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Sheena Radford

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intermediates of protein folding and in amyloid formation. A second research focus is on the folding of outer membrane proteins of Gram-negative organisms. Understanding the mechanics of how these proteins fold will help derive new antibiotics. A third arm looks at how the shelf life of pharmaceutical drugs could be extended.
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One major research focus is the role of protein misfolding in the onset of amyloidogenic diseases, including dialysis-related amyloidosis, Alzheimer's, Parkinson's and Type II diabetes. This has been done with the use of native mass spectrometry, NMR and single molecule methods to characterize
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in 1995, progressing to Reader in 1998 and Professor in 2000. She became the deputy director of the Astbury Centre for Structural Molecular Biology in 2009 then Director in 2012 - 2021. Radford's research investigates
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Radford was a postdoc and Royal Society University Research Fellow at the University of Oxford, then worked as a Lecturer in Biochemistry and Molecular Biology at the
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disease. Her multi-disciplinary research focuses include such disciplines as biochemistry, chemistry and medicine.
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Domains and conformational flexibility in the catalytic mechanism of the 2-oxo acid dehydrogenase complexes
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Domains and conformational flexibility in the catalytic mechanism of the 2-oxo acid dehydrogenase complexes
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https://biologicalsciences.leeds.ac.uk/biological-sciences/staff/127/professor-sheena-radford
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in 1987. Radford completed a post-doctoral fellowship at the University of Oxford.
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2024, International Member of the National Academy of Sciences, USA
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and a Royal Society Research Professor in the Astbury Centre for
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https://astbury.leeds.ac.uk/people/professor-sheena-radford/
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Fellows of the Academy of Medical Sciences (United Kingdom)
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2022, Doctorate honoris causa from the University of Liège
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Officer of the Most Excellent Order of the British Empire
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Folding proteins – from Astbury to Amyloid and Ageing
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is a British biophysicist, and Astbury Professor of
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University of Cambridge. 743: 285:2014, Fellow of the Royal Society (FRS) 1114:Alumni of the University of Birmingham 1010:"Professor Sheena Radford FMedSci FRS" 983:"Professor Sheena Radford FRS FMedSci" 298:(joint with Professor Alison Ashcroft) 273:(joint with Professor Alison Ashcroft) 271:American Society for Mass Spectrometry 1119:Alumni of the University of Cambridge 7: 1109:Academics of the University of Leeds 876: 874: 847: 845: 843: 841: 778:10.1093/ww/9780199540884.013.U281947 1089:Female fellows of the Royal Society 906:Radford, Sheena Elizabeth (1987). 14: 759:"Radford, Prof. Sheena Elizabeth" 269:2009, Ron Hites Award from the 858:biologicalsciences.leeds.ac.uk 1: 798:Sheena Radford's publications 288:2014, Honorary member of the 1099:Members of Academia Europaea 1079:Fellows of the Royal Society 834:https://astbury.leeds.ac.uk/ 785:UK public library membership 188:Journal of Molecular Biology 157:http://sheena-radford-lab.uk 991:Academy of Medical Sciences 290:British Biophysical Society 278:Academy of Medical Sciences 1140: 296:Royal Society of Chemistry 258:Royal Society of Chemistry 144: 72: 804:bibliographic database. 344:(FMedSci) in 2010 and a 263:2007, Elected member of 200:University of Birmingham 169:Sheena Elizabeth Radford 51:University of Birmingham 38:Sheena Elizabeth Radford 806:(subscription required) 770:Oxford University Press 447:Sushantha Bhattacharyya 351:Radford is a member of 204:University of Cambridge 56:University of Cambridge 358:Radford was appointed 340:Radford was elected a 1084:British biophysicists 946:. University of Leeds 364:2020 Birthday Honours 852:biologicalsciences. 301:2018, Fellow of the 276:2010, Fellow of the 118:University of Oxford 16:British biophysicist 970:0000-0002-3079-8039 886:facultyopinions.com 733:Jean-Marie Tarascon 718:Philippe Sansonetti 662:Demetri Terzopoulos 303:Biophysical Society 246:Biochemical Society 225:protein aggregation 216:University of Leeds 210:Career and research 184:University of Leeds 113:University of Leeds 1055:The London Gazette 997:on 6 October 2014. 930:uk.bl.ethos.236036 239:Awards and honours 92:Structural biology 783:(Subscription or 741: 740: 612:Karalyn Patterson 567:Vladimir Markovic 512:Geoffrey Grimmett 309:Academia Europaea 180:Molecular Biology 166: 165: 74:Scientific career 1131: 1060: 1059: 1046: 1040: 1039: 1037: 1035: 1024: 1018: 1017: 1005: 999: 998: 993:. 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London: 787:required.) 703:Steven Chu 698:Chunli Bai 672:Tony Watts 647:Alan Soper 622:Randy Read 497:Liam Dolan 370:References 177:Structural 173:Biophysics 87:Biophysics 68:Alan Berry 914:cam.ac.uk 765:Who's Who 627:David Ron 492:John Dick 194:Education 922:53606268 891:14 March 863:14 March 768:(online 411:elected 1034:10 June 950:10 June 823:YouTube 681:Foreign 420:Fellows 413:in 2014 407:of the 405:Fellows 229:amyloid 149:Website 968:  928:  920:  802:Scopus 320:2021, 313:2020, 256:2005, 244:1996, 139:(1987) 137:  128:Thesis 80:Fields 65:Spouse 966:ORCID 926:EThOS 317:(OBE) 1036:2014 952:2014 918:OCLC 893:2021 865:2021 265:EMBO 227:and 34:Born 821:on 774:doi 1070:: 1052:. 985:. 924:. 912:. 884:. 873:^ 856:. 840:^ 762:. 746:^ 355:. 348:. 223:, 190:. 1038:. 954:. 932:. 895:. 867:. 780:. 776:: 397:e 390:t 383:v

Index

University of Birmingham
University of Cambridge
Biophysics
Structural biology
Protein folding
University of Leeds
University of Oxford
Thesis
Domains and conformational flexibility in the catalytic mechanism of the 2-oxo acid dehydrogenase complexes
https://biologicalsciences.leeds.ac.uk/biological-sciences/staff/127/professor-sheena-radford
http://sheena-radford-lab.uk
https://astbury.leeds.ac.uk/people/professor-sheena-radford/
Biophysics
Structural
Molecular Biology
University of Leeds
Journal of Molecular Biology
University of Birmingham
University of Cambridge
University of Leeds
protein folding
protein aggregation
amyloid
Biochemical Society
Colworth Medal
Royal Society of Chemistry
EMBO
American Society for Mass Spectrometry
Academy of Medical Sciences
British Biophysical Society

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