242:
219:
1043:
116:
141:
493:
4985:
248:
147:
2483:
Aramaki O, Shirasugi N, Takayama T, Shimazu M, Kitajima M, Ikeda Y, et al. (January 2004). "Programmed death-1-programmed death-L1 interaction is essential for induction of regulatory cells by intratracheal delivery of alloantigen".
3821:
2960:
2755:
Mataki N, Kikuchi K, Kawai T, Higashiyama M, Okada Y, Kurihara C, et al. (February 2007). "Expression of PD-1, PD-L1, and PD-L2 in the liver in autoimmune liver diseases".
255:
154:
1165:
5026:
2792:
Wang SC, Lin CH, Ou TT, Wu CC, Tsai WC, Hu CJ, et al. (April 2007). "Ligands for programmed cell death 1 gene in patients with systemic lupus erythematosus".
3811:
1414:
Latchman Y, Wood CR, Chernova T, Chaudhary D, Borde M, Chernova I, et al. (March 2001). "PD-L2 is a second ligand for PD-1 and inhibits T cell activation".
2411:
Youngnak P, Kozono Y, Kozono H, Iwai H, Otsuki N, Jin H, et al. (August 2003). "Differential binding properties of B7-H1 and B7-DC to programmed death-1".
1735:
Sharpe AH, Wherry EJ, Ahmed R, Freeman GJ (March 2007). "The function of programmed cell death 1 and its ligands in regulating autoimmunity and infection".
3791:
741:
722:
77:
4653:
2977:
2953:
1226:
4384:
1049:
structure of high affinity mutant hPDL2-hPD1 complex (1.986 Å) reported in Tang and Kim, PNAS 2019. hPD-1: green/blue, hPD-L2: red/orange/yellow
4372:
4150:
4436:
4431:
4377:
4157:
2938:
1391:
1373:
5050:
5045:
3890:
3816:
2946:
2054:
1225:. Both PD-L1 and PD-L2 can inhibit T cell proliferation and inflammatory cytokine production. Blocking PD-L2 has been shown to exacerbate
241:
5019:
4919:
4914:
4909:
4904:
3831:
2860:
948:
218:
4884:
941:
1457:
4120:
2442:"Preferential contribution of B7-H1 to programmed death-1-mediated regulation of hapten-specific allergic inflammatory responses"
2131:"PD-L2 expression is correlated with the molecular and clinical features of glioma, and acts as an unfavorable prognostic factor"
2282:"PD-L1, PD-L2 and PD-1 expression in metastatic melanoma: Correlation with tumor-infiltrating immune cells and clinical outcome"
5055:
4688:
4182:
3868:
1360:
1339:
1258:
1214:
1031:
5012:
4327:
3863:
2601:"Clinical significance of programmed death-1 ligand-1 and programmed death-1 ligand-2 expression in human esophageal cancer"
2231:"Progression of Disease Within 24 Months in Follicular Lymphoma Is Associated With Reduced Intratumoral Immune Infiltration"
1356:
1292:
regulation is not as well studied as the role of PD-L1. In mouse cell cultures, PD-L2 expression on tumor cells suppressed
140:
115:
4824:
4296:
4291:
4236:
3970:
3419:
1138:
1042:
1335:
4518:
4241:
254:
153:
57:
3836:
2679:"No evidence for dualism in function and receptors: PD-L2/B7-DC is an inhibitory regulator of human T cell activation"
247:
146:
4548:
2973:
2877:
1066:
1062:
1019:
2720:
Abelson AK, Johansson CM, Kozyrev SV, Kristjansdottir H, Gunnarsson I, Svenungsson E, et al. (January 2007).
3414:
4598:
3493:
2832:
786:
65:
2378:"Blockade of programmed death-1 ligands on dendritic cells enhances T cell activation and cytokine production"
1671:"A high-affinity human PD-1/PD-L2 complex informs avenues for small-molecule immune checkpoint drug discovery"
1088:
PD-L2 bound to murine PD-1 has been determined. as well as the structure of the hPD-L2/mutant hPD-1 complex.
4562:
2853:
2838:
1102:
767:
3905:
3900:
3895:
3885:
3192:
3120:
1289:
1270:
1122:
1027:
1069:
in the extracellular region, a transmembrane domain, and a cytoplasmic domain. PD-L2 shares considerable
3249:
3167:
1198:
1081:
1054:
1046:
1779:
1523:
Chen L (May 2004). "Co-inhibitory molecules of the B7-CD28 family in the control of T-cell immunity".
4486:
4199:
2828:
2636:"PD-L2:PD-1 involvement in T cell proliferation, cytokine production, and integrin-mediated adhesion"
2180:"Correlation Between PD-L2 Expression and Clinical Outcome in Solid Cancer Patients: A Meta-Analysis"
2008:
1682:
1300:
1273:, efforts have been made to block PD-1 and PD-L1, resulting in FDA approved inhibitors for both (see
1146:
129:
44:
4513:
4332:
1303:
or prognostic indicator. PD-L2 expression has been shown to predict response to PD-1 blockade with
2078:
Tanegashima T, Togashi Y, Azuma K, Kawahara A, Ideguchi K, Sugiyama D, et al. (August 2019).
492:
3920:
3654:
2846:
2780:
2677:
Pfistershammer K, Klauser C, Pickl WF, Stöckl J, Leitner J, Zlabinger G, et al. (May 2006).
2665:
2509:
2471:
1828:
Lesterhuis WJ, Steer H, Lake RA (October 2011). "PD-L2 is predominantly expressed by Th2 cells".
1810:
1760:
1548:
1439:
89:
924:
903:
877:
856:
1866:
2809:
2772:
2743:
2708:
2657:
2622:
2587:
2544:
2501:
2463:
2428:
2399:
2364:
2311:
2262:
2211:
2160:
2111:
2036:
1972:
1918:
1845:
1802:
1752:
1710:
1651:
1600:
1540:
1502:
1431:
1182:
1178:
1070:
1023:
85:
37:
4996:
4992:
4984:
4693:
4426:
4347:
3910:
3103:
3029:
2801:
2764:
2733:
2698:
2690:
2647:
2612:
2577:
2569:
2534:
2493:
2453:
2420:
2389:
2354:
2346:
2301:
2293:
2252:
2242:
2201:
2191:
2150:
2142:
2101:
2091:
2026:
2016:
1962:
1954:
1908:
1837:
1794:
1744:
1700:
1690:
1641:
1631:
1590:
1582:
1532:
1492:
1484:
1423:
1308:
1293:
1218:
1186:
1118:
334:
265:
209:
164:
4753:
3289:
3284:
3207:
2927:
2080:"Immune Suppression by PD-L2 against Spontaneous and Treatment-Related Antitumor Immunity"
1262:
1210:
1206:
1126:
309:
2376:
Brown JA, Dorfman DM, Ma FR, Sullivan EL, Munoz O, Wood CR, et al. (February 2003).
1620:"Crystal structure of the complex between programmed death-1 (PD-1) and its ligand PD-L2"
2012:
1941:
Ghiotto M, Gauthier L, Serriari N, Pastor S, Truneh A, Nunès JA, Olive D (August 2010).
1686:
4538:
3960:
3471:
3274:
2703:
2678:
2582:
2558:"Signal peptide prediction based on analysis of experimentally verified cleavage sites"
2557:
2440:
Tsushima F, Iwai H, Otsuki N, Abe M, Hirose S, Yamazaki T, et al. (October 2003).
2359:
2335:"B7-DC, a new dendritic cell molecule with potent costimulatory properties for T cells"
2334:
2306:
2281:
2257:
2230:
2206:
2179:
2155:
2130:
2031:
1996:
1967:
1942:
1705:
1670:
1646:
1619:
1595:
1571:"B7-DC, a new dendritic cell molecule with potent costimulatory properties for T cells"
1570:
1497:
1472:
1238:
1234:
1230:
1169:
1142:
1106:
48:, B7DC, Btdc, CD273, PD-L2, PDCD1L2, PDL2, bA574F11.2, programmed cell death 1 ligand 2
2497:
2424:
1995:
Zhang Y, Chung Y, Bishop C, Daugherty B, Chute H, Holst P, et al. (August 2006).
656:
651:
646:
641:
636:
631:
626:
621:
616:
611:
606:
601:
585:
580:
575:
570:
565:
560:
555:
539:
534:
5039:
4508:
3965:
3056:
2768:
2333:
Tseng SY, Otsuji M, Gorski K, Huang X, Slansky JE, Pai SI, et al. (April 2001).
1569:
Tseng SY, Otsuji M, Gorski K, Huang X, Slansky JE, Pai SI, et al. (April 2001).
1304:
1274:
1242:
1161:
1150:
1114:
521:
2805:
2669:
2599:
Ohigashi Y, Sho M, Yamada Y, Tsurui Y, Hamada K, Ikeda N, et al. (April 2005).
2513:
2475:
2280:
Obeid JM, Erdag G, Smolkin ME, Deacon DH, Patterson JW, Chen L, et al. (2016).
1814:
1552:
1443:
69:
4864:
4172:
4162:
3693:
3659:
2873:
2784:
1764:
1282:
1222:
1058:
327:
106:
2722:"No evidence of association between genetic variants of the PDCD1 ligands and SLE"
2617:
2600:
2297:
2229:
Tobin JW, Keane C, Gunawardana J, Mollee P, Birch S, Hoang T, et al. (2019).
2146:
2096:
2079:
1913:
1896:
1073:
with other B7 proteins, but it does not contain the putative binding sequence for
1841:
1798:
93:
4874:
4523:
4301:
4276:
3975:
3597:
3523:
2997:
2394:
2377:
1396:
National Center for
Biotechnology Information, U.S. National Library of Medicine
1378:
National Center for
Biotechnology Information, U.S. National Library of Medicine
1229:. Unlike PD-L1, PD-L2 has been shown activate the immune system. PD-L2 triggers
2001:
Proceedings of the
National Academy of Sciences of the United States of America
1943:"PD-L1 and PD-L2 differ in their molecular mechanisms of interaction with PD-1"
1895:
Yearley JH, Gibson C, Yu N, Moon C, Murphy E, Juco J, et al. (June 2017).
1675:
Proceedings of the
National Academy of Sciences of the United States of America
1624:
Proceedings of the
National Academy of Sciences of the United States of America
410:
4804:
4528:
4209:
3950:
3826:
3459:
3454:
3449:
3304:
3088:
1618:
Lázár-Molnár E, Yan Q, Cao E, Ramagopal U, Nathenson SG, Almo SC (July 2008).
1307:
independently of PD-L1 expression. However, PD-L2 does not putatively predict
1110:
226:
123:
73:
4643:
4638:
4633:
4623:
4618:
4613:
4608:
2738:
2721:
2539:
2522:
2196:
2021:
1958:
1897:"PD-L2 Expression in Human Tumors: Relevance to Anti-PD-1 Therapy in Cancer"
1780:"PD-L2 is expressed on activated human T cells and regulates their function"
1695:
1636:
1312:
1278:
686:
470:
348:
293:
280:
192:
179:
81:
2813:
2776:
2747:
2712:
2661:
2626:
2591:
2548:
2505:
2467:
2432:
2403:
2368:
2315:
2266:
2215:
2164:
2115:
2040:
1976:
1922:
1849:
1806:
1756:
1714:
1655:
1604:
1544:
1506:
1435:
2694:
2652:
2635:
2458:
2441:
2350:
1586:
1237:
leading to T cell activation. Others have shown that treatment with PD-L2
1121:. PD-L2 protein is widely expressed in many healthy tissues including the
988:
983:
4949:
4849:
4648:
3851:
3846:
3754:
3444:
2247:
1173:
1134:
972:
831:
812:
2573:
2523:"Cloning and identification of two novel splice variants of human PD-L2"
2106:
4899:
4894:
4889:
4789:
4603:
4593:
4420:
4399:
4394:
4362:
4167:
4087:
4082:
4077:
4072:
4067:
3985:
3678:
3518:
3513:
3508:
3503:
3498:
2969:
2869:
1085:
1004:
798:
753:
4839:
4799:
4784:
4768:
4763:
4743:
4738:
4673:
4481:
4451:
4415:
4406:
4219:
4187:
4051:
4046:
4016:
3995:
3955:
3915:
3781:
3759:
3718:
3642:
3637:
3632:
3627:
3622:
3617:
3486:
3481:
3476:
3424:
3409:
3279:
3269:
3232:
3227:
3145:
3140:
2912:
1778:
Messal N, Serriari NE, Pastor S, Nunès JA, Olive D (September 2011).
1488:
1266:
1213:-mediated immune cell activation (for a more detailed discussion see
1130:
1074:
956:
708:
1536:
1285:). There are still no FDA approved inhibitors for PD-L2 as of 2019.
2129:
Wang ZL, Li GZ, Wang QW, Bao ZS, Wang Z, Zhang CB, Jiang T (2019).
1748:
4964:
4939:
4859:
4854:
4844:
4834:
4819:
4814:
4809:
4794:
4748:
4733:
4698:
4683:
4678:
4668:
4588:
4583:
4578:
4557:
4553:
4543:
4456:
4357:
4352:
4311:
4261:
4256:
4251:
4246:
4231:
4224:
4204:
4192:
4135:
4130:
4125:
4115:
4110:
4103:
4041:
4031:
4026:
4021:
4011:
3990:
3980:
3945:
3940:
3935:
3930:
3925:
3880:
3875:
3841:
3806:
3801:
3796:
3786:
3774:
3769:
3749:
3744:
3739:
3734:
3688:
3580:
3575:
3394:
3378:
3371:
3366:
3361:
3356:
3351:
3346:
3321:
3299:
3294:
3187:
3113:
3108:
3098:
2922:
2917:
2907:
2634:
Saunders PA, Hendrycks VR, Lidinsky WA, Woods ML (December 2005).
1427:
1254:
1041:
1026:
receptor ligand which plays a role in negative regulation of the
671:
667:
4959:
4954:
4944:
4934:
4929:
4924:
4879:
4869:
4829:
4758:
4728:
4723:
4718:
4713:
4708:
4703:
4658:
4628:
4533:
4501:
4496:
4476:
4466:
4461:
4446:
4441:
4342:
4337:
4306:
4286:
4281:
4271:
4266:
4145:
4098:
4058:
3713:
3708:
3703:
3698:
3683:
3674:
3669:
3664:
3649:
3607:
3602:
3592:
3587:
3570:
3565:
3560:
3555:
3550:
3545:
3540:
3535:
3530:
3466:
3439:
3434:
3429:
3404:
3399:
3336:
3331:
3326:
3316:
3311:
3264:
3259:
3254:
3244:
3239:
3222:
3217:
3212:
3202:
3197:
3182:
3177:
3172:
3162:
3157:
3152:
3135:
3130:
3125:
3076:
3044:
3039:
3034:
3017:
3012:
3007:
3002:
2897:
2892:
1011:
501:
61:
2942:
2842:
1153:
is widely expressed and not enriched in any particular tissue.
4471:
3083:
3071:
3066:
3061:
3051:
3024:
2992:
1315:
and other studies suggesting it predicts positive prognoses.
1311:
in cancer, with some studies suggesting it predicts negative
1205:
of 11.3 nM. Binding to PD-1 can activate pathways inhibiting
2055:"Search of: PDCD1LG2 - List Results - ClinicalTrials.gov"
1137:. Additionally, PD-L2 has moderate to high expression in
1458:"Entrez Gene: PDCD1LG2 programmed cell death 1 ligand 2"
317:
5000:
1997:"Regulation of T cell activation and tolerance by PDL2"
602:
negative regulation of activated T cell proliferation
482:
4777:
4571:
4320:
4004:
3727:
3387:
2985:
2885:
2413:
1288:The direct role of PD-L2 in cancer progression and
917:
896:
870:
849:
1352:
1350:
1348:
1331:
1329:
1327:
1189:induce moderate upregulation of PD-L2 expression.
622:negative regulation of interferon-gamma production
264:
163:
1166:granulocyte-macrophage colony stimulating factor
1113:. Others have shown PD-L2 expression in certain
1030:response. PD-L2 is one of two known ligands for
612:negative regulation of interleukin-10 production
16:Protein-coding gene in the species Homo sapiens
1473:"PD-1 as a potential target in cancer therapy"
1409:
1407:
1405:
1357:GRCm38: Ensembl release 89: ENSMUSG00000016498
5020:
2954:
2854:
1101:PD-L2 is primarily expressed on professional
8:
1168:(GMCSF) both upregulate PD-L2 expression in
2521:He XH, Liu Y, Xu LH, Zeng YY (April 2004).
1336:GRCh38: Ensembl release 89: ENSG00000197646
632:positive regulation of T cell proliferation
617:negative regulation of T cell proliferation
5027:
5013:
2961:
2947:
2939:
2861:
2847:
2839:
682:
517:
305:
204:
101:
2978:list of human clusters of differentiation
2831:at the U.S. National Library of Medicine
2737:
2702:
2651:
2616:
2581:
2538:
2457:
2393:
2358:
2305:
2256:
2246:
2205:
2195:
2154:
2105:
2095:
2030:
2020:
1966:
1912:
1704:
1694:
1645:
1635:
1594:
1496:
1227:experimental autoimmune encephalomyelitis
2757:The American Journal of Gastroenterology
1471:McDermott DF, Atkins MB (October 2013).
1299:Indirectly, PD-L2 may have utility as a
1323:
1269:. Due to their role in suppressing the
1014:. PDCD1LG2 has also been designated as
647:cellular response to lipopolysaccharide
642:cell surface receptor signaling pathway
1197:PD-L2 binds to its receptor PD-1 with
18:
2178:Yang H, Zhou X, Sun L, Mao Y (2019).
1990:
1988:
1986:
1936:
1934:
1932:
1890:
1888:
1886:
1861:
1859:
1730:
1728:
1726:
1724:
269:
230:
225:
168:
127:
122:
7:
4981:
4979:
2527:Acta Biochimica et Biophysica Sinica
2339:The Journal of Experimental Medicine
1575:The Journal of Experimental Medicine
1564:
1562:
1518:
1516:
1217:). PD-L2 plays an important role in
2556:Zhang Z, Henzel WJ (October 2004).
1067:immunoglobulin-like constant domain
1063:immunoglobulin-like variable domain
4999:. You can help Knowledge (XXG) by
1003:(also known as PD-L2, B7-DC) is a
914:
893:
867:
846:
822:
803:
777:
758:
732:
713:
487:
405:
343:
322:
14:
2498:10.1097/01.TP.0000108637.65091.4B
1261:expressions are important in the
1007:that in humans is encoded by the
4983:
2769:10.1111/j.1572-0241.2006.00948.x
1669:Tang S, Kim PS (December 2019).
1077:, namely SQDXXXELY or XXXYXXRT.
1001:Programmed cell death 1 ligand 2
581:external side of plasma membrane
491:
253:
246:
240:
217:
152:
145:
139:
114:
1867:"Tissue expression of PDCD1LG2"
1032:Programmed cell death protein 1
2683:European Journal of Immunology
2640:European Journal of Immunology
2446:European Journal of Immunology
556:integral component of membrane
502:More reference expression data
471:More reference expression data
1:
2806:10.1093/rheumatology/34.8.721
2618:10.1158/1078-0432.CCR-04-1469
2425:10.1016/S0006-291X(03)01257-9
2298:10.1080/2162402X.2016.1235107
2147:10.1080/2162402X.2018.1541535
2097:10.1158/1078-0432.CCR-18-3991
1914:10.1158/1078-0432.CCR-16-1761
1290:immune-tumor microenvironment
1139:triple-negative breast cancer
238:
137:
2235:Journal of Clinical Oncology
1842:10.1016/j.molimm.2011.09.014
1799:10.1016/j.molimm.2011.06.436
1296:-mediated immune responses.
5051:Clusters of differentiation
5046:Genes on human chromosome 9
2974:clusters of differentiation
2794:The Journal of Rheumatology
2395:10.4049/jimmunol.170.3.1257
359:stromal cell of endometrium
5072:
4978:
2878:immunoglobulin superfamily
1525:Nature Reviews. Immunology
1020:cluster of differentiation
1392:"Mouse PubMed Reference:"
1374:"Human PubMed Reference:"
1061:. It consists of both an
987:
982:
978:
971:
955:
936:
921:
900:
889:
874:
853:
842:
829:
825:
810:
806:
797:
784:
780:
765:
761:
752:
739:
735:
720:
716:
707:
692:
685:
681:
665:
520:
516:
499:
490:
481:
468:
417:
408:
355:
346:
316:
308:
304:
287:
274:
237:
216:
207:
203:
186:
173:
136:
113:
104:
100:
55:
52:
42:
35:
30:
26:
21:
2833:Medical Subject Headings
2605:Clinical Cancer Research
2084:Clinical Cancer Research
1947:International Immunology
1901:Clinical Cancer Research
1103:antigen presenting cells
949:Chr 19: 29.39 – 29.45 Mb
652:adaptive immune response
2829:PDCD1LG2+protein,+human
2739:10.1038/sj.gene.6364360
2197:10.3389/fonc.2019.00047
2022:10.1073/pnas.0601347103
1871:The Human Protein Atlas
1696:10.1073/pnas.1916916116
1637:10.1073/pnas.0804453105
391:upper lobe of left lung
5056:Membrane protein stubs
4995:–related article is a
1271:adaptive immune system
1145:and low expression in
1050:
441:lumbar spinal ganglion
437:mesenteric lymph nodes
2695:10.1002/eji.200535344
2653:10.1002/eji.200526347
2540:10.1093/abbs/36.4.284
2459:10.1002/eji.200324084
2382:Journal of Immunology
2351:10.1084/jem.193.7.839
2184:Frontiers in Oncology
1959:10.1093/intimm/dxq049
1587:10.1084/jem.193.7.839
1249:Clinical significance
1233:production in murine
1199:dissociation constant
1055:cell surface receptor
1047:X-ray crystallography
1045:
1022:273). PDCD1LG2 is an
942:Chr 9: 5.51 – 5.57 Mb
657:immune system process
232:Chromosome 19 (mouse)
2248:10.1200/JCO.18.02365
1830:Molecular Immunology
1787:Molecular Immunology
1147:renal cell carcinoma
607:T cell costimulation
561:extracellular region
387:smooth muscle tissue
130:Chromosome 9 (human)
94:PDCD1LG2 - orthologs
2574:10.1110/ps.04682504
2013:2006PNAS..10311695Z
1687:2019PNAS..11624500T
1681:(49): 24500–24506.
637:signal transduction
566:endomembrane system
429:submandibular gland
2726:Genes and Immunity
2059:clinicaltrials.gov
1051:
787:ENSMUSG00000016498
595:Biological process
549:Cellular component
535:molecular function
528:Molecular function
445:tibiofemoral joint
5008:
5007:
4973:
4972:
2936:
2935:
2241:(34): 3300–3309.
2090:(15): 4808–4819.
2007:(31): 11695–700.
1907:(12): 3158–3167.
1793:(15–16): 2214–9.
1737:Nature Immunology
1416:Nature Immunology
1119:cytotoxic T cells
1082:crystal structure
1071:sequence homology
1059:B7 protein family
1057:belonging to the
1024:immune checkpoint
998:
997:
994:
993:
967:
966:
932:
931:
911:
910:
885:
884:
864:
863:
838:
837:
819:
818:
793:
792:
774:
773:
748:
747:
729:
728:
677:
676:
512:
511:
508:
507:
477:
476:
464:
463:
402:
401:
300:
299:
199:
198:
5063:
5029:
5022:
5015:
4993:membrane protein
4987:
4980:
2963:
2956:
2949:
2940:
2863:
2856:
2849:
2840:
2817:
2788:
2751:
2741:
2716:
2706:
2673:
2655:
2630:
2620:
2595:
2585:
2552:
2542:
2517:
2479:
2461:
2436:
2407:
2397:
2372:
2362:
2320:
2319:
2309:
2292:(11): e1235107.
2277:
2271:
2270:
2260:
2250:
2226:
2220:
2219:
2209:
2199:
2175:
2169:
2168:
2158:
2126:
2120:
2119:
2109:
2099:
2075:
2069:
2068:
2066:
2065:
2051:
2045:
2044:
2034:
2024:
1992:
1981:
1980:
1970:
1938:
1927:
1926:
1916:
1892:
1881:
1880:
1878:
1877:
1863:
1854:
1853:
1825:
1819:
1818:
1784:
1775:
1769:
1768:
1732:
1719:
1718:
1708:
1698:
1666:
1660:
1659:
1649:
1639:
1615:
1609:
1608:
1598:
1566:
1557:
1556:
1520:
1511:
1510:
1500:
1489:10.1002/cam4.106
1468:
1462:
1461:
1454:
1448:
1447:
1411:
1400:
1399:
1388:
1382:
1381:
1370:
1364:
1354:
1343:
1333:
1294:cytotoxic T cell
1219:immune tolerance
1127:skeletal muscles
980:
979:
951:
944:
927:
915:
906:
894:
890:RefSeq (protein)
880:
868:
859:
847:
823:
804:
778:
759:
733:
714:
683:
518:
504:
495:
488:
473:
413:
411:Top expressed in
406:
351:
349:Top expressed in
344:
323:
306:
296:
283:
272:
257:
250:
244:
233:
221:
205:
195:
182:
171:
156:
149:
143:
132:
118:
102:
96:
47:
40:
19:
5071:
5070:
5066:
5065:
5064:
5062:
5061:
5060:
5036:
5035:
5034:
5033:
4976:
4974:
4969:
4773:
4567:
4316:
4000:
3723:
3383:
2981:
2967:
2937:
2932:
2881:
2867:
2825:
2820:
2791:
2754:
2719:
2676:
2633:
2598:
2568:(10): 2819–24.
2562:Protein Science
2555:
2520:
2486:Transplantation
2482:
2452:(10): 2773–82.
2439:
2410:
2375:
2332:
2328:
2326:Further reading
2323:
2279:
2278:
2274:
2228:
2227:
2223:
2177:
2176:
2172:
2141:(2): e1541535.
2128:
2127:
2123:
2077:
2076:
2072:
2063:
2061:
2053:
2052:
2048:
1994:
1993:
1984:
1940:
1939:
1930:
1894:
1893:
1884:
1875:
1873:
1865:
1864:
1857:
1827:
1826:
1822:
1782:
1777:
1776:
1772:
1734:
1733:
1722:
1668:
1667:
1663:
1630:(30): 10483–8.
1617:
1616:
1612:
1568:
1567:
1560:
1537:10.1038/nri1349
1522:
1521:
1514:
1477:Cancer Medicine
1470:
1469:
1465:
1456:
1455:
1451:
1413:
1412:
1403:
1390:
1389:
1385:
1372:
1371:
1367:
1355:
1346:
1334:
1325:
1321:
1263:immune response
1251:
1245:proliferation.
1235:dendritic cells
1204:
1195:
1159:
1107:dendritic cells
1099:
1094:
1040:
1028:adaptive immune
989:View/Edit Mouse
984:View/Edit Human
947:
940:
937:Location (UCSC)
923:
902:
876:
855:
768:ENSG00000197646
661:
627:immune response
590:
576:plasma membrane
544:
540:protein binding
500:
469:
460:
455:
453:skin of abdomen
451:
447:
443:
439:
435:
431:
427:
423:
409:
398:
393:
389:
385:
381:
377:
373:
369:
367:Achilles tendon
365:
361:
347:
291:
278:
270:
260:
259:
258:
251:
231:
208:Gene location (
190:
177:
169:
159:
158:
157:
150:
128:
105:Gene location (
56:
43:
36:
17:
12:
11:
5:
5069:
5067:
5059:
5058:
5053:
5048:
5038:
5037:
5032:
5031:
5024:
5017:
5009:
5006:
5005:
4988:
4971:
4970:
4968:
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4962:
4957:
4952:
4947:
4942:
4937:
4932:
4927:
4922:
4917:
4912:
4907:
4902:
4897:
4892:
4887:
4882:
4877:
4872:
4867:
4862:
4857:
4852:
4847:
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4837:
4832:
4827:
4822:
4817:
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4807:
4802:
4797:
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4779:
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4771:
4766:
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4756:
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4716:
4711:
4706:
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4666:
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4651:
4646:
4641:
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4606:
4601:
4596:
4591:
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4569:
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4560:
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4521:
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4511:
4506:
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4504:
4499:
4489:
4484:
4479:
4474:
4469:
4464:
4459:
4454:
4449:
4444:
4439:
4434:
4429:
4424:
4418:
4409:
4404:
4403:
4402:
4397:
4387:
4382:
4381:
4380:
4375:
4365:
4360:
4355:
4350:
4345:
4340:
4335:
4330:
4324:
4322:
4318:
4317:
4315:
4314:
4309:
4304:
4299:
4294:
4289:
4284:
4279:
4274:
4269:
4264:
4259:
4254:
4249:
4244:
4239:
4234:
4229:
4228:
4227:
4222:
4212:
4207:
4202:
4197:
4196:
4195:
4190:
4185:
4175:
4170:
4165:
4160:
4155:
4154:
4153:
4148:
4138:
4133:
4128:
4123:
4118:
4113:
4108:
4107:
4106:
4101:
4091:
4085:
4080:
4075:
4070:
4061:
4056:
4055:
4054:
4049:
4044:
4034:
4029:
4024:
4019:
4014:
4008:
4006:
4002:
4001:
3999:
3998:
3993:
3988:
3983:
3978:
3973:
3968:
3963:
3958:
3953:
3948:
3943:
3938:
3933:
3928:
3923:
3918:
3913:
3908:
3903:
3898:
3893:
3888:
3883:
3878:
3873:
3872:
3871:
3866:
3856:
3855:
3854:
3849:
3839:
3834:
3829:
3824:
3819:
3814:
3809:
3804:
3799:
3794:
3789:
3784:
3779:
3778:
3777:
3772:
3762:
3757:
3752:
3747:
3742:
3737:
3731:
3729:
3725:
3724:
3722:
3721:
3716:
3711:
3706:
3701:
3696:
3691:
3686:
3681:
3672:
3667:
3662:
3657:
3652:
3647:
3646:
3645:
3640:
3635:
3630:
3625:
3620:
3610:
3605:
3600:
3595:
3590:
3585:
3584:
3583:
3578:
3568:
3563:
3558:
3553:
3548:
3543:
3538:
3533:
3528:
3527:
3526:
3521:
3516:
3511:
3506:
3501:
3491:
3490:
3489:
3484:
3479:
3469:
3464:
3463:
3462:
3457:
3452:
3442:
3437:
3432:
3427:
3422:
3417:
3412:
3407:
3402:
3397:
3391:
3389:
3385:
3384:
3382:
3381:
3376:
3375:
3374:
3369:
3364:
3359:
3354:
3349:
3339:
3334:
3329:
3324:
3319:
3314:
3309:
3308:
3307:
3302:
3297:
3292:
3282:
3277:
3272:
3267:
3262:
3257:
3252:
3247:
3242:
3237:
3236:
3235:
3230:
3220:
3215:
3210:
3205:
3200:
3195:
3190:
3185:
3180:
3175:
3170:
3165:
3160:
3155:
3150:
3149:
3148:
3143:
3133:
3128:
3123:
3118:
3117:
3116:
3111:
3106:
3101:
3091:
3086:
3081:
3080:
3079:
3069:
3064:
3059:
3054:
3049:
3048:
3047:
3042:
3037:
3027:
3022:
3021:
3020:
3015:
3010:
3005:
3000:
2989:
2987:
2983:
2982:
2968:
2966:
2965:
2958:
2951:
2943:
2934:
2933:
2931:
2930:
2925:
2920:
2915:
2910:
2905:
2900:
2895:
2889:
2887:
2883:
2882:
2868:
2866:
2865:
2858:
2851:
2843:
2837:
2836:
2824:
2823:External links
2821:
2819:
2818:
2789:
2752:
2717:
2689:(5): 1104–13.
2674:
2646:(12): 3561–9.
2631:
2611:(8): 2947–53.
2596:
2553:
2518:
2480:
2437:
2408:
2388:(3): 1257–66.
2373:
2329:
2327:
2324:
2322:
2321:
2286:Oncoimmunology
2272:
2221:
2170:
2135:Oncoimmunology
2121:
2070:
2046:
1982:
1928:
1882:
1855:
1820:
1770:
1749:10.1038/ni1443
1720:
1661:
1610:
1558:
1512:
1463:
1449:
1401:
1383:
1365:
1344:
1322:
1320:
1317:
1250:
1247:
1215:PD-1 signaling
1202:
1194:
1191:
1158:
1155:
1143:gastric cancer
1098:
1095:
1093:
1090:
1039:
1036:
996:
995:
992:
991:
986:
976:
975:
969:
968:
965:
964:
962:
960:
953:
952:
945:
938:
934:
933:
930:
929:
919:
918:
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909:
908:
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891:
887:
886:
883:
882:
872:
871:
865:
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861:
851:
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844:
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836:
835:
827:
826:
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790:
782:
781:
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771:
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745:
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736:
730:
727:
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718:
717:
711:
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531:
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376:
372:
368:
364:
360:
356:
353:
352:
340:
339:
331:
320:
314:
313:
310:RNA expression
302:
301:
298:
297:
289:
285:
284:
276:
273:
268:
262:
261:
252:
245:
239:
235:
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111:
110:
98:
97:
54:
50:
49:
41:
33:
32:
28:
27:
24:
23:
15:
13:
10:
9:
6:
4:
3:
2:
5068:
5057:
5054:
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5049:
5047:
5044:
5043:
5041:
5030:
5025:
5023:
5018:
5016:
5011:
5010:
5004:
5002:
4998:
4994:
4989:
4986:
4982:
4977:
4966:
4963:
4961:
4958:
4956:
4953:
4951:
4948:
4946:
4943:
4941:
4938:
4936:
4933:
4931:
4928:
4926:
4923:
4921:
4918:
4916:
4913:
4911:
4908:
4906:
4903:
4901:
4898:
4896:
4893:
4891:
4888:
4886:
4883:
4881:
4878:
4876:
4873:
4871:
4868:
4866:
4863:
4861:
4858:
4856:
4853:
4851:
4848:
4846:
4843:
4841:
4838:
4836:
4833:
4831:
4828:
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4823:
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4806:
4803:
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4776:
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4725:
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4717:
4715:
4712:
4710:
4707:
4705:
4702:
4700:
4697:
4695:
4692:
4690:
4687:
4685:
4682:
4680:
4677:
4675:
4672:
4670:
4667:
4665:
4662:
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4657:
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4607:
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4602:
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4597:
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4280:
4278:
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4270:
4268:
4265:
4263:
4260:
4258:
4255:
4253:
4250:
4248:
4245:
4243:
4240:
4238:
4235:
4233:
4230:
4226:
4223:
4221:
4218:
4217:
4216:
4213:
4211:
4208:
4206:
4203:
4201:
4198:
4194:
4191:
4189:
4186:
4184:
4181:
4180:
4179:
4176:
4174:
4171:
4169:
4166:
4164:
4161:
4159:
4156:
4152:
4149:
4147:
4144:
4143:
4142:
4139:
4137:
4134:
4132:
4129:
4127:
4124:
4122:
4119:
4117:
4114:
4112:
4109:
4105:
4102:
4100:
4097:
4096:
4095:
4092:
4089:
4086:
4084:
4081:
4079:
4076:
4074:
4071:
4069:
4065:
4062:
4060:
4057:
4053:
4050:
4048:
4045:
4043:
4040:
4039:
4038:
4035:
4033:
4030:
4028:
4025:
4023:
4020:
4018:
4015:
4013:
4010:
4009:
4007:
4003:
3997:
3994:
3992:
3989:
3987:
3984:
3982:
3979:
3977:
3974:
3972:
3969:
3967:
3964:
3962:
3959:
3957:
3954:
3952:
3949:
3947:
3944:
3942:
3939:
3937:
3934:
3932:
3929:
3927:
3924:
3922:
3919:
3917:
3914:
3912:
3909:
3907:
3904:
3902:
3899:
3897:
3894:
3892:
3889:
3887:
3884:
3882:
3879:
3877:
3874:
3870:
3867:
3865:
3862:
3861:
3860:
3857:
3853:
3850:
3848:
3845:
3844:
3843:
3840:
3838:
3835:
3833:
3830:
3828:
3825:
3823:
3820:
3818:
3815:
3813:
3810:
3808:
3805:
3803:
3800:
3798:
3795:
3793:
3790:
3788:
3785:
3783:
3780:
3776:
3773:
3771:
3768:
3767:
3766:
3763:
3761:
3758:
3756:
3753:
3751:
3748:
3746:
3743:
3741:
3738:
3736:
3733:
3732:
3730:
3726:
3720:
3717:
3715:
3712:
3710:
3707:
3705:
3702:
3700:
3697:
3695:
3692:
3690:
3687:
3685:
3682:
3680:
3676:
3673:
3671:
3668:
3666:
3663:
3661:
3658:
3656:
3653:
3651:
3648:
3644:
3641:
3639:
3636:
3634:
3631:
3629:
3626:
3624:
3621:
3619:
3616:
3615:
3614:
3611:
3609:
3606:
3604:
3601:
3599:
3596:
3594:
3591:
3589:
3586:
3582:
3579:
3577:
3574:
3573:
3572:
3569:
3567:
3564:
3562:
3559:
3557:
3554:
3552:
3549:
3547:
3544:
3542:
3539:
3537:
3534:
3532:
3529:
3525:
3522:
3520:
3517:
3515:
3512:
3510:
3507:
3505:
3502:
3500:
3497:
3496:
3495:
3492:
3488:
3485:
3483:
3480:
3478:
3475:
3474:
3473:
3470:
3468:
3465:
3461:
3458:
3456:
3453:
3451:
3448:
3447:
3446:
3443:
3441:
3438:
3436:
3433:
3431:
3428:
3426:
3423:
3421:
3418:
3416:
3413:
3411:
3408:
3406:
3403:
3401:
3398:
3396:
3393:
3392:
3390:
3386:
3380:
3377:
3373:
3370:
3368:
3365:
3363:
3360:
3358:
3355:
3353:
3350:
3348:
3345:
3344:
3343:
3340:
3338:
3335:
3333:
3330:
3328:
3325:
3323:
3320:
3318:
3315:
3313:
3310:
3306:
3303:
3301:
3298:
3296:
3293:
3291:
3288:
3287:
3286:
3283:
3281:
3278:
3276:
3273:
3271:
3268:
3266:
3263:
3261:
3258:
3256:
3253:
3251:
3248:
3246:
3243:
3241:
3238:
3234:
3231:
3229:
3226:
3225:
3224:
3221:
3219:
3216:
3214:
3211:
3209:
3206:
3204:
3201:
3199:
3196:
3194:
3191:
3189:
3186:
3184:
3181:
3179:
3176:
3174:
3171:
3169:
3166:
3164:
3161:
3159:
3156:
3154:
3151:
3147:
3144:
3142:
3139:
3138:
3137:
3134:
3132:
3129:
3127:
3124:
3122:
3119:
3115:
3112:
3110:
3107:
3105:
3102:
3100:
3097:
3096:
3095:
3092:
3090:
3087:
3085:
3082:
3078:
3075:
3074:
3073:
3070:
3068:
3065:
3063:
3060:
3058:
3055:
3053:
3050:
3046:
3043:
3041:
3038:
3036:
3033:
3032:
3031:
3028:
3026:
3023:
3019:
3016:
3014:
3011:
3009:
3006:
3004:
3001:
2999:
2996:
2995:
2994:
2991:
2990:
2988:
2984:
2979:
2975:
2971:
2964:
2959:
2957:
2952:
2950:
2945:
2944:
2941:
2929:
2926:
2924:
2921:
2919:
2916:
2914:
2911:
2909:
2906:
2904:
2901:
2899:
2896:
2894:
2891:
2890:
2888:
2884:
2879:
2875:
2871:
2864:
2859:
2857:
2852:
2850:
2845:
2844:
2841:
2834:
2830:
2827:
2826:
2822:
2815:
2811:
2807:
2803:
2799:
2795:
2790:
2786:
2782:
2778:
2774:
2770:
2766:
2763:(2): 302–12.
2762:
2758:
2753:
2749:
2745:
2740:
2735:
2731:
2727:
2723:
2718:
2714:
2710:
2705:
2700:
2696:
2692:
2688:
2684:
2680:
2675:
2671:
2667:
2663:
2659:
2654:
2649:
2645:
2641:
2637:
2632:
2628:
2624:
2619:
2614:
2610:
2606:
2602:
2597:
2593:
2589:
2584:
2579:
2575:
2571:
2567:
2563:
2559:
2554:
2550:
2546:
2541:
2536:
2532:
2528:
2524:
2519:
2515:
2511:
2507:
2503:
2499:
2495:
2491:
2487:
2481:
2477:
2473:
2469:
2465:
2460:
2455:
2451:
2447:
2443:
2438:
2434:
2430:
2426:
2422:
2418:
2414:
2409:
2405:
2401:
2396:
2391:
2387:
2383:
2379:
2374:
2370:
2366:
2361:
2356:
2352:
2348:
2345:(7): 839–46.
2344:
2340:
2336:
2331:
2330:
2325:
2317:
2313:
2308:
2303:
2299:
2295:
2291:
2287:
2283:
2276:
2273:
2268:
2264:
2259:
2254:
2249:
2244:
2240:
2236:
2232:
2225:
2222:
2217:
2213:
2208:
2203:
2198:
2193:
2189:
2185:
2181:
2174:
2171:
2166:
2162:
2157:
2152:
2148:
2144:
2140:
2136:
2132:
2125:
2122:
2117:
2113:
2108:
2103:
2098:
2093:
2089:
2085:
2081:
2074:
2071:
2060:
2056:
2050:
2047:
2042:
2038:
2033:
2028:
2023:
2018:
2014:
2010:
2006:
2002:
1998:
1991:
1989:
1987:
1983:
1978:
1974:
1969:
1964:
1960:
1956:
1953:(8): 651–60.
1952:
1948:
1944:
1937:
1935:
1933:
1929:
1924:
1920:
1915:
1910:
1906:
1902:
1898:
1891:
1889:
1887:
1883:
1872:
1868:
1862:
1860:
1856:
1851:
1847:
1843:
1839:
1835:
1831:
1824:
1821:
1816:
1812:
1808:
1804:
1800:
1796:
1792:
1788:
1781:
1774:
1771:
1766:
1762:
1758:
1754:
1750:
1746:
1743:(3): 239–45.
1742:
1738:
1731:
1729:
1727:
1725:
1721:
1716:
1712:
1707:
1702:
1697:
1692:
1688:
1684:
1680:
1676:
1672:
1665:
1662:
1657:
1653:
1648:
1643:
1638:
1633:
1629:
1625:
1621:
1614:
1611:
1606:
1602:
1597:
1592:
1588:
1584:
1581:(7): 839–46.
1580:
1576:
1572:
1565:
1563:
1559:
1554:
1550:
1546:
1542:
1538:
1534:
1531:(5): 336–47.
1530:
1526:
1519:
1517:
1513:
1508:
1504:
1499:
1494:
1490:
1486:
1483:(5): 662–73.
1482:
1478:
1474:
1467:
1464:
1459:
1453:
1450:
1445:
1441:
1437:
1433:
1429:
1428:10.1038/85330
1425:
1421:
1417:
1410:
1408:
1406:
1402:
1397:
1393:
1387:
1384:
1379:
1375:
1369:
1366:
1362:
1358:
1353:
1351:
1349:
1345:
1341:
1337:
1332:
1330:
1328:
1324:
1318:
1316:
1314:
1310:
1306:
1305:pembrolizumab
1302:
1297:
1295:
1291:
1286:
1284:
1280:
1276:
1275:pembrolizumab
1272:
1268:
1264:
1260:
1256:
1248:
1246:
1244:
1243:T helper cell
1240:
1236:
1232:
1228:
1224:
1220:
1216:
1212:
1208:
1200:
1192:
1190:
1188:
1184:
1180:
1176:
1175:
1171:
1167:
1163:
1162:Interleukin-4
1156:
1154:
1152:
1148:
1144:
1140:
1136:
1132:
1128:
1124:
1120:
1116:
1115:T helper cell
1112:
1108:
1104:
1096:
1091:
1089:
1087:
1083:
1078:
1076:
1072:
1068:
1064:
1060:
1056:
1048:
1044:
1037:
1035:
1033:
1029:
1025:
1021:
1017:
1013:
1010:
1006:
1002:
990:
985:
981:
977:
974:
970:
963:
961:
958:
954:
950:
946:
943:
939:
935:
928:
926:
920:
916:
913:
907:
905:
899:
895:
892:
888:
881:
879:
873:
869:
866:
860:
858:
852:
848:
845:
843:RefSeq (mRNA)
841:
834:
833:
828:
824:
821:
815:
814:
809:
805:
802:
800:
796:
789:
788:
783:
779:
776:
770:
769:
764:
760:
757:
755:
751:
744:
743:
738:
734:
731:
725:
724:
719:
715:
712:
710:
706:
703:
700:
698:
695:
691:
688:
684:
680:
673:
669:
664:
658:
655:
653:
650:
648:
645:
643:
640:
638:
635:
633:
630:
628:
625:
623:
620:
618:
615:
613:
610:
608:
605:
603:
600:
599:
597:
594:
593:
587:
584:
582:
579:
577:
574:
572:
569:
567:
564:
562:
559:
557:
554:
553:
551:
548:
547:
541:
538:
536:
533:
532:
530:
527:
526:
523:
522:Gene ontology
519:
515:
503:
498:
494:
489:
486:
484:
480:
472:
467:
456:
452:
448:
444:
440:
436:
432:
428:
424:
420:
419:
416:
412:
407:
404:
394:
390:
386:
382:
378:
374:
370:
366:
362:
358:
357:
354:
350:
345:
342:
341:
338:
336:
332:
330:
329:
325:
324:
321:
319:
315:
311:
307:
303:
295:
290:
286:
282:
277:
271:19|19 C1
267:
263:
256:
249:
243:
236:
228:
224:
220:
215:
211:
206:
202:
194:
189:
185:
181:
176:
166:
162:
155:
148:
142:
135:
131:
125:
121:
117:
112:
108:
103:
99:
95:
91:
87:
83:
79:
75:
71:
67:
63:
59:
51:
46:
39:
34:
29:
25:
20:
5001:expanding it
4990:
4975:
4663:
4491:
4411:
4389:
4367:
4214:
4177:
4140:
4093:
4063:
4036:
3858:
3764:
3612:
3341:
3093:
2902:
2800:(4): 721–5.
2797:
2793:
2760:
2756:
2732:(1): 69–74.
2729:
2725:
2686:
2682:
2643:
2639:
2608:
2604:
2565:
2561:
2533:(4): 284–9.
2530:
2526:
2489:
2485:
2449:
2445:
2419:(3): 672–7.
2416:
2412:
2385:
2381:
2342:
2338:
2289:
2285:
2275:
2238:
2234:
2224:
2187:
2183:
2173:
2138:
2134:
2124:
2107:2324/4475014
2087:
2083:
2073:
2062:. Retrieved
2058:
2049:
2004:
2000:
1950:
1946:
1904:
1900:
1874:. Retrieved
1870:
1836:(1–2): 1–3.
1833:
1829:
1823:
1790:
1786:
1773:
1740:
1736:
1678:
1674:
1664:
1627:
1623:
1613:
1578:
1574:
1528:
1524:
1480:
1476:
1466:
1452:
1422:(3): 261–8.
1419:
1415:
1395:
1386:
1377:
1368:
1298:
1287:
1283:atezolizumab
1252:
1223:autoimmunity
1196:
1172:
1160:
1117:subsets and
1100:
1079:
1052:
1015:
1008:
1000:
999:
922:
901:
875:
854:
830:
811:
785:
766:
740:
721:
701:
696:
586:cell surface
333:
326:
53:External IDs
2492:(1): 6–12.
1265:to certain
1164:(IL-4) and
1111:macrophages
1053:PD-L2 is a
383:gallbladder
292:29,448,561
279:29,388,319
31:Identifiers
5040:Categories
2976:(see also
2886:B7 ligands
2876:(see also
2064:2020-03-04
1876:2020-03-05
1363:, May 2017
1342:, May 2017
1319:References
1157:Regulation
1109:(DCs) and
1105:including
1092:Expression
1075:CD28/CTLA4
395:right lung
375:lymph node
337:(ortholog)
191:5,571,282
178:5,510,531
74:HomoloGene
2874:B7 family
1313:prognoses
1301:biomarker
1279:nivolumab
1125:tissues,
1038:Structure
925:NP_067371
904:NP_079515
878:NM_021396
857:NM_025239
687:Orthologs
82:GeneCards
2970:Proteins
2870:Proteins
2814:17343323
2777:17311651
2748:17136123
2713:16598819
2670:43876326
2662:16278812
2627:15837746
2592:15340161
2549:15253154
2514:25360886
2506:14724428
2476:34992725
2468:14515261
2433:12893276
2404:12538684
2369:11283156
2316:27999753
2267:31570492
2216:30891423
2165:30713802
2116:31076547
2041:16864790
1977:20587542
1923:28619999
1850:22000002
1815:33134166
1807:21752471
1757:17304234
1715:31727844
1656:18641123
1605:11283156
1553:33548210
1545:15122199
1507:24403232
1444:27659586
1436:11224527
1359:–
1338:–
1193:Function
1174:in vitro
1149:. PD-L2
1135:pancreas
1123:GI tract
1034:(PD-1).
1009:PDCD1LG2
973:Wikidata
666:Sources:
571:membrane
421:gastrula
371:appendix
363:testicle
86:PDCD1LG2
45:PDCD1LG2
22:PDCD1LG2
4778:301–350
4572:251–300
4524:CD240CE
4321:201–250
4005:151–200
3728:101–150
2785:8083797
2704:2975063
2583:2286551
2360:2193370
2307:5139635
2258:6784528
2207:6413700
2156:6343813
2032:1544232
2009:Bibcode
1968:3168865
1765:8749576
1706:6900541
1683:Bibcode
1647:2492495
1596:2193370
1498:3892798
1361:Ensembl
1340:Ensembl
1309:outcome
1267:cancers
1253:PD-L2,
1241:led to
1131:tonsils
1097:Profile
1065:and an
1005:protein
799:UniProt
754:Ensembl
693:Species
672:QuickGO
312:pattern
70:1930125
38:Aliases
4785:CD300A
4744:CDw293
4529:CD240D
4390:CD213a
4368:CDw210
4333:CD202b
4307:CDw199
4302:CDw198
3956:CD140b
3388:51–100
2835:(MeSH)
2812:
2783:
2775:
2746:
2711:
2701:
2668:
2660:
2625:
2590:
2580:
2547:
2512:
2504:
2474:
2466:
2431:
2402:
2367:
2357:
2314:
2304:
2265:
2255:
2214:
2204:
2190:: 47.
2163:
2153:
2114:
2039:
2029:
1975:
1965:
1921:
1848:
1813:
1805:
1763:
1755:
1713:
1703:
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