242:
219:
116:
141:
1133:
directly due to decreased inhibition of the outward potassium current in states where magnesium is low. Conversely, magnesium deficiency alone is not likely to cause a state of hypokalemia. Sgk1 kinase has also been reported to phosphorylate ROMK, resulting in an increase of channels on the apical surface of the distal tubule. Sgk1 is in turn regulated by the mineralocorticoid receptor such an effect may contribute to the kaliuretic action of aldosterone.
248:
147:
1132:
The ROMK channels are inhibited by magnesium in the nephron's normal physiologic state. In states of hypokalemia (a state of potassium deficiency), concurrent magnesium deficiency results in a state of hypokalemia that may be more difficult to correct with potassium replacement alone. This may be
1066:
and probably plays an important role in potassium homeostasis. The encoded protein has a greater tendency to allow potassium to flow into a cell rather than out of a cell, which has (hence the term "inwardly rectifying" referring to corresponding currents in electrophysiology, but has limited
1662:
Kubo Y, Adelman JP, Clapham DE, Jan LY, Karschin A, Kurachi Y, Lazdunski M, Nichols CG, Seino S, Vandenberg CA (December 2005). "International Union of
Pharmacology. LIV. Nomenclature and molecular relationships of inwardly rectifying potassium channels".
1306:
Kubo Y, Adelman JP, Clapham DE, Jan LY, Karschin A, Kurachi Y, Lazdunski M, Nichols CG, Seino S, Vandenberg CA (December 2005). "International Union of
Pharmacology. LIV. Nomenclature and molecular relationships of inwardly rectifying potassium channels".
1424:
1700:
Brochard K, Boyer O, Blanchard A, Loirat C, Niaudet P, Macher MA, Deschenes G, Bensman A, Decramer S, Cochat P, Morin D, Broux F, Caillez M, Guyot C, Novo R, Jeunemaître X, Vargas-Poussou R (May 2009).
3287:
1279:
Yano H, Philipson LH, Kugler JL, Tokuyama Y, Davis EM, Le Beau MM, Nelson DJ, Bell GI, Takeda J (May 1994). "Alternative splicing of human inwardly rectifying K+ channel ROMK1 mRNA".
4197:
1228:
Ho K, Nichols CG, Lederer WJ, Lytton J, Vassilev PM, Kanazirska MV, Hebert SC (March 1993). "Cloning and expression of an inwardly rectifying ATP-regulated potassium channel".
3932:
3184:
3117:
1058:
are present in most mammalian cells, where they participate in a wide range of physiologic responses. The protein encoded by this gene is an integral membrane protein and
255:
154:
2468:
1820:"Heterozygous mutations of the gene for Kir 1.1 (ROMK) in antenatal Bartter syndrome presenting with transient hyperkalemia, evolving to a benign course"
702:
77:
683:
4128:
4111:
4106:
4101:
4096:
1781:
Nüsing RM, Pantalone F, Gröne HJ, Seyberth HW, Wegmann M (June 2005). "Expression of the potassium channel ROMK in adult and fetal human kidney".
4133:
3231:
2503:
1059:
4734:
1210:
1192:
4185:
3366:
4083:
3104:
2520:
942:
1950:"Expression of tetraspan protein CD63 activates protein-tyrosine kinase (PTK) and enhances the PTK-induced inhibition of ROMK channels"
241:
48:, KIR1.1, ROMK, ROMK1, potassium voltage-gated channel subfamily J member 1, potassium inwardly rectifying channel subfamily J member 1
3869:
2317:
Murthy M, Cope G, O'Shaughnessy KM (October 2008). "The acidic motif of WNK4 is crucial for its interaction with the K channel ROMK".
949:
2038:"Cell surface expression of the ROMK (Kir 1.1) channel is regulated by the aldosterone-induced kinase, SGK-1, and protein kinase A"
1565:"Cell surface expression of the ROMK (Kir 1.1) channel is regulated by the aldosterone-induced kinase, SGK-1, and protein kinase A"
218:
1355:
4462:
3461:
3239:
2555:
1179:
1158:
1072:
1068:
4484:
140:
115:
1175:
4693:
2604:
1904:
Nozu K, Fu XJ, Kaito H, Kanda K, Yokoyama N, Przybyslaw Krol R, Nakajima T, Kajiyama M, Iijima K, Matsuo M (August 2007).
2231:"Common variants in genes underlying monogenic hypertension and hypotension and blood pressure in the general population"
1154:
4059:
2971:
57:
4334:
1948:
Lin D, Kamsteeg EJ, Zhang Y, Jin Y, Sterling H, Yue P, Roos M, Duffield A, Spencer J, Caplan M, Wang WH (March 2008).
254:
153:
2512:
2496:
2229:
Tobin MD, Tomaszewski M, Braund PS, Hajat C, Raleigh SM, Palmer TM, Caulfield M, Burton PR, Samani NJ (June 2008).
1420:"Removal of sialic acid involving Klotho causes cell-surface retention of TRPV5 channel via binding to galectin-1"
247:
146:
4688:
2898:
2459:
1611:"Phosphorylation-regulated endoplasmic reticulum retention signal in the renal outer-medullary K+ channel (ROMK)"
4678:
2939:
2815:
2453:
1026:
747:
65:
1861:
Ji W, Foo JN, O'Roak BJ, Zhao H, Larson MG, Simon DB, Newton-Cheh C, State MW, Levy D, Lifton RP (May 2008).
4683:
728:
4714:
2706:
2693:
2680:
2660:
2647:
2612:
1063:
1124:, which is characterized by salt wasting, hypokalemic alkalosis, hypercalciuria, and low blood pressure.
4739:
2489:
129:
1017:
1.1) that transports potassium out of cells. It plays an important role in potassium recycling in the
2587:
2359:
1622:
1485:
1433:
1237:
1018:
44:
2481:
1738:"Structural changes in the cytoplasmic pore of the Kir1.1 channel during pHi-gating probed by FRET"
921:
854:
2449:
4054:
2930:
2577:
1936:
1806:
1688:
1332:
1261:
1105:
1083:
89:
1863:"Rare independent mutations in renal salt handling genes contribute to blood pressure variation"
925:
900:
896:
892:
888:
884:
858:
833:
829:
825:
821:
817:
2196:"Assembly and trafficking of a multiprotein ROMK (Kir 1.1) channel complex by PDZ interactions"
3092:
2430:
2401:"A comprehensive guide to the ROMK potassium channel: form and function in health and disease"
2387:
2334:
2305:
2262:
2217:
2182:
2137:
2102:
2059:
2024:
1981:
1928:
1892:
1849:
1798:
1769:
1724:
1680:
1650:
1586:
1545:
1504:
1461:
1400:
1324:
1288:
1253:
1055:
1010:
37:
1369:
Foster DB, Ho AS, Rucker J, Garlid AO, Chen L, Sidor A, Garlid KD, O'Rourke B (August 2012).
3861:
2842:
2420:
2412:
2377:
2367:
2326:
2295:
2287:
2252:
2242:
2207:
2172:
2162:
2127:
2092:
2084:
2049:
2014:
2006:
1971:
1961:
1920:
1882:
1874:
1839:
1831:
1790:
1759:
1749:
1714:
1672:
1640:
1630:
1576:
1535:
1494:
1451:
1441:
1390:
1382:
1316:
1245:
1121:
1101:
1087:
1079:
334:
265:
209:
164:
1906:"A novel mutation in KCNJ1 in a Bartter syndrome case diagnosed as pseudohypoaldosteronism"
85:
4397:
2537:
2073:"Regulation of renal outer medullary potassium channel and renal K(+) excretion by Klotho"
1047:. Multiple transcript variants encoding different isoforms have been found for this gene.
309:
2363:
1626:
1437:
1241:
4193:
2880:
2425:
2400:
2382:
2347:
2300:
2275:
2247:
2230:
2177:
2150:
2097:
2072:
2019:
1994:
1887:
1862:
1844:
1819:
1764:
1737:
1703:"Phenotype-genotype correlation in antenatal and neonatal variants of Bartter syndrome"
1645:
1610:
1456:
1419:
1395:
1370:
1905:
617:
612:
607:
602:
597:
581:
576:
571:
566:
550:
545:
540:
535:
530:
525:
4728:
4147:
3820:
2472:
512:
1940:
1810:
1692:
1336:
69:
4500:
3891:
1265:
1067:
physiological relevance). ROMK was identified as the pore-forming component of the
327:
106:
1386:
93:
4430:
4425:
4420:
4415:
4302:
4141:
2516:
2416:
2010:
1215:
National Center for
Biotechnology Information, U.S. National Library of Medicine
1197:
National Center for
Biotechnology Information, U.S. National Library of Medicine
1109:
2352:
Proceedings of the
National Academy of Sciences of the United States of America
2330:
1615:
Proceedings of the
National Academy of Sciences of the United States of America
1609:
O'Connell AD, Leng Q, Dong K, MacGregor GG, Giebisch G, Hebert SC (July 2005).
1425:
Proceedings of the
National Academy of Sciences of the United States of America
410:
4410:
3776:
3144:
3112:
2194:
Yoo D, Flagg TP, Olsen O, Raghuram V, Foskett JK, Welling PA (February 2004).
2151:"Regulation of ROMK channel and K+ homeostasis by kidney-specific WNK1 kinase"
1924:
1835:
1794:
226:
123:
73:
4495:
4405:
2372:
1754:
1635:
1481:"Regulation of ion channels by secreted Klotho: mechanisms and implications"
1446:
1022:
647:
470:
348:
293:
280:
192:
179:
81:
2434:
2391:
2348:"Antagonistic regulation of ROMK by long and kidney-specific WNK1 isoforms"
2338:
2309:
2266:
2221:
2212:
2195:
2186:
2167:
2141:
2106:
2088:
2063:
2054:
2037:
2036:
Yoo D, Kim BY, Campo C, Nance L, King A, Maouyo D, Welling PA (June 2003).
2028:
1985:
1966:
1949:
1932:
1896:
1853:
1802:
1773:
1728:
1684:
1654:
1590:
1581:
1564:
1563:
Yoo D, Kim BY, Campo C, Nance L, King A, Maouyo D, Welling PA (June 2003).
1549:
1540:
1523:
1508:
1465:
1404:
1328:
1292:
1257:
989:
984:
4508:
3856:
2835:
2830:
2825:
2820:
2752:
2747:
1719:
1702:
1095:
973:
792:
773:
4635:
4392:
4228:
2729:
2724:
2719:
1676:
1499:
1480:
1320:
1030:
759:
714:
2132:
2115:
1976:
1418:
Cha SK, Ortega B, Kurosu H, Rosenblatt KP, Kuro-O M, Huang CL (2008).
4312:
4307:
4041:
4036:
3982:
3977:
3793:
3781:
3771:
3766:
3754:
3749:
3744:
3631:
3626:
3621:
3513:
3449:
3444:
3439:
3434:
3429:
3424:
3419:
3354:
3349:
3339:
3334:
3329:
3280:
3275:
3265:
3260:
3137:
3132:
3127:
3122:
3028:
3023:
3018:
3008:
3003:
2993:
2988:
2918:
2913:
2908:
2903:
2806:
2801:
2796:
2791:
2779:
2774:
2769:
2764:
2673:
2640:
2635:
2630:
2625:
2291:
2257:
1249:
1091:
957:
669:
1878:
1371:"Mitochondrial ROMK channel is a molecular component of mitoK(ATP)"
4546:
4477:
4472:
4467:
4384:
4371:
4366:
4361:
4356:
4351:
4346:
4297:
4290:
4285:
4280:
4275:
4270:
4265:
4260:
4255:
4243:
4238:
4233:
4223:
4218:
4213:
4208:
4123:
4067:
4024:
4019:
4014:
4009:
4004:
3999:
3994:
3972:
3967:
3962:
3957:
3952:
3947:
3942:
3923:
3918:
3913:
3908:
3896:
3813:
3808:
3803:
3788:
3726:
3721:
3716:
3707:
3702:
3688:
3683:
3674:
3669:
3664:
3655:
3650:
3641:
3636:
3603:
3598:
3593:
3588:
3579:
3570:
3565:
3560:
3551:
3546:
3541:
3536:
3527:
3522:
3508:
3503:
3498:
3493:
3488:
3483:
3478:
3414:
3409:
3404:
3399:
3394:
3389:
3384:
3379:
3344:
3314:
3309:
3304:
3299:
3270:
3219:
3214:
3209:
3204:
3194:
3189:
3169:
3154:
3149:
3064:
3059:
3054:
3049:
3033:
3013:
2998:
2959:
2954:
2949:
2944:
2852:
2847:
2570:
2565:
2560:
632:
628:
4626:
4621:
4616:
4606:
4601:
4596:
4586:
4581:
4576:
4571:
4566:
4561:
4556:
4541:
4536:
4531:
4526:
4521:
4516:
4455:
4450:
4445:
4440:
4435:
4341:
4329:
4324:
4319:
4250:
4203:
4167:
4162:
4157:
4152:
3879:
3697:
2592:
2582:
2071:
Cha SK, Hu MC, Kurosu H, Kuro-o M, Moe O, Huang CL (July 2009).
1044:
61:
4656:
3841:
3087:
2875:
2532:
2485:
4180:
4078:
3199:
3159:
2114:
Nanazashvili M, Li H, Palmer LG, Walters DE, Sackin H (2007).
1041:
potassium inwardly-rectifying channel, subfamily J, member 1
2116:"Moving the pH gate of the Kir1.1 inward rectifier channel"
1120:
Mutations in this gene have been associated with antenatal
551:
ATP-activated inward rectifier potassium channel activity
317:
2276:"Intersectin links WNK kinases to endocytosis of ROMK1"
482:
1356:"Entrez Gene: potassium inwardly-rectifying channel"
1062:
type potassium channel. It is inhibited by internal
4669:
4493:
4382:
4178:
4076:
4052:
3854:
3460:
3365:
3230:
3103:
2970:
2929:
2891:
2603:
2548:
2319:
1995:"Domains of WNK1 kinase in the regulation of ROMK1"
914:
877:
847:
810:
1524:"Mechanism of hypokalemia in magnesium deficiency"
1171:
1169:
1167:
1150:
1148:
1146:
1086:in the heart as well as in the protection against
264:
163:
2405:American Journal of Physiology. Renal Physiology
2274:He G, Wang HR, Huang SK, Huang CL (April 2007).
1999:American Journal of Physiology. Renal Physiology
1108:-like enzyme that activates ROMK by removal of
1176:GRCm38: Ensembl release 89: ENSMUSG00000041248
2497:
1528:Journal of the American Society of Nephrology
536:phosphatidylinositol-4,5-bisphosphate binding
8:
1128:Role in hypokalemia and magnesium deficiency
1078:) channel, known to play a critical role in
1155:GRCh38: Ensembl release 89: ENSG00000151704
618:potassium ion import across plasma membrane
541:inward rectifier potassium channel activity
4666:
4653:
3851:
3838:
3100:
3084:
2888:
2872:
2545:
2529:
2504:
2490:
2482:
2469:United States National Library of Medicine
2346:Lazrak A, Liu Z, Huang CL (January 2006).
1818:Cho JT, Guay-Woodford LM (February 2003).
643:
508:
305:
204:
101:
2452:at the U.S. National Library of Medicine
2424:
2381:
2371:
2299:
2256:
2246:
2211:
2176:
2166:
2131:
2096:
2053:
2018:
1975:
1965:
1886:
1843:
1763:
1753:
1718:
1644:
1634:
1580:
1539:
1498:
1455:
1445:
1394:
603:regulation of ion transmembrane transport
2467:This article incorporates text from the
1993:Wang HR, Liu Z, Huang CL (August 2008).
1350:
1348:
1346:
1142:
1003:renal outer medullary potassium channel
577:voltage-gated potassium channel complex
1033:. In humans, ROMK is encoded by the
18:
2280:The Journal of Clinical Investigation
2149:Liu Z, Wang HR, Huang CL (May 2009).
1707:Nephrology, Dialysis, Transplantation
1069:mitochondrial ATP-sensitive potassium
269:
230:
225:
168:
127:
122:
7:
3870:Calcium-activated chloride channels
2200:The Journal of Biological Chemistry
2155:The Journal of Biological Chemistry
2042:The Journal of Biological Chemistry
1954:The Journal of Biological Chemistry
1569:The Journal of Biological Chemistry
449:outer stripe of outer renal medulla
437:inner stripe of outer renal medulla
2940:Amiloride-sensitive cation channel
2248:10.1161/HYPERTENSIONAHA.108.112664
911:
874:
844:
807:
783:
764:
738:
719:
693:
674:
531:voltage-gated ion channel activity
487:
405:
343:
322:
14:
2399:Welling PA, Ho K (October 2009).
1824:Journal of Korean Medical Science
1522:Huang CL, Kuo E (October 2007).
253:
246:
240:
217:
152:
145:
139:
114:
4463:Voltage-dependent anion channel
2556:Inositol trisphosphate receptor
1783:Histochemistry and Cell Biology
1736:Lee JR, Shieh RC (March 2009).
4485:General bacterial porin family
567:integral component of membrane
471:More reference expression data
1:
1742:Journal of Biomedical Science
1387:10.1161/circresaha.112.266445
238:
137:
4735:Genes on human chromosome 11
1088:hypoxia-induced brain injury
2417:10.1152/ajprenal.00181.2009
2011:10.1152/ajprenal.90287.2008
1084:ischemic-reperfusion injury
4756:
3904:Chloride Channel Accessory
2513:Membrane transport protein
2331:10.1016/j.bbrc.2008.08.076
943:Chr 11: 128.84 – 128.87 Mb
4710:
4665:
4652:
3850:
3837:
3099:
3083:
2899:Epithelial sodium channel
2887:
2871:
2544:
2528:
1925:10.1007/s00467-007-0468-4
1836:10.3346/jkms.2003.18.1.65
1795:10.1007/s00418-004-0742-5
1211:"Mouse PubMed Reference:"
1193:"Human PubMed Reference:"
988:
983:
979:
972:
956:
937:
918:
881:
870:
851:
814:
803:
790:
786:
771:
767:
758:
745:
741:
726:
722:
713:
700:
696:
681:
677:
668:
653:
646:
642:
626:
511:
507:
495:
490:
481:
468:
417:
408:
355:
346:
316:
308:
304:
287:
274:
237:
216:
207:
203:
186:
173:
136:
113:
104:
100:
55:
52:
42:
35:
30:
26:
21:
2816:Cation channels of sperm
2454:Medical Subject Headings
1027:cortical collecting duct
457:cortical collecting duct
2373:10.1073/pnas.0510609103
1755:10.1186/1423-0127-16-29
1665:Pharmacological Reviews
1636:10.1073/pnas.0504332102
1447:10.1073/pnas.0803223105
1309:Pharmacological Reviews
950:Chr 9: 32.28 – 32.31 Mb
613:potassium ion transport
2213:10.1074/jbc.M311599200
2168:10.1074/jbc.M806551200
2089:10.1124/mol.109.055780
2077:Molecular Pharmacology
2055:10.1074/jbc.M212301200
1967:10.1074/jbc.M705574200
1582:10.1074/jbc.M212301200
1541:10.1681/asn.2007070792
1281:Molecular Pharmacology
1009:) is an ATP-dependent
371:metanephric glomerulus
2892:Constitutively active
1116:Clinical significance
130:Chromosome 11 (human)
2460:NDI terminology page
2450:ROMK1+protein,+human
1913:Pediatric Nephrology
1486:Kidney International
1375:Circulation Research
1021:(TAL) and potassium
1019:thick ascending limb
441:olfactory epithelium
232:Chromosome 9 (mouse)
4659:By gating mechanism
2364:2006PNAS..103.1615L
1627:2005PNAS..102.9954O
1575:(25): 23066–23075.
1438:2008PNAS..105.9805C
1242:1993Natur.362...31H
429:inner renal medulla
387:epithelium of colon
4186:TRP cation channel
4084:CNG cation channel
3367:Tandem pore domain
2578:Ryanodine receptor
2471:, which is in the
1720:10.1093/ndt/gfn689
1677:10.1124/pr.57.4.11
1500:10.1038/ki.2010.73
1321:10.1124/pr.57.4.11
1106:beta-glucuronidase
1056:Potassium channels
748:ENSMUSG00000041248
591:Biological process
560:Cellular component
526:nucleotide binding
519:Molecular function
395:tail of epididymis
4722:
4721:
4706:
4705:
4702:
4701:
4694:Stretch-activated
4671:Ion channel class
4648:
4647:
4644:
4643:
3833:
3832:
3829:
3828:
3105:Calcium-activated
3093:Potassium channel
3079:
3078:
3075:
3074:
2867:
2866:
2863:
2862:
2161:(18): 12198–206.
2133:10.4161/chan.3707
1534:(10): 2649–2652.
1479:Huang CL (2010).
1432:(28): 9805–9810.
1011:potassium channel
999:
998:
995:
994:
968:
967:
933:
932:
908:
907:
866:
865:
841:
840:
799:
798:
780:
779:
754:
753:
735:
734:
709:
708:
690:
689:
638:
637:
503:
502:
499:
498:
477:
476:
464:
463:
453:Convoluted tubule
445:connecting tubule
402:
401:
383:nucleus accumbens
300:
299:
199:
198:
94:KCNJ1 - orthologs
16:Potassium channel
4747:
4667:
4654:
3862:Chloride channel
3852:
3839:
3232:Inward-rectifier
3101:
3085:
2889:
2873:
2843:Two-pore channel
2546:
2530:
2506:
2499:
2492:
2483:
2438:
2428:
2395:
2385:
2375:
2342:
2313:
2303:
2292:10.1172/JCI30087
2270:
2260:
2250:
2225:
2215:
2190:
2180:
2170:
2145:
2135:
2110:
2100:
2067:
2057:
2048:(25): 23066–75.
2032:
2022:
1989:
1979:
1969:
1944:
1910:
1900:
1890:
1857:
1847:
1814:
1777:
1767:
1757:
1732:
1722:
1696:
1658:
1648:
1638:
1595:
1594:
1584:
1560:
1554:
1553:
1543:
1519:
1513:
1512:
1502:
1476:
1470:
1469:
1459:
1449:
1415:
1409:
1408:
1398:
1366:
1360:
1359:
1352:
1341:
1340:
1303:
1297:
1296:
1276:
1270:
1269:
1250:10.1038/362031a0
1225:
1219:
1218:
1207:
1201:
1200:
1189:
1183:
1173:
1162:
1152:
1122:Bartter syndrome
1080:cardioprotection
1060:inward-rectifier
981:
980:
952:
945:
928:
912:
903:
875:
871:RefSeq (protein)
861:
845:
836:
808:
784:
765:
739:
720:
694:
675:
644:
509:
488:
473:
413:
411:Top expressed in
406:
351:
349:Top expressed in
344:
323:
306:
296:
283:
272:
257:
250:
244:
233:
221:
205:
195:
182:
171:
156:
149:
143:
132:
118:
102:
96:
47:
40:
19:
4755:
4754:
4750:
4749:
4748:
4746:
4745:
4744:
4725:
4724:
4723:
4718:
4698:
4661:
4640:
4489:
4388:
4378:
4174:
4072:
4048:
3846:
3825:
3739:
3616:
3473:
3456:
3361:
3325:
3295:
3251:
3243:
3226:
3180:
3095:
3071:
3044:
2983:
2966:
2925:
2883:
2859:
2742:
2714:
2701:
2688:
2668:
2655:
2620:
2599:
2540:
2538:Calcium channel
2524:
2510:
2479:
2465:
2446:
2441:
2398:
2345:
2316:
2273:
2228:
2193:
2148:
2113:
2070:
2035:
1992:
1960:(12): 7674–81.
1947:
1908:
1903:
1867:Nature Genetics
1860:
1817:
1780:
1735:
1699:
1661:
1608:
1604:
1602:Further reading
1599:
1598:
1562:
1561:
1557:
1521:
1520:
1516:
1493:(10): 855–860.
1478:
1477:
1473:
1417:
1416:
1412:
1368:
1367:
1363:
1354:
1353:
1344:
1305:
1304:
1300:
1278:
1277:
1273:
1227:
1226:
1222:
1209:
1208:
1204:
1191:
1190:
1186:
1174:
1165:
1153:
1144:
1139:
1130:
1118:
1076:
1053:
1016:
990:View/Edit Mouse
985:View/Edit Human
948:
941:
938:Location (UCSC)
924:
920:
899:
895:
891:
887:
883:
857:
853:
832:
828:
824:
820:
816:
729:ENSG00000151704
622:
586:
582:plasma membrane
555:
469:
460:
455:
451:
447:
443:
439:
435:
431:
427:
423:
409:
398:
393:
389:
385:
381:
377:
373:
369:
365:
361:
347:
291:
278:
270:
260:
259:
258:
251:
231:
208:Gene location (
190:
177:
169:
159:
158:
157:
150:
128:
105:Gene location (
56:
43:
36:
17:
12:
11:
5:
4753:
4751:
4743:
4742:
4737:
4727:
4726:
4720:
4719:
4711:
4708:
4707:
4704:
4703:
4700:
4699:
4697:
4696:
4691:
4686:
4681:
4675:
4673:
4663:
4662:
4657:
4650:
4649:
4646:
4645:
4642:
4641:
4639:
4638:
4633:
4632:
4631:
4630:
4629:
4624:
4619:
4611:
4610:
4609:
4604:
4599:
4591:
4590:
4589:
4584:
4579:
4574:
4569:
4564:
4559:
4551:
4550:
4549:
4544:
4539:
4534:
4529:
4524:
4519:
4505:
4503:
4491:
4490:
4488:
4487:
4482:
4481:
4480:
4475:
4470:
4460:
4459:
4458:
4453:
4448:
4443:
4438:
4433:
4428:
4423:
4418:
4413:
4402:
4400:
4386:
4380:
4379:
4377:
4376:
4375:
4374:
4369:
4364:
4359:
4354:
4349:
4339:
4338:
4337:
4332:
4322:
4317:
4316:
4315:
4310:
4305:
4295:
4294:
4293:
4288:
4283:
4278:
4273:
4268:
4263:
4258:
4248:
4247:
4246:
4241:
4236:
4231:
4226:
4221:
4216:
4211:
4201:
4190:
4188:
4176:
4175:
4173:
4172:
4171:
4170:
4165:
4160:
4155:
4150:
4138:
4137:
4136:
4131:
4126:
4116:
4115:
4114:
4109:
4104:
4099:
4088:
4086:
4074:
4073:
4071:
4070:
4064:
4062:
4060:Proton channel
4050:
4049:
4047:
4046:
4045:
4044:
4039:
4029:
4028:
4027:
4022:
4017:
4012:
4007:
4002:
3997:
3987:
3986:
3985:
3980:
3975:
3970:
3965:
3960:
3955:
3950:
3945:
3935:
3930:
3929:
3928:
3927:
3926:
3921:
3916:
3911:
3901:
3900:
3899:
3894:
3884:
3883:
3882:
3866:
3864:
3848:
3847:
3842:
3835:
3834:
3831:
3830:
3827:
3826:
3824:
3823:
3818:
3817:
3816:
3811:
3806:
3796:
3791:
3786:
3785:
3784:
3779:
3774:
3769:
3759:
3758:
3757:
3752:
3747:
3737:
3732:
3731:
3730:
3729:
3724:
3719:
3712:
3711:
3710:
3705:
3700:
3693:
3692:
3691:
3686:
3679:
3678:
3677:
3672:
3667:
3660:
3659:
3658:
3653:
3646:
3645:
3644:
3639:
3634:
3629:
3624:
3614:
3609:
3608:
3607:
3606:
3601:
3596:
3591:
3584:
3583:
3582:
3575:
3574:
3573:
3568:
3563:
3556:
3555:
3554:
3549:
3544:
3539:
3532:
3531:
3530:
3525:
3518:
3517:
3516:
3511:
3506:
3501:
3496:
3491:
3486:
3481:
3471:
3466:
3464:
3458:
3457:
3455:
3454:
3453:
3452:
3447:
3442:
3437:
3432:
3427:
3422:
3417:
3412:
3407:
3402:
3397:
3392:
3387:
3382:
3371:
3369:
3363:
3362:
3360:
3359:
3358:
3357:
3352:
3347:
3342:
3337:
3332:
3323:
3319:
3318:
3317:
3312:
3307:
3302:
3293:
3285:
3284:
3283:
3278:
3273:
3268:
3263:
3258:
3249:
3245:
3241:
3236:
3234:
3228:
3227:
3225:
3224:
3223:
3222:
3217:
3212:
3207:
3202:
3197:
3192:
3187:
3178:
3174:
3173:
3172:
3164:
3163:
3162:
3157:
3152:
3142:
3141:
3140:
3135:
3130:
3125:
3120:
3109:
3107:
3097:
3096:
3088:
3081:
3080:
3077:
3076:
3073:
3072:
3070:
3069:
3068:
3067:
3062:
3057:
3052:
3042:
3038:
3037:
3036:
3031:
3026:
3021:
3016:
3011:
3006:
3001:
2996:
2991:
2981:
2976:
2974:
2968:
2967:
2965:
2964:
2963:
2962:
2957:
2952:
2947:
2936:
2934:
2927:
2926:
2924:
2923:
2922:
2921:
2916:
2911:
2906:
2895:
2893:
2885:
2884:
2881:Sodium channel
2876:
2869:
2868:
2865:
2864:
2861:
2860:
2858:
2857:
2856:
2855:
2850:
2840:
2839:
2838:
2833:
2828:
2823:
2812:
2811:
2810:
2809:
2804:
2799:
2794:
2784:
2783:
2782:
2777:
2772:
2767:
2757:
2756:
2755:
2750:
2740:
2735:
2734:
2733:
2732:
2727:
2722:
2712:
2704:
2699:
2691:
2686:
2678:
2677:
2676:
2666:
2658:
2653:
2645:
2644:
2643:
2638:
2633:
2628:
2618:
2609:
2607:
2601:
2600:
2598:
2597:
2596:
2595:
2590:
2585:
2575:
2574:
2573:
2568:
2563:
2552:
2550:
2542:
2541:
2533:
2526:
2525:
2511:
2509:
2508:
2501:
2494:
2486:
2463:
2462:
2457:
2445:
2444:External links
2442:
2440:
2439:
2411:(4): F849–63.
2396:
2358:(5): 1615–20.
2343:
2314:
2286:(4): 1078–87.
2271:
2241:(6): 1658–64.
2226:
2206:(8): 6863–73.
2191:
2146:
2111:
2068:
2033:
2005:(2): F438–45.
1990:
1945:
1919:(8): 1219–23.
1901:
1879:10.1038/ng.118
1873:(5): 592–599.
1858:
1815:
1778:
1733:
1713:(5): 1455–64.
1697:
1659:
1621:(28): 9954–9.
1605:
1603:
1600:
1597:
1596:
1555:
1514:
1471:
1410:
1361:
1342:
1298:
1271:
1236:(6415): 31–8.
1220:
1202:
1184:
1163:
1141:
1140:
1138:
1135:
1129:
1126:
1117:
1114:
1074:
1052:
1049:
1014:
997:
996:
993:
992:
987:
977:
976:
970:
969:
966:
965:
963:
961:
954:
953:
946:
939:
935:
934:
931:
930:
916:
915:
909:
906:
905:
879:
878:
872:
868:
867:
864:
863:
849:
848:
842:
839:
838:
812:
811:
805:
801:
800:
797:
796:
788:
787:
781:
778:
777:
769:
768:
762:
756:
755:
752:
751:
743:
742:
736:
733:
732:
724:
723:
717:
711:
710:
707:
706:
698:
697:
691:
688:
687:
679:
678:
672:
666:
665:
660:
655:
651:
650:
640:
639:
636:
635:
624:
623:
621:
620:
615:
610:
605:
600:
594:
592:
588:
587:
585:
584:
579:
574:
569:
563:
561:
557:
556:
554:
553:
548:
543:
538:
533:
528:
522:
520:
516:
515:
505:
504:
501:
500:
497:
496:
493:
492:
485:
479:
478:
475:
474:
466:
465:
462:
461:
459:
458:
454:
450:
446:
442:
438:
434:
430:
426:
422:
418:
415:
414:
403:
400:
399:
397:
396:
392:
388:
384:
380:
376:
372:
368:
364:
360:
356:
353:
352:
340:
339:
331:
320:
314:
313:
310:RNA expression
302:
301:
298:
297:
289:
285:
284:
276:
273:
268:
262:
261:
252:
245:
239:
235:
234:
229:
223:
222:
214:
213:
201:
200:
197:
196:
188:
184:
183:
175:
172:
167:
161:
160:
151:
144:
138:
134:
133:
126:
120:
119:
111:
110:
98:
97:
54:
50:
49:
41:
33:
32:
28:
27:
24:
23:
15:
13:
10:
9:
6:
4:
3:
2:
4752:
4741:
4738:
4736:
4733:
4732:
4730:
4717:
4716:
4709:
4695:
4692:
4690:
4689:Voltage-gated
4687:
4685:
4682:
4680:
4677:
4676:
4674:
4672:
4668:
4664:
4660:
4655:
4651:
4637:
4634:
4628:
4625:
4623:
4620:
4618:
4615:
4614:
4612:
4608:
4605:
4603:
4600:
4598:
4595:
4594:
4592:
4588:
4585:
4583:
4580:
4578:
4575:
4573:
4570:
4568:
4565:
4563:
4560:
4558:
4555:
4554:
4552:
4548:
4545:
4543:
4540:
4538:
4535:
4533:
4530:
4528:
4525:
4523:
4520:
4518:
4515:
4514:
4512:
4511:
4510:
4507:
4506:
4504:
4502:
4499:
4497:
4492:
4486:
4483:
4479:
4476:
4474:
4471:
4469:
4466:
4465:
4464:
4461:
4457:
4454:
4452:
4449:
4447:
4444:
4442:
4439:
4437:
4434:
4432:
4429:
4427:
4424:
4422:
4419:
4417:
4414:
4412:
4409:
4408:
4407:
4404:
4403:
4401:
4399:
4396:
4394:
4390:
4381:
4373:
4370:
4368:
4365:
4363:
4360:
4358:
4355:
4353:
4350:
4348:
4345:
4344:
4343:
4340:
4336:
4333:
4331:
4328:
4327:
4326:
4323:
4321:
4318:
4314:
4311:
4309:
4306:
4304:
4301:
4300:
4299:
4296:
4292:
4289:
4287:
4284:
4282:
4279:
4277:
4274:
4272:
4269:
4267:
4264:
4262:
4259:
4257:
4254:
4253:
4252:
4249:
4245:
4242:
4240:
4237:
4235:
4232:
4230:
4227:
4225:
4222:
4220:
4217:
4215:
4212:
4210:
4207:
4206:
4205:
4202:
4199:
4195:
4192:
4191:
4189:
4187:
4184:
4182:
4177:
4169:
4166:
4164:
4161:
4159:
4156:
4154:
4151:
4149:
4146:
4145:
4144:
4143:
4139:
4135:
4132:
4130:
4127:
4125:
4122:
4121:
4120:
4117:
4113:
4110:
4108:
4105:
4103:
4100:
4098:
4095:
4094:
4093:
4090:
4089:
4087:
4085:
4082:
4080:
4075:
4069:
4066:
4065:
4063:
4061:
4058:
4056:
4051:
4043:
4040:
4038:
4035:
4034:
4033:
4030:
4026:
4023:
4021:
4018:
4016:
4013:
4011:
4008:
4006:
4003:
4001:
3998:
3996:
3993:
3992:
3991:
3988:
3984:
3981:
3979:
3976:
3974:
3971:
3969:
3966:
3964:
3961:
3959:
3956:
3954:
3951:
3949:
3946:
3944:
3941:
3940:
3939:
3936:
3934:
3931:
3925:
3922:
3920:
3917:
3915:
3912:
3910:
3907:
3906:
3905:
3902:
3898:
3895:
3893:
3890:
3889:
3888:
3885:
3881:
3878:
3877:
3876:
3873:
3872:
3871:
3868:
3867:
3865:
3863:
3860:
3858:
3853:
3849:
3845:
3844:Miscellaneous
3840:
3836:
3822:
3821:Shaker (gene)
3819:
3815:
3812:
3810:
3807:
3805:
3802:
3801:
3800:
3797:
3795:
3794:minK/ISK-like
3792:
3790:
3787:
3783:
3780:
3778:
3775:
3773:
3770:
3768:
3765:
3764:
3763:
3760:
3756:
3753:
3751:
3748:
3746:
3743:
3742:
3741:
3734:
3733:
3728:
3725:
3723:
3720:
3718:
3715:
3714:
3713:
3709:
3706:
3704:
3701:
3699:
3696:
3695:
3694:
3690:
3687:
3685:
3682:
3681:
3680:
3676:
3673:
3671:
3668:
3666:
3663:
3662:
3661:
3657:
3654:
3652:
3649:
3648:
3647:
3643:
3640:
3638:
3635:
3633:
3630:
3628:
3625:
3623:
3620:
3619:
3618:
3611:
3610:
3605:
3602:
3600:
3597:
3595:
3592:
3590:
3587:
3586:
3585:
3581:
3578:
3577:
3576:
3572:
3569:
3567:
3564:
3562:
3559:
3558:
3557:
3553:
3550:
3548:
3545:
3543:
3540:
3538:
3535:
3534:
3533:
3529:
3526:
3524:
3521:
3520:
3519:
3515:
3512:
3510:
3507:
3505:
3502:
3500:
3497:
3495:
3492:
3490:
3487:
3485:
3482:
3480:
3477:
3476:
3475:
3468:
3467:
3465:
3463:
3462:Voltage-gated
3459:
3451:
3448:
3446:
3443:
3441:
3438:
3436:
3433:
3431:
3428:
3426:
3423:
3421:
3418:
3416:
3413:
3411:
3408:
3406:
3403:
3401:
3398:
3396:
3393:
3391:
3388:
3386:
3383:
3381:
3378:
3377:
3376:
3373:
3372:
3370:
3368:
3364:
3356:
3353:
3351:
3348:
3346:
3343:
3341:
3338:
3336:
3333:
3331:
3328:
3327:
3326:
3320:
3316:
3313:
3311:
3308:
3306:
3303:
3301:
3298:
3297:
3296:
3289:
3286:
3282:
3279:
3277:
3274:
3272:
3269:
3267:
3264:
3262:
3259:
3257:
3254:
3253:
3252:
3246:
3244:
3238:
3237:
3235:
3233:
3229:
3221:
3218:
3216:
3213:
3211:
3208:
3206:
3203:
3201:
3198:
3196:
3193:
3191:
3188:
3186:
3183:
3182:
3181:
3175:
3171:
3168:
3167:
3165:
3161:
3158:
3156:
3153:
3151:
3148:
3147:
3146:
3143:
3139:
3136:
3134:
3131:
3129:
3126:
3124:
3121:
3119:
3116:
3115:
3114:
3111:
3110:
3108:
3106:
3102:
3098:
3094:
3091:
3086:
3082:
3066:
3063:
3061:
3058:
3056:
3053:
3051:
3048:
3047:
3046:
3039:
3035:
3032:
3030:
3027:
3025:
3022:
3020:
3017:
3015:
3012:
3010:
3007:
3005:
3002:
3000:
2997:
2995:
2992:
2990:
2987:
2986:
2985:
2978:
2977:
2975:
2973:
2972:Voltage-gated
2969:
2961:
2958:
2956:
2953:
2951:
2948:
2946:
2943:
2942:
2941:
2938:
2937:
2935:
2932:
2928:
2920:
2917:
2915:
2912:
2910:
2907:
2905:
2902:
2901:
2900:
2897:
2896:
2894:
2890:
2886:
2882:
2879:
2874:
2870:
2854:
2851:
2849:
2846:
2845:
2844:
2841:
2837:
2834:
2832:
2829:
2827:
2824:
2822:
2819:
2818:
2817:
2814:
2813:
2808:
2805:
2803:
2800:
2798:
2795:
2793:
2790:
2789:
2788:
2785:
2781:
2778:
2776:
2773:
2771:
2768:
2766:
2763:
2762:
2761:
2758:
2754:
2751:
2749:
2746:
2745:
2744:
2737:
2736:
2731:
2728:
2726:
2723:
2721:
2718:
2717:
2716:
2708:
2705:
2703:
2695:
2692:
2690:
2682:
2679:
2675:
2672:
2671:
2670:
2662:
2659:
2657:
2649:
2646:
2642:
2639:
2637:
2634:
2632:
2629:
2627:
2624:
2623:
2622:
2614:
2611:
2610:
2608:
2606:
2605:Voltage-gated
2602:
2594:
2591:
2589:
2586:
2584:
2581:
2580:
2579:
2576:
2572:
2569:
2567:
2564:
2562:
2559:
2558:
2557:
2554:
2553:
2551:
2547:
2543:
2539:
2536:
2531:
2527:
2522:
2518:
2514:
2507:
2502:
2500:
2495:
2493:
2488:
2487:
2484:
2480:
2477:
2476:
2474:
2473:public domain
2470:
2461:
2458:
2455:
2451:
2448:
2447:
2443:
2436:
2432:
2427:
2422:
2418:
2414:
2410:
2406:
2402:
2397:
2393:
2389:
2384:
2379:
2374:
2369:
2365:
2361:
2357:
2353:
2349:
2344:
2340:
2336:
2332:
2328:
2324:
2320:
2315:
2311:
2307:
2302:
2297:
2293:
2289:
2285:
2281:
2277:
2272:
2268:
2264:
2259:
2254:
2249:
2244:
2240:
2236:
2232:
2227:
2223:
2219:
2214:
2209:
2205:
2201:
2197:
2192:
2188:
2184:
2179:
2174:
2169:
2164:
2160:
2156:
2152:
2147:
2143:
2139:
2134:
2129:
2125:
2121:
2117:
2112:
2108:
2104:
2099:
2094:
2090:
2086:
2082:
2078:
2074:
2069:
2065:
2061:
2056:
2051:
2047:
2043:
2039:
2034:
2030:
2026:
2021:
2016:
2012:
2008:
2004:
2000:
1996:
1991:
1987:
1983:
1978:
1973:
1968:
1963:
1959:
1955:
1951:
1946:
1942:
1938:
1934:
1930:
1926:
1922:
1918:
1914:
1907:
1902:
1898:
1894:
1889:
1884:
1880:
1876:
1872:
1868:
1864:
1859:
1855:
1851:
1846:
1841:
1837:
1833:
1829:
1825:
1821:
1816:
1812:
1808:
1804:
1800:
1796:
1792:
1788:
1784:
1779:
1775:
1771:
1766:
1761:
1756:
1751:
1747:
1743:
1739:
1734:
1730:
1726:
1721:
1716:
1712:
1708:
1704:
1698:
1694:
1690:
1686:
1682:
1678:
1674:
1671:(4): 509–26.
1670:
1666:
1660:
1656:
1652:
1647:
1642:
1637:
1632:
1628:
1624:
1620:
1616:
1612:
1607:
1606:
1601:
1592:
1588:
1583:
1578:
1574:
1570:
1566:
1559:
1556:
1551:
1547:
1542:
1537:
1533:
1529:
1525:
1518:
1515:
1510:
1506:
1501:
1496:
1492:
1488:
1487:
1482:
1475:
1472:
1467:
1463:
1458:
1453:
1448:
1443:
1439:
1435:
1431:
1427:
1426:
1421:
1414:
1411:
1406:
1402:
1397:
1392:
1388:
1384:
1381:(4): 446–54.
1380:
1376:
1372:
1365:
1362:
1357:
1351:
1349:
1347:
1343:
1338:
1334:
1330:
1326:
1322:
1318:
1315:(4): 509–26.
1314:
1310:
1302:
1299:
1294:
1290:
1287:(5): 854–60.
1286:
1282:
1275:
1272:
1267:
1263:
1259:
1255:
1251:
1247:
1243:
1239:
1235:
1231:
1224:
1221:
1216:
1212:
1206:
1203:
1198:
1194:
1188:
1185:
1181:
1177:
1172:
1170:
1168:
1164:
1160:
1156:
1151:
1149:
1147:
1143:
1136:
1134:
1127:
1125:
1123:
1115:
1113:
1111:
1107:
1103:
1099:
1097:
1093:
1089:
1085:
1081:
1077:
1070:
1065:
1061:
1057:
1050:
1048:
1046:
1042:
1038:
1037:
1032:
1029:(CCD) of the
1028:
1024:
1020:
1012:
1008:
1004:
991:
986:
982:
978:
975:
971:
964:
962:
959:
955:
951:
947:
944:
940:
936:
929:
927:
923:
917:
913:
910:
904:
902:
898:
894:
890:
886:
880:
876:
873:
869:
862:
860:
856:
850:
846:
843:
837:
835:
831:
827:
823:
819:
813:
809:
806:
804:RefSeq (mRNA)
802:
795:
794:
789:
785:
782:
776:
775:
770:
766:
763:
761:
757:
750:
749:
744:
740:
737:
731:
730:
725:
721:
718:
716:
712:
705:
704:
699:
695:
692:
686:
685:
680:
676:
673:
671:
667:
664:
661:
659:
656:
652:
649:
645:
641:
634:
630:
625:
619:
616:
614:
611:
609:
608:ion transport
606:
604:
601:
599:
596:
595:
593:
590:
589:
583:
580:
578:
575:
573:
570:
568:
565:
564:
562:
559:
558:
552:
549:
547:
544:
542:
539:
537:
534:
532:
529:
527:
524:
523:
521:
518:
517:
514:
513:Gene ontology
510:
506:
494:
489:
486:
484:
480:
472:
467:
456:
452:
448:
444:
440:
436:
433:distal tubule
432:
428:
424:
420:
419:
416:
412:
407:
404:
394:
390:
386:
382:
378:
374:
370:
366:
363:kidney tubule
362:
359:renal medulla
358:
357:
354:
350:
345:
342:
341:
338:
336:
332:
330:
329:
325:
324:
321:
319:
315:
311:
307:
303:
295:
290:
286:
282:
277:
267:
263:
256:
249:
243:
236:
228:
224:
220:
215:
211:
206:
202:
194:
189:
185:
181:
176:
166:
162:
155:
148:
142:
135:
131:
125:
121:
117:
112:
108:
103:
99:
95:
91:
87:
83:
79:
75:
71:
67:
63:
59:
51:
46:
39:
34:
29:
25:
20:
4740:Ion channels
4712:
4679:Ligand-gated
4670:
4658:
4501:Gap junction
4494:
4383:
4179:
4140:
4118:
4091:
4077:
4053:
4031:
3989:
3937:
3903:
3886:
3874:
3855:
3843:
3798:
3761:
3735:
3612:
3469:
3374:
3321:
3291:
3255:
3247:
3176:
3089:
3040:
2979:
2877:
2786:
2759:
2738:
2710:
2697:
2684:
2664:
2651:
2616:
2549:Ligand-gated
2534:
2517:ion channels
2478:
2466:
2464:
2408:
2404:
2355:
2351:
2325:(4): 651–4.
2322:
2318:
2283:
2279:
2238:
2235:Hypertension
2234:
2203:
2199:
2158:
2154:
2123:
2119:
2083:(1): 38–46.
2080:
2076:
2045:
2041:
2002:
1998:
1957:
1953:
1916:
1912:
1870:
1866:
1827:
1823:
1789:(6): 553–9.
1786:
1782:
1745:
1741:
1710:
1706:
1668:
1664:
1618:
1614:
1572:
1568:
1558:
1531:
1527:
1517:
1490:
1484:
1474:
1429:
1423:
1413:
1378:
1374:
1364:
1312:
1308:
1301:
1284:
1280:
1274:
1233:
1229:
1223:
1214:
1205:
1196:
1187:
1131:
1119:
1100:
1054:
1040:
1035:
1034:
1006:
1002:
1000:
922:NP_001161826
919:
882:
855:NM_001168354
852:
815:
791:
772:
746:
727:
701:
682:
662:
657:
425:human kidney
421:right kidney
375:human kidney
333:
326:
191:128,867,373
178:128,836,315
53:External IDs
4684:Light-gated
3166:IK channel
2126:(1): 21–8.
1830:(1): 65–8.
1110:sialic acid
546:ATP binding
292:32,310,493
279:32,283,789
271:9|9 A4
31:Identifiers
4729:Categories
3887:Bestrophin
3145:SK channel
3113:BK channel
2787:γ-subunits
2760:β-subunits
2743:δ-subunits
1977:2066/70313
1182:, May 2017
1161:, May 2017
1137:References
367:glomerulus
337:(ortholog)
74:HomoloGene
4715:disorders
4713:see also
4496:Cytoplasm
4406:Aquaporin
3875:Anoctamin
3698:11.1/hERG
2258:2381/4837
1748:(1): 29.
1098:attacks.
1094:or other
1023:secretion
926:NP_062633
901:NP_722451
897:NP_722450
893:NP_722449
889:NP_722448
885:NP_000211
859:NM_019659
834:NM_153766
830:NM_153765
826:NM_153764
822:NM_000220
818:NM_153767
648:Orthologs
598:excretion
82:GeneCards
4509:Connexin
3789:minK/ISK
2435:19458126
2392:16428287
2339:18755144
2310:17380208
2267:18443236
2222:14604981
2187:19244242
2142:19170254
2120:Channels
2107:19349416
2064:12684516
2029:18550644
1986:18211905
1941:36736809
1933:17401586
1897:18391953
1854:12589089
1811:24421285
1803:15895241
1774:19272129
1729:19096086
1693:11588492
1685:16382105
1655:15987778
1591:12684516
1550:17804670
1509:20375979
1466:18606998
1405:22811560
1337:11588492
1329:16382105
1178:–
1157:–
1096:ischemic
1082:against
1051:Function
974:Wikidata
627:Sources:
572:membrane
379:testicle
4636:Innexin
4393:solutes
2426:2775575
2383:1360592
2360:Bibcode
2301:1821066
2178:2673288
2098:2701452
2020:2519181
1888:3766631
1845:3055000
1765:2672938
1646:1175014
1623:Bibcode
1457:2474477
1434:Bibcode
1396:3560389
1293:8190102
1266:4332298
1258:7680431
1238:Bibcode
1180:Ensembl
1159:Ensembl
1031:nephron
1025:in the
760:UniProt
715:Ensembl
654:Species
633:QuickGO
391:putamen
312:pattern
170:11q24.3
70:1927248
38:Aliases
2933:-gated
2931:Proton
2707:T-type
2694:R-type
2681:Q-type
2661:P-type
2648:N-type
2613:L-type
2456:(MeSH)
2433:
2423:
2390:
2380:
2337:
2308:
2298:
2265:
2220:
2185:
2175:
2140:
2105:
2095:
2062:
2027:
2017:
1984:
1939:
1931:
1895:
1885:
1852:
1842:
1809:
1801:
1772:
1762:
1727:
1691:
1683:
1653:
1643:
1589:
1548:
1507:
1464:
1454:
1403:
1393:
1335:
1327:
1291:
1264:
1256:
1230:Nature
1102:Klotho
1092:stroke
960:search
958:PubMed
793:O88335
774:P48048
670:Entrez
483:BioGPS
62:600359
4547:GJA10
4398:Porin
4298:TRPML
4068:HVCN1
3762:KCNIP
3617:α7-12
2521:TC 1A
1937:S2CID
1909:(PDF)
1807:S2CID
1689:S2CID
1333:S2CID
1262:S2CID
1104:is a
1090:from
1073:mitoK
1036:KCNJ1
703:56379
663:Mouse
658:Human
629:Amigo
335:Mouse
328:Human
275:Start
210:Mouse
174:Start
107:Human
86:KCNJ1
78:56764
45:KCNJ1
22:KCNJ1
4627:GJD4
4622:GJD3
4617:GJD2
4607:GJC3
4602:GJC2
4597:GJC1
4587:GJB7
4582:GJB6
4577:GJB5
4572:GJB4
4567:GJB3
4562:GJB2
4557:GJB1
4542:GJA9
4537:GJA8
4532:GJA5
4527:GJA4
4522:GJA3
4517:GJA1
4342:TRPV
4325:TRPP
4320:TRPN
4251:TRPM
4204:TRPC
4194:TRPA
4032:CLNS
3990:CLIC
3938:CLCN
3933:CFTR
3880:ANO1
3799:MiRP
3727:12.3
3722:12.2
3717:12.1
3708:11.3
3703:11.2
3689:10.2
3684:10.1
3474:α1-6
3288:GIRK
2702:α2.3
2689:α2.1
2656:α2.2
2431:PMID
2388:PMID
2335:PMID
2306:PMID
2263:PMID
2218:PMID
2183:PMID
2138:PMID
2103:PMID
2060:PMID
2025:PMID
1982:PMID
1929:PMID
1893:PMID
1850:PMID
1799:PMID
1770:PMID
1725:PMID
1681:PMID
1651:PMID
1587:PMID
1546:PMID
1505:PMID
1462:PMID
1401:PMID
1325:PMID
1289:PMID
1254:PMID
1045:gene
1007:ROMK
1001:The
684:3758
318:Bgee
266:Band
227:Chr.
165:Band
124:Chr.
58:OMIM
4391:(+
4229:4AP
4142:HCN
3675:9.3
3670:9.2
3665:9.1
3656:8.2
3651:8.1
3642:7.5
3637:7.4
3632:7.3
3627:7.2
3622:7.1
3604:6.4
3599:6.3
3594:6.2
3589:6.1
3580:5.1
3571:4.3
3566:4.2
3561:4.1
3552:3.4
3547:3.3
3542:3.2
3537:3.1
3528:2.2
3523:2.1
3514:1.8
3509:1.7
3504:1.6
3499:1.5
3494:1.4
3489:1.3
3484:1.2
3479:1.1
3375:K2P
3355:7.1
3350:6.2
3345:6.1
3340:5.1
3335:4.2
3330:4.1
3315:3.4
3310:3.3
3305:3.2
3300:3.1
3281:2.6
3276:2.4
3271:2.3
3266:2.2
3261:2.1
3256:1.1
3242:ATP
3220:5.1
3215:4.2
3210:4.1
3205:3.1
3200:2.3
3195:2.2
3190:2.1
3185:1.1
3170:IK1
3160:SK3
3155:SK2
3150:SK1
3029:1.9
3024:1.8
3019:1.7
3014:1.6
3009:1.5
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