362:"mosaic" of ancestry in Professor Gates' and his father's genomes, tracing their ancestry to Africa, Europe, and beyond. By comparing the two genomes to each other, they revealed the shared genetic heritage of a father and son, including aspects of their health risks and strengths. Further, by documenting the parts of their genomes that the two men did not share, Knome's analysis offered a glimpse of the genome of Professor Gates' late mother.
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The series followed
Harvard scholar Henry Louis Gates, Jr. as he used advanced genetics tools to explore the ancestral histories of 12 renowned Americans, uncovering unique stories of immigration that illuminate the American experience. On the program, Knome scientists illuminated the striking
378:. The study uncovered notable differences in Ozzy's genes that were linked to drug and alcohol response, which shed light on how the famously hard-living rocker has survived decades of drug abuse. Several major news outlets including CNN and ABC picked up the story.
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and workflow bottlenecks that typically hinder whole genome interpretation. The company's core technology, kGAP, was developed in 2009 and served as the foundation for a number of Knome's products and services including the knoSYS® platform.
337:, "Cracking Your Genetic Code". In the show, Knome helped describe how the interpretation of human genomes is helping to solve medical mysteries and revolutionize personal healthcare.
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Provides labs with a scalable, production-grade informatics system for the analysis, annotation, and interpretation of human next-gen sequence data (genome, exome, targeted gene).
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based on the recognition that the rapidly falling price of whole genome sequencing would create substantial market need for whole genome interpretation technologies and services.
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Knome developed technologies that automated many of the manual tasks involved in interpreting whole human genomes. These technologies were designed to address the
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Research services include project-driven curation, sophisticated informatics, and in-depth interpretation by Knome's team of experienced geneticists.
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featured the knoSYS: "a powerful computer packed with software has arrived to interpret sequences privately within the walls of a lab".
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2008 – Knome interpreted the genome of the third named person to be sequenced—Dan
Stoicescu (who followed
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Acquired by Tute
Genomics, Inc. in 2015 (which later becomes a subsidiary of PierianDX, Inc. in 2016)
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539:"Days after scrapping crowdfunding campaign, Tute accepts PierianDx buyout bid | FierceBiotech"
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For academic, pharmaceutical, and medical researchers, Knome offered:
521:"Johns Hopkins Taps Knome to Analyze Data for 1K Genome Asthma Study"
600:""Faces of America: Know Thyself" credits - Faces of America - PBS"
499:"Knome Assists Canadian Team Identify Parkinson's Disease Gene"
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663:"Genetic Mutations Let Ozzy Osbourne Party Hard - ABC News"
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to identify the sixth known inherited gene defect causing
422:"Informatics and Genomic Interpretation System - knoSYS®"
302:(which later becomes a subsidiary of PierianDX in 2016).
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In
September 2011, Knome was featured in the four-part
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In March 2012, Knome appeared on a special episode of
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2010 – Knome successfully assisted researchers at the
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2012 – Knome was selected as a technology partner by
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451:"Human Genome Research Services - knomeDISCOVERY"
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618:"Ozzy and Sharon Osbourne: Who's healthier?"
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692:Companies based in Cambridge, Massachusetts
162:Sundar Subramaniam (founder & Chairman)
295:to analyze 1,000 genomes for asthma study.
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16:Former human genome interpretation company
640:"DNA Day: Meet the Osbournes' geneticist"
73:Learn how and when to remove this message
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564:"Genomic Analysis, the Office Edition"
34:contains content that is written like
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582:"NOVA - Cracking Your Genetic Code"
562:Eisenberg, Anne (2 February 2013).
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481:"Gene Map Becomes a Luxury Item"
293:Johns Hopkins School of Medicine
189:interpretation company based in
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251:2007 – Knome was co-founded by
195:interpretation of human genomes
397:"Tute Genomics Acquires Knome"
282:University of British Columbia
269:2009 – Knome launched kGAP, a
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646:. 2011-04-15. Archived from
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479:Harmon, Amy (4 March 2008).
176:Human genome interpretation
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191:Cambridge, Massachusetts
132:Cambridge, Massachusetts
661:ABC News (2010-11-02).
359:Henry Louis Gates, Jr.
315:In February 2013, the
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650:on February 10, 2017.
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222:Products and services
159:Jorge Conde (founder)
55:neutral point of view
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401:www.prnewswire.com
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307:In the media
264:Craig Venter
260:James Watson
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187:human genome
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127:Headquarters
91:Company type
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45:by removing
41:Please help
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275:informatics
215:informatics
183:Knome, Inc.
86:Knome, Inc.
681:Categories
548:2018-12-25
465:2014-08-01
436:2014-08-01
407:2022-07-28
383:References
209:Technology
146:Key people
43:improve it
525:GenomeWeb
667:ABC News
246:Timeline
173:Services
101:Industry
644:cnn.com
622:cnn.com
586:pbs.org
351:series
277:engine.
273:-based
199:disease
111:Founded
95:Private
185:was a
455:Knome
426:Knome
357:with
271:cloud
374:and
372:Ozzy
334:NOVA
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262:and
119:Fate
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349:PBS
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