184:
553:
33:
65:
281:
protein is approximately three times smaller (125 kD) than its human counterpart. Furthermore, analyses revealed that LiBRCA2 possesses key features of the BRCA2 family. The smaller size of the
498:
Hide, Mallorie; Michel, Gregory; Legueult, Kevin; Pin, Raphaelle; Leonard, Susana; Simon, Loïc; Bañuls, Anne-Laure; Delaunay, Pascal; Marty, Pierre; Pomares, Christelle (2024).
1148:
285:
BRCA2 DNA repair protein has been exploited to better understand its function in homologous recombination and its interaction with the LiRAD51 recombinase.
783:
1135:
183:
1199:
960:
776:
695:
Genois MM, Mukherjee A, Ubeda JM, Buisson R, Paquet E, Roy G, Plourde M, Coulombe Y, Ouellette M, Masson JY (August 2012).
1189:
619:
Le Blancq SM, Peters W (1986). "Leishmania in the Old World: 4. The distribution of L. donovani sensu lato zymodemes".
1204:
1109:
909:
250:, and some authors believe that these two species are so close as to actually be subspecies of each other; however,
64:
769:
1153:
1194:
755:
1100:
903:
895:
840:
217:
552:
1062:
929:
201:
1019:
884:
566:
Alexander, Bruce; Lopes de
Carvalho, Renata; McCallum, Hamish; Pereira, Marcos Horácio (December 2002).
234:
139:
1122:
1033:
374:
656:"Analysis of ribosomal DNA internal transcribed spacer sequences of the Leishmania donovani complex"
918:
880:
799:
246:
888:
834:
164:
59:
761:
751:
1161:
954:
848:
792:
730:
677:
636:
601:
541:
523:
480:
441:
402:
336:
229:
1166:
876:
720:
712:
667:
628:
591:
583:
531:
515:
472:
433:
392:
382:
326:
318:
1114:
1039:
994:
825:
816:
255:
155:
106:
254:
can easily distinguish between the two groups despite no difference in morphology in the
536:
499:
378:
1025:
1010:
945:
854:
725:
696:
596:
567:
397:
358:
331:
306:
96:
437:
1183:
866:
807:
632:
251:
209:
205:
32:
672:
655:
476:
1094:
697:"Interactions between BRCA2 and RAD51 for promoting homologous recombination in
48:
1085:
519:
322:
999:
985:
116:
86:
44:
527:
976:
387:
76:
734:
681:
605:
587:
545:
484:
445:
406:
340:
640:
1079:
796:
716:
504:
infection in dogs and dog owners in an endemic area in southeast France"
1140:
459:
BenSaid M, Guerbouj S, Saghrouni F, et al. (2006). "Occurrence of
220:, which is normally caused by specific lineages (or zymodemes). Wild
1056:
420:
Maurício IL, Stothard JR, Miles MA (May 2000). "The strange case of
465:
Transactions of the Royal
Society of Tropical Medicine and Hygiene
278:
238:
serves as the primary vector for the transmission of the disease.
221:
182:
1127:
654:
Kuhls K, Mauricio IL, Pratlong F, Presber W, Schönian G (2005).
1060:
765:
572:)in the Epidemiology of Urban Visceral Leishmaniasis in Brazil"
274:
Comparative bioinformatic analyses showed that the size of the
225:
52:
1069:
1009:
984:
975:
944:
865:
824:
815:
806:
307:"Cutaneous Leishmaniasis in North Africa: a review"
367:Proceedings of the National Academy of Sciences
359:"Evolutionary and geographical history of the
777:
463:cutaneous leishmaniasis in central Tunisia".
8:
363:complex with a revision of current taxonomy"
1057:
981:
821:
812:
784:
770:
762:
31:
20:
754:at the U.S. National Library of Medicine
724:
671:
595:
535:
396:
386:
330:
187:Cutaneous leishmaniasis in North Africa;
294:
352:
350:
300:
298:
270:Model system for studies of DNA repair
232:of this organism. The sandfly species
7:
200:is the causative agent of infantile
961:Primary amoebic meningoencephalitis
258:. Some isolates formerly labelled
14:
305:Aoun, K.; Bouratbine, A. (2014).
216:. It is also an unusual cause of
551:
63:
51:smear from a naturally infected
568:"Role of the Domestic Chicken (
1:
621:Trans. R. Soc. Trop. Med. Hyg
438:10.1016/S0169-4758(00)01637-9
426:Parasitol. Today (Regul. Ed.)
357:Lukeš J, et al. (2007).
673:10.1016/j.micinf.2005.04.009
633:10.1016/0035-9203(86)90320-2
576:Emerging Infectious Diseases
477:10.1016/j.trstmh.2005.08.012
16:Species of parasitic protist
910:Mucocutaneous leishmaniasis
212:, where it has been called
191:infected areas are in green
1221:
1200:Protists described in 1908
170:
163:
145:
138:
60:Scientific classification
58:
39:
30:
23:
756:Medical Subject Headings
520:10.1051/parasite/2024019
323:10.1051/parasite/2014014
896:Cutaneous leishmaniasis
841:African trypanosomiasis
388:10.1073/pnas.0703678104
218:cutaneous leishmaniasis
930:Visceral leishmaniasis
588:10.3201/eid0812.010485
244:is closely related to
202:visceral leishmaniasis
192:
1020:Trichomonas vaginalis
252:phylogenetic analyses
235:Lutzomyia longipalpis
186:
1034:Dientamoeba fragilis
1190:Parasitic excavates
1115:Leishmania_infantum
1101:Leishmania infantum
1071:Leishmania infantum
752:Leishmania+infantum
699:Leishmania infantum
502:Leishmania infantum
461:Leishmania infantum
379:2007PNAS..104.9375L
361:Leishmania donovani
247:Leishmania donovani
242:Leishmania infantum
197:Leishmania infantum
189:Leishmania infantum
149:Leishmania infantum
42:Leishmania infantum
25:Leishmania infantum
1205:Euglenozoa species
717:10.1093/nar/gks306
666:(11–12): 1224–34.
422:Leishmania chagasi
214:Leishmania chagasi
193:
174:Leishmania chagasi
1177:
1176:
1162:Open Tree of Life
1063:Taxon identifiers
1054:
1053:
1050:
1049:
971:
970:
955:Naegleria fowleri
940:
939:
793:Parasitic disease
705:Nucleic Acids Res
230:natural reservoir
181:
180:
1212:
1170:
1169:
1157:
1156:
1144:
1143:
1131:
1130:
1118:
1117:
1105:
1104:
1103:
1090:
1089:
1088:
1058:
982:
926:
892:
877:Leishmania major
822:
813:
786:
779:
772:
763:
739:
738:
728:
692:
686:
685:
675:
651:
645:
644:
616:
610:
609:
599:
563:
557:
556:
555:
549:
539:
495:
489:
488:
456:
450:
449:
417:
411:
410:
400:
390:
354:
345:
344:
334:
302:
262:may be actually
151:
131:L. infantum
68:
67:
35:
21:
1220:
1219:
1215:
1214:
1213:
1211:
1210:
1209:
1195:Trypanosomatida
1180:
1179:
1178:
1173:
1165:
1160:
1152:
1147:
1139:
1134:
1126:
1121:
1113:
1108:
1099:
1098:
1093:
1084:
1083:
1078:
1065:
1055:
1046:
1040:Dientamoebiasis
1005:
995:Giardia lamblia
967:
936:
916:
904:L. braziliensis
874:
861:
826:Trypanosomiasis
817:Trypanosomatida
802:
790:
748:
743:
742:
711:(14): 6570–84.
694:
693:
689:
660:Microbes Infect
653:
652:
648:
618:
617:
613:
565:
564:
560:
550:
497:
496:
492:
458:
457:
453:
419:
418:
414:
373:(22): 9375–80.
356:
355:
348:
304:
303:
296:
291:
272:
256:species complex
159:
153:
147:
134:
107:Trypanosomatida
62:
17:
12:
11:
5:
1218:
1216:
1208:
1207:
1202:
1197:
1192:
1182:
1181:
1175:
1174:
1172:
1171:
1158:
1145:
1132:
1119:
1106:
1091:
1075:
1073:
1067:
1066:
1061:
1052:
1051:
1048:
1047:
1045:
1044:
1043:
1042:
1030:
1029:
1028:
1026:Trichomoniasis
1015:
1013:
1011:Trichomonadida
1007:
1006:
1004:
1003:
990:
988:
979:
973:
972:
969:
968:
966:
965:
964:
963:
950:
948:
946:Schizopyrenida
942:
941:
938:
937:
935:
934:
933:
932:
914:
913:
912:
900:
899:
898:
871:
869:
863:
862:
860:
859:
858:
857:
855:Chagas disease
845:
844:
843:
830:
828:
819:
810:
804:
803:
791:
789:
788:
781:
774:
766:
760:
759:
747:
746:External links
744:
741:
740:
687:
646:
611:
582:(12): 1480–5.
558:
500:"Asymptomatic
490:
451:
412:
346:
293:
292:
290:
287:
271:
268:
208:region and in
179:
178:
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28:
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15:
13:
10:
9:
6:
4:
3:
2:
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1120:
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1102:
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1087:
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1076:
1074:
1072:
1068:
1064:
1059:
1041:
1038:
1037:
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1035:
1031:
1027:
1024:
1023:
1022:
1021:
1017:
1016:
1014:
1012:
1008:
1001:
997:
996:
992:
991:
989:
987:
986:Diplomonadida
983:
980:
978:
974:
962:
959:
958:
957:
956:
952:
951:
949:
947:
943:
931:
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920:
915:
911:
908:
907:
906:
905:
901:
897:
894:
893:
891:
890:
886:
885:L. aethiopica
882:
878:
873:
872:
870:
868:
867:Leishmaniasis
864:
856:
853:
852:
851:
850:
846:
842:
839:
838:
837:
836:
832:
831:
829:
827:
823:
820:
818:
814:
811:
809:
808:Discicristata
805:
801:
798:
794:
787:
782:
780:
775:
773:
768:
767:
764:
757:
753:
750:
749:
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736:
732:
727:
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714:
710:
706:
702:
700:
691:
688:
683:
679:
674:
669:
665:
661:
657:
650:
647:
642:
638:
634:
630:
627:(3): 367–77.
626:
622:
615:
612:
607:
603:
598:
593:
589:
585:
581:
577:
573:
571:
570:Gallus gallus
562:
559:
554:
547:
543:
538:
533:
529:
525:
521:
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513:
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503:
494:
491:
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478:
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277:
269:
267:
265:
261:
257:
253:
249:
248:
243:
239:
237:
236:
231:
227:
224:and domestic
223:
219:
215:
211:
210:Latin America
207:
206:Mediterranean
203:
199:
198:
190:
185:
175:
172:
171:
169:
166:
162:
157:
152:
150:
144:
141:
140:Binomial name
137:
133:
132:
127:
124:
123:
120:
119:
115:
112:
111:
108:
105:
102:
101:
98:
97:Kinetoplastea
95:
92:
91:
88:
85:
82:
81:
78:
75:
72:
71:
66:
61:
57:
54:
50:
46:
43:
38:
34:
29:
26:
22:
19:
1070:
1032:
1018:
993:
953:
922:
917:
902:
875:
847:
833:
708:
704:
698:
690:
663:
659:
649:
624:
620:
614:
579:
575:
569:
561:
511:
507:
501:
493:
471:(6): 521–6.
468:
464:
460:
454:
432:(5): 188–9.
429:
425:
421:
415:
370:
366:
360:
314:
310:
282:
275:
273:
263:
259:
245:
241:
240:
233:
213:
196:
195:
194:
188:
173:
148:
146:
130:
129:
117:
41:
24:
18:
1095:Wikispecies
919:L. donovani
881:L. mexicana
276:L. infantum
264:L. infantum
260:L. donovani
49:bone marrow
45:amastigotes
1184:Categories
1000:Giardiasis
889:L. tropica
795:caused by
289:References
283:Leishmania
118:Leishmania
87:Euglenozoa
977:Trichozoa
835:T. brucei
528:1776-1042
125:Species:
77:Eukaryota
1128:52252663
1086:Q1950789
1080:Wikidata
923:infantum
849:T. cruzi
800:protozoa
797:Excavata
735:22505581
682:16002315
606:12498667
546:38530209
537:10964848
508:Parasite
485:16356518
446:10782075
407:17517634
341:24626301
311:Parasite
228:are the
165:Synonyms
83:Phylum:
73:Domain:
40:Several
1141:9442158
726:3413117
641:3798531
597:2738513
398:1890502
375:Bibcode
332:3952656
204:in the
156:Nicolle
113:Genus:
103:Order:
93:Class:
1167:243214
758:(MeSH)
733:
723:
680:
639:
604:
594:
544:
534:
526:
514:: 16.
483:
444:
405:
395:
339:
329:
317:: 14.
222:canids
158:, 1908
279:BRCA2
47:in a
1154:5671
1149:NCBI
1136:GBIF
731:PMID
678:PMID
637:PMID
602:PMID
542:PMID
524:ISSN
481:PMID
442:PMID
403:PMID
337:PMID
226:dogs
1123:EoL
1110:AFD
721:PMC
713:doi
668:doi
629:doi
592:PMC
584:doi
532:PMC
516:doi
473:doi
469:100
434:doi
424:".
393:PMC
383:doi
371:104
327:PMC
319:doi
53:dog
1186::
1164::
1151::
1138::
1125::
1112::
1097::
1082::
921:/
887:/
883:/
879:/
729:.
719:.
709:40
707:.
703:.
676:.
662:.
658:.
635:.
625:80
623:.
600:.
590:.
578:.
574:.
540:.
530:.
522:.
512:31
510:.
506:.
479:.
467:.
440:.
430:16
428:.
401:.
391:.
381:.
369:.
365:.
349:^
335:.
325:.
315:21
313:.
309:.
297:^
266:.
1002:)
998:(
785:e
778:t
771:v
737:.
715::
701:"
684:.
670::
664:7
643:.
631::
608:.
586::
580:8
548:.
518::
487:.
475::
448:.
436::
409:.
385::
377::
343:.
321::
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