47:
695:
Tognetti, Linda; Filippou, Georgios; Bertrando, Sara; Picerno, Valentina; Buonocore, Giuseppe; Frediani, Bruno; Fimiani, Michele; Rubegni, Pietro (December 10, 2014). "Subcutaneous Fat
Necrosis in a Newborn after Brief Therapeutic Hypothermia: Ultrasonographic Examination".
986:
409:
Mahé, E.; Girszyn, N.; Hadj-Rabia, S.; Bodemer, C.; Hamel-Teillac, D.; De Prost, Y. (2007). "Subcutaneous fat necrosis of the newborn: a systematic evaluation of risk factors, clinical manifestations, complications and outcome of 16 children".
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to violaceous nodules on the cheeks, back, buttocks, or proximal extremities. Usually, the abdomen and chest are unaffected. There has been a case report of SCFN with localized scalp
1946:
464:
Stefanko, Nicole S.; Drolet, Beth A. (September 6, 2018). "Subcutaneous fat necrosis of the newborn and associated hypercalcemia: A systematic review of the literature".
71:, though the exact cause is unknown. It has been suggested that the brown fat seen in newborns is more sensitive to hypoxic injury than fat seen in adults, and that such
660:
Fajgenbaum, Kristen; Zeitany, Alexandra; Googe, Paul B.; Morrell, Dean S.; McShane, Diana (July 9, 2018). "Firm, Indurated
Plaques After Therapeutic Hypothermia".
358:
Xu, Ziyang; Rubin, Adam I.; Oboite, Michelle (June 18, 2021). "Subcutaneous fat necrosis of the newborn presenting as circular alopecia: a novel presentation".
1360:
1976:
1826:
1677:
1375:
1365:
794:
Mitra, Subhabrata; Dove, Jennifer; Somisetty, Sateesh Kumar (2011-02-12). "Subcutaneous fat necrosis in newborn—an unusual case and review of literature".
751:
Lara, Leire González; Villa, Asunción
Vicente; Rivas, MarĂa Mercedes Otero; Capella, Mariona Sunol; Prada, Fredy; Enseñat, MarĂa Antonia González (2017).
550:
Tran, Julie Thao; Sheth, Anita P. (2003). "Complications of
Subcutaneous Fat Necrosis of the Newborn: A Case Report and Review of the Literature".
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Subcutaneous fat necrosis of the newborn (SCFN) occurs in full-term newborns usually in the first six weeks of life as indurated plaques or
1936:
1258:
1725:
1885:
1263:
507:
Del Pozzo-Magaña, Blanca R.; Ho, Nhung (August 30, 2016). "Subcutaneous Fat
Necrosis of the Newborn: A 20-Year Retrospective Study".
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occurring in newborns that is usually self-remitting and non-recurring. Proposed causes include perinatal stress, local trauma,
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162:
Although the exact cause of the newborn's subcutaneous fat necrosis is unknown, several systemic maternal diseases, including
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and the clinical presentation must both be taken into account for the most accurate diagnosis. But in order to prevent
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1411:
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1416:
1406:
1297:
240:
Matar, Marla M. (2021). "A Case Report and
Anesthetic Considerations in Subcutaneous Fat Necrosis of the Newborn".
202:
examination has been shown to be useful in identifying the newborn's subcutaneous fat necrosis when combined with
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75:, usually in the context of a complicated birth, leads to the fat necrosis. Complications can include
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603:"Severe Thrombocytosis in a Newborn with Subcutaneous Fat Necrosis and Maternal Chorioamnionitis"
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206:; this usually indicates a subcutaneous high echo signal, either with or without calcifications.
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About 50% of newborns with subcutaneous fat necrosis of the newborn (SCFN) experience
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182:, and obstetric trauma, may act as precipitating factors in the development of SCFN.
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134:, a potentially fatal consequence. Some infants with SCFN experience
952:
601:
Sahni, Mitali; Patel, Pooja; Muthukumar, Akila (February 22, 2020).
1441:
1188:
919:
308:
Rapini, Ronald P.; Bolognia, Jean L.; Jorizzo, Joseph L. (2007).
753:"Subcutaneous Fat Necrosis of the Newborn: Report of Five Cases"
1666:
968:
283:
James, William D.; Berger, Timothy G.; et al. (2006).
107:, and can present months after the onset of SCFN symptoms.
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457:
802:(9). Springer Science and Business Media LLC: 1107–1110.
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418:(4). Oxford University Press (OUP): 709–715.
8:
1827:Alpha-1 antitrypsin deficiency panniculitis
1947:Marfanoid–progeroid–lipodystrophy syndrome
1872:
1707:
1685:
1671:
1663:
1241:
1015:
987:
973:
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45:
18:
768:
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1760:Subcutaneous fat necrosis of the newborn
57:Subcutaneous fat necrosis of the newborn
22:Subcutaneous fat necrosis of the newborn
232:
7:
1937:Congenital generalized lipodystrophy
1259:Infant respiratory distress syndrome
668:(12). SAGE Publications: 1468–1471.
127:. Tenderness is common in lesions.
1977:Conditions of the subcutaneous fat
1886:Acquired generalized lipodystrophy
1264:Transient tachypnea of the newborn
14:
1042:Twin-to-twin transfusion syndrome
1787:Lupus erythematosus panniculitis
1560:Vertically transmitted infection
564:10.1046/j.1525-1470.2003.20315.x
424:10.1111/j.1365-2133.2007.07782.x
1652:Fetal Alcohol Spectrum Disorder
1602:Group B streptococcal infection
1170:Intrauterine growth restriction
1942:Familial partial lipodystrophy
1896:Acquired partial lipodystrophy
995:Conditions originating in the
796:European Journal of Pediatrics
412:British Journal of Dermatology
154:is seen in infants with SCFN.
1:
1344:Vitamin K deficiency bleeding
1906:HIV-associated lipodystrophy
1854:Superficial thrombophlebitis
1503:Periventricular leukomalacia
1321:Persistent fetal circulation
1269:Meconium aspiration syndrome
770:10.1016/j.pedneo.2014.06.010
757:Pediatrics & Neonatology
254:10.1213/XAA.0000000000001422
1412:Intraventricular hemorrhage
204:Doppler blood flow analysis
1993:
1417:Germinal matrix hemorrhage
1407:Velamentous cord insertion
1298:Bronchopulmonary dysplasia
607:Case Reports in Hematology
59:is a rare form of lobular
1901:Centrifugal lipodystrophy
1770:Post-steroid panniculitis
1447:Necrotizing enterocolitis
1156:Large for gestational age
1152:Small for gestational age
808:10.1007/s00431-011-1405-x
763:(1). Elsevier BV: 85–88.
310:Dermatology: 2-Volume Set
123:covering an erythematous
1792:Sclerosing lipogranuloma
674:10.1177/0009922818785992
613:. Hindawi Limited: 1–3.
1921:Localized lipodystrophy
1782:Weber–Christian disease
1609:Neonatal conjunctivitis
1100:Single umbilical artery
1090:Umbilical cord prolapse
1037:Placental insufficiency
1010:complicating pregnancy,
216:Pancreatic panniculitis
1911:Lipoatrophia annularis
1726:Cytophagic histiocytic
1585:ureaplasma urealyticum
1293:Wilson–Mikity syndrome
1217:Brachial plexus injury
148:elevated triglycerides
1533:Congenital hypertonia
1424:Anemia of prematurity
1132:Shoulder presentation
704:(3). Wiley: 427–429.
698:Pediatric Dermatology
558:(3). Wiley: 257–261.
552:Pediatric Dermatology
509:Pediatric Dermatology
466:Pediatric Dermatology
366:(4). Wiley: 982–983.
360:Pediatric Dermatology
287:. Saunders Elsevier.
1777:Lipodermatosclerosis
1755:needle-shaped clefts
1538:Congenital hypotonia
1452:Meconium peritonitis
1254:Intrauterine hypoxia
1210:Subgaleal hemorrhage
620:10.1155/2020/5742394
312:. St. Louis: Mosby.
1824:without vasculitis:
1765:Sclerema neonatorum
1717:without vasculitis
1647:Neonatal withdrawal
1630:Perinatal mortality
1480:Sclerema neonatorum
1336:hematologic disease
662:Clinical Pediatrics
472:(1). Wiley: 24–30.
180:meconium aspiration
1806:Erythema induratum
1802:Nodular vasculitis
1580:mycoplasma hominis
1565:Neonatal infection
1521:Gray baby syndrome
1498:Perinatal asphyxia
1388:Hyperbilirubinemia
1165:Postterm pregnancy
1012:labour or delivery
930:External resources
111:Signs and symptoms
1964:
1963:
1960:
1959:
1862:
1861:
1660:
1659:
1548:
1547:
1398:Neonatal jaundice
1316:Pneumopericardium
1286:Pneumomediastinum
1227:Klumpke paralysis
1205:Caput succedaneum
1140:
1139:
1008:Maternal factors
962:
961:
710:10.1111/pde.12454
521:10.1111/pde.12973
478:10.1111/pde.13640
372:10.1111/pde.14664
319:978-1-4160-2999-1
294:978-0-7216-2921-6
54:
53:
16:Medical condition
1984:
1873:
1851:with vasculitis:
1832:Erythema nodosum
1799:with vasculitis:
1708:
1695:subcutaneous fat
1687:
1680:
1673:
1664:
1640:Infant mortality
1475:Erythema toxicum
1467:thermoregulation
1434:Gastrointestinal
1242:
1238:Affected systems
1115:
1083:
1068:Chorioamnionitis
1061:
1032:Placenta praevia
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242:A&A Practice
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144:thrombocytopenia
105:thrombocytopenia
50:
49:
19:
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1952:Poland syndrome
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1613:
1597:Neonatal sepsis
1544:
1513:Musculoskeletal
1507:
1484:
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1383:Hydrops fetalis
1334:
1325:
1302:
1275:Pleural disease
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1195:Cephalohematoma
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944:article/1081910
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745:Further reading
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200:ultrasonography
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1308:Cardiovascular
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1080:umbilical cord
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860:Classification
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840:External links
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152:thrombocytosis
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1868:Lipodystrophy
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1161:Preterm birth
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1703:Panniculitis
1525:
1281:Pneumothorax
1273:
1187:
1180:Birth trauma
1122:Breech birth
1112:presentation
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515:(6). Wiley.
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343:February 17,
341:. Retrieved
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241:
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221:Panniculitis
189:
164:preeclampsia
161:
140:hypoglycemia
129:
117:erythematous
114:
101:constipation
89:hypoglycemia
61:panniculitis
56:
55:
1625:Miscarriage
1527:muscle tone
1393:Kernicterus
1246:Respiratory
1222:Erb's palsy
1127:Asynclitism
1095:Nuchal cord
196:skin biopsy
192:skin biopsy
176:hypothermia
85:dehydration
69:hypothermia
30:SCFN or SFN
27:Other names
1930:Congenital
1918:localized:
1741:Pancreatic
1635:Stillbirth
1592:Omphalitis
1553:Infections
1462:Integument
904:DiseasesDB
851:StatPearls
334:"UpToDate"
227:References
150:. Rarely,
41:Pediatrics
1746:Traumatic
1731:Factitial
1361:Anti-Kell
999:period /
997:perinatal
939:eMedicine
920:239094006
915:SNOMED CT
816:0340-6199
779:1875-9572
718:0736-8046
682:0009-9228
629:2090-6560
572:0736-8046
529:0736-8046
486:0736-8046
432:0007-0963
396:235481677
380:0736-8046
270:232160504
186:Diagnosis
36:Specialty
1971:Category
1893:partial:
1876:Acquired
1331:Bleeding
1022:placenta
953:Q7630991
832:23109123
824:21318229
787:28237247
734:29137741
726:25491115
647:32148979
588:26678688
580:12787278
537:44286466
494:30187956
448:29283658
440:17493069
388:34145911
338:UpToDate
262:33684082
210:See also
172:asphyxia
168:diabetes
121:alopecia
97:vomiting
93:seizures
1842:Chronic
1711:Lobular
1570:rubella
1200:Chignon
1054:chorion
949:Scholia
846:DermNet
638:7056997
73:hypoxia
65:hypoxia
1816:Septal
1145:Growth
1058:amnion
883:KC22.0
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158:Causes
146:, and
136:anemia
125:nodule
103:, and
43:
1837:Acute
1736:Gouty
1618:Other
1442:Ileus
1189:scalp
909:31377
898:P83.8
828:S2CID
730:S2CID
584:S2CID
533:S2CID
444:S2CID
392:S2CID
266:S2CID
1721:Cold
1376:Rh E
1371:Rh D
1366:Rh c
820:PMID
812:ISSN
783:PMID
775:ISSN
722:PMID
714:ISSN
678:ISSN
643:PMID
625:ISSN
611:2020
576:PMID
568:ISSN
525:ISSN
490:PMID
482:ISSN
436:PMID
428:ISSN
384:PMID
376:ISSN
345:2024
314:ISBN
289:ISBN
258:PMID
166:and
67:and
1464:and
1356:ABO
1351:HDN
1333:and
889:ICD
874:ICD
804:doi
800:170
765:doi
706:doi
670:doi
633:PMC
615:doi
560:doi
517:doi
474:doi
420:doi
416:156
368:doi
250:doi
1973::
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456:^
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198:,
190:A
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866:D
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252::
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