242:
219:
116:
141:
493:
500:
248:
147:
1776:
1663:
Rual JF, Venkatesan K, Hao T, Hirozane-Kishikawa T, Dricot A, Li N, Berriz GF, Gibbons FD, Dreze M, Ayivi-Guedehoussou N, Klitgord N, Simon C, Boxem M, Milstein S, Rosenberg J, Goldberg DS, Zhang LV, Wong SL, Franklin G, Li S, Albala JS, Lim J, Fraughton C, Llamosas E, Cevik S, Bex C, Lamesch P,
1615:
Stelzl U, Worm U, Lalowski M, Haenig C, Brembeck FH, Goehler H, Stroedicke M, Zenkner M, Schoenherr A, Koeppen S, Timm J, Mintzlaff S, Abraham C, Bock N, Kietzmann S, Goedde A, Toksöz E, Droege A, Krobitsch S, Korn B, Birchmeier W, Lehrach H, Wanker EE (September 2005). "A human protein-protein
1427:
Neidhart S, Antonsson B, Gilliéron C, Vilbois F, Grenningloh G, Arkinstall S (November 2001). "c-Jun N-terminal kinase-3 (JNK3)/stress-activated protein kinase-beta (SAPKbeta) binds and phosphorylates the neuronal microtubule regulator SCG10".
1709:
Lee HS, Lee DC, Park MH, Yang SJ, Lee JJ, Kim DM, Jang Y, Lee JH, Choi JY, Kang YK, Kim DI, Park KC, Kim SY, Yoo HS, Choi EJ, Yeom YI (July 2006). "STMN2 is a novel target of beta-catenin/TCF-mediated transcription in human hepatoma cells".
1739:
Manna T, Grenningloh G, Miller HP, Wilson L (March 2007). "Stathmin family protein SCG10 differentially regulates the plus and minus end dynamics of microtubules at steady state in vitro: implications for its role in neurite outgrowth".
1324:
Antonsson B, Lütjens R, Di Paolo G, Kassel D, Allet B, Bernard A, Catsicas S, Grenningloh G (April 1997). "Purification, characterization, and in vitro phosphorylation of the neuron-specific membrane-associated protein SCG10".
1664:
Sikorski RS, Vandenhaute J, Zoghbi HY, Smolyar A, Bosak S, Sequerra R, Doucette-Stamm L, Cusick ME, Hill DE, Roth FP, Vidal M (October 2005). "Towards a proteome-scale map of the human protein-protein interaction network".
1389:
Lutjens R, Igarashi M, Pellier V, Blasey H, Di Paolo G, Ruchti E, Pfulg C, Staple JK, Catsicas S, Grenningloh G (July 2000). "Localization and targeting of SCG10 to the trans-Golgi apparatus and growth cone vesicles".
255:
154:
1180:
Okazaki T, Wang H, Masliah E, Cao M, Johnson SA, Sundsmo M, Saitoh T, Mori N (June 1996). "SCG10, a neuron-specific growth-associated protein in
Alzheimer's disease".
1356:"Identification of in vitro phosphorylation sites in the growth cone protein SCG10. Effect Of phosphorylation site mutants on microtubule-destabilizing activity"
768:
749:
77:
1500:
Greka A, Navarro B, Oancea E, Duggan A, Clapham DE (August 2003). "TRPC5 is a regulator of hippocampal neurite length and growth cone morphology".
1845:
1821:
1162:
1144:
1840:
241:
976:
218:
1270:
983:
1131:
1110:
1127:
140:
115:
1106:
1228:"RGS6 interacts with SCG10 and promotes neuronal differentiation. Role of the G gamma subunit-like (GGL) domain of RGS6"
57:
1078:
254:
153:
247:
146:
1814:
813:
65:
794:
1467:"The interaction of RGSZ1 with SCG10 attenuates the ability of SCG10 to promote microtubule disassembly"
1289:
Di Paolo G, Lutjens R, Pellier V, Stimpson SA, Beuchat MH, Catsicas S, Grenningloh G (February 1997).
1807:
1673:
129:
44:
934:
883:
1697:
1651:
1568:
1525:
1453:
1415:
1205:
89:
959:
938:
908:
887:
1757:
1727:
1689:
1643:
1603:
1582:"Systematic identification and analysis of mammalian small ubiquitin-like modifier substrates"
1560:
1517:
1488:
1445:
1407:
1377:
1342:
1312:
1249:
1197:
492:
37:
1791:
1749:
1719:
1681:
1633:
1625:
1593:
1550:
1509:
1478:
1437:
1399:
1367:
1334:
1302:
1291:"Targeting of SCG10 to the area of the Golgi complex is mediated by its NH2-terminal region"
1239:
1189:
334:
265:
209:
164:
499:
85:
1638:
309:
1677:
1354:
Antonsson B, Kassel DB, Di Paolo G, Lutjens R, Riederer BM, Grenningloh G (April 1998).
1555:
1538:
1441:
683:
678:
673:
668:
663:
658:
653:
648:
643:
638:
622:
617:
612:
607:
602:
597:
592:
587:
582:
577:
572:
567:
551:
546:
541:
1834:
1403:
1193:
528:
1572:
1457:
1419:
1209:
1787:
1701:
1655:
1529:
327:
106:
69:
93:
1167:
National Center for
Biotechnology Information, U.S. National Library of Medicine
1149:
National Center for
Biotechnology Information, U.S. National Library of Medicine
1723:
1629:
410:
1066:
226:
123:
73:
1372:
1355:
713:
470:
348:
293:
280:
192:
179:
81:
1761:
1731:
1693:
1647:
1607:
1598:
1581:
1564:
1521:
1492:
1483:
1466:
1449:
1411:
1338:
1307:
1290:
1253:
1244:
1227:
1381:
1346:
1316:
1201:
1023:
1018:
1062:
1058:
1007:
858:
839:
1685:
1539:"A small modulatory dsRNA specifies the fate of adult neural stem cells"
1039:
825:
780:
1753:
991:
735:
1775:
1513:
1069:
sequence similarity with the phosphoprotein stathmin (MIM 151442).
1537:
Kuwabara T, Hsieh J, Nakashima K, Taira K, Gage FH (March 2004).
698:
694:
1783:
1082:
1046:
508:
61:
1616:
interaction network: a resource for annotating the proteome".
659:
regulation of microtubule polymerization or depolymerization
317:
1795:
482:
664:
positive regulation of neuron projection development
644:
negative regulation of neuron projection development
1712:
1065:growth-associated protein which shares significant
952:
927:
901:
876:
669:
positive regulation of microtubule depolymerization
654:
negative regulation of microtubule depolymerization
457:
dentate gyrus of hippocampal formation granule cell
1123:
1121:
1119:
1102:
1100:
1098:
649:negative regulation of microtubule polymerization
639:cellular response to nerve growth factor stimulus
264:
163:
1226:Liu Z, Chatterjee TK, Fisher RA (October 2002).
16:Protein-coding gene in the species Homo sapiens
1465:Nixon AB, Grenningloh G, Casey PJ (May 2002).
1221:
1219:
1128:GRCm38: Ensembl release 89: ENSMUSG00000027500
1815:
8:
1107:GRCh38: Ensembl release 89: ENSG00000104435
1822:
1808:
709:
524:
305:
204:
101:
1637:
1597:
1554:
1482:
1371:
1306:
1243:
1580:Gocke CB, Yu H, Kang J (February 2005).
1265:
1263:
1094:
684:regulation of cytoskeleton organization
18:
269:
230:
225:
168:
127:
122:
7:
1772:
1770:
1392:The European Journal of Neuroscience
1271:"Entrez Gene: STMN2 stathmin-like 2"
1586:The Journal of Biological Chemistry
1471:The Journal of Biological Chemistry
1360:The Journal of Biological Chemistry
1327:Protein Expression and Purification
1295:The Journal of Biological Chemistry
1232:The Journal of Biological Chemistry
1794:. You can help Knowledge (XXG) by
949:
924:
898:
873:
849:
830:
804:
785:
759:
740:
487:
405:
343:
322:
14:
1042:that in humans is encoded by the
542:calcium-dependent protein binding
371:lateral nuclear group of thalamus
1774:
1404:10.1046/j.1460-9568.2000.00112.x
498:
491:
253:
246:
240:
217:
152:
145:
139:
114:
613:perinuclear region of cytoplasm
1639:11858/00-001M-0000-0010-8592-0
509:More reference expression data
471:More reference expression data
1:
1846:Human chromosome 8 gene stubs
1556:10.1016/S0092-8674(04)00248-X
1442:10.1016/S0014-5793(01)03090-3
679:neuron projection development
238:
137:
1194:10.1016/0197-4580(95)02001-2
674:microtubule depolymerization
429:anterior horn of spinal cord
1841:Genes on human chromosome 8
395:paraflocculus of cerebellum
383:superior vestibular nucleus
48:, SCG10, SCGN10, stathmin 2
1862:
1769:
1724:10.1016/j.bbrc.2006.05.017
1630:10.1016/j.cell.2005.08.029
421:superior cervical ganglion
1163:"Mouse PubMed Reference:"
1145:"Human PubMed Reference:"
1022:
1017:
1013:
1006:
990:
971:
956:
931:
920:
905:
880:
869:
856:
852:
837:
833:
824:
811:
807:
792:
788:
779:
766:
762:
747:
743:
734:
719:
712:
708:
692:
527:
523:
506:
490:
481:
468:
417:
408:
355:
346:
316:
308:
304:
287:
274:
237:
216:
207:
203:
186:
173:
136:
113:
104:
100:
55:
52:
42:
35:
30:
26:
21:
1077:STMN2 has been shown to
1373:10.1074/jbc.273.14.8439
977:Chr 8: 79.61 – 79.67 Mb
1599:10.1074/jbc.M411718200
1484:10.1074/jbc.M201065200
1339:10.1006/prep.1996.0710
1308:10.1074/jbc.272.8.5175
1245:10.1074/jbc.M205908200
1182:Neurobiology of Aging
984:Chr 3: 8.57 – 8.63 Mb
437:medial dorsal nucleus
391:cerebellar hemisphere
441:facial motor nucleus
232:Chromosome 3 (mouse)
130:Chromosome 8 (human)
1686:10.1038/nature04209
1678:2005Natur.437.1173R
1502:Nature Neuroscience
375:ganglionic eminence
271:3 A1|3 2.15 cM
1782:This article on a
1057:Superior cervical
814:ENSMUSG00000027500
632:Biological process
608:neuronal cell body
561:Cellular component
535:Molecular function
433:lobe of cerebellum
1803:
1802:
1754:10.1021/bi061819d
1033:
1032:
1029:
1028:
1002:
1001:
967:
966:
946:
945:
916:
915:
895:
894:
865:
864:
846:
845:
820:
819:
801:
800:
775:
774:
756:
755:
704:
703:
618:neuron projection
519:
518:
515:
514:
477:
476:
464:
463:
453:medulla oblongata
445:cerebellar vermis
402:
401:
363:cerebellar vermis
300:
299:
199:
198:
94:STMN2 - orthologs
1853:
1824:
1817:
1810:
1778:
1771:
1765:
1735:
1705:
1672:(7062): 1173–8.
1659:
1641:
1611:
1601:
1576:
1558:
1533:
1496:
1486:
1477:(20): 18127–33.
1461:
1423:
1385:
1375:
1350:
1320:
1310:
1275:
1274:
1267:
1258:
1257:
1247:
1223:
1214:
1213:
1177:
1171:
1170:
1159:
1153:
1152:
1141:
1135:
1125:
1114:
1104:
1015:
1014:
986:
979:
962:
950:
941:
925:
921:RefSeq (protein)
911:
899:
890:
874:
850:
831:
805:
786:
760:
741:
710:
525:
511:
502:
495:
488:
473:
413:
411:Top expressed in
406:
351:
349:Top expressed in
344:
323:
306:
296:
283:
272:
257:
250:
244:
233:
221:
205:
195:
182:
171:
156:
149:
143:
132:
118:
102:
96:
47:
40:
19:
1861:
1860:
1856:
1855:
1854:
1852:
1851:
1850:
1831:
1830:
1829:
1828:
1768:
1748:(11): 3543–52.
1738:
1708:
1662:
1614:
1579:
1536:
1499:
1464:
1426:
1388:
1366:(14): 8439–46.
1353:
1323:
1288:
1284:
1282:Further reading
1279:
1278:
1269:
1268:
1261:
1238:(40): 37832–9.
1225:
1224:
1217:
1179:
1178:
1174:
1161:
1160:
1156:
1143:
1142:
1138:
1126:
1117:
1105:
1096:
1091:
1075:
1055:
1024:View/Edit Mouse
1019:View/Edit Human
982:
975:
972:Location (UCSC)
958:
937:
933:
907:
886:
882:
795:ENSG00000104435
688:
627:
588:cell projection
583:Golgi apparatus
556:
552:protein binding
547:tubulin binding
507:
497:
496:
469:
460:
455:
451:
449:cingulate gyrus
447:
443:
439:
435:
431:
427:
423:
409:
398:
393:
389:
385:
381:
377:
373:
369:
365:
361:
347:
291:
278:
270:
260:
259:
258:
251:
231:
208:Gene location (
190:
177:
169:
159:
158:
157:
150:
128:
105:Gene location (
56:
43:
36:
17:
12:
11:
5:
1859:
1857:
1849:
1848:
1843:
1833:
1832:
1827:
1826:
1819:
1812:
1804:
1801:
1800:
1779:
1767:
1766:
1736:
1718:(3): 1059–67.
1706:
1660:
1612:
1592:(6): 5004–12.
1577:
1534:
1514:10.1038/nn1092
1497:
1462:
1424:
1398:(7): 2224–34.
1386:
1351:
1321:
1301:(8): 5175–82.
1285:
1283:
1280:
1277:
1276:
1259:
1215:
1172:
1154:
1136:
1115:
1093:
1092:
1090:
1087:
1074:
1071:
1054:
1051:
1031:
1030:
1027:
1026:
1021:
1011:
1010:
1004:
1003:
1000:
999:
997:
995:
988:
987:
980:
973:
969:
968:
965:
964:
954:
953:
947:
944:
943:
929:
928:
922:
918:
917:
914:
913:
903:
902:
896:
893:
892:
878:
877:
871:
867:
866:
863:
862:
854:
853:
847:
844:
843:
835:
834:
828:
822:
821:
818:
817:
809:
808:
802:
799:
798:
790:
789:
783:
777:
776:
773:
772:
764:
763:
757:
754:
753:
745:
744:
738:
732:
731:
726:
721:
717:
716:
706:
705:
702:
701:
690:
689:
687:
686:
681:
676:
671:
666:
661:
656:
651:
646:
641:
635:
633:
629:
628:
626:
625:
620:
615:
610:
605:
600:
595:
590:
585:
580:
575:
570:
564:
562:
558:
557:
555:
554:
549:
544:
538:
536:
532:
531:
521:
520:
517:
516:
513:
512:
504:
503:
485:
479:
478:
475:
474:
466:
465:
462:
461:
459:
458:
454:
450:
446:
442:
438:
434:
430:
426:
422:
418:
415:
414:
403:
400:
399:
397:
396:
392:
388:
384:
380:
376:
372:
368:
367:spinal ganglia
364:
360:
356:
353:
352:
340:
339:
331:
320:
314:
313:
310:RNA expression
302:
301:
298:
297:
289:
285:
284:
276:
273:
268:
262:
261:
252:
245:
239:
235:
234:
229:
223:
222:
214:
213:
201:
200:
197:
196:
188:
184:
183:
175:
172:
167:
161:
160:
151:
144:
138:
134:
133:
126:
120:
119:
111:
110:
98:
97:
54:
50:
49:
41:
33:
32:
28:
27:
24:
23:
15:
13:
10:
9:
6:
4:
3:
2:
1858:
1847:
1844:
1842:
1839:
1838:
1836:
1825:
1820:
1818:
1813:
1811:
1806:
1805:
1799:
1797:
1793:
1789:
1785:
1780:
1777:
1773:
1763:
1759:
1755:
1751:
1747:
1743:
1737:
1733:
1729:
1725:
1721:
1717:
1713:
1707:
1703:
1699:
1695:
1691:
1687:
1683:
1679:
1675:
1671:
1667:
1661:
1657:
1653:
1649:
1645:
1640:
1635:
1631:
1627:
1624:(6): 957–68.
1623:
1619:
1613:
1609:
1605:
1600:
1595:
1591:
1587:
1583:
1578:
1574:
1570:
1566:
1562:
1557:
1552:
1549:(6): 779–93.
1548:
1544:
1540:
1535:
1531:
1527:
1523:
1519:
1515:
1511:
1508:(8): 837–45.
1507:
1503:
1498:
1494:
1490:
1485:
1480:
1476:
1472:
1468:
1463:
1459:
1455:
1451:
1447:
1443:
1439:
1436:(2): 259–64.
1435:
1431:
1425:
1421:
1417:
1413:
1409:
1405:
1401:
1397:
1393:
1387:
1383:
1379:
1374:
1369:
1365:
1361:
1357:
1352:
1348:
1344:
1340:
1336:
1333:(3): 363–71.
1332:
1328:
1322:
1318:
1314:
1309:
1304:
1300:
1296:
1292:
1287:
1286:
1281:
1272:
1266:
1264:
1260:
1255:
1251:
1246:
1241:
1237:
1233:
1229:
1222:
1220:
1216:
1211:
1207:
1203:
1199:
1195:
1191:
1188:(6): 883–94.
1187:
1183:
1176:
1173:
1168:
1164:
1158:
1155:
1150:
1146:
1140:
1137:
1133:
1129:
1124:
1122:
1120:
1116:
1112:
1108:
1103:
1101:
1099:
1095:
1088:
1086:
1084:
1080:
1072:
1070:
1068:
1064:
1060:
1052:
1050:
1048:
1045:
1041:
1037:
1025:
1020:
1016:
1012:
1009:
1005:
998:
996:
993:
989:
985:
981:
978:
974:
970:
963:
961:
955:
951:
948:
942:
940:
936:
930:
926:
923:
919:
912:
910:
904:
900:
897:
891:
889:
885:
879:
875:
872:
870:RefSeq (mRNA)
868:
861:
860:
855:
851:
848:
842:
841:
836:
832:
829:
827:
823:
816:
815:
810:
806:
803:
797:
796:
791:
787:
784:
782:
778:
771:
770:
765:
761:
758:
752:
751:
746:
742:
739:
737:
733:
730:
727:
725:
722:
718:
715:
711:
707:
700:
696:
691:
685:
682:
680:
677:
675:
672:
670:
667:
665:
662:
660:
657:
655:
652:
650:
647:
645:
642:
640:
637:
636:
634:
631:
630:
624:
623:lamellipodium
621:
619:
616:
614:
611:
609:
606:
604:
601:
599:
596:
594:
591:
589:
586:
584:
581:
579:
576:
574:
571:
569:
566:
565:
563:
560:
559:
553:
550:
548:
545:
543:
540:
539:
537:
534:
533:
530:
529:Gene ontology
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522:
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467:
456:
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425:barrel cortex
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379:Pars compacta
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1796:expanding it
1788:chromosome 8
1781:
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1742:Biochemistry
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1621:
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1430:FEBS Letters
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1076:
1073:Interactions
1056:
1043:
1035:
1034:
957:
935:NP_001186143
932:
906:
884:NM_001199214
881:
857:
838:
812:
793:
767:
748:
728:
723:
387:frontal pole
333:
326:
53:External IDs
598:growth cone
191:79,666,158
178:79,611,117
31:Identifiers
1835:Categories
1134:, May 2017
1113:, May 2017
1089:References
1067:amino acid
1036:Stathmin-2
337:(ortholog)
292:8,626,666
279:8,574,420
74:HomoloGene
1786:on human
1061:-10 is a
960:NP_079561
939:NP_008960
909:NM_025285
888:NM_007029
714:Orthologs
568:cytoplasm
82:GeneCards
1762:17311410
1732:16712787
1694:16189514
1648:16169070
1608:15561718
1573:12656737
1565:15035981
1522:12858178
1493:11882662
1458:84253949
1450:11718727
1420:41593815
1412:10947801
1254:12140291
1210:54320124
1130:–
1109:–
1079:interact
1063:neuronal
1059:ganglion
1053:Function
1008:Wikidata
693:Sources:
593:membrane
578:endosome
1702:4427026
1674:Bibcode
1656:8235923
1530:7523946
1382:9525956
1347:9126608
1317:9030585
1202:8622778
1132:Ensembl
1111:Ensembl
1040:protein
826:UniProt
781:Ensembl
720:Species
699:QuickGO
573:vesicle
312:pattern
170:8q21.13
38:Aliases
1760:
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1666:Nature
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994:search
992:PubMed
859:P55821
840:Q93045
736:Entrez
483:BioGPS
62:600621
1790:is a
1698:S2CID
1652:S2CID
1569:S2CID
1526:S2CID
1454:S2CID
1416:S2CID
1206:S2CID
1081:with
1044:STMN2
1038:is a
769:20257
750:11075
729:Mouse
724:Human
695:Amigo
335:Mouse
328:Human
275:Start
210:Mouse
174:Start
107:Human
86:STMN2
70:98241
45:STMN2
22:STMN2
1792:stub
1784:gene
1758:PMID
1728:PMID
1690:PMID
1644:PMID
1618:Cell
1604:PMID
1561:PMID
1543:Cell
1518:PMID
1489:PMID
1446:PMID
1408:PMID
1378:PMID
1343:PMID
1313:PMID
1250:PMID
1198:PMID
1083:RGS6
1047:gene
603:axon
359:pons
318:Bgee
266:Band
227:Chr.
165:Band
124:Chr.
78:5102
58:OMIM
1750:doi
1720:doi
1716:345
1682:doi
1670:437
1634:hdl
1626:doi
1622:122
1594:doi
1590:280
1551:doi
1547:116
1510:doi
1479:doi
1475:277
1438:doi
1434:508
1400:doi
1368:doi
1364:273
1335:doi
1303:doi
1299:272
1240:doi
1236:277
1190:doi
288:End
187:End
90:OMA
66:MGI
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