Knowledge (XXG)

Penicilloic acid

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203: 24: 460: 104: 501: 242: 412:. To determine whether treatment with a β-lactam is safe when an allergy is noted, patient history regarding severity of previous reaction is essential. 438: 494: 530: 217: 550: 520: 487: 545: 226:
InChI=1S/C9H14N2O5S/c1-9(2)5(8(15)16)11-6(17-9)4(7(13)14)10-3-12/h3-6,11H,1-2H3,(H,10,12)(H,13,14)(H,15,16)/t4-,5-,6+/m0/s1
323: 160: 535: 181: 433:. Lippincott's Illustrated Reviews (5th ed.). Philadelphia: Lippincott Williams & Wilkins. p. 386. 525: 409: 36: 198: 540: 70: 405: 378: 467: 434: 401:
who are treated with ampicillin, the incidence of maculopapular rash approaches 100 percent.
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Approximately five percent of patients have some kind of reaction, ranging from
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is any of several acids which are obtained from the penicillins by the
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Except where otherwise noted, data are given for materials in their
103: 93: 366:, penicilloic acid, which reacts with proteins and serves as a 186: 475: 49:)-2--5,5-dimethyl-1,3-thiazolidine-4-carboxylic acid 362:determinant of penicillin hypersensitivity is its 148: 79: 495: 8: 354:is the most important adverse effect of the 502: 488: 389:(marked swelling of the lips, tongue, and 201: 123: 15: 168: 421: 247: 222: 197: 229:Key: OPEGYZAATHKDEM-HCWXCVPCSA-N 7: 456: 454: 139: 474:. You can help Knowledge (XXG) by 14: 458: 381:(the most common rash seen with 283: 277: 22: 320:(at 25 °C , 100 kPa). 250:CC1((N(S1)(C(=O)O)NC=O)C(=O)O)C 295: 289: 271: 1: 346:ring (as by the action of a 429:Ferrier, Denise R. (2011). 567: 531:2,3-Diaminopropionic acids 453: 314: 258: 238: 213: 63: 55: 35: 30: 21: 551:Molecular biology stubs 521:Human drug metabolites 397:. Among patients with 546:Secondary amino acids 385:hypersensitivity) to 37:Systematic IUPAC name 410:β-lactam antibiotics 310: g·mol 18: 536:Dicarboxylic acids 406:allergic reactions 379:maculopapular rash 324:Infobox references 16: 483: 482: 468:molecular biology 440:978-81-8473-573-4 332:Chemical compound 330: 329: 182:CompTox Dashboard 105:Interactive image 17:Penicilloic acid 558: 504: 497: 490: 462: 455: 445: 444: 426: 408:occur among the 352:Hypersensitivity 336:Penicilloic acid 309: 297: 291: 285: 279: 273: 266:Chemical formula 206: 205: 190: 188: 172: 152: 141: 127: 107: 83: 58:Penicilloic acid 26: 19: 566: 565: 561: 560: 559: 557: 556: 555: 511: 510: 509: 508: 451: 449: 448: 441: 428: 427: 423: 418: 372:immune reaction 342:opening of the 333: 326: 321: 307: 294: 288: 282: 276: 268: 254: 251: 246: 245: 234: 231: 230: 227: 221: 220: 209: 191: 184: 175: 155: 142: 130: 110: 97: 86: 73: 59: 51: 50: 12: 11: 5: 564: 562: 554: 553: 548: 543: 538: 533: 528: 523: 513: 512: 507: 506: 499: 492: 484: 481: 480: 463: 447: 446: 439: 420: 419: 417: 414: 348:beta-lactamase 331: 328: 327: 322: 318:standard state 315: 312: 311: 305: 299: 298: 292: 286: 280: 274: 269: 264: 261: 260: 256: 255: 253: 252: 249: 241: 240: 239: 236: 235: 233: 232: 228: 225: 224: 216: 215: 214: 211: 210: 208: 207: 199:DTXSID60911623 194: 192: 180: 177: 176: 174: 173: 165: 163: 157: 156: 154: 153: 145: 143: 135: 132: 131: 129: 128: 120: 118: 112: 111: 109: 108: 100: 98: 91: 88: 87: 85: 84: 76: 74: 69: 66: 65: 61: 60: 57: 53: 52: 40: 39: 33: 32: 28: 27: 13: 10: 9: 6: 4: 3: 2: 563: 552: 549: 547: 544: 542: 539: 537: 534: 532: 529: 527: 526:Thiazolidines 524: 522: 519: 518: 516: 505: 500: 498: 493: 491: 486: 485: 479: 477: 473: 470:article is a 469: 464: 461: 457: 452: 442: 436: 432: 425: 422: 415: 413: 411: 407: 402: 400: 399:mononucleosis 396: 392: 388: 384: 380: 375: 373: 369: 365: 361: 357: 353: 349: 345: 341: 337: 325: 319: 313: 306: 304: 301: 300: 270: 267: 263: 262: 257: 248: 244: 237: 223: 219: 212: 204: 200: 196: 195: 193: 183: 179: 178: 171: 167: 166: 164: 162: 159: 158: 151: 147: 146: 144: 138: 134: 133: 126: 122: 121: 119: 117: 114: 113: 106: 102: 101: 99: 95: 90: 89: 82: 78: 77: 75: 72: 68: 67: 62: 54: 48: 44: 38: 34: 29: 25: 20: 476:expanding it 465: 450: 431:Pharmacology 430: 424: 403: 376: 370:to cause an 358:. The major 335: 334: 64:Identifiers 56:Other names 46: 42: 395:anaphylaxis 391:periorbital 356:penicillins 259:Properties 541:Formamides 515:Categories 416:References 393:area) and 387:angioedema 383:ampicillin 364:metabolite 340:hydrolytic 303:Molar mass 170:3A8ULT6HAQ 116:ChemSpider 92:3D model ( 81:64527-07-7 71:CAS Number 360:antigenic 150:52921568 137:PubChem 437:  404:Cross- 368:hapten 344:lactam 308:262.28 243:SMILES 125:393260 31:Names 466:This 218:InChI 94:JSmol 472:stub 435:ISBN 161:UNII 374:. 350:). 187:EPA 140:CID 517:: 281:14 45:,4 41:(2 503:e 496:t 489:v 478:. 443:. 296:S 293:5 290:O 287:2 284:N 278:H 275:9 272:C 189:) 185:( 96:) 47:S 43:R

Index

Structure of penicilloic acid
Systematic IUPAC name
CAS Number
64527-07-7
JSmol
Interactive image
ChemSpider
393260
PubChem
52921568
UNII
3A8ULT6HAQ
CompTox Dashboard
DTXSID60911623
Edit this at Wikidata
InChI
SMILES
Chemical formula
Molar mass
standard state
Infobox references
hydrolytic
lactam
beta-lactamase
Hypersensitivity
penicillins
antigenic
metabolite
hapten
immune reaction

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