253:
230:
1054:
127:
152:
504:
4996:
259:
158:
2494:
Aramaki O, Shirasugi N, Takayama T, Shimazu M, Kitajima M, Ikeda Y, et al. (January 2004). "Programmed death-1-programmed death-L1 interaction is essential for induction of regulatory cells by intratracheal delivery of alloantigen".
3832:
2971:
2766:
Mataki N, Kikuchi K, Kawai T, Higashiyama M, Okada Y, Kurihara C, et al. (February 2007). "Expression of PD-1, PD-L1, and PD-L2 in the liver in autoimmune liver diseases".
266:
165:
1176:
5037:
2803:
Wang SC, Lin CH, Ou TT, Wu CC, Tsai WC, Hu CJ, et al. (April 2007). "Ligands for programmed cell death 1 gene in patients with systemic lupus erythematosus".
3822:
1425:
Latchman Y, Wood CR, Chernova T, Chaudhary D, Borde M, Chernova I, et al. (March 2001). "PD-L2 is a second ligand for PD-1 and inhibits T cell activation".
2422:
Youngnak P, Kozono Y, Kozono H, Iwai H, Otsuki N, Jin H, et al. (August 2003). "Differential binding properties of B7-H1 and B7-DC to programmed death-1".
1746:
Sharpe AH, Wherry EJ, Ahmed R, Freeman GJ (March 2007). "The function of programmed cell death 1 and its ligands in regulating autoimmunity and infection".
3802:
752:
733:
88:
4664:
2988:
2964:
1237:
4395:
1060:
structure of high affinity mutant hPDL2-hPD1 complex (1.986 Å) reported in Tang and Kim, PNAS 2019. hPD-1: green/blue, hPD-L2: red/orange/yellow
4383:
4161:
4447:
4442:
4388:
4168:
2949:
1402:
1384:
5061:
5056:
3901:
3827:
2957:
2065:
1236:. Both PD-L1 and PD-L2 can inhibit T cell proliferation and inflammatory cytokine production. Blocking PD-L2 has been shown to exacerbate
252:
5030:
4930:
4925:
4920:
4915:
3842:
2871:
959:
229:
4895:
952:
1468:
4131:
2453:"Preferential contribution of B7-H1 to programmed death-1-mediated regulation of hapten-specific allergic inflammatory responses"
2142:"PD-L2 expression is correlated with the molecular and clinical features of glioma, and acts as an unfavorable prognostic factor"
2293:"PD-L1, PD-L2 and PD-1 expression in metastatic melanoma: Correlation with tumor-infiltrating immune cells and clinical outcome"
5066:
4699:
4193:
3879:
1371:
1350:
1269:
1225:
1042:
5023:
4338:
3874:
2612:"Clinical significance of programmed death-1 ligand-1 and programmed death-1 ligand-2 expression in human esophageal cancer"
2242:"Progression of Disease Within 24 Months in Follicular Lymphoma Is Associated With Reduced Intratumoral Immune Infiltration"
1367:
1303:
regulation is not as well studied as the role of PD-L1. In mouse cell cultures, PD-L2 expression on tumor cells suppressed
151:
126:
4835:
4307:
4302:
4247:
3981:
3430:
1149:
1053:
1346:
4529:
4252:
265:
164:
68:
3847:
2690:"No evidence for dualism in function and receptors: PD-L2/B7-DC is an inhibitory regulator of human T cell activation"
258:
157:
4559:
2984:
2888:
1077:
1073:
1030:
2731:
Abelson AK, Johansson CM, Kozyrev SV, Kristjansdottir H, Gunnarsson I, Svenungsson E, et al. (January 2007).
3425:
4609:
3504:
2843:
797:
76:
2389:"Blockade of programmed death-1 ligands on dendritic cells enhances T cell activation and cytokine production"
1682:"A high-affinity human PD-1/PD-L2 complex informs avenues for small-molecule immune checkpoint drug discovery"
1099:
PD-L2 bound to murine PD-1 has been determined. as well as the structure of the hPD-L2/mutant hPD-1 complex.
4573:
2864:
2849:
1113:
778:
3916:
3911:
3906:
3896:
3203:
3131:
1300:
1281:
1133:
1038:
1080:
in the extracellular region, a transmembrane domain, and a cytoplasmic domain. PD-L2 shares considerable
3260:
3178:
1209:
1092:
1065:
1057:
1790:
1534:
Chen L (May 2004). "Co-inhibitory molecules of the B7-CD28 family in the control of T-cell immunity".
4497:
4210:
2839:
2647:"PD-L2:PD-1 involvement in T cell proliferation, cytokine production, and integrin-mediated adhesion"
2191:"Correlation Between PD-L2 Expression and Clinical Outcome in Solid Cancer Patients: A Meta-Analysis"
2019:
1693:
1311:
1284:, efforts have been made to block PD-1 and PD-L1, resulting in FDA approved inhibitors for both (see
1157:
140:
55:
4524:
4343:
1314:
or prognostic indicator. PD-L2 expression has been shown to predict response to PD-1 blockade with
2089:
Tanegashima T, Togashi Y, Azuma K, Kawahara A, Ideguchi K, Sugiyama D, et al. (August 2019).
503:
3931:
3665:
2857:
2791:
2688:
Pfistershammer K, Klauser C, Pickl WF, Stöckl J, Leitner J, Zlabinger G, et al. (May 2006).
2676:
2520:
2482:
1839:
Lesterhuis WJ, Steer H, Lake RA (October 2011). "PD-L2 is predominantly expressed by Th2 cells".
1821:
1771:
1559:
1450:
100:
935:
914:
888:
867:
1877:
2820:
2783:
2754:
2719:
2668:
2633:
2598:
2555:
2512:
2474:
2439:
2410:
2375:
2322:
2273:
2222:
2171:
2122:
2047:
1983:
1929:
1856:
1813:
1763:
1721:
1662:
1611:
1551:
1513:
1442:
1193:
1189:
1081:
1034:
96:
48:
5007:
5003:
4995:
4704:
4437:
4358:
3921:
3114:
3040:
2812:
2775:
2744:
2709:
2701:
2658:
2623:
2588:
2580:
2545:
2504:
2464:
2431:
2400:
2365:
2357:
2312:
2304:
2263:
2253:
2212:
2202:
2161:
2153:
2112:
2102:
2037:
2027:
1973:
1965:
1919:
1848:
1805:
1755:
1711:
1701:
1652:
1642:
1601:
1593:
1543:
1503:
1495:
1434:
1319:
1304:
1229:
1197:
1129:
345:
276:
220:
175:
4764:
3300:
3295:
3218:
2938:
2091:"Immune Suppression by PD-L2 against Spontaneous and Treatment-Related Antitumor Immunity"
1273:
1221:
1217:
1137:
320:
2387:
Brown JA, Dorfman DM, Ma FR, Sullivan EL, Munoz O, Wood CR, et al. (February 2003).
1631:"Crystal structure of the complex between programmed death-1 (PD-1) and its ligand PD-L2"
2023:
1952:
Ghiotto M, Gauthier L, Serriari N, Pastor S, Truneh A, Nunès JA, Olive D (August 2010).
1697:
4549:
3971:
3482:
3285:
2714:
2689:
2593:
2569:"Signal peptide prediction based on analysis of experimentally verified cleavage sites"
2568:
2451:
Tsushima F, Iwai H, Otsuki N, Abe M, Hirose S, Yamazaki T, et al. (October 2003).
2370:
2346:"B7-DC, a new dendritic cell molecule with potent costimulatory properties for T cells"
2345:
2317:
2292:
2268:
2241:
2217:
2190:
2166:
2141:
2042:
2007:
1978:
1953:
1716:
1681:
1657:
1630:
1606:
1582:"B7-DC, a new dendritic cell molecule with potent costimulatory properties for T cells"
1581:
1508:
1483:
1249:
1245:
1241:
1180:
1153:
1117:
59:, B7DC, Btdc, CD273, PD-L2, PDCD1L2, PDL2, bA574F11.2, programmed cell death 1 ligand 2
2508:
2435:
2006:
Zhang Y, Chung Y, Bishop C, Daugherty B, Chute H, Holst P, et al. (August 2006).
667:
662:
657:
652:
647:
642:
637:
632:
627:
622:
617:
612:
596:
591:
586:
581:
576:
571:
566:
550:
545:
5050:
4519:
3976:
3067:
2779:
2344:
Tseng SY, Otsuji M, Gorski K, Huang X, Slansky JE, Pai SI, et al. (April 2001).
1580:
Tseng SY, Otsuji M, Gorski K, Huang X, Slansky JE, Pai SI, et al. (April 2001).
1315:
1285:
1253:
1172:
1161:
1125:
532:
2816:
2680:
2610:
Ohigashi Y, Sho M, Yamada Y, Tsurui Y, Hamada K, Ikeda N, et al. (April 2005).
2524:
2486:
2291:
Obeid JM, Erdag G, Smolkin ME, Deacon DH, Patterson JW, Chen L, et al. (2016).
1825:
1563:
1454:
80:
4875:
4183:
4173:
3704:
3670:
2884:
2795:
1775:
1293:
1233:
1069:
338:
117:
2733:"No evidence of association between genetic variants of the PDCD1 ligands and SLE"
2628:
2611:
2308:
2240:
Tobin JW, Keane C, Gunawardana J, Mollee P, Birch S, Hoang T, et al. (2019).
2157:
2107:
2090:
1924:
1907:
1084:
with other B7 proteins, but it does not contain the putative binding sequence for
1852:
1809:
104:
4885:
4534:
4312:
4287:
3986:
3608:
3534:
3008:
2405:
2388:
1407:
National Center for
Biotechnology Information, U.S. National Library of Medicine
1389:
National Center for
Biotechnology Information, U.S. National Library of Medicine
1240:. Unlike PD-L1, PD-L2 has been shown activate the immune system. PD-L2 triggers
2012:
Proceedings of the
National Academy of Sciences of the United States of America
1954:"PD-L1 and PD-L2 differ in their molecular mechanisms of interaction with PD-1"
1906:
Yearley JH, Gibson C, Yu N, Moon C, Murphy E, Juco J, et al. (June 2017).
1686:
Proceedings of the
National Academy of Sciences of the United States of America
1635:
Proceedings of the
National Academy of Sciences of the United States of America
421:
4815:
4539:
4220:
3961:
3837:
3470:
3465:
3460:
3315:
3099:
1629:
Lázár-Molnár E, Yan Q, Cao E, Ramagopal U, Nathenson SG, Almo SC (July 2008).
1318:
independently of PD-L1 expression. However, PD-L2 does not putatively predict
1121:
237:
134:
84:
4654:
4649:
4644:
4634:
4629:
4624:
4619:
2749:
2732:
2550:
2533:
2207:
2032:
1969:
1908:"PD-L2 Expression in Human Tumors: Relevance to Anti-PD-1 Therapy in Cancer"
1791:"PD-L2 is expressed on activated human T cells and regulates their function"
1706:
1647:
1323:
1289:
697:
481:
359:
304:
291:
203:
190:
92:
2824:
2787:
2758:
2723:
2672:
2637:
2602:
2559:
2516:
2478:
2443:
2414:
2379:
2326:
2277:
2226:
2175:
2126:
2051:
1987:
1933:
1860:
1817:
1767:
1725:
1666:
1615:
1555:
1517:
1446:
2705:
2663:
2646:
2469:
2452:
2361:
1597:
1248:
leading to T cell activation. Others have shown that treatment with PD-L2
1132:. PD-L2 protein is widely expressed in many healthy tissues including the
999:
994:
4960:
4860:
4659:
3862:
3857:
3765:
3455:
2258:
1184:
1145:
983:
842:
823:
2584:
2534:"Cloning and identification of two novel splice variants of human PD-L2"
2117:
4910:
4905:
4900:
4800:
4614:
4604:
4431:
4410:
4405:
4373:
4178:
4098:
4093:
4088:
4083:
4078:
3996:
3689:
3529:
3524:
3519:
3514:
3509:
2980:
2880:
1096:
1015:
809:
764:
4850:
4810:
4795:
4779:
4774:
4754:
4749:
4684:
4492:
4462:
4426:
4417:
4230:
4198:
4062:
4057:
4027:
4006:
3966:
3926:
3792:
3770:
3729:
3653:
3648:
3643:
3638:
3633:
3628:
3497:
3492:
3487:
3435:
3420:
3290:
3280:
3243:
3238:
3156:
3151:
2923:
1789:
Messal N, Serriari NE, Pastor S, Nunès JA, Olive D (September 2011).
1499:
1277:
1224:-mediated immune cell activation (for a more detailed discussion see
1141:
1085:
967:
719:
17:
1547:
1296:). There are still no FDA approved inhibitors for PD-L2 as of 2019.
2140:
Wang ZL, Li GZ, Wang QW, Bao ZS, Wang Z, Zhang CB, Jiang T (2019).
1759:
4975:
4950:
4870:
4865:
4855:
4845:
4830:
4825:
4820:
4805:
4759:
4744:
4709:
4694:
4689:
4679:
4599:
4594:
4589:
4568:
4564:
4554:
4467:
4368:
4363:
4322:
4272:
4267:
4262:
4257:
4242:
4235:
4215:
4203:
4146:
4141:
4136:
4126:
4121:
4114:
4052:
4042:
4037:
4032:
4022:
4001:
3991:
3956:
3951:
3946:
3941:
3936:
3891:
3886:
3852:
3817:
3812:
3807:
3797:
3785:
3780:
3760:
3755:
3750:
3745:
3699:
3591:
3586:
3405:
3389:
3382:
3377:
3372:
3367:
3362:
3357:
3332:
3310:
3305:
3198:
3124:
3119:
3109:
2933:
2928:
2918:
2645:
Saunders PA, Hendrycks VR, Lidinsky WA, Woods ML (December 2005).
1438:
1265:
1052:
1037:
receptor ligand which plays a role in negative regulation of the
682:
678:
4970:
4965:
4955:
4945:
4940:
4935:
4890:
4880:
4840:
4769:
4739:
4734:
4729:
4724:
4719:
4714:
4669:
4639:
4544:
4512:
4507:
4487:
4477:
4472:
4457:
4452:
4353:
4348:
4317:
4297:
4292:
4282:
4277:
4156:
4109:
4069:
3724:
3719:
3714:
3709:
3694:
3685:
3680:
3675:
3660:
3618:
3613:
3603:
3598:
3581:
3576:
3571:
3566:
3561:
3556:
3551:
3546:
3541:
3477:
3450:
3445:
3440:
3415:
3410:
3347:
3342:
3337:
3327:
3322:
3275:
3270:
3265:
3255:
3250:
3233:
3228:
3223:
3213:
3208:
3193:
3188:
3183:
3173:
3168:
3163:
3146:
3141:
3136:
3087:
3055:
3050:
3045:
3028:
3023:
3018:
3013:
2908:
2903:
1022:
512:
72:
2953:
2853:
1164:
is widely expressed and not enriched in any particular tissue.
4482:
3094:
3082:
3077:
3072:
3062:
3035:
3003:
1326:
and other studies suggesting it predicts positive prognoses.
1322:
in cancer, with some studies suggesting it predicts negative
1216:
of 11.3 nM. Binding to PD-1 can activate pathways inhibiting
2066:"Search of: PDCD1LG2 - List Results - ClinicalTrials.gov"
1148:. Additionally, PD-L2 has moderate to high expression in
1469:"Entrez Gene: PDCD1LG2 programmed cell death 1 ligand 2"
328:
5011:
2008:"Regulation of T cell activation and tolerance by PDL2"
613:
negative regulation of activated T cell proliferation
493:
4788:
4582:
4331:
4015:
3738:
3398:
2996:
2896:
2424:
1299:The direct role of PD-L2 in cancer progression and
928:
907:
881:
860:
1363:
1361:
1359:
1342:
1340:
1338:
1200:induce moderate upregulation of PD-L2 expression.
633:negative regulation of interferon-gamma production
275:
174:
1177:granulocyte-macrophage colony stimulating factor
1124:. Others have shown PD-L2 expression in certain
1041:response. PD-L2 is one of two known ligands for
623:negative regulation of interleukin-10 production
27:Protein-coding gene in the species Homo sapiens
1484:"PD-1 as a potential target in cancer therapy"
1420:
1418:
1416:
1368:GRCm38: Ensembl release 89: ENSMUSG00000016498
5031:
2965:
2865:
1112:PD-L2 is primarily expressed on professional
8:
1179:(GMCSF) both upregulate PD-L2 expression in
2532:He XH, Liu Y, Xu LH, Zeng YY (April 2004).
1347:GRCh38: Ensembl release 89: ENSG00000197646
643:positive regulation of T cell proliferation
628:negative regulation of T cell proliferation
5038:
5024:
2972:
2958:
2950:
2872:
2858:
2850:
693:
528:
316:
215:
112:
2989:list of human clusters of differentiation
2842:at the U.S. National Library of Medicine
2748:
2713:
2662:
2627:
2592:
2549:
2468:
2404:
2369:
2316:
2267:
2257:
2216:
2206:
2165:
2116:
2106:
2041:
2031:
1977:
1923:
1715:
1705:
1656:
1646:
1605:
1507:
1238:experimental autoimmune encephalomyelitis
2768:The American Journal of Gastroenterology
1482:McDermott DF, Atkins MB (October 2013).
1310:Indirectly, PD-L2 may have utility as a
1334:
1280:. Due to their role in suppressing the
1025:. PDCD1LG2 has also been designated as
658:cellular response to lipopolysaccharide
653:cell surface receptor signaling pathway
1208:PD-L2 binds to its receptor PD-1 with
29:
2189:Yang H, Zhou X, Sun L, Mao Y (2019).
2001:
1999:
1997:
1947:
1945:
1943:
1901:
1899:
1897:
1872:
1870:
1741:
1739:
1737:
1735:
280:
241:
236:
179:
138:
133:
7:
4992:
4990:
2538:Acta Biochimica et Biophysica Sinica
2350:The Journal of Experimental Medicine
1586:The Journal of Experimental Medicine
1575:
1573:
1529:
1527:
1228:). PD-L2 plays an important role in
2567:Zhang Z, Henzel WJ (October 2004).
1078:immunoglobulin-like constant domain
1074:immunoglobulin-like variable domain
5010:. You can help Knowledge (XXG) by
1014:(also known as PD-L2, B7-DC) is a
925:
904:
878:
857:
833:
814:
788:
769:
743:
724:
498:
416:
354:
333:
25:
2509:10.1097/01.TP.0000108637.65091.4B
1272:expressions are important in the
1018:that in humans is encoded by the
4994:
2780:10.1111/j.1572-0241.2006.00948.x
1680:Tang S, Kim PS (December 2019).
1088:, namely SQDXXXELY or XXXYXXRT.
1012:Programmed cell death 1 ligand 2
592:external side of plasma membrane
502:
264:
257:
251:
228:
163:
156:
150:
125:
1878:"Tissue expression of PDCD1LG2"
1043:Programmed cell death protein 1
2694:European Journal of Immunology
2651:European Journal of Immunology
2457:European Journal of Immunology
567:integral component of membrane
513:More reference expression data
482:More reference expression data
1:
2817:10.1093/rheumatology/34.8.721
2629:10.1158/1078-0432.CCR-04-1469
2436:10.1016/S0006-291X(03)01257-9
2309:10.1080/2162402X.2016.1235107
2158:10.1080/2162402X.2018.1541535
2108:10.1158/1078-0432.CCR-18-3991
1925:10.1158/1078-0432.CCR-16-1761
1301:immune-tumor microenvironment
1150:triple-negative breast cancer
249:
148:
2246:Journal of Clinical Oncology
1853:10.1016/j.molimm.2011.09.014
1810:10.1016/j.molimm.2011.06.436
1307:-mediated immune responses.
5062:Clusters of differentiation
5057:Genes on human chromosome 9
2985:clusters of differentiation
2805:The Journal of Rheumatology
2406:10.4049/jimmunol.170.3.1257
370:stromal cell of endometrium
5083:
4989:
2889:immunoglobulin superfamily
1536:Nature Reviews. Immunology
1031:cluster of differentiation
1403:"Mouse PubMed Reference:"
1385:"Human PubMed Reference:"
1072:. It consists of both an
998:
993:
989:
982:
966:
947:
932:
911:
900:
885:
864:
853:
840:
836:
821:
817:
808:
795:
791:
776:
772:
763:
750:
746:
731:
727:
718:
703:
696:
692:
676:
531:
527:
510:
501:
492:
479:
428:
419:
366:
357:
327:
319:
315:
298:
285:
248:
227:
218:
214:
197:
184:
147:
124:
115:
111:
66:
63:
53:
46:
41:
37:
32:
2844:Medical Subject Headings
2616:Clinical Cancer Research
2095:Clinical Cancer Research
1958:International Immunology
1912:Clinical Cancer Research
1114:antigen presenting cells
960:Chr 19: 29.39 – 29.45 Mb
663:adaptive immune response
2840:PDCD1LG2+protein,+human
2750:10.1038/sj.gene.6364360
2208:10.3389/fonc.2019.00047
2033:10.1073/pnas.0601347103
1882:The Human Protein Atlas
1707:10.1073/pnas.1916916116
1648:10.1073/pnas.0804453105
402:upper lobe of left lung
5067:Membrane protein stubs
5006:–related article is a
1282:adaptive immune system
1156:and low expression in
1061:
452:lumbar spinal ganglion
448:mesenteric lymph nodes
2706:10.1002/eji.200535344
2664:10.1002/eji.200526347
2551:10.1093/abbs/36.4.284
2470:10.1002/eji.200324084
2393:Journal of Immunology
2362:10.1084/jem.193.7.839
2195:Frontiers in Oncology
1970:10.1093/intimm/dxq049
1598:10.1084/jem.193.7.839
1260:Clinical significance
1244:production in murine
1210:dissociation constant
1066:cell surface receptor
1058:X-ray crystallography
1056:
1033:273). PDCD1LG2 is an
953:Chr 9: 5.51 – 5.57 Mb
668:immune system process
243:Chromosome 19 (mouse)
2259:10.1200/JCO.18.02365
1841:Molecular Immunology
1798:Molecular Immunology
1158:renal cell carcinoma
618:T cell costimulation
572:extracellular region
398:smooth muscle tissue
141:Chromosome 9 (human)
105:PDCD1LG2 - orthologs
2585:10.1110/ps.04682504
2024:2006PNAS..10311695Z
1698:2019PNAS..11624500T
1692:(49): 24500–24506.
648:signal transduction
577:endomembrane system
440:submandibular gland
2737:Genes and Immunity
2070:clinicaltrials.gov
1062:
798:ENSMUSG00000016498
606:Biological process
560:Cellular component
546:molecular function
539:Molecular function
456:tibiofemoral joint
5019:
5018:
4984:
4983:
2947:
2946:
2252:(34): 3300–3309.
2101:(15): 4808–4819.
2018:(31): 11695–700.
1918:(12): 3158–3167.
1804:(15–16): 2214–9.
1748:Nature Immunology
1427:Nature Immunology
1130:cytotoxic T cells
1093:crystal structure
1082:sequence homology
1070:B7 protein family
1068:belonging to the
1035:immune checkpoint
1009:
1008:
1005:
1004:
978:
977:
943:
942:
922:
921:
896:
895:
875:
874:
849:
848:
830:
829:
804:
803:
785:
784:
759:
758:
740:
739:
688:
687:
523:
522:
519:
518:
488:
487:
475:
474:
413:
412:
311:
310:
210:
209:
16:(Redirected from
5074:
5040:
5033:
5026:
5004:membrane protein
4998:
4991:
2974:
2967:
2960:
2951:
2874:
2867:
2860:
2851:
2828:
2799:
2762:
2752:
2727:
2717:
2684:
2666:
2641:
2631:
2606:
2596:
2563:
2553:
2528:
2490:
2472:
2447:
2418:
2408:
2383:
2373:
2331:
2330:
2320:
2303:(11): e1235107.
2288:
2282:
2281:
2271:
2261:
2237:
2231:
2230:
2220:
2210:
2186:
2180:
2179:
2169:
2137:
2131:
2130:
2120:
2110:
2086:
2080:
2079:
2077:
2076:
2062:
2056:
2055:
2045:
2035:
2003:
1992:
1991:
1981:
1949:
1938:
1937:
1927:
1903:
1892:
1891:
1889:
1888:
1874:
1865:
1864:
1836:
1830:
1829:
1795:
1786:
1780:
1779:
1743:
1730:
1729:
1719:
1709:
1677:
1671:
1670:
1660:
1650:
1626:
1620:
1619:
1609:
1577:
1568:
1567:
1531:
1522:
1521:
1511:
1500:10.1002/cam4.106
1479:
1473:
1472:
1465:
1459:
1458:
1422:
1411:
1410:
1399:
1393:
1392:
1381:
1375:
1365:
1354:
1344:
1305:cytotoxic T cell
1230:immune tolerance
1138:skeletal muscles
991:
990:
962:
955:
938:
926:
917:
905:
901:RefSeq (protein)
891:
879:
870:
858:
834:
815:
789:
770:
744:
725:
694:
529:
515:
506:
499:
484:
424:
422:Top expressed in
417:
362:
360:Top expressed in
355:
334:
317:
307:
294:
283:
268:
261:
255:
244:
232:
216:
206:
193:
182:
167:
160:
154:
143:
129:
113:
107:
58:
51:
30:
21:
5082:
5081:
5077:
5076:
5075:
5073:
5072:
5071:
5047:
5046:
5045:
5044:
4987:
4985:
4980:
4784:
4578:
4327:
4011:
3734:
3394:
2992:
2978:
2948:
2943:
2892:
2878:
2836:
2831:
2802:
2765:
2730:
2687:
2644:
2609:
2579:(10): 2819–24.
2573:Protein Science
2566:
2531:
2497:Transplantation
2493:
2463:(10): 2773–82.
2450:
2421:
2386:
2343:
2339:
2337:Further reading
2334:
2290:
2289:
2285:
2239:
2238:
2234:
2188:
2187:
2183:
2152:(2): e1541535.
2139:
2138:
2134:
2088:
2087:
2083:
2074:
2072:
2064:
2063:
2059:
2005:
2004:
1995:
1951:
1950:
1941:
1905:
1904:
1895:
1886:
1884:
1876:
1875:
1868:
1838:
1837:
1833:
1793:
1788:
1787:
1783:
1745:
1744:
1733:
1679:
1678:
1674:
1641:(30): 10483–8.
1628:
1627:
1623:
1579:
1578:
1571:
1548:10.1038/nri1349
1533:
1532:
1525:
1488:Cancer Medicine
1481:
1480:
1476:
1467:
1466:
1462:
1424:
1423:
1414:
1401:
1400:
1396:
1383:
1382:
1378:
1366:
1357:
1345:
1336:
1332:
1274:immune response
1262:
1256:proliferation.
1246:dendritic cells
1215:
1206:
1170:
1118:dendritic cells
1110:
1105:
1051:
1039:adaptive immune
1000:View/Edit Mouse
995:View/Edit Human
958:
951:
948:Location (UCSC)
934:
913:
887:
866:
779:ENSG00000197646
672:
638:immune response
601:
587:plasma membrane
555:
551:protein binding
511:
480:
471:
466:
464:skin of abdomen
462:
458:
454:
450:
446:
442:
438:
434:
420:
409:
404:
400:
396:
392:
388:
384:
380:
378:Achilles tendon
376:
372:
358:
302:
289:
281:
271:
270:
269:
262:
242:
219:Gene location (
201:
188:
180:
170:
169:
168:
161:
139:
116:Gene location (
67:
54:
47:
28:
23:
22:
15:
12:
11:
5:
5080:
5078:
5070:
5069:
5064:
5059:
5049:
5048:
5043:
5042:
5035:
5028:
5020:
5017:
5016:
4999:
4982:
4981:
4979:
4978:
4973:
4968:
4963:
4958:
4953:
4948:
4943:
4938:
4933:
4928:
4923:
4918:
4913:
4908:
4903:
4898:
4893:
4888:
4883:
4878:
4873:
4868:
4863:
4858:
4853:
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4662:
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4510:
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4455:
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4435:
4429:
4420:
4415:
4414:
4413:
4408:
4398:
4393:
4392:
4391:
4386:
4376:
4371:
4366:
4361:
4356:
4351:
4346:
4341:
4335:
4333:
4329:
4328:
4326:
4325:
4320:
4315:
4310:
4305:
4300:
4295:
4290:
4285:
4280:
4275:
4270:
4265:
4260:
4255:
4250:
4245:
4240:
4239:
4238:
4233:
4223:
4218:
4213:
4208:
4207:
4206:
4201:
4196:
4186:
4181:
4176:
4171:
4166:
4165:
4164:
4159:
4149:
4144:
4139:
4134:
4129:
4124:
4119:
4118:
4117:
4112:
4102:
4096:
4091:
4086:
4081:
4072:
4067:
4066:
4065:
4060:
4055:
4045:
4040:
4035:
4030:
4025:
4019:
4017:
4013:
4012:
4010:
4009:
4004:
3999:
3994:
3989:
3984:
3979:
3974:
3969:
3964:
3959:
3954:
3949:
3944:
3939:
3934:
3929:
3924:
3919:
3914:
3909:
3904:
3899:
3894:
3889:
3884:
3883:
3882:
3877:
3867:
3866:
3865:
3860:
3850:
3845:
3840:
3835:
3830:
3825:
3820:
3815:
3810:
3805:
3800:
3795:
3790:
3789:
3788:
3783:
3773:
3768:
3763:
3758:
3753:
3748:
3742:
3740:
3736:
3735:
3733:
3732:
3727:
3722:
3717:
3712:
3707:
3702:
3697:
3692:
3683:
3678:
3673:
3668:
3663:
3658:
3657:
3656:
3651:
3646:
3641:
3636:
3631:
3621:
3616:
3611:
3606:
3601:
3596:
3595:
3594:
3589:
3579:
3574:
3569:
3564:
3559:
3554:
3549:
3544:
3539:
3538:
3537:
3532:
3527:
3522:
3517:
3512:
3502:
3501:
3500:
3495:
3490:
3480:
3475:
3474:
3473:
3468:
3463:
3453:
3448:
3443:
3438:
3433:
3428:
3423:
3418:
3413:
3408:
3402:
3400:
3396:
3395:
3393:
3392:
3387:
3386:
3385:
3380:
3375:
3370:
3365:
3360:
3350:
3345:
3340:
3335:
3330:
3325:
3320:
3319:
3318:
3313:
3308:
3303:
3293:
3288:
3283:
3278:
3273:
3268:
3263:
3258:
3253:
3248:
3247:
3246:
3241:
3231:
3226:
3221:
3216:
3211:
3206:
3201:
3196:
3191:
3186:
3181:
3176:
3171:
3166:
3161:
3160:
3159:
3154:
3144:
3139:
3134:
3129:
3128:
3127:
3122:
3117:
3112:
3102:
3097:
3092:
3091:
3090:
3080:
3075:
3070:
3065:
3060:
3059:
3058:
3053:
3048:
3038:
3033:
3032:
3031:
3026:
3021:
3016:
3011:
3000:
2998:
2994:
2993:
2979:
2977:
2976:
2969:
2962:
2954:
2945:
2944:
2942:
2941:
2936:
2931:
2926:
2921:
2916:
2911:
2906:
2900:
2898:
2894:
2893:
2879:
2877:
2876:
2869:
2862:
2854:
2848:
2847:
2835:
2834:External links
2832:
2830:
2829:
2800:
2763:
2728:
2700:(5): 1104–13.
2685:
2657:(12): 3561–9.
2642:
2622:(8): 2947–53.
2607:
2564:
2529:
2491:
2448:
2419:
2399:(3): 1257–66.
2384:
2340:
2338:
2335:
2333:
2332:
2297:Oncoimmunology
2283:
2232:
2181:
2146:Oncoimmunology
2132:
2081:
2057:
1993:
1939:
1893:
1866:
1831:
1781:
1760:10.1038/ni1443
1731:
1672:
1621:
1569:
1523:
1474:
1460:
1412:
1394:
1376:
1355:
1333:
1331:
1328:
1261:
1258:
1226:PD-1 signaling
1213:
1205:
1202:
1169:
1166:
1154:gastric cancer
1109:
1106:
1104:
1101:
1050:
1047:
1007:
1006:
1003:
1002:
997:
987:
986:
980:
979:
976:
975:
973:
971:
964:
963:
956:
949:
945:
944:
941:
940:
930:
929:
923:
920:
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902:
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893:
883:
882:
876:
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561:
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469:
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414:
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391:
387:
383:
379:
375:
371:
367:
364:
363:
351:
350:
342:
331:
325:
324:
321:RNA expression
313:
312:
309:
308:
300:
296:
295:
287:
284:
279:
273:
272:
263:
256:
250:
246:
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109:
108:
65:
61:
60:
52:
44:
43:
39:
38:
35:
34:
26:
24:
14:
13:
10:
9:
6:
4:
3:
2:
5079:
5068:
5065:
5063:
5060:
5058:
5055:
5054:
5052:
5041:
5036:
5034:
5029:
5027:
5022:
5021:
5015:
5013:
5009:
5005:
5000:
4997:
4993:
4988:
4977:
4974:
4972:
4969:
4967:
4964:
4962:
4959:
4957:
4954:
4952:
4949:
4947:
4944:
4942:
4939:
4937:
4934:
4932:
4929:
4927:
4924:
4922:
4919:
4917:
4914:
4912:
4909:
4907:
4904:
4902:
4899:
4897:
4894:
4892:
4889:
4887:
4884:
4882:
4879:
4877:
4874:
4872:
4869:
4867:
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4862:
4859:
4857:
4854:
4852:
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4842:
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4829:
4827:
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4771:
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4751:
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4726:
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4711:
4708:
4706:
4703:
4701:
4698:
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4693:
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4688:
4686:
4683:
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4678:
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4309:
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4301:
4299:
4296:
4294:
4291:
4289:
4286:
4284:
4281:
4279:
4276:
4274:
4271:
4269:
4266:
4264:
4261:
4259:
4256:
4254:
4251:
4249:
4246:
4244:
4241:
4237:
4234:
4232:
4229:
4228:
4227:
4224:
4222:
4219:
4217:
4214:
4212:
4209:
4205:
4202:
4200:
4197:
4195:
4192:
4191:
4190:
4187:
4185:
4182:
4180:
4177:
4175:
4172:
4170:
4167:
4163:
4160:
4158:
4155:
4154:
4153:
4150:
4148:
4145:
4143:
4140:
4138:
4135:
4133:
4130:
4128:
4125:
4123:
4120:
4116:
4113:
4111:
4108:
4107:
4106:
4103:
4100:
4097:
4095:
4092:
4090:
4087:
4085:
4082:
4080:
4076:
4073:
4071:
4068:
4064:
4061:
4059:
4056:
4054:
4051:
4050:
4049:
4046:
4044:
4041:
4039:
4036:
4034:
4031:
4029:
4026:
4024:
4021:
4020:
4018:
4014:
4008:
4005:
4003:
4000:
3998:
3995:
3993:
3990:
3988:
3985:
3983:
3980:
3978:
3975:
3973:
3970:
3968:
3965:
3963:
3960:
3958:
3955:
3953:
3950:
3948:
3945:
3943:
3940:
3938:
3935:
3933:
3930:
3928:
3925:
3923:
3920:
3918:
3915:
3913:
3910:
3908:
3905:
3903:
3900:
3898:
3895:
3893:
3890:
3888:
3885:
3881:
3878:
3876:
3873:
3872:
3871:
3868:
3864:
3861:
3859:
3856:
3855:
3854:
3851:
3849:
3846:
3844:
3841:
3839:
3836:
3834:
3831:
3829:
3826:
3824:
3821:
3819:
3816:
3814:
3811:
3809:
3806:
3804:
3801:
3799:
3796:
3794:
3791:
3787:
3784:
3782:
3779:
3778:
3777:
3774:
3772:
3769:
3767:
3764:
3762:
3759:
3757:
3754:
3752:
3749:
3747:
3744:
3743:
3741:
3737:
3731:
3728:
3726:
3723:
3721:
3718:
3716:
3713:
3711:
3708:
3706:
3703:
3701:
3698:
3696:
3693:
3691:
3687:
3684:
3682:
3679:
3677:
3674:
3672:
3669:
3667:
3664:
3662:
3659:
3655:
3652:
3650:
3647:
3645:
3642:
3640:
3637:
3635:
3632:
3630:
3627:
3626:
3625:
3622:
3620:
3617:
3615:
3612:
3610:
3607:
3605:
3602:
3600:
3597:
3593:
3590:
3588:
3585:
3584:
3583:
3580:
3578:
3575:
3573:
3570:
3568:
3565:
3563:
3560:
3558:
3555:
3553:
3550:
3548:
3545:
3543:
3540:
3536:
3533:
3531:
3528:
3526:
3523:
3521:
3518:
3516:
3513:
3511:
3508:
3507:
3506:
3503:
3499:
3496:
3494:
3491:
3489:
3486:
3485:
3484:
3481:
3479:
3476:
3472:
3469:
3467:
3464:
3462:
3459:
3458:
3457:
3454:
3452:
3449:
3447:
3444:
3442:
3439:
3437:
3434:
3432:
3429:
3427:
3424:
3422:
3419:
3417:
3414:
3412:
3409:
3407:
3404:
3403:
3401:
3397:
3391:
3388:
3384:
3381:
3379:
3376:
3374:
3371:
3369:
3366:
3364:
3361:
3359:
3356:
3355:
3354:
3351:
3349:
3346:
3344:
3341:
3339:
3336:
3334:
3331:
3329:
3326:
3324:
3321:
3317:
3314:
3312:
3309:
3307:
3304:
3302:
3299:
3298:
3297:
3294:
3292:
3289:
3287:
3284:
3282:
3279:
3277:
3274:
3272:
3269:
3267:
3264:
3262:
3259:
3257:
3254:
3252:
3249:
3245:
3242:
3240:
3237:
3236:
3235:
3232:
3230:
3227:
3225:
3222:
3220:
3217:
3215:
3212:
3210:
3207:
3205:
3202:
3200:
3197:
3195:
3192:
3190:
3187:
3185:
3182:
3180:
3177:
3175:
3172:
3170:
3167:
3165:
3162:
3158:
3155:
3153:
3150:
3149:
3148:
3145:
3143:
3140:
3138:
3135:
3133:
3130:
3126:
3123:
3121:
3118:
3116:
3113:
3111:
3108:
3107:
3106:
3103:
3101:
3098:
3096:
3093:
3089:
3086:
3085:
3084:
3081:
3079:
3076:
3074:
3071:
3069:
3066:
3064:
3061:
3057:
3054:
3052:
3049:
3047:
3044:
3043:
3042:
3039:
3037:
3034:
3030:
3027:
3025:
3022:
3020:
3017:
3015:
3012:
3010:
3007:
3006:
3005:
3002:
3001:
2999:
2995:
2990:
2986:
2982:
2975:
2970:
2968:
2963:
2961:
2956:
2955:
2952:
2940:
2937:
2935:
2932:
2930:
2927:
2925:
2922:
2920:
2917:
2915:
2912:
2910:
2907:
2905:
2902:
2901:
2899:
2895:
2890:
2886:
2882:
2875:
2870:
2868:
2863:
2861:
2856:
2855:
2852:
2845:
2841:
2838:
2837:
2833:
2826:
2822:
2818:
2814:
2810:
2806:
2801:
2797:
2793:
2789:
2785:
2781:
2777:
2774:(2): 302–12.
2773:
2769:
2764:
2760:
2756:
2751:
2746:
2742:
2738:
2734:
2729:
2725:
2721:
2716:
2711:
2707:
2703:
2699:
2695:
2691:
2686:
2682:
2678:
2674:
2670:
2665:
2660:
2656:
2652:
2648:
2643:
2639:
2635:
2630:
2625:
2621:
2617:
2613:
2608:
2604:
2600:
2595:
2590:
2586:
2582:
2578:
2574:
2570:
2565:
2561:
2557:
2552:
2547:
2543:
2539:
2535:
2530:
2526:
2522:
2518:
2514:
2510:
2506:
2502:
2498:
2492:
2488:
2484:
2480:
2476:
2471:
2466:
2462:
2458:
2454:
2449:
2445:
2441:
2437:
2433:
2429:
2425:
2420:
2416:
2412:
2407:
2402:
2398:
2394:
2390:
2385:
2381:
2377:
2372:
2367:
2363:
2359:
2356:(7): 839–46.
2355:
2351:
2347:
2342:
2341:
2336:
2328:
2324:
2319:
2314:
2310:
2306:
2302:
2298:
2294:
2287:
2284:
2279:
2275:
2270:
2265:
2260:
2255:
2251:
2247:
2243:
2236:
2233:
2228:
2224:
2219:
2214:
2209:
2204:
2200:
2196:
2192:
2185:
2182:
2177:
2173:
2168:
2163:
2159:
2155:
2151:
2147:
2143:
2136:
2133:
2128:
2124:
2119:
2114:
2109:
2104:
2100:
2096:
2092:
2085:
2082:
2071:
2067:
2061:
2058:
2053:
2049:
2044:
2039:
2034:
2029:
2025:
2021:
2017:
2013:
2009:
2002:
2000:
1998:
1994:
1989:
1985:
1980:
1975:
1971:
1967:
1964:(8): 651–60.
1963:
1959:
1955:
1948:
1946:
1944:
1940:
1935:
1931:
1926:
1921:
1917:
1913:
1909:
1902:
1900:
1898:
1894:
1883:
1879:
1873:
1871:
1867:
1862:
1858:
1854:
1850:
1846:
1842:
1835:
1832:
1827:
1823:
1819:
1815:
1811:
1807:
1803:
1799:
1792:
1785:
1782:
1777:
1773:
1769:
1765:
1761:
1757:
1754:(3): 239–45.
1753:
1749:
1742:
1740:
1738:
1736:
1732:
1727:
1723:
1718:
1713:
1708:
1703:
1699:
1695:
1691:
1687:
1683:
1676:
1673:
1668:
1664:
1659:
1654:
1649:
1644:
1640:
1636:
1632:
1625:
1622:
1617:
1613:
1608:
1603:
1599:
1595:
1592:(7): 839–46.
1591:
1587:
1583:
1576:
1574:
1570:
1565:
1561:
1557:
1553:
1549:
1545:
1542:(5): 336–47.
1541:
1537:
1530:
1528:
1524:
1519:
1515:
1510:
1505:
1501:
1497:
1494:(5): 662–73.
1493:
1489:
1485:
1478:
1475:
1470:
1464:
1461:
1456:
1452:
1448:
1444:
1440:
1439:10.1038/85330
1436:
1432:
1428:
1421:
1419:
1417:
1413:
1408:
1404:
1398:
1395:
1390:
1386:
1380:
1377:
1373:
1369:
1364:
1362:
1360:
1356:
1352:
1348:
1343:
1341:
1339:
1335:
1329:
1327:
1325:
1321:
1317:
1316:pembrolizumab
1313:
1308:
1306:
1302:
1297:
1295:
1291:
1287:
1286:pembrolizumab
1283:
1279:
1275:
1271:
1267:
1259:
1257:
1255:
1254:T helper cell
1251:
1247:
1243:
1239:
1235:
1231:
1227:
1223:
1219:
1211:
1203:
1201:
1199:
1195:
1191:
1187:
1186:
1182:
1178:
1174:
1173:Interleukin-4
1167:
1165:
1163:
1159:
1155:
1151:
1147:
1143:
1139:
1135:
1131:
1127:
1126:T helper cell
1123:
1119:
1115:
1107:
1102:
1100:
1098:
1094:
1089:
1087:
1083:
1079:
1075:
1071:
1067:
1059:
1055:
1048:
1046:
1044:
1040:
1036:
1032:
1028:
1024:
1021:
1017:
1013:
1001:
996:
992:
988:
985:
981:
974:
972:
969:
965:
961:
957:
954:
950:
946:
939:
937:
931:
927:
924:
918:
916:
910:
906:
903:
899:
892:
890:
884:
880:
877:
871:
869:
863:
859:
856:
854:RefSeq (mRNA)
852:
845:
844:
839:
835:
832:
826:
825:
820:
816:
813:
811:
807:
800:
799:
794:
790:
787:
781:
780:
775:
771:
768:
766:
762:
755:
754:
749:
745:
742:
736:
735:
730:
726:
723:
721:
717:
714:
711:
709:
706:
702:
699:
695:
691:
684:
680:
675:
669:
666:
664:
661:
659:
656:
654:
651:
649:
646:
644:
641:
639:
636:
634:
631:
629:
626:
624:
621:
619:
616:
614:
611:
610:
608:
605:
604:
598:
595:
593:
590:
588:
585:
583:
580:
578:
575:
573:
570:
568:
565:
564:
562:
559:
558:
552:
549:
547:
544:
543:
541:
538:
537:
534:
533:Gene ontology
530:
526:
514:
509:
505:
500:
497:
495:
491:
483:
478:
467:
463:
459:
455:
451:
447:
443:
439:
435:
431:
430:
427:
423:
418:
415:
405:
401:
397:
393:
389:
385:
381:
377:
373:
369:
368:
365:
361:
356:
353:
352:
349:
347:
343:
341:
340:
336:
335:
332:
330:
326:
322:
318:
314:
306:
301:
297:
293:
288:
282:19|19 C1
278:
274:
267:
260:
254:
247:
239:
235:
231:
226:
222:
217:
213:
205:
200:
196:
192:
187:
177:
173:
166:
159:
153:
146:
142:
136:
132:
128:
123:
119:
114:
110:
106:
102:
98:
94:
90:
86:
82:
78:
74:
70:
62:
57:
50:
45:
40:
36:
31:
19:
5012:expanding it
5001:
4986:
4674:
4502:
4422:
4400:
4378:
4225:
4188:
4151:
4104:
4074:
4047:
3869:
3775:
3623:
3352:
3104:
2913:
2811:(4): 721–5.
2808:
2804:
2771:
2767:
2743:(1): 69–74.
2740:
2736:
2697:
2693:
2654:
2650:
2619:
2615:
2576:
2572:
2544:(4): 284–9.
2541:
2537:
2500:
2496:
2460:
2456:
2430:(3): 672–7.
2427:
2423:
2396:
2392:
2353:
2349:
2300:
2296:
2286:
2249:
2245:
2235:
2198:
2194:
2184:
2149:
2145:
2135:
2118:2324/4475014
2098:
2094:
2084:
2073:. Retrieved
2069:
2060:
2015:
2011:
1961:
1957:
1915:
1911:
1885:. Retrieved
1881:
1847:(1–2): 1–3.
1844:
1840:
1834:
1801:
1797:
1784:
1751:
1747:
1689:
1685:
1675:
1638:
1634:
1624:
1589:
1585:
1539:
1535:
1491:
1487:
1477:
1463:
1433:(3): 261–8.
1430:
1426:
1406:
1397:
1388:
1379:
1309:
1298:
1294:atezolizumab
1263:
1234:autoimmunity
1207:
1183:
1171:
1128:subsets and
1111:
1090:
1063:
1026:
1019:
1011:
1010:
933:
912:
886:
865:
841:
822:
796:
777:
751:
732:
712:
707:
597:cell surface
344:
337:
64:External IDs
2503:(1): 6–12.
1276:to certain
1175:(IL-4) and
1122:macrophages
1064:PD-L2 is a
394:gallbladder
303:29,448,561
290:29,388,319
42:Identifiers
5051:Categories
2987:(see also
2897:B7 ligands
2887:(see also
2075:2020-03-04
1887:2020-03-05
1374:, May 2017
1353:, May 2017
1330:References
1168:Regulation
1120:(DCs) and
1116:including
1103:Expression
1086:CD28/CTLA4
406:right lung
386:lymph node
348:(ortholog)
202:5,571,282
189:5,510,531
85:HomoloGene
2885:B7 family
1324:prognoses
1312:biomarker
1290:nivolumab
1136:tissues,
1049:Structure
936:NP_067371
915:NP_079515
889:NM_021396
868:NM_025239
698:Orthologs
93:GeneCards
2981:Proteins
2881:Proteins
2825:17343323
2788:17311651
2759:17136123
2724:16598819
2681:43876326
2673:16278812
2638:15837746
2603:15340161
2560:15253154
2525:25360886
2517:14724428
2487:34992725
2479:14515261
2444:12893276
2415:12538684
2380:11283156
2327:27999753
2278:31570492
2227:30891423
2176:30713802
2127:31076547
2052:16864790
1988:20587542
1934:28619999
1861:22000002
1826:33134166
1818:21752471
1768:17304234
1726:31727844
1667:18641123
1616:11283156
1564:33548210
1556:15122199
1518:24403232
1455:27659586
1447:11224527
1370:–
1349:–
1204:Function
1185:in vitro
1160:. PD-L2
1146:pancreas
1134:GI tract
1045:(PD-1).
1020:PDCD1LG2
984:Wikidata
677:Sources:
582:membrane
432:gastrula
382:appendix
374:testicle
97:PDCD1LG2
56:PDCD1LG2
33:PDCD1LG2
4789:301–350
4583:251–300
4535:CD240CE
4332:201–250
4016:151–200
3739:101–150
2796:8083797
2715:2975063
2594:2286551
2371:2193370
2318:5139635
2269:6784528
2218:6413700
2167:6343813
2043:1544232
2020:Bibcode
1979:3168865
1776:8749576
1717:6900541
1694:Bibcode
1658:2492495
1607:2193370
1509:3892798
1372:Ensembl
1351:Ensembl
1320:outcome
1278:cancers
1264:PD-L2,
1252:led to
1142:tonsils
1108:Profile
1076:and an
1016:protein
810:UniProt
765:Ensembl
704:Species
683:QuickGO
323:pattern
81:1930125
49:Aliases
4796:CD300A
4755:CDw293
4540:CD240D
4401:CD213a
4379:CDw210
4344:CD202b
4318:CDw199
4313:CDw198
3967:CD140b
3399:51–100
2846:(MeSH)
2823:
2794:
2786:
2757:
2722:
2712:
2679:
2671:
2636:
2601:
2591:
2558:
2523:
2515:
2485:
2477:
2442:
2413:
2378:
2368:
2325:
2315:
2276:
2266:
2225:
2215:
2201:: 47.
2174:
2164:
2125:
2050:
2040:
1986:
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