255:
232:
129:
154:
506:
261:
160:
1498:
1450:
Neesse A, Gangeswaran R, Luettges J, Feakins R, Weeks ME, Lemoine NR, Crnogorac-Jurcevic T (March 2007). "Sperm-associated antigen 1 is expressed early in pancreatic tumorigenesis and promotes motility of cancer cells".
1388:"Phosphoproteome analysis of capacitated human sperm. Evidence of tyrosine phosphorylation of a kinase-anchoring protein 3 and valosin-containing protein/p97 during capacitation"
268:
167:
1322:
Takaishi M, Huh N (October 1999). "A tetratricopeptide repeat-containing protein gene, tpis, whose expression is induced with differentiation of spermatogenic cells".
1266:
Zhang ML, Wang LF, Miao SY, Koide SS (December 1992). "Isolation and sequencing of the cDNA encoding the 75-kD human sperm protein related to infertility".
1421:
Kanazawa R, Komori S, Sakata K, Tanaka H, Sawai H, Tsuji Y, Koyama K (August 2003). "Isolation and characterization of a human sperm antigen gene h-Sp-1".
684:
665:
90:
1567:
1543:
1148:
1130:
1562:
254:
1168:"A sperm component, HSD-3.8 (SPAG1), interacts with G-protein beta 1 subunit and activates extracellular signal-regulated kinases (ERK)"
940:
1386:
Ficarro S, Chertihin O, Westbrook VA, White F, Jayes F, Kalab P, Marto JA, Shabanowitz J, Herr JC, Hunt DF, Visconti PE (March 2003).
947:
231:
1210:
1117:
1096:
1044:
The protein expressed by this gene is recognized by anti-sperm agglutinating antibodies from an infertile woman. Furthermore,
1113:
153:
128:
1092:
1068:
70:
267:
166:
260:
159:
1536:
1229:
Diekman AB, Herr JC (January 1997). "Sperm antigens and their use in the development of an immunocontraceptive".
729:
78:
1071:
involved in spermatogenesis and fertilization. Two transcript variants of this gene encode the same protein.
710:
1029:
implicates a role for these antibodies in blocking fertilization. Improved diagnosis and treatment of
1529:
1022:
142:
57:
1048:
of female rats with the recombinant human protein reduced fertility. This protein localizes to the
923:
913:
909:
905:
901:
882:
848:
838:
834:
830:
826:
807:
1476:
1254:
102:
897:
878:
874:
822:
803:
799:
1468:
1438:
1409:
1374:
1339:
1310:
1275:
1246:
1189:
50:
1513:
1460:
1430:
1399:
1364:
1331:
1300:
1238:
1179:
347:
278:
222:
177:
505:
98:
322:
1242:
599:
594:
578:
573:
557:
552:
547:
1556:
1434:
1049:
1034:
534:
1258:
82:
61:, CILD28, CT140, HSD-3.8, SP75, TPIS, HEL-S-268, sperm associated antigen 1, DNAAF13
1509:
1480:
1166:
Liu N, Qiao Y, Cai C, Lin W, Zhang J, Miao S, Zong S, Koide SS, Wang L (May 2006).
1053:
1045:
340:
119:
1351:
Lin W, Zhou X, Zhang M, Li Y, Miao S, Wang L, Zong S, Koide SS (September 2001).
106:
1353:"Expression and function of the HSD-3.8 gene encoding a testis-specific protein"
1153:
National Center for
Biotechnology Information, U.S. National Library of Medicine
1135:
National Center for
Biotechnology Information, U.S. National Library of Medicine
1060:
1052:
of germ cells in the testis and to the post-acrosomal plasma membrane of mature
1026:
423:
1030:
239:
136:
86:
1369:
1352:
1037:, are dependent on the identification and characterization of relevant sperm
1289:"Normalization and subtraction: two approaches to facilitate gene discovery"
629:
483:
361:
306:
293:
205:
192:
94:
1472:
1464:
1442:
1413:
1404:
1387:
1378:
1343:
1335:
1193:
1314:
1279:
1250:
987:
982:
971:
774:
755:
1305:
1288:
1038:
1003:
741:
696:
1064:
955:
651:
17:
1497:
1184:
1167:
614:
610:
1505:
1033:
infertility, as well as identification of proteins for targeted
1010:
74:
514:
330:
1517:
495:
1324:
896:
867:
821:
792:
1287:Bonaldo MF, Lennon G, Soares MB (September 1996).
1109:
1107:
1105:
1088:
1086:
1084:
277:
176:
1211:"Entrez Gene: SPAG1 sperm associated antigen 1"
27:Protein-coding gene in the species Homo sapiens
1114:GRCm38: Ensembl release 89: ENSMUSG00000037617
1067:activity. Thus, this protein may regulate GTP
1537:
8:
1231:American Journal of Reproductive Immunology
1093:GRCh38: Ensembl release 89: ENSG00000104450
1544:
1530:
893:
818:
625:
530:
318:
217:
114:
1403:
1368:
1304:
1183:
1205:
1203:
1080:
31:
282:
243:
238:
181:
140:
135:
7:
1494:
1492:
1392:The Journal of Biological Chemistry
1516:. You can help Knowledge (XXG) by
1423:International Journal of Andrology
1243:10.1111/j.1600-0897.1997.tb00199.x
864:
789:
765:
746:
720:
701:
675:
656:
500:
418:
356:
335:
25:
1006:that in humans is encoded by the
1496:
1435:10.1046/j.1365-2605.2003.00418.x
595:axonemal dynein complex assembly
504:
462:lumbar subsegment of spinal cord
266:
259:
253:
230:
165:
158:
152:
127:
515:More reference expression data
484:More reference expression data
384:olfactory zone of nasal mucosa
1:
1568:Human chromosome 8 gene stubs
251:
150:
1357:Molecular Human Reproduction
1069:signal transduction pathways
1563:Genes on human chromosome 8
1584:
1491:
1025:with cases of unexplained
1000:Sperm-associated antigen 1
1149:"Mouse PubMed Reference:"
1131:"Human PubMed Reference:"
986:
981:
977:
970:
954:
941:Chr 8: 100.16 – 100.26 Mb
935:
920:
871:
860:
845:
796:
785:
772:
768:
753:
749:
740:
727:
723:
708:
704:
695:
682:
678:
663:
659:
650:
635:
628:
624:
608:
533:
529:
512:
503:
494:
481:
430:
421:
392:mucosa of paranasal sinus
372:bronchial epithelial cell
368:
359:
329:
321:
317:
300:
287:
250:
229:
220:
216:
199:
186:
149:
126:
117:
113:
68:
65:
55:
48:
43:
39:
34:
948:Chr 15: 36.18 – 36.24 Mb
1268:Chinese Medical Journal
1172:Frontiers in Bioscience
1063:binds GTP and exhibits
376:mucosa of sigmoid colon
1465:10.1038/sj.onc.1209961
1405:10.1074/jbc.M202325200
1370:10.1093/molehr/7.9.811
1336:10.1006/bbrc.1999.1477
1023:anti-sperm antibodies
380:palpebral conjunctiva
245:Chromosome 15 (mouse)
600:single fertilization
458:facial motor nucleus
143:Chromosome 8 (human)
1021:The correlation of
470:seminiferous tubule
400:epithelium of colon
1504:This article on a
1306:10.1101/gr.6.9.791
730:ENSMUSG00000037617
588:Biological process
567:Cellular component
558:hydrolase activity
548:nucleotide binding
541:Molecular function
396:right uterine tube
1525:
1524:
997:
996:
993:
992:
966:
965:
931:
930:
890:
889:
856:
855:
815:
814:
781:
780:
762:
761:
736:
735:
717:
716:
691:
690:
672:
671:
620:
619:
525:
524:
521:
520:
490:
489:
477:
476:
466:cerebellar cortex
415:
414:
313:
312:
212:
211:
107:SPAG1 - orthologs
16:(Redirected from
1575:
1546:
1539:
1532:
1500:
1493:
1484:
1446:
1417:
1407:
1398:(13): 11579–89.
1382:
1372:
1347:
1318:
1308:
1283:
1274:(12): 998–1003.
1262:
1215:
1214:
1207:
1198:
1197:
1187:
1163:
1157:
1156:
1145:
1139:
1138:
1127:
1121:
1111:
1100:
1090:
979:
978:
950:
943:
926:
894:
885:
865:
861:RefSeq (protein)
851:
819:
810:
790:
766:
747:
721:
702:
676:
657:
626:
531:
517:
508:
501:
486:
438:secondary oocyte
426:
424:Top expressed in
419:
364:
362:Top expressed in
357:
336:
319:
309:
296:
285:
270:
263:
257:
246:
234:
218:
208:
195:
184:
169:
162:
156:
145:
131:
115:
109:
60:
53:
32:
21:
1583:
1582:
1578:
1577:
1576:
1574:
1573:
1572:
1553:
1552:
1551:
1550:
1489:
1487:
1459:(11): 1533–45.
1449:
1420:
1385:
1350:
1321:
1293:Genome Research
1286:
1265:
1228:
1224:
1222:Further reading
1219:
1218:
1209:
1208:
1201:
1165:
1164:
1160:
1147:
1146:
1142:
1129:
1128:
1124:
1112:
1103:
1091:
1082:
1077:
1050:plasma membrane
1019:
988:View/Edit Mouse
983:View/Edit Human
946:
939:
936:Location (UCSC)
922:
916:
912:
908:
904:
900:
881:
877:
873:
847:
841:
837:
833:
829:
825:
806:
802:
798:
711:ENSG00000104450
604:
583:
562:
513:
482:
473:
468:
464:
460:
456:
452:
448:
444:
440:
436:
422:
411:
406:
402:
398:
394:
390:
386:
382:
378:
374:
360:
304:
291:
284:15|15 B3.1
283:
273:
272:
271:
264:
244:
221:Gene location (
203:
190:
182:
172:
171:
170:
163:
141:
118:Gene location (
69:
56:
49:
28:
23:
22:
15:
12:
11:
5:
1581:
1579:
1571:
1570:
1565:
1555:
1554:
1549:
1548:
1541:
1534:
1526:
1523:
1522:
1501:
1486:
1485:
1447:
1418:
1383:
1348:
1319:
1299:(9): 791–806.
1284:
1263:
1225:
1223:
1220:
1217:
1216:
1199:
1158:
1140:
1122:
1101:
1079:
1078:
1076:
1073:
1018:
1015:
995:
994:
991:
990:
985:
975:
974:
968:
967:
964:
963:
961:
959:
952:
951:
944:
937:
933:
932:
929:
928:
918:
917:
891:
888:
887:
869:
868:
862:
858:
857:
854:
853:
843:
842:
816:
813:
812:
794:
793:
787:
783:
782:
779:
778:
770:
769:
763:
760:
759:
751:
750:
744:
738:
737:
734:
733:
725:
724:
718:
715:
714:
706:
705:
699:
693:
692:
689:
688:
680:
679:
673:
670:
669:
661:
660:
654:
648:
647:
642:
637:
633:
632:
622:
621:
618:
617:
606:
605:
603:
602:
597:
591:
589:
585:
584:
582:
581:
576:
570:
568:
564:
563:
561:
560:
555:
550:
544:
542:
538:
537:
527:
526:
523:
522:
519:
518:
510:
509:
498:
492:
491:
488:
487:
479:
478:
475:
474:
472:
471:
467:
463:
459:
455:
451:
450:primary oocyte
447:
443:
439:
435:
431:
428:
427:
416:
413:
412:
410:
409:
405:
401:
397:
393:
389:
385:
381:
377:
373:
369:
366:
365:
353:
352:
344:
333:
327:
326:
323:RNA expression
315:
314:
311:
310:
302:
298:
297:
289:
286:
281:
275:
274:
265:
258:
252:
248:
247:
242:
236:
235:
227:
226:
214:
213:
210:
209:
201:
197:
196:
188:
185:
180:
174:
173:
164:
157:
151:
147:
146:
139:
133:
132:
124:
123:
111:
110:
67:
63:
62:
54:
46:
45:
41:
40:
37:
36:
26:
24:
14:
13:
10:
9:
6:
4:
3:
2:
1580:
1569:
1566:
1564:
1561:
1560:
1558:
1547:
1542:
1540:
1535:
1533:
1528:
1527:
1521:
1519:
1515:
1511:
1507:
1502:
1499:
1495:
1490:
1482:
1478:
1474:
1470:
1466:
1462:
1458:
1454:
1448:
1444:
1440:
1436:
1432:
1429:(4): 226–35.
1428:
1424:
1419:
1415:
1411:
1406:
1401:
1397:
1393:
1389:
1384:
1380:
1376:
1371:
1366:
1362:
1358:
1354:
1349:
1345:
1341:
1337:
1333:
1329:
1325:
1320:
1316:
1312:
1307:
1302:
1298:
1294:
1290:
1285:
1281:
1277:
1273:
1269:
1264:
1260:
1256:
1252:
1248:
1244:
1240:
1236:
1232:
1227:
1226:
1221:
1212:
1206:
1204:
1200:
1195:
1191:
1186:
1181:
1177:
1173:
1169:
1162:
1159:
1154:
1150:
1144:
1141:
1136:
1132:
1126:
1123:
1119:
1115:
1110:
1108:
1106:
1102:
1098:
1094:
1089:
1087:
1085:
1081:
1074:
1072:
1070:
1066:
1062:
1057:
1055:
1051:
1047:
1042:
1040:
1036:
1035:contraception
1032:
1028:
1024:
1016:
1014:
1012:
1009:
1005:
1001:
989:
984:
980:
976:
973:
969:
962:
960:
957:
953:
949:
945:
942:
938:
934:
927:
925:
919:
915:
911:
907:
903:
899:
895:
892:
886:
884:
880:
876:
870:
866:
863:
859:
852:
850:
844:
840:
836:
832:
828:
824:
820:
817:
811:
809:
805:
801:
795:
791:
788:
786:RefSeq (mRNA)
784:
777:
776:
771:
767:
764:
758:
757:
752:
748:
745:
743:
739:
732:
731:
726:
722:
719:
713:
712:
707:
703:
700:
698:
694:
687:
686:
681:
677:
674:
668:
667:
662:
658:
655:
653:
649:
646:
643:
641:
638:
634:
631:
627:
623:
616:
612:
607:
601:
598:
596:
593:
592:
590:
587:
586:
580:
577:
575:
572:
571:
569:
566:
565:
559:
556:
554:
551:
549:
546:
545:
543:
540:
539:
536:
535:Gene ontology
532:
528:
516:
511:
507:
502:
499:
497:
493:
485:
480:
469:
465:
461:
457:
453:
449:
445:
441:
437:
433:
432:
429:
425:
420:
417:
407:
404:skin of thigh
403:
399:
395:
391:
387:
383:
379:
375:
371:
370:
367:
363:
358:
355:
354:
351:
349:
345:
343:
342:
338:
337:
334:
332:
328:
324:
320:
316:
308:
303:
299:
295:
290:
280:
276:
269:
262:
256:
249:
241:
237:
233:
228:
224:
219:
215:
207:
202:
198:
194:
189:
179:
175:
168:
161:
155:
148:
144:
138:
134:
130:
125:
121:
116:
112:
108:
104:
100:
96:
92:
88:
84:
80:
76:
72:
64:
59:
52:
47:
42:
38:
33:
30:
19:
1518:expanding it
1510:chromosome 8
1503:
1488:
1456:
1452:
1426:
1422:
1395:
1391:
1363:(9): 811–8.
1360:
1356:
1327:
1323:
1296:
1292:
1271:
1267:
1237:(1): 111–7.
1234:
1230:
1185:10.2741/1913
1175:
1171:
1161:
1152:
1143:
1134:
1125:
1059:Recombinant
1058:
1046:immunization
1043:
1020:
1007:
999:
998:
924:NP_001346913
921:
914:NP_001346912
910:NP_001346911
906:NP_001346910
902:NP_001346909
883:NP_001361250
872:
849:NM_001359984
846:
839:NM_001359983
835:NM_001359982
831:NM_001359981
827:NM_001359980
808:NM_001374321
797:
773:
754:
728:
709:
683:
664:
644:
639:
454:motor neuron
442:spermatocyte
346:
339:
204:100,259,278
191:100,157,906
66:External IDs
29:
1330:(1): 81–5.
1178:: 1679–89.
1061:polypeptide
1054:spermatozoa
1031:immunologic
1027:infertility
553:GTP binding
408:oral cavity
305:36,235,767
292:36,178,245
44:Identifiers
1557:Categories
1120:, May 2017
1099:, May 2017
1075:References
350:(ortholog)
87:HomoloGene
1508:on human
898:NP_036161
879:NP_757367
875:NP_003105
823:NM_012031
804:NM_172218
800:NM_003114
630:Orthologs
574:cytoplasm
446:spermatid
95:GeneCards
1473:16983343
1453:Oncogene
1443:12846798
1414:12509440
1379:11517287
1344:10527845
1259:39710127
1194:16368546
1116:–
1095:–
1039:antigens
1017:Function
972:Wikidata
609:Sources:
1481:1103473
1315:8889548
1280:1299558
1251:9138444
1118:Ensembl
1097:Ensembl
1004:protein
742:UniProt
697:Ensembl
636:Species
615:QuickGO
579:cytosol
325:pattern
83:1349387
51:Aliases
1479:
1471:
1441:
1412:
1377:
1342:
1313:
1278:
1257:
1249:
1192:
1065:GTPase
958:search
956:PubMed
775:Q80ZX8
756:Q07617
652:Entrez
496:BioGPS
434:zygote
388:rectum
183:8q22.2
75:603395
1512:is a
1477:S2CID
1255:S2CID
1008:SPAG1
1002:is a
685:26942
645:Mouse
640:Human
611:Amigo
348:Mouse
341:Human
288:Start
223:Mouse
187:Start
120:Human
99:SPAG1
58:SPAG1
35:SPAG1
18:SPAG1
1514:stub
1506:gene
1469:PMID
1439:PMID
1410:PMID
1375:PMID
1340:PMID
1311:PMID
1276:PMID
1247:PMID
1190:PMID
1011:gene
666:6674
331:Bgee
279:Band
240:Chr.
178:Band
137:Chr.
91:8081
71:OMIM
1461:doi
1431:doi
1400:doi
1396:278
1365:doi
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