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According to the organization site, its goal is to "help build the industry that will cure the diseases of aging". It funds research and uses outreach and education in order to expedite the various regenerative medicine research programs that go together to make the SENS project. The foundation also
263:
supported the SENS program, many contended that the ultimate goals of de Grey's programme were too speculative given the state of technology and referred to it as "fantasy rather than science". By the mid-2010s, the rejuvenation approach gained traction with multiple startup companies created from
268:
pledged another €300 million for rejuvenation biotechnology startup companies. In 2021, Underdog
Pharmaceuticals, a startup company spun out from a research program at SENS Research Foundation, was awarded an Innovation Passport from the United Kingdom Medicines and Healthcare products Regulatory
269:
Agency, which intends to streamline the approval program of promising therapies. In August 2021, Aubrey de Grey was suspended from the foundation. The CEO of the SENS Research
Foundation, Jim O’Neill left in the preceding July, at the same time de Grey was suspended.
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and their common activities, during reading articles and public reports there are sometimes misunderstanding about their budgets, directions and amounts of donations which can be distributed between these organizations for various purposes.
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In 2011, Aubrey de Grey inherited $ 16.5 million on the death of his mother. Of this he assigned $ 13 million to fund SENS research, which by 2013 had the effect of roughly doubling the SRF yearly budget to $ 4 million.
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Underdog
Pharmaceuticals received an Innovation Passport, an accelerated regulatory pathway from the UK government for promising therapies, for a small molecule drug to treat
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The
Degradation of Tau Aggregates project seeks to remove aggregated tau proteins, which are part of age-related cognitive decline, Alzheimer's, and other tauopathies.
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in 2019 its income was $ 2,683,611 and expenses $ 4,361,258 ($ 2,331,364 on research, $ 859,222 on education, $ 642,056 on outreach, $ 582,616 on administration).
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in 2017 its income was $ 7,871,530 and expenses $ 3,915,682 ($ 2,146,412 on research, $ 920,533 on education, $ 172,380 on outreach, $ 676,534 on administration).
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The mitochondrial transplantation project aims to take advantage of the body's natural process of mitochondrial exchange for healthy mitochondrial transfusion.
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and Haseeb
Qureshi donated a total of $ 150,000 to SENS Research Foundation to combat aging and aging-related diseases at the choice of users of
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1270:"Fight Aging! Invests in Ichor Therapeutics to Support Development of a SENS Damage Repair Therapy for Macular Degeneration"
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236:. It was founded in 2009, located in Mountain View, California, US. The organization publishes its reports annually.
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has also taken part in and/or selectively funded extramural research at various other institutions, including
1490:[«King of Ethereum» Vitalik Buterin: the best thing to donate money for is the fight against aging].
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2020:
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donated $ 2 million to SENS in 2017–18, that's in addition to $ 1 million donated to
Methuselah Foundation.
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The SENS Research
Foundation (SRF) pursues research projects that correspond to the seven categories of
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Oisin
Biotechnologies (SENS seed-funded startup) has a precise targeting technology, which is based on
1354:
1302:"SENS Research Foundation & Underdog Pharmaceuticals jointly awarded $ 252,000 NIA research grant"
1488:""Король Эфириума" Виталик Бутерин: лучшее, на что стоит жертвовать деньги — это борьба со старением"
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Michael Greve
Announces a New €300 Million Fund for Investment in Rejuvenation Biotechnology Startups
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Before the foundation was founded in March 2009, the SENS research program was mainly pursued by the
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1432:"The Pineapple Fund Donates Millions to the Organ Preservation Alliance and Methuselah Foundation"
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Michael Greve, founder of
Forever Healthy, commits €300 million to advance rejuvenation startups
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OncoSENS's solution is to preemptively remove the genes for the telomere-lengthening machinery.
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cofounder Michael Antonov donated $ 1 million, of which $ 600,000 was a matching donation.
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1446:"SENS Research Foundation Receives $ 2.4 Million Ethereum Donation From Vitalik Buterin"
1206:"Stable nuclear expression of ATP8 and ATP6 genes rescues a mtDNA Complex V null mutant"
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899:"Science fact and the SENS agenda. What can we reasonably expect from ageing research?"
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1330:"Revel Pharmaceuticals Finally Seed Funded to Develop Glucosepane Cross-Link Breakers"
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In addition to research undertaken in-house at the Research Center in Mountain View,
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1256:"Engineering New Mitochondrial Genes to Restore Mitochondrial Function (MitoSENS)"
1167:"Selective Ablation of Senescent and Malignant Cells using Apoptotic Gene Therapy"
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1284:"Kizoo portfolio company Underdog awarded 'Innovation Passport' by UK Regulators"
1012:"Kizoo portfolio company Underdog awarded 'Innovation Passport' by UK Regulators"
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1461:"Vitalik Buterin: The Best Thing to Donate Money to is The Fight Against Aging"
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When the SENS rejuvenation approach was announced in the 2000s, while some
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donated $ 2.4 million in 2018. Then in 2020 Vitalik Buterin together with
1620:
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1222:
946:
Holliday R (April 2009). "The extreme arrogance of anti-aging medicine".
729:
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by clearing arterial plaques. Underdog and SRF received a grant from the
1372:"Internet Entrepreneur Jason Hope Pledges A Donation To SENS Foundation"
796:"Women In Longevity And The Renaissance Of The SENS Research Foundation"
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in 2018 – unclear, the annual report does not contain this information.
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Graphs are unavailable due to technical issues. There is more info on
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Graphs are unavailable due to technical issues. There is more info on
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genes was successful. Research was published in the peer-reviewed
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Revel Pharmaceuticals is developing therapeutics that can cleave
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1033:"Anti-aging foundation's CEO left amid probe of Aubrey de Grey"
651:
622:
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Warner H; Anderson J; Austad S; et al. (November 2005).
689:
Owing to the close relationship between SENS Foundation and
1103:"Functional Neuron Replacement to Rejuvenate the Neocortex"
1184:"MitoSENS: Preventing Damage from Mitochondrial Mutations"
697:
On December 9, 2010, Jason Hope, an entrepreneur based in
199:
1545:
1448:(Press release). SENS Research Foundation. 2018-02-02.
1120:"Plasmid based senolytics from Oisín Biotechnologies"
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therapy results in 75–90% reduction in tumor in mice.
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Michael Antonov Foundation: SENS Research Foundation
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Ichor Therapeutics is developing repair therapy for
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2012:
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346:seeking to replenish and regenerate the neocortex.
1343:SENS Research Foundation Research Advisory Board
681:
517:
2002:Lifespan: Why We Age – and Why We Don't Have To
1706:Strategies for engineered negligible senescence
1204:Boominathan, Amutha; et al. (2016-09-04).
1027:
1025:
292:Strategies for engineered negligible senescence
1568:
1355:"SENS Research Foundation 2022 Annual Report"
881:"SENS Research Foundation 2020 Annual Report"
875:
873:
861:"SENS Research Foundation 2019 Annual Report"
855:
853:
841:"SENS Research Foundation 2018 Annual Report"
835:
833:
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819:"SENS Research Foundation 2011 Annual Report"
813:
811:
8:
2116:Non-profit organizations based in California
368:from Oisin Biotechnologies, which is a SENS
30:
1141:"Systemic Senolysis in Naturally Aged Mice"
317:Description and related spin-off companies
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1561:
1553:
1316:"Catalyzing Degradation of Tau Aggregates"
36:
29:
1661:Index of topics related to life extension
1231:
1221:
922:
552:The SENS Research Foundation's research
307:
786:
1506:"Effective Altruism: Giving in Crypto"
1463:. LIFE EXTENSION ADVOCACY FOUNDATION.
1114:
1112:
7:
1393:"Interview with Aubrey de Grey, PhD"
794:Zhavoronkov, Alex (April 17, 2023).
766:Buck Institute for Research on Aging
1494:(in Russian). Komsomolskaya Pravda.
344:Albert Einstein College of Medicine
1286:. 8 September 2021. Archived from
1082:"RepleniSENS:Replacing Lost Cells"
1014:. 8 September 2021. Archived from
771:Life Extension Advocacy Foundation
25:
2121:Organizations established in 2009
342:SRF helps fund the Hebert lab at
278:conducts its own student program
1719:
1459:Elena, Milova (March 20, 2018).
1058:"About SENS Research Foundation"
701:, pledged a $ 500,000 donation.
656:
627:
466:to pursue this research further.
264:SENS research findings. In 2021
1736:Timeline of senescence research
1467:from the original on 2018-03-22
1420:Bitcoin Transaction f0aa1cc5bc…
1409:Bitcoin Transaction 10dd3b4bb1…
419:Initial proof of concept using
708:According SRF annual reports,
501:advanced glycation end-product
1:
1165:Dr. John Lewis (2018-10-11).
473:Extracellular waste products
464:National Institutes of Health
443:Intracellular waste products
2111:Life extension organizations
2106:Biogerontology organizations
744:as a result of open voting.
228:work for the application of
1863:Alliance for Aging Research
1519:2020 End of Year Fundraiser
1486:Анна ДОБРЮХА (2018-03-20).
1434:. Fight Aging!. 2018-01-29.
1332:. Fight Aging!. 2020-01-07.
1272:. Fight Aging!. 2016-08-15.
50:; 15 years ago
2137:
1898:Gerontology Research Group
1186:. SENS Research Foundation
1084:. SENS Research Foundation
289:
1938:MPI for Biology of Ageing
1717:
1671:Longevity escape velocity
1143:. YouTube. Archived from
960:10.1007/s10522-008-9170-6
168:Maria Entraigues-Abramson
35:
2101:Regenerative biomedicine
2049:Experimental Gerontology
1948:SENS Research Foundation
1172:. University of Alberta.
915:10.1038/sj.embor.7400555
353:Division-obsessed cells
214:SENS Research Foundation
31:SENS Research Foundation
2021:Ageing Research Reviews
1666:List of aging processes
1397:Life Extension Magazine
548:Research advisory board
218:non-profit organization
27:Non-profit organization
1711:Transhumanist politics
1210:Nucleic Acids Research
586:María Blasco Marhuenda
512:Research collaboration
430:Nucleic Acids Research
383:Death-resistant cells
2063:Rejuvenation Research
2056:Neurobiology of Aging
1933:Methuselah Foundation
776:Methuselah Foundation
691:Methuselah Foundation
542:University of Arizona
246:Methuselah Foundation
230:regenerative medicine
574:William A. Haseltine
530:Cambridge University
489:Extracellular matrix
453:macular degeneration
414:Allotopic expression
1908:Immortalist Society
1656:Indefinite lifespan
1636:Free-radical theory
1616:Calorie restriction
1606:Anti-aging movement
699:Scottsdale, Arizona
558:Pedro J. J. Alvarez
534:University of Texas
322:Cell loss and cell
32:
1978:The First Immortal
1374:. December 9, 2010
1304:. 9 December 2021.
1223:10.1093/nar/gkw756
1062:Official SENS site
610:Vladimir Skulachev
526:Harvard University
338:tissue engineering
2088:
2087:
1918:Insilico Medicine
1757:Eric R. Braverman
1701:Stem-cell therapy
1216:(19): 9342–9357.
738:Sam Bankman-Fried
678:
677:
649:
648:
509:
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395:' DNA expression.
314:Research program
297:Research programs
261:biogerontologists
222:research programs
210:
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159:Lisa Fabiny-Kiser
16:(Redirected from
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1986:Fantastic Voyage
1777:Leonard Hayflick
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1546:Official website
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578:Brian K. Kennedy
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248:, co-founded by
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1903:Human Longevity
1848:2045 Initiative
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1258:. 15 June 2021.
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606:Michael D. West
594:Nadia Rosenthal
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538:Rice University
522:Yale University
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460:atherosclerosis
393:senescent cells
303:cellular damage
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1290:on 2021-09-08.
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570:Judith Campisi
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83:Kevin Perrott
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1994:Ending Aging
1992:
1984:
1976:
1968:
1947:
1812:Durk Pearson
1797:Ray Kurzweil
1767:Laura Deming
1752:Bill Andrews
1691:Rejuvenation
1681:Nanomedicine
1641:Gene therapy
1525:
1514:
1500:
1491:
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1469:. Retrieved
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1376:. Retrieved
1366:
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1288:the original
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1178:
1160:
1149:. Retrieved
1145:the original
1135:
1124:. Retrieved
1097:
1086:. Retrieved
1076:
1065:. Retrieved
1061:
1052:
1041:. Retrieved
1039:. 2021-08-13
1036:
1016:the original
1006:
995:
984:
954:(2): 223–8.
951:
947:
941:
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903:EMBO Reports
902:
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799:
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761:Ending Aging
746:
728:
721:
707:
703:
696:
688:
551:
515:
428:
374:suicide gene
364:OncoSenX's (
328:RepleniSENS
300:
279:
276:
258:
243:
213:
211:
181:Michael Kope
173:Kevin Dewalt
165:(Chairman),
134:Area served
103:Rejuvenation
75:Michael Kope
1827:Roy Walford
1807:Liz Parrish
1646:Gerontology
732:co-founder
667:Phabricator
638:Phabricator
503:crosslinks.
491:stiffening
386:ApoptoSENS
370:seed-funded
254:David Gobel
2095:Categories
2073:Categories
2035:Aging Cell
1868:Altos Labs
1822:Sandy Shaw
1696:Senescence
1611:Biohacking
1584:Outline of
1378:2021-03-29
1190:2020-12-31
1151:2021-01-09
1126:2021-04-07
1088:2020-12-31
1067:2021-03-26
1043:2021-08-15
782:References
494:GlycoSENS
476:AmyloSENS
405:mutations
334:Stem cells
220:that does
154:Key people
120:California
79:Sarah Marr
1817:Mark Roth
1782:Saul Kent
1651:Glycation
1471:March 21,
1170:(lecture)
747:In 2020,
556:includes
446:LysoSENS
408:MitoSENS
372:startup)
356:OncoSENS
177:Jeff Hall
163:Bill Liao
93:501(c)(3)
71:Jeff Hall
2013:Journals
1631:Exercise
1621:Cryonics
1465:Archived
1242:27596602
968:18726707
933:16264422
755:See also
730:Ethereum
602:Jan Vijg
433:journal.
286:Research
109:Location
1883:BioViva
1492:Kp.ru -
1233:5100594
924:1371037
742:Twitter
669:and on
640:and on
366:spinout
324:atrophy
240:History
195:Website
63:Founder
55:2009-03
53: (
45:Founded
2005:(2019)
1997:(2007)
1989:(2004)
1981:(1998)
1973:(1982)
1888:Calico
1745:People
1729:Events
1626:Cyborg
1594:Issues
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976:764136
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801:Forbes
749:Oculus
608:, and
540:, and
161:(CEO)
143:Method
138:Global
2028:Aging
1962:Books
1893:ERIBA
1358:(PDF)
972:S2CID
884:(PDF)
864:(PDF)
844:(PDF)
822:(PDF)
273:Goals
234:aging
216:is a
202:.sens
99:Focus
1923:LEAF
1858:AgeX
1473:2018
1238:PMID
1037:STAT
964:PMID
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425:ATP6
423:and
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336:and
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204:.org
147:SENS
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