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Remaining at Kings
College in the 1930s, McCance conducted research on himself, studying the physiological effects of salt. He would use volunteers who would eat a salt free diet, and lie sweating under heat lamps for two hours a day for 10 days, to remove salt from the body, and become salt
348:. Their work became known as the basis for modern Western nutritional thinking, with editions in print from 1940 to 2002. McCance and Widdowson played a leading part in wartime rationing and 1940s government nutrition efforts.
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309:. This led to further research which established that infants with salt deficiency, excreted little salt. A later line of research, initiated with a patient who had
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After the war, in 1945 a personal chair was created for him and he became the first professor of experimental medicine in the UK. He was later the director of the
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led to research which established that the amount of iron in the body is regulated, not by intestinal excretion as had been taught, but by controlled absorption.
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and other nutrients, which led to a long series of metabolic studies. This research described the result, which shown that
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to the bread mix during preparation.. This led to legislation, which is still in effect today, which ensures that
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at his diabetic clinic and McCance became interested in diabetes, particularly in one of the complications of
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Widdowson, E. M. (1995). "Robert
Alexander McCance. 9 December 1898 – 5 March 1993".
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Widdowson, EM (1995). "Robert
Alexander McCance – 9 December 1898 – 5 March 1993".
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284:(salt) deficiency. He then began a scientific career in the study of nutrition.
532:. Royal College of Physicians: Royal College of Physicians: 327. 21 August 2013
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interfered with calcium absorption, which could be mitigated by adding
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deficient. This would lead to suffering in the volunteers including
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is added to the bread mix, to ensure sufficient calcium uptake.
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when he conducted research into the absorption and excretion of
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Born in Ulster, the son of a linen merchant, he was educated at
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McCance & Widdowson – A Scientific
Partnership of 60 years
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Research conducted by McCance led to the introduction of the
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and was the first
Professor of Experimental Medicine at the
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McCance and
Widdowson: A Scientific Partnership of 60 Years
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The
Chemistry of Flesh Foods and their Losses on Cooking
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The
Chemistry of Flesh Foods and their Losses on Cooking
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to the Royal
College of Physicians, on the subject of
340:. He wrote the long-standard text and reference book
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Biographical
Memoirs of Fellows of the Royal Society
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Biographical Memoirs of Fellows of the Royal Society
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344:in 1940 in collaboration with his colleague
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326:Medical problems in mineral metabolism
316:With colleague H. Shipp, he published
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1199:Recipients of the James Spence Medal
398:in 1953. He died on 5 March 1993 in
320:in 1933. In 1936, he delivered the
382:'s infantile malnutrition unit in
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1179:People educated at St Bees School
526:Munks Roll – Lives of the Fellows
342:The Chemical Composition of Foods
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256:, before wartime service in the
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272:in London. While studying with
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899:Richard Worthington Smithells
858:Frederick John William Miller
787:Seymour Donald Mayneord Court
1189:Fellows of the Royal Society
618:"The Robert McCance Lecture"
392:Fellow of the Royal Society
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781:Ronald Stanley Illingworth
710:Robert Royston Amos Coombs
522:"Robert Alexander McCance"
104:Iron regulation mechanism.
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194:Frederick Gowland Hopkins
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380:Medical Research Council
311:polycythaemia rubra vera
206:Robert Alexander McCance
102:Salt deficiency effects.
1012:Jonathan Richard Sibert
846:John Peter Mills Tizard
757:Ronald Charles MacKeith
698:Lionel Sharples Penrose
692:Frank Macfarlane Burnet
442:James Spence Gold Medal
394:in 1948, and appointed
270:King's College Hospital
258:Royal Naval Air Service
242:University of Cambridge
182:University of Cambridge
178:King's College Hospital
174:Royal Naval Air Service
93:University of Cambridge
870:David Cornelius Morley
834:James W. Bruce Douglas
810:James Mourilyan Tanner
588:10.1098/rsbm.1995.0016
479:10.1098/rsbm.1995.0016
911:Osmund Royle Reynolds
793:Kenneth William Cross
745:Douglas Vernon Hubble
681:Alan Moncrieff (1960)
332:, he was promoted to
1071:Albert Aynsley-Green
266:Cambridge University
216:(9 December 1898 in
154:Mineral metabolism,
917:Richard H. R. White
828:John Oldroyd Forfar
763:Cyril Astley Clarke
722:Donald W. Winnicott
390:. He was elected a
322:Goulstonian Lecture
299:shortness of breath
1089:Terence Stephenson
935:Forrester Cockburn
864:Otto Herbert Wolff
840:Neil Simson Gordon
769:Edward John Bowlby
667:James Spence Medal
665:Recipients of the
436:Awards and honours
220:– 3 March 1993 in
125:James Spence Medal
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982:Catherine Peckham
887:Leonard B. Strang
728:Geoffrey S. Dawes
369:calcium carbonate
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145:Scientific career
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238:nutritionist
230:physiologist
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170:Institutions
160:Biochemistry
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66:(1993-03-05)
64:5 March 1993
18:
1169:1993 deaths
1164:1898 births
994:Lewis Spitz
365:brown flour
301:as well as
79:Nationality
1158:Categories
1107:Alan Emond
1024:Alan Craft
1006:Alan Lucas
988:David Hall
947:Roy Meadow
923:David Hull
905:June Lloyd
623:17 October
582:: 261–80.
562:0907667074
536:19 January
473:: 261–80.
452:References
330:J. A. Ryle
234:biochemist
156:Pediatrics
46:1898-12-09
400:Cambridge
338:Cambridge
222:Cambridge
164:Nutrition
72:Cambridge
604:37304802
596:11615357
495:37304802
487:11615357
303:anorexia
384:Kampala
361:phytate
357:calcium
127:in 1961
83:British
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388:Uganda
334:Reader
307:nausea
295:cramps
288:Career
218:Ulster
151:Fields
121:Awards
54:Ulster
1117:2020s
1040:2010s
957:2000s
880:1990s
803:1980s
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674:1960s
600:S2CID
556:1993
491:S2CID
373:chalk
625:2012
592:PMID
558:ISBN
538:2018
483:PMID
305:and
297:and
248:Life
236:and
138:FRCP
61:Died
40:Born
584:doi
475:doi
396:CBE
363:in
214:FRS
210:CBE
134:CBE
130:FRS
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