51:
196:
from blood, mucous membranes, or skin biopsy; however, these are often negative. Skin biopsy may show separation of the superficial layer of the epidermis (intraepidermal separation), differentiating SSSS from TEN, wherein the separation occurs at the dermo-epidermal junction (subepidermal
124:
Children with SSSS may exhibit fussiness or irritability, tiredness, fever, redness of the skin, easily broken fluid-filled blisters that leave an area of moist, tender, painful skin, and large sheets of the top layer of skin that easily peel away.
641:
626:
264:
In 1885, Nil
Filatow, and in 1894, Clement Dukes, described an exanthematous disease which they thought to be a form of rubella, but in 1900, Dukes identified it to be a separate entity which came to be known by the names
287:
261:
The clinical features were first described in 1878 by Baron
Gottfried Ritter von Rittershain, who observed 297 cases among children in a single Czechoslovakian children's home over a 10-year period.
357:
755:
249:
The prognosis of SSSS in children is excellent, with complete resolution within 10 days of treatment, and without significant scarring. However, SSSS must be differentiated carefully from
1590:
253:, which carries a poor prognosis. The prognosis in adults is generally much worse, and depends upon various factors such as time to treatment, host immunity, and comorbidities.
1860:
205:
The mainstay of treatment for SSSS is supportive care along with eradication of the primary infection. Conservative measures include rehydration, antipyretics (e.g.,
2611:
748:
273:
caused by staphylococcal exotoxin after Keith Powell proposed equating it with the condition currently known as staphylococcal scalded skin syndrome in 1979.
1583:
1176:
486:
Powell, KR (January 1979). "Filatow-Dukes' disease. Epidermolytic toxin-producing staphylococci as the etiologic agent of the fourth childhood exanthem".
101:
The disease presents with the widespread formation of fluid-filled blisters that are thin walled and easily ruptured, and the patient can be positive for
2575:
2162:
741:
1670:
1680:
1576:
1032:
1955:
2616:
1894:
316:
105:. Ritter's disease of the newborn is the most severe form of SSSS, with similar signs and symptoms. SSSS often includes a widespread painful
2073:
362:
2523:
1868:
2055:
332:
2481:
2219:
2078:
1981:
1402:
783:
269:, Filatov's disease, or fourth disease. Although Dukes identified it as a separate entity, it is thought not to be different from
1889:
1876:
2387:
1963:
1007:
987:
955:
936:
2128:
1950:
1904:
1815:
1805:
2232:
2152:
2098:
910:
2540:
2068:
1909:
1693:
1545:
1219:
828:
282:
2606:
2560:
2181:
2093:
927:
733:
2580:
2382:
1205:
416:
Dukes, Clement (30 June 1900). "On the confusion of two different diseases under the name of rubella (rose-rash)".
250:
118:
2108:
1884:
960:
2377:
2083:
2050:
1760:
1675:
1626:
1440:
1434:
1141:
1048:
1001:
847:
656:
2508:
2308:
2045:
2020:
1940:
1391:
1102:
897:
2088:
2040:
2030:
2025:
1914:
1599:
1497:
1290:
949:
904:
853:
721:
197:
separation). SSSS may be difficult to distinguish from toxic epidermal necrolysis and pustular psoriasis.
2535:
2513:
2426:
1739:
1518:
1511:
1350:
1160:
1096:
871:
89:
2570:
2239:
2228:
1855:
1845:
1645:
1524:
1503:
1171:
1110:
890:
883:
2452:
2447:
2357:
2283:
2273:
2247:
2243:
2118:
1924:
1835:
1607:
1066:
1026:
876:
779:
645:
2503:
2414:
1825:
1810:
1800:
1364:
1247:
589:
468:
181:
173:
164:. One of the exotoxins is encoded on the bacterial chromosome, while the other is encoded on a
102:
2528:
2208:
1919:
1536:
1267:
1091:
1061:
696:
667:
581:
542:
522:
503:
460:
398:
312:
266:
63:
2565:
2486:
2300:
2268:
1488:
573:
534:
495:
452:
425:
388:
177:
129:
42:
2459:
2347:
2171:
2103:
2010:
1830:
1709:
1261:
975:
802:
128:
The condition is most common in children under 6 years, but can be seen in adults who are
499:
50:
2585:
2464:
2367:
2197:
2063:
2005:
1990:
1850:
1781:
1419:
650:
133:
117:
might be present. Perioral crusting and fissuring are seen early in the course. Unlike
110:
577:
538:
456:
429:
2600:
2545:
2362:
2258:
2214:
1899:
1698:
1656:
1056:
965:
818:
393:
376:
270:
222:
17:
593:
472:
2550:
2476:
2372:
2144:
2035:
2015:
1820:
1734:
1397:
1082:
707:
213:), management of thermal burns, and stabilization. Parenteral antibiotics to cover
169:
114:
106:
661:
2555:
2263:
2157:
2123:
2113:
1945:
1755:
1725:
1551:
1326:
1296:
710:
691:
238:
210:
180:
layers together, similar to the pathophysiology of the autoimmune skin disease,
84:
68:
672:
2443:
2438:
1766:
1716:
1689:
1479:
1464:
1453:
1316:
1197:
1125:
970:
944:
770:
234:
153:
2433:
2278:
2202:
2148:
1616:
1424:
1331:
1188:
1151:
996:
774:
766:
702:
635:
230:
226:
206:
161:
585:
464:
402:
546:
192:
SSSS is a clinical diagnosis. This is sometimes confirmed by isolation of
2518:
2469:
2332:
2327:
2176:
1665:
1640:
1568:
1356:
1280:
1237:
1130:
837:
807:
716:
507:
149:
145:
2498:
2409:
2337:
2253:
1840:
1370:
1253:
793:
165:
618:
523:"Staphylococcal scalded skin syndrome: the expanded clinical syndrome"
443:
Weisse, Martin E (31 December 2000). "The fourth disease, 1900-2000".
375:
Mockenhaupt M, Idzko M, Grosber M, Schöpf E, Norgauer J (April 2005).
160:
and cause detachment within the epidermal layer, by breaking down the
2493:
630:
561:
2352:
377:"Epidemiology of staphylococcal scalded skin syndrome in Germany"
2421:
2342:
1572:
737:
560:
Morens, David M; Katz, Alan R; Melish, Marian E (31 May 2001).
241:
is sometimes also used because of its inhibition of exotoxins.
288:
List of conditions caused by problems with junctional proteins
225:, so are penicillin resistant. Therefore, treatment with
608:
2400:
2320:
2299:
2190:
2137:
1998:
1989:
1980:
1933:
1789:
1780:
1748:
1723:
1707:
1654:
1624:
1615:
1606:
1535:
1487:
1478:
1451:
1417:
1381:
1340:
1324:
1315:
1278:
1235:
1187:
1150:
1139:
1124:
1080:
1047:
1018:
986:
935:
926:
864:
836:
827:
816:
801:
792:
682:
612:
62:
58:
37:
32:
41:Pemphigus neonatorum, Ritter's disease, localized
109:, often involving the face, diaper, and other
1584:
749:
8:
168:. These exotoxins are proteases that cleave
307:Rapini RP, Bolognia JL, Jorizzo JL (2007).
2576:Recurrent toxin-mediated perineal erythema
1995:
1986:
1862:Mycobacterium avium–intracellulare complex
1786:
1621:
1612:
1591:
1577:
1569:
1484:
1337:
1321:
1147:
1136:
932:
833:
824:
813:
798:
756:
742:
734:
609:
49:
29:
1671:Cutaneous group B streptococcal infection
392:
488:American Journal of Diseases of Children
217:should be administered. Most strains of
1033:Cutaneous Streptococcus iniae infection
299:
2612:Bacterium-related cutaneous conditions
333:"Staphylococcal Scalded Skin Syndrome"
1895:Rapid growing mycobacterium infection
521:Melish, ME; Glasgow, LA (June 1971).
121:, SSSS spares the mucous membranes.
7:
2074:Human granulocytotropic anaplasmosis
1636:Staphylococcal scalded skin syndrome
1167:Staphylococcal scalded skin syndrome
562:"The fourth disease, 1900–1881, RIP"
500:10.1001/archpedi.1979.02130010094020
77:Staphylococcal scalded skin syndrome
33:Staphylococcal scalded skin syndrome
2524:Chronic undermining burrowing ulcer
25:
2482:Superficial pustular folliculitis
2079:Human monocytotropic ehrlichiosis
1403:Clostridial necrotizing enteritis
156:) A and B, which are released by
1890:Primary inoculation tuberculosis
394:10.1111/j.0022-202X.2005.23642.x
2388:Gram-negative toe web infection
1964:Group JK corynebacterium sepsis
1008:Group B streptococcal infection
956:Group A streptococcal infection
2129:Ehrlichiosis ewingii infection
1951:Cutaneous diphtheria infection
1905:Tuberculosis cutis orificialis
1816:Borderline tuberculoid leprosy
1806:Borderline lepromatous leprosy
1:
2153:Primary gonococcal dermatitis
2099:Flinders Island spotted fever
578:10.1016/S0140-6736(00)05151-5
539:10.1016/S0022-3476(71)80425-0
457:10.1016/S0140-6736(00)03623-0
430:10.1016/S0140-6736(00)65681-7
2617:Syndromes caused by microbes
2541:Blistering distal dactylitis
2069:Rocky Mountain spotted fever
1957:Arcanobacterium haemolyticum
1910:Tuberculosis verrucosa cutis
1694:Chronic recurrent erysipelas
1546:Erysipelothrix rhusiopathiae
363:Dorland's Medical Dictionary
283:List of cutaneous conditions
148:is induced by epidermolytic
2561:Blastomycosis-like pyoderma
2182:Chromobacteriosis infection
2094:Mediterranean spotted fever
172:, which normally holds the
2633:
2581:Tick-borne lymphadenopathy
2383:Gram-negative folliculitis
251:toxic epidermal necrolysis
119:toxic epidermal necrolysis
113:areas. Extensive areas of
1885:Papulonecrotic tuberculid
1870:Mycobacterium haemophilum
961:Streptococcal pharyngitis
527:The Journal of Pediatrics
309:Dermatology: 2-Volume Set
57:
48:
2378:Lymphogranuloma venereum
2084:Flea-borne spotted fever
2057:Rickettsia aeschlimannii
2051:American tick bite fever
1761:Erysipeloid of Rosenbach
1676:Streptococcal intertrigo
1441:Pseudomembranous colitis
1435:Clostridioides difficile
237:is typically indicated.
221:implicated in SSSS have
2509:Trichomycosis axillaris
2046:African tick bite fever
2021:North Asian tick typhus
1941:Cutaneous actinomycosis
1392:Clostridium perfringens
1103:Urinary tract infection
2221:Haemophilus influenzae
2165:Pasteurella hemolytica
2089:Japanese spotted fever
2041:Bacillary angiomatosis
2031:Flying squirrel typhus
2026:Queensland tick typhus
1915:Tuberculous cellulitis
1878:Mycobacterium kansasii
1600:Bacterial skin disease
1498:Ureaplasma urealyticum
1291:Listeria monocytogenes
995:bacitracin resistant,
854:Pneumococcal infection
337:Johns Hopkins Medicine
2536:Elephantiasis nostras
2514:Necrotizing fasciitis
2427:Hospital furunculosis
2109:Brill–Zinsser disease
1740:Dermatitis gangrenosa
1519:Mycoplasma pneumoniae
1512:Mycoplasma genitalium
1351:Clostridium botulinum
1097:Enterococcus faecalis
872:Viridans streptococci
90:Staphylococcus aureus
18:Scalded skin syndrome
2571:Chronic lymphangitis
2240:Hot tub folliculitis
2229:Pseudomonal pyoderma
1856:Miliary tuberculosis
1846:Lichen scrofulosorum
1646:Toxic shock syndrome
1525:Mycoplasma pneumonia
1504:Ureaplasma infection
1214:novobiocin resistant
1172:Toxic shock syndrome
1111:Enterococcus faecium
311:. St. Louis: Mosby.
87:condition caused by
2460:Acute lymphadenitis
2453:Perianal cellulitis
2448:Pyogenic paronychia
2358:Chlamydia infection
2274:Granuloma inguinale
2248:Green nail syndrome
2244:Ecthyma gangrenosum
2119:Cat-scratch disease
1925:Tuberculoid leprosy
1836:Lepromatous leprosy
1683:Streptococcus iniae
1457:(non-spore forming)
1067:Streptococcus bovis
1027:Streptococcus iniae
775:Infectious diseases
381:J. Invest. Dermatol
2607:Bacterial diseases
2504:Pitted keratolysis
2415:Periapical abscess
1826:Erythema induratum
1811:Borderline leprosy
1801:Aquarium granuloma
1365:Clostridium tetani
1248:Bacillus anthracis
865:optochin resistant
780:Bacterial diseases
683:External resources
339:. 19 November 2019
182:pemphigus vulgaris
97:Signs and symptoms
2594:
2593:
2529:Fournier gangrene
2396:
2395:
2295:
2294:
2236:hot-foot syndrome
2209:Vibrio vulnificus
1976:
1975:
1972:
1971:
1920:Tuberculous gumma
1776:
1775:
1566:
1565:
1562:
1561:
1537:Anaeroplasmatales
1474:
1473:
1413:
1412:
1311:
1310:
1307:
1306:
1231:
1230:
1120:
1119:
1076:
1075:
1043:
1042:
922:
921:
731:
730:
451:(9252): 299–301.
318:978-1-4160-2999-1
74:
73:
27:Medical condition
16:(Redirected from
2624:
2566:Bullous impetigo
2487:Sycosis vulgaris
2301:Campylobacterota
2250:
1996:
1987:
1787:
1622:
1613:
1593:
1586:
1579:
1570:
1489:Mycoplasmataceae
1485:
1465:Finegoldia magna
1338:
1322:
1220:S. saprophyticus
1148:
1137:
933:
834:
825:
814:
799:
758:
751:
744:
735:
610:
598:
597:
557:
551:
550:
518:
512:
511:
483:
477:
476:
440:
434:
433:
413:
407:
406:
396:
372:
366:
355:
349:
348:
346:
344:
329:
323:
322:
304:
130:immunosuppressed
53:
43:bullous impetigo
30:
21:
2632:
2631:
2627:
2626:
2625:
2623:
2622:
2621:
2597:
2596:
2595:
2590:
2402:
2392:
2316:
2291:
2227:
2186:
2172:Meningococcemia
2133:
2104:Verruga peruana
2011:Epidemic typhus
1968:
1929:
1831:Histoid leprosy
1792:
1772:
1744:
1719:
1710:Corynebacterium
1703:
1650:
1602:
1597:
1567:
1558:
1531:
1470:
1447:
1409:
1377:
1303:
1274:
1262:Bacillus cereus
1227:
1183:
1128:
1116:
1072:
1039:
1014:
982:
976:Rheumatic fever
918:
860:
805:
803:Lactobacillales
788:
762:
732:
727:
726:
678:
677:
621:
607:
602:
601:
559:
558:
554:
520:
519:
515:
485:
484:
480:
442:
441:
437:
424:(4011): 89–95.
415:
414:
410:
374:
373:
369:
356:
352:
342:
340:
331:
330:
326:
319:
306:
305:
301:
296:
279:
259:
247:
203:
190:
142:
140:Pathophysiology
103:Nikolsky's sign
99:
28:
23:
22:
15:
12:
11:
5:
2630:
2628:
2620:
2619:
2614:
2609:
2599:
2598:
2592:
2591:
2589:
2588:
2586:Tropical ulcer
2583:
2578:
2573:
2568:
2563:
2558:
2553:
2548:
2543:
2538:
2533:
2532:
2531:
2526:
2516:
2511:
2506:
2501:
2496:
2491:
2490:
2489:
2484:
2473:
2472:
2467:
2465:Pilonidal cyst
2462:
2457:
2456:
2455:
2450:
2436:
2431:
2430:
2429:
2419:
2418:
2417:
2406:
2404:
2398:
2397:
2394:
2393:
2391:
2390:
2385:
2380:
2375:
2370:
2368:Rat-bite fever
2365:
2360:
2355:
2350:
2345:
2340:
2335:
2330:
2324:
2322:
2318:
2317:
2315:
2314:
2305:
2303:
2297:
2296:
2293:
2292:
2290:
2289:
2281:
2276:
2271:
2266:
2261:
2256:
2251:
2225:
2217:
2212:
2205:
2200:
2198:Pasteurellosis
2194:
2192:
2188:
2187:
2185:
2184:
2179:
2174:
2169:
2160:
2155:
2141:
2139:
2135:
2134:
2132:
2131:
2126:
2121:
2116:
2111:
2106:
2101:
2096:
2091:
2086:
2081:
2076:
2071:
2066:
2064:Rickettsialpox
2061:
2053:
2048:
2043:
2038:
2033:
2028:
2023:
2018:
2013:
2008:
2006:Endemic typhus
2002:
2000:
1993:
1991:Pseudomonadota
1984:
1978:
1977:
1974:
1973:
1970:
1969:
1967:
1966:
1961:
1953:
1948:
1943:
1937:
1935:
1931:
1930:
1928:
1927:
1922:
1917:
1912:
1907:
1902:
1897:
1892:
1887:
1882:
1874:
1866:
1858:
1853:
1851:Lupus vulgaris
1848:
1843:
1838:
1833:
1828:
1823:
1818:
1813:
1808:
1803:
1797:
1795:
1791:Mycobacterium-
1784:
1782:Actinomycetota
1778:
1777:
1774:
1773:
1771:
1770:
1763:
1758:
1752:
1750:
1746:
1745:
1743:
1742:
1737:
1731:
1729:
1721:
1720:
1715:
1713:
1705:
1704:
1702:
1701:
1696:
1687:
1678:
1673:
1668:
1662:
1660:
1652:
1651:
1649:
1648:
1643:
1638:
1632:
1630:
1627:Staphylococcus
1619:
1610:
1604:
1603:
1598:
1596:
1595:
1588:
1581:
1573:
1564:
1563:
1560:
1559:
1557:
1556:
1555:
1554:
1541:
1539:
1533:
1532:
1530:
1529:
1528:
1527:
1515:
1508:
1507:
1506:
1493:
1491:
1482:
1476:
1475:
1472:
1471:
1469:
1468:
1460:
1458:
1449:
1448:
1446:
1445:
1444:
1443:
1430:
1428:
1420:Clostridioides
1415:
1414:
1411:
1410:
1408:
1407:
1406:
1405:
1400:
1387:
1385:
1379:
1378:
1376:
1375:
1374:
1373:
1361:
1360:
1359:
1346:
1344:
1335:
1319:
1313:
1312:
1309:
1308:
1305:
1304:
1302:
1301:
1300:
1299:
1286:
1284:
1276:
1275:
1273:
1272:
1271:
1270:
1268:Food poisoning
1258:
1257:
1256:
1243:
1241:
1233:
1232:
1229:
1228:
1226:
1225:
1224:
1223:
1211:
1210:
1209:
1206:S. epidermidis
1193:
1191:
1185:
1184:
1182:
1181:
1180:
1179:
1174:
1169:
1156:
1154:
1145:
1142:Staphylococcus
1134:
1122:
1121:
1118:
1117:
1115:
1114:
1107:
1106:
1105:
1088:
1086:
1078:
1077:
1074:
1073:
1071:
1070:
1059:
1053:
1051:
1045:
1044:
1041:
1040:
1038:
1037:
1036:
1035:
1022:
1020:
1016:
1015:
1013:
1012:
1011:
1010:
992:
990:
984:
983:
981:
980:
979:
978:
973:
968:
963:
958:
941:
939:
930:
924:
923:
920:
919:
917:
916:
908:
901:
894:
887:
880:
868:
866:
862:
861:
859:
858:
857:
856:
843:
841:
831:
822:
811:
796:
790:
789:
787:
786:
777:
763:
761:
760:
753:
746:
738:
729:
728:
725:
724:
713:
699:
687:
686:
684:
680:
679:
676:
675:
664:
653:
638:
622:
617:
616:
614:
613:Classification
606:
605:External links
603:
600:
599:
572:(9273): 2059.
552:
513:
478:
435:
408:
367:
350:
324:
317:
298:
297:
295:
292:
291:
290:
285:
278:
275:
267:Dukes' disease
258:
255:
246:
243:
223:penicillinases
202:
199:
189:
186:
141:
138:
134:kidney failure
111:intertriginous
98:
95:
85:dermatological
72:
71:
66:
60:
59:
55:
54:
46:
45:
39:
35:
34:
26:
24:
14:
13:
10:
9:
6:
4:
3:
2:
2629:
2618:
2615:
2613:
2610:
2608:
2605:
2604:
2602:
2587:
2584:
2582:
2579:
2577:
2574:
2572:
2569:
2567:
2564:
2562:
2559:
2557:
2554:
2552:
2549:
2547:
2546:Botryomycosis
2544:
2542:
2539:
2537:
2534:
2530:
2527:
2525:
2522:
2521:
2520:
2517:
2515:
2512:
2510:
2507:
2505:
2502:
2500:
2497:
2495:
2492:
2488:
2485:
2483:
2480:
2479:
2478:
2475:
2474:
2471:
2468:
2466:
2463:
2461:
2458:
2454:
2451:
2449:
2445:
2442:
2441:
2440:
2437:
2435:
2432:
2428:
2425:
2424:
2423:
2422:Boil/furuncle
2420:
2416:
2413:
2412:
2411:
2408:
2407:
2405:
2399:
2389:
2386:
2384:
2381:
2379:
2376:
2374:
2371:
2369:
2366:
2364:
2363:Leptospirosis
2361:
2359:
2356:
2354:
2351:
2349:
2346:
2344:
2341:
2339:
2336:
2334:
2331:
2329:
2326:
2325:
2323:
2319:
2313:
2311:
2307:
2306:
2304:
2302:
2298:
2288:
2286:
2282:
2280:
2277:
2275:
2272:
2270:
2267:
2265:
2262:
2260:
2259:Salmonellosis
2257:
2255:
2252:
2249:
2245:
2241:
2237:
2235:
2230:
2226:
2224:
2222:
2218:
2216:
2215:Rhinoscleroma
2213:
2211:
2210:
2206:
2204:
2201:
2199:
2196:
2195:
2193:
2189:
2183:
2180:
2178:
2175:
2173:
2170:
2168:
2166:
2161:
2159:
2156:
2154:
2150:
2146:
2143:
2142:
2140:
2136:
2130:
2127:
2125:
2122:
2120:
2117:
2115:
2112:
2110:
2107:
2105:
2102:
2100:
2097:
2095:
2092:
2090:
2087:
2085:
2082:
2080:
2077:
2075:
2072:
2070:
2067:
2065:
2062:
2060:
2058:
2054:
2052:
2049:
2047:
2044:
2042:
2039:
2037:
2034:
2032:
2029:
2027:
2024:
2022:
2019:
2017:
2014:
2012:
2009:
2007:
2004:
2003:
2001:
1997:
1994:
1992:
1988:
1985:
1983:
1979:
1965:
1962:
1960:
1958:
1954:
1952:
1949:
1947:
1944:
1942:
1939:
1938:
1936:
1932:
1926:
1923:
1921:
1918:
1916:
1913:
1911:
1908:
1906:
1903:
1901:
1900:Scrofuloderma
1898:
1896:
1893:
1891:
1888:
1886:
1883:
1881:
1879:
1875:
1873:
1871:
1867:
1865:
1863:
1859:
1857:
1854:
1852:
1849:
1847:
1844:
1842:
1839:
1837:
1834:
1832:
1829:
1827:
1824:
1822:
1819:
1817:
1814:
1812:
1809:
1807:
1804:
1802:
1799:
1798:
1796:
1794:
1788:
1785:
1783:
1779:
1769:
1768:
1764:
1762:
1759:
1757:
1754:
1753:
1751:
1747:
1741:
1738:
1736:
1733:
1732:
1730:
1728:
1727:
1722:
1718:
1714:
1712:
1711:
1706:
1700:
1699:Scarlet fever
1697:
1695:
1691:
1688:
1686:
1684:
1679:
1677:
1674:
1672:
1669:
1667:
1664:
1663:
1661:
1659:
1658:
1657:Streptococcus
1653:
1647:
1644:
1642:
1639:
1637:
1634:
1633:
1631:
1629:
1628:
1623:
1620:
1618:
1614:
1611:
1609:
1605:
1601:
1594:
1589:
1587:
1582:
1580:
1575:
1574:
1571:
1553:
1550:
1549:
1548:
1547:
1543:
1542:
1540:
1538:
1534:
1526:
1523:
1522:
1521:
1520:
1516:
1514:
1513:
1509:
1505:
1502:
1501:
1500:
1499:
1495:
1494:
1492:
1490:
1486:
1483:
1481:
1477:
1467:
1466:
1462:
1461:
1459:
1456:
1455:
1450:
1442:
1439:
1438:
1437:
1436:
1432:
1431:
1429:
1426:
1422:
1421:
1416:
1404:
1401:
1399:
1396:
1395:
1394:
1393:
1389:
1388:
1386:
1384:
1380:
1372:
1369:
1368:
1367:
1366:
1362:
1358:
1355:
1354:
1353:
1352:
1348:
1347:
1345:
1343:
1339:
1336:
1333:
1329:
1328:
1323:
1320:
1318:
1314:
1298:
1295:
1294:
1293:
1292:
1288:
1287:
1285:
1283:
1282:
1277:
1269:
1266:
1265:
1264:
1263:
1259:
1255:
1252:
1251:
1250:
1249:
1245:
1244:
1242:
1240:
1239:
1234:
1222:
1221:
1217:
1216:
1215:
1212:
1208:
1207:
1203:
1202:
1201:
1199:
1195:
1194:
1192:
1190:
1186:
1178:
1175:
1173:
1170:
1168:
1165:
1164:
1163:
1162:
1158:
1157:
1155:
1153:
1149:
1146:
1144:
1143:
1138:
1135:
1132:
1127:
1123:
1113:
1112:
1108:
1104:
1101:
1100:
1099:
1098:
1093:
1090:
1089:
1087:
1085:
1084:
1079:
1069:
1068:
1063:
1060:
1058:
1055:
1054:
1052:
1050:
1046:
1034:
1031:
1030:
1029:
1028:
1024:
1023:
1021:
1017:
1009:
1006:
1005:
1004:
1003:
1002:S. agalactiae
998:
994:
993:
991:
989:
985:
977:
974:
972:
969:
967:
966:Scarlet fever
964:
962:
959:
957:
954:
953:
952:
951:
947:susceptible:
946:
943:
942:
940:
938:
934:
931:
929:
925:
915:
913:
909:
907:
906:
902:
900:
899:
895:
893:
892:
888:
886:
885:
881:
879:
878:
873:
870:
869:
867:
863:
855:
852:
851:
850:
849:
848:S. pneumoniae
845:
844:
842:
839:
835:
832:
830:
826:
823:
821:
820:
819:Streptococcus
815:
812:
809:
804:
800:
797:
795:
791:
785:
781:
778:
776:
772:
768:
765:
764:
759:
754:
752:
747:
745:
740:
739:
736:
723:
719:
718:
714:
712:
709:
705:
704:
700:
698:
694:
693:
689:
688:
685:
681:
674:
670:
669:
665:
663:
659:
658:
654:
652:
648:
647:
643:
639:
637:
633:
632:
628:
624:
623:
620:
615:
611:
604:
595:
591:
587:
583:
579:
575:
571:
567:
563:
556:
553:
548:
544:
540:
536:
533:(6): 958–67.
532:
528:
524:
517:
514:
509:
505:
501:
497:
493:
489:
482:
479:
474:
470:
466:
462:
458:
454:
450:
446:
439:
436:
431:
427:
423:
419:
412:
409:
404:
400:
395:
390:
386:
382:
378:
371:
368:
365:
364:
359:
354:
351:
338:
334:
328:
325:
320:
314:
310:
303:
300:
293:
289:
286:
284:
281:
280:
276:
274:
272:
271:scarlet fever
268:
262:
256:
254:
252:
244:
242:
240:
236:
232:
228:
224:
220:
216:
212:
208:
200:
198:
195:
187:
185:
183:
179:
175:
171:
167:
163:
159:
155:
151:
147:
139:
137:
135:
131:
126:
122:
120:
116:
112:
108:
104:
96:
94:
92:
91:
86:
82:
78:
70:
67:
65:
61:
56:
52:
47:
44:
40:
36:
31:
19:
2551:Malakoplakia
2477:Folliculitis
2401:Unspecified
2373:Lyme disease
2310:Helicobacter
2309:
2284:
2233:
2220:
2207:
2164:
2145:Gonococcemia
2056:
2036:Trench fever
2016:Scrub typhus
1956:
1877:
1869:
1861:
1821:Buruli ulcer
1790:
1765:
1735:Gas gangrene
1724:
1708:
1682:
1655:
1635:
1625:
1544:
1517:
1510:
1496:
1463:
1452:
1433:
1418:
1398:Gas gangrene
1390:
1382:
1363:
1349:
1341:
1325:
1289:
1279:
1260:
1246:
1236:
1218:
1213:
1204:
1196:
1166:
1159:
1140:
1109:
1095:
1083:Enterococcus
1081:
1065:
1025:
1000:
948:
912:S. anginosus
911:
903:
898:S. sanguinis
896:
889:
882:
875:
846:
817:
715:
701:
690:
666:
655:
640:
625:
569:
565:
555:
530:
526:
516:
494:(1): 88–91.
491:
487:
481:
448:
444:
438:
421:
417:
411:
387:(4): 700–3.
384:
380:
370:
361:
358:"exfoliatin"
353:
341:. Retrieved
336:
327:
308:
302:
263:
260:
248:
218:
214:
204:
193:
191:
170:desmoglein-1
157:
143:
127:
123:
115:desquamation
107:erythroderma
100:
88:
80:
76:
75:
2556:Pyomyositis
2264:Shigellosis
2234:Pseudomonas
2158:Melioidosis
2124:Oroya fever
2114:Brucellosis
1946:Nocardiosis
1756:Listeriosis
1726:Clostridium
1552:Erysipeloid
1327:Clostridium
1297:Listeriosis
1200:susceptible
950:S. pyogenes
905:S. sobrinus
840:susceptible
692:MedlinePlus
239:Clindamycin
211:paracetamol
69:Dermatology
38:Other names
2601:Categories
2444:Paronychia
2439:Cellulitis
2312:cellulitis
2223:cellulitis
2163:Cutaneous
1767:Mycoplasma
1717:Erythrasma
1690:Erysipelas
1681:Cutaneous
1480:Mollicutes
1454:Finegoldia
1383:nonmotile:
1317:Clostridia
1198:novobiocin
1126:Bacillales
971:Erysipelas
945:bacitracin
668:DiseasesDB
566:The Lancet
445:The Lancet
418:The Lancet
294:References
235:vancomycin
174:granulosum
162:desmosomes
154:exfoliatin
2434:Carbuncle
2287:infection
2285:Aeromonas
2279:Chancroid
2203:Tularemia
2167:infection
2149:Gonorrhea
2059:infection
1959:infection
1880:infection
1872:infection
1864:infection
1685:infection
1617:Bacillota
1427:-forming)
1334:-forming)
1161:S. aureus
1019:ungrouped
997:CAMP test
891:S. oralis
884:S. mutans
767:Bacillota
711:emerg/782
703:eMedicine
245:Prognosis
231:oxacillin
227:nafcillin
219:S. aureus
215:S. aureus
207:ibuprofen
201:Treatment
194:S. aureus
188:Diagnosis
158:S. aureus
150:exotoxins
64:Specialty
2519:Gangrene
2470:Pyoderma
2403:pathogen
2333:Syphilis
2328:Syphilid
2177:Glanders
1982:Gram -ve
1666:Impetigo
1641:Impetigo
1608:Gram +ve
1357:Botulism
1281:Listeria
1238:Bacillus
877:S. mitis
838:optochin
717:Orphanet
708:derm/402
594:35925579
586:11441870
473:35896288
465:11214144
403:15816826
277:See also
178:spinosum
146:syndrome
132:or have
2499:Ecthyma
2410:Abscess
2338:Chancre
2254:Q fever
1841:Leprosy
1793:related
1371:Tetanus
1342:motile:
1254:Anthrax
794:Bacilli
662:D013206
547:4252715
343:1 March
257:History
166:plasmid
83:) is a
2494:Pimple
2269:Plague
1934:Others
1749:Others
697:001352
651:695.81
592:
584:
545:
508:367152
506:
471:
463:
401:
315:
2353:Bejel
2348:Pinta
2321:Other
2191:Gamma
1999:Alpha
1425:spore
1332:spore
914:group
769:(low-
722:36236
673:29437
590:S2CID
469:S2CID
233:, or
2343:Yaws
2138:Beta
1177:MRSA
1131:Cat+
808:Cat-
657:MeSH
646:9-CM
582:PMID
543:PMID
504:PMID
461:PMID
399:PMID
345:2023
313:ISBN
176:and
144:The
81:SSSS
1189:Cg-
1152:Cg+
1094:+:
1092:BEA
1064:+:
1062:BEA
999:+:
771:G+C
642:ICD
636:L00
627:ICD
574:doi
570:357
535:doi
496:doi
492:133
453:doi
449:357
426:doi
422:156
389:doi
385:124
360:at
209:or
2603::
2446:/
2246:/
2242:/
2238:/
2231:/
1692:/
874::
784:G+
782::
773:)
720::
706::
695::
671::
660::
649::
634::
631:10
588:.
580:.
568:.
564:.
541:.
531:78
529:.
525:.
502:.
490:.
467:.
459:.
447:.
420:.
397:.
383:.
379:.
335:.
229:,
184:.
136:.
93:.
2151:/
2147:/
1592:e
1585:t
1578:v
1423:(
1330:(
1133:)
1129:(
1057:D
1049:Îł
988:B
937:A
928:β
829:α
810:)
806:(
757:e
750:t
743:v
644:-
629:-
619:D
596:.
576::
549:.
537::
510:.
498::
475:.
455::
432:.
428::
405:.
391::
347:.
321:.
152:(
79:(
20:)
Text is available under the Creative Commons Attribution-ShareAlike License. Additional terms may apply.