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Statistical significance

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Researchers focusing solely on whether their results are statistically significant might report findings that are not substantive and not replicable. There is also a difference between statistical significance and practical significance. A study that is found to be statistically significant may not
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than a one-tailed test, because the rejection region for a one-tailed test is concentrated on one end of the null distribution and is twice the size (5% vs. 2.5%) of each rejection region for a two-tailed test. As a result, the null hypothesis can be rejected with a less extreme result if a
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A statistically significant result may not be easy to reproduce. In particular, some statistically significant results will in fact be false positives. Each failed attempt to reproduce a result increases the likelihood that the result was a false positive.
802:-values as continuous indices, thereby discarding thresholds and statistical significance. Additionally, the change to 0.005 would increase the likelihood of false negatives, whereby the effect being studied is real, but the test fails to show it. 418:
should be rejected or retained. The null hypothesis is the hypothesis that no effect exists in the phenomenon being studied. For the null hypothesis to be rejected, an observed result has to be statistically significant, i.e. the observed
1934:"Conclusions about statistical significance are possible with the help of the confidence interval. If the confidence interval does not include the value of zero effect, it can be assumed that there is a statistically significant result." 786: â‰€ 0.05') as a license for making a claim of a scientific finding (or implied truth) leads to considerable distortion of the scientific process". In 2017, a group of 72 authors proposed to enhance reproducibility by changing the 810:
We conclude, based on our review of the articles in this special issue and the broader literature, that it is time to stop using the term "statistically significant" entirely. Nor should variants such as "significantly different,"
730:=5%, was being relied on too heavily as the primary measure of validity of a hypothesis. Some journals encouraged authors to do more detailed analysis than just a statistical significance test. In social psychology, the journal 577:
one-tailed test was used. The one-tailed test is only more powerful than a two-tailed test if the specified direction of the alternative hypothesis is correct. If it is wrong, however, then the one-tailed test has no power.
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Effect size is a measure of a study's practical significance. A statistically significant result may have a weak effect. To gauge the research significance of their result, researchers are encouraged to always report an
141:-value of an observed effect is less than (or equal to) the significance level, an investigator may conclude that the effect reflects the characteristics of the whole population, thereby rejecting the null hypothesis. 805:
In 2019, over 800 statisticians and scientists signed a message calling for the abandonment of the term "statistical significance" in science, and the ASA published a further official statement declaring (page 2):
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Ioannidis, John P. A.; Ware, Jennifer J.; Wagenmakers, Eric-Jan; Simonsohn, Uri; Chambers, Christopher D.; Button, Katherine S.; Bishop, Dorothy V. M.; Nosek, Brian A.; MunafĂČ, Marcus R. (January 2017).
743:-values, as Basic and Applied Social Psychology recently did, is not going to solve the problem because it is merely treating a symptom of the problem. There is nothing wrong with hypothesis testing and 3171:. There is growing determination to reform statistical analysis... Some suggest changing statistical methods, whereas others would do away with a threshold for defining "significant" results." (p. 63.) 1622: 2615: 790:-value threshold for statistical significance from 0.05 to 0.005. Other researchers responded that imposing a more stringent significance threshold would aggravate problems such as 450:-value, which is the probability of observing an effect of the same magnitude or more extreme given that the null hypothesis is true. The null hypothesis is rejected if the 112: 361:
instead. This is the probability of not rejecting the null hypothesis given that it is true. Confidence levels and confidence intervals were introduced by Neyman in 1937.
2001: 835: 523: 492: 472: 441: 334: 294: 259: 239: 53: 4783: 683: 3235: 747:-values per se as long as authors, reviewers, and action editors use them correctly." Some statisticians prefer to use alternative measures of evidence, such as 5288: 314: 81: 5438: 5062: 3275: 3703: 736:
banned the use of significance testing altogether from papers it published, requiring authors to use other measures to evaluate hypotheses and impact.
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can avoid confidence levels, but also requires making additional assumptions, and may not necessarily improve practice regarding statistical testing.
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Myers, Jerome L.; Well, Arnold D.; Lorch, Robert F. Jr. (2010). "Developing fundamentals of hypothesis testing using the binomial distribution".
678:-values. An effect size measure quantifies the strength of an effect, such as the distance between two means in units of standard deviation (cf. 114:. The significance level for a study is chosen before data collection, and is typically set to 5% or much lower—depending on the field of study. 3256: 3203: 2599: 2566: 2255: 2230: 2194: 2169: 2144: 2119: 2086: 2061: 1876: 1840: 1815: 1784: 1745: 1712: 1684: 1660: 1597: 1475: 1450: 1415: 1390: 1365: 1332: 1307: 1279: 1147: 1031: 995: 967: 939: 264:
Despite his initial suggestion of 0.05 as a significance level, Fisher did not intend this cutoff value to be fixed. In his 1956 publication
3295:. The earth is round (p<.05). American Psychologist. Vol 49, p. 997-1003. Reviews problems with null hypothesis statistical testing. 3698: 3398: 1495: 4302: 3450: 3288: 732: 337: 5690: 209:. Fisher suggested a probability of one in twenty (0.05) as a convenient cutoff level to reject the null hypothesis. In a 1933 paper, 3186: 5085: 4977: 316:
below which the null hypothesis is rejected even though by assumption it were true, and something else is going on. This means that
1142:. Wiley Reference Series in Biostatistics (3rd ed.). West Sussex, United Kingdom: John Wiley & Sons Ltd. pp. 35–36. 5263: 5137: 775: 541:-value is less than (or equal to) 5%. When drawing data from a sample, this means that the rejection region comprises 5% of the 5321: 4982: 4727: 4098: 3688: 4312: 5372: 4584: 4391: 4280: 4238: 2701: 1219:
Sham, Pak C.; Purcell, Shaun M (17 April 2014). "Statistical power and significance testing in large-scale genetic studies".
884: 370: 20: 3477: 3359: 3366:" (February 1994): article by Bruce Thompon hosted by the ERIC Clearinghouse on Assessment and Evaluation, Washington, D.C. 724:
Starting in the 2010s, some journals began questioning whether significance testing, and particularly using a threshold of
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is also the probability of mistakenly rejecting the null hypothesis, if the null hypothesis is true. This is also called
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Compassionate Statistics: Applied Quantitative Analysis for Social Services (With exercises and instructions in SPSS)
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Statistical significance plays a pivotal role in statistical hypothesis testing. It is used to determine whether the
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is not the same as research significance, theoretical significance, or practical significance. For example, the term
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This technique for testing the statistical significance of results was developed in the early 20th century. The term
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Neyman, J.; Pearson, E.S. (1933). "The testing of statistical hypotheses in relation to probabilities a priori".
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advanced the idea of statistical hypothesis testing, which he called "tests of significance", in his publication
55:, is the probability of the study rejecting the null hypothesis, given that the null hypothesis is true; and the 5240: 1835:. Essays in Cognitive Psychology (1st ed.). East Sussex, United Kingdom: Psychology Press. pp. 29–48. 5610: 5377: 4925: 4890: 4854: 4639: 4081: 3990: 3949: 3861: 3552: 3391: 881: 4647: 4631: 2584:
Principles, Problems, Practices, and Prospects Reproducibility: Principles, Problems, Practices, and Prospects
5519: 5132: 5072: 5009: 4369: 4231: 4221: 4071: 3985: 3373:" (no date): an article from the Statistical Assessment Service at George Mason University, Washington, D.C. 3142:
Lydia Denworth, "A Significant Problem: Standard scientific methods are under fire. Will anything change?",
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Myers, Jerome L.; Well, Arnold D.; Lorch, Robert F. Jr. (2010). "The t distribution and its applications".
837:," and "nonsignificant" survive, whether expressed in words, by asterisks in a table, or in some other way. 5557: 5487: 4972: 4859: 3856: 3753: 3660: 3539: 3438: 763: 561: 378: 130: 5678: 4556: 5582: 5524: 5467: 5293: 5186: 5095: 4821: 4705: 4564: 4446: 4438: 4253: 4149: 4127: 4086: 4051: 4018: 3964: 3939: 3894: 3833: 3793: 3595: 3418: 3030: 890: 872: 542: 407: 165: 153: 126: 5661: 4551: 3207: 2986:
Amrhein, Valentin; Greenland, Sander (2017). "Remove, rather than redefine, statistical significance".
2726: 849: 1999:(1937). "Outline of a Theory of Statistical Estimation Based on the Classical Theory of Probability". 5505: 5080: 5029: 5005: 4967: 4885: 4864: 4816: 4695: 4673: 4642: 4428: 4379: 4297: 4270: 4226: 4182: 3944: 3720: 3600: 3312: 3069: 2672: 2010: 1901: 1092: 175: 2271:
Clarke, GM; Anderson, CA; Pettersson, FH; Cardon, LR; Morris, AP; Zondervan, KT (February 6, 2011).
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Redmond, Carol; Colton, Theodore (2001). "Clinical significance versus statistical significance".
782:-values, saying that "the widespread use of 'statistical significance' (generally interpreted as ' 5666: 5477: 5331: 5176: 5052: 4949: 4933: 4910: 4687: 4421: 4404: 4364: 4275: 4170: 4132: 4103: 4063: 4023: 3969: 3886: 3572: 3567: 3011: 2539: 2388: 2034: 2026: 1917: 1244: 855: 714: 604: 586: 2222: 877: 814: 3282:
Vol. 506, p. 150-152 (open access). Highlights common misunderstandings about the p value.
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The Cult of Statistical Significance: How the Standard Error Costs Us Jobs, Justice, and Lives
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The widespread abuse of statistical significance represents an important topic of research in
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Handbook of Research Methods: A Guide for Practitioners and Students in the Social Science
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at birth, assuming a null hypothesis of equal probability of male and female births; see
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Understanding The New Statistics: Effect Sizes, Confidence Intervals, and Meta-Analysis
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Understanding The New Statistics: Effect Sizes, Confidence Intervals, and Meta-Analysis
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To determine whether a result is statistically significant, a researcher calculates a
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Cumming, Geoff (2011). "From null hypothesis significance to testing effect sizes".
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Brian, Éric; Jaisson, Marie (2007). "Physico-Theology and Mathematics (1710–1794)".
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he recommended that significance levels be set according to specific circumstances.
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Beyond Significance Testing: Reforming Data Analysis Methods in Behavioral Research
2543: 1996: 752: 530: 499: 498:, and is the probability of rejecting the null hypothesis given that it is true (a 214: 210: 3125: 3106: 2784: 679: 3356: 3213:
Thompson, Bruce (2004). "The "significance" crisis in psychology and education".
2745: 2424: 2338: 2250:(1st ed.). Pittsburgh, PA: University of Pittsburgh Press. pp. Ii–Iii. 1533:"Balancing statistical and clinical significance in evaluating treatment effects" 1264: 5605: 5567: 5250: 5151: 5013: 4826: 4793: 4285: 4202: 4197: 3841: 3798: 3778: 3758: 3748: 3517: 3226: 2801:"Thou Shalt Not Bear False Witness Against Null Hypothesis Significance Testing" 1729: 1441:(1st ed.). Cambridge, United Kingdom: Cambridge University Press. pp.  1023: 900: 863: 671: 664: 620: 3325: 3300: 3082: 3057: 2371:
Carver, Ronald P. (1978). "The Case Against Statistical Significance Testing".
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Risk, Chance, and Causation: Investigating the Origins and Treatment of Disease
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Prel, Jean-Baptist du; Hommel, Gerhard; Röhrig, Bernd; Blettner, Maria (2009).
4451: 3931: 3631: 3562: 3512: 3487: 3407: 3352:" contains an entry on Significance that provides some historical information. 3156: 2999: 2972: 2926: 2909: 2591: 1953: 1913: 1058: 845: 545:. These 5% can be allocated to one side of the sampling distribution, as in a 118: 2824: 2816: 2189:(1st ed.). Cambridge, UK: Cambridge University Press. pp. 146–152. 1556: 1410:(1st ed.). Thousand Oaks, CA: SAGE Publications, Inc. pp. 127–138. 934:(3rd ed.). Thousand Oaks, CA: SAGE Publications, Inc. pp. 271–316. 4604: 4456: 4076: 3871: 3783: 3768: 3763: 3728: 3160: 2875: 2248:
Shifting Standards: Experiments in Particle Physics in the Twentieth Century
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Craparo, Robert M. (2007). "Significance level". In Salkind, Neil J. (ed.).
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Other editors, commenting on this ban have noted: "Banning the reporting of
553:, with each tail (or rejection region) containing 2.5% of the distribution. 391: 3334: 3091: 3007: 2945: 2894: 2842: 2535: 2514:
Hojat, Mohammadreza; Xu, Gang (2004). "A Visitor's Guide to Effect Sizes".
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StatNews #73: Overlapping Confidence Intervals and Statistical Significance
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Hald, Anders (1998), "Chapter 4. Chance or Design: Tests of Significance",
1636: 1574: 1548: 1240: 1205: 1124: 3259:– argues that statistical significance is useful in certain circumstances. 2727:"On doing better science: From thrill of discovery to policy implications" 1503:
University of Alberta, Department of Mathematical and Statistical Sciences
615:, with significance thresholds set at a much stricter level (for example 5 537:, is 5%, and a statistically significant result is one where the observed 4120: 3738: 3615: 3610: 3605: 3577: 3264: 3105:
Wasserstein, Ronald L.; Schirm, Allen L.; Lazar, Nicole A. (2019-03-20).
867: 2936: 5625: 5326: 3168: 3149: 2478: 1327:. Vol. 3. Thousand Oaks, CA: SAGE Publications. pp. 889–891. 1196: 1179: 908:(gives examples of tests where the significance level was set too high) 382: 190: 179: 56: 2561:(Student ed.). New York, NY: Psychology Press. pp. 180–210. 646:
are not uncommon—as the number of tests performed is extremely large.
5547: 4528: 4502: 4482: 3733: 3524: 2620:-values and the Null Hypothesis Significance Testing (NHST) paradigm" 2030: 1701:
The History of Statistics: The Measurement of Uncertainty Before 1900
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Faherty, Vincent (2008). "Probability and statistical significance".
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Dalgaard, Peter (2008). "Power and the computation of sample size".
962:(3rd ed.). Milwaukee, WI: ASQ Quality Press. pp. 418–472. 27:
when a result at least as "extreme" would be very infrequent if the
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Amrhein, Valentin; Greenland, Sander; McShane, Blake (2019-03-20).
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McShane, Blake; Greenland, Sander; Amrhein, Valentin (March 2019).
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Amrhein, Valentin; Korner-Nievergelt, FrÀnzi; Roth, Tobias (2017).
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Barsh, GS; Copenhaver, GP; Gibson, G; Williams, SM (July 5, 2012).
794:; alternative propositions are thus to select and justify flexible 170:
Statistical significance dates to the 18th century, in the work of
1385:(13th ed.). Belmont, CA: Cengage Learning. pp. 185–226. 603:, statistical significance is often expressed in multiples of the 3371:
What does it mean for a result to be "statistically significant"?
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An Introduction To Experimental Design And Statistics For Biology
2081:(2nd ed.). Belmont, CA: Cengage Learning. pp. 177–205. 1018:. Statistics and Computing. New York: Springer. pp. 155–56. 3467: 2766:"The ASA's Statement on p-Values: Context, Process, and Purpose" 2056:(3rd ed.). Boston, MA: Cengage Learning. pp. 189–209. 1302:(8th ed.). Boston, MA: Cengage Learning. pp. 300–344. 5436: 5003: 4750: 4049: 3819: 3436: 3380: 3155:
for nearly a century to determine statistical significance of
2702:"P value ban: small step for a journal, giant leap for science" 2582:
Stahel, Werner (2016). "Statistical Issue in Reproducibility".
2221:(1st ed.). New Haven, CT: Yale University Press. pp.  2106:
Statistics Explained: An Introductory Guide for Life Scientists
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Mathematical Proceedings of the Cambridge Philosophical Society
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Statistics Explained: An Introductory Guide for Life Scientists
3148:, vol. 321, no. 4 (October 2019), pp. 62–67. "The use of 3376: 2273:"Basic statistical analysis in genetic case-control studies" 2246:
Franklin, Allan (2013). "Prologue: The rise of the sigmas".
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Meier, Kenneth J.; Brudney, Jeffrey L.; Bohte, John (2011).
1180:"Points of significance: Significance, P values and t-tests" 564:
specifies a direction such as whether a group of objects is
549:, or partitioned to both sides of the distribution, as in a 3350:
Earliest Known Uses of Some of the Words of Mathematics (S)
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Hinton, Perry R. (2010). "Significance, error, and power".
1470:(3rd ed.). New York, NY: Routledge. pp. 124–153. 1356:(2nd ed.). Lanham, MD: Scarecrow Press, Inc. pp.  1300:
Probability and Statistics for Engineering and the Sciences
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Applied Statistics for Public and Nonprofit Administration
1434:"Probability helps you make a decision about your results" 798:-value thresholds before collecting data, or to interpret 572:. A two-tailed test may still be used but it will be less 410:
and makes up 5% of the area under the curve (white areas).
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refers to the practical importance of a treatment effect.
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Statistical Significance: Rationale, Validity and Utility
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Measurement, Design, and Analysis: An Integrated Approach
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Poletiek, Fenna H. (2001). "Formal theories of testing".
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Philosophical Transactions of the Royal Society of London
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Borror, Connie M. (2009). "Statistical decision making".
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The use of a one-tailed test is dependent on whether the
454:-value is less than (or equal to) a predetermined level, 423:-value is less than the pre-specified significance level 2079:
The Essentials of Statistics: A Tool for Social Research
1592:. Springer Science & Business Media. pp. 1–25. 2961:"'One-size-fits-all' threshold for P values under fire" 2764:
Wasserstein, Ronald L.; Lazar, Nicole A. (2016-04-02).
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A History of Mathematical Statistics from 1750 to 1930
3301:"Scientists rise up against statistical significance" 3058:"Scientists rise up against statistical significance" 1178:
Krzywinski, Martin; Altman, Naomi (30 October 2013).
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Autoregressive conditional heteroskedasticity (ARCH)
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Experimental Design and Data Analysis for Biologists
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Conover, W.J. (1999), "Chapter 3.4: The Sign Test",
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be set ahead of time, prior to any data collection.
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Washington, DC: American Psychological Association.
568:or the performance of students on an assessment is 399:, the rejection region for a significance level of 2214: 2103: 1432: 1270:. New York, USA: Chapman & Hall/CRC. pp.  1263: 829: 517: 486: 466: 435: 328: 308: 288: 253: 233: 106: 75: 47: 2557:Pedhazur, Elazar J.; Schmelkin, Liora P. (1991). 2002:Philosophical Transactions of the Royal Society A 1381:Babbie, Earl R. (2013). "The logic of sampling". 981: 979: 2408:"Why most published research findings are false" 2322:"Guidelines for Genome-Wide Association Studies" 4837:Multivariate adaptive regression splines (MARS) 3357:The Concept of Statistical Significance Testing 1861:Quinn, Geoffrey R.; Keough, Michael J. (2002). 1085:Proceedings of the National Academy of Sciences 808: 634:In other fields of scientific research such as 2646:"Psychology Journal Bans Significance Testing" 1728:Bellhouse, David (2001), "John Arbuthnot", in 930:Sirkin, R. Mark (2005). "Two-sample t tests". 3392: 266:Statistical Methods and Scientific Inference, 148:does not imply importance here, and the term 31:were true. More precisely, a study's defined 8: 2455: 2453: 1081:"Revised standards for statistical evidence" 1806:. Edinburgh, UK: Oliver and Boyd. pp.  1655:(Third ed.), Wiley, pp. 157–176, 1167:. New York, USA: Routledge. pp. 27–28. 5446: 5433: 5350: 5156: 5025: 5000: 4771: 4747: 4475: 4258: 4059: 4046: 3829: 3816: 3455: 3446: 3433: 3399: 3385: 3377: 3159:results has contributed to an illusion of 2626:. School of Education, University of Leeds 2208: 2206: 1325:Encyclopedia of Measurement and Statistics 1009: 1007: 581:Significance thresholds in specific fields 3324: 3124: 3081: 2935: 2925: 2884: 2874: 2832: 2805:Educational and Psychological Measurement 2783: 2684: 2616:"CSSME Seminar Series: The argument over 2487: 2477: 2433: 2423: 2347: 2337: 2296: 1961: 1677:Applied Nonparametric Statistical Methods 1635: 1564: 1293: 1291: 1266:Practical Statistics for Medical Research 1195: 1114: 1104: 816: 510: 479: 459: 428: 321: 301: 281: 246: 226: 93: 68: 40: 3107:"Moving to a World Beyond "p < 0.05"" 3031:"Moving Science's Statistical Goalposts" 2187:Scientific Inference: Learning from Data 1856: 1854: 1852: 1803:Statistical Methods for Research Workers 1468:Research Design and Statistical Analysis 988:Research design and statistical analysis 953: 951: 925: 923: 921: 655:necessarily be practically significant. 390: 206:Statistical Methods for Research Workers 1679:(Second ed.), Chapman & Hall, 1590:The Descent of Human Sex Ratio at Birth 960:The Certified Quality Engineer Handbook 917: 623:particle's existence was based on the 5 5363:Kaplan–Meier estimator (product limit) 2908:Benjamin, Daniel; et al. (2018). 2859:"A manifesto for reproducible science" 2799:GarcĂ­a-PĂ©rez, Miguel A. (2016-10-05). 619:). For instance, the certainty of the 535:given that the null hypothesis is true 365:Role in statistical hypothesis testing 3276:Scientific method: Statistical errors 2644:Novella, Steven (February 25, 2015). 2516:Advances in Health Sciences Education 1703:. Harvard University Press. pp.  1489: 1487: 1079:Johnson, Valen E. (October 9, 2013). 502:). It is usually set at or below 5%. 347:Sometimes researchers talk about the 7: 5673: 5373:Accelerated failure time (AFT) model 1045: 1043: 88:by the standards of the study, when 5685: 4968:Analysis of variance (ANOVA, anova) 2910:"Redefine statistical significance" 2385:10.17763/haer.48.3.t490261645281841 733:Basic and Applied Social Psychology 406:is partitioned to both ends of the 5063:Cochran–Mantel–Haenszel statistics 3689:Pearson product-moment correlation 2661:"Psychology journal bans P values" 2528:10.1023/B:AHSE.0000038173.00909.f6 1653:Practical Nonparametric Statistics 932:Statistics for the Social Sciences 631:-value of about 1 in 3.5 million. 627:criterion, which corresponds to a 14: 2725:Antonakis, John (February 2017). 1938:"Confidence Interval or P-Value?" 1738:in Statisticians of the Centuries 16:Concept in inferential statistics 5684: 5672: 5660: 5647: 5646: 3249:Introducing Statistical Methods, 1140:Biostatistics in Clinical Trials 1051:"Statistical Hypothesis Testing" 848: 776:American Statistical Association 638:, significance levels as low as 5322:Least-squares spectral analysis 1383:The Practice of Social Research 778:(ASA) published a statement on 636:genome-wide association studies 5713:Statistical hypothesis testing 4303:Mean-unbiased minimum-variance 3029:Vyse, Stuart (November 2017). 2659:Woolston, Chris (2015-03-05). 2406:Ioannidis, John P. A. (2005). 1016:Introductory Statistics with R 371:Statistical hypothesis testing 21:statistical hypothesis testing 1: 5616:Geographic information system 4832:Simultaneous equations models 3126:10.1080/00031305.2019.1583913 2785:10.1080/00031305.2016.1154108 2700:Siegfried, Tom (2015-03-17). 107:{\displaystyle p\leq \alpha } 4799:Coefficient of determination 4410:Uniformly most powerful test 3196:University of Michigan Press 2746:10.1016/j.leaqua.2017.01.006 2425:10.1371/journal.pmed.0020124 2339:10.1371/journal.pgen.1002812 2213:Bracken, Michael B. (2013). 1833:Hypothesis-testing Behaviour 1740:, Springer, pp. 39–42, 1699:Stigler, Stephen M. (1986). 1537:Postgraduate Medical Journal 1348:Sproull, Natalie L. (2002). 896:Multiple comparisons problem 5368:Proportional hazards models 5312:Spectral density estimation 5294:Vector autoregression (VAR) 4728:Maximum posterior estimator 3960:Randomized controlled trial 3227:10.1016/j.socec.2004.09.034 1942:Deutsches Ärzteblatt Online 1531:Leung, W.-C. (2001-03-01). 1262:Altman, Douglas G. (1999). 1024:10.1007/978-0-387-79054-1_9 595:In specific fields such as 5729: 5128:Multivariate distributions 3548:Average absolute deviation 3326:10.1038/d41586-019-00857-9 3215:Journal of Socio-Economics 3083:10.1038/d41586-019-00857-9 2373:Harvard Educational Review 1800:Fisher, Ronald A. (1925). 906:Texas sharpshooter fallacy 830:{\displaystyle p\leq 0.05} 712: 697: 662: 584: 368: 163: 86:statistically significant, 5642: 5445: 5432: 5116:Structural equation model 5024: 4999: 4770: 4746: 4478: 4452:Score/Lagrange multiplier 4058: 4045: 3867:Sample size determination 3828: 3815: 3445: 3432: 3414: 3206:. Reviews and reception: 3112:The American Statistician 3000:10.1038/s41562-017-0224-0 2973:10.1038/nature.2017.22625 2927:10.1038/s41562-017-0189-z 2771:The American Statistician 2648:. Science-Based Medicine. 2624:www.education.leeds.ac.uk 2592:10.1002/9781118865064.ch5 2077:Healy, Joseph F. (2009). 1954:10.3238/arztebl.2009.0335 1914:10.1017/S030500410001152X 686:between two variables or 387:Type I and type II errors 5611:Environmental statistics 5133:Elliptical distributions 4926:Generalized linear model 4855:Simple linear regression 4625:Hodges–Lehmann estimator 4082:Probability distribution 3991:Stochastic approximation 3553:Coefficient of variation 2959:Chawla, Dalmeet (2017). 2817:10.1177/0013164416668232 2734:The Leadership Quarterly 2102:McKillup, Steve (2006). 1431:McKillup, Steve (2006). 720:Overuse in some journals 241:. They recommended that 150:statistical significance 125:that involves drawing a 25:statistical significance 5271:Cross-correlation (XCF) 4879:Non-standard predictors 4313:Lehmann–ScheffĂ© theorem 3986:Adaptive clinical trial 3251:Sage Publications Ltd, 2876:10.1038/s41562-016-0021 2185:Vaughan, Simon (2013). 1613:John Arbuthnot (1710). 1298:Devore, Jay L. (2011). 1221:Nature Reviews Genetics 1163:Cumming, Geoff (2012). 1106:10.1073/pnas.1313476110 770:Redefining significance 684:correlation coefficient 527:conditional probability 518:{\displaystyle \alpha } 487:{\displaystyle \alpha } 467:{\displaystyle \alpha } 436:{\displaystyle \alpha } 329:{\displaystyle \alpha } 289:{\displaystyle \alpha } 276:The significance level 254:{\displaystyle \alpha } 234:{\displaystyle \alpha } 217:called this cutoff the 48:{\displaystyle \alpha } 5667:Mathematics portal 5488:Engineering statistics 5396:Nelson–Aalen estimator 4973:Analysis of covariance 4860:Ordinary least squares 4784:Pearson product-moment 4188:Statistical functional 4099:Empirical distribution 3932:Controlled experiments 3661:Frequency distribution 3439:Descriptive statistics 3285:Cohen, Joseph (1994). 3233:Chow, Siu L., (1996). 3165:reproducibility crises 2988:Nature Human Behaviour 2914:Nature Human Behaviour 2863:Nature Human Behaviour 2289:10.1038/nprot.2010.182 2135:Health, David (1995). 2023:10.1098/rsta.1937.0005 1637:10.1098/rstl.1710.0011 1549:10.1136/pmj.77.905.201 839: 831: 690:, and other measures. 562:alternative hypothesis 519: 488: 468: 437: 411: 379:Alternative hypothesis 330: 310: 290: 255: 235: 108: 77: 49: 5583:Population statistics 5525:System identification 5259:Autocorrelation (ACF) 5187:Exponential smoothing 5101:Discriminant analysis 5096:Canonical correlation 4960:Partition of variance 4822:Regression validation 4666:(Jonckheere–Terpstra) 4565:Likelihood-ratio test 4254:Frequentist inference 4166:Location–scale family 4087:Sampling distribution 4052:Statistical inference 4019:Cross-sectional study 4006:Observational studies 3965:Randomized experiment 3794:Stem-and-leaf display 3596:Central limit theorem 891:Look-elsewhere effect 873:Estimation statistics 832: 585:Further information: 543:sampling distribution 520: 489: 469: 438: 408:sampling distribution 394: 331: 311: 296:is the threshold for 291: 256: 236: 194:-value § History 166:History of statistics 154:clinical significance 109: 78: 50: 5506:Probabilistic design 5091:Principal components 4934:Exponential families 4886:Nonlinear regression 4865:General linear model 4827:Mixed effects models 4817:Errors and residuals 4794:Confounding variable 4696:Bayesian probability 4674:Van der Waerden test 4664:Ordered alternative 4429:Multiple comparisons 4308:Rao–Blackwellization 4271:Estimating equations 4227:Statistical distance 3945:Factorial experiment 3478:Arithmetic-Geometric 3262:Kline, Rex, (2004). 3208:(compiled by Ziliak) 2162:Statistics explained 1630:(325–336): 186–190. 1350:"Hypothesis testing" 815: 509: 478: 458: 427: 320: 300: 280: 245: 225: 176:Pierre-Simon Laplace 92: 67: 39: 5578:Official statistics 5501:Methods engineering 5182:Seasonal adjustment 4950:Poisson regressions 4870:Bayesian regression 4809:Regression analysis 4789:Partial correlation 4761:Regression analysis 4360:Prediction interval 4355:Likelihood interval 4345:Confidence interval 4337:Interval estimation 4298:Unbiased estimators 4116:Model specification 3996:Up-and-down designs 3684:Partial correlation 3640:Index of dispersion 3558:Interquartile range 3317:2019Natur.567..305A 3247:Volume 1 of series 3145:Scientific American 3074:2019Natur.567..305A 2677:2015Natur.519....9W 2015:1937RSPTA.236..333N 1906:1933PCPS...29..492N 1764:, Wiley, p. 65 1675:Sprent, P. (1989), 1097:2013PNAS..11019313J 1091:(48): 19313–19317. 757:Bayesian statistics 613:normal distribution 591:Normal distribution 494:is also called the 221:, which they named 178:, who computed the 5598:Spatial statistics 5478:Medical statistics 5378:First hitting time 5332:Whittle likelihood 4983:Degrees of freedom 4978:Multivariate ANOVA 4911:Heteroscedasticity 4723:Bayesian estimator 4688:Bayesian inference 4537:Kolmogorov–Smirnov 4422:Randomization test 4392:Testing hypotheses 4365:Tolerance interval 4276:Maximum likelihood 4171:Exponential family 4104:Density estimation 4064:Statistical theory 4024:Natural experiment 3970:Scientific control 3887:Survey methodology 3573:Standard deviation 3362:2022-09-07 at the 3291:2017-07-13 at the 3241:2013-12-03 at the 3189:2010-06-08 at the 2479:10.7717/peerj.3544 1496:"What is P-value?" 1197:10.1038/nmeth.2698 856:Mathematics portal 827: 715:Misuse of p-values 605:standard deviation 587:Standard deviation 525:is set to 5%, the 515: 505:For example, when 496:significance level 484: 464: 433: 412: 326: 306: 286: 251: 231: 219:significance level 137:alone. But if the 104: 73: 45: 33:significance level 5700: 5699: 5638: 5637: 5634: 5633: 5573:National accounts 5543:Actuarial science 5535:Social statistics 5428: 5427: 5424: 5423: 5420: 5419: 5355:Survival function 5340: 5339: 5202:Granger causality 5043:Contingency table 5018:Survival analysis 4995: 4994: 4991: 4990: 4847:Linear regression 4742: 4741: 4738: 4737: 4713:Credible interval 4682: 4681: 4465: 4464: 4281:Method of moments 4150:Parametric family 4111:Statistical model 4041: 4040: 4037: 4036: 3955:Random assignment 3877:Statistical power 3811: 3810: 3807: 3806: 3656:Contingency table 3626: 3625: 3493:Generalized/power 3311:(7748): 305–307. 3257:978-0-7619-5205-3 3204:978-0-472-07007-7 3179:Deirdre McCloskey 3169:scientific fields 3068:(7748): 305–307. 2601:978-1-118-86497-5 2568:978-0-8058-1063-9 2257:978-0-8229-4430-0 2232:978-0-300-18884-4 2196:978-1-107-02482-3 2171:978-1-84872-312-2 2146:978-1-85728-132-3 2121:978-0-521-54316-3 2088:978-0-495-60143-2 2063:978-1-111-34280-7 1878:978-0-521-00976-8 1842:978-1-84169-159-6 1817:978-0-05-002170-5 1786:978-0-415-87968-2 1747:978-0-387-95329-8 1714:978-0-674-40341-3 1686:978-0-412-44980-2 1662:978-0-471-16068-7 1599:978-1-4020-6036-6 1512:on March 31, 2020 1477:978-0-8058-6431-1 1452:978-0-521-54316-3 1417:978-1-4129-3982-9 1392:978-1-133-04979-1 1367:978-0-8108-4486-5 1334:978-1-4129-1611-0 1309:978-0-538-73352-6 1281:978-0-412-27630-9 1190:(11): 1041–1042. 1149:978-0-471-82211-0 1055:www.dartmouth.edu 1033:978-0-387-79053-4 997:978-0-8058-6431-1 969:978-0-87389-745-7 941:978-1-4129-0546-6 749:likelihood ratios 558:research question 309:{\displaystyle p} 76:{\displaystyle p} 5720: 5688: 5687: 5676: 5675: 5665: 5664: 5650: 5649: 5553:Crime statistics 5447: 5434: 5351: 5317:Fourier analysis 5304:Frequency domain 5284: 5231: 5197:Structural break 5157: 5106:Cluster analysis 5053:Log-linear model 5026: 5001: 4942: 4916:Homoscedasticity 4772: 4748: 4667: 4659: 4651: 4650:(Kruskal–Wallis) 4635: 4620: 4575:Cross validation 4560: 4542:Anderson–Darling 4489: 4476: 4447:Likelihood-ratio 4439:Parametric tests 4417:Permutation test 4400:1- & 2-tails 4291:Minimum distance 4263:Point estimation 4259: 4210:Optimal decision 4161: 4060: 4047: 4029:Quasi-experiment 3979:Adaptive designs 3830: 3817: 3694:Rank correlation 3456: 3447: 3434: 3401: 3394: 3387: 3378: 3338: 3328: 3230: 3131: 3130: 3128: 3102: 3096: 3095: 3085: 3053: 3047: 3046: 3044: 3042: 3026: 3020: 3019: 2983: 2977: 2976: 2956: 2950: 2949: 2939: 2929: 2905: 2899: 2898: 2888: 2878: 2853: 2847: 2846: 2836: 2796: 2790: 2789: 2787: 2761: 2750: 2749: 2731: 2722: 2716: 2715: 2713: 2712: 2697: 2691: 2690: 2688: 2656: 2650: 2649: 2641: 2635: 2634: 2632: 2631: 2612: 2606: 2605: 2579: 2573: 2572: 2554: 2548: 2547: 2511: 2502: 2501: 2491: 2481: 2457: 2448: 2447: 2437: 2427: 2403: 2397: 2396: 2368: 2362: 2361: 2351: 2341: 2317: 2311: 2310: 2300: 2277:Nature Protocols 2268: 2262: 2261: 2243: 2237: 2236: 2220: 2210: 2201: 2200: 2182: 2176: 2175: 2157: 2151: 2150: 2132: 2126: 2125: 2109: 2099: 2093: 2092: 2074: 2068: 2067: 2049: 2043: 2042: 2009:(767): 333–380. 1993: 1987: 1982: 1976: 1975: 1965: 1932: 1926: 1925: 1889: 1883: 1882: 1858: 1847: 1846: 1828: 1822: 1821: 1797: 1791: 1790: 1772: 1766: 1765: 1757: 1751: 1750: 1725: 1719: 1718: 1696: 1690: 1689: 1672: 1666: 1665: 1648: 1642: 1641: 1639: 1619: 1610: 1604: 1603: 1585: 1579: 1578: 1568: 1543:(905): 201–204. 1528: 1522: 1521: 1519: 1517: 1511: 1505:. 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statistic 4054: 4033: 4000: 3974: 3926: 3881: 3824: 3822:Data collection 3803: 3715: 3670: 3644: 3622: 3582: 3534: 3451:Continuous data 3441: 3428: 3410: 3405: 3364:Wayback Machine 3345: 3298: 3293:Wayback Machine 3243:Wayback Machine 3212: 3191:Wayback Machine 3175:Ziliak, Stephen 3139: 3137:Further reading 3134: 3104: 3103: 3099: 3055: 3054: 3050: 3040: 3038: 3028: 3027: 3023: 2985: 2984: 2980: 2958: 2957: 2953: 2907: 2906: 2902: 2855: 2854: 2850: 2798: 2797: 2793: 2763: 2762: 2753: 2729: 2724: 2723: 2719: 2710: 2708: 2699: 2698: 2694: 2686:10.1038/519009f 2658: 2657: 2653: 2643: 2642: 2638: 2629: 2627: 2614: 2613: 2609: 2602: 2581: 2580: 2576: 2569: 2556: 2555: 2551: 2513: 2512: 2505: 2459: 2458: 2451: 2405: 2404: 2400: 2370: 2369: 2365: 2332:(7): e1002812. 2319: 2318: 2314: 2270: 2269: 2265: 2258: 2245: 2244: 2240: 2233: 2212: 2211: 2204: 2197: 2184: 2183: 2179: 2172: 2159: 2158: 2154: 2147: 2134: 2133: 2129: 2122: 2101: 2100: 2096: 2089: 2076: 2075: 2071: 2064: 2051: 2050: 2046: 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593: 583: 551:two-tailed test 547:one-tailed test 507: 506: 476: 475: 456: 455: 425: 424: 416:null hypothesis 400: 397:two-tailed test 389: 375:Null hypothesis 369:Main articles: 367: 351: 318: 317: 298: 297: 278: 277: 274: 243: 242: 223: 222: 187:human sex ratio 168: 162: 90: 89: 65: 64: 37: 36: 29:null hypothesis 23:, a result has 17: 12: 11: 5: 5726: 5724: 5716: 5715: 5705: 5704: 5698: 5697: 5695: 5694: 5682: 5670: 5656: 5643: 5640: 5639: 5636: 5635: 5632: 5631: 5629: 5628: 5623: 5618: 5613: 5608: 5602: 5600: 5594: 5593: 5591: 5590: 5585: 5580: 5575: 5570: 5565: 5560: 5555: 5550: 5545: 5539: 5537: 5531: 5530: 5528: 5527: 5522: 5517: 5508: 5503: 5498: 5492: 5490: 5484: 5483: 5481: 5480: 5475: 5470: 5461: 5459:Bioinformatics 5455: 5453: 5443: 5442: 5437: 5430: 5429: 5426: 5425: 5422: 5421: 5418: 5417: 5415: 5414: 5408: 5406: 5402: 5401: 5399: 5398: 5392: 5390: 5384: 5383: 5381: 5380: 5375: 5370: 5365: 5359: 5357: 5348: 5342: 5341: 5338: 5337: 5335: 5334: 5329: 5324: 5319: 5314: 5308: 5306: 5300: 5299: 5297: 5296: 5291: 5286: 5278: 5273: 5268: 5267: 5266: 5264:partial (PACF) 5255: 5253: 5247: 5246: 5244: 5243: 5238: 5233: 5225: 5220: 5214: 5212: 5211:Specific tests 5208: 5207: 5205: 5204: 5199: 5194: 5189: 5184: 5179: 5174: 5169: 5163: 5161: 5154: 5148: 5147: 5145: 5144: 5143: 5142: 5141: 5140: 5125: 5124: 5123: 5113: 5111:Classification 5108: 5103: 5098: 5093: 5088: 5083: 5077: 5075: 5069: 5068: 5066: 5065: 5060: 5058:McNemar's test 5055: 5050: 5045: 5040: 5034: 5032: 5022: 5021: 5004: 4997: 4996: 4993: 4992: 4989: 4988: 4986: 4985: 4980: 4975: 4970: 4964: 4962: 4956: 4955: 4953: 4952: 4936: 4930: 4928: 4922: 4921: 4919: 4918: 4913: 4908: 4903: 4898: 4896:Semiparametric 4893: 4888: 4882: 4880: 4876: 4875: 4873: 4872: 4867: 4862: 4857: 4851: 4849: 4843: 4842: 4840: 4839: 4834: 4829: 4824: 4819: 4813: 4811: 4805: 4804: 4802: 4801: 4796: 4791: 4786: 4780: 4778: 4768: 4767: 4764: 4763: 4758: 4752: 4751: 4744: 4743: 4740: 4739: 4736: 4735: 4733: 4732: 4731: 4730: 4720: 4715: 4710: 4709: 4708: 4703: 4692: 4690: 4684: 4683: 4680: 4679: 4677: 4676: 4671: 4670: 4669: 4661: 4653: 4637: 4634:(Mann–Whitney) 4629: 4628: 4627: 4614: 4613: 4612: 4601: 4599: 4593: 4592: 4590: 4589: 4588: 4587: 4582: 4577: 4567: 4562: 4559:(Shapiro–Wilk) 4554: 4549: 4544: 4539: 4534: 4526: 4520: 4518: 4512: 4511: 4509: 4508: 4500: 4491: 4479: 4473: 4471:Specific tests 4467: 4466: 4463: 4462: 4460: 4459: 4454: 4449: 4443: 4441: 4435: 4434: 4432: 4431: 4426: 4425: 4424: 4414: 4413: 4412: 4402: 4396: 4394: 4388: 4387: 4385: 4384: 4383: 4382: 4377: 4367: 4362: 4357: 4352: 4347: 4341: 4339: 4333: 4332: 4330: 4329: 4324: 4323: 4322: 4317: 4316: 4315: 4310: 4295: 4294: 4293: 4288: 4283: 4278: 4267: 4265: 4256: 4250: 4249: 4247: 4246: 4241: 4236: 4235: 4234: 4224: 4219: 4218: 4217: 4207: 4206: 4205: 4200: 4195: 4185: 4180: 4175: 4174: 4173: 4168: 4163: 4147: 4146: 4145: 4140: 4135: 4125: 4124: 4123: 4118: 4108: 4107: 4106: 4096: 4095: 4094: 4084: 4079: 4074: 4068: 4066: 4056: 4055: 4050: 4043: 4042: 4039: 4038: 4035: 4034: 4032: 4031: 4026: 4021: 4016: 4010: 4008: 4002: 4001: 3999: 3998: 3993: 3988: 3982: 3980: 3976: 3975: 3973: 3972: 3967: 3962: 3957: 3952: 3947: 3942: 3936: 3934: 3928: 3927: 3925: 3924: 3922:Standard error 3919: 3914: 3909: 3908: 3907: 3902: 3891: 3889: 3883: 3882: 3880: 3879: 3874: 3869: 3864: 3859: 3854: 3852:Optimal design 3849: 3844: 3838: 3836: 3826: 3825: 3820: 3813: 3812: 3809: 3808: 3805: 3804: 3802: 3801: 3796: 3791: 3786: 3781: 3776: 3771: 3766: 3761: 3756: 3751: 3746: 3741: 3736: 3731: 3725: 3723: 3717: 3716: 3714: 3713: 3708: 3707: 3706: 3701: 3691: 3686: 3680: 3678: 3672: 3671: 3669: 3668: 3663: 3658: 3652: 3650: 3649:Summary tables 3646: 3645: 3643: 3642: 3636: 3634: 3628: 3627: 3624: 3623: 3621: 3620: 3619: 3618: 3613: 3608: 3598: 3592: 3590: 3584: 3583: 3581: 3580: 3575: 3570: 3565: 3560: 3555: 3550: 3544: 3542: 3536: 3535: 3533: 3532: 3527: 3522: 3521: 3520: 3515: 3510: 3505: 3500: 3495: 3490: 3485: 3483:Contraharmonic 3480: 3475: 3464: 3462: 3453: 3443: 3442: 3437: 3430: 3429: 3427: 3426: 3421: 3415: 3412: 3411: 3406: 3404: 3403: 3396: 3389: 3381: 3375: 3374: 3367: 3353: 3344: 3343:External links 3341: 3340: 3339: 3296: 3283: 3269: 3260: 3231: 3221:(5): 607–613. 3210: 3172: 3138: 3135: 3133: 3132: 3119:(sup1): 1–19. 3097: 3048: 3021: 2978: 2951: 2900: 2848: 2811:(4): 631–662. 2791: 2778:(2): 129–133. 2751: 2717: 2692: 2651: 2636: 2607: 2600: 2574: 2567: 2549: 2503: 2449: 2398: 2379:(3): 378–399. 2363: 2312: 2263: 2256: 2238: 2231: 2202: 2195: 2177: 2170: 2152: 2145: 2127: 2120: 2094: 2087: 2069: 2062: 2044: 1988: 1977: 1927: 1900:(4): 492–510. 1884: 1877: 1848: 1841: 1823: 1816: 1792: 1785: 1767: 1752: 1746: 1720: 1713: 1691: 1685: 1667: 1661: 1643: 1605: 1598: 1580: 1523: 1483: 1476: 1458: 1451: 1423: 1416: 1398: 1391: 1373: 1366: 1340: 1333: 1315: 1308: 1287: 1280: 1254: 1227:(5): 335–346. 1211: 1184:Nature Methods 1170: 1155: 1148: 1130: 1071: 1039: 1032: 1003: 996: 975: 968: 947: 940: 916: 914: 911: 910: 909: 903: 898: 893: 888: 880:for combining 875: 870: 860: 859: 843: 840: 826: 823: 820: 771: 768: 721: 718: 710: 707: 698:Main article: 695: 692: 663:Main article: 660: 657: 651: 648: 582: 579: 514: 483: 463: 432: 366: 363: 338:false positive 325: 305: 285: 273: 270: 250: 230: 172:John Arbuthnot 164:Main article: 161: 158: 135:sampling error 103: 100: 97: 72: 44: 15: 13: 10: 9: 6: 4: 3: 2: 5725: 5714: 5711: 5710: 5708: 5693: 5692: 5683: 5681: 5680: 5671: 5669: 5668: 5663: 5657: 5655: 5654: 5645: 5644: 5641: 5627: 5624: 5622: 5621:Geostatistics 5619: 5617: 5614: 5612: 5609: 5607: 5604: 5603: 5601: 5599: 5595: 5589: 5588:Psychometrics 5586: 5584: 5581: 5579: 5576: 5574: 5571: 5569: 5566: 5564: 5561: 5559: 5556: 5554: 5551: 5549: 5546: 5544: 5541: 5540: 5538: 5536: 5532: 5526: 5523: 5521: 5518: 5516: 5512: 5509: 5507: 5504: 5502: 5499: 5497: 5494: 5493: 5491: 5489: 5485: 5479: 5476: 5474: 5471: 5469: 5465: 5462: 5460: 5457: 5456: 5454: 5452: 5451:Biostatistics 5448: 5444: 5440: 5435: 5431: 5413: 5412:Log-rank test 5410: 5409: 5407: 5403: 5397: 5394: 5393: 5391: 5389: 5385: 5379: 5376: 5374: 5371: 5369: 5366: 5364: 5361: 5360: 5358: 5356: 5352: 5349: 5347: 5343: 5333: 5330: 5328: 5325: 5323: 5320: 5318: 5315: 5313: 5310: 5309: 5307: 5305: 5301: 5295: 5292: 5290: 5287: 5285: 5283:(Box–Jenkins) 5279: 5277: 5274: 5272: 5269: 5265: 5262: 5261: 5260: 5257: 5256: 5254: 5252: 5248: 5242: 5239: 5237: 5236:Durbin–Watson 5234: 5232: 5226: 5224: 5221: 5219: 5218:Dickey–Fuller 5216: 5215: 5213: 5209: 5203: 5200: 5198: 5195: 5193: 5192:Cointegration 5190: 5188: 5185: 5183: 5180: 5178: 5175: 5173: 5170: 5168: 5167:Decomposition 5165: 5164: 5162: 5158: 5155: 5153: 5149: 5139: 5136: 5135: 5134: 5131: 5130: 5129: 5126: 5122: 5119: 5118: 5117: 5114: 5112: 5109: 5107: 5104: 5102: 5099: 5097: 5094: 5092: 5089: 5087: 5084: 5082: 5079: 5078: 5076: 5074: 5070: 5064: 5061: 5059: 5056: 5054: 5051: 5049: 5046: 5044: 5041: 5039: 5038:Cohen's kappa 5036: 5035: 5033: 5031: 5027: 5023: 5019: 5015: 5011: 5007: 5002: 4998: 4984: 4981: 4979: 4976: 4974: 4971: 4969: 4966: 4965: 4963: 4961: 4957: 4951: 4947: 4943: 4937: 4935: 4932: 4931: 4929: 4927: 4923: 4917: 4914: 4912: 4909: 4907: 4904: 4902: 4899: 4897: 4894: 4892: 4891:Nonparametric 4889: 4887: 4884: 4883: 4881: 4877: 4871: 4868: 4866: 4863: 4861: 4858: 4856: 4853: 4852: 4850: 4848: 4844: 4838: 4835: 4833: 4830: 4828: 4825: 4823: 4820: 4818: 4815: 4814: 4812: 4810: 4806: 4800: 4797: 4795: 4792: 4790: 4787: 4785: 4782: 4781: 4779: 4777: 4773: 4769: 4762: 4759: 4757: 4754: 4753: 4749: 4745: 4729: 4726: 4725: 4724: 4721: 4719: 4716: 4714: 4711: 4707: 4704: 4702: 4699: 4698: 4697: 4694: 4693: 4691: 4689: 4685: 4675: 4672: 4668: 4662: 4660: 4654: 4652: 4646: 4645: 4644: 4641: 4640:Nonparametric 4638: 4636: 4630: 4626: 4623: 4622: 4621: 4615: 4611: 4610:Sample median 4608: 4607: 4606: 4603: 4602: 4600: 4598: 4594: 4586: 4583: 4581: 4578: 4576: 4573: 4572: 4571: 4568: 4566: 4563: 4561: 4555: 4553: 4550: 4548: 4545: 4543: 4540: 4538: 4535: 4533: 4531: 4527: 4525: 4522: 4521: 4519: 4517: 4513: 4507: 4505: 4501: 4499: 4497: 4492: 4490: 4485: 4481: 4480: 4477: 4474: 4472: 4468: 4458: 4455: 4453: 4450: 4448: 4445: 4444: 4442: 4440: 4436: 4430: 4427: 4423: 4420: 4419: 4418: 4415: 4411: 4408: 4407: 4406: 4403: 4401: 4398: 4397: 4395: 4393: 4389: 4381: 4378: 4376: 4373: 4372: 4371: 4368: 4366: 4363: 4361: 4358: 4356: 4353: 4351: 4348: 4346: 4343: 4342: 4340: 4338: 4334: 4328: 4325: 4321: 4318: 4314: 4311: 4309: 4306: 4305: 4304: 4301: 4300: 4299: 4296: 4292: 4289: 4287: 4284: 4282: 4279: 4277: 4274: 4273: 4272: 4269: 4268: 4266: 4264: 4260: 4257: 4255: 4251: 4245: 4242: 4240: 4237: 4233: 4230: 4229: 4228: 4225: 4223: 4220: 4216: 4215:loss function 4213: 4212: 4211: 4208: 4204: 4201: 4199: 4196: 4194: 4191: 4190: 4189: 4186: 4184: 4181: 4179: 4176: 4172: 4169: 4167: 4164: 4162: 4156: 4153: 4152: 4151: 4148: 4144: 4141: 4139: 4136: 4134: 4131: 4130: 4129: 4126: 4122: 4119: 4117: 4114: 4113: 4112: 4109: 4105: 4102: 4101: 4100: 4097: 4093: 4090: 4089: 4088: 4085: 4083: 4080: 4078: 4075: 4073: 4070: 4069: 4067: 4065: 4061: 4057: 4053: 4048: 4044: 4030: 4027: 4025: 4022: 4020: 4017: 4015: 4012: 4011: 4009: 4007: 4003: 3997: 3994: 3992: 3989: 3987: 3984: 3983: 3981: 3977: 3971: 3968: 3966: 3963: 3961: 3958: 3956: 3953: 3951: 3948: 3946: 3943: 3941: 3938: 3937: 3935: 3933: 3929: 3923: 3920: 3918: 3917:Questionnaire 3915: 3913: 3910: 3906: 3903: 3901: 3898: 3897: 3896: 3893: 3892: 3890: 3888: 3884: 3878: 3875: 3873: 3870: 3868: 3865: 3863: 3860: 3858: 3855: 3853: 3850: 3848: 3845: 3843: 3840: 3839: 3837: 3835: 3831: 3827: 3823: 3818: 3814: 3800: 3797: 3795: 3792: 3790: 3787: 3785: 3782: 3780: 3777: 3775: 3772: 3770: 3767: 3765: 3762: 3760: 3757: 3755: 3752: 3750: 3747: 3745: 3744:Control chart 3742: 3740: 3737: 3735: 3732: 3730: 3727: 3726: 3724: 3722: 3718: 3712: 3709: 3705: 3702: 3700: 3697: 3696: 3695: 3692: 3690: 3687: 3685: 3682: 3681: 3679: 3677: 3673: 3667: 3664: 3662: 3659: 3657: 3654: 3653: 3651: 3647: 3641: 3638: 3637: 3635: 3633: 3629: 3617: 3614: 3612: 3609: 3607: 3604: 3603: 3602: 3599: 3597: 3594: 3593: 3591: 3589: 3585: 3579: 3576: 3574: 3571: 3569: 3566: 3564: 3561: 3559: 3556: 3554: 3551: 3549: 3546: 3545: 3543: 3541: 3537: 3531: 3528: 3526: 3523: 3519: 3516: 3514: 3511: 3509: 3506: 3504: 3501: 3499: 3496: 3494: 3491: 3489: 3486: 3484: 3481: 3479: 3476: 3474: 3471: 3470: 3469: 3466: 3465: 3463: 3461: 3457: 3454: 3452: 3448: 3444: 3440: 3435: 3431: 3425: 3422: 3420: 3417: 3416: 3413: 3409: 3402: 3397: 3395: 3390: 3388: 3383: 3382: 3379: 3372: 3368: 3365: 3361: 3358: 3354: 3351: 3348:The article " 3347: 3346: 3342: 3336: 3332: 3327: 3322: 3318: 3314: 3310: 3306: 3302: 3297: 3294: 3290: 3287: 3284: 3281: 3277: 3273: 3272:Nuzzo, Regina 3270: 3267: 3266: 3261: 3258: 3254: 3250: 3246: 3244: 3240: 3237: 3232: 3228: 3224: 3220: 3216: 3211: 3209: 3205: 3201: 3197: 3194:. Ann Arbor, 3193: 3192: 3188: 3185: 3180: 3176: 3173: 3170: 3166: 3162: 3158: 3154: 3152: 3147: 3146: 3141: 3140: 3136: 3127: 3122: 3118: 3114: 3113: 3108: 3101: 3098: 3093: 3089: 3084: 3079: 3075: 3071: 3067: 3063: 3059: 3052: 3049: 3036: 3032: 3025: 3022: 3017: 3013: 3009: 3005: 3001: 2997: 2993: 2989: 2982: 2979: 2974: 2970: 2966: 2962: 2955: 2952: 2947: 2943: 2938: 2933: 2928: 2923: 2919: 2915: 2911: 2904: 2901: 2896: 2892: 2887: 2882: 2877: 2872: 2868: 2864: 2860: 2852: 2849: 2844: 2840: 2835: 2830: 2826: 2822: 2818: 2814: 2810: 2806: 2802: 2795: 2792: 2786: 2781: 2777: 2773: 2772: 2767: 2760: 2758: 2756: 2752: 2747: 2743: 2739: 2735: 2728: 2721: 2718: 2707: 2703: 2696: 2693: 2687: 2682: 2678: 2674: 2670: 2666: 2662: 2655: 2652: 2647: 2640: 2637: 2625: 2621: 2619: 2611: 2608: 2603: 2597: 2593: 2589: 2585: 2578: 2575: 2570: 2564: 2560: 2553: 2550: 2545: 2541: 2537: 2533: 2529: 2525: 2521: 2517: 2510: 2508: 2504: 2499: 2495: 2490: 2485: 2480: 2475: 2471: 2467: 2463: 2456: 2454: 2450: 2445: 2441: 2436: 2431: 2426: 2421: 2417: 2413: 2412:PLOS Medicine 2409: 2402: 2399: 2394: 2390: 2386: 2382: 2378: 2374: 2367: 2364: 2359: 2355: 2350: 2345: 2340: 2335: 2331: 2327: 2326:PLOS Genetics 2323: 2316: 2313: 2308: 2304: 2299: 2294: 2290: 2286: 2283:(2): 121–33. 2282: 2278: 2274: 2267: 2264: 2259: 2253: 2249: 2242: 2239: 2234: 2228: 2224: 2219: 2218: 2209: 2207: 2203: 2198: 2192: 2188: 2181: 2178: 2173: 2167: 2163: 2156: 2153: 2148: 2142: 2138: 2131: 2128: 2123: 2117: 2113: 2108: 2107: 2098: 2095: 2090: 2084: 2080: 2073: 2070: 2065: 2059: 2055: 2048: 2045: 2040: 2036: 2032: 2028: 2024: 2020: 2016: 2012: 2008: 2004: 2003: 1998: 1992: 1989: 1986: 1981: 1978: 1973: 1969: 1964: 1959: 1955: 1951: 1948:(19): 335–9. 1947: 1943: 1939: 1931: 1928: 1923: 1919: 1915: 1911: 1907: 1903: 1899: 1895: 1888: 1885: 1880: 1874: 1870: 1866: 1865: 1857: 1855: 1853: 1849: 1844: 1838: 1834: 1827: 1824: 1819: 1813: 1809: 1805: 1804: 1796: 1793: 1788: 1782: 1778: 1771: 1768: 1763: 1756: 1753: 1749: 1743: 1739: 1735: 1731: 1724: 1721: 1716: 1710: 1706: 1702: 1695: 1692: 1688: 1682: 1678: 1671: 1668: 1664: 1658: 1654: 1647: 1644: 1638: 1633: 1629: 1625: 1624: 1616: 1609: 1606: 1601: 1595: 1591: 1584: 1581: 1576: 1572: 1567: 1562: 1558: 1554: 1550: 1546: 1542: 1538: 1534: 1527: 1524: 1508: 1504: 1497: 1490: 1488: 1484: 1479: 1473: 1469: 1462: 1459: 1454: 1448: 1444: 1440: 1435: 1427: 1424: 1419: 1413: 1409: 1402: 1399: 1394: 1388: 1384: 1377: 1374: 1369: 1363: 1359: 1355: 1351: 1344: 1341: 1336: 1330: 1326: 1319: 1316: 1311: 1305: 1301: 1294: 1292: 1288: 1283: 1277: 1273: 1268: 1267: 1258: 1255: 1250: 1246: 1242: 1238: 1234: 1230: 1226: 1222: 1215: 1212: 1207: 1203: 1198: 1193: 1189: 1185: 1181: 1174: 1171: 1166: 1159: 1156: 1151: 1145: 1141: 1134: 1131: 1126: 1122: 1117: 1112: 1107: 1102: 1098: 1094: 1090: 1086: 1082: 1075: 1072: 1061:on 2020-08-02 1060: 1056: 1052: 1046: 1044: 1040: 1035: 1029: 1025: 1021: 1017: 1010: 1008: 1004: 999: 993: 989: 982: 980: 976: 971: 965: 961: 954: 952: 948: 943: 937: 933: 926: 924: 922: 918: 912: 907: 904: 902: 899: 897: 894: 892: 889: 886: 883: 879: 876: 874: 871: 869: 865: 862: 861: 857: 851: 846: 841: 838: 824: 821: 818: 807: 803: 801: 797: 793: 792:data dredging 789: 785: 781: 777: 774:In 2016, the 769: 767: 765: 760: 758: 754: 753:Bayes factors 750: 746: 742: 737: 735: 734: 728: 719: 716: 708: 706: 701: 693: 691: 689: 685: 681: 677: 673: 666: 658: 656: 649: 647: 637: 632: 630: 626: 622: 618: 614: 610: 606: 602: 601:manufacturing 598: 592: 588: 580: 578: 575: 571: 567: 563: 559: 554: 552: 548: 544: 540: 536: 532: 528: 512: 503: 501: 497: 481: 461: 453: 449: 444: 430: 422: 417: 409: 403: 398: 393: 388: 384: 380: 376: 372: 364: 362: 358: 354: 350: 345: 343: 339: 323: 303: 283: 271: 269: 267: 262: 248: 228: 220: 216: 212: 208: 207: 202: 201:Ronald Fisher 197: 196:for details. 195: 193: 188: 184: 182: 177: 173: 167: 159: 157: 155: 151: 147: 142: 140: 136: 132: 128: 124: 120: 115: 101: 98: 95: 87: 83: 70: 62:of a result, 61: 59: 42: 35:, denoted by 34: 30: 26: 22: 5689: 5677: 5658: 5651: 5563:Econometrics 5513: / 5496:Chemometrics 5473:Epidemiology 5466: / 5439:Applications 5281:ARIMA model 5228:Q-statistic 5177:Stationarity 5073:Multivariate 5016: / 5012: / 5010:Multivariate 5008: / 4948: / 4944: / 4718:Bayes factor 4617:Signed rank 4529: 4503: 4495: 4483: 4178:Completeness 4014:Cohort study 3912:Opinion poll 3847:Missing data 3834:Study design 3789:Scatter plot 3711:Scatter plot 3704:Spearman's ρ 3666:Grouped data 3308: 3304: 3279: 3263: 3248: 3234: 3218: 3214: 3182: 3157:experimental 3150: 3143: 3116: 3110: 3100: 3065: 3061: 3051: 3039:. Retrieved 3034: 3024: 2991: 2987: 2981: 2964: 2954: 2937:10281/184094 2917: 2913: 2903: 2866: 2862: 2851: 2808: 2804: 2794: 2775: 2769: 2737: 2733: 2720: 2709:. Retrieved 2706:Science News 2705: 2695: 2668: 2664: 2654: 2639: 2628:. Retrieved 2623: 2617: 2610: 2583: 2577: 2558: 2552: 2522:(3): 241–9. 2519: 2515: 2469: 2465: 2415: 2411: 2401: 2376: 2372: 2366: 2329: 2325: 2315: 2280: 2276: 2266: 2247: 2241: 2216: 2186: 2180: 2161: 2155: 2136: 2130: 2105: 2097: 2078: 2072: 2053: 2047: 2006: 2000: 1991: 1980: 1945: 1941: 1930: 1897: 1893: 1887: 1863: 1832: 1826: 1802: 1795: 1776: 1770: 1761: 1755: 1737: 1723: 1700: 1694: 1676: 1670: 1652: 1646: 1627: 1621: 1608: 1589: 1583: 1540: 1536: 1526: 1516:November 10, 1514:. Retrieved 1507:the original 1502: 1467: 1461: 1438: 1426: 1407: 1401: 1382: 1376: 1353: 1343: 1324: 1318: 1299: 1265: 1257: 1224: 1220: 1214: 1187: 1183: 1173: 1164: 1158: 1139: 1133: 1088: 1084: 1074: 1063:. Retrieved 1059:the original 1054: 1015: 987: 959: 931: 809: 804: 799: 795: 787: 783: 779: 773: 761: 744: 740: 738: 731: 726: 723: 703: 675: 668: 653: 633: 628: 624: 616: 608: 594: 569: 565: 555: 538: 534: 531:type I error 504: 500:type I error 495: 451: 447: 445: 420: 413: 401: 356: 352: 346: 342:type I error 275: 265: 263: 218: 215:Egon Pearson 211:Jerzy Neyman 204: 198: 191: 180: 169: 149: 146:significance 145: 143: 138: 116: 85: 63: 57: 32: 24: 18: 5691:WikiProject 5606:Cartography 5568:Jurimetrics 5520:Reliability 5251:Time domain 5230:(Ljung–Box) 5152:Time-series 5030:Categorical 5014:Time-series 5006:Categorical 4941:(Bernoulli) 4776:Correlation 4756:Correlation 4552:Jarque–Bera 4524:Chi-squared 4286:M-estimator 4239:Asymptotics 4183:Sufficiency 3950:Interaction 3862:Replication 3842:Effect size 3799:Violin plot 3779:Radar chart 3759:Forest plot 3749:Correlogram 3699:Kendall's τ 2994:(1): 0224. 2920:(1): 6–10. 2869:(1): 0021. 2740:(1): 5–21. 2671:(7541): 9. 2418:(8): e124. 901:Sample size 882:independent 864:A/B testing 764:metascience 674:along with 672:effect size 665:Effect size 659:Effect size 650:Limitations 621:Higgs boson 123:observation 5558:Demography 5276:ARMA model 5081:Regression 4658:(Friedman) 4619:(Wilcoxon) 4557:Normality 4547:Lilliefors 4494:Student's 4370:Resampling 4244:Robustness 4232:divergence 4222:Efficiency 4160:(monotone) 4155:Likelihood 4072:Population 3905:Stratified 3857:Population 3676:Dependence 3632:Count data 3563:Percentile 3540:Dispersion 3473:Arithmetic 3408:Statistics 3035:csicop.org 2711:2016-12-01 2630:2016-12-01 2586:: 87–114. 1997:Neyman, J. 1730:C.C. Heyde 1065:2019-11-11 913:References 713:See also: 709:Challenges 688:its square 607:or sigma ( 131:population 119:experiment 4939:Logistic 4706:posterior 4632:Rank sum 4380:Jackknife 4375:Bootstrap 4193:Bootstrap 4128:Parameter 4077:Statistic 3872:Statistic 3784:Run chart 3769:Pie chart 3764:Histogram 3754:Fan chart 3729:Bar chart 3611:L-moments 3498:Geometric 3161:certainty 2825:0013-1644 2472:: e3544. 1922:119855116 1734:E. Seneta 1557:0032-5473 822:≤ 680:Cohen's d 513:α 482:α 462:α 431:α 324:α 284:α 249:α 229:α 199:In 1925, 102:α 99:≤ 43:α 5707:Category 5653:Category 5346:Survival 5223:Johansen 4946:Binomial 4901:Isotonic 4488:(normal) 4133:location 3940:Blocking 3895:Sampling 3774:Q–Q plot 3739:Box plot 3721:Graphics 3616:Skewness 3606:Kurtosis 3578:Variance 3508:Heronian 3503:Harmonic 3360:Archived 3335:30894741 3289:Archived 3274:(2014). 3239:Archived 3198:, 2009. 3187:Archived 3181:(2008), 3167:in many 3092:30894741 3016:46814177 3008:30980046 2946:30980045 2895:33954258 2843:30034024 2536:15316274 2498:28698825 2444:16060722 2393:16355113 2358:22792080 2307:21293453 2039:19584450 1972:19547734 1736:(eds.), 1575:11222834 1249:10961123 1241:24739678 1206:24344377 1125:24218581 868:ABX test 842:See also 755:. 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Index

statistical hypothesis testing
null hypothesis
p-value
experiment
observation
sample
population
sampling error
clinical significance
History of statistics
John Arbuthnot
Pierre-Simon Laplace
p-value
human sex ratio
p-value § History
Ronald Fisher
Statistical Methods for Research Workers
Jerzy Neyman
Egon Pearson
false positive
type I error
confidence level
Statistical hypothesis testing
Null hypothesis
Alternative hypothesis
p-value
Type I and type II errors

two-tailed test
sampling distribution

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