67:
43:
246:
Studies reflecting international frequency demonstrated that 2-3% of all infants in NICUs develop pulmonary interstitial emphysema. When limiting the population studied to premature infants, this frequency increases to 20-30%, with the highest frequencies occurring in infants weighing fewer than
597:
582:
99:. (This supportive tissue is called the pulmonary interstitium.) This collection of air develops as a result of alveolar and terminal bronchiolar rupture. Pulmonary interstitial emphysema is more frequent in premature infants who require
213:
Pulmonary interstitial emphysema often resolves gradually and may take 2–3 weeks. For longer durations of PIE the length of time of mechanical ventilation needed may increase and the incidence of
277:"Resolution of pulmonary interstitial emphysema following selective left main stem intubation in a premature newborn: an old procedure revisited"
24:
234:
The prevalence of pulmonary interstitial emphysema widely varies with the population studied. In a 1987 study 3% of infants admitted to the
124:
183:
Different treatments have been used to manage pulmonary interstitial emphysema with variable success. Admission/transfer to a
628:
235:
184:
130:
104:
103:
for severe lung disease. Infants with pulmonary interstitial emphysema are typically recommended for admission to a
256:
214:
194:
163:
Pulmonary interstitial emphysema is created when air bursts or ruptures through tissue from the alveoli and
152:
100:
42:
633:
175:
A chest X ray may show a "salt and pepper" appearance due to the linear lucencies that are present.
66:
601:
546:
499:
403:
354:
304:
88:
538:
491:
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96:
92:
55:
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becomes higher. Some infants may develop chronic lobar emphysema, which may require surgical
530:
483:
442:
434:
385:
338:
288:
519:"Predicting mortality in low-birth-weight infants with pulmonary interstitial emphysema"
487:
447:
422:
136:
606:
372:
Morisot C, Kacet N, Bouchez MC, Rouland V, Dubos JP, Gremillet C, et al. (1990).
622:
292:
119:
550:
503:
407:
358:
308:
327:"Early pulmonary interstitial emphysema in the newborn: a grave prognostic sign"
164:
20:
342:
591:
60:
218:
199:
147:
300:
276:
542:
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16:
Collection of air outside of the normal air space of the pulmonary alveoli
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187:(NICU) is common and expected for patients with PIE. Treatments include:
574:
472:"Pulmonary interstitial emphysema in infants less than 1000 g at birth"
390:
373:
115:
Pulmonary interstitial emphysema is a concern in any of the following:
586:
374:"Risk factors for fatal pulmonary interstitial emphysema in neonates"
142:
423:"Pulmonary interstitial emphysema in very low birthweight infants"
50:
Chest radiography showing severe pulmonary interstitial emphysema
84:
95:
of the peribronchovascular sheaths, interlobular septa, and
517:
Gaylord MS, Thieme RE, Woodall DL, Quissell BJ (1985).
191:
Lateral decubitus position with the affected side down
564:
568:
238:(NICU) developed pulmonary interstitial emphysema.
54:
35:
204:Selective Main Bronchial Intubation and Occlusion
470:Yu VY, Wong PY, Bajuk B, Szymonowicz W (1986).
421:Hart SM, McNair M, Gamsu HR, Price JF (1983).
320:
318:
8:
325:Heneghan MA, Sosulski R, Alarcon MB (1987).
275:Chalak LF, Kaiser JR, Arrington RW (2007).
565:
167:into the perivascular tissue of the lung.
65:
41:
32:
446:
389:
267:
87:outside of the normal air space of the
25:chronic obstructive pulmonary disease
7:
125:Infant respiratory distress syndrome
488:10.1111/j.1440-1754.1986.tb00221.x
14:
293:10.1111/j.1460-9592.2006.02044.x
77:Pulmonary interstitial emphysema
36:Pulmonary interstitial emphysema
1:
236:neonatal intensive care unit
185:neonatal intensive care unit
131:Meconium aspiration syndrome
105:neonatal intensive care unit
91:, found instead inside the
650:
343:10.1177/000992288702600707
257:Bronchopulmonary dysplasia
215:bronchopulmonary dysplasia
195:High-frequency ventilation
18:
49:
40:
19:Not to be confused with
153:Mechanical ventilation
101:mechanical ventilation
535:10.1542/peds.76.2.219
83:) is a collection of
23:, which is a type of
439:10.1136/adc.58.8.612
331:Clin Pediatr (Phila)
629:Respiratory therapy
21:pulmonary emphysema
391:10.1007/bf01959402
616:
615:
93:connective tissue
89:pulmonary alveoli
74:
73:
30:Medical condition
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281:Paediatr Anaesth
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70:
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45:
33:
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619:
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476:Aust Paediatr J
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159:Pathophysiology
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97:visceral pleura
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17:
12:
11:
5:
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569:Classification
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561:External links
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427:Arch Dis Child
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137:Amniotic fluid
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72:
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58:
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38:
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29:
15:
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2:
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529:(2): 219–24.
528:
524:
520:
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510:
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497:
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489:
485:
482:(3): 189–92.
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378:Eur J Pediatr
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242:International
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596:
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433:(8): 612–5.
430:
426:
416:
384:(7): 493–5.
381:
377:
367:
337:(7): 361–5.
334:
330:
287:(2): 183–6.
284:
280:
270:
245:
233:
225:Epidemiology
212:
182:
174:
162:
114:
80:
76:
75:
634:Pulmonology
219:lobectomies
165:bronchioles
120:Prematurity
623:Categories
523:Pediatrics
263:References
148:Infections
139:aspiration
61:Pediatrics
209:Prognosis
200:Lobectomy
179:Treatment
171:Diagnosis
56:Specialty
551:38763776
504:22291777
408:23256278
359:26285767
309:21128728
301:17238893
251:See also
247:1000 g.
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496:3767787
457:6351760
448:1628320
400:2347343
351:3595042
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143:Sepsis
127:(IRDS)
63:
607:518.1
592:P25.0
547:S2CID
500:S2CID
404:S2CID
355:S2CID
305:S2CID
133:(MAS)
111:Cause
602:9-CM
539:PMID
492:PMID
453:PMID
396:PMID
347:PMID
297:PMID
598:ICD
583:ICD
531:doi
484:doi
443:PMC
435:doi
386:doi
382:149
339:doi
289:doi
85:air
81:PIE
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317:^
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575:D
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79:(
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