for
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116:Occupation(s)
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272:immunologist
254:tuberculosis
101:(1964-05-14)
99:May 14, 1964
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481:1964 deaths
476:1876 births
232:criticized.
227:He started
207:sanatoriums
203:Philippines
108:Nationality
36:leprologist
465:Categories
444:References
265:Immunology
258:lymph node
222:Criticisms
211:Inland Sea
143:Early life
77:1876-01-12
247:Pathology
229:vasectomy
162:pathology
154:Yamaguchi
296:Lepromin
276:lepromin
201:and the
171:Kumamoto
129:Lepromin
111:Japanese
302:follow.
281:bacilli
164:at the
44:leprosy
199:Hawaii
390:Notes
89:Japan
23:ε
η° ε₯θΌ
138:Life
96:Died
71:Born
213:of
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