304:. Behavioral inhibitions, or inhibited temperaments, encompass feelings of emotional distress and social withdrawals. In a 2016 study, the relationship between behavioral inhibition and selective mutism was investigated. Children between the ages of three and 19 with lifetime selective mutism, social phobia, internalizing behavior, and healthy controls were assessed using the parent-rated Retrospective Infant Behavioral Inhibition (RIBI) questionnaire, consisting of 20 questions that addressed shyness and fear, as well as other subscales. The results indicated behavioral inhibition does indeed predispose selective mutism. Corresponding with the researchers’ hypothesis, children diagnosed with long-term selective mutism had a higher behavioral inhibition score as an infant. This is indicative of the positive correlation between behavioral inhibition and selective mutism.
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their anxiety levels in situations where speech is expected. Due to these problems, a change of environment may be a viable consideration. However, changing school is worth considering only if the alternative environment is highly supportive, otherwise a whole new environment could also be a social shock for the individual or deprive them of any friends or support they have currently. Regardless of the cause, increasing awareness and ensuring an accommodating, supportive environment are the first steps towards effective treatment. Most often affected children do not have to change schools or classes and have no difficulty keeping up except on the communication and social front. Treatment in teenage or adult years can be more difficult because the affected individual has become accustomed to being mute, and lacks social skills to respond to social cues.
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oppositional aspect of the disorder. Instead, it highlighted that in select environments, the child is unable to speak rather than choosing not to. In fact, children with selective mutism have a lower rate of oppositional behavior than their peers in a school setting. Some previous studies on the subject of selective mutism have been dismissed as containing serious flaws in their design. According to a more recent systematic study it is believed that children or adults who have selective mutism are not more likely than other children or adults to have a history of early trauma or stressful life events. Many children or adults who have selective mutism almost always speak confidently in some situations.
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completely silent at school for years but speak quite freely or even excessively at home. There is a hierarchical variation among people with this disorder: some people participate fully in activities and appear social but do not speak, others will speak only to peers but not to adults, others will speak to adults when asked questions requiring short answers but never to peers, and still others speak to no one and participate in few, if any, activities presented to them. In a severe form known as "progressive mutism", the disorder progresses until the person with this condition no longer speaks to anyone in any situation, even close family members.
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definitive answers yet due to the under-diagnosis and small/biased sample sizes. Many people are not diagnosed until late in childhood only because they do not speak at school and therefore fail to accomplish assignments requiring public speaking. Their involuntary silence makes the condition harder to understand or test. Parents often are unaware of the condition since the children may be functioning well at home. Teachers and pediatricians also sometimes mistake it for severe shyness or common stage fright.
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prompter and asks the child the same questions, this time eliciting a verbal response. The two videos of the conversations are then edited together to show the child directly answering the questions posed by the teacher or other adult. This video is then shown to the child over a series of several weeks, and every time the child sees themself verbally answering the teacher/other adult, the tape is stopped and the child is given positive reinforcement.
362:(CBT), and an insight-oriented approach to increase social communication and promote social confidence. Tactics such as systemic desensitization, modeling, fading, and positive reinforcement enable individuals to develop social engagement skills and begin to progress communicatively in a step-by-step manner. There are many treatment plans that exist and it is recommended for families to do thorough research before deciding on their treatment approach.
202:, repetitive behaviors, social isolation even among family members (not always answering to name, for example)—that set them apart from a child with selective mutism alone. Some autistic people may be selectively mute due to anxiety in unfamiliar social situations. If mutism is entirely due to autism spectrum disorder, it cannot be diagnosed as selective mutism as stated in the last item on the list above.
355:, public school districts are required to provide a free, appropriate public education to every "qualified handicapped person" residing within their jurisdiction. If the child is found to have impairments that substantially limit a major life activity (in this case, learning), the education agency has to decide what related aids or services are required to provide equal access to the learning environment.
468:. By parent report, fluoxetine-treated children showed significantly greater improvement than placebo-treated children. In another, Dummit III et al. (1996) administered fluoxetine to 21 children for nine weeks and found that 76% of the children had reduced or no symptoms by the end of the experiment. This indicates that fluoxetine is an SSRI that is indeed helpful in treating selective mutism.
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501:(DSM), first published in 1952, first included selective mutism in its third edition, published in 1980. Selective mutism was described as "a continuous refusal to speak in almost all social situations" despite normal ability to speak. While "excessive shyness" and other anxiety-related traits were listed as associated features, predisposing factors included "maternal
191:. In fact, the majority of children diagnosed with selective mutism also have social anxiety disorder (100% of participants in two studies and 97% in another). Some researchers therefore speculate that selective mutism may be an avoidance strategy used by a subgroup of children with social anxiety disorder to reduce their distress in social situations.
312:. This could cause anxiety and a sense of being overwhelmed in unfamiliar situations, which may cause the child or adult to "shut down" and not be able to speak (something that some autistic people also experience). Many children or adults with selective mutism have some auditory processing difficulties.
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Medication, when used, should never be considered the entire treatment for a person with selective mutism. However, the reason why medication needs to be considered as a treatment at all is because selective mutism is still prevalent, despite psychosocial efforts. But while on medication, the person
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Mystery motivation is often paired with self-modeling. An envelope is placed in the child's classroom in a visible place. On the envelope, the child's name is written along with a question mark. Inside is an item that the child's parent has determined to be desirable to the child. The child is told
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An affected child is brought into the classroom or the environment where the child will not speak and is videotaped. First, the teacher or another adult prompts the child with questions that likely will not be answered. A parent, or someone the child feels comfortable speaking to, then replaces the
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Consequently, treatment at an early age is important. If not addressed, selective mutism tends to be self-reinforcing. Others may eventually expect an affected child to not speak and therefore stop attempting to initiate verbal contact. Alternatively, they may pressure the child to talk, increasing
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identified what she called four "subtypes" of elective mutism (as it was called then), although this set of subtypes is not in current diagnostic use. These subtypes are no longer recognized, though "speech phobia" is sometimes used to describe a selectively mute person who appears not to have any
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As an example, a child may be playing a board game with a family member in a classroom at school. Gradually, the teacher is brought in to play as well. When the child adjusts to the teacher's presence, then a peer is brought in to be a part of the game. Each person is only brought in if the child
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The exact treatment depends on the person's age, any comorbid mental illnesses, and a number of other factors. For instance, stimulus fading is typically used with younger children because older children and teenagers recognize the situation as an attempt to make them speak, and older people with
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About 20–30% of children or adults with selective mutism have speech or language disorders that add stress to situations in which the child is expected to speak. In the DSM-4, the term “elective mutism” was changed to “selective mutism.” This name change intended to deemphasize this refusal and
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Selective mutism (SM) is an umbrella term for the condition of otherwise well-developed children or adults who cannot speak or communicate under certain settings. The exact causes that affect each person may be different and yet unknown. There have been attempts to categorize, but there are no
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Contrary to popular belief, people with selective mutism do not necessarily improve with age. Effective treatment is necessary for a child to develop properly. Without treatment, selective mutism can contribute to chronic depression, further anxiety, and other social and emotional problems.
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Children and adults with selective mutism are fully capable of speech and understanding language but are completely unable to speak in certain situations, though speech is expected of them. The behaviour may be perceived as shyness or rudeness by others. A child with selective mutism may be
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to be helpful in treating children and adults with selective mutism, to decrease anxiety levels and thereby speed the process of therapy. Use of medication may end after nine to twelve months, once the person has learned skills to cope with anxiety and has become more comfortable in social
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indicates a widespread misconception among psychologists that selectively mute people choose to be silent in certain situations, while the truth is that they often wish to speak but are unable to do so. To reflect the involuntary nature of this disorder, the name was changed to
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Spacing is important to integrate, especially with self-modeling. Repeated and spaced out use of interventions is shown to be the most helpful long-term for learning. Viewing videotapes of self-modeling should be shown over a spaced out period of time of approximately 6 weeks.
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Such videos can also be shown to affected children's classmates to set an expectation in their peers that they can speak. The classmates thereby learn the sound of the child's voice and, albeit through editing, have the opportunity to see the child conversing with the teacher.
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that when they ask for the envelope loudly enough for the teacher and others in the classroom to hear, the child will receive the mystery motivator. The class is also told of the expectation that the child ask for the envelope loudly enough that the class can hear.
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of selective mutism is not certain. Due to the poor understanding of this condition by the general public, many cases are likely undiagnosed. Based on the number of reported cases, the figure is commonly estimated to be 1 in 1000, 0.1%. However, a 2002 study in
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Since selective mutism is categorized as an anxiety disorder, using similar medication to treat either makes sense. Antidepressants have been used in addition to self-modeling and mystery motivation to aid in the learning process. Furthermore,
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344:(IDEA), a federal law, those with the disorder qualify for services based upon the fact that they have an impairment that hinders their ability to speak, thus disrupting their lives. This assistance is typically documented in the form of an
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Given the very high incidence of social anxiety disorder within selective mutism (as high as 100% in some studies), it is possible that social anxiety disorder causes selective mutism. Some children or adults with selective mutism may have
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However, there are some positive features of selective mutism. These include above average intelligence, inquisitiveness, or perception; a strong sense of right and wrong; creativity; love for the arts; empathy; and sensitivity for other
464:, ten studies were looked at which involved SSRI medications, and all reported medication was well tolerated. In one of them, Black and Uhde (1994) conducted a double-blind, placebo-controlled study investigating the effects of
198:, especially if the child acts particularly withdrawn around their diagnostician, which can lead to incorrect diagnosis and treatment. Although many autistic people are also selectively mute, they often display other behaviors—
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in 1994, although some people are calling for a name change to "situational mutism" because the current name can promote the belief that it is a behavior the individual selects rather than it occurring in certain situations.
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Affected subjects can be brought into a controlled environment with someone with whom they are at ease and can communicate. Gradually, another person is introduced into the situation. One example of stimulus fading is the
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Gensthaler, Angelika; Khalaf, Sally; Ligges, Marc; Kaess, Michael; Freitag, Christine M.; Schwenck, Chrstina (October 2016). "Selective mutism and temperament: the silence and behavioral inhibition to the unfamiliar".
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technique, where a new person is slowly brought into the talking group. This can take a long time for the first one or two faded-in people but may become faster as the patient gets more comfortable with the technique.
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In 1994, Sue Newman, co-founder of the
Selective Mutism Foundation, requested that the fourth edition of the DSM reflect the name change from elective mutism to selective mutism and describe the disorder as a
414:, voice or video recordings, and speaking or whispering to an intermediary in the presence of the target person. This can make the subject more comfortable with the idea of communicating with this person.
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Klein, Evelyn R.; Armstrong, Sharon Lee; Skira, Kathryn; Gordon, Janice (January 2017). "Social
Communication Anxiety Treatment (S-CAT) for children and families with selective mutism: A pilot study".
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first for interacting nonverbally, then for saying certain sounds (such as the sound that each letter of the alphabet makes) rather than words, then for whispering, and finally saying a word or more.
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Social
Communication Anxiety Treatment (S-CAT) is a common treatment approach by professionals and has proven to be successful. S-CAT integrates components of behavioral-therapy,
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Kehle, Thomas J.; Madaus, Melissa R.; Baratta, Victoria S.; Bray, Melissa A. (September 1998). "Augmented Self-Modeling as a
Treatment for Children with Selective Mutism".
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Chvira, Denise A.; Shipon-Blum, Elisa; Hitchcock, Carla; Cohan, Sharon; Stein, Murray B. (2007). "Selective Mutism and Social
Anxiety Disorder: All in the Family?".
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American
Psychiatric Association (2013). Diagnostic and Statistical Manual of Mental Disorders (Fifth ed.). Arlington, VA: American Psychiatric Publishing. p. 195.
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should still be in therapy to help them learn how to handle anxiety and prepare them for life without medication, as medication is typically a short-term solution.
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Sharp, William G.; Sherman, Colleen; Gross, Alan M. (1 January 2007). "Selective mutism and anxiety: A review of the current conceptualization of the disorder".
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Consistent failure to speak in specific social situations (in which there is an expectation for speaking, e.g., at school) despite speaking in other situations.
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Besides lack of speech, other common behaviors and characteristics displayed by selectively mute people, according to Elisa Shipon-Blum's findings, include:
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The subject communicates indirectly with a person to whom they are afraid to speak through such means as email, instant messaging (text, audio or video),
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moved selective mutism from the section "Disorders
Usually First Diagnosed in Infancy, Childhood, or Adolescence" to the section for anxiety disorders.
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1958:
513:. Elective mutism in the third edition revised (DSM III-R) is described similarly to the third edition except for specifying that the disorder is
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Shriver, Mark D.; Segool, Natasha; Gortmaker, Valerie (2011). "Behavior
Observations for Linking Assessment to Treatment for Selective Mutism".
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Manassis, Katharina; Oerbeck, Beate; Overgaard, Kristen Romvig (June 2016). "The use of medication in selective mutism: A systematic review".
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Like other disabilities, adequate accommodations are needed for those with the condition to succeed at school, work, and in the home. In the
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situations. Medication is more often used for older children, teenagers, and adults whose anxiety has led to depression and other problems.
832:
Sharp, W. G.; Sherman, C.; Gross, A. M. (2007). "Selective mutism and anxiety: A review of the current conceptualization of the disorder".
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Most children and adults with selective mutism are hypothesized to have an inherited predisposition to anxiety. They often have inhibited
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becomes unable to speak when exposed to specific situations, specific places, or to specific people, one or multiple of which serving as
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81:. People with selective mutism stay silent even when the consequences of their silence include shame, social ostracism, or punishment.
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Cohan, Sharon L.; Chavira, Denise A.; Shipon-Blum, Elisa; Hitchcock, Carla; Roesch, Scott C.; Stein, Murray B. (7 October 2008).
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Vecchio, J. L.; Kearney, C. A. (2005). "Selective Mutism in
Children: Comparison to Youths with and Without Anxiety Disorders".
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Bergman, RL; Piacentini, J; McCracken, JT (2002). "Prevalence and description of selective mutism in a school-based sample".
484:. Although this is now an obsolete term, it was part of an early effort to describe the concept now called selective mutism.
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Dummit, E. Steven; Klein, Rachel G.; Tancer, Nancy K.; Asche, Barbara; Martin, Jacqueline; Fairbanks, Janet A. (May 1997).
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Viana, A. G.; Beidel, D. C.; Rabian, B. (2009). "Selective mutism: A review and integration of the last 15 years".
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Black, B.; Uhde, T. W. (1995). "Psychiatric
Characteristics of Children with Selective Mutism: A Pilot Study".
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The failure to speak is not due to a lack of knowledge of the spoken language required in the social situation.
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Anstendig, Karin (1998). "Selective mutism: A review of the treatment literature by modality from 1980–1996".
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described children who were able to speak normally but often refused to as having a disorder he named
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Dummit, E Steven; Klein, Rachel G.; Asche, Barbara; Martin, Jacqueline; Tancer, Nancy K. (May 1996).
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The disturbance interferes with educational or occupational achievement or with social communication.
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Steinhausen, Hans-Christoph; Juzi, Claudia (May 1996). "Elective Mutism: An Analysis of 100 Cases".
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to speak. The relation to anxiety disorders was emphasized, particularly in the revised version (
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Many are above average in intelligence, creative, and sensitive to others thoughts and feelings.
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The duration of the disturbance is at least 1 month (not limited to the first month of school).
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Perednik, Ruth (1 June 2012). "An interview with Ruth Perednik: treating selective mutism".
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Shyness, social anxiety, fear of social embarrassment or social isolation and withdrawal
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Particularly in young children, selective mutism can sometimes be conflated with an
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Selective mutism is strongly associated with other anxiety disorders, particularly
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this condition and people with depression are more likely to need medication.
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To meet DSM-5 criteria for selective mutism, one must exhibit the following:
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McHolm, Angela E., Cunningham, Charles E., & Vanier, Melanie K. (2005).
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1755:(Fifth ed.). Arlington, VA: American Psychiatric Publishing. pp.
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Anxiety disorder causing the inability to speak under certain circumstances
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On the flip side, there are some positive traits observed in many cases:
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1672:"Fluoxetine Treatment of Children with Selective Mutism: An Open Trial"
119: in this section. Unsourced material may be challenged and removed.
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300:. This area receives indications of possible threats and sets off the
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The Journal of the American Academy of Child and Adolescent Psychiatry
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Journal of the American Academy of Child & Adolescent Psychiatry
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Journal of the American Academy of Child & Adolescent Psychiatry
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Journal of the American Academy of Child & Adolescent Psychiatry
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Journal of the American Academy of Child & Adolescent Psychiatry
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Journal of the American Academy of Child & Adolescent Psychiatry
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Selective Mutism Anxiety & Related Disorders Treatment Center
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1713:"Selective mutism what is selective mutism childhood disorder"
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Some practitioners believe there would be evidence indicating
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1208:"Selective Mutism: What it is and Approaches to Intervention"
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in particular have been used to treat selective mutism. In a
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Blank expression and reluctance to smile or incessant smiling
668:"Systematic Assessment of 50 Children With Selective Mutism"
529:). As part of the reorganization of the DSM categories, the
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Moini, Jahangir; Justin Koenitzer; Anthony LoGalbo (2021).
1356:"What about adults? What are the long-term effects of SM?"
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The subject is slowly encouraged to speak. The subject is
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Above average intelligence, inquisitiveness, or perception
1418:"Your Rights Under Section 504 of the Rehabilitation Act"
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Tendency to worry more than most people of the same age
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When do I need to seek professional help for my child?
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Difficulty expressing feelings, even to family members
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Diagnostic and Statistical Manual of Mental Disorders
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Journal of Clinical Child & Adolescent Psychology
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Diagnostic and Statistical Manual of Mental Disorders
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Journal of Psychopathology and Behavioral Assessment
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Psychotherapy: Theory, Research, Practice, Training
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783:Yeganeh, R.; Beidel, D. C.; Turner, S. M. (2006).
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167:The disturbance is not better accounted for by a
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175:) and does not occur exclusively in people with
1788:. Oakland, Calif.: New Harbinger Publications.
1401:"The Older Child or Teen with Selective Mutism"
1335:Selective Mutism Group: Ask the Doc archives:
65:in which a person who is otherwise capable of
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785:"Selective mutism: More than social anxiety?"
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402:continues to engage verbally and positively.
353:Section 504 of the Rehabilitation Act of 1973
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342:Individuals with Disabilities Education Act
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1629:European Child & Adolescent Psychiatry
1311:Johnson, Maggie; Wintgens, Alison (2001).
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1117:European Child & Adolescent Psychiatry
1026:. London: Academic Press. pp. 82–84.
77:. Selective mutism usually co-exists with
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1749:American Psychiatric Association (2013).
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972:. Theselectivemutism.info. Archived from
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135:Learn how and when to remove this message
1786:Helping Your Child with Selective Mutism
1443:Clinical Child Psychology and Psychiatry
998:. Myoutofcontrolteen.com. Archived from
2083:Mental disorders diagnosed in childhood
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1382:"Killer's history of social disorders"
600:"The Child Who Would Not Speak a Word"
310:trouble processing sensory information
229:estimated the incidence to be 0.71%.
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1313:The Selective Mutism Resource Manual
1061:North American Journal of Psychology
1023:Global Emergency of Mental Disorders
994:Online Parent Support (2005-05-26).
117:adding citations to reliable sources
1531:Education and Treatment of Children
1943:Emotional and behavioral disorders
928:J Am Acad Child Adolesc Psychiatry
244:Difficulty maintaining eye contact
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1738:Classification of Elective Mutism
267:A strong sense of right and wrong
1689:10.1097/00004583-199605000-00016
1287:10.1097/00004583-199605000-00015
940:10.1097/00004583-200208000-00012
878:"Situational / Selective Mutism"
762:10.1097/00004583-199507000-00007
685:10.1097/00004583-199705000-00016
598:Brown, Harriet (12 April 2005).
346:Individualized Education Program
173:childhood-onset fluency disorder
93:
1614:"Treatment Of Selective Mutism"
1380:Ketteley, Emma (8 April 2008).
256:Sensitivity to noise and crowds
179:or psychotic disorders such as
104:needs additional citations for
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2040:Stereotypic movement disorder
1974:Emotional/behavioral disorder
1969:Oppositional defiant disorder
1507:10.1016/S0022-4405(98)00013-2
1252:10.1016/j.janxdis.2006.07.002
856:10.1016/j.janxdis.2006.07.002
351:Under another law in the US,
1495:Journal of School Psychology
1230:Journal of Anxiety Disorders
905:10.1097/chi.0b013e318149366a
834:Journal of Anxiety Disorders
492:symptoms of social anxiety.
360:cognitive-behavioral therapy
279:Sensitivity for other people
1597:"WHAT is Selective Mutism?"
970:"Selective Mutism Symptoms"
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1097:"What Is Selective Mutism"
565:Clinical Psychology Review
517:related to social phobia.
476:In 1877, German physician
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1176:10.1080/15374410802359759
1129:10.1007/s00787-016-0835-4
724:10.1007/s10862-005-3263-1
577:10.1016/j.cpr.2008.09.009
543:June and Jennifer Gibbons
177:autism spectrum disorders
1455:10.1177/1359104516633497
302:fight-or-flight response
196:autism spectrum disorder
73:. This is caused by the
625:. LangMarc Publishing.
189:social anxiety disorder
79:social anxiety disorder
789:Depression and Anxiety
169:communication disorder
2045:Elimination disorders
1543:10.1353/etc.2011.0023
1951:Emotional/behavioral
617:Adelman, L. (2007).
487:In 1980, a study by
113:improve this article
1985:Social functioning
1980:Separation anxiety
1886:External resources
1342:2012-03-11 at the
996:"Selective Mutism"
604:The New York Times
545:, the Silent Twins
507:mental retardation
482:aphasia voluntaria
379:Mystery motivators
85:Signs and symptoms
2078:Anxiety disorders
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2014:Tourette syndrome
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1322:978-0-86388-280-7
1033:978-0-323-85843-4
651:978-0-89042-555-8
621:Don't Call me Shy
462:systematic review
273:Love for the arts
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16:(Redirected from
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214:selective mutism
205:The former name
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63:anxiety disorder
55:Selective mutism
36:Selective mutism
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1736:Torey Hayden.
1729:
1711:Tots, Bright.
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1682:(5): 615–621.
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1501:(3): 247–260.
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1386:BBC This World
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1315:. Speechmark.
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1281:(5): 606–614.
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1236:(4): 568–579.
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1199:
1170:(4): 770–784.
1150:
1106:
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1032:
1012:
986:
961:
918:
883:
869:
840:(4): 568–579.
824:
795:(3): 117–123.
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678:(5): 653–660.
655:
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632:978-1880292327
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1719:on 2007-12-14
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1449:(1): 90–108.
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1399:Blau, Ricki.
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1721:. Retrieved
1717:the original
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1635:(6): 571–8.
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571:(1): 57–67.
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489:Torey Hayden
486:
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340:, under the
335:
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314:
306:
294:temperaments
291:
287:
259:
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206:
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150:
146:
131:
122:
111:Please help
106:verification
103:
58:
54:
53:
1423:. June 2006
445:anxiolytics
412:online chat
125:August 2010
2072:Categories
2055:Encopresis
2033:Cluttering
2028:Stuttering
1723:2009-07-14
1427:2023-02-09
1366:2008-05-09
1214:2023-02-14
1210:. May 2019
1080:1013609961
1073:A288873877
1067:(2): 365.
1042:1252050397
1006:2013-02-21
980:2013-02-21
466:fluoxetine
424:reinforced
395:sliding-in
270:Creativity
47:Psychiatry
1895:eMedicine
1871:SNOMED CT
1551:143555332
1471:206708229
1238:CiteSeerX
842:CiteSeerX
732:144770110
718:: 31–37.
550:Citations
527:DSM IV-TR
320:Treatment
222:incidence
42:Specialty
2088:Muteness
2050:Enuresis
1900:ped/2660
1876:71959007
1802:60414597
1649:26560144
1463:26940121
1340:Archived
1260:16949249
1194:18991128
1145:12074063
1137:26970743
1076:ProQuest
956:20947226
948:12162629
913:18049296
864:16949249
819:39403140
811:16421889
585:18986742
537:See also
298:amygdala
200:stimming
71:triggers
61:) is an
1865:D009155
1698:8935208
1657:5859770
1295:8935207
1185:2925839
1047:people.
770:7649954
694:9136500
523:failure
509:", and
472:History
430:Spacing
418:Shaping
276:Empathy
171:(e.g.,
1854:313.23
1851:309.83
1800:
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511:trauma
284:Causes
67:speech
1976:(EBD)
1836:F94.0
1653:S2CID
1600:(PDF)
1547:S2CID
1467:S2CID
1421:(PDF)
1404:(PDF)
1141:S2CID
952:S2CID
815:S2CID
728:S2CID
531:DSM-5
458:SSRIs
1959:ADHD
1860:MeSH
1846:9-CM
1798:OCLC
1790:ISBN
1761:ISBN
1694:PMID
1645:PMID
1459:PMID
1317:ISBN
1291:PMID
1256:PMID
1190:PMID
1133:PMID
1069:Gale
1038:OCLC
1028:ISBN
944:PMID
909:PMID
860:PMID
807:PMID
766:PMID
690:PMID
647:ISBN
627:ISBN
581:PMID
505:", "
495:The
220:The
2000:DAD
1995:RAD
1842:ICD
1827:ICD
1757:189
1684:doi
1637:doi
1579:doi
1539:doi
1503:doi
1451:doi
1283:doi
1248:doi
1180:PMC
1172:doi
1125:doi
936:doi
901:doi
852:doi
797:doi
758:doi
720:doi
680:doi
573:doi
515:not
115:by
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