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354:) or computers preloaded with the same control game plus Re-Mission. Study results indicated that playing Re-Mission led to more consistent treatment adherence, faster rate of increase in cancer knowledge, and faster rate of increase in self-efficacy in young cancer patients. These findings were published in August 2008 in the
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constitute a component of a broader integrative approach to healthcare that synergistically combines rationally targeted biological and behavioral interventions to aid patients in the prevention, detection, treatment, and recovery from disease. HopeLab conducted additional research to understand the
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is designed to improve psychological and behavioral outcomes associated with cancer treatment adherence. Each game puts players inside the body to fight cancer with weapons like chemotherapy, antibiotics and the body's natural defenses. Game play parallels real-world strategies used to fight cancer
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questionnaires, and electronic pill-cap monitors were used to determine utilization of prescribed antibiotics. Researchers concluded that a carefully designed video game can have a positive impact on health behavior in young people with chronic illness and that video-game–based interventions may
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published in 2012 by HopeLab and
Stanford University researchers, showing that the Re-Mission video game strongly activates brain circuits involved in positive motivation. This reward-related activation is associated with a shift in attitudes and emotions that helped boost players’ adherence to
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game puts players inside the body to defeat cancer, using weapons like chemotherapy, antibiotics and the body's immune cells. The games are designed specifically for teens and young adults who are at risk of adverse cancer outcomes due to poor treatment adherence. Research on
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had been distributed in 81 countries, placing it among the most successful serious games to date. HopeLab engaged organizations and individuals worldwide to facilitate distribution of the game to teens and young adults with cancer. On May 30, 2007,
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is designed to inform the patient on a variety of treatments, how they function, and the importance of maintaining strict adherence to those treatments. Various "weapons" are used, such as the
Chemoblaster, Radiation Gun, and antibiotic rocket.
178:, among others. The games engage young cancer patients through entertaining game play while impacting specific psychological and behavioral outcomes associated with successful cancer treatment. HopeLab has made
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showing the impact of the game on neurological processes were presented in August 2008 at the 10th
International Congress of the Society of Behavioral Medicine. This research informed HopeLab's development of
350:. The study enrolled 375 cancer patients aged 13–29 at 34 medical centers in the United States, Canada and Australia. Subjects received either computers pre-loaded with a popular commercial video game (the
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devices. The browser-based games and mobile app offer a variety of game play styles for young cancer patients who spend time online and on mobile devices.
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games available at no charge to young people with cancer and their families, as well as oncology healthcare workers and institutions around the world.
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level. The player must also monitor patient health and report any symptoms back to Dr. West (the in-game doctor and project leader). Each of the 20
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HopeLab conducted an international, multicenter randomized controlled trial to gauge the efficacy of Re-Mission as it relates to
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who is designed to be injected into the human body and fight particular types of cancer and related infections such as
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game in increasing players’ self-efficacy, boosting positive emotions and shifting attitudes about chemotherapy.
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were distributed at no charge to others, though donations were accepted. As of 2012, more than 200,000 copies of
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game is designed to boost positive emotion, increase self-efficacy, and shift attitudes toward chemotherapy.
38:
723:
619:"A Video Game Improves Behavioral Outcomes in Adolescents and Young Adults With Cancer: A Randomized Trial"
559:"A Video Game Improves Behavioral Outcomes in Adolescents and Young Adults With Cancer: A Randomized Trial"
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and win. More than 120 young people with cancer participated in the research and development of the games.
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games for young cancer patients were conceived by Pam
Omidyar and designed based research by the nonprofit
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156:
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A Video Game
Improves Behavioral Outcomes in Adolescents and Young Adults With Cancer: A Randomized Trial
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to measure levels of prescribed chemotherapy in the bodies of study participants rather than subjective
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to its members at no cost. HopeLab has also partnered with
Starlight Children's Foundation and the
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prescribed chemotherapy and antibiotic treatments in a previous study. As a result, each
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500:"Interactivity and Reward-Related Neural Activation during a Serious Videogame"
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Kato, Pamela M.; Cole, Steve W.; Bradlyn, Andrew S.; Pollock, Brad H. (2008).
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the 2013 follow-up to the original game. A collection of free online games,
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announced a partnership with HopeLab in which Cigna distributes copies of
633:"HopeLab website, Our Research: Re-Mission™ Attitudes Study in the Brain"
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364:. Notably, to ascertain treatment compliance, researches used objective
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Winners
Announced in HopeLab’s Global Competition to Get Kids Moving!
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Using a Mobile App to Fight Cancer, HUFFPOST Live, November 5, 2013
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Silicon Valley
Nonprofit in Spotlight After Trip to White House
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436:"Cigna HealthCare Teams with HopeLab to Help Blast Teen Cancer"
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712:" by Christopher Lee, The Washington Post (October 21, 2006)
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Games for Health
Keynote Speaker Steve W. Cole on ReMission
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HopeLab's
Playful Approach to Overcoming Childhood Obesity
605:"HopeLab website, Our Research: Re-Mission Outcomes Study"
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shows that the new games are as effective as the original
808:
F as in Fat: How Obesity Policies are Failing in America
705:" by Erin Hoffman, Serious Games Source (November, 2006)
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Cole, Steven W.; Yoo, Daniel J.; Knutson, Brian (2012).
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main site supporting game orders and online community
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Study Shows Video Games Can Change Behavior, Biology
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Re-Mission: game sequel lets you blast cancer cells
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710:Video Games Aim to Hook Children on Better Health
759:Video Game Helps Young Cancer Patients Take Meds
647:"International Society of Behavioral Medicine"
766:Startup Uses Video Games to Heal Young People
8:
773:Video Game Helps Kids Blast at Their Cancer
724:HopeLab: Providing Help Through Video Games
851:Video games developed in the United States
810:" Trust for America's Health (August 2007)
768:" San Francisco Chronicle (August 4, 2008)
733:," The Huffington Post Blog (May 20, 2013)
731:Learning to Game Your Way to Better Health
726:," Gaming Illustrated (September 30, 2013)
485:"New Cancer-Fighting Game App Goes Global"
412:"Video Game Benefits Children With Cancer"
346:treatments, cancer-related knowledge, and
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815:2005-2006 President's Cancer Panel report
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212:, the player controls an RX5-E ("Roxxi")
794:OMG! Denver Girls Txt It! Game Is Winner
685:Ruckus Nation idea competition main site
49:of all important aspects of the article.
747:" San Jose Mercury News (July 15, 2009)
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471:"HopeLab website, Re-Mission research"
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45:Please consider expanding the lead to
752:A Video Game Helping Kids With Cancer
680:main site supporting online game play
257:Foundation to distribute Re-Mission.
7:
14:
740:" Smart Planet (October 30, 2009)
719:," USA Today (September 19, 2013)
310:games are free to play online at
803:" Press Release (March 17, 2008)
782:" Press Release (August 4, 2008)
23:
775:" Toronto Star (August 4, 2008)
318:is available for download as a
316:Re-Mission 2: Nanobot’s Revenge
196:game was released in 2006 as a
37:may be too short to adequately
796:" Denver Post (March 30, 2008)
754:" CTV Toronto (August 7, 2008)
47:provide an accessible overview
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525:10.1371/journal.pone.0033909
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789:" Pediatrics (August 2008)
761:" Reuters (August 5, 2008)
381:effective. Results of an
866:Realtime Associates games
95:Realtime Associates, Inc.
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281:applies insights from a
836:Educational video games
575:10.1542/peds.2007-3134
451:Cite journal requires
846:Third-person shooters
416:www.gamedeveloper.com
139:Third-person shooters
375:mechanisms of action
218:non-Hodgkin lymphoma
202:third-person shooter
871:Medical video games
691:Articles and videos
516:2012PLoSO...733909C
283:brain-imaging study
176:Realtime Associates
861:Windows-only games
320:mobile app for iOS
172:HopeLab Foundation
664:HopeLab main site
198:Microsoft Windows
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102:Publisher(s)
90:Developer(s)
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34:lead section
370:self-report
366:blood tests
157:multiplayer
114:Platform(s)
825:Categories
670:Re-Mission
563:Pediatrics
421:2024-01-09
398:References
387:Re-Mission
379:Re-Mission
377:that make
361:Pediatrics
344:antibiotic
336:compliance
304:Re-Mission
251:Re-Mission
242:Re-Mission
238:Re-Mission
236:Copies of
210:Re-Mission
208:genre. In
194:Re-Mission
187:Re-Mission
180:Re-Mission
167:Re-Mission
72:Re-Mission
385:study of
83:Cover art
39:summarize
841:Oncology
591:11690124
583:18676516
544:22442733
504:PLOS ONE
330:Research
226:cellular
222:leukemia
134:Genre(s)
535:3307771
512:Bibcode
324:Android
224:, at a
214:nanobot
149:Mode(s)
125:Release
119:Windows
107:HopeLab
589:
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314:, and
230:levels
200:based
587:S2CID
293:Each
579:PMID
540:PMID
457:help
383:fMRI
342:and
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520:doi
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Text is available under the Creative Commons Attribution-ShareAlike License. Additional terms may apply.
