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Lumma, William C.; Wohl, Ronald A.; Davey, David D.; Argentieri, Thomas M.; DeVita, Robert J.; Gomez, Robert P.; Jain, Vijay K.; Marisca, Anthony J.; Morgan, Thomas K. (1987). "Rational design of 4-benzamides as class III antiarrhythmic agents". Journal of
Medicinal Chemistry 30 (5): 755–758.
431:) and mesyl chloride gives the sulfonamide, Ethyl 4-(Methylsulfonamido)benzoate . Base saponification followed by the removal of the water from the reaction mixture gives 4-benzoic acid sodium salt (
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InChI=1S/C14H23N3O3S/c1-4-17(5-2)11-10-15-14(18)12-6-8-13(9-7-12)16-21(3,19)20/h6-9,16H,4-5,10-11H2,1-3H3,(H,15,18)
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InChI=1/C14H23N3O3S/c1-4-17(5-2)11-10-15-14(18)12-6-8-13(9-7-12)16-21(3,19)20/h6-9,16H,4-5,10-11H2,1-3H3,(H,15,18)
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Except where otherwise noted, data are given for materials in their
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The reaction between
Benzocaine (Ethyl 4-Aminobenzoate) (
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506:. You can help Knowledge (XXG) by
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44:--4-(methanesulfonamido)benzamide
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362:(at 25 °C , 100 kPa).
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479:(1985 to Schering A.G.).
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476:U.S. patent 4,544,654
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17:Sematilide
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