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Limme, B.; Dresse, M.-F.; Ketelslegers, O.; Rigo, V.; Hoyoux, C. (2008). "La pyknocytose infantile : Une anémie néonatale mal connue à propos de 5 cas" [Infantile pyknocytosis: A rare form of neonatal hemolytic anemia. 5 case-studies].
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or the presence of an oxidative factor. The diagnosis of infantile pyknocytosis is essentially based on the peripheral blood smear, with additional diagnostic investigations to rule out similarly presenting conditions such as
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for this condition has not been established but some evidence, including the presence of dehydrated red cells on peripheral blood smear that seem to have undergone oxidative stress, points to causes that include deficiency of
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levels are greater than normal for the age of the infant, and blood transfusion if hemoglobin is found to be unacceptably low or decreasing based on clinical judgement of laboratory values.
46:. The associated hemolytic anemia is often transient with peak incidence at 3–4 weeks, with spontaneous and complete resolution by four to six months of life. An
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Infantile pyknocytosis is the most commonly associated condition, and is a rare pediatric hematological condition. It is a potential cause of neonatal
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that appear distorted, irregular and small with abnormal projections and would typically be identified by a medical scientist and verified by a
68:. Both of these conditions can also result in pyknocytes observable on the blood smear. Treatment involves phototherapy if blood
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Eyssette-Guerreau, Stephanie; Bader-Meunier, Brigitte; Garcon, Loic; Guitton, C.; Cynober, Therese (2006).
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is a hematologic state characterized by the presence of pyknocytes in the blood. Pyknocytes are
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