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from a randomized, controlled study conducted by
Hopelab, with support from the Robert Wood Johnson Foundation, showed that middle-school children using Zamzee boosted their physical activity levels by 59% compared to a control group. The study also showed significant increases in physical activity for at-risk groups, including a 103% increase among girls and 27% increase among overweight participants. Other outcomes included positive impacts on LDL cholesterol and glycated hemoglobin, key biomarkers for heart disease and type 2 diabetes. These results were announced at the 2012 Obesity Society annual meeting in San Antonio, Texas.
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412:) or computers preloaded with the same control game plus Re-Mission. Study results indicated that playing Re-Mission led to more consistent treatment adherence, faster rate of increase in cancer knowledge, and faster rate of increase in self-efficacy in young cancer patients. These findings were published in August 2008 in the
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awarded to winners across four competition categories. More than 1,142 people registered to compete, and 429 ideas were submitted by teams representing 37 countries and 41 U.S. states. Contestants ranged in age from 6 to 82 years of age. Semifinalist teams were announced March 10, 2008. On March 17,
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Zamzee is a game-based product prototyped and tested by
Hopelab as a tool to motivate children, families and groups to be more physically active. The product combines an activity tracker that records physical activity and a motivational website where activity is rewarded with points and prizes. Data
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Re-Mission 2 applies insights from a brain-imaging study published in 2012 by
Hopelab and Stanford University researchers, showing that the Re-Mission video game strongly activates brain circuits involved in positive motivation. This reward-related activation is associated with a shift in attitudes
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As of June 2013, more than 202,000 copies of Re-Mission have been distributed in 81 countries, placing it among the most successful serious games to date. Hopelab engages organizations and individuals worldwide to facilitate distribution of the game to teens and young adults with cancer. On May 30,
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Hopelab makes Re-Mission available at no charge to young people with cancer and their families, as well as oncology healthcare workers and institutions around the world. Copies are also distributed at no charge to others, though donations are accepted. The game is available in
English, Spanish, and
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In 2010 Hopelab launched Zamzee Co., a for-profit enterprise with a social mission to get kids and families moving more. Hopelab provided seed funding to the enterprise by way of a program-related equity investment of $ 1 million. Zamzee Co.’s objective was to market and conduct ongoing development
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Re-Mission 2 games are free to play online at re-mission2.org, and Re-Mission 2: Nanobot's
Revenge is available for download as a mobile app for iOS and Android devices. The browser-based games and mobile app offer a variety of gameplay styles for young cancer patients who spend time online and on
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Re-Mission 2, a collection of free online games, is the follow-up to
Hopelab's Re-Mission video game, released in 2006. Re-Mission 2 is designed to improve psychological and behavioral outcomes associated with cancer treatment adherence. Each game puts players inside the body to fight cancer with
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questionnaires, and electronic pill-cap monitors were used to determine utilization of prescribed antibiotics. Researchers concluded that a carefully designed video game can have a positive impact on health behavior in young people with chronic illness and that video-game–based interventions may
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The games are designed specifically for teens and young adults who are at risk of adverse cancer outcomes due to poor treatment adherence. Research on Re-Mission 2 shows that the new games are as effective as the original Re-Mission game in increasing players’ self-efficacy, boosting positive
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and emotions that helped boost players’ adherence to prescribed chemotherapy and antibiotic treatments in a previous study. As a result, each Re-Mission 2 game is designed to boost positive emotion, increase self-efficacy, and shift attitudes toward chemotherapy.
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To begin its development of physical activity interventions, Hopelab, in partnership with the Robert Wood
Johnson Foundation's Pioneer Portfolio launched an online competition called Ruckus Nation on September 18, 2007. The competition was structured as a form of
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study of Re-Mission showing the impact of the game on neurological processes were presented in August 2008 at the 10th
International Congress of the Society of Behavioral Medicine. This research informed Hopelab's development of the next version of Re-Mission.
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Beale, I.L., Bradlyn, A.S., & Kato, P.M. (2003). Psychoeducational interventions with pediatric cancer patients: Part II. Effects of knowledge and skills training on health-related attitudes and behavior. Journal of Child and Family
Studies, 20(4),
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Beale, I.L., Kato, P.M., MarĂn-Bowling, V.M., Guthrie, N., Cole, S.W. (2007). Improvement in cancer-related knowledge following use of a psychoeducational video game for adolescents and young adults with cancer. Journal of
Adolescent Health, 41,
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constitute a component of a broader integrative approach to healthcare that synergistically combines rationally targeted biological and behavioral interventions to aid patients in the prevention, detection, treatment, and recovery from disease.
349:, and its objective was to generate ideas for products that will encourage children ages 11–14 to be more physically active. The competition was international in scope, open to people of all ages, with a total prize purse of more than 300,000
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weapons like chemotherapy, antibiotics and the body's natural defenses. Game play parallels real-world strategies used to fight cancer and win. More than 120 young people with cancer participated in the research and development of the games.
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Bradlyn, A.S., Kato, P.M., Beale, I.L., & Cole, S.W. (2004). Pediatric oncology professionals’ perceptions of information needs of adolescent patients with cancer. Journal of Pediatric Oncology Nursing, 21(6),
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Suzuki, L.K. & Beale, I. L. (2006). Personal web home pages of adolescents with cancer: Self-presentation, information dissemination, and interpersonal connection. Journal of Pediatric Oncology Nursing, 23(3),
324:), they also work to encourage childhood physical activity (Zamzee), design family-strengthening tools for young mothers and their babies, and help teenagers cultivate emotion-regulating strategies and skills.
389:, among others. The game was designed to engage young cancer patients through entertaining game play while impacting specific psychological and behavioral outcomes associated with successful cancer treatment.
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Suzuki, L.K. & Kato, P.M. (2003). Psychosocial support for patients in pediatric oncology: The influences of parents, schools, peers, and technology. Journal of Pediatric Oncology Nursing, 20(4), 159-174.
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Suzuki, L.K. & Calzo, J.P. (2004). The search for peer advice in cyberspace: An examination of teen bulletin boards about health and sexuality. Journal of Applied Developmental Psychology, 25(6), 685-698.
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Beale, I.L., MarĂn-Bowling, V.M., Guthrie, N., Kato, P.M. (2006). Young cancer patients’ perceptions of a video game used to promote self-care. International Electronic Journal of Health Education. In press.
408:. The study enrolled 375 cancer patients aged 13–29 at 34 medical centers in the United States, Canada, and Australia. Subjects received either computers pre-loaded with a popular commercial video game (the
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Bradlyn, A.S., Beale, I.L., & Kato, P.M. (2003). Psychoeducational interventions with pediatric cancer patients: Part I. Patient information and knowledge. Journal of Child and Family Studies, 12(3),
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Chen, E., Cole, S.W., & Kato, P.M. (2004). A review of empirically supported psychosocial interventions for pain and adherence outcomes in sickle cell disease. Journal of Pediatric Psychology, 29(3),
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In 2015, Zamzee was acquired by Welltok, developers of the CaféWell Health Optimization Platform. As part of Welltok, Zamzee will continue to help kids and families lead healthier, more active lives.
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Beale, I. L. (2005). Scaffolding and integrated assessment in computer assisted learning (CAL) for children with learning disabilities. Australasian Journal of Educational Technology, 21(2), 173-191.
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Kato, P.M. & Beale, I. L. (2006). Factors affecting acceptability to young cancer patients of a psychoeducational video game about cancer. Journal of Pediatric Oncology Nursing, 23(5), 269-275.
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Kato, P.M., Cole, S.W., Bradlyn, A.S., Pollock, B.H. (2008). A Video Game Improves Behavioral Outcomes in Adolescents and Young Adults With Cancer: A Randomized Trial. Pediatrics, 122, e305-e317.
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private operating foundation based in San Francisco, California. The foundation was established in 2001 by Pam Omidyar and is part of the Omidyar Group of philanthropic enterprises.
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2008, 10 category winners, one grand prize winner, and one grand prize honorable mention were announced at an event at the de Young Museum of Fine Arts in San Francisco, California.
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Hopelab works closely with academic researchers, design firms, and healthcare systems, and has developed an approach that combines behavioral psychology with socially aware design.
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As part of Hopelab's development approach, the foundation works with research partners and organizations to scale projects more broadly. Current partnerships of Hopelab include:
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genre. The game was conceived by Pam Omidyar and designed based on Hopelab research, direct input from young cancer patients and oncology doctors and nurses, and game developer
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Schiffman, J.D., Csongradi, E., & Suzuki, L.K. (2008). Internet use among adolescents and young adults (AYA) with cancer. Pediatric Blood & Cancer, 51(3), 410-415.
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Beale, I. L. (2006). Scholarly literature review: Efficacy of psychological interventions for pediatric chronic illness. Journal of Pediatric Psychology, 31(5), 437-451.
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and dependent-care advice given by pediatric oncology nurses*. Journal of Pediatric Oncology Nursing, 21(4), 214-222. *Note: Winner of “The 2004 APON Writing Award”
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is a social innovation lab focused on designing science-based technologies to improve the health and well-being of teens and young adults. They are a
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Beale, I.L. (2002). An evaluation model for psychoeducational interventions using interactive multimedia. CyberPsychology and Behavior,5(6), 565-580.
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Tate, R., Haritatos, J., & Cole, S. (2009). Hopelab's Approach to Re-Mission. International Journal of Learning and Media; 1(1), 29-35.
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Hopelab conducted an international, multicenter randomized controlled trial to gauge the efficacy of Re-Mission as it relates to
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Cole, S.W., Yoo, D.J., Knutson, B. (2012). Interactivity and Reward-Related Neural Activation During a Serious Videogame.
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copies of Re-Mission to its members at no cost. Hopelab has also partnered with Starlight Children's Foundation and the
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to measure levels of prescribed chemotherapy in the bodies of study participants rather than subjective
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655:"Online game for teens tackles obesity with a bit of fun” The Independent (September 5, 2011)
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video game for teens and young adults with cancer. Released on April 3, 2006, the game is a
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of the Zamzee product, introducing features like Zamzee Family View and Zamzee for Groups.
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Pollock, Brad H.; Bradlyn, Andrew S.; Cole, Steve W.; Kato, Pamela M. (1 August 2008).
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Baggott, C., Beale, I.L., Dodd, M.J., & Kato, P.M. (2004). A survey of self-care
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The organization's aim is to improve health outcomes for young people with cancer (
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It may require cleanup to comply with Knowledge's content policies, particularly
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where teens and young adults can share information and support each other.
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422:. Notably, to ascertain treatment compliance, researches used objective
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2007, CIGNA HealthCare announced a partnership with Hopelab in which
852:"Zamzee, With Backing From Omidyar, Takes On Teen Physical Activity"
658:"Serious Games aiding young cancer patients” Examiner (June 4, 2011)
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external links, and converting useful links where appropriate into
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Knutson, Brian; Yoo, Daniel J.; Cole, Steven W. (19 March 2012).
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Re-Mission main site supporting game orders and online community
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Research and product development are led by Dr. Jana Haritatos.
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626:"Game developers use entertainment to boost cancer therapy”
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620:"If Sitting Is the New Smoking, How Do We Kick the Habit?”
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Hopelab conducted additional research to understand the
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A major contributor to this article appears to have a
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emotions and shifting attitudes about chemotherapy.
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674:"Video Game Helps Young Cancer Patients Take Meds"
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90:may not follow Knowledge's policies or guidelines
447:French. The Re-Mission website also includes an
1156:Mental health organizations based in California
680:"Startup Uses Video Games to Heal Young People"
524:Hopelab research and journal articles include:
438:that make Re-Mission effective. Results of an
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638:"Learning to Game Our Way to Better Health”
614:"The Challenge Of Good Intentions At Scale”
463:(ESA) Foundation to distribute Re-Mission.
64:Learn how and when to remove these messages
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828:"Virtual World Takes on Childhood Obesity"
692:"OMG! Denver Girls Txt It! Game Is Winner"
404:treatments, cancer-related knowledge, and
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201:Learn how and when to remove this message
183:Learn how and when to remove this message
126:Learn how and when to remove this message
682:San Francisco Chronicle (August 4, 2008)
608:"How Texting Could Save America’s Youth”
503:Nurse-Family Partnership on project work
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668:"A Video Game Helping Kids With Cancer"
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787:: CS1 maint: archived copy as title (
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644:"Video Game to Help Kids Fight Cancer”
290:and Re-Mission 2, Zamzee, Mood Meter,
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646:Scientific American (May 13, 2013)
622:Huffington Post (October 17, 2014)
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664:Korea IT Times (March 31, 2010)
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369:Hopelab's first product is the
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634:USA Today (September 19, 2013)
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1026:10.1371/journal.pone.0033909
694:Denver Post (March 30, 2008)
670:CTV Toronto (August 7, 2008)
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517:Research and publications
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975:"Cigna Newsroom - Home"
662:"Health and Videogames”
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161:neutral point of view
854:. November 29, 2010.
436:mechanisms of action
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650:"Zamzee Interview”
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1063:Hopelab.org
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498:Robin Stern
428:self-report
424:blood tests
275:Area served
1145:Categories
960:2013-11-11
876:Pediatrics
837:2020-06-02
774:2007-10-18
729:2007-10-18
699:References
419:Pediatrics
402:antibiotic
394:compliance
371:Re-Mission
365:Re-Mission
322:Re-Mission
288:Re-Mission
264:California
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