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Additionally, in many strains of the yeast, it is found along with another virus called the M virus (or "M dsRNA", "Saccharomyces cerevisiae killer virus"), known to encode the killer toxin in many
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strains which confers the ability to kill neighboring sensitive cells that do not harbor the virus. It is indeed for this reason the virus is referred to as a
338:"Relationships and Evolution of Double-Stranded RNA Totiviruses of Yeasts Inferred from Analysis of L-A-2 and L-BC Variants in Wine Yeast Strain Populations"
450:"New Insights into the Genome Organization of Yeast Killer Viruses Based on "Atypical" Killer Strains Characterized by High-Throughput Sequencing"
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There are numerous apparently unrelated M dsRNAs that use L-A, their only similarity being their genome organization. The family of
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Classification and nomenclature of viruses. Fifth report of the
International Committee on Taxonomy of Viruses
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253:'s dependence on it for its own survival and replication. (More recently, the M dsRNA is described as a
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227:. Its discovery in the 1970s was the main starting point of research on yeast virology. It is a ~4.6
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Ramírez, M; Velázquez, R; López-Piñeiro, A; Naranjo, B; Roig, F; Llorens, C (19 September 2017).
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Replication cycle of L-A helper, shown at bottom, and M28 (K28) killer viruses in
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ScV-L-A capsid protein structure and homodimer of the gag capsid protein
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Francki, R.I.B.; Fauquet, C.M.; Knudson, D.L.; Brown, F., eds. (1991).
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in general helps M-type dsRNAs in a wide variety of yeasts.
398:"Yeast viral killer toxins: lethality and self-protection"
257:.) A yeast lineage with a M/killer virus is known as a "
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with no extracellular phase and so is inherited through
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Rodríguez-Cousiño, Nieves; Esteban, Rosa (2017-02-15).
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Schmitt, Manfred J.; Breinig, Frank (March 10, 2006).
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International
Committee on Taxonomy of Viruses (ICTV)
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296:. Archives of Virology Supplementum 2.
221:family of viruses found primarily in
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183:Saccharomyces cerevisiae virus ScV1
540:Saccharomyces cerevisiae virus L-A
510:Saccharomyces cerevisiae virus L-A
208:Saccharomyces cerevisiae virus L-A
160:Saccharomyces cerevisiae virus L-A
23:Saccharomyces cerevisiae virus L-A
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236:vertical cytoplasmic transmission
178:Saccharomyces cerevisiae virus LA
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402:Nature Reviews Microbiology
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232:double-stranded RNA virus
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224:Saccharomyces cerevisiae
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467:10.3390/toxins9090292
215:, is a member of the
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362:10.1128/AEM.02991-16
44:Virus classification
415:10.1038/nrmicro1347
354:2017ApEnM..83E2991R
317:. 5 September 1984
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616:Totiviridae
534:Wikispecies
321:10 February
267:Totiviridae
218:Totiviridae
135:Totiviridae
610:Categories
460:(9): 292.
274:References
154:Species:
147:Totivirus
82:Kingdom:
75:Riboviria
580:11460721
525:Q7396598
519:Wikidata
486:28925975
432:24668951
424:16489348
380:27940540
169:Synonyms
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371:5288835
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251:genome
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575:IRMNG
554:4TWCX
428:S2CID
348:(4).
311:(PDF)
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68:Realm
61:Virus
588:NCBI
482:PMID
420:PMID
376:PMID
323:2020
562:EoL
549:CoL
472:PMC
462:doi
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366:PMC
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