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Dysplasia

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415:. Hip dysplasia may occur at birth or develop in early life. Regardless, it does not typically produce symptoms in babies less than a year old. Occasionally one leg may be shorter than the other. The left hip is more often affected than the right. Complications without treatment can include 53: 45: 1606: 385:, resulting in formation of bone that is weak and prone to expansion. As a result, most complications result from fracture, deformity, functional impairment and pain. 565: 514: 126:, and cancerous forms. Various other dysplasias tend to be precancerous. The word's meanings thus cover a spectrum of histopathological variations. 288:
process. The term dysplasia is typically used when the cellular abnormality is restricted to the originating tissue, as in the case of an early,
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This article is about the noncancerous and precancerous changes in cells and tissues. For the clinical condition affecting the hip joint, see
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do not mature and therefore do not become healthy blood cells. Problems with blood cell formation result in some combination of
1095: 432: 92: 284:), with a corresponding decrease in the number and location of mature cells. Dysplasia is often indicative of an early 1601: 1126: 452:. The kidney consists of irregular cysts of varying sizes. Multicystic dysplastic kidney is a common type of renal 920: 368: 80: 955: 913: 315: 303: 88: 1596: 1565: 1172: 1048: 1012: 950: 509: 102:
senses of the term, dysplasia is sometimes differentiated from other categories of tissue change including
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or anatomical structure(s) resulting from such growth. Dysplasias on a mainly microscopic scale include
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where the socket portion does not fully cover the ball portion, resulting in an increased risk for
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Dysplasia, in which cell maturation and differentiation are delayed, can be contrasted with
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Epithelial dysplasia consists of an expansion of immature cells (such as cells of the
99: 595:. In Adam MP, Ardinger HH, Pagon RA, Wallace SE, Bean LJ, Mirzaa G, Amemiya A (eds.). 1585: 1438: 1251: 872: 469: 420: 399: 31: 1540: 1370: 1346: 1336: 1241: 1229: 1222: 813: 623: 225:(reduced functionality of an organ, with decrease in the number or volume of cells) 119: 17: 496: 1528: 1394: 1275: 1270: 1246: 1136: 1076: 935: 898: 821: 592: 378: 336: 228: 207: 183: 167: 103: 52: 1560: 1403: 1399: 1375: 1304: 1285: 1081: 930: 867: 831: 352: 332: 299: 234: 195: 189: 107: 1415: 1358: 1207: 1188: 1100: 986: 971: 836: 750: 723: 688: 416: 408: 285: 240: 201: 177: 155: 111: 72: 44: 38: 669: 660: 644:"Evaluation and Referral for Developmental Dysplasia of the Hip in Infants" 643: 604: 490: 1570: 1365: 1326: 1311: 1234: 1212: 1090: 981: 940: 925: 798: 790: 292: 281: 1443: 1408: 1388: 1265: 1202: 991: 976: 243:(any degenerative disorder resulting from improper or faulty nutrition) 222: 161: 192:(congenital below-average number of cells, especially when inadequate) 862: 794: 453: 445: 340: 328: 115: 63:
is any of various types of abnormal growth or development of cells (
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type are replaced by cells of another mature, differentiated type.
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Boyce AM, Florenzano P, de Castro LF, Collins MT (February 2015).
158:(structural differentiation loss within a cell or group of cells). 51: 43: 826: 374: 1161: 762: 351:. Some types have an increase in immature blood cells, called 118:. An exception is that the myelodysplasias include a range of 1157: 566:"Myelodysplastic Syndromes Treatment (PDQ®)–Patient Version" 444:) is a condition that results from the malformation of the 27:
Abnormal development, at macroscopic or microscopical level
626:. American Academy of Orthopaedic Surgeons. October 2013. 624:"Developmental Dislocation (Dysplasia) of the Hip (DDH)" 373:
Fibrous dysplasia of bone is a disorder where normal
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Archived from 7: 733:Robbins Pathologic Basis of Disease 642:Shaw BA, Segal LS (December 2016). 1491:Fluorescence in situ hybridization 210:(development of new cell function) 25: 456:disease, and it is a cause of an 1459:Oral and maxillofacial pathology 476:'bad' or 'difficult' and πλάσις 302:, in which cells of one mature, 164:(organ or part of organ missing) 1: 1096:Clonally transmissible cancer 438:Multicystic dysplastic kidney 433:Multicystic dysplastic kidney 427:Multicystic dysplastic kidney 93:multicystic dysplastic kidney 480:'formation'. The equivalent 1623: 1127:Index of oncology articles 430: 397: 366: 313: 176:(change in cell or tissue 170:(connective tissue growth) 138: 36: 29: 708:. London: W.B. Saunders. 706:Modern Surgical Pathology 534:"Definition of dysplasia" 407:is an abnormality of the 369:Fibrous dysplasia of bone 363:Fibrous dysplasia of bone 321:Myelodysplastic syndromes 198:(conversion in cell type) 81:fibrous dysplasia of bone 355:, in the bone marrow or 316:Myelodysplastic syndrome 310:Myelodysplastic syndrome 204:(abnormal proliferation) 186:(proliferation of cells) 89:myelodysplastic syndrome 37:Not to be confused with 1566:Microbiological culture 1196:Principles of pathology 1049:Prostate cancer staging 1013:Paraneoplastic syndrome 1087:Tumor suppressor genes 1054:Gleason grading system 1008:Precancerous condition 661:10.1542/peds.2016-3107 57: 49: 1529:Diagnostic immunology 1354:Programmed cell death 1322:Liquefactive necrosis 1106:Carcinogenic bacteria 846:Malignant progression 349:low white blood cells 98:In one of the modern 55: 48:Normal squamous cells 47: 1524:Medical microbiology 1519:Transfusion medicine 1476:Immunohistochemistry 1426:Anatomical pathology 1317:Coagulative necrosis 1059:Dukes classification 141:Epithelial dysplasia 135:Epithelial dysplasia 77:epithelial dysplasia 71:), and the abnormal 1481:Electron microscopy 1449:Molecular pathology 1327:Gangrenous necrosis 1259:Cellular adaptation 878:Sentinel lymph node 486:classical compounds 484:, in parallel with 341:low red blood cells 148:-plasia and -trophy 1602:Induced stem cells 1509:Clinical chemistry 1501:Clinical pathology 1486:Immunofluorescence 1454:Forensic pathology 1434:Surgical pathology 1342:Fibrinoid necrosis 926:Respiratory system 331:in which immature 58: 50: 18:Precancerous cells 1579: 1578: 1546:Mass spectrometry 1155: 1154: 1142:Cancer and nausea 1021: 1020: 858:Carcinoma in situ 742:978-0-7216-7335-6 715:978-0-7216-7253-3 572:on 5 October 2016 450:fetal development 413:joint dislocation 389:Macroscopic scale 381:is replaced with 327:) are a group of 278: 277: 130:Microscopic scale 100:histopathological 69:macroscopic scale 65:microscopic scale 16:(Redirected from 1614: 1466:Gross processing 1332:Caseous necrosis 1182: 1175: 1168: 1159: 956:Endocrine system 921:Digestive system 810: 783: 776: 769: 760: 754: 727: 691: 680: 674: 673: 663: 654:(6): e20163107. 639: 628: 627: 620: 609: 608: 588: 582: 581: 579: 577: 562: 551: 550: 548: 547: 530: 482:surface analysis 270: 263: 256: 145: 56:Dysplastic cells 21: 1622: 1621: 1617: 1616: 1615: 1613: 1612: 1611: 1582: 1581: 1580: 1575: 1534:Immunopathology 1514:Hematopathology 1495: 1420: 1191: 1186: 1156: 1151: 1110: 1063: 1017: 996: 960: 882: 841: 801: 787: 757: 743: 730: 716: 703: 699: 697:Further reading 694: 681: 677: 641: 640: 631: 622: 621: 612: 590: 589: 585: 575: 573: 564: 563: 554: 545: 543: 539:Merriam-Webster 532: 531: 527: 523: 506: 466: 435: 429: 419:, limping, and 402: 396: 391: 371: 365: 318: 312: 274: 143: 137: 132: 42: 35: 28: 23: 22: 15: 12: 11: 5: 1620: 1618: 1610: 1609: 1604: 1599: 1597:Histopathology 1594: 1584: 1583: 1577: 1576: 1574: 1573: 1568: 1563: 1558: 1556:Flow cytometry 1553: 1551:Chromatography 1548: 1543: 1537: 1536: 1531: 1526: 1521: 1516: 1511: 1505: 1503: 1497: 1496: 1494: 1493: 1488: 1483: 1478: 1473: 1471:Histopathology 1468: 1462: 1461: 1456: 1451: 1446: 1441: 1436: 1430: 1428: 1422: 1421: 1419: 1418: 1413: 1412: 1411: 1406: 1397: 1385: 1379: 1378: 1373: 1368: 1363: 1362: 1361: 1351: 1350: 1349: 1344: 1339: 1334: 1329: 1324: 1319: 1309: 1307: 1301: 1300: 1299: 1298: 1293: 1283: 1278: 1273: 1268: 1263: 1261: 1255: 1254: 1249: 1244: 1239: 1238: 1237: 1227: 1226: 1225: 1220: 1215: 1210: 1199: 1197: 1193: 1192: 1187: 1185: 1184: 1177: 1170: 1162: 1153: 1152: 1150: 1149: 1144: 1139: 1134: 1129: 1124: 1118: 1116: 1112: 1111: 1109: 1108: 1103: 1098: 1093: 1084: 1079: 1073: 1071: 1069:Carcinogenesis 1065: 1064: 1062: 1061: 1056: 1051: 1046: 1041: 1035: 1033: 1023: 1022: 1019: 1018: 1016: 1015: 1010: 1004: 1002: 998: 997: 995: 994: 989: 984: 979: 974: 968: 966: 962: 961: 959: 958: 953: 951:Nervous system 948: 943: 938: 933: 928: 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461: 459: 455: 451: 447: 443: 439: 434: 426: 424: 422: 421:low back pain 418: 414: 410: 406: 405:Hip dysplasia 401: 400:Hip dysplasia 394:Hip dysplasia 393: 388: 386: 384: 380: 376: 370: 362: 360: 358: 354: 350: 346: 345:low platelets 342: 338: 334: 330: 326: 322: 317: 309: 307: 305: 301: 296: 294: 291: 287: 283: 271: 266: 264: 259: 257: 252: 251: 249: 248: 242: 239: 236: 233: 230: 227: 224: 221: 218: 217: 216: 215: 209: 206: 203: 200: 197: 194: 191: 188: 185: 182: 179: 175: 172: 169: 166: 163: 160: 157: 154: 153: 152: 151: 146: 142: 134: 129: 127: 125: 121: 117: 113: 109: 105: 101: 96: 94: 90: 86: 85:hip dysplasia 82: 78: 74: 70: 67:) or organs ( 66: 62: 54: 46: 40: 33: 32:Hip dysplasia 19: 1541:Enzyme assay 1387: 1382: 1371:Karyorrhexis 1347:Myocytolysis 1337:Fat necrosis 1280: 1242:Inflammation 1230:Hemodynamics 1223:Pathogenesis 852: 789:Overview of 732: 705: 682: 678: 651: 647: 597:Gene Reviews 596: 586: 574:. Retrieved 570:the original 544:. Retrieved 537: 528: 510:Pleomorphism 495: 489: 477: 473: 467: 460:in infants. 441: 437: 436: 404: 403: 372: 324: 320: 319: 297: 289: 279: 173: 124:precancerous 97: 60: 59: 1395:Hemosiderin 1276:Hyperplasia 1271:Hypertrophy 1247:Cell damage 1137:Cancer pain 1077:Cancer cell 822:Hyperplasia 337:bone marrow 333:blood cells 229:Hypertrophy 208:Prosoplasia 184:Hyperplasia 168:Desmoplasia 104:hyperplasia 1586:Categories 1561:Blood bank 1404:Lipofuscin 1400:Lipochrome 1376:Karyolysis 1305:Cell death 1286:Metaplasia 1082:Carcinogen 946:Urogenital 887:Topography 868:Metastasis 832:Pseudocyst 806:Conditions 648:Pediatrics 576:27 October 546:2019-09-09 541:dictionary 521:References 300:metaplasia 286:neoplastic 235:Hypotrophy 196:Metaplasia 190:Hypoplasia 108:metaplasia 1416:Steatosis 1359:Apoptosis 1296:Glandular 1281:Dysplasia 1213:Neoplasia 1208:Infection 1189:Pathology 1101:Oncovirus 1091:oncogenes 1044:Ann Arbor 987:Papilloma 972:Carcinoma 965:Histology 909:laryngeal 853:Dysplasia 837:Hamartoma 689:eMedicine 464:Etymology 417:arthritis 409:hip joint 241:Dystrophy 202:Neoplasia 178:phenotype 174:Dysplasia 156:Anaplasia 116:cancerous 112:neoplasia 73:histology 61:Dysplasia 39:Dyscrasia 1592:Oncology 1571:Serology 1366:Pyknosis 1312:Necrosis 1291:Squamous 1235:Ischemia 1122:Research 982:Blastoma 799:oncology 751:39465455 724:50244347 670:27940740 605:25719192 504:See also 293:neoplasm 282:ectoderm 1444:Autopsy 1409:Melanin 1389:pigment 1266:Atrophy 1203:Disease 1132:History 1031:grading 1027:Staging 992:Adenoma 977:Sarcoma 497:-plasia 448:during 335:in the 329:cancers 290:in-situ 223:Atrophy 162:Aplasia 863:Cancer 795:cancer 791:tumors 749:  739:  722:  712:  668:  603:  478:plasis 454:cystic 446:kidney 379:marrow 353:blasts 347:, and 120:benign 110:, and 91:, and 1218:Cause 1115:Misc. 1001:Other 941:Blood 488:, is 472:δυσ- 468:From 357:blood 1147:Diet 936:Skin 931:Bone 899:oral 827:Cyst 797:and 747:OCLC 737:ISBN 720:OCLC 710:ISBN 666:PMID 601:PMID 578:2016 491:dys- 474:dys- 442:MCDK 377:and 375:bone 79:and 1039:TNM 687:at 656:doi 652:138 325:MDS 1588:: 793:, 745:. 718:. 664:. 650:. 646:. 632:^ 613:^ 555:^ 536:. 500:. 494:+ 423:. 359:. 343:, 295:. 122:, 106:, 95:. 87:, 1402:/ 1181:e 1174:t 1167:v 1089:/ 1029:/ 782:e 775:t 768:v 753:. 726:. 672:. 658:: 607:. 580:. 549:. 440:( 323:( 269:e 262:t 255:v 180:) 41:. 34:. 20:)

Index

Precancerous cells
Hip dysplasia
Dyscrasia


microscopic scale
macroscopic scale
histology
epithelial dysplasia
fibrous dysplasia of bone
hip dysplasia
myelodysplastic syndrome
multicystic dysplastic kidney
histopathological
hyperplasia
metaplasia
neoplasia
cancerous
benign
precancerous
Epithelial dysplasia
Anaplasia
Aplasia
Desmoplasia
Dysplasia
phenotype
Hyperplasia
Hypoplasia
Metaplasia
Neoplasia

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