315:
much more common than expected. People with mtDNA diseases often harbour a mixture of normal and abnormal mtDNA (heteroplasmy). His group showed that most healthy people also carry heteroplasmic mtDNA mutations, but at very low levels. They showed that a dramatic reduction in mtDNA levels within female germ cells during embryonic development leads to major shifts in heteroplasmy levels over one generation (the mitochondrial genetic bottleneck). The bottleneck explains how low level heteroplasmy in carriers can lead to mitochondrial diseases within one generation, and the different severity of mtDNA disease seen in siblings within the same family. Carrying out the first large-scale study in the UK 100,000 genomes project, he showed that the nuclear genetic background also influences the inheritance pattern of mtDNA mutations. He also showed that genetic variation of mtDNA influences the risk of developing common diseases and many human physiological traits, including kidney and liver function.
25:
314:
in human disease. He has identified the genetic basis of several new diseases caused by genetic mutations affecting the genetic code within mitochondria (mtDNA) and the nuclear genome which code for mitochondrial proteins. In the first genetic epidemiology study he showed that mtDNA diseases were
271:, where he graduated with a Bachelor of Medical Science degree in 1989 with first class honours; and Bachelor of Medicine, Bachelor of Surgery with honours in 1992. He went on to complete his PhD in mitochondrial genetics in 2000 whilst training in clinical neurology and neurogenetics.
318:
He has been supported by
Wellcome Trust research fellowships since 1995, most recently as a Wellcome Principal Research Fellow. Additional research support has come from the Medical Research Council / UK Research and Innovation, and the National Institute for Health Research.
344:
He has advised to two UK Government Chief
Medical Advisors, and ministers and Secretaries of State within the Department of Health and Social Care and the Department of Business Energy and Industrial Strategy. In 2020 he was appointed National Core Study Lead for
287:
2002 when he was appointed
Honorary Consultant Neurologist at Newcastle upon Tyne Hospitals NHS Foundation Trust. He specializes in inherited disorders of the nervous system (neurogenetics) and established the north of England regional
331:(NIHR) Newcastle Biomedical Research Centre from 2008 to 2015, leading a doubling of funding. Since 2012 he has been co-chair of the NIHR Rare Diseases Translational Research Collaboration, then the NIHR BioResource with John Bradley.
1653:
1010:
730:
Floros, Vasileios I.; Pyle, Angela; Dietmann, Sabine; Wei, Wei; Tang, Walfred C. W.; Irie, Naoko; Payne, Brendan; Capalbo, Antonio; Noli, Laila; Coxhead, Jonathan; Hudson, Gavin (15 January 2018).
675:
Cree, Lynsey M; Samuels, David C; de Sousa Lopes, Susana Chuva; Rajasimha, Harsha Karur; Wonnapinij, Passorn; Mann, Jeffrey R; Dahl, Hans-Henrik M; Chinnery, Patrick F (27 January 2008).
341:
In 2018 he became
Clinical Director of the Medical Research Council within UK Research and Innovation, where is he was responsible for clinical translational research programmes.
1163:
1658:
618:
Payne, B. A. I.; Wilson, I. J.; Yu-Wai-Man, P.; Coxhead, J.; Deehan, D.; Horvath, R.; Taylor, R. W.; Samuels, D. C.; Santibanez-Koref, M.; Chinnery, P. F. (16 October 2012).
842:
Yonova-Doing, Ekaterina; Calabrese, Claudia; Gomez-Duran, Aurora; Schon, Katherine; Wei, Wei; Karthikeyan, Savita; Chinnery, Patrick F.; Howson, Joanna M. M. (17 May 2021).
1643:
459:
256:
512:
370:
338:
at
Newcastle University. In 2015 he moved to the University of Cambridge as Professor of Neurology and Head of the Department of Clinical Neurosciences.
563:
Chinnery, P. F.; Johnson, M. A.; Wardell, T. M.; Singh-Kler, R.; Hayes, C.; Brown, D. T.; Taylor, R. W.; Bindoff, L. A.; Turnbull, D. M. (August 2000).
53:
33:
357:
to established and chair the UK COVID-19 Therapeutics
Advisory Panel (UK-CTAP) which recommended drugs into the UK national clinical trial platforms.
252:
1504:
1648:
328:
1663:
304:
1673:
959:
366:
1668:
1146:
382:
126:
365:
Chinnery was awarded several prizes as a training neurologist and researcher, twice being awarded the
Charles Symonds Prize by the
1570:
107:
241:
79:
580:
1638:
1423:
1260:
378:
57:
49:
1280:
1275:
498:
86:
1305:
1219:
1155:
386:
374:
280:
148:
1035:
38:
907:
93:
42:
1180:
985:
300:
1395:
381:
since 2007. In 2010 he became a NIHR Senior
Investigator (now emeritus), and is a corresponding member of the
677:"A reduction of mitochondrial DNA molecules during embryogenesis explains the rapid segregation of genotypes"
75:
1139:
245:
732:"Segregation of mitochondrial DNA heteroplasmy through a developmental genetic bottleneck in human embryos"
1683:
1540:
1469:
1456:
1428:
1364:
1265:
1201:
296:
295:
In 2015 he moved to the
University of Cambridge as Professor of Neurology and Head of the Department of
279:
Chinnery trained as a physician and neurologist in the north east of
England, becoming a member of the
1678:
1499:
800:
385:. In 2022 he was awarded the Galen Medal by the Worshipful Society of Apothecaries. He was elected a
268:
183:
179:
1333:
1214:
1270:
889:
824:
712:
600:
248:, where he is also professor of neurology and head of the department of clinical neurosciences.
64:
1124:
212:
1550:
1132:
881:
863:
816:
769:
751:
704:
696:
657:
639:
592:
584:
453:
100:
1612:
1560:
1530:
1320:
1290:
1036:"The Foulkes Foundation Academy of Medical Sciences Medal | The Academy of Medical Sciences"
871:
855:
808:
759:
743:
688:
647:
631:
576:
565:<188::aid-ana8>3.0.co;2-p "The epidemiology of pathogenic mitochondrial DNA mutations"
350:
335:
1599:
1535:
1315:
1196:
1103:
373:, who awarded him the Foulkes Foundation Medal in 2011. He has been a Fellow of the
1346:
804:
1545:
1520:
1483:
1359:
1354:
1300:
1295:
876:
764:
652:
538:
406:
237:
1632:
1617:
1555:
1461:
1400:
1382:
1369:
1338:
1245:
1185:
1159:
893:
828:
716:
311:
289:
788:
604:
1607:
1584:
1565:
1446:
1441:
1390:
1377:
1255:
1224:
812:
564:
354:
844:"An atlas of mitochondrial DNA genotype–phenotype associations in the UK Biobank"
1589:
1410:
1325:
1229:
843:
431:
859:
731:
1594:
1436:
1415:
1405:
1310:
1250:
1206:
747:
435:"Professor Patrick F. Chinnery, FMedSci — Cambridge Centre for Parkinson-Plus"
867:
820:
755:
700:
643:
588:
434:
284:
201:
Association of British Neurologists, Charles Symonds Prize, 1997 & 2002
885:
773:
708:
661:
596:
1451:
1285:
635:
346:
299:
within the School of Clinical Medicine. He practices as a neurologist at
934:
676:
619:
353:. In 2020 he was asked by UK Government Chief Medical Advisor Professor
1011:"Guidance: making a proposal for COVID-19 therapeutics clinical trials"
692:
307:
College in 2017 where he is Director of Studies in Clinical Medicine.
1525:
259:
BioResource for Translational Research in Chronic and Rare Diseases.
236:, FRCP, FRCPath, FMedSci, is a neurologist, clinician scientist, and
581:
10.1002/1531-8249(200008)48:2<188::aid-ana8>3.0.co;2-p
1104:"Outstanding scientists elected as Fellows of the Royal Society"
1085:
369:(1997, 2002). In 2009 he was the youngest elected member of the
1128:
1060:
349:
therapeutics by the UK Government Chief Scientific Advisor Sir
171:
St Michaels College, Leeds, St Marys RC Comprehensive, Guiseley
63:
from the article and its talk page, especially if potentially
18:
960:"Chief Medical Officer annual report 2016: generation genome"
499:"Professor Patrick Chinnery appointed as MRC Executive Chair"
283:
in 1995, and completing his specialist clinical training in
1654:
Fellows of the Academy of Medical Sciences (United Kingdom)
473:
334:
In 2010 he was appointed Director of the Institute of
203:
Worshipful Society of Apothecaries, Galen Medal, 2022
1513:
1492:
1170:
620:"Universal heteroplasmy of human mitochondrial DNA"
539:"Patrick Chinnery | MRC Mitochondrial Biology Unit"
407:"Patrick Chinnery | MRC Mitochondrial Biology Unit"
242:
Medical Research Council Mitochondrial Biology Unit
207:
189:
175:
167:
155:
143:
310:His research focuses on understanding the role of
198:Fellow of the Academy of Medical Sciences, 2009,
251:In 2023 he was appointed executive chair of the
513:"MRC appoints neurologist as clinical director"
257:National Institute for Health and Care Research
1140:
789:"Heteroplasmy incidence in mitochondrial DNA"
8:
908:"BioResource results among ten key advances"
458:: CS1 maint: numeric names: authors list (
1659:Fellows of the Royal College of Physicians
1147:
1133:
1125:
140:
56:about living persons that is unsourced or
1644:Professors of the University of Cambridge
875:
763:
651:
253:Medical Research Council (United Kingdom)
127:Learn how and when to remove this message
935:"Patrick Chinnery (0000-0002-7065-6617)"
398:
240:Principal Research Fellow based in the
451:
329:National Institute for Health Research
986:"The National Core Studies programme"
7:
267:Chinnery attended Medical School at
367:Association of British Neurologists
234:Professor Patrick Francis Chinnery
14:
383:American Neurological Association
377:since 2006, and a Fellow of the
195:NIHR Senior Investigator, 2010,
193:Foulkes Foundation Medal, 2011,
23:
292:service between 2002 and 2015.
1649:Alumni of Newcastle University
813:10.1126/science.364.6442.746-k
787:Zahn, Laura M. (23 May 2019).
1:
379:Royal College of Pathologists
327:Chinnery was Director of the
1664:Fellows of the Royal Society
34:biography of a living person
387:Fellow of the Royal Society
375:Royal College of Physicians
371:Academy of Medical Sciences
281:Royal College of Physicians
275:Medical career and research
61:must be removed immediately
1700:
1674:Medical doctors from Leeds
860:10.1038/s41588-021-00868-1
517:Research Professional News
1669:NIHR Senior Investigators
748:10.1038/s41556-017-0017-8
624:Human Molecular Genetics
303:. He became a Fellow of
263:Early life and education
255:. He is co-chair of the
246:University of Cambridge
1541:Emmanuelle Charpentier
1470:Mihaela van der Schaar
1061:"Senior Investigators"
912:bioresource.nihr.ac.uk
301:Addenbrooke's Hospital
297:Clinical Neurosciences
48:Please help by adding
1429:Oscar Randal-Williams
1202:Sarah-Jayne Blakemore
543:www.mrc-mbu.cam.ac.uk
411:www.mrc-mbu.cam.ac.uk
1639:British neurologists
1500:Kwame Anthony Appiah
799:(6442): 746.11–748.
269:Newcastle University
184:Cambridge University
180:Newcastle University
54:Contentious material
1604:Paul Schulze-Lefert
1474:Bart Vanhaesebroeck
1334:Heidi Johansen Berg
1215:Emmanuel Breuillard
805:2019Sci...364..746Z
736:Nature Cell Biology
569:Annals of Neurology
145:Patrick F. Chinnery
16:British neurologist
1457:Lorraine Symington
1365:Douglas MacFarlane
1271:Rebecca Fitzgerald
914:. 23 December 2020
693:10.1038/ng.2007.63
636:10.1093/hmg/dds435
519:. 27 February 2019
305:Gonville and Caius
76:"Patrick Chinnery"
1626:
1625:
1551:Ingrid Daubechies
1276:Andrew Fitzgibbon
501:. 22 August 2023.
433:(23 March 2018).
361:Awards and honors
231:
230:
137:
136:
129:
111:
37:needs additional
1691:
1613:Mark H. Thiemens
1561:Thomas Henzinger
1374:George Malliaras
1321:Saskia Hogenhout
1291:Nigel Goldenfeld
1238:Patrick Chinnery
1186:Frances Balkwill
1149:
1142:
1135:
1126:
1119:
1118:
1116:
1114:
1100:
1094:
1093:
1082:
1076:
1075:
1073:
1071:
1057:
1051:
1050:
1048:
1046:
1032:
1026:
1025:
1023:
1021:
1007:
1001:
1000:
998:
996:
982:
976:
975:
973:
971:
956:
950:
949:
947:
945:
930:
924:
923:
921:
919:
904:
898:
897:
879:
839:
833:
832:
784:
778:
777:
767:
727:
721:
720:
672:
666:
665:
655:
615:
609:
608:
560:
554:
553:
551:
549:
535:
529:
528:
526:
524:
509:
503:
502:
495:
489:
488:
486:
484:
470:
464:
463:
457:
449:
447:
445:
428:
422:
421:
419:
417:
403:
351:Patrick Vallance
336:Genetic Medicine
227:
224:
223:/research-groups
222:
220:
218:
216:
214:
159:11 February 1968
141:
132:
125:
121:
118:
112:
110:
69:
50:reliable sources
27:
26:
19:
1699:
1698:
1694:
1693:
1692:
1690:
1689:
1688:
1629:
1628:
1627:
1622:
1578:Anthony Movshon
1571:Susana Magallón
1536:Emily A. Carter
1509:
1488:
1387:Stephen McGrath
1330:Richard Jardine
1306:Richard Hartley
1281:Michael Garrett
1230:Kenneth Carslaw
1220:Philip Campbell
1197:Donna Blackmond
1166:
1153:
1123:
1122:
1112:
1110:
1102:
1101:
1097:
1090:si.gmg-is.co.uk
1086:"Faculty Focus"
1084:
1083:
1079:
1069:
1067:
1065:si.gmg-is.co.uk
1059:
1058:
1054:
1044:
1042:
1034:
1033:
1029:
1019:
1017:
1009:
1008:
1004:
994:
992:
984:
983:
979:
969:
967:
958:
957:
953:
943:
941:
932:
931:
927:
917:
915:
906:
905:
901:
848:Nature Genetics
841:
840:
836:
786:
785:
781:
729:
728:
724:
681:Nature Genetics
674:
673:
669:
617:
616:
612:
562:
561:
557:
547:
545:
537:
536:
532:
522:
520:
511:
510:
506:
497:
496:
492:
482:
480:
472:
471:
467:
450:
443:
441:
430:
429:
425:
415:
413:
405:
404:
400:
395:
363:
325:
277:
265:
225:/chinnery-group
211:
176:Alma mater
163:
160:
151:
146:
133:
122:
116:
113:
70:
68:
47:
28:
24:
17:
12:
11:
5:
1697:
1695:
1687:
1686:
1681:
1676:
1671:
1666:
1661:
1656:
1651:
1646:
1641:
1631:
1630:
1624:
1623:
1621:
1620:
1615:
1610:
1605:
1602:
1597:
1592:
1587:
1582:
1579:
1576:
1573:
1568:
1563:
1558:
1553:
1548:
1546:Patrick Cramer
1543:
1538:
1533:
1528:
1523:
1521:Yakir Aharonov
1517:
1515:
1511:
1510:
1508:
1507:
1505:Anthony Hughes
1502:
1496:
1494:
1490:
1489:
1487:
1486:
1484:Xiaodong Zhang
1481:
1480:William Wisden
1478:
1475:
1472:
1467:
1464:
1459:
1454:
1449:
1444:
1439:
1434:
1431:
1426:
1424:Andrew Pollard
1421:
1418:
1413:
1408:
1403:
1398:
1393:
1388:
1385:
1380:
1375:
1372:
1367:
1362:
1360:Duncan Lorimer
1357:
1355:Chwee-Teck Lim
1352:
1349:
1344:
1343:David Komander
1341:
1336:
1331:
1328:
1323:
1318:
1313:
1308:
1303:
1301:Maria Harrison
1298:
1296:Anjali Goswami
1293:
1288:
1283:
1278:
1273:
1268:
1263:
1258:
1253:
1248:
1243:
1240:
1235:
1232:
1227:
1222:
1217:
1212:
1209:
1204:
1199:
1194:
1191:
1188:
1183:
1178:
1177:Simon Aldridge
1174:
1172:
1168:
1167:
1154:
1152:
1151:
1144:
1137:
1129:
1121:
1120:
1095:
1077:
1052:
1040:acmedsci.ac.uk
1027:
1002:
977:
966:. 20 July 2017
951:
925:
899:
854:(7): 982–993.
834:
779:
742:(2): 144–151.
722:
687:(2): 249–254.
667:
630:(2): 384–390.
610:
575:(2): 188–193.
555:
530:
504:
490:
478:www.gmc-uk.org
465:
439:ccpp.cam.ac.uk
423:
397:
396:
394:
391:
362:
359:
324:
321:
276:
273:
264:
261:
238:Wellcome Trust
229:
228:
209:
205:
204:
191:
187:
186:
177:
173:
172:
169:
165:
164:
162:Leeds, England
161:
157:
153:
152:
147:
144:
135:
134:
58:poorly sourced
31:
29:
22:
15:
13:
10:
9:
6:
4:
3:
2:
1696:
1685:
1684:Living people
1682:
1680:
1677:
1675:
1672:
1670:
1667:
1665:
1662:
1660:
1657:
1655:
1652:
1650:
1647:
1645:
1642:
1640:
1637:
1636:
1634:
1619:
1618:Cesar Victora
1616:
1614:
1611:
1609:
1606:
1603:
1601:
1598:
1596:
1593:
1591:
1588:
1586:
1583:
1580:
1577:
1574:
1572:
1569:
1567:
1564:
1562:
1559:
1557:
1556:Anthony Fauci
1554:
1552:
1549:
1547:
1544:
1542:
1539:
1537:
1534:
1532:
1531:Rene Bernards
1529:
1527:
1524:
1522:
1519:
1518:
1516:
1512:
1506:
1503:
1501:
1498:
1497:
1495:
1491:
1485:
1482:
1479:
1477:Glynn Winskel
1476:
1473:
1471:
1468:
1466:Patrick Unwin
1465:
1463:
1462:Sarah Tabrizi
1460:
1458:
1455:
1453:
1450:
1448:
1445:
1443:
1440:
1438:
1435:
1433:Keith Ridgway
1432:
1430:
1427:
1425:
1422:
1419:
1417:
1414:
1412:
1409:
1407:
1404:
1402:
1401:Francis Nimmo
1399:
1397:
1394:
1392:
1389:
1386:
1384:
1383:Tamsin Mather
1381:
1379:
1376:
1373:
1371:
1370:Barbara Maher
1368:
1366:
1363:
1361:
1358:
1356:
1353:
1350:
1348:
1345:
1342:
1340:
1339:Simon Knowles
1337:
1335:
1332:
1329:
1327:
1324:
1322:
1319:
1317:
1314:
1312:
1309:
1307:
1304:
1302:
1299:
1297:
1294:
1292:
1289:
1287:
1284:
1282:
1279:
1277:
1274:
1272:
1269:
1267:
1264:
1262:
1259:
1257:
1254:
1252:
1249:
1247:
1246:Barry Dickson
1244:
1241:
1239:
1236:
1234:Andrew Carter
1233:
1231:
1228:
1226:
1223:
1221:
1218:
1216:
1213:
1210:
1208:
1205:
1203:
1200:
1198:
1195:
1193:David Bentley
1192:
1190:David Bentley
1189:
1187:
1184:
1182:
1179:
1176:
1175:
1173:
1169:
1165:
1161:
1160:Royal Society
1157:
1150:
1145:
1143:
1138:
1136:
1131:
1130:
1127:
1109:
1108:Royal Society
1105:
1099:
1096:
1091:
1087:
1081:
1078:
1066:
1062:
1056:
1053:
1041:
1037:
1031:
1028:
1016:
1012:
1006:
1003:
991:
987:
981:
978:
965:
961:
955:
952:
940:
936:
929:
926:
913:
909:
903:
900:
895:
891:
887:
883:
878:
873:
869:
865:
861:
857:
853:
849:
845:
838:
835:
830:
826:
822:
818:
814:
810:
806:
802:
798:
794:
790:
783:
780:
775:
771:
766:
761:
757:
753:
749:
745:
741:
737:
733:
726:
723:
718:
714:
710:
706:
702:
698:
694:
690:
686:
682:
678:
671:
668:
663:
659:
654:
649:
645:
641:
637:
633:
629:
625:
621:
614:
611:
606:
602:
598:
594:
590:
586:
582:
578:
574:
570:
566:
559:
556:
544:
540:
534:
531:
518:
514:
508:
505:
500:
494:
491:
479:
475:
469:
466:
461:
455:
440:
436:
432:
427:
424:
412:
408:
402:
399:
392:
390:
388:
384:
380:
376:
372:
368:
360:
358:
356:
352:
348:
342:
339:
337:
332:
330:
322:
320:
316:
313:
308:
306:
302:
298:
293:
291:
290:neurogenetics
286:
282:
274:
272:
270:
262:
260:
258:
254:
249:
247:
243:
239:
235:
226:
210:
206:
202:
199:
196:
192:
188:
185:
181:
178:
174:
170:
166:
158:
154:
150:
142:
139:
131:
128:
120:
109:
106:
102:
99:
95:
92:
88:
85:
81:
78: –
77:
73:
72:Find sources:
66:
62:
59:
55:
51:
45:
44:
40:
35:
30:
21:
20:
1608:Erin Schuman
1600:Ares Rosakis
1590:Jian-Wei Pan
1585:Kyoko Nozaki
1575:Michael Mann
1566:Ruth Lehmann
1447:Simon Segars
1442:Stuart Rowan
1420:José Penadés
1396:Graham Moore
1391:Pat Monaghan
1378:Ivan Marusic
1347:Daniela Kühn
1316:David Hodell
1261:Paul Elliott
1256:Aled Edwards
1237:
1225:Brian Cantor
1211:Martin Blunt
1111:. Retrieved
1107:
1098:
1089:
1080:
1068:. Retrieved
1064:
1055:
1043:. Retrieved
1039:
1030:
1018:. Retrieved
1014:
1005:
993:. Retrieved
989:
980:
968:. Retrieved
963:
954:
942:. Retrieved
938:
928:
916:. Retrieved
911:
902:
851:
847:
837:
796:
792:
782:
739:
735:
725:
684:
680:
670:
627:
623:
613:
572:
568:
558:
546:. Retrieved
542:
533:
521:. Retrieved
516:
507:
493:
481:. Retrieved
477:
468:
442:. Retrieved
438:
426:
414:. Retrieved
410:
401:
364:
355:Chris Whitty
343:
340:
333:
326:
317:
312:mitochondria
309:
294:
278:
266:
250:
233:
232:
200:
197:
194:
138:
123:
114:
104:
97:
90:
83:
71:
60:
43:verification
36:
1679:1968 births
1581:William Nix
1526:Adriaan Bax
1411:Adrian Owen
1326:Peter Horby
1242:Yanick Crow
1162:elected in
1633:Categories
1595:Aviv Regev
1437:Tom Rodden
1416:Lloyd Peck
1406:Sarah Otto
1351:Eric Lauga
1311:Laura Herz
1266:Alan Evans
1251:Jo Dunkley
1207:Helen Blau
1181:John Aston
393:References
323:Leadership
87:newspapers
939:orcid.org
894:234768578
868:1061-4036
829:182457179
821:0036-8075
756:1465-7392
717:205344980
701:1061-4036
644:0964-6906
589:0364-5134
389:in 2024.
285:neurology
168:Education
117:July 2024
39:citations
1493:Honorary
1452:Yang Shi
1286:Toby Gee
1070:1 August
1045:1 August
1020:1 August
995:1 August
970:1 August
944:1 August
918:1 August
886:34002094
774:29335530
709:18223651
662:23077218
605:38326060
597:10939569
548:1 August
523:1 August
483:1 August
454:cite web
444:1 August
416:1 August
347:COVID-19
244:and the
215:.mrc-mbu
65:libelous
1514:Foreign
1171:Fellows
1158:of the
1156:Fellows
933:ORCID.
877:7611844
801:Bibcode
793:Science
765:6551220
653:3526165
208:Website
101:scholar
1113:18 May
1015:GOV.UK
990:GOV.UK
964:GOV.UK
892:
884:
874:
866:
827:
819:
772:
762:
754:
715:
707:
699:
660:
650:
642:
603:
595:
587:
474:"Home"
190:Awards
103:
96:
89:
82:
74:
890:S2CID
825:S2CID
713:S2CID
601:S2CID
108:JSTOR
94:books
32:This
1164:2024
1115:2024
1072:2021
1047:2021
1022:2021
997:2021
972:2021
946:2021
920:2021
882:PMID
864:ISSN
817:ISSN
770:PMID
752:ISSN
705:PMID
697:ISSN
658:PMID
640:ISSN
593:PMID
585:ISSN
550:2021
525:2021
485:2021
460:link
446:2021
418:2021
217:.cam
156:Born
80:news
41:for
872:PMC
856:doi
809:doi
797:364
760:PMC
744:doi
689:doi
648:PMC
632:doi
577:doi
221:.uk
219:.ac
213:www
149:FRS
1635::
1106:.
1088:.
1063:.
1038:.
1013:.
988:.
962:.
937:.
910:.
888:.
880:.
870:.
862:.
852:53
850:.
846:.
823:.
815:.
807:.
795:.
791:.
768:.
758:.
750:.
740:20
738:.
734:.
711:.
703:.
695:.
685:40
683:.
679:.
656:.
646:.
638:.
628:22
626:.
622:.
599:.
591:.
583:.
573:48
571:.
567:.
541:.
515:.
476:.
456:}}
452:{{
437:.
409:.
182:,
52:.
1148:e
1141:t
1134:v
1117:.
1092:.
1074:.
1049:.
1024:.
999:.
974:.
948:.
922:.
896:.
858::
831:.
811::
803::
776:.
746::
719:.
691::
664:.
634::
607:.
579::
552:.
527:.
487:.
462:)
448:.
420:.
130:)
124:(
119:)
115:(
105:·
98:·
91:·
84:·
67:.
46:.
Text is available under the Creative Commons Attribution-ShareAlike License. Additional terms may apply.