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Pipemidic acid

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400: 377: 1581: 25: 131: 161: 644: 143: 483: 469: 1622: 609: 1540: 637: 751: 696: 503: 108: 610:"Disabling and potentially permanent side effects lead to suspension or restrictions of quinolone and fluoroquinolone antibiotics" 1651: 630: 194: 42: 1641: 89: 46: 61: 1615: 987: 1476: 276: 1557: 356: 68: 1646: 511:
InChI=1S/C14H17N5O3/c1-2-18-8-10(13(21)22)11(20)9-7-16-14(17-12(9)18)19-5-3-15-4-6-19/h7-8,15H,2-6H2,1H3,(H,21,22)
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8-Ethyl-5-oxo-2-piperazin-1-yl-5,8-dihydropyridopyrimidine-6-carboxylic acid
147: 130: 1150: 937: 714: 538: 1023: 231: 336: 537:, which display some overlap in mechanism of action with analogous 305: 468: 459: 316: 296: 626: 1461: 18: 361: 569:
of pipemidic acid has been suspended throughout the EU.
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You can help Knowledge (XXG) by 14: 1579: 429: 423: 23: 516:Key:JOHZPMXAZQZXHR-UHFFFAOYSA-N 34:needs additional citations for 586:"Pipemidic Acid - MeSH - NCBI" 435: 417: 1: 988:Trimethoprim/sulfamethoxazole 993:Ormetoprim/sulfadimethoxine 1673: 1574: 407:Chemical and physical data 1535: 1003:Pyrimethamine/sulfadoxine 614:European Medicines Agency 499: 479: 190: 128: 154:International Drug Names 1652:1-Piperazinyl compounds 567:marketing authorization 1591:-related article is a 902:Sulfamethoxypyridazine 551:gram positive bacteria 1642:Quinolone antibiotics 1375:Newer non-fluorinated 1012:Other DHPS inhibitors 998:Pyrimethamine/dapsone 825:Succinylsulfathiazole 821:Phthalylsulfathiazole 705:2,4-Diaminopyrimidine 799:Acetyl sulfisoxazole 658:inhibit nucleic acid 590:www.ncbi.nlm.nih.gov 43:improve this article 1174:Alalevonadifloxacin 841:Intermediate-acting 529:is a member of the 125: 1562:Never to phase III 1063:thereby inhibiting 1051:(inhibit bacterial 897:Sulfametoxydiazine 685:thereby inhibiting 678:(inhibit bacterial 563:urinary infections 553:. It was used for 1647:Pyridopyrimidines 1604: 1603: 1572: 1571: 1531: 1530: 1456: 1455: 1419: 1418: 1370: 1369: 1042: 1041: 976: 975: 681:purine metabolism 524: 523: 470:Interactive image 357:CompTox Dashboard 119: 118: 111: 93: 16:Chemical compound 1664: 1657:Antibiotic stubs 1625: 1618: 1611: 1583: 1576: 1468: 1435: 1170:Levonadifloxacin 1129: 1124:Fluoroquinolones 1072: 877:Sulfadimethoxine 849:Sulfamethoxazole 770:Sulfaisodimidine 758: 693: 647: 640: 633: 624: 618: 617: 616:. 11 March 2019. 606: 600: 599: 597: 596: 582: 555:gastrointestinal 531:pyridopyrimidine 472: 452: 437: 431: 425: 419: 402: 391: 380: 379: 365: 363: 348: 328: 308: 288: 268: 248: 238: 237: 223: 177: 156: 133: 126: 124: 114: 107: 103: 100: 94: 92: 58:"Pipemidic acid" 51: 27: 19: 1672: 1671: 1667: 1666: 1665: 1663: 1662: 1661: 1632: 1631: 1630: 1629: 1573: 1568: 1567: 1552:Clinical trials 1527: 1509: 1475: 1452: 1428: 1415: 1391: 1366: 1313: 1241: 1193: 1118: 1066:DNA replication 1064: 1062: 1056: 1052: 1050: 1038: 1007: 972: 931:Other/ungrouped 926: 892:Sulfametomidine 863: 835: 749: 741: 688: 686: 684: 679: 677: 669: 651: 621: 608: 607: 603: 594: 592: 584: 583: 579: 575: 520: 517: 512: 507: 506: 495: 492: 487: 486: 475: 450: 440: 434: 428: 422: 383: 359: 351: 331: 311: 291: 271: 251: 234: 226: 206: 203: 198: 197: 181: 115: 104: 98: 95: 52: 50: 40: 28: 17: 12: 11: 5: 1670: 1668: 1660: 1659: 1654: 1649: 1644: 1634: 1633: 1628: 1627: 1620: 1613: 1605: 1602: 1601: 1587:This systemic 1584: 1570: 1569: 1566: 1565: 1564: 1563: 1560: 1549: 1543: 1537: 1536: 1533: 1532: 1529: 1528: 1526: 1525: 1519: 1517: 1511: 1510: 1508: 1507: 1502: 1497: 1492: 1487: 1481: 1479: 1477:RNA polymerase 1465: 1458: 1457: 1454: 1453: 1451: 1450: 1444: 1442: 1439:Nitroimidazole 1432: 1421: 1420: 1417: 1416: 1414: 1413: 1407:Aminocoumarins 1403: 1401: 1393: 1392: 1390: 1389: 1384: 1378: 1376: 1372: 1371: 1368: 1367: 1365: 1364: 1359: 1354: 1349: 1344: 1339: 1334: 1329: 1323: 1321: 1315: 1314: 1312: 1311: 1309:Alatrofloxacin 1302: 1297: 1292: 1287: 1282: 1277: 1272: 1267: 1262: 1257: 1251: 1249: 1247:4th generation 1243: 1242: 1240: 1239: 1234: 1229: 1224: 1219: 1214: 1209: 1203: 1201: 1199:3rd generation 1195: 1194: 1192: 1191: 1186: 1181: 1176: 1163: 1158: 1153: 1148: 1143: 1137: 1135: 1133:2nd generation 1126: 1120: 1119: 1117: 1116: 1111: 1109:Piromidic acid 1106: 1104:Pipemidic acid 1101: 1096: 1094:Nalidixic acid 1091: 1086: 1080: 1078: 1076:1st generation 1069: 1044: 1043: 1040: 1039: 1037: 1036: 1031: 1026: 1021: 1015: 1013: 1009: 1008: 1006: 1005: 1000: 995: 990: 984: 982: 978: 977: 974: 973: 971: 970: 965: 960: 958:Sulfaguanidine 955: 953:Sulfadicramide 950: 945: 940: 934: 932: 928: 927: 925: 924: 919: 917:Sulfaphenazole 914: 909: 904: 899: 894: 889: 884: 879: 873: 871: 865: 864: 862: 861: 856: 851: 845: 843: 837: 836: 834: 833: 828: 814: 813: 812: 802: 792: 782: 777: 775:Sulfamethizole 772: 766: 764: 755: 752:DHPS inhibitor 743: 742: 740: 739: 738: 737: 732: 727: 722: 717: 712: 701: 699: 697:DHFR inhibitor 690: 671: 670: 654:Antibacterials 652: 650: 649: 642: 635: 627: 620: 619: 601: 576: 574: 571: 535:antibacterials 527:Pipemidic acid 522: 521: 519: 518: 515: 513: 510: 502: 501: 500: 497: 496: 494: 493: 490: 482: 481: 480: 477: 476: 474: 473: 465: 463: 455: 454: 448: 442: 441: 438: 432: 426: 420: 415: 409: 408: 404: 403: 393: 385: 384: 382: 381: 368: 366: 353: 352: 350: 349: 341: 339: 333: 332: 330: 329: 321: 319: 313: 312: 310: 309: 301: 299: 293: 292: 290: 289: 281: 279: 273: 272: 270: 269: 261: 259: 253: 252: 250: 249: 241: 239: 228: 227: 225: 224: 216: 214: 208: 207: 205: 204: 201: 193: 192: 191: 188: 187: 183: 182: 180: 179: 166: 164: 158: 157: 150: 140: 139: 135: 134: 123:Pipemidic acid 117: 116: 31: 29: 22: 15: 13: 10: 9: 6: 4: 3: 2: 1669: 1658: 1655: 1653: 1650: 1648: 1645: 1643: 1640: 1639: 1637: 1626: 1621: 1619: 1614: 1612: 1607: 1606: 1600: 1598: 1594: 1590: 1585: 1582: 1578: 1561: 1559: 1556: 1555: 1553: 1550: 1547: 1544: 1542: 1539: 1538: 1534: 1524: 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1102: 1100: 1099:Oxolinic acid 1097: 1095: 1092: 1090: 1087: 1085: 1082: 1081: 1079: 1077: 1073: 1070: 1067: 1060: 1055: 1054:topoisomerase 1049: 1045: 1035: 1032: 1030: 1027: 1025: 1022: 1020: 1019:Acediasulfone 1017: 1016: 1014: 1010: 1004: 1001: 999: 996: 994: 991: 989: 986: 985: 983: 979: 969: 966: 964: 961: 959: 956: 954: 951: 949: 946: 944: 943:Sulfacetamide 941: 939: 936: 935: 933: 929: 923: 920: 918: 915: 913: 912:Sulfamerazine 910: 908: 905: 903: 900: 898: 895: 893: 890: 888: 885: 883: 880: 878: 875: 874: 872: 870: 866: 860: 857: 855: 852: 850: 847: 846: 844: 842: 838: 832: 831:Sulfathiourea 829: 826: 822: 818: 817:Sulfathiazole 815: 811: 808: 807: 806: 805:Sulfanilamide 803: 800: 796: 795:Sulfafurazole 793: 790: 789:Sulfasalazine 786: 785:Sulfapyridine 783: 781: 780:Sulfadimidine 778: 776: 773: 771: 768: 767: 765: 763: 759: 756: 753: 748: 744: 736: 733: 731: 728: 726: 725:Pyrimethamine 723: 721: 718: 716: 713: 711: 708: 707: 706: 703: 702: 700: 698: 694: 691: 682: 676: 672: 667: 663: 659: 655: 648: 643: 641: 636: 634: 629: 628: 625: 615: 611: 605: 602: 591: 587: 581: 578: 572: 570: 568: 564: 560: 556: 552: 548: 547:gram negative 544: 540: 536: 532: 528: 514: 509: 505: 498: 489: 485: 478: 471: 467: 466: 464: 461: 456: 449: 447: 443: 416: 414: 410: 405: 401: 397: 394: 392: 390:ECHA InfoCard 386: 378: 374: 373:DTXSID3023479 370: 369: 367: 358: 354: 347: 343: 342: 340: 338: 334: 327: 323: 322: 320: 318: 314: 307: 303: 302: 300: 298: 294: 287: 283: 282: 280: 278: 274: 267: 263: 262: 260: 258: 254: 247: 243: 242: 240: 233: 229: 222: 218: 217: 215: 213: 209: 200: 196: 189: 184: 176: 171: 168: 167: 165: 163: 159: 155: 151: 149: 145: 141: 138:Clinical data 136: 132: 127: 113: 110: 102: 91: 88: 84: 81: 77: 74: 70: 67: 63: 60: –  59: 55: 54:Find sources: 48: 44: 38: 37: 32:This article 30: 26: 21: 20: 1597:expanding it 1586: 1515:Lipiarmycins 1362:Sarafloxacin 1352:Orbifloxacin 1337:Enrofloxacin 1327:Danofloxacin 1300:Sitafloxacin 1280:Moxifloxacin 1275:Gemifloxacin 1270:Finafloxacin 1265:Gatifloxacin 1260:Delafloxacin 1255:Besifloxacin 1237:Tosufloxacin 1232:Temafloxacin 1227:Sparfloxacin 1222:Pazufloxacin 1212:Balofloxacin 1207:Levofloxacin 1166:Nadifloxacin 1161:Lomefloxacin 1103: 981:Combinations 963:Sulfametrole 948:Sulfaclozine 854:Sulfadiazine 762:Short-acting 747:Sulfonamides 735:Trimethoprim 613: 604: 593:. Retrieved 589: 580: 541:-containing 526: 525: 105: 96: 86: 79: 72: 65: 53: 41:Please help 36:verification 33: 1548:from market 1523:Fidaxomicin 1495:Rifapentine 1448:Secnidazole 1441:derivatives 1382:Nemonoxacin 1342:Ibafloxacin 1290:Garenoxacin 1179:Norfloxacin 1029:Solasulfone 968:Sulfanitran 922:Sulfamazone 882:Sulfadoxine 869:Long-acting 859:Sulfamoxole 730:Tetroxoprim 710:Brodimoprim 687:DNA and RNA 675:Antifolates 453: g·mol 396:100.052.283 346:ChEMBL30116 326:CHEBI:75250 186:Identifiers 99:August 2014 1636:Categories 1589:antibiotic 1485:Rifampicin 1472:Rifamycins 1430:inhibitors 1411:Novobiocin 1387:Ozenoxacin 1332:Difloxacin 1319:Veterinary 1189:Rufloxacin 1184:Pefloxacin 1156:Fleroxacin 1089:Flumequine 1059:DNA gyrase 1048:Quinolones 907:Sulfaperin 720:Ormetoprim 689:synthesis) 595:2019-01-20 573:References 543:quinolones 458:3D model ( 446:Molar mass 286:LT12J5HVR8 257:ChemSpider 221:51940-44-4 212:CAS Number 195:IUPAC name 69:newspapers 1558:Phase III 1546:Withdrawn 1505:Rifalazil 1500:Rifaximin 1490:Rifabutin 1464:synthesis 1425:Anaerobic 1396:Related ( 1146:Ofloxacin 1114:Rosoxacin 1084:Cinoxacin 1034:Sulfoxone 887:Sulfalene 810:Prontosil 549:and some 533:class of 148:Drugs.com 1151:Enoxacin 938:Mafenide 715:Iclaprim 539:pyridone 162:ATC code 1057:and/or 1024:Dapsone 559:biliary 451:303.322 413:Formula 232:PubChem 178:) 172: ( 170:J01MB04 83:scholar 1541:WHO-EM 565:. The 561:, and 484:SMILES 337:ChEMBL 306:D08379 85:  78:  71:  64:  56:  656:that 504:InChI 460:JSmol 317:ChEBI 90:JSTOR 76:books 1593:stub 666:J01M 662:J01E 297:KEGG 277:UNII 266:4665 246:4831 144:AHFS 62:news 1462:RNA 1427:DNA 362:EPA 236:CID 175:WHO 45:by 1638:: 1554:: 1409:: 1398:DG 823:, 664:, 612:. 588:. 557:, 427:17 421:14 1624:e 1617:t 1610:v 1599:. 1474:/ 1400:) 1307:/ 1172:/ 1168:/ 1068:) 1061:, 827:) 819:( 801:) 797:( 791:) 787:( 754:) 750:( 683:, 668:) 660:( 646:e 639:t 632:v 598:. 462:) 439:3 436:O 433:5 430:N 424:H 418:C 364:) 360:( 146:/ 112:) 106:( 101:) 97:( 87:· 80:· 73:· 66:· 39:.

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"Pipemidic acid"
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AHFS
Drugs.com
International Drug Names
ATC code
J01MB04
WHO
IUPAC name
CAS Number
51940-44-4
PubChem
4831
ChemSpider
4665
UNII
LT12J5HVR8
KEGG
D08379
ChEBI

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