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Lymphovascular invasion

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The predictive value and prevalence of lymphovascular invasion is strongly dependent on the type of cancer. In other words, LVI in one type of cancer may be much less important than LVI in another type of cancer.
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Lim, SB.; Yu, CS.; Jang, SJ.; Kim, TW.; Kim, JH.; Kim, JC. (Apr 2010). "Prognostic significance of lymphovascular invasion in sporadic colorectal cancer".
242:"Predictors of invasion and axillary lymph node metastasis in patients with a core biopsy diagnosis of ductal carcinoma in situ: an analysis of 255 cases" 106:, usually precedes spread to the lymph nodes that drain the tissue in which the tumour arose. Conversely, cancers with lymph node spread (known as a 149: 338:
Fang WL, Chang SC, Lin JK, Wang HS, Yang SH, Jiang JK, Chen WC, Lin TC (2005). "Metastatic potential in T1 and T2 colorectal cancer".
443:"The role of lymphovascular invasion as a prognostic factor in patients with lymph node-positive operable invasive breast cancer" 365:
Moreira LF, Kenmotsu M, Gochi A, Tanaka N, Orita K (1999). "Lymphovascular and neural invasion in low-lying rectal carcinoma".
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A clear or white fluid that travels through vessels, moves within tissues and work to keep all the parts of the body clean.
402:"Population-based study of peritumoral lymphovascular invasion and outcome among patients with operable breast cancer" 167:
Whether LVI is a significant prognostic factor in breast cancer is widely debated, and there is no clear consensus.
575: 154: 110:), usually have lymphovascular invasion. Lymph node metastases usually precede secondary tumours, i.e. distant 133:
Generally speaking, it is associated with lymph node metastases which themselves are predictive of a poorer
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The body's network of blood vessels. When cancer spreads to lymph and vascular system, it is thus termed as
141:) proven lymph node metastases, LVI may have less prognostic significance or no prognostic significance. 107: 204: 182: 176: 216: 117:
The absence of LVI in the context of proven lymph node metastasis is usually thought to be due to
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Ejlertsen B, Jensen MB, Rank F, Rasmussen BB, Christiansen P, Kroman N, et al. (May 2009).
580: 544: 509: 472: 423: 382: 347: 320: 263: 198: 61: 291:"Prognostic value of lymphangiogenesis and lymphovascular invasion in invasive breast cancer" 17: 536: 499: 462: 454: 413: 374: 310: 302: 253: 185:, LVI is an independent predictor of a poorer prognosis that has more predictive power than 73: 38: 289:
Schoppmann SF, Bayer G, Aumayr K, Taucher S, Geleff S, Rudas M, et al. (August 2004).
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Cheng, L.; Montironi, R.; Davidson, DD.; Lopez-Beltran, A. (Jun 2009).
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Song YJ, Shin SH, Cho JS, Park MH, Yoon JH, Jegal YJ (September 2011).
492:"Staging and reporting of urothelial carcinoma of the urinary bladder" 65: 148: 29: 37:
showing lymphovascular invasion (top of image) in a case of
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Penetration of a cancer into the blood and/or lymph vessels
8: 503: 466: 417: 314: 257: 232: 102:Lymphovascular invasion, especially in 240:Han JS, Molberg KH, Sarode V (2011). 7: 307:10.1097/01.sla.0000133355.48672.22 25: 379:10.1046/j.1525-1500.1999.09908.x 259:10.1111/j.1524-4741.2011.01069.x 1: 207:, LVI of a poorer prognosis. 58:lymphovascular space invasion 18:Lymphovascular space invasion 541:10.1007/DCR.0b013e3181cf8ae5 597: 196: 174: 160: 459:10.4048/jbc.2011.14.3.198 155:invasive ductal carcinoma 505:10.1038/modpathol.2009.1 93:Lymphovascular Invasion. 125:Prognostic significance 50:Lymphovascular invasion 498:. 22 Suppl 2: S70–95. 340:Hepatogastroenterology 158: 153:Lymphatic invasion by 46: 152: 137:. In the context of ( 108:lymph node metastases 33: 406:J. Natl. Cancer Inst 205:colorectal carcinoma 183:urothelial carcinoma 177:Urothelial carcinoma 171:Urothelial carcinoma 419:10.1093/jnci/djp090 367:Cancer Detect. Prev 217:Perineural invasion 246:The Breast Journal 159: 47: 199:Colorectal cancer 193:Colorectal cancer 16:(Redirected from 588: 576:Cancer pathology 561: 560: 529:Dis Colon Rectum 524: 518: 517: 507: 487: 481: 480: 470: 438: 432: 431: 421: 397: 391: 390: 362: 356: 355: 335: 329: 328: 318: 286: 280: 279: 261: 237: 39:laryngeal cancer 21: 596: 595: 591: 590: 589: 587: 586: 585: 566: 565: 564: 526: 525: 521: 489: 488: 484: 447:J Breast Cancer 440: 439: 435: 399: 398: 394: 364: 363: 359: 346:(66): 1688–91. 337: 336: 332: 288: 287: 283: 239: 238: 234: 230: 213: 201: 195: 179: 173: 165: 147: 127: 100: 82: 28: 23: 22: 15: 12: 11: 5: 594: 592: 584: 583: 578: 568: 567: 563: 562: 519: 482: 453:(3): 198–203. 433: 412:(10): 729–35. 392: 357: 330: 281: 231: 229: 226: 225: 224: 219: 212: 209: 197:Main article: 194: 191: 175:Main article: 172: 169: 161:Main article: 157:of the breast. 146: 143: 139:histologically 126: 123: 119:sampling error 99: 96: 81: 78: 26: 24: 14: 13: 10: 9: 6: 4: 3: 2: 593: 582: 579: 577: 574: 573: 571: 558: 554: 550: 546: 542: 538: 535:(4): 377–84. 534: 530: 523: 520: 515: 511: 506: 501: 497: 493: 486: 483: 478: 474: 469: 464: 460: 456: 452: 448: 444: 437: 434: 429: 425: 420: 415: 411: 407: 403: 396: 393: 388: 384: 380: 376: 372: 368: 361: 358: 353: 349: 345: 341: 334: 331: 326: 322: 317: 312: 308: 304: 301:(2): 306–12. 300: 296: 292: 285: 282: 277: 273: 269: 265: 260: 255: 251: 247: 243: 236: 233: 227: 223: 220: 218: 215: 214: 210: 208: 206: 200: 192: 190: 188: 184: 178: 170: 168: 164: 163:Breast cancer 156: 151: 145:Breast cancer 144: 142: 140: 136: 131: 124: 122: 120: 115: 113: 109: 105: 97: 95: 94: 90: 86: 79: 77: 75: 71: 70:blood vessels 67: 63: 59: 55: 51: 44: 43:H&E stain 40: 36: 32: 19: 532: 528: 522: 495: 485: 450: 446: 436: 409: 405: 395: 373:(2): 123–8. 370: 366: 360: 343: 339: 333: 298: 294: 284: 252:(3): 223–9. 249: 245: 235: 203:In sporadic 202: 187:tumour stage 180: 166: 132: 128: 116: 101: 92: 88: 84: 83: 57: 53: 49: 48: 80:Terminology 570:Categories 496:Mod Pathol 228:References 222:Malignancy 112:metastases 104:carcinomas 74:lymphatics 35:Micrograph 295:Ann. Surg 135:prognosis 98:Pathology 89:Vascular: 60:) is the 581:Oncology 557:23220174 549:20305435 514:19494855 477:22031801 428:19436035 387:10101593 352:16334758 325:15273556 268:21545433 211:See also 62:invasion 468:3200515 316:1356408 276:9775260 72:and/or 68:to the 555:  547:  512:  475:  465:  426:  385:  350:  323:  313:  274:  266:  85:Lymph: 66:cancer 553:S2CID 272:S2CID 64:of a 545:PMID 510:PMID 473:PMID 424:PMID 383:PMID 348:PMID 321:PMID 264:PMID 537:doi 500:doi 463:PMC 455:doi 414:doi 410:101 375:doi 311:PMC 303:doi 299:240 254:doi 181:In 56:or 54:LVI 572:: 551:. 543:. 533:53 531:. 508:. 494:. 471:. 461:. 451:14 449:. 445:. 422:. 408:. 404:. 381:. 371:23 369:. 344:52 342:. 319:. 309:. 297:. 293:. 270:. 262:. 250:17 248:. 244:. 189:. 121:. 114:. 76:. 41:. 559:. 539:: 516:. 502:: 479:. 457:: 430:. 416:: 389:. 377:: 354:. 327:. 305:: 278:. 256:: 52:( 45:. 20:)

Index

Lymphovascular space invasion

Micrograph
laryngeal cancer
H&E stain
invasion
cancer
blood vessels
lymphatics
carcinomas
lymph node metastases
metastases
sampling error
prognosis
histologically

invasive ductal carcinoma
Breast cancer
Urothelial carcinoma
urothelial carcinoma
tumour stage
Colorectal cancer
colorectal carcinoma
Perineural invasion
Malignancy
"Predictors of invasion and axillary lymph node metastasis in patients with a core biopsy diagnosis of ductal carcinoma in situ: an analysis of 255 cases"
doi
10.1111/j.1524-4741.2011.01069.x
PMID
21545433

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