308:
285:
182:
207:
314:
213:
31:
1206:
domain shows strong structural similarity with the N-terminal domains of syntaxin 1a, Sso1p, and Vam3p; despite a very low level of sequence similarity. SNARE functions essentially as a tether to hold the vesicle. The cytoplasmic regions of SNARE found on transport vesicles and target membranes
1251:
that contributes to the fusion of two membranes. More specifically, the N-terminal domain binds to the SNARE motif, and this intramolecular interaction decreases the rate of association with the partner SNARE. However the N terminal domain's function still remains to fully elucidated.
57:
2001:"Association of a novel PDZ domain-containing peripheral Golgi protein with the Q-SNARE (Q-soluble N-ethylmaleimide-sensitive fusion protein (NSF) attachment protein receptor) protein syntaxin 6"
2319:
2200:
Kim BY, Ueda M, Kominami E, Akagawa K, Kohsaka S, Akazawa C (November 2003). "Identification of mouse Vps16 and biochemical characterization of mammalian class C Vps complex".
3097:
321:
220:
1723:
Simonsen A, Lippé R, Christoforidis S, Gaullier JM, Brech A, Callaghan J, et al. (July 1998). "EEA1 links PI(3)K function to Rab5 regulation of endosome fusion".
3300:
1247:
SNAREs play a vital role in the trafficking of cell cargo. The vesicles fuse to the cell membrane with the help of SNARE proteins. The SNARE motifs form a
2958:
2312:
143:
2229:
Huynh H, Bottini N, Williams S, Cherepanov V, Musumeci L, Saito K, et al. (September 2004). "Control of vesicle fusion by a tyrosine phosphatase".
858:
839:
1955:"Syntaxin 7 complexes with mouse Vps10p tail interactor 1b, syntaxin 6, vesicle-associated membrane protein (VAMP)8, and VAMP7 in b16 melanoma cells"
1924:
Martín-Martín B, Nabokina SM, Blasi J, Lazo PA, Mollinedo F (October 2000). "Involvement of SNAP-23 and syntaxin 6 in human neutrophil exocytosis".
1421:
Martín-Martín B, Nabokina SM, Blasi J, Lazo PA, Mollinedo F (October 2000). "Involvement of SNAP-23 and syntaxin 6 in human neutrophil exocytosis".
1616:
Andersson B, Wentland MA, Ricafrente JY, Liu W, Gibbs RA (April 1996). "A "double adaptor" method for improved shotgun library construction".
2305:
1329:
1311:
1211:
to fusing two lipid bilayers. This is the way cell cargo is exchanged. This particular entry focuses on the N-terminal domain of
Syntaxin 6.
1349:"Co-expression of several human syntaxin genes in neutrophils and differentiating HL-60 cells: variant isoforms and detection of syntaxin 1"
3321:
1186:. It is part of the family, of target SNAREs (t-SNAREs). It is a vital aid to exporting and importing cell cargo through a process called
2523:
2336:
1207:
interact, then a four-helix coiled coil forms. This links the cell membrane and vesicles together in such a way that it overcomes the
1066:
307:
1073:
2273:
284:
1407:
3087:
1298:
1277:
1294:
1348:
206:
181:
54:
2811:
2285:
1273:
123:
2332:
1236:
1228:
1148:
2071:"A Golgi-associated PDZ domain protein modulates cystic fibrosis transmembrane regulator plasma membrane expression"
320:
219:
2486:
2481:
1232:
1195:
313:
212:
3267:
903:
131:
2752:
884:
2297:
1191:
2147:
Martinez-Arca S, Rudge R, Vacca M, Raposo G, Camonis J, Proux-Gillardeaux V, et al. (July 2003).
1187:
2160:
1732:
195:
110:
2823:
1179:
3037:
2988:
2949:
2890:
2291:
2279:
1224:
1199:
1024:
973:
3234:
2254:
1987:
1756:
1389:
155:
1813:"Vesicle-associated membrane protein 4 is implicated in trans-Golgi network vesicle trafficking"
1049:
1028:
998:
977:
1954:
1231:
three-helix bundle. Their exact function has not been determined, though it is known that they
2246:
2217:
2188:
2135:
2092:
2057:
2022:
1979:
1941:
1912:
1877:
1842:
1799:
1748:
1711:
1668:
1633:
1593:
1539:
1490:
1438:
1381:
1183:
103:
47:
3111:
1562:"Three-dimensional structure of the amino-terminal domain of syntaxin 6, a SNAP-25 C homolog"
2501:
2491:
2345:
2328:
2238:
2209:
2178:
2168:
2125:
2117:
2106:"Early/recycling endosomes-to-TGN transport involves two SNARE complexes and a Rab6 isoform"
2082:
2047:
2012:
1969:
1933:
1902:
1867:
1832:
1824:
1789:
1781:
1740:
1701:
1693:
1658:
1625:
1583:
1573:
1529:
1521:
1480:
1472:
1461:"Early/recycling endosomes-to-TGN transport involves two SNARE complexes and a Rab6 isoform"
1430:
1371:
1363:
400:
331:
275:
230:
3283:
3017:
2939:
2739:
2639:
2634:
2629:
2614:
2604:
2463:
2458:
2069:
Cheng J, Moyer BD, Milewski M, Loffing J, Ikeda M, Mickle JE, et al. (February 2002).
2594:
2511:
2363:
2354:
1768:
Wong SH, Xu Y, Zhang T, Griffiths G, Lowe SL, Subramaniam VN, et al. (January 1999).
1647:"A new syntaxin family member implicated in targeting of intracellular transport vesicles"
375:
151:
2164:
1736:
2130:
2105:
2104:
Mallard F, Tang BL, Galli T, Tenza D, Saint-Pol A, Yue X, et al. (February 2002).
1534:
1509:
1485:
1460:
1459:
Mallard F, Tang BL, Galli T, Tenza D, Saint-Pol A, Yue X, et al. (February 2002).
1220:
1208:
1172:
2183:
2148:
1953:
Wade N, Bryant NJ, Connolly LM, Simpson RJ, Luzio JP, Piper RC, James DE (June 2001).
1907:
1890:
1706:
1681:
1588:
1561:
773:
768:
763:
758:
753:
748:
743:
738:
733:
728:
723:
718:
702:
697:
692:
687:
682:
677:
672:
667:
662:
657:
652:
647:
642:
637:
632:
627:
622:
606:
601:
596:
591:
30:
3315:
3260:
2655:
2551:
2519:
1837:
1812:
1794:
1769:
578:
2258:
1991:
1393:
135:
3193:
2797:
2748:
2668:
1760:
393:
172:
1510:"Regulation of intracellular membrane trafficking and cell dynamics by syntaxin-6"
2149:"A dual mechanism controlling the localization and function of exocytic v-SNAREs"
1680:
Yu W, Andersson B, Worley KC, Muzny DM, Ding Y, Liu W, et al. (April 1997).
159:
2719:
2699:
1334:
National Center for
Biotechnology Information, U.S. National Library of Medicine
1316:
National Center for
Biotechnology Information, U.S. National Library of Medicine
1248:
2213:
2153:
Proceedings of the
National Academy of Sciences of the United States of America
1770:"GS32, a novel Golgi SNARE of 32 kDa, interacts preferentially with syntaxin 6"
1566:
Proceedings of the
National Academy of Sciences of the United States of America
476:
2865:
2860:
2855:
2403:
1203:
292:
189:
139:
1937:
1872:
1855:
1663:
1646:
1434:
1178:
is a soluble N-ethylmaleimide-sensitive factor attachment protein receptor (
3106:
2173:
803:
536:
414:
359:
346:
258:
245:
147:
2250:
2221:
2192:
2139:
2096:
2087:
2070:
2061:
2052:
2036:"Association of insulin-like growth factor 1 receptor with EHD1 and SNAP29"
2035:
2026:
2017:
2000:
1983:
1974:
1945:
1916:
1881:
1846:
1629:
1597:
1578:
1543:
1494:
1442:
1385:
2121:
1828:
1803:
1752:
1715:
1672:
1637:
1476:
1113:
1108:
3174:
2851:
2843:
2815:
2770:
2694:
2660:
2383:
1811:
Steegmaier M, Klumperman J, Foletti DL, Yoo JS, Scheller RH (June 1999).
1785:
1367:
1097:
948:
929:
1889:
Scales SJ, Chen YA, Yoo BY, Patel SM, Doung YC, Scheller RH (May 2000).
1525:
3201:
3179:
2714:
2472:
1697:
1376:
1129:
915:
870:
80:
76:
3276:
3271:
2779:
2775:
2496:
2476:
2376:
2371:
1152:
1081:
825:
2242:
1560:
Misura KM, Bock JB, Gonzalez LC, Scheller RH, Weis WI (July 2002).
3074:
3061:
3056:
3051:
3046:
3027:
3022:
3012:
3007:
3002:
2997:
2978:
2973:
2968:
2963:
2934:
2929:
2924:
2919:
2914:
2909:
2904:
2899:
2801:
2788:
2784:
2762:
2734:
2729:
2709:
2704:
2672:
2624:
2619:
2609:
2537:
2532:
2527:
2453:
2448:
2443:
2438:
2433:
2393:
2388:
1744:
1160:
1156:
1347:
Martín-Martín B, Nabokina SM, Lazo PA, Mollinedo F (March 1999).
788:
784:
3253:
3248:
3243:
3238:
3216:
3211:
3206:
3158:
3153:
3137:
3132:
3127:
2833:
2828:
2724:
2686:
2599:
2589:
2584:
2579:
2574:
2569:
2564:
2559:
2428:
2423:
2413:
2408:
2398:
1854:
Simonsen A, Gaullier JM, D'Arrigo A, Stenmark H (October 1999).
1136:
127:
2301:
1194:
to both syntaxin 1a and S25C, indicating similarity through
1856:"The Rab5 effector EEA1 interacts directly with syntaxin-6"
1508:
Jung JJ, Inamdar SM, Tiwari A, Choudhury A (August 2012).
1891:"SNAREs contribute to the specificity of membrane fusion"
1999:
Charest A, Lane K, McMahon K, Housman DE (August 2001).
383:
2034:
Rotem-Yehudar R, Galperin E, Horowitz M (August 2001).
548:
3227:
3192:
3167:
3146:
3120:
3096:
3036:
2987:
2948:
2889:
2882:
2875:
2842:
2810:
2761:
2685:
2648:
2550:
2510:
2362:
2353:
2344:
2202:
1042:
1017:
991:
966:
1290:
1288:
1286:
1269:
1267:
1265:
330:
229:
1555:
1553:
698:integral component of synaptic vesicle membrane
18:Protein-coding gene in the species Homo sapiens
1454:
1452:
1295:GRCm38: Ensembl release 89: ENSMUSG00000026470
1219:Members of this entry, which are found in the
2313:
8:
1235:the SNARE motif, as well as mediate various
1682:"Large-scale concatenation cDNA sequencing"
1274:GRCh38: Ensembl release 89: ENSG00000135823
2886:
2879:
2359:
2350:
2320:
2306:
2298:
1645:Bock JB, Lin RC, Scheller RH (July 1996).
799:
574:
371:
270:
167:
65:
2182:
2172:
2129:
2086:
2051:
2016:
1973:
1906:
1871:
1836:
1793:
1705:
1662:
1587:
1577:
1533:
1484:
1375:
1261:
734:retrograde transport, endosome to Golgi
20:
3301:vesicular transport protein disorders
335:
296:
291:
234:
193:
188:
7:
1190:. Its SNARE motif shows significant
1176:Syntaxin 6 N terminal protein domain
2075:The Journal of Biological Chemistry
2040:The Journal of Biological Chemistry
2005:The Journal of Biological Chemistry
1962:The Journal of Biological Chemistry
1860:The Journal of Biological Chemistry
1651:The Journal of Biological Chemistry
1223:of various SNARE proteins, adopt a
774:synaptic vesicle to endosome fusion
1039:
1014:
988:
963:
939:
920:
894:
875:
849:
830:
724:regulation of protein localization
553:
471:
409:
388:
14:
1132:that in humans is encoded by the
1239:involved in membrane-transport.
319:
312:
306:
283:
218:
211:
205:
180:
29:
1182:) found in endosomal transport
764:intracellular protein transport
648:perinuclear region of cytoplasm
1408:"Entrez Gene: STX6 syntaxin 6"
663:integral component of membrane
537:More reference expression data
1:
1908:10.1016/S0896-6273(00)81177-0
1817:Molecular Biology of the Cell
1774:Molecular Biology of the Cell
304:
203:
2333:vesicular transport proteins
1356:Journal of Leukocyte Biology
1237:protein-protein interactions
673:trans-Golgi network membrane
3322:Genes on human chromosome 1
2278:human gene location in the
2110:The Journal of Cell Biology
1465:The Journal of Cell Biology
3338:
2290:human gene details in the
2214:10.1016/j.bbrc.2003.10.030
759:vesicle-mediated transport
3296:
3083:
3070:
3038:Adaptor protein complex 4
2989:Adaptor protein complex 3
2950:Adaptor protein complex 2
2891:Adaptor protein complex 1
1330:"Mouse PubMed Reference:"
1312:"Human PubMed Reference:"
1196:evolutionary conservation
1167:N terminal protein domain
1112:
1107:
1103:
1096:
1080:
1074:Chr 1: 155.03 – 155.08 Mb
1067:Chr 1: 180.97 – 181.02 Mb
1061:
1046:
1021:
1010:
995:
970:
959:
946:
942:
927:
923:
914:
901:
897:
882:
878:
869:
856:
852:
837:
833:
824:
809:
802:
798:
782:
577:
573:
561:
556:
547:
534:
507:medullary collecting duct
483:
474:
421:
412:
382:
374:
370:
353:
340:
303:
282:
273:
269:
252:
239:
202:
179:
170:
166:
121:
118:
108:
101:
96:
73:
68:
51:
46:
41:
37:
28:
23:
3268:Vacuolar protein sorting
1938:10.1182/blood.V96.7.2574
1873:10.1074/jbc.274.41.28857
1664:10.1074/jbc.271.30.17961
1435:10.1182/blood.V96.7.2574
495:Rostral migratory stream
2174:10.1073/pnas.1431910100
1618:Analytical Biochemistry
1147:STX6 has been shown to
739:Golgi vesicle transport
653:clathrin-coated vesicle
491:internal carotid artery
487:external carotid artery
2088:10.1074/jbc.M110177200
2053:10.1074/jbc.M009913200
2018:10.1074/jbc.M104137200
1975:10.1074/jbc.M010838200
1630:10.1006/abio.1996.0138
1579:10.1073/pnas.132274599
754:Golgi ribbon formation
602:SNAP receptor activity
2122:10.1083/jcb.200110081
1829:10.1091/mbc.10.6.1957
1477:10.1083/jcb.200110081
719:endosome organization
457:primary visual cortex
1786:10.1091/mbc.10.1.119
1368:10.1002/jlb.65.3.397
298:Chromosome 1 (mouse)
196:Chromosome 1 (human)
69:List of PDB id codes
42:Available structures
2292:UCSC Genome Browser
2280:UCSC Genome Browser
2231:Nature Cell Biology
2165:2003PNAS..100.9011M
1737:1998Natur.394..494S
1526:10.1042/BSR20120006
769:endocytic recycling
703:endomembrane system
658:trans-Golgi network
511:endocardial cushion
499:conjunctival fornix
437:ganglionic eminence
433:gingival epithelium
3235:EHD protein family
1698:10.1101/gr.7.4.353
1514:Bioscience Reports
1202:of the syntaxin 6
904:ENSMUSG00000026470
712:Biological process
643:phagocytic vesicle
616:Cellular component
585:Molecular function
503:epithelium of lens
3309:
3308:
3292:
3291:
3188:
3187:
2883:Vesicle formation
2681:
2680:
2546:
2545:
1249:four-helix bundle
1227:consisting of an
1209:energetic barrier
1123:
1122:
1119:
1118:
1092:
1091:
1057:
1056:
1036:
1035:
1006:
1005:
985:
984:
955:
954:
936:
935:
910:
909:
891:
890:
865:
864:
846:
845:
794:
793:
744:protein transport
569:
568:
565:
564:
543:
542:
530:
529:
468:
467:
366:
365:
265:
264:
92:
91:
88:
87:
52:Ortholog search:
3329:
2887:
2880:
2360:
2351:
2346:Synaptic vesicle
2329:Membrane protein
2322:
2315:
2308:
2299:
2262:
2225:
2196:
2186:
2176:
2143:
2133:
2100:
2090:
2065:
2055:
2046:(35): 33054–60.
2030:
2020:
2011:(31): 29456–65.
1995:
1977:
1959:
1949:
1920:
1910:
1885:
1875:
1866:(41): 28857–60.
1850:
1840:
1807:
1797:
1764:
1719:
1709:
1676:
1666:
1641:
1602:
1601:
1591:
1581:
1557:
1548:
1547:
1537:
1505:
1499:
1498:
1488:
1456:
1447:
1446:
1418:
1412:
1411:
1404:
1398:
1397:
1379:
1353:
1344:
1338:
1337:
1326:
1320:
1319:
1308:
1302:
1292:
1281:
1271:
1188:cell trafficking
1105:
1104:
1076:
1069:
1052:
1040:
1031:
1015:
1011:RefSeq (protein)
1001:
989:
980:
964:
940:
921:
895:
876:
850:
831:
800:
693:synaptic vesicle
597:syntaxin binding
575:
554:
539:
479:
477:Top expressed in
472:
461:cartilage tissue
441:Brodmann area 23
429:endothelial cell
425:secondary oocyte
417:
415:Top expressed in
410:
389:
372:
362:
349:
338:
323:
316:
310:
299:
287:
271:
261:
248:
237:
222:
215:
209:
198:
184:
168:
162:
160:STX6 - orthologs
113:
106:
83:
66:
60:
39:
38:
33:
21:
3337:
3336:
3332:
3331:
3330:
3328:
3327:
3326:
3312:
3311:
3310:
3305:
3304:
3288:
3223:
3184:
3163:
3142:
3116:
3092:
3079:
3066:
3032:
2983:
2944:
2876:Other/ungrouped
2871:
2838:
2806:
2757:
2677:
2663:
2644:
2542:
2506:
2340:
2326:
2270:
2265:
2243:10.1038/ncb1164
2228:
2199:
2146:
2103:
2068:
2033:
1998:
1968:(23): 19820–7.
1957:
1952:
1923:
1888:
1853:
1810:
1767:
1731:(6692): 494–8.
1722:
1686:Genome Research
1679:
1657:(30): 17961–5.
1644:
1615:
1611:
1609:Further reading
1606:
1605:
1559:
1558:
1551:
1507:
1506:
1502:
1458:
1457:
1450:
1420:
1419:
1415:
1406:
1405:
1401:
1351:
1346:
1345:
1341:
1328:
1327:
1323:
1310:
1309:
1305:
1293:
1284:
1272:
1263:
1258:
1245:
1217:
1169:
1145:
1114:View/Edit Mouse
1109:View/Edit Human
1072:
1065:
1062:Location (UCSC)
1048:
1027:
1023:
997:
976:
972:
885:ENSG00000135823
778:
729:vesicle docking
707:
678:Golgi apparatus
628:plasma membrane
611:
592:protein binding
535:
526:
521:
517:
513:
509:
505:
501:
497:
493:
489:
475:
464:
459:
455:
451:
447:
443:
439:
435:
431:
427:
413:
357:
344:
336:
326:
325:
324:
317:
297:
274:Gene location (
256:
243:
235:
225:
224:
223:
216:
194:
171:Gene location (
122:
109:
102:
75:
53:
19:
12:
11:
5:
3335:
3333:
3325:
3324:
3314:
3313:
3307:
3306:
3297:
3294:
3293:
3290:
3289:
3287:
3286:
3280:
3279:
3274:
3264:
3263:
3261:Sorting nexins
3257:
3256:
3251:
3246:
3241:
3231:
3229:
3225:
3224:
3222:
3221:
3220:
3219:
3214:
3209:
3198:
3196:
3190:
3189:
3186:
3185:
3183:
3182:
3177:
3171:
3169:
3165:
3164:
3162:
3161:
3156:
3150:
3148:
3144:
3143:
3141:
3140:
3135:
3130:
3124:
3122:
3118:
3117:
3115:
3114:
3109:
3103:
3101:
3094:
3093:
3091:
3090:
3084:
3081:
3080:
3078:
3077:
3071:
3068:
3067:
3065:
3064:
3059:
3054:
3049:
3043:
3041:
3034:
3033:
3031:
3030:
3025:
3020:
3015:
3010:
3005:
3000:
2994:
2992:
2985:
2984:
2982:
2981:
2976:
2971:
2966:
2961:
2955:
2953:
2946:
2945:
2943:
2942:
2937:
2932:
2927:
2922:
2917:
2912:
2907:
2902:
2896:
2894:
2884:
2877:
2873:
2872:
2870:
2869:
2863:
2858:
2848:
2846:
2840:
2839:
2837:
2836:
2831:
2826:
2820:
2818:
2808:
2807:
2805:
2804:
2794:
2793:
2792:
2791:
2782:
2767:
2765:
2759:
2758:
2756:
2755:
2745:
2744:
2743:
2742:
2737:
2732:
2727:
2722:
2717:
2712:
2707:
2702:
2691:
2689:
2683:
2682:
2679:
2678:
2676:
2675:
2665:
2664:
2658:
2652:
2650:
2646:
2645:
2643:
2642:
2637:
2632:
2627:
2622:
2617:
2612:
2607:
2602:
2597:
2592:
2587:
2582:
2577:
2572:
2567:
2562:
2556:
2554:
2548:
2547:
2544:
2543:
2541:
2540:
2535:
2530:
2516:
2514:
2508:
2507:
2505:
2504:
2499:
2494:
2489:
2484:
2479:
2469:
2468:
2467:
2466:
2461:
2456:
2451:
2446:
2441:
2436:
2431:
2426:
2421:
2416:
2411:
2406:
2401:
2396:
2391:
2380:
2379:
2374:
2368:
2366:
2357:
2348:
2342:
2341:
2327:
2325:
2324:
2317:
2310:
2302:
2296:
2295:
2283:
2269:
2268:External links
2266:
2264:
2263:
2226:
2197:
2159:(15): 9011–6.
2144:
2101:
2066:
2031:
1996:
1950:
1932:(7): 2574–83.
1921:
1886:
1851:
1823:(6): 1957–72.
1808:
1765:
1720:
1677:
1642:
1612:
1610:
1607:
1604:
1603:
1572:(14): 9184–9.
1549:
1500:
1448:
1429:(7): 2574–83.
1413:
1399:
1362:(3): 397–406.
1339:
1321:
1303:
1282:
1260:
1259:
1257:
1254:
1244:
1241:
1221:amino terminus
1216:
1213:
1173:protein domain
1168:
1165:
1144:
1141:
1121:
1120:
1117:
1116:
1111:
1101:
1100:
1094:
1093:
1090:
1089:
1087:
1085:
1078:
1077:
1070:
1063:
1059:
1058:
1055:
1054:
1044:
1043:
1037:
1034:
1033:
1019:
1018:
1012:
1008:
1007:
1004:
1003:
993:
992:
986:
983:
982:
968:
967:
961:
957:
956:
953:
952:
944:
943:
937:
934:
933:
925:
924:
918:
912:
911:
908:
907:
899:
898:
892:
889:
888:
880:
879:
873:
867:
866:
863:
862:
854:
853:
847:
844:
843:
835:
834:
828:
822:
821:
816:
811:
807:
806:
796:
795:
792:
791:
780:
779:
777:
776:
771:
766:
761:
756:
751:
749:vesicle fusion
746:
741:
736:
731:
726:
721:
715:
713:
709:
708:
706:
705:
700:
695:
690:
685:
680:
675:
670:
668:Golgi membrane
665:
660:
655:
650:
645:
640:
638:early endosome
635:
630:
625:
619:
617:
613:
612:
610:
609:
604:
599:
594:
588:
586:
582:
581:
571:
570:
567:
566:
563:
562:
559:
558:
551:
545:
544:
541:
540:
532:
531:
528:
527:
525:
524:
520:
519:left lung lobe
516:
512:
508:
504:
500:
496:
492:
488:
484:
481:
480:
469:
466:
465:
463:
462:
458:
454:
450:
446:
442:
438:
434:
430:
426:
422:
419:
418:
406:
405:
397:
386:
380:
379:
376:RNA expression
368:
367:
364:
363:
355:
351:
350:
342:
339:
334:
328:
327:
318:
311:
305:
301:
300:
295:
289:
288:
280:
279:
267:
266:
263:
262:
254:
250:
249:
241:
238:
233:
227:
226:
217:
210:
204:
200:
199:
192:
186:
185:
177:
176:
164:
163:
120:
116:
115:
107:
99:
98:
94:
93:
90:
89:
86:
85:
71:
70:
62:
61:
50:
44:
43:
35:
34:
26:
25:
17:
13:
10:
9:
6:
4:
3:
2:
3334:
3323:
3320:
3319:
3317:
3303:
3302:
3295:
3285:
3282:
3281:
3278:
3275:
3273:
3269:
3266:
3265:
3262:
3259:
3258:
3255:
3252:
3250:
3247:
3245:
3242:
3240:
3236:
3233:
3232:
3230:
3226:
3218:
3215:
3213:
3210:
3208:
3205:
3204:
3203:
3200:
3199:
3197:
3195:
3191:
3181:
3178:
3176:
3173:
3172:
3170:
3166:
3160:
3157:
3155:
3152:
3151:
3149:
3145:
3139:
3136:
3134:
3131:
3129:
3126:
3125:
3123:
3119:
3113:
3110:
3108:
3105:
3104:
3102:
3099:
3095:
3089:
3086:
3085:
3082:
3076:
3073:
3072:
3069:
3063:
3060:
3058:
3055:
3053:
3050:
3048:
3045:
3044:
3042:
3039:
3035:
3029:
3026:
3024:
3021:
3019:
3016:
3014:
3011:
3009:
3006:
3004:
3001:
2999:
2996:
2995:
2993:
2990:
2986:
2980:
2977:
2975:
2972:
2970:
2967:
2965:
2962:
2960:
2957:
2956:
2954:
2951:
2947:
2941:
2938:
2936:
2933:
2931:
2928:
2926:
2923:
2921:
2918:
2916:
2913:
2911:
2908:
2906:
2903:
2901:
2898:
2897:
2895:
2892:
2888:
2885:
2881:
2878:
2874:
2867:
2864:
2862:
2859:
2857:
2853:
2850:
2849:
2847:
2845:
2841:
2835:
2832:
2830:
2827:
2825:
2822:
2821:
2819:
2817:
2813:
2809:
2803:
2799:
2796:
2795:
2790:
2786:
2783:
2781:
2777:
2774:
2773:
2772:
2769:
2768:
2766:
2764:
2760:
2754:
2750:
2747:
2746:
2741:
2738:
2736:
2733:
2731:
2728:
2726:
2723:
2721:
2718:
2716:
2713:
2711:
2708:
2706:
2703:
2701:
2698:
2697:
2696:
2693:
2692:
2690:
2688:
2684:
2674:
2670:
2667:
2666:
2662:
2659:
2657:
2656:Synaptophysin
2654:
2653:
2651:
2647:
2641:
2638:
2636:
2633:
2631:
2628:
2626:
2623:
2621:
2618:
2616:
2613:
2611:
2608:
2606:
2603:
2601:
2598:
2596:
2593:
2591:
2588:
2586:
2583:
2581:
2578:
2576:
2573:
2571:
2568:
2566:
2563:
2561:
2558:
2557:
2555:
2553:
2552:Synaptotagmin
2549:
2539:
2536:
2534:
2531:
2529:
2525:
2521:
2520:Synaptobrevin
2518:
2517:
2515:
2513:
2509:
2503:
2500:
2498:
2495:
2493:
2490:
2488:
2485:
2483:
2480:
2478:
2474:
2471:
2470:
2465:
2462:
2460:
2457:
2455:
2452:
2450:
2447:
2445:
2442:
2440:
2437:
2435:
2432:
2430:
2427:
2425:
2422:
2420:
2417:
2415:
2412:
2410:
2407:
2405:
2402:
2400:
2397:
2395:
2392:
2390:
2387:
2386:
2385:
2382:
2381:
2378:
2375:
2373:
2370:
2369:
2367:
2365:
2361:
2358:
2356:
2352:
2349:
2347:
2343:
2338:
2334:
2330:
2323:
2318:
2316:
2311:
2309:
2304:
2303:
2300:
2293:
2289:
2288:
2284:
2281:
2277:
2276:
2272:
2271:
2267:
2260:
2256:
2252:
2248:
2244:
2240:
2236:
2232:
2227:
2223:
2219:
2215:
2211:
2208:(3): 577–82.
2207:
2203:
2198:
2194:
2190:
2185:
2180:
2175:
2170:
2166:
2162:
2158:
2154:
2150:
2145:
2141:
2137:
2132:
2127:
2123:
2119:
2116:(4): 653–64.
2115:
2111:
2107:
2102:
2098:
2094:
2089:
2084:
2081:(5): 3520–9.
2080:
2076:
2072:
2067:
2063:
2059:
2054:
2049:
2045:
2041:
2037:
2032:
2028:
2024:
2019:
2014:
2010:
2006:
2002:
1997:
1993:
1989:
1985:
1981:
1976:
1971:
1967:
1963:
1956:
1951:
1947:
1943:
1939:
1935:
1931:
1927:
1922:
1918:
1914:
1909:
1904:
1901:(2): 457–64.
1900:
1896:
1892:
1887:
1883:
1879:
1874:
1869:
1865:
1861:
1857:
1852:
1848:
1844:
1839:
1834:
1830:
1826:
1822:
1818:
1814:
1809:
1805:
1801:
1796:
1791:
1787:
1783:
1780:(1): 119–34.
1779:
1775:
1771:
1766:
1762:
1758:
1754:
1750:
1746:
1745:10.1038/28879
1742:
1738:
1734:
1730:
1726:
1721:
1717:
1713:
1708:
1703:
1699:
1695:
1691:
1687:
1683:
1678:
1674:
1670:
1665:
1660:
1656:
1652:
1648:
1643:
1639:
1635:
1631:
1627:
1624:(1): 107–13.
1623:
1619:
1614:
1613:
1608:
1599:
1595:
1590:
1585:
1580:
1575:
1571:
1567:
1563:
1556:
1554:
1550:
1545:
1541:
1536:
1531:
1527:
1523:
1520:(4): 383–91.
1519:
1515:
1511:
1504:
1501:
1496:
1492:
1487:
1482:
1478:
1474:
1471:(4): 653–64.
1470:
1466:
1462:
1455:
1453:
1449:
1444:
1440:
1436:
1432:
1428:
1424:
1417:
1414:
1409:
1403:
1400:
1395:
1391:
1387:
1383:
1378:
1373:
1369:
1365:
1361:
1357:
1350:
1343:
1340:
1335:
1331:
1325:
1322:
1317:
1313:
1307:
1304:
1300:
1296:
1291:
1289:
1287:
1283:
1279:
1275:
1270:
1268:
1266:
1262:
1255:
1253:
1250:
1242:
1240:
1238:
1234:
1230:
1226:
1222:
1214:
1212:
1210:
1205:
1201:
1197:
1193:
1189:
1185:
1181:
1177:
1174:
1166:
1164:
1162:
1158:
1154:
1150:
1142:
1140:
1138:
1135:
1131:
1127:
1115:
1110:
1106:
1102:
1099:
1095:
1088:
1086:
1083:
1079:
1075:
1071:
1068:
1064:
1060:
1053:
1051:
1045:
1041:
1038:
1032:
1030:
1026:
1020:
1016:
1013:
1009:
1002:
1000:
994:
990:
987:
981:
979:
975:
969:
965:
962:
960:RefSeq (mRNA)
958:
951:
950:
945:
941:
938:
932:
931:
926:
922:
919:
917:
913:
906:
905:
900:
896:
893:
887:
886:
881:
877:
874:
872:
868:
861:
860:
855:
851:
848:
842:
841:
836:
832:
829:
827:
823:
820:
817:
815:
812:
808:
805:
801:
797:
790:
786:
781:
775:
772:
770:
767:
765:
762:
760:
757:
755:
752:
750:
747:
745:
742:
740:
737:
735:
732:
730:
727:
725:
722:
720:
717:
716:
714:
711:
710:
704:
701:
699:
696:
694:
691:
689:
686:
684:
681:
679:
676:
674:
671:
669:
666:
664:
661:
659:
656:
654:
651:
649:
646:
644:
641:
639:
636:
634:
633:SNARE complex
631:
629:
626:
624:
621:
620:
618:
615:
614:
608:
607:SNARE binding
605:
603:
600:
598:
595:
593:
590:
589:
587:
584:
583:
580:
579:Gene ontology
576:
572:
560:
555:
552:
550:
546:
538:
533:
523:Gonadal ridge
522:
518:
515:hair follicle
514:
510:
506:
502:
498:
494:
490:
486:
485:
482:
478:
473:
470:
460:
456:
452:
448:
445:skin of thigh
444:
440:
436:
432:
428:
424:
423:
420:
416:
411:
408:
407:
404:
402:
398:
396:
395:
391:
390:
387:
385:
381:
377:
373:
369:
361:
356:
352:
348:
343:
333:
329:
322:
315:
309:
302:
294:
290:
286:
281:
277:
272:
268:
260:
255:
251:
247:
242:
232:
228:
221:
214:
208:
201:
197:
191:
187:
183:
178:
174:
169:
165:
161:
157:
153:
149:
145:
141:
137:
133:
129:
125:
117:
112:
105:
100:
95:
84:
82:
78:
72:
67:
64:
63:
59:
56:
49:
45:
40:
36:
32:
27:
22:
16:
3298:
3194:Small GTPase
2798:Small GTPase
2749:Small GTPase
2715:COPD/Archain
2669:Small GTPase
2418:
2286:
2274:
2237:(9): 831–9.
2234:
2230:
2205:
2201:
2156:
2152:
2113:
2109:
2078:
2074:
2043:
2039:
2008:
2004:
1965:
1961:
1929:
1925:
1898:
1894:
1863:
1859:
1820:
1816:
1777:
1773:
1728:
1724:
1692:(4): 353–8.
1689:
1685:
1654:
1650:
1621:
1617:
1569:
1565:
1517:
1513:
1503:
1468:
1464:
1426:
1422:
1416:
1402:
1359:
1355:
1342:
1333:
1324:
1315:
1306:
1246:
1229:antiparallel
1218:
1175:
1170:
1146:
1143:Interactions
1133:
1125:
1124:
1047:
1025:NP_001273139
1022:
996:
974:NM_001286210
971:
947:
928:
902:
883:
857:
838:
818:
813:
399:
392:
358:155,084,002
345:155,034,461
257:181,023,121
244:180,972,712
119:External IDs
114:, syntaxin 6
74:
15:
1377:10261/59829
683:nucleoplasm
449:skin of hip
337:1|1 G3
97:Identifiers
1301:, May 2017
1280:, May 2017
1256:References
1204:N-terminal
1126:Syntaxin-6
403:(ortholog)
140:HomoloGene
3299:See also
1225:structure
1215:Structure
1200:structure
1050:NP_067408
1029:NP_005810
999:NM_021433
978:NM_005819
804:Orthologs
148:GeneCards
3316:Category
3175:Retromer
2852:Caveolin
2844:Caveolae
2816:Clathrin
2771:Coatomer
2695:Coatomer
2661:Synapsin
2384:Syntaxin
2259:25311826
2251:15322554
2222:14623309
2193:12853575
2140:11839770
2097:11707463
2062:11423532
2027:11384996
1992:38183181
1984:11278762
1946:11001914
1917:10839363
1882:10506127
1847:10359608
1598:12082176
1544:22489884
1495:11839770
1443:11001914
1394:18988377
1386:10080545
1297:–
1276:–
1243:Function
1233:regulate
1192:homology
1184:vesicles
1149:interact
1098:Wikidata
783:Sources:
623:membrane
453:monocyte
3202:Dynamin
3147:BLOC-3:
3121:BLOC-2:
3112:BLOC153
2512:R-SNARE
2473:Munc-18
2364:Q-SNARE
2161:Bibcode
2131:2174079
1804:9880331
1761:4305220
1753:9697774
1733:Bibcode
1716:9110174
1673:8663448
1638:8619474
1535:3392101
1486:2174079
1299:Ensembl
1278:Ensembl
1130:protein
916:UniProt
871:Ensembl
810:Species
789:QuickGO
688:cytosol
378:pattern
136:1926235
104:Aliases
3277:VPS33B
3272:VPS13B
3168:Coats:
3107:DTNBP1
3098:BLOC-1
2780:SEC24A
2776:SEC23A
2502:STXBP6
2497:STXBP5
2492:STXBP4
2487:STXBP3
2482:STXBP2
2477:STXBP1
2377:SNAP29
2372:SNAP25
2257:
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2191:
2184:166429
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1153:SNAP23
1084:search
1082:PubMed
949:Q9JKK1
930:O43752
826:Entrez
549:BioGPS
236:1q25.3
144:115622
128:603944
3284:SYNRG
3228:Other
3180:TIP47
3075:LMAN1
3062:AP4S1
3057:AP4M1
3052:AP4E1
3047:AP4B1
3028:AP3S2
3023:AP3S1
3018:AP3M2
3013:AP3M1
3008:AP3D1
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2998:AP3B1
2979:AP2S1
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2920:AP1M1
2915:AP1G2
2910:AP1G1
2905:AP1B1
2900:AP1AR
2802:SAR1A
2789:SEC31
2785:SEC13
2763:COPII
2740:COPZ2
2735:COPZ1
2730:COPG2
2710:COPB2
2705:COPB1
2673:RAB3A
2649:Other
2640:SYT17
2635:SYT16
2630:SYT15
2625:SYT14
2620:SYT13
2615:SYT12
2610:SYT11
2605:SYT10
2538:VAMP3
2533:VAMP2
2528:VAMP1
2464:STX19
2459:STX18
2454:STX17
2449:STX16
2444:STX12
2439:STX11
2434:STX10
2394:STX1B
2389:STX1A
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2255:S2CID
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1838:25394
1795:25158
1757:S2CID
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1390:S2CID
1352:(PDF)
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341:Start
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2861:CAV2
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2834:CLTC
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2720:COPE
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2687:COPI
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2189:PMID
2136:PMID
2093:PMID
2058:PMID
2023:PMID
1980:PMID
1942:PMID
1913:PMID
1878:PMID
1843:PMID
1800:PMID
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1712:PMID
1669:PMID
1634:PMID
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2157:100
2126:PMC
2118:doi
2114:156
2083:doi
2079:277
2048:doi
2044:276
2013:doi
2009:276
1970:doi
1966:276
1934:doi
1903:doi
1868:doi
1864:274
1833:PMC
1825:doi
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1741:doi
1729:394
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1659:doi
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1626:doi
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1481:PMC
1473:doi
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1431:doi
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557:n/a
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