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considered to be the three major dementias." The NINDS (2020) says that Lewy body dementia "is one of the most common causes of dementia, after
Alzheimer's disease and vascular disease." Hershey (2019) says, "DLB is the third most common of all the neurodegenerative diseases behind both Alzheimer's disease and Parkinson's disease".
221:
Dementia with Lewy bodies and
Parkinson's disease dementia have similar neuropathological features, but these features are highly variable and the conditions cannot be distinguished on pathological features alone. Generally, dementia with Lewy bodies is distinguished from Parkinson's disease dementia
297:
promote awareness and provide support that helps society, by reducing costly use of healthcare, and families with LBD, by reducing stress. These organizations, and others in
Argentina, Australia and Japan, help raise knowledge and help families with LBD become advocates to raise awareness about the
144:. The Lewy body dementias—dementia with Lewy bodies (DLB), and Parkinson's disease dementia (PDD)—are distinguished by the timing when cognitive and motor symptoms appear. The two Lewy body dementias are often considered to belong on a spectrum of Lewy body disease that includes Parkinson's disease.
206:
Despite differences in the timing of the appearance of symptoms, the two dementias "show remarkably convergent neuropathological changes at autopsy". The relationship between
Parkinson's disease dementia and dementia with Lewy bodies is unclear as of 2020, but there is likely to be genetic overlap,
150:
lists Lewy body disease in several categories: as a nervous system disease in two listings one as a basal ganglia
Parkinsonian movement disorder and the other under brain disease as a dementia; as a neurodegenerative disorder listed as a synucleinopathy; and as a neurocognitive disorder listed with
560:
Kosaka (2017) writes: "Dementia with Lewy bodies (DLB) is now well known to be the second most frequent dementia following
Alzheimer disease (AD). Of all types of dementia, AD is known to account for about 50%, DLB about 20% and vascular dementia (VD) about 15%. Thus, AD, DLB, and VD are now
376:. Sahlas said his death was "variously ascribed to Alzheimer disease, Parkinson disease, or postencephalitic parkinsonism". Based on signs in his work and letters of progressive deterioration, fluctuating cognitive decline, deterioration in visuospatial function, declining
173:
Dementia with Lewy bodies and
Parkinson's disease dementia are similar in many ways, suggesting there may be a common pathophysiological mechanism, with PDD and DLB at opposite ends of a Lewy body disease spectrum, and a shared component of protein deposits in
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are responsible for the neurodegenerative effects remains unclear, and no definitive link between Lewy bodies and neurodegenerative effects has been found. DSM-5 gives Lewy body disease as the causative subtype of DLB, and
271:
As of 2014, the Lewy body dementias were more often misdiagnosed than any other common dementia. Most people with DLB had not heard of the condition prior to diagnosis; general awareness about LBD lags well behind that of
158:
is found in
Parkinson's disease and the Lewy body dementias. The presence of Lewy bodies is a link between these disorders; the term 'diseases with Lewy bodies' therefore may be more accurate than 'Lewy body disease'.
1728:
323:, the American actor and comedian, died on August 11, 2014. Before his suicide, he had been diagnosed with Parkinson's disease, and according to his widow, Susan Schneider Williams, he experienced depression,
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284:
to find that few people, including many healthcare professionals, are knowledgeable about LBD; lack of knowledge can have significant health consequences because people with LBD have severe sensitivity to
240:
Between 5% and 25% of diagnosed dementias in older adults are due to one of the Lewy body dementias. As of 2014, the Lewy body dementias affect about 1.3 million people in the US and 140,000 in the UK.
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45:(PDD). Both are characterized by changes in thinking, movement, behavior, and mood. The two conditions have similar features and may have similar causes, and are believed to belong on a spectrum of
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343:(the term used to describe pathological findings of Lewy bodies on autopsy). Dennis Dickson, a spokesperson for the Lewy Body Dementia Association, clarified the distinction by stating that
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by the time frame in which dementia symptoms appear relative to parkinsonian symptoms and is diagnosed when cognitive symptoms begin before or at the same time as
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and refers to the underlying disease process. According to
Dickson, "Lewy bodies are generally limited in distribution" in early Parkinson's disease, while in
2033:
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359:, professor and researcher of Lewy body dementias, commented that Williams' symptoms and autopsy findings were explained by dementia with Lewy bodies.
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1980:
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as the causative subtype of
Parkinson's disease dementia. Dementia with Lewy bodies is marked by the presence of Lewy bodies primarily in the
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1957:
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380:, and visual hallucinations and delusions, his may be the earliest known case where DLB was found to have been the likely cause of death.
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339:(the umbrella term that encompasses the clinical diagnoses of dementia with Lewy bodies and Parkinson's disease dementia) differs from
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997:
528:, a documentary exploring Robin Williams's Lewy body disease and how it contributed to his death, was released in September 2020.
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226:. Parkinson's disease dementia is the diagnosis when Parkinson's disease is already well established before the dementia occurs.
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diseases, even though LBD is the second most common dementia, after Alzheimer's. It is not only frustrating for families and
258:
Life expectancy of people with one of the LBD is reduced; following diagnosis it ranges on average from five to eight years.
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402:
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Velayudhan L, Ffytche D, Ballard C, Aarsland D (September 2017). "New Therapeutic Strategies for Lewy Body Dementias".
3513:
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1830:
1530:
1404:
1267:"Current concepts and controversies in the pathogenesis of Parkinson's disease dementia and Dementia with Lewy Bodies"
694:"Structural and Functional Neuroimaging of Visual Hallucinations in Lewy Body Disease: A Systematic Literature Review"
537:
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3439:
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3331:
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511:, Canadian ice hockey player, was diagnosed with possible LBD, but a post-mortem brain autopsy found that he had
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331:. Upon autopsy, his widow said he was found to have diffuse Lewy body disease, while the autopsy used the term
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1721:"Robin Williams had dementia with Lewy bodies – so, what is it and why has it been eclipsed by Alzheimer's?"
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2006:
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The exact cause is unknown, but involves widespread deposits of abnormal clumps of protein that form in
799:"Neuropathology of Lewy body disease: Clinicopathological crosstalk between typical and atypical cases"
294:
1088:"Diagnosis and management of dementia with Lewy bodies: Fourth consensus report of the DLB Consortium"
3278:
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2409:
141:
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355:, "the Lewy bodies are spread widely throughout the brain, as was the case with Robin Williams."
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as the causative subtype of PDD. DLB is marked by the presence of Lewy bodies primarily in the
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Robin Williams (shown in 2011): his widow said he was diagnosed on autopsy with Lewy bodies.
2034:"Pianist and composer Andre Gagnon, dead at 84, remembered as musical 'jack of all trades'"
3185:
2876:
2405:"Robin Williams' final days detailed in touching trailer for new documentary Robin's Wish"
1981:"Ron Cobb, designer of the 'Alien' Ship and the 'Back to the Future' DeLorean, dies at 83"
1802:
861:"Advocacy, education, and the role of not-for-profit organizations in Lewy body dementias"
541:
455:
244:
LBD usually develops after the age of 50. Men are more likely to be diagnosed than women.
196:
183:
117:
95:
992:(5th ed.). Arlington, VA: American Psychiatric Association. 2013. pp. 603–604.
524:
422:
182:. Lewy bodies and neurites have been found to develop from the aggregation of misfolded
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is a book, one-man comedy, and film about a young man with relationship problems and
463:
443:
429:
394:
384:
286:
200:
99:
90:) gives Lewy body disease as the causative subtype of dementia with Lewy bodies, and
65:
1434:
1019:(5th ed.). Arlington, VA: American Psychiatric Association. 2013. p. 619.
972:
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17:
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418:
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363:
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133:
69:
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1583:
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1103:
660:
98:, and Parkinson's disease dementia with Lewy bodies primarily in the subcortical
53:. As of 2014, they were more often misdiagnosed than any other common dementia.
2723:
2684:
2626:
508:
488:
406:
1498:
1465:
1253:
1229:
1140:"Non-pharmacological interventions for Lewy body dementia: a systematic review"
645:"Lewy Body Dementias: Dementia With Lewy Bodies and Parkinson Disease Dementia"
2834:
2704:
2549:
2545:
2458:"Robin Williams' Final Days Revealed in Touching New Documentary Robin's Wish"
1773:
1756:
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956:
877:
760:
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459:
2321:
2944:
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2883:
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2798:
2272:"Tom Seaver, Mets' star who won 3 Cy Young awards and 311 games, dead at 75"
2119:"Philip Rock, ex-Senate leader known for mentoring and bipartisanship, dies"
1935:
710:
405:, who created the plastic pink flamingo, American radio and television host
281:
175:
155:
61:
1782:
1757:"Dementia with Lewy bodies and the neurobehavioral decline of Mervyn Peake"
1705:
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1302:
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1173:
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1061:
964:
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Individuals from industry or government who have or died from LBD include
3124:
3116:
3082:
2936:
2839:
2192:"Arnold R. Hirsch dies; analyzed Chicago segregation in influential book"
414:
328:
34:
2509:
1321:"Epidemiology, pathology, and pathogenesis of dementia with Lewy bodies"
2482:"Sleepwalk with Me: Comedian's sleep disorder experience comes to film"
2011:
1371:
815:
798:
324:
2433:"Robin Williams' Struggles on Final Film Set Detailed by His Director"
207:
and the two conditions may represent different points on a continuum.
154:
A genetic architecture that predisposes an individual to some disease
3163:
2904:
2871:
2540:
2521:
57:
491:, American professional basketball player and coach, died from LBD.
387:, the actress known for her role as Sophia on the television series
3419:
Spinal muscular atrophy with lower extremity predominance (SMALED)
1883:"Don Featherstone dies at 79; creator of the plastic pink flamingo"
1831:"Nicholas King dies at 79; actor helped preserve the Watts Towers"
1017:
Diagnostic and statistical manual of mental disorders : DSM-5
990:
Diagnostic and statistical manual of mental disorders : DSM-5
335:. The vocabulary associated with Lewy pathology causes confusion.
311:
87:
1531:"Robin Williams' widow speaks: Depression didn't kill my husband"
1252:
Material was copied from this source, which is available under a
383:
Other entertainers and artists who have or died from LBD include
33:(LBD) is an umbrella term for two similar and common subtypes of
2378:"Study shows hockey Hall of Famer Stan Mikita suffered from CTE"
147:
2577:
136:
motor symptoms, neuropsychiatric symptoms, impaired cognition,
1958:"Pierre Lalonde souffrait aussi de la démence à corps de Lewy"
1212:
MenšĂková K, MatÄ›j R, Colosimo C, et al. (January 2022).
1342:
Taylor JP, McKeith IG, Burn DJ, et al. (February 2020).
1138:
Connors MH, Quinto L, McKeith IG, et al. (August 2018).
943:
Lin YW, Truong D (April 2019). "Diffuse Lewy body disease".
1638:"LBDA Clarifies Autopsy Report on Comedian, Robin Williams"
1086:
McKeith IG, Boeve BF, Dickson DW, et al. (July 2017).
1409:
Dementia with Lewy bodies: clinical and biological aspects
1265:
Weil RS, Lashley TL, Bras J, Schrag AE, Schott JM (2017).
585:
Walker Z, Possin KL, Boeve BF, Aarsland D (October 2015).
2295:"Andy Carey, Third Baseman for 1950s Yankees, Dies at 80"
1450:"Pharmacological management of dementia with Lewy dodies"
692:
Pezzoli S, Cagnin A, Bandmann O, Venneri A (July 2017).
199:, and PDD with Lewy bodies primarily in the subcortical
2348:"For Stan Mikita, all the Blackhawks memories are gone"
1081:
1079:
922:
National Institute of Neurological Disorders and Stroke
370:
as a probable case of DLB in a 2003 paper published in
2484:. American Academy of Sleep Medicine. January 26, 2012
2251:(Press release). NBA Media Ventures, LLC. May 22, 2020
1344:"New evidence on the management of Lewy body dementia"
1254:
Creative Commons Attribution 4.0 International License
2007:"Frank Bonner, 'WKRP in Cincinnati' Star, Dies at 79"
83:
Diagnostic and Statistical Manual of Mental Disorders
2499:
2177:"Indian-origin UK billionaire SP Hinduja dead at 87"
1857:"Actress and philanthropist Dina Merrill dies at 93"
924:. US National Institutes of Health. January 10, 2020
3340:
3317:
3308:
3301:
3256:
3206:
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3077:
3066:
3032:
3010:
2935:
2745:
2736:
2722:
2682:
2625:
2616:
2503:
2243:"Hall of Fame coach Jerry Sloan passes away at 78"
797:Kon T, Tomiyama M, Wakabayashi K (February 2020).
1909:"Casey Kasem and a lesson about end-of-life care"
1214:"Lewy body disease or diseases with Lewy bodies?"
308:List of people diagnosed with Parkinson's disease
1665:
1663:
1497:Haider A, Spurling BC, Sánchez-Manso JC (2021).
434:Director of the Bureau of Engraving and Printing
169:Dementia with Lewy bodies § Pathophysiology
1608:"How Lewy body dementia gripped Robin Williams"
1560:
1558:
1556:
912:
910:
908:
906:
112:Dementia with Lewy bodies § Classification
2005:Reid, Tony; Nakamura, Maglio (June 17, 2021).
1314:
1312:
1133:
1131:
638:
636:
634:
632:
630:
2589:
1750:
1748:
1746:
1524:
1522:
1520:
236:Dementia with Lewy bodies § Epidemiology
8:
2322:"Batting champ, All-Star Buckner dies at 69"
1448:Hershey LA, Coleman-Jackson R (April 2019).
854:
852:
850:
848:
846:
844:
842:
580:
578:
27:Umbrella term covering two types of dementia
2217:"Jessie Isabelle Price Dies On November 12"
1979:Bartlett R, Parker R (September 21, 2020).
918:"Lewy body dementia: Hope through research"
3314:
3305:
3074:
2742:
2733:
2622:
2596:
2582:
2574:
2500:
472:, an American historian who taught at the
254:Dementia with Lewy bodies § Prognosis
217:Dementia with Lewy bodies § Diagnosis
132:) are characterized by shared features of
2085:Shaw D, Landsberg M (February 27, 2006).
1772:
1695:
1582:
1567:"The terrorist inside my husband's brain"
1473:
1380:
1370:
1292:
1282:
1237:
1163:
1111:
886:
876:
814:
792:
790:
788:
768:
719:
709:
668:
610:
397:, a US actor and horticulturist, actress
1011:
1009:
289:often used to treat the symptoms. The
2060:"Seymour Berry, 86; Headed U.S. Agency"
1672:"Advances in dementia with Lewy bodies"
1632:
1630:
1628:
574:
553:
3385:Distal hereditary motor neuronopathies
3058:Template:Demyelinating diseases of CNS
2384:. Associated Press. September 13, 2019
1810:from the original on September 2, 2013
984:
982:
462:, and Indian-born British billionaire
458:, U.S. media mogul and philanthropist
1731:from the original on November 4, 2016
1541:from the original on November 4, 2015
7:
3236:Idiopathic intracranial hypertension
2087:"L.A. icon Otis Chandler dies at 78"
2152:"Ted Turner has Lewy Body Dementia"
2150:Deerwester J (September 28, 2018).
2099:from the original on April 26, 2007
1960:(in French). Le Journal de Montréal
1932:"L'idole d'une génération s'éteint"
1644:. November 10, 2014. Archived from
413:, graphic artist/film set designer
3467:Infantile progressive bulbar palsy
2358:from the original on June 16, 2015
2127:. January 29, 2016. Archived from
421:, and Canadian musician and actor
25:
3170:Template:Cerebrovascular diseases
2973:Frontotemporal lobar degeneration
1411:(1st ed.). Springer: Japan.
3190:For more detailed coverage, see
3168:For more detailed coverage, see
3139:For more detailed coverage, see
3105:For more detailed coverage, see
3056:For more detailed coverage, see
1606:Robbins R (September 30, 2016).
513:chronic traumatic encephalopathy
60:of the diseased brain. Known as
2248:National Basketball Association
366:died in 1968 and was diagnosed
72:, these clumps affect both the
2270:Canova D (September 2, 2020).
2190:O'Donnell M (March 26, 2018).
1642:Lewy Body Dementia Association
1565:Williams SS (September 2016).
1529:Gallman S (November 4, 2015).
1284:10.12688/f1000research.11725.1
291:Lewy Body Dementia Association
1:
3483:Amyotrophic lateral sclerosis
3368:Hereditary spastic paraplegia
3226:Normal pressure hydrocephalus
1855:Dangremond S (May 23, 2017).
1829:McLellan D (April 23, 2012).
1363:10.1016/S1474-4422(19)30153-X
603:10.1016/S0140-6736(15)00462-6
3452:Progressive muscular atrophy
1956:Belanger C (June 22, 2016).
1930:Papineau P (June 23, 2016).
1907:Caffrey J (April 18, 2016).
1584:10.1212/WNL.0000000000003162
1104:10.1212/WNL.0000000000004058
859:Taylor A, Yardley C (2014).
661:10.1212/CON.0000000000000309
362:The British author and poet
126:Parkinson's disease dementia
80:. The fifth revision of the
43:Parkinson's disease dementia
2962:Primary progressive aphasia
2293:Weber B (January 7, 2012).
1796:Carlson M (July 24, 2008).
3540:
3284:Hashimoto's encephalopathy
2990:Posterior cortical atrophy
2811:Striatonigral degeneration
2662:Cavernous sinus thrombosis
1466:10.1007/s40266-018-00636-7
1230:10.1038/s41531-021-00273-9
643:Gomperts SN (April 2016).
345:diffuse Lewy body dementia
333:diffuse Lewy body dementia
305:
251:
233:
214:
166:
109:
3390:Spinal muscular atrophies
3358:Primary lateral sclerosis
3216:Intracranial hypertension
2996:Creutzfeldt–Jakob disease
2403:Huff L (August 6, 2020).
1985:www.hollywoodreporter.com
1861:Town and Country Magazine
1798:"Obituary: Estelle Getty"
1774:10.1001/archneur.60.6.889
1688:10.1177/17562864211057666
1417:10.1007/978-4-431-55948-1
1156:10.1017/S0033291717003257
1054:10.1007/s11910-017-0778-2
957:10.1016/j.jns.2019.02.021
878:10.1186/s13195-014-0059-0
761:10.1016/j.ncl.2017.01.004
480:, an American veterinary
474:University of New Orleans
353:dementia with Lewy bodies
349:diffuse Lewy body disease
122:dementia with Lewy bodies
39:dementia with Lewy bodies
3457:Progressive bulbar palsy
3248:Intracranial hypotension
3231:Choroid plexus papilloma
2645:Herpesviral encephalitis
2320:Kelly M (May 27, 2019).
1319:Latimer CS, Montine TJ.
1042:Curr Neurol Neurosci Rep
649:Continuum (Minneap Minn)
347:is more commonly called
78:autonomic nervous system
2969:Frontotemporal dementia
2655:Encephalitis lethargica
2346:Kuc C (June 15, 2015).
1881:Woo E (June 24, 2015).
1755:Sahlas DJ (June 2003).
1218:npj Parkinson's Disease
711:10.3390/brainsci7070084
64:(discovered in 1912 by
3274:Hepatic encephalopathy
1676:Ther Adv Neurol Disord
743:Galasko D (May 2017).
655:(2 Dementia): 435–63.
317:
267:Advocacy and awareness
74:central nervous system
3332:Ataxia–telangiectasia
3289:Static encephalopathy
3012:Mitochondrial disease
2850:Spasmodic torticollis
2760:Basal ganglia disease
2437:Entertainment Tonight
2221:The Southampton Press
2092:The Los Angeles Times
1835:The Los Angeles Times
1682:: 17562864211057666.
1670:Armstrong MJ (2021).
745:"Lewy Body Disorders"
587:"Lewy body dementias"
493:Major League Baseball
487:In the sports realm,
478:Jessie Isabelle Price
315:
306:Further information:
252:Further information:
234:Further information:
215:Further information:
167:Further information:
142:visual hallucinations
110:Further information:
3279:Toxic encephalopathy
2985:Lewy bodies dementia
2410:Entertainment Weekly
1499:"Lewy Body Dementia"
163:Cause and mechanisms
18:Lewy bodies dementia
3519:Cognitive disorders
3327:Friedreich's ataxia
2710:Meningoencephalitis
2650:Limbic encephalitis
2223:. November 23, 2015
2131:on February 1, 2016
2066:. December 27, 2008
1612:Scientific American
865:Alzheimers Res Ther
403:Donald Featherstone
302:Notable individuals
262:Society and culture
193:Parkinson's disease
130:Parkinson's disease
92:Parkinson's disease
51:Parkinson's disease
3514:Lewy body dementia
3363:Pseudobulbar palsy
3101:Status epilepticus
3052:Multiple sclerosis
2889:Myoclonic epilepsy
2752:movement disorders
2698:Acute disseminated
2640:Viral encephalitis
2299:The New York Times
2040:. December 3, 2020
1648:on August 12, 2020
816:10.1111/neup.12597
597:(10004): 1683–97.
519:In popular culture
454:politician of the
409:, Canadian singer
337:Lewy body dementia
318:
293:(LBDA) and the UK
188:misfolded proteins
31:Lewy body dementia
3501:
3500:
3497:
3496:
3493:
3492:
3297:
3296:
3202:
3201:
3141:Template:Headache
3107:Template:Epilepsy
3028:
3027:
3002:Vascular dementia
2845:Status dystonicus
2718:
2717:
2693:Encephalomyelitis
2571:
2570:
2196:Chicago Sun Times
2124:Chicago Sun-Times
1887:Los Angeles Times
1426:978-4-431-55948-1
1192:meshb.nlm.nih.gov
544:, including LBD.
540:, a precursor to
533:Sleepwalk with Me
484:, died from LBD.
439:Los Angeles Times
417:, American actor
341:Lewy body disease
327:, and increasing
295:Lewy Body Society
118:synucleinopathies
47:Lewy body disease
16:(Redirected from
3531:
3315:
3306:
3264:Brain herniation
3075:
2915:Intention tremor
2910:Essential tremor
2775:Postencephalitic
2743:
2734:
2623:
2604:Diseases of the
2598:
2591:
2584:
2575:
2501:
2494:
2493:
2491:
2489:
2478:
2472:
2471:
2469:
2468:
2453:
2447:
2446:
2444:
2443:
2428:
2422:
2421:
2419:
2417:
2400:
2394:
2393:
2391:
2389:
2374:
2368:
2367:
2365:
2363:
2343:
2337:
2336:
2334:
2332:
2317:
2311:
2310:
2308:
2306:
2290:
2284:
2283:
2281:
2279:
2267:
2261:
2260:
2258:
2256:
2239:
2233:
2232:
2230:
2228:
2213:
2207:
2206:
2204:
2202:
2187:
2181:
2180:
2173:
2167:
2166:
2164:
2162:
2147:
2141:
2140:
2138:
2136:
2115:
2109:
2108:
2106:
2104:
2082:
2076:
2075:
2073:
2071:
2056:
2050:
2049:
2047:
2045:
2030:
2024:
2023:
2021:
2019:
2002:
1996:
1995:
1993:
1991:
1976:
1970:
1969:
1967:
1965:
1953:
1947:
1946:
1944:
1942:
1927:
1921:
1920:
1918:
1916:
1904:
1898:
1897:
1895:
1893:
1878:
1872:
1871:
1869:
1867:
1852:
1846:
1845:
1843:
1841:
1826:
1820:
1819:
1817:
1815:
1793:
1787:
1786:
1776:
1752:
1741:
1740:
1738:
1736:
1725:The Conversation
1716:
1710:
1709:
1699:
1667:
1658:
1657:
1655:
1653:
1634:
1623:
1622:
1620:
1618:
1603:
1597:
1596:
1586:
1562:
1551:
1550:
1548:
1546:
1526:
1515:
1514:
1494:
1488:
1487:
1477:
1445:
1439:
1438:
1401:
1395:
1394:
1384:
1374:
1348:
1339:
1333:
1332:
1330:
1328:
1316:
1307:
1306:
1296:
1286:
1262:
1256:
1251:
1241:
1209:
1203:
1202:
1200:
1198:
1184:
1178:
1177:
1167:
1135:
1126:
1125:
1115:
1083:
1074:
1073:
1037:
1031:
1030:
1013:
1004:
1003:
986:
977:
976:
940:
934:
933:
931:
929:
914:
901:
900:
890:
880:
856:
837:
836:
818:
794:
783:
782:
772:
740:
734:
733:
723:
713:
689:
683:
682:
672:
640:
625:
624:
614:
582:
562:
558:
470:Arnold R. Hirsch
390:The Golden Girls
197:cortical regions
96:cortical regions
21:
3539:
3538:
3534:
3533:
3532:
3530:
3529:
3528:
3504:
3503:
3502:
3489:
3415:Congenital DSMA
3336:
3293:
3252:
3198:
3186:Sleep disorders
3174:
3151:Cerebrovascular
3145:
3111:
3068:
3062:
3024:
3006:
2931:
2877:Choreoathetosis
2750:
2727:
2714:
2678:
2612:
2602:
2572:
2567:
2566:
2512:
2498:
2497:
2487:
2485:
2480:
2479:
2475:
2466:
2464:
2455:
2454:
2450:
2441:
2439:
2430:
2429:
2425:
2415:
2413:
2402:
2401:
2397:
2387:
2385:
2376:
2375:
2371:
2361:
2359:
2352:Chicago Tribune
2345:
2344:
2340:
2330:
2328:
2319:
2318:
2314:
2304:
2302:
2292:
2291:
2287:
2277:
2275:
2269:
2268:
2264:
2254:
2252:
2241:
2240:
2236:
2226:
2224:
2215:
2214:
2210:
2200:
2198:
2189:
2188:
2184:
2175:
2174:
2170:
2160:
2158:
2149:
2148:
2144:
2134:
2132:
2117:
2116:
2112:
2102:
2100:
2084:
2083:
2079:
2069:
2067:
2064:Washington Post
2058:
2057:
2053:
2043:
2041:
2032:
2031:
2027:
2017:
2015:
2004:
2003:
1999:
1989:
1987:
1978:
1977:
1973:
1963:
1961:
1955:
1954:
1950:
1940:
1938:
1929:
1928:
1924:
1914:
1912:
1906:
1905:
1901:
1891:
1889:
1880:
1879:
1875:
1865:
1863:
1854:
1853:
1849:
1839:
1837:
1828:
1827:
1823:
1813:
1811:
1803:theguardian.com
1795:
1794:
1790:
1754:
1753:
1744:
1734:
1732:
1718:
1717:
1713:
1669:
1668:
1661:
1651:
1649:
1636:
1635:
1626:
1616:
1614:
1605:
1604:
1600:
1577:(13): 1308–11.
1564:
1563:
1554:
1544:
1542:
1528:
1527:
1518:
1496:
1495:
1491:
1447:
1446:
1442:
1427:
1403:
1402:
1398:
1346:
1341:
1340:
1336:
1326:
1324:
1323:. UpToDate, Inc
1318:
1317:
1310:
1264:
1263:
1259:
1211:
1210:
1206:
1196:
1194:
1186:
1185:
1181:
1150:(11): 1749–58.
1137:
1136:
1129:
1085:
1084:
1077:
1039:
1038:
1034:
1027:
1015:
1014:
1007:
1000:
988:
987:
980:
945:J. Neurol. Sci.
942:
941:
937:
927:
925:
916:
915:
904:
858:
857:
840:
796:
795:
786:
742:
741:
737:
691:
690:
686:
642:
641:
628:
584:
583:
576:
571:
566:
565:
559:
555:
550:
542:synucleinopathy
521:
456:Illinois Senate
310:
304:
269:
264:
256:
250:
238:
232:
219:
213:
184:alpha-synuclein
171:
165:
138:sleep disorders
114:
108:
28:
23:
22:
15:
12:
11:
5:
3537:
3535:
3527:
3526:
3521:
3516:
3506:
3505:
3499:
3498:
3495:
3494:
3491:
3490:
3488:
3487:
3486:
3485:
3474:
3473:
3472:
3471:
3470:
3469:
3464:
3454:
3449:
3448:
3447:
3442:
3437:
3436:
3435:
3430:
3425:
3417:
3412:
3407:
3402:
3397:
3387:
3373:
3372:
3371:
3370:
3365:
3360:
3346:
3344:
3338:
3337:
3335:
3334:
3329:
3323:
3321:
3312:
3303:
3299:
3298:
3295:
3294:
3292:
3291:
3286:
3281:
3276:
3271:
3266:
3260:
3258:
3254:
3253:
3251:
3250:
3245:
3243:Cerebral edema
3240:
3239:
3238:
3233:
3228:
3223:
3212:
3210:
3204:
3203:
3200:
3199:
3197:
3196:
3195:
3194:
3192:Template:Sleep
3182:
3180:
3176:
3175:
3173:
3172:
3166:
3161:
3155:
3153:
3147:
3146:
3144:
3143:
3137:
3132:
3127:
3121:
3119:
3113:
3112:
3110:
3109:
3103:
3098:
3093:
3087:
3085:
3072:
3064:
3063:
3061:
3060:
3054:
3049:
3044:
3038:
3036:
3030:
3029:
3026:
3025:
3023:
3022:
3020:Leigh syndrome
3016:
3014:
3008:
3007:
3005:
3004:
2993:
2992:
2987:
2982:
2981:
2980:
2966:
2965:
2964:
2959:
2958:
2957:
2941:
2939:
2933:
2932:
2930:
2929:
2924:
2919:
2918:
2917:
2912:
2901:
2900:
2899:
2898:
2893:
2892:
2891:
2881:
2880:
2879:
2869:
2864:
2863:
2862:
2857:
2852:
2847:
2831:
2830:
2829:
2828:
2823:
2818:
2813:
2808:
2807:
2806:
2796:
2795:
2794:
2784:
2783:
2782:
2777:
2772:
2756:
2754:
2747:Extrapyramidal
2740:
2731:
2729:encephalopathy
2720:
2719:
2716:
2715:
2713:
2712:
2707:
2702:
2701:
2700:
2689:
2687:
2680:
2679:
2677:
2676:
2675:
2674:
2664:
2659:
2658:
2657:
2652:
2647:
2642:
2631:
2629:
2620:
2614:
2613:
2606:nervous system
2603:
2601:
2600:
2593:
2586:
2578:
2569:
2568:
2565:
2564:
2553:
2533:
2513:
2508:
2507:
2505:
2504:Classification
2496:
2495:
2473:
2448:
2423:
2395:
2369:
2338:
2312:
2285:
2262:
2234:
2208:
2182:
2179:. 17 May 2023.
2168:
2142:
2110:
2077:
2051:
2025:
1997:
1971:
1948:
1922:
1899:
1873:
1847:
1821:
1788:
1742:
1711:
1659:
1624:
1598:
1552:
1516:
1489:
1440:
1425:
1407:, ed. (2017).
1396:
1334:
1308:
1257:
1204:
1188:"MeSH Browser"
1179:
1127:
1075:
1032:
1025:
1005:
998:
978:
935:
902:
838:
803:Neuropathology
784:
735:
684:
626:
573:
572:
570:
567:
564:
563:
552:
551:
549:
546:
520:
517:
482:microbiologist
448:Philip J. Rock
411:Pierre Lalonde
378:attention span
373:JAMA Neurology
357:Ian G. McKeith
321:Robin Williams
303:
300:
287:antipsychotics
268:
265:
263:
260:
249:
246:
231:
228:
212:
209:
164:
161:
107:
106:Classification
104:
49:that includes
26:
24:
14:
13:
10:
9:
6:
4:
3:
2:
3536:
3525:
3522:
3520:
3517:
3515:
3512:
3511:
3509:
3484:
3481:
3480:
3479:
3476:
3475:
3468:
3465:
3463:
3460:
3459:
3458:
3455:
3453:
3450:
3446:
3443:
3441:
3438:
3434:
3431:
3429:
3426:
3424:
3421:
3420:
3418:
3416:
3413:
3411:
3408:
3406:
3403:
3401:
3398:
3396:
3393:
3392:
3391:
3388:
3386:
3383:
3382:
3381:
3379:
3375:
3374:
3369:
3366:
3364:
3361:
3359:
3356:
3355:
3354:
3352:
3348:
3347:
3345:
3343:
3339:
3333:
3330:
3328:
3325:
3324:
3322:
3320:
3316:
3313:
3311:
3307:
3304:
3300:
3290:
3287:
3285:
3282:
3280:
3277:
3275:
3272:
3270:
3269:Reye syndrome
3267:
3265:
3262:
3261:
3259:
3255:
3249:
3246:
3244:
3241:
3237:
3234:
3232:
3229:
3227:
3224:
3222:
3221:Hydrocephalus
3219:
3218:
3217:
3214:
3213:
3211:
3209:
3205:
3193:
3189:
3188:
3187:
3184:
3183:
3181:
3177:
3171:
3167:
3165:
3162:
3160:
3157:
3156:
3154:
3152:
3148:
3142:
3138:
3136:
3133:
3131:
3128:
3126:
3123:
3122:
3120:
3118:
3114:
3108:
3104:
3102:
3099:
3097:
3094:
3092:
3089:
3088:
3086:
3084:
3080:
3076:
3073:
3071:
3065:
3059:
3055:
3053:
3050:
3048:
3045:
3043:
3040:
3039:
3037:
3035:
3034:Demyelinating
3031:
3021:
3018:
3017:
3015:
3013:
3009:
3003:
3000:
2999:
2998:
2997:
2991:
2988:
2986:
2983:
2979:
2976:
2975:
2974:
2970:
2967:
2963:
2960:
2956:
2953:
2952:
2951:
2948:
2947:
2946:
2943:
2942:
2940:
2938:
2934:
2928:
2925:
2923:
2922:Restless legs
2920:
2916:
2913:
2911:
2908:
2907:
2906:
2903:
2902:
2897:
2894:
2890:
2887:
2886:
2885:
2882:
2878:
2875:
2874:
2873:
2870:
2868:
2865:
2861:
2860:Blepharospasm
2858:
2856:
2853:
2851:
2848:
2846:
2843:
2842:
2841:
2838:
2837:
2836:
2833:
2832:
2827:
2824:
2822:
2819:
2817:
2816:Hemiballismus
2814:
2812:
2809:
2805:
2802:
2801:
2800:
2797:
2793:
2790:
2789:
2788:
2785:
2781:
2778:
2776:
2773:
2771:
2768:
2767:
2766:
2763:
2762:
2761:
2758:
2757:
2755:
2753:
2748:
2744:
2741:
2739:
2735:
2732:
2730:
2725:
2721:
2711:
2708:
2706:
2703:
2699:
2696:
2695:
2694:
2691:
2690:
2688:
2686:
2681:
2673:
2670:
2669:
2668:
2667:Brain abscess
2665:
2663:
2660:
2656:
2653:
2651:
2648:
2646:
2643:
2641:
2638:
2637:
2636:
2633:
2632:
2630:
2628:
2624:
2621:
2619:
2615:
2611:
2607:
2599:
2594:
2592:
2587:
2585:
2580:
2579:
2576:
2563:
2559:
2558:
2554:
2551:
2547:
2543:
2542:
2538:
2534:
2532:
2528:
2524:
2523:
2519:
2515:
2514:
2511:
2506:
2502:
2483:
2477:
2474:
2463:
2459:
2452:
2449:
2438:
2434:
2427:
2424:
2412:
2411:
2406:
2399:
2396:
2383:
2379:
2373:
2370:
2357:
2353:
2349:
2342:
2339:
2327:
2323:
2316:
2313:
2301:. p. A26
2300:
2296:
2289:
2286:
2273:
2266:
2263:
2250:
2249:
2244:
2238:
2235:
2222:
2218:
2212:
2209:
2197:
2193:
2186:
2183:
2178:
2172:
2169:
2161:September 30,
2157:
2153:
2146:
2143:
2130:
2126:
2125:
2120:
2114:
2111:
2098:
2094:
2093:
2088:
2081:
2078:
2065:
2061:
2055:
2052:
2039:
2035:
2029:
2026:
2014:
2013:
2008:
2001:
1998:
1990:September 26,
1986:
1982:
1975:
1972:
1959:
1952:
1949:
1937:
1934:(in French).
1933:
1926:
1923:
1910:
1903:
1900:
1888:
1884:
1877:
1874:
1862:
1858:
1851:
1848:
1836:
1832:
1825:
1822:
1809:
1805:
1804:
1799:
1792:
1789:
1784:
1780:
1775:
1770:
1767:(6): 889–92.
1766:
1762:
1758:
1751:
1749:
1747:
1743:
1730:
1726:
1722:
1715:
1712:
1707:
1703:
1698:
1693:
1689:
1685:
1681:
1677:
1673:
1666:
1664:
1660:
1647:
1643:
1639:
1633:
1631:
1629:
1625:
1613:
1609:
1602:
1599:
1594:
1590:
1585:
1580:
1576:
1572:
1568:
1561:
1559:
1557:
1553:
1540:
1536:
1532:
1525:
1523:
1521:
1517:
1512:
1508:
1504:
1500:
1493:
1490:
1485:
1481:
1476:
1471:
1467:
1463:
1460:(4): 309–19.
1459:
1455:
1451:
1444:
1441:
1436:
1432:
1428:
1422:
1418:
1414:
1410:
1406:
1400:
1397:
1392:
1388:
1383:
1378:
1373:
1368:
1364:
1360:
1357:(2): 157–69.
1356:
1352:
1351:Lancet Neurol
1345:
1338:
1335:
1322:
1315:
1313:
1309:
1304:
1300:
1295:
1290:
1285:
1280:
1276:
1272:
1268:
1261:
1258:
1255:
1249:
1245:
1240:
1235:
1231:
1227:
1223:
1219:
1215:
1208:
1205:
1193:
1189:
1183:
1180:
1175:
1171:
1166:
1161:
1157:
1153:
1149:
1145:
1141:
1134:
1132:
1128:
1123:
1119:
1114:
1109:
1105:
1101:
1098:(1): 88–100.
1097:
1093:
1089:
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464:S. P. Hinduja
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3310:Degenerative
3047:Inflammatory
2994:
2927:Stiff-person
2765:Parkinsonism
2738:Degenerative
2635:Encephalitis
2618:Inflammation
2608:, primarily
2555:
2535:
2516:
2486:. Retrieved
2476:
2465:. Retrieved
2461:
2456:VanHoose B.
2451:
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1760:
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1719:McKeith IG.
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423:André Gagnon
419:Frank Bonner
399:Dina Merrill
388:
382:
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368:posthumously
364:Mervyn Peake
361:
348:
344:
340:
336:
332:
319:
270:
257:
243:
239:
230:Epidemiology
224:parkinsonism
220:
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134:parkinsonism
115:
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3462:Fazio–Londe
3302:Both/either
3096:Generalised
2955:Early-onset
2950:Alzheimer's
2685:spinal cord
2044:November 9,
1814:October 13,
1454:Drugs Aging
1372:10871/36535
1197:17 November
1144:Psychol Med
749:Neurol Clin
509:Stan Mikita
489:Jerry Sloan
407:Casey Kasem
278:Alzheimer's
274:Parkinson's
176:Lewy bodies
62:Lewy bodies
3508:Categories
3070:paroxysmal
3042:Autoimmune
2835:Dyskinesia
2705:Meningitis
2683:Brain and
2467:2020-08-20
2442:2020-08-20
2274:. Fox News
1678:(Review).
1503:StatPearls
1456:(Review).
1353:(Review).
1273:(Review).
1220:(Review).
1146:(Review).
1094:(Review).
1044:(Review).
951:: 144–50.
947:(Review).
867:(Review).
704:(12): 84.
593:(Review).
569:References
501:Andy Carey
497:Tom Seaver
460:Ted Turner
452:Democratic
442:publisher
282:caregivers
156:phenotypes
151:dementia.
41:(DLB) and
3067:Episodic/
2945:Tauopathy
2896:Akathisia
2884:Myoclonus
2867:Athetosis
2799:Tauopathy
2488:April 22,
2431:Boone J.
2416:August 7,
2382:USA Today
2362:March 22,
2305:April 19,
2227:April 19,
2201:April 19,
2156:USA Today
2135:April 19,
2070:April 19,
1964:March 22,
1936:Le Devoir
1915:March 22,
1892:March 22,
1866:March 22,
1840:April 19,
1652:April 19,
1571:Neurology
1327:August 2,
1092:Neurology
1048:(9): 68.
928:March 18,
871:(5): 59.
833:201983865
698:Brain Sci
298:disease.
248:Prognosis
211:Diagnosis
3524:Dementia
3433:SMALED2B
3428:SMALED2A
3125:Migraine
3117:Headache
3083:epilepsy
3079:Seizures
2937:Dementia
2840:Dystonia
2356:Archived
2103:July 23,
2097:Archived
2038:CTV News
2018:June 17,
1941:April 9,
1808:Archived
1783:12810496
1735:April 6,
1729:Archived
1706:34840608
1617:April 9,
1593:27672165
1545:April 6,
1539:Archived
1511:29494048
1484:30680679
1435:45950966
1405:Kosaka K
1391:31519472
1303:28928962
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1271:F1000Res
1248:35013341
1224:(1): 3.
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1122:28592453
1062:28741230
973:72335064
965:30807982
897:26082807
825:31498507
779:28410662
730:28714891
679:27042903
621:26595642
495:players
415:Ron Cobb
329:paranoia
76:and the
35:dementia
3445:SMA-PME
3440:SMA-PCH
3423:SMALED1
3135:Tension
3130:Cluster
2855:Meige's
2672:Amoebic
2562:D020961
2388:June 8,
2331:May 27,
2326:MLB.com
2255:June 8,
2012:TheWrap
1697:8613883
1475:6435621
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1239:8748648
1165:6088773
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1070:3739100
888:4468791
770:5912679
721:5532597
670:5390937
612:5792067
450:, a US
325:anxiety
58:neurons
3164:Stroke
2978:Pick's
2905:Tremor
2872:Chorea
2531:6D85.0
2462:People
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3380:only:
3353:only:
3257:Other
3179:Other
3091:Focal
2724:Brain
2627:Brain
2550:F02.8
2546:G31.8
1911:. CNN
1431:S2CID
1347:(PDF)
1066:S2CID
969:S2CID
829:S2CID
548:Notes
432:, US
88:DSM-5
3081:and
2792:PKAN
2787:NBIA
2557:MeSH
2527:6D82
2490:2018
2418:2020
2390:2020
2364:2018
2333:2019
2307:2018
2280:2020
2257:2020
2229:2018
2203:2018
2163:2018
2137:2018
2105:2008
2072:2018
2046:2021
2020:2021
1992:2020
1966:2018
1943:2018
1917:2018
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1868:2018
1842:2018
1816:2013
1779:PMID
1737:2018
1702:PMID
1654:2018
1619:2018
1589:PMID
1547:2018
1507:PMID
1480:PMID
1421:ISBN
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1299:PMID
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1199:2020
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1118:PMID
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930:2020
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775:PMID
726:PMID
675:PMID
617:PMID
276:and
178:and
148:MeSH
116:The
3395:SMA
3378:LMN
3351:UMN
3342:MND
3208:CSF
3159:TIA
2804:PSP
2780:NMS
2749:and
2610:CNS
2537:ICD
2518:ICD
1769:doi
1692:PMC
1684:doi
1579:doi
1535:CNN
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1377:PMC
1367:hdl
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