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in the treatment of intractable depression. Preliminary results suggest significant improvement with modulation of the DDCS through SM stimulation. Given the intertwined nature of the SM and habenula, it is challenging to define a function for the SM independent of the habenula.
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Roddy, Darren W.; Roman, Elena; Rooney, Shane; Andrews, Sinaoife; Farrell, Chloe; Doolin, Kelly; Levins, Kirk J.; Tozzi, Leonardo; Tierney, Paul; Barry, Denis; Frodl, Thomas; O’Keane, Veronica; O’Hanlon, Erik (2018).
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areas, and conveys information to the lateral and medial habenulae. It operates in a predominantly unidirectional manner, transmitting input from forebrain regions to the habenula. The SM's afferents are primarily
433:"Awakening Neuropsychiatric Research Into the Stria Medullaris: Development of a Diffusion-Weighted Imaging Tractography Protocol of This Key Limbic Structure"
326:
Roman, Elena; Weininger, Joshua; Lim, Basil; Roman, Marin; Barry, Denis; Tierney, Paul; O’Hanlon, Erik; Levins, Kirk; O’Keane, Veronica; Roddy, Darren (2020).
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328:"Untangling the dorsal diencephalic conduction system: a review of structure and function of the stria medullaris, habenula and fasciculus retroflexus"
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Juárez-Leal, Iris; Carretero-RodrĂguez, EstefanĂa; Almagro-GarcĂa, Francisca; MartĂnez, Salvador; EchevarrĂa, Diego; Puelles, Eduardo (2022).
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303:. Bilateral transection of the SM in rodents causes decreases of enzymes in the habenulae, indicating functional importance there.
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246:. As it courses caudally along the third ventricle's roof, it attaches to the tela chordae and arches dorsally over the
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262:'s base, crossing to the opposite side and terminating in the contralateral habenula. This crossing is known as the
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206:. It first received its present name from Wenzel and Wenzel in 1812. The SM can be referred to as the
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The SM, in conjunction with the habenula, has been identified as a potential therapeutic target for
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on the border between dorsal and medial surfaces of thalamus. The SM, in conjunction with the
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377:"Stria medullaris innervation follows the transcriptomic division of the habenula"
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254:. The SM then descends caudally, with its lateral fibers terminating in the
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The SM primarily gathers fibers from various brain regions, including the
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and forms a bilateral white matter tract of the initial segment of the
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The SM emerges as a bilateral compact fascicle just posterior to the
258:. The medial SM fibers, on the other hand, flex inwards towards the
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250:. In the majority of individuals, it arches superior to the
226:. It was once thought to be part of the olfactory system.
191:. It is considered to be the primary afferent of the DDCS.
179:. It forms a horizontal ridge on the medial surface of the
151:(SM), (Latin, furrow and pith or marrow) is a part of the
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38:to the thalamus, the highlighted portion is the
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30:Stria medullaris highlighted in red over the
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214:. Historically it has also been called the
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950:Posterior (sympathetic/heat conservation)
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187:and the habenular commissure, forms the
204:De Humani Corporis Fabrica Libri Septem
134:
15:
157:dorsal diencephalic conduction system
7:
945:Anterior (parasympathetic/heat loss)
14:
984:Parvocellular neurosecretory cell
979:Magnocellular neurosecretory cell
867:Anterior trigeminothalamic tract
131:Anatomical terms of neuroanatomy
1104:Dorsal longitudinal fasciculus
238:, where it converges with the
1:
620:Stria medullaris of thalamus
332:Brain Structure and Function
19:Stria medullaris of thalamus
1022:Suprachiasmatic (melatonin)
1525:
1453:Anterior olfactory nucleus
625:Thalamic reticular nucleus
394:10.1038/s41598-022-14328-1
344:10.1007/s00429-020-02069-8
63:stria medullaris thalamica
1314:
437:Frontiers in Neuroanatomy
129:
23:
1317:Primary olfactory cortex
1161:Nuclei campi perizonalis
1087:Retinohypothalamic tract
450:10.3389/fnana.2018.00039
208:stria medullaris thalami
173:anterior thalamic nuclei
1427:Medial forebrain bundle
1325:Lateral olfactory stria
1308:areas involved in smell
1082:Medial forebrain bundle
1012:Arcuate (dopamine/GHRH)
1483:Evolution of olfaction
1445:Medial olfactory stria
1099:Mammillothalamic tract
862:Subthalamic fasciculus
796:Pallidothalamic tracts
791:Mammillothalamic tract
773:Interthalamic adhesion
313:deep brain stimulation
252:interthalamic adhesion
202:showed it in his 1543
1367:Periamygdaloid cortex
1355:Hippocampal formation
1345:EC-hippocampus system
1126:is diencephalon, but
847:Dentatothalamic tract
806:Lenticular fasciculus
768:Midline nuclear group
307:Clinical significance
830:Trigeminal lemniscus
591:Subcommissural organ
563:Habenular commissure
264:habenular commissure
167:, lateral preoptico-
159:(DDCS). It contains
1151:Subthalamic nucleus
969:posterior pituitary
837:Spinothalamic tract
811:Thalamic fasciculus
236:anterior commissure
1262:Olfactory receptor
1239:Sustentacular cell
852:Acoustic radiation
381:Scientific Reports
216:columna medullaris
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1350:Entorhinal cortex
1296:Olfactory trigone
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1137:
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882:
881:
874:Medullary laminae
842:Lateral lemniscus
801:Ansa lenticularis
599:
598:
558:Habenular trigone
220:markiger Streisen
189:habenular trigone
145:
144:
140:
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1478:Olfactory system
1407:Stria terminalis
1387:Habenular nuclei
1383:Stria medullaris
1362:Prepyriform area
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1077:Stria terminalis
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825:Medial lemniscus
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586:Habenular nuclei
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338:(5): 1437–1458.
244:stria terminalis
163:fibers from the
149:stria medullaris
137:edit on Wikidata
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1340:Piriform cortex
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1291:Olfactory tract
1254:Olfactory nerve
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1165:Fields of Forel
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1017:Preoptic (GnRH)
974:Paraventricular
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912:Mammillary body
903:Median eminence
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857:Optic radiation
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705:Pulvinar nuclei
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519:Anatomy of the
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297:glutamatergic
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165:septal nuclei
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1431:Hypothalamus
1411:Hypothalamus
1382:
1284:mitral cells
1215:Microanatomy
1156:Zona incerta
1130:is glandular
1093:
1071:
1064:White matter
1045:Ventromedial
1008:
967:
917:Infundibulum
888:Hypothalamus
817:
783:White matter
761:Centromedian
756:Intralaminar
747:
712:Metathalamus
652:
619:
548:Pineal gland
521:diencephalon
440:
436:
387:(1): 10118.
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288:hypothalamic
273:
260:pineal gland
233:
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171:region, and
169:hypothalamic
148:
146:
100:A14.1.08.106
88:birnlex_1066
62:
40:pineal gland
1504:Epithalamus
1244:Tufted cell
1143:Subthalamus
1050:Dorsomedial
1000:vasopressin
927:Grey matter
640:Grey matter
573:Grey matter
533:Epithalamus
525:human brain
293:cholinergic
153:epithalamus
52:Identifiers
1498:Categories
1222:Epithelium
991:Supraoptic
485:References
70:NeuroNames
1279:glomeruli
1124:Posterior
1116:Pituitary
960:Endocrine
936:Autonomic
459:1662-5129
403:2045-2322
368:218495735
352:1863-2653
301:GABAergic
36:Posterior
1509:Thalamus
1403:Amygdala
1128:anterior
1094:efferent
1072:afferent
996:oxytocin
748:midline:
605:Thalamus
553:Habenula
477:29867378
421:35710872
360:32367265
284:striatal
270:Function
256:habenula
248:thalamus
200:Vesalius
185:habenula
181:thalamus
177:habenula
161:afferent
82:NeuroLex
32:thalamus
1466:General
1040:Lateral
1032:Emotion
896:Surface
690:Lateral
661:Ventral
653:paired:
613:Surface
541:Surface
523:of the
468:5952041
412:9203815
320:Sources
276:frontal
230:Anatomy
195:History
175:to the
47:Details
1267:neuron
1232:mucosa
1227:glands
1009:other:
737:K cell
732:M cell
727:P cell
645:nuclei
475:
465:
457:
443:: 39.
419:
409:
401:
366:
358:
350:
299:, and
286:, and
280:septal
240:fornix
1306:Brain
1208:Smell
938:zones
364:S2CID
135:[
124:62080
58:Latin
1473:Odor
819:PCML
473:PMID
455:ISSN
417:PMID
399:ISSN
356:PMID
348:ISSN
242:and
224:rené
222:and
147:The
112:5747
95:TA98
683:VPL
679:VPM
463:PMC
445:doi
407:PMC
389:doi
340:doi
336:225
266:.
210:or
119:FMA
107:TA2
75:298
1500::
1429:→
1409:→
1405:→
1385:→
751:MD
722:LG
717:MG
700:LP
695:LD
675:VP
670:VL
666:VA
656:AN
471:.
461:.
453:.
441:12
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