Knowledge (XXG)

Robert McCance

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Remaining at Kings College in the 1930s, McCance conducted research on himself, studying the physiological effects of salt. He would use volunteers who would eat a salt free diet, and lie sweating under heat lamps for two hours a day for 10 days, to remove salt from the body, and become salt
348:. Their work became known as the basis for modern Western nutritional thinking, with editions in print from 1940 to 2002. McCance and Widdowson played a leading part in wartime rationing and 1940s government nutrition efforts. 1193: 656: 309:. This led to further research which established that infants with salt deficiency, excreted little salt. A later line of research, initiated with a patient who had 378:
After the war, in 1945 a personal chair was created for him and he became the first professor of experimental medicine in the UK. He was later the director of the
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led to research which established that the amount of iron in the body is regulated, not by intestinal excretion as had been taught, but by controlled absorption.
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and other nutrients, which led to a long series of metabolic studies. This research described the result, which shown that
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to the bread mix during preparation.. This led to legislation, which is still in effect today, which ensures that
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at his diabetic clinic and McCance became interested in diabetes, particularly in one of the complications of
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Widdowson, E. M. (1995). "Robert Alexander McCance. 9 December 1898 – 5 March 1993".
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Widdowson, EM (1995). "Robert Alexander McCance – 9 December 1898 – 5 March 1993".
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interfered with calcium absorption, which could be mitigated by adding
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deficient. This would lead to suffering in the volunteers including
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is added to the bread mix, to ensure sufficient calcium uptake.
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when he conducted research into the absorption and excretion of
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Born in Ulster, the son of a linen merchant, he was educated at
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McCance & Widdowson – A Scientific Partnership of 60 years
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Research conducted by McCance led to the introduction of the
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and was the first Professor of Experimental Medicine at the
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McCance and Widdowson: A Scientific Partnership of 60 Years
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The Chemistry of Flesh Foods and their Losses on Cooking
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The Chemistry of Flesh Foods and their Losses on Cooking
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to the Royal College of Physicians, on the subject of
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Biographical Memoirs of Fellows of the Royal Society
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Biographical Memoirs of Fellows of the Royal Society
1116: 1039: 956: 879: 802: 737: 673: 187: 169: 150: 120: 98: 88: 78: 60: 39: 23: 260:flying an observation aircraft from the warship 1194:Commanders of the Order of the British Empire 650: 446:Royal College of Paediatrics and Child Health 8: 344:in 1940 in collaboration with his colleague 657: 643: 635: 20: 264:. From 1919 he read Natural Sciences at 16:British doctor and scientist (1898–1993) 457: 516: 514: 512: 510: 508: 506: 504: 326:Medical problems in mineral metabolism 316:With colleague H. Shipp, he published 7: 1199:Recipients of the James Spence Medal 398:in 1953. He died on 5 March 1993 in 320:in 1933. In 1936, he delivered the 382:'s infantile malnutrition unit in 14: 1179:People educated at St Bees School 526:Munks Roll – Lives of the Fellows 342:The Chemical Composition of Foods 1184:Royal Naval Air Service aviators 421: 407: 256:, before wartime service in the 31: 272:in London. While studying with 1: 899:Richard Worthington Smithells 858:Frederick John William Miller 787:Seymour Donald Mayneord Court 1189:Fellows of the Royal Society 618:"The Robert McCance Lecture" 392:Fellow of the Royal Society 1215: 781:Ronald Stanley Illingworth 710:Robert Royston Amos Coombs 522:"Robert Alexander McCance" 104:Iron regulation mechanism. 199: 194:Frederick Gowland Hopkins 143: 30: 380:Medical Research Council 311:polycythaemia rubra vera 206:Robert Alexander McCance 102:Salt deficiency effects. 1012:Jonathan Richard Sibert 846:John Peter Mills Tizard 757:Ronald Charles MacKeith 698:Lionel Sharples Penrose 692:Frank Macfarlane Burnet 442:James Spence Gold Medal 394:in 1948, and appointed 270:King's College Hospital 258:Royal Naval Air Service 242:University of Cambridge 182:University of Cambridge 178:King's College Hospital 174:Royal Naval Air Service 93:University of Cambridge 870:David Cornelius Morley 834:James W. Bruce Douglas 810:James Mourilyan Tanner 588:10.1098/rsbm.1995.0016 479:10.1098/rsbm.1995.0016 911:Osmund Royle Reynolds 793:Kenneth William Cross 745:Douglas Vernon Hubble 681:Alan Moncrieff (1960) 332:, he was promoted to 1071:Albert Aynsley-Green 266:Cambridge University 216:(9 December 1898 in 154:Mineral metabolism, 917:Richard H. R. White 828:John Oldroyd Forfar 763:Cyril Astley Clarke 722:Donald W. Winnicott 390:. He was elected a 322:Goulstonian Lecture 299:shortness of breath 1089:Terence Stephenson 935:Forrester Cockburn 864:Otto Herbert Wolff 840:Neil Simson Gordon 769:Edward John Bowlby 667:James Spence Medal 665:Recipients of the 436:Awards and honours 220:– 3 March 1993 in 125:James Spence Medal 1151: 1150: 982:Catherine Peckham 887:Leonard B. Strang 728:Geoffrey S. Dawes 369:calcium carbonate 203: 202: 145:Scientific career 1206: 1059:Anthony Costello 1053:Andrew Wilkinson 893:John Allen Davis 852:John Lewis Emery 822:Dermod MacCarthy 775:Douglas Gairdner 659: 652: 645: 636: 629: 628: 626: 624: 614: 608: 607: 571: 565: 548: 542: 541: 539: 537: 518: 499: 498: 462: 431: 426: 425: 424: 417: 415:Biography portal 412: 411: 410: 224:) was a British 189:Doctoral advisor 116:Modern nutrition 67: 49: 47: 35: 21: 1214: 1213: 1209: 1208: 1207: 1205: 1204: 1203: 1174:Food scientists 1154: 1153: 1152: 1147: 1112: 1065:Sheila Shribman 1035: 1018:Victor Dubowitz 952: 875: 816:Elsie Widdowson 798: 733: 704:Cicely Williams 669: 663: 633: 632: 622: 620: 616: 615: 611: 573: 572: 568: 549: 545: 535: 533: 520: 519: 502: 464: 463: 459: 454: 438: 429:Medicine portal 427: 422: 420: 413: 408: 406: 346:Elsie Widdowson 290: 282:sodium chloride 262:HMS Indomitable 254:St. Bees School 250: 136: 132: 128: 115: 110: 105: 103: 89:Alma mater 74: 69: 65: 56: 51: 50:9 December 1898 45: 43: 26: 17: 12: 11: 5: 1212: 1210: 1202: 1201: 1196: 1191: 1186: 1181: 1176: 1171: 1166: 1156: 1155: 1149: 1148: 1146: 1145: 1142:Andrew Pollard 1139: 1133: 1130:Henry Halliday 1127: 1120: 1118: 1114: 1113: 1111: 1110: 1104: 1098: 1095:Anne Greenough 1092: 1086: 1080: 1074: 1068: 1062: 1056: 1050: 1047:Malcolm Levene 1043: 1041: 1037: 1036: 1034: 1033: 1027: 1021: 1015: 1009: 1003: 1000:Cyril Chantler 997: 991: 985: 979: 976:Martin Barratt 973: 967: 960: 958: 954: 953: 951: 950: 944: 938: 932: 929:Barbara Ansell 926: 920: 914: 908: 902: 896: 890: 883: 881: 877: 876: 874: 873: 867: 861: 855: 849: 843: 837: 831: 825: 819: 813: 806: 804: 800: 799: 797: 796: 790: 784: 778: 772: 766: 760: 754: 748: 741: 739: 735: 734: 732: 731: 725: 719: 713: 707: 701: 695: 689: 686:Robert McCance 683: 677: 675: 671: 670: 664: 662: 661: 654: 647: 639: 631: 630: 609: 566: 543: 500: 456: 455: 453: 450: 449: 448: 437: 434: 433: 432: 418: 289: 286: 274:R. D. Lawrence 249: 246: 201: 200: 197: 196: 191: 185: 184: 171: 167: 166: 152: 148: 147: 141: 140: 122: 118: 117: 100: 99:Known for 96: 95: 90: 86: 85: 80: 76: 75: 70: 68:(aged 95) 62: 58: 57: 52: 41: 37: 36: 28: 27: 25:Robert McCance 24: 15: 13: 10: 9: 6: 4: 3: 2: 1211: 1200: 1197: 1195: 1192: 1190: 1187: 1185: 1182: 1180: 1177: 1175: 1172: 1170: 1167: 1165: 1162: 1161: 1159: 1143: 1140: 1137: 1136:Imti Choonara 1134: 1131: 1128: 1125: 1124:Catherine Law 1122: 1121: 1119: 1115: 1108: 1105: 1102: 1101:Frances Cowan 1099: 1096: 1093: 1090: 1087: 1084: 1081: 1078: 1075: 1072: 1069: 1066: 1063: 1060: 1057: 1054: 1051: 1048: 1045: 1044: 1042: 1038: 1031: 1030:Neil McIntosh 1028: 1025: 1022: 1019: 1016: 1013: 1010: 1007: 1004: 1001: 998: 995: 992: 989: 986: 983: 980: 977: 974: 971: 970:Peter M. Dunn 968: 965: 962: 961: 959: 955: 948: 945: 942: 939: 936: 933: 930: 927: 924: 921: 918: 915: 912: 909: 906: 903: 900: 897: 894: 891: 888: 885: 884: 882: 878: 871: 868: 865: 862: 859: 856: 853: 850: 847: 844: 841: 838: 835: 832: 829: 826: 823: 820: 817: 814: 811: 808: 807: 805: 801: 794: 791: 788: 785: 782: 779: 776: 773: 770: 767: 764: 761: 758: 755: 752: 751:Wilfrid Payne 749: 746: 743: 742: 740: 736: 729: 726: 723: 720: 717: 716:Mary Sheridan 714: 711: 708: 705: 702: 699: 696: 693: 690: 687: 684: 682: 679: 678: 676: 672: 668: 660: 655: 653: 648: 646: 641: 640: 637: 619: 613: 610: 605: 601: 597: 593: 589: 585: 581: 577: 570: 567: 564: 563: 559: 553: 547: 544: 531: 527: 523: 517: 515: 513: 511: 509: 507: 505: 501: 496: 492: 488: 484: 480: 476: 472: 468: 461: 458: 451: 447: 443: 440: 439: 435: 430: 419: 416: 405: 403: 401: 397: 393: 389: 385: 381: 376: 374: 370: 366: 362: 358: 354: 353:National Loaf 349: 347: 343: 339: 336:and moved to 335: 331: 327: 323: 319: 314: 312: 308: 304: 300: 296: 287: 285: 283: 279: 278:diabetic coma 275: 271: 267: 263: 259: 255: 247: 245: 243: 239: 235: 231: 227: 226:paediatrician 223: 219: 215: 211: 207: 198: 195: 192: 190: 186: 183: 179: 175: 172: 168: 165: 161: 157: 153: 149: 146: 142: 139: 135: 131: 126: 123: 119: 113: 108: 107:National Loaf 101: 97: 94: 91: 87: 84: 81: 77: 73: 63: 59: 55: 42: 38: 34: 29: 22: 19: 1083:David Dunger 1077:Ieuan Hughes 964:Hugh Jackson 941:David Harvey 685: 621:. Retrieved 612: 579: 575: 569: 555: 551: 550:Ashwell, M. 546: 534:. Retrieved 529: 525: 470: 466: 460: 377: 350: 341: 325: 317: 315: 291: 251: 238:nutritionist 230:physiologist 205: 204: 170:Institutions 160:Biochemistry 144: 111: 66:(1993-03-05) 64:5 March 1993 18: 1169:1993 deaths 1164:1898 births 994:Lewis Spitz 365:brown flour 301:as well as 79:Nationality 1158:Categories 1107:Alan Emond 1024:Alan Craft 1006:Alan Lucas 988:David Hall 947:Roy Meadow 923:David Hull 905:June Lloyd 623:17 October 582:: 261–80. 562:0907667074 536:19 January 473:: 261–80. 452:References 330:J. A. Ryle 234:biochemist 156:Pediatrics 46:1898-12-09 400:Cambridge 338:Cambridge 222:Cambridge 164:Nutrition 72:Cambridge 604:37304802 596:11615357 495:37304802 487:11615357 303:anorexia 384:Kampala 361:phytate 357:calcium 127:in 1961 83:British 1144:(2023) 1138:(2022) 1132:(2021) 1126:(2020) 1109:(2019) 1103:(2018) 1097:(2017) 1091:(2016) 1085:(2015) 1079:(2014) 1073:(2013) 1067:(2012) 1061:(2011) 1055:(2011) 1049:(2010) 1032:(2009) 1026:(2008) 1020:(2007) 1014:(2006) 1008:(2006) 1002:(2005) 996:(2004) 990:(2004) 984:(2003) 978:(2002) 972:(2001) 966:(2000) 949:(1999) 943:(1999) 937:(1998) 931:(1997) 925:(1996) 919:(1995) 913:(1994) 907:(1993) 901:(1992) 895:(1991) 889:(1990) 872:(1989) 866:(1988) 860:(1987) 854:(1987) 848:(1986) 842:(1985) 836:(1984) 830:(1983) 824:(1982) 818:(1981) 812:(1980) 795:(1979) 789:(1978) 783:(1977) 777:(1976) 771:(1974) 765:(1973) 759:(1972) 753:(1971) 747:(1970) 730:(1969) 724:(1968) 718:(1968) 712:(1967) 706:(1965) 700:(1964) 694:(1963) 688:(1961) 602:  594:  560:  493:  485:  388:Uganda 334:Reader 307:nausea 295:cramps 288:Career 218:Ulster 151:Fields 121:Awards 54:Ulster 1117:2020s 1040:2010s 957:2000s 880:1990s 803:1980s 738:1970s 674:1960s 600:S2CID 556:1993 491:S2CID 373:chalk 625:2012 592:PMID 558:ISBN 538:2018 483:PMID 305:and 297:and 248:Life 236:and 138:FRCP 61:Died 40:Born 584:doi 475:doi 396:CBE 363:in 214:FRS 210:CBE 134:CBE 130:FRS 1160:: 598:. 590:. 580:41 578:. 530:IX 528:. 524:. 503:^ 489:. 481:. 471:41 469:. 444:, 402:. 386:, 280:, 244:. 232:, 228:, 212:, 208:, 180:, 176:, 162:, 158:, 658:e 651:t 644:v 627:. 606:. 586:: 540:. 497:. 477:: 114:, 109:. 48:) 44:(

Index


Ulster
Cambridge
British
University of Cambridge
National Loaf
James Spence Medal
FRS
CBE
FRCP
Pediatrics
Biochemistry
Nutrition
Royal Naval Air Service
King's College Hospital
University of Cambridge
Doctoral advisor
Frederick Gowland Hopkins
CBE
FRS
Ulster
Cambridge
paediatrician
physiologist
biochemist
nutritionist
University of Cambridge
St. Bees School
Royal Naval Air Service
HMS Indomitable

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