26:
1014:
278:
191:
210:
1071:
558:
1105:
652:
322:
as oxidant and incorporation of two atoms of oxygen into the substrate (oxygenases). The oxygen incorporated need not be derived from O
435:"Anaerobic enzymeâ‹…substrate structures provide insight into the reaction mechanism of the copper-dependent quercetin 2,3-dioxygenase"
733:
203:
154:
1064:
130:
889:
1115:
642:
618:
604:
551:
657:
613:
599:
391:
387:
383:
379:
375:
371:
1004:
874:
148:
1057:
990:
977:
964:
951:
938:
925:
912:
691:
672:
627:
584:
884:
838:
781:
575:
285:
236:
135:
41:
1100:
786:
544:
343:
215:
123:
263:
1095:
807:
726:
879:
647:
637:
499:
446:
151:
58:
75:
1090:
843:
300:
53:
25:
1110:
776:
700:
662:
525:
517:
474:
421:
367:
363:
251:
142:
111:
30:
Crystal structure of quercetin 2,3-dioxygenase from pdb entry 1H1I with quercetin and copper.
822:
817:
791:
719:
536:
507:
464:
454:
413:
87:
869:
853:
766:
327:
304:
46:
503:
450:
1041:
1018:
907:
848:
567:
315:
186:
512:
487:
469:
434:
417:
166:
1084:
812:
771:
161:
529:
761:
594:
308:
985:
920:
756:
170:
1013:
681:
228:
959:
933:
571:
289:
247:
521:
488:"Bacillus subtilis YxaG is a novel Fe-containing quercetin 2,3-dioxygenase"
478:
459:
404:
Oka T, Simpson FJ (1971). "Quercetinase, a dioxygenase containing copper".
425:
239:
99:
1034:
118:
1037:
972:
742:
622:
608:
351:
293:
243:
198:
94:
82:
70:
946:
347:
106:
715:
540:
711:
280:
2-(3,4-dihydroxybenzoyloxy)-4,6-dihydroxybenzoate + CO + H
267:
1045:
303:
are 2-(3,4-dihydroxybenzoyloxy)-4,6-dihydroxybenzoate,
486:
Bowater L, Fairhurst SA, Just VJ, Bornemann S (2004).
1002:
266:
898:
862:
831:
800:
749:
690:
671:
583:
318:, specifically those acting on single donors with O
209:
197:
185:
180:
160:
141:
129:
117:
105:
93:
81:
69:
64:
52:
40:
35:
18:
272:
366:have been solved for this class of enzymes, with
334:(decyclizing). Other names in common use include
1065:
727:
552:
8:
1072:
1058:
734:
720:
712:
559:
545:
537:
177:
24:
511:
468:
458:
433:Steiner RA, Kalk KH, Dijkstra BW (2002).
265:
1009:
15:
314:This enzyme belongs to the family of
7:
1030:
1028:
332:quercetin:oxygen 2,3-oxidoreductase
653:4-Hydroxyphenylpyruvate dioxygenase
273:{\displaystyle \rightleftharpoons }
14:
1012:
1:
643:Homogentisate 1,2-dioxygenase
513:10.1016/S0014-5793(03)01439-X
418:10.1016/S0006-291X(71)80076-1
406:Biochem. Biophys. Res. Commun
1044:. You can help Knowledge by
619:Arachidonate 15-lipoxygenase
605:Arachidonate 12-lipoxygenase
439:Proc. Natl. Acad. Sci. U.S.A
658:Indoleamine 2,3-dioxygenase
614:Arachidonate 8-lipoxygenase
600:Arachidonate 5-lipoxygenase
1132:
1106:Enzymes of known structure
1027:
890:Michaelis–Menten kinetics
628:Linoleate 11-lipoxygenase
233:quercetin 2,3-dioxygenase
176:
23:
19:quercetin 2,3-dioxygenase
782:Diffusion-limited enzyme
330:of this enzyme class is
1040:-related article is a
460:10.1073/pnas.262506299
340:flavonol 2,4-oxygenase
274:
875:Eadie–Hofstee diagram
808:Allosteric regulation
587:: two atoms of oxygen
362:As of late 2007, six
275:
1116:Oxidoreductase stubs
885:Lineweaver–Burk plot
675:: one atom of oxygen
648:Cysteine dioxygenase
638:Catechol dioxygenase
299:, whereas its three
264:
504:2004FEBSL.557...45B
451:2002PNAS...9916625S
288:of this enzyme are
844:Enzyme superfamily
777:Enzyme promiscuity
701:Inositol oxygenase
682:Firefly luciferase
663:Chlorite dismutase
635:other dioxygenase:
364:crystal structures
358:Structural studies
270:
1053:
1052:
1000:
999:
709:
708:
252:chemical reaction
225:
224:
221:
220:
124:metabolic pathway
1123:
1074:
1067:
1060:
1029:
1017:
1016:
1008:
880:Hanes–Woolf plot
823:Enzyme activator
818:Enzyme inhibitor
792:Enzyme catalysis
736:
729:
722:
713:
561:
554:
547:
538:
533:
515:
482:
472:
462:
445:(26): 16625–30.
429:
370:accession codes
279:
277:
276:
271:
178:
28:
16:
1131:
1130:
1126:
1125:
1124:
1122:
1121:
1120:
1081:
1080:
1079:
1078:
1025:
1023:
1011:
1003:
1001:
996:
908:Oxidoreductases
894:
870:Enzyme kinetics
858:
854:List of enzymes
827:
796:
767:Catalytic triad
745:
740:
710:
705:
686:
667:
579:
568:Oxidoreductases
565:
485:
432:
403:
400:
360:
328:systematic name
325:
321:
316:oxidoreductases
297:
262:
261:
260:
31:
12:
11:
5:
1129:
1127:
1119:
1118:
1113:
1108:
1103:
1101:Copper enzymes
1098:
1093:
1083:
1082:
1077:
1076:
1069:
1062:
1054:
1051:
1050:
1022:
1021:
998:
997:
995:
994:
981:
968:
955:
942:
929:
916:
902:
900:
896:
895:
893:
892:
887:
882:
877:
872:
866:
864:
860:
859:
857:
856:
851:
846:
841:
835:
833:
832:Classification
829:
828:
826:
825:
820:
815:
810:
804:
802:
798:
797:
795:
794:
789:
784:
779:
774:
769:
764:
759:
753:
751:
747:
746:
741:
739:
738:
731:
724:
716:
707:
706:
704:
703:
697:
695:
688:
687:
685:
684:
678:
676:
669:
668:
666:
665:
660:
655:
650:
645:
640:
631:
630:
625:
616:
611:
602:
590:
588:
581:
580:
572:monooxygenases
566:
564:
563:
556:
549:
541:
535:
534:
483:
430:
399:
396:
359:
356:
342:. It has two
323:
319:
295:
284:Thus, the two
282:
281:
269:
258:
223:
222:
219:
218:
213:
207:
206:
201:
195:
194:
189:
183:
182:
174:
173:
164:
158:
157:
146:
139:
138:
133:
127:
126:
121:
115:
114:
109:
103:
102:
97:
91:
90:
85:
79:
78:
73:
67:
66:
62:
61:
56:
50:
49:
44:
38:
37:
33:
32:
29:
21:
20:
13:
10:
9:
6:
4:
3:
2:
1128:
1117:
1114:
1112:
1109:
1107:
1104:
1102:
1099:
1097:
1094:
1092:
1089:
1088:
1086:
1075:
1070:
1068:
1063:
1061:
1056:
1055:
1049:
1047:
1043:
1039:
1036:
1031:
1026:
1020:
1015:
1010:
1006:
992:
988:
987:
982:
979:
975:
974:
969:
966:
962:
961:
956:
953:
949:
948:
943:
940:
936:
935:
930:
927:
923:
922:
917:
914:
910:
909:
904:
903:
901:
897:
891:
888:
886:
883:
881:
878:
876:
873:
871:
868:
867:
865:
861:
855:
852:
850:
849:Enzyme family
847:
845:
842:
840:
837:
836:
834:
830:
824:
821:
819:
816:
814:
813:Cooperativity
811:
809:
806:
805:
803:
799:
793:
790:
788:
785:
783:
780:
778:
775:
773:
772:Oxyanion hole
770:
768:
765:
763:
760:
758:
755:
754:
752:
748:
744:
737:
732:
730:
725:
723:
718:
717:
714:
702:
699:
698:
696:
693:
689:
683:
680:
679:
677:
674:
670:
664:
661:
659:
656:
654:
651:
649:
646:
644:
641:
639:
636:
633:
632:
629:
626:
624:
620:
617:
615:
612:
610:
606:
603:
601:
598:
596:
592:
591:
589:
586:
582:
577:
573:
569:
562:
557:
555:
550:
548:
543:
542:
539:
531:
527:
523:
519:
514:
509:
505:
501:
498:(1–3): 45–8.
497:
493:
489:
484:
480:
476:
471:
466:
461:
456:
452:
448:
444:
440:
436:
431:
427:
423:
419:
415:
411:
407:
402:
401:
397:
395:
393:
389:
385:
381:
377:
373:
369:
365:
357:
355:
353:
349:
345:
341:
337:
333:
329:
317:
312:
310:
306:
302:
298:
291:
287:
257:quercetin + O
256:
255:
254:
253:
249:
245:
241:
238:
234:
230:
217:
214:
212:
208:
205:
202:
200:
196:
193:
190:
188:
184:
179:
175:
172:
168:
165:
163:
162:Gene Ontology
159:
156:
153:
150:
147:
144:
140:
137:
134:
132:
128:
125:
122:
120:
116:
113:
110:
108:
104:
101:
100:NiceZyme view
98:
96:
92:
89:
86:
84:
80:
77:
74:
72:
68:
63:
60:
57:
55:
51:
48:
45:
43:
39:
34:
27:
22:
17:
1096:Iron enzymes
1046:expanding it
1032:
1024:
986:Translocases
983:
970:
957:
944:
931:
921:Transferases
918:
905:
762:Binding site
634:
595:lipoxygenase
593:
495:
491:
442:
438:
409:
405:
361:
339:
336:quercetinase
335:
331:
313:
283:
232:
226:
88:BRENDA entry
757:Active site
76:IntEnz view
36:Identifiers
1091:EC 1.13.11
1085:Categories
960:Isomerases
934:Hydrolases
801:Regulation
412:(1): 1–5.
398:References
286:substrates
240:1.13.11.24
229:enzymology
145:structures
112:KEGG entry
59:9075-67-6
47:1.13.11.24
1111:Quercetin
839:EC number
492:FEBS Lett
344:cofactors
290:quercetin
268:⇌
248:catalyzes
65:Databases
863:Kinetics
787:Cofactor
750:Activity
530:45729959
522:14741339
479:12486225
301:products
242:) is an
216:proteins
204:articles
192:articles
149:RCSB PDB
1035:EC 1.13
1019:Biology
973:Ligases
743:Enzymes
694:: other
692:1.13.99
673:1.13.12
585:1.13.11
500:Bibcode
447:Bibcode
426:5579942
326:. The
171:QuickGO
136:profile
119:MetaCyc
54:CAS no.
1038:enzyme
1005:Portal
947:Lyases
623:ALOX15
609:ALOX12
528:
520:
477:
470:139194
467:
424:
390:, and
352:copper
307:, and
244:enzyme
199:PubMed
181:Search
167:AmiGO
155:PDBsum
95:ExPASy
83:BRENDA
71:IntEnz
42:EC no.
1033:This
899:Types
578:1.13)
526:S2CID
246:that
131:PRIAM
1042:stub
991:list
984:EC7
978:list
971:EC6
965:list
958:EC5
952:list
945:EC4
939:list
932:EC3
926:list
919:EC2
913:list
906:EC1
518:PMID
475:PMID
422:PMID
392:2H0V
388:1JUH
384:1H1M
380:1H1I
376:1GQH
372:1GQG
350:and
348:iron
338:and
292:and
250:the
231:, a
211:NCBI
152:PDBe
107:KEGG
508:doi
496:557
465:PMC
455:doi
414:doi
368:PDB
227:In
187:PMC
143:PDB
1087::
576:EC
570::
524:.
516:.
506:.
494:.
490:.
473:.
463:.
453:.
443:99
441:.
437:.
420:.
410:43
408:.
394:.
386:,
382:,
378:,
374:,
354:.
346::
311:.
305:CO
237:EC
169:/
1073:e
1066:t
1059:v
1048:.
1007::
993:)
989:(
980:)
976:(
967:)
963:(
954:)
950:(
941:)
937:(
928:)
924:(
915:)
911:(
735:e
728:t
721:v
621:/
607:/
597::
574:(
560:e
553:t
546:v
532:.
510::
502::
481:.
457::
449::
428:.
416::
324:2
320:2
309:H
296:2
294:O
259:2
235:(
Text is available under the Creative Commons Attribution-ShareAlike License. Additional terms may apply.
