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Cole was scientific coordinator for the New
Medicines For Tuberculosis project (NM4TB), running from 2006 to 2009 and the ensuing More Medicines For Tuberculosis project (MM4TB) running from 2011 to 2016 in the context of the FP7 European Union's Research and Innovation funding programme. This work
320:
on 13 October 2017, 130 years after its foundation, thus becoming the first non-French appointee. He took office on 2 January 2018, when he began to prepare the institute's
Strategic Plan for 2019–2023. The overarching ambition of the Strategic Plan was to give new impetus to basic research at the
220:
have been widely acclaimed and are of direct relevance to global health and disease-control in both the developing world and the industrialized nations. Over four decades his team has investigated a range of topics including: bacterial electron transport systems; the genomics and diagnostics of
172:
Cole grew up in Wales, where he was educated at
Milford Haven Grammar School and then at Ardwyn Grammar School, Aberystwyth. Following a life-threatening bout of paratyphoid he developed an interest in bacteria, viruses and infectious diseases, which led to his reading microbiology at the
674:
Makarov, Vadim; Lechartier, Benoit; Zhang, Ming; Neres, João; Sar, Astrid M; Raadsen, Susanne A; Hartkoorn, Ruben C; Ryabova, Olga B; Vocat, Anthony; Decosterd, Laurent A; Widmer, Nicolas; Buclin, Thierry; Bitter, Wilbert; Andries, Koen; Pojer, Florence (March 2014).
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In 2014, EPFL mandated its spin-off iM4TB, (Innovative
Medicines for Tuberculosis ) a not-for-profit foundation, to raise funds and undertake preclinical development of PBTZ169. This was achieved with support from EPFL and the
280:
Cole is also an inventor on many patents, several of which were licensed to industrial partners giving rise to diagnostic and therapeutic products that have found direct application in human medicine and helped save lives.
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Cole has supervised numerous students for MS and PhD degrees, and trained >50 postdoctoral fellows and clinicians. With them, he has published over 400 scientific papers and review articles. Notable alumni include
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205:(EPFL, one of the two Swiss Federal Institutes of Technology). His laboratory at EPFL closed in December 2018. He was previously professor, senior vice president and scientific director of the
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for his institute - research, public health, training/education and translating research into applications of value to humanity - are as relevant today as they were in 1887 when the
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research and global health for many years. Between 2007 and 2017, he was a full professor and director of the Global Health
Institute at the
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880:"Sir Stewart Cole joins the Ineos Oxford Institute for antimicrobial research as Executive Chair | University of Oxford"
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institute and to increase its impact on human health. Priority areas of the
Strategic Plan included (re)
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led to the discovery of the TB drug candidate BTZ043 and PBTZ169 based on the benzothiazinone scaffold.
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is developing new treatment regimens for TB and receives funding from the
European Commission's IMI
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293:. Both BTZ043 and PBTZ169 completed phase 1 clinical trials and then entered phase 2a trials.
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on antimicrobial research as
Executive Chair and became President of the Pasteur Foundation - UK.
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677:"Towards a new combination therapy for tuberculosis with next generation benzothiazinones"
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In 2019, Cole was appointed academic
Scientific leader of the public-private initiative
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333:. From the Strategic Plan it is clear that the four missions originally defined by
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536:"Stewart Cole Inventions, Patents and Patent Applications - Justia Patents Search"
619:"Benzothiazinones Kill Mycobacterium tuberculosis by Blocking Arabinan Synthesis"
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758:"Search of: PBTZ169 | Tuberculosis - List Results - ClinicalTrials.gov"
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733:"Search of: BTZ043 | Tuberculosis - List Results - ClinicalTrials.gov"
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828:"Professor Stewart Cole appointed President of the Institut Pasteur"
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Stewart Cole was appointed as the 16th director general of the
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from the article and its talk page, especially if potentially
21:
438:
2016: Gardner
Middlebrook Award, 37th Annual Congress of the
181:, England. Subsequently, he was a postdoctoral fellow at the
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213:(1983 – 2007), which he later rejoined as Director General.
1542:
Knights Commander of the Order of St Michael and St George
1039:"Stewart Cole receives the Gardner Middlebrook Award 2016"
455:
Knight Commander of the Order of St Michael and St George
353:
Knight Commander of the Order of St Michael and St George
595:
341:
was founded. He completed his term on 31 December 2023.
233:
mechanisms; and the molecular microbiology of toxigenic
814:"Stewart Cole appointed president of Institut Pasteur"
301:
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492:"UPCOL – Cole Lab – Chair of Microbial Pathogenesis"
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1422:
1179:
1129:UPCOL - Cole Lab - Chair of Microbial Pathogenesis
962:. Society for General Microbiology. Archived from
300:(European Regimen Accelerator for Tuberculosis).
432:2014: Ass. Member National Academy of Pharmacy,
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8:
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1142:
1134:
59:about living persons that is unsourced or
948:(Supplement). 1 January 2022. p. N3.
708:
650:
185:(Sweden) and a research assistant at the
130:Learn how and when to remove this message
203:École polytechnique fédérale de Lausanne
1522:People educated at Milford Haven School
483:
1012:"Warm congratulations to Stewart Cole"
1527:Alumni of the University of Sheffield
1045:from the original on 16 February 2017
1018:from the original on 16 February 2017
834:from the original on 18 November 2021
812:Papageorgiou, Nik (23 October 2017).
546:from the original on 29 February 2024
164:since January 2018 to December 2023.
160:. He was the Director General of the
7:
463:of Medicine, University of Sheffield
440:European Society of Mycobacteriology
1037:Papageorgiou, Nik (8 August 2016).
787:IMI Innovative Medicines Initiative
395:2004: Chevalier in the Ordre de la
291:Bill & Melinda Gates Foundation
992:from the original on 30 March 2017
960:"Marjory Stephenson Prize Lecture"
466:2024: Officier in the Ordre de la
14:
1512:Alumni of the University of Wales
986:"2009 Kochon Prize Award Winners"
890:from the original on 2 March 2024
793:from the original on 19 June 2024
592:"More Medicines For Tuberculosis"
312:Director of the Pasteur Institute
920:from the original on 6 June 2024
617:Makarov, Vadim (14 March 2009).
566:"New Medicines For Tuberculosis"
516:from the original on 26 May 2024
388:Society for General Microbiology
216:His research accomplishments in
197:Stewart Cole has been active in
156:(born 1955) is a British/French
26:
187:Max-Planck-Institut for Biology
854:"Strategic plan for 2019-2023"
1:
1507:Fellows of the Royal Society
415:2009: Kochon Prize from the
323:emerging infectious diseases
37:biography of a living person
64:must be removed immediately
1558:
762:classic.clinicaltrials.gov
737:classic.clinicaltrials.gov
331:neurodegenerative diseases
15:
1517:People from Milford Haven
910:"Pasteur Foundation - UK"
417:World Health Organization
359:for services to science.
329:, brain connectivity and
1100:"Steward Cole Interview"
384:Marjory Stephenson Prize
327:antimicrobial resistance
306:Antimicrobial Resistance
168:Early life and education
1502:British microbiologists
1334:Robert Mair, Baron Mair
988:. STOP-TB Partnership.
681:EMBO Molecular Medicine
643:10.1126/science.1171583
419:'s STOP-TB Partnership
370:Prix Jean-Pierre Lecocq
363:Awards and distinctions
179:University of Sheffield
145:Sir Stewart Thomas Cole
1397:Veronica van Heyningen
1014:. EPFL. 11 June 2014.
693:10.1002/emmm.201303575
346:Ineos Oxford Institute
189:, Tübingen (Germany).
51:Please help by adding
428:University of Marburg
374:Académie des Sciences
357:2022 New Year Honours
231:antibiotic resistance
1450:Jeremiah P. Ostriker
1387:David C. Sherrington
1365:Edward Arend Perkins
914:pasteurfoundation.uk
478:Notes and references
405:2007: Fellow of the
225:(HIV) and oncogenic
57:Contentious material
18:Kenneth Stewart Cole
1124:on 24 January 2011.
1064:sam (1 July 2023).
830:. 13 October 2017.
635:2009Sci...324..801M
344:In 2024 joined the
308:(AMR) Accelerator.
193:Career and research
175:University of Wales
1254:George F. R. Ellis
1112:"Cole, Stewart T."
1066:"Honorary degrees"
966:on 10 January 2015
945:The London Gazette
886:. 9 January 2024.
540:patents.justia.com
510:scholar.google.com
199:infectious disease
183:University of Umeå
1489:
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1329:Ravinder N. Maini
1094:Pasteur Institute
629:(5928): 801–804.
598:on 9 October 2018
572:on 9 October 2018
392:2002: EMBO member
351:He was appointed
339:Pasteur Institute
318:Pasteur Institute
207:Pasteur Institute
162:Pasteur Institute
140:
139:
132:
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40:needs additional
1549:
1455:Michael O. Rabin
1430:Wallace Broecker
1414:Andrew Zisserman
1324:Peter Littlewood
1294:Anthony A. Hyman
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1117:. Archived from
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568:. Archived from
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468:Légion d’Honneur
424:Emil von Behring
397:Légion d’Honneur
255:Priscille Brodin
227:papillomaviruses
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53:reliable sources
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1314:Ottoline Leyser
1299:Anthony Kinloch
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1249:George Coupland
1238:Richard Cogdell
1202:Samuel Berkovic
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1106:on 4 June 2011.
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1070:Your University
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506:"Stewart Cole"
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1119:the original
1104:the original
1073:. Retrieved
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884:www.ox.ac.uk
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239:tuberculosis
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46:verification
39:
1537:1955 births
1445:Tom Fenchel
1392:Terence Tao
1319:Paul Linden
1284:Bill Harris
1222:Peter Bruce
1217:David Boger
1075:29 February
1049:15 February
1022:15 February
970:15 February
940:"No. 63571"
924:29 February
894:29 February
864:29 February
797:29 February
767:29 February
742:29 February
602:15 February
576:15 February
550:29 February
520:8 September
275:Tim Stinear
1496:Categories
1264:Andre Geim
783:"Homepage"
235:clostridia
90:newspapers
16:See also:
1187:Brad Amos
701:1757-4676
386:from the
42:citations
1474:Honorary
1171:elected
1043:Archived
1041:. EPFL.
1016:Archived
996:29 March
990:Archived
918:Archived
888:Archived
832:Archived
791:Archived
719:24500695
661:19299584
544:Archived
514:Archived
68:libelous
1423:Foreign
1180:Fellows
1173:in 2007
1167:of the
1165:Fellows
838:16 July
710:3958311
652:3128490
631:Bibcode
623:Science
444:Catania
243:leprosy
229:(HPV);
104:scholar
717:
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472:France
459:2023:
453:2022:
434:France
422:2014:
401:France
382:2002:
378:France
368:2001:
302:ERA4TB
298:ERA4TB
241:(TB),
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1122:(PDF)
1115:(PDF)
448:Italy
211:Paris
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111:JSTOR
97:books
35:This
1077:2024
1051:2017
1024:2017
998:2017
972:2017
926:2024
896:2024
866:2024
840:2018
799:2024
769:2024
744:2024
715:PMID
697:ISSN
657:PMID
604:2017
578:2017
552:2024
522:2022
273:and
245:and
149:KCMG
83:news
44:for
705:PMC
689:doi
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639:doi
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