Skin cancer - Knowledge (XXG)

1107: 976:) is a technique used to remove the cancer with the least amount of surrounding tissue and the edges are checked immediately to see if tumor is found. This provides the opportunity to remove the least amount of tissue and provide the best cosmetically favorable results. This is especially important for areas where excess skin is limited, such as the face. Cure rates are equivalent to wide excision. Special training is required to perform this technique. An alternative method is 724: 421: 402: 54: 929:) might be indicated. In the case of an elderly frail man with multiple complicating medical problems, a difficult to excise basal-cell cancer of the nose might warrant radiation therapy (slightly lower cure rate) or no treatment at all. Topical chemotherapy might be indicated for large superficial basal-cell carcinoma for good cosmetic outcome, whereas it might be inadequate for invasive nodular 584:

mole. Other signs are the appearance of a new mole during adulthood or pain, itching, ulceration, redness around the site, or bleeding at the site. An often-used mnemonic is "ABCDE", where A is for "asymmetrical", B for "borders" (irregular: "Coast of Maine sign"), C for "color" (variegated), D for "diameter" (larger than 6 mm – the size of a pencil eraser) and E for "evolving."

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and maximize cosmetic outcome of the reconstruction. Pedicled skin flaps are a method of transferring skin with an intact blood supply from a nearby region of the body. An example of such reconstruction is a pedicled forehead flap for the repair of a large nasal skin defect. Once the flap develops a source of blood supply form its new bed, the vascular pedicle can be detached.

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grafting: split thickness and full thickness. In a split thickness skin graft, a shaver is used to shave a layer of skin from the abdomen or thigh. The donor site regenerates skin and heals over a period of two weeks. In a full thickness skin graft, a segment of skin is totally removed and the donor site needs to be sutured closed.

263:. The first two, along with a number of less common skin cancers, are known as nonmelanoma skin cancer (NMSC). Basal-cell cancer grows slowly and can damage the tissue around it but is unlikely to spread to distant areas or result in death. It often appears as a painless raised area of skin that may be shiny with 343:

are basal-cell cancers and 20% squamous-cell skin cancers. Basal-cell and squamous-cell skin cancers rarely result in death. In the United States, they were the cause of less than 0.1% of all cancer deaths. Globally in 2012, melanoma occurred in 232,000 people and resulted in 55,000 deaths. White people in

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metastasize more frequently than BCCs. Even then, the metastasis rate is quite low, with the exception of SCC of the lip or ear, and in people who are immunosuppressed. Melanoma are the least frequent of the three common skin cancers. They frequently metastasize, and can cause death once they spread.

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More than 3.5 million cases of skin cancer are diagnosed annually in the United States, which makes it the most common form of cancer in that country. One in five Americans will develop skin cancer at some point of their lives. The most common form of skin cancer is basal-cell carcinoma, followed by

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is effective and thus recommended to prevent melanoma and squamous-cell carcinoma. There is little evidence that it is effective in preventing basal-cell carcinoma. Other advice to reduce rates of skin cancer includes avoiding sunburn, wearing protective clothing, sunglasses and hats, and attempting

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Approximately 2,000 people die from basal or squamous cell skin cancers (non-melanoma skin cancers) in the United States each year. The rate has dropped in recent years. Most of the deaths happen to people who are elderly and might not have seen a doctor until the cancer had spread; and people with

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Local skin flaps are a method of closing defects with tissue that closely matches the defect in color and quality. Skin from the periphery of the defect site is mobilized and repositioned to fill the deficit. Various forms of local flaps can be designed to minimize disruption to surrounding tissues

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radiation via direct DNA damage. However malignant melanoma is predominantly caused by UVA radiation via indirect DNA damage. The indirect DNA damage is caused by free radicals and reactive oxygen species. Research indicates that the absorption of three sunscreen ingredients into the skin, combined

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are another common source of ultraviolet radiation. For melanomas and basal-cell cancers, exposure during childhood is particularly harmful. For squamous-cell skin cancers, total exposure, irrespective of when it occurs, is more important. Between 20% and 30% of melanomas develop from moles. People

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The mortality rate of basal-cell and squamous-cell carcinoma is around 0.3%, causing 2000 deaths per year in the US. In comparison, the mortality rate of melanoma is 15–20% and it causes 6500 deaths per year. Even though it is much less common, malignant melanoma is responsible for 75% of all skin

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Skin cancer is the most common form of cancer, globally accounting for at least 40% of cancer cases. The most common type is nonmelanoma skin cancer, which occurs in at least 2–3 million people per year. This is a rough estimate; good statistics are not kept. Of nonmelanoma skin cancers, about 80%

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Currently, surgical excision is the most common form of treatment for skin cancers. The goal of reconstructive surgery is the restoration of normal appearance and function. The choice of technique in reconstruction is dictated by the size and location of the defect. Excision and reconstruction of

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It is important to limit sun exposure and to avoid tanning beds, because they both involve UV light. UV light is known to damage skin cells by mutating their DNA. The mutated DNA can cause tumors and other growths to form on the skin. Further, there are other risk factors beside just UV exposure.

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Most melanoma consist of various colours from shades of brown to black. A small number of melanoma are pink, red or fleshy in colour; these are called amelanotic melanoma and tend to be more aggressive. Warning signs of malignant melanoma include change in the size, shape, color or elevation of a

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or spectroscopy and can be used by a diagnostician to aid in the detection of skin cancer. CAD systems have been found to be highly sensitive in the detection of melanoma, but have a high false-positive rate. There is not yet enough evidence to recommend CAD as compared to traditional diagnostic

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Basal-cell carcinomas are most commonly present on sun-exposed areas of the skin, especially the face. They rarely metastasize and rarely cause death. They are easily treated with surgery or radiation. Squamous-cell skin cancers are also common, but much less common than basal-cell cancers. They

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When skin defects are small in size, most can be repaired with simple repair where skin edges are approximated and closed with sutures. This will result in a linear scar. If the repair is made along a natural skin fold or wrinkle line, the scar will be hardly visible. Larger defects may require

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In February 2024, the Food and Drug Administration approved the first cancer treatment that uses tumor-infiltrating lymphocytes, also called TIL therapy, specifically for melanomas that have not improved with other treatments. Additionally, scientists are testing a vaccine designed to match the

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in the skin, if applied in too little quantity and too infrequently. However, the researchers add that newer creams often do not contain these specific compounds, and that the combination of other ingredients tends to retain the compounds on the surface of the skin. They also add that frequent

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In the US in 2008, 59,695 people were diagnosed with melanoma, and 8,623 people died from it. In Australia more than 12,500 new cases of melanoma are reported each year, out of which more than 1,500 die from the disease. Australia has the highest per capita incidence of melanoma in the world.

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Skin grafting is patching of a defect with skin that is removed from another site in the body. The skin graft is sutured to the edges of the defect, and a bolster dressing is placed atop the graft for seven to ten days, to immobilize the graft as it heals in place. There are two forms of skin

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squamous cells and form round nodules with concentric, laminated layers, called "cell nests" or "epithelial/keratinous pearls". The surrounding stroma is reduced and contains inflammatory infiltrate (lymphocytes). Poorly differentiated squamous carcinomas contain more pleomorphic cells and no

1093:. Around 434,000 people receive treatment for non-melanoma skin cancers and 10,300 are treated for melanoma. Melanoma is the most common type of cancer in people between 15 and 44 years in both countries. The incidence of skin cancer has been increasing. The incidence of melanoma among 563:) can be seen within the tumor. Crusting and bleeding in the center of the tumor frequently develops. It is often mistaken for a sore that does not heal. This form of skin cancer is the least deadly, and with proper treatment can be eliminated, often without significant scarring. 1070:

The survival rate for people with melanoma depends upon when they start treatment. The cure rate is very high when melanoma is detected in early stages, when it can easily be removed surgically. The prognosis is less favorable if the melanoma has spread to other parts of the

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appear to be effective methods of preventing melanoma and squamous-cell skin cancer. It is not clear if sunscreen affects the risk of basal-cell cancer. Nonmelanoma skin cancer is usually curable. Treatment is generally by surgical removal but may, less commonly, involve

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Split thickness grafts can be used to repair larger defects, but the grafts are inferior in their cosmetic appearance. Full thickness skin grafts are more acceptable cosmetically. However, full thickness grafts can only be used for small or moderate sized defects.

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are caused by sun exposure, but it can happen occasionally. On dogs, the nose and pads of the feet contain sensitive skin and no fur to protect from the sun. Also, cats and dogs with thin or light-colored coats are at a higher risk of sun damage over their entire

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residents of European descent in 1995 was 77.7 cases per 100,000 people per year, and was predicted to increase in the 21st century because of "the effect of local stratospheric ozone depletion and the time lag from sun exposure to melanoma development."

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or 5-fluorouracil) and cryotherapy (freezing the cancer off) can provide adequate control of the disease; all of them, however, may have lower overall cure rates than certain type of surgery. Other modalities of treatment such as photodynamic therapy,

4531: 4512: 654:). It is believed that tanning beds are the cause of hundreds of thousands of basal and squamous-cell skin cancer. The World Health Organization now places people who use artificial tanning beds in its highest risk category for skin cancer. 531:, such as jagged edges to the mole, enlargement of the mole, changes in color, the way it feels or if it bleeds. Other common signs of skin cancer can be painful lesion that itches or burns and large brownish spot with darker speckles. 3493:

Chang YJ, Myung SK, Chung ST, Kim Y, Lee EH, Jeon YJ, et al. (2011). "Effects of vitamin treatment or supplements with purported antioxidant properties on skin cancer prevention: a meta-analysis of randomized controlled trials".

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There is insufficient evidence that optical coherence tomography (OCT) is useful in diagnosing melanoma or squamous cell carcinoma. OCT may have a role in diagnosing basal cell carcinoma but more data is needed to support this.

810:, Raman spectroscopy, fluorescence spectroscopy, terahertz spectroscopy, optical coherence tomography, the multispectral imaging technique, thermography, electrical bio-impedance, tape stripping and computer-aided analysis. 575:. Ulceration and bleeding may occur. When SCC is not treated, it may develop into a large mass. Squamous-cell is the second most common skin cancer. It is dangerous, but not nearly as dangerous as a melanoma. 247:

to other parts of the body. It occurs when skin cells grow uncontrollably, forming malignant tumors. The primary cause of skin cancer is prolonged exposure to ultraviolet (UV) radiation from the sun or tanning

831:(HFUS) is of unclear usefulness in the diagnosis of skin cancer. There is insufficient evidence for reflectance confocal microscopy to diagnose basal cell or squamous cell carcinoma or any other skin cancers. 1880:

To date, skin cancer is the most frequently diagnosed form of oncopathology in humans and represents a wide range of malignancies. More than 40% of the total number of diagnosed cancers in the world are skin

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A meta-analysis of skin cancer prevention in high risk individuals found evidence that topical application of T4N5 liposome lotion reduced the rate of appearance of basal cell carcinomas in people with

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have the highest rates of melanoma in the world. The three main types of skin cancer have become more common in the last 20 to 40 years, especially regions where the population is predominantly White.

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Melanoma is the fifth most common cancer in the UK (around 13,300 people were diagnosed with melanoma in 2011), and the disease accounts for 1% all cancer deaths (around 2,100 people died in 2012).

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A paper published in January 2022 showed that a vaccine that stimulates the production of a protein critical to the skin's antioxidant network could reinforce people's defenses against skin cancer.

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have not been found to have an effect in prevention. Evidence for reducing melanoma risk from dietary measures is tentative, with some supportive epidemiological evidence, but no clinical trials.

1616:"Global, regional, and national incidence, prevalence, and years lived with disability for 310 diseases and injuries, 1990-2015: a systematic analysis for the Global Burden of Disease Study 2015" 633:(birthmarks or moles) of varying size which are either present at birth, or appear within 6 months of birth. Nevi larger than 20 mm (3/4") in size are at higher risk for becoming cancerous. 4613: 1232:

Although the rates of many cancers in the United States is falling, the incidence of melanoma keeps growing, with approximately 68,729 melanomas diagnosed in 2004 according to reports of the

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Their disposal tends to be similar to that of normal epidermis: immature/basal cells at the periphery, becoming more mature to the centre of the tumor masses. Tumor cells transform into

271:. Squamous-cell skin cancer is more likely to spread. It usually presents as a hard lump with a scaly top but may also form an ulcer. Melanomas are the most aggressive. Signs include a 4159:

From 1982 to 2007 melanoma diagnoses increased by around 50%. From 1998 to 2007, GP consultations to treat non-melanoma skin cancer increased by 14%, to reach 950,000 visits each year.

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Ultraviolet radiation from sun exposure is the primary environmental cause of skin cancer. This can occur in professions such as farming. Other risk factors that play a role include:

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Skin cancers result in 80,000 deaths a year as of 2010, 49,000 of which are due to melanoma and 31,000 of which are due to non-melanoma skin cancers. This is up from 51,000 in 1990.

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formed by adjacent thymine bases, or by adjacent cytosine bases, are frequent types of DNA damage induced by UV. Human skin cells are capable of repairing most UV-induced damage by

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repair with a skin graft, local skin flap, pedicled skin flap, or a microvascular free flap. Skin grafts and local skin flaps are by far more common than the other listed choices.

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carcinomas are most often rapidly growing, non-tender red, purple or skin colored bumps that are not painful or itchy. They may be mistaken for a cyst or another type of cancer.

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may be used to improve quality of life. Melanoma has one of the higher survival rates among cancers, with over 86% of people in the UK and more than 90% in the United States

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A malignant epithelial tumor that primarily originates in the epidermis, in squamous mucosa or in areas of squamous metaplasia is referred to as a squamous-cell carcinoma.

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Note the pearly translucency to fleshy color, tiny blood vessels on the surface, and sometimes ulceration which can be characteristics. The key term is translucency.

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Treatment is dependent on the specific type of cancer, location of the cancer, age of the person, and whether the cancer is primary or a recurrence. For a small

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Lin JS, Eder M, Weinmann S (February 2011). "Behavioral counseling to prevent skin cancer: a systematic review for the U.S. Preventive Services Task Force".

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These are commonly asymmetrical in shape and/or pigment distribution, with an irregular border, color variation, and often greater than 6 mm diameter.

6923: 5571: 1276:(cancerous), exist in cats and dogs. Approximately 20–40% of primary skin tumors are malignant in dogs and 50–65% are malignant in cats. Not all forms of 2347:

Bickle K, Glass LF, Messina JL, Fenske NA, Siegrist K (March 2004). "Merkel cell carcinoma: a clinical, histopathologic, and immunohistochemical review".

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Squamous-cell skin cancer (SCC) is commonly a red, scaling, thickened patch on sun-exposed skin. Some are firm hard nodules and dome shaped like

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Vos T, Allen C, Arora M, Barber RM, Bhutta ZA, Brown A, et al. (GBD 2015 Disease Injury Incidence Prevalence Collaborators) (October 2016).

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and form sheets or compact masses which invade the subjacent connective tissue (dermis). In well differentiated carcinomas, tumor cells are

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Wang H, Naghavi M, Allen C, Barber RM, Bhutta ZA, Carter A, et al. (GBD 2015 Mortality Causes of Death Collaborators) (October 2016).

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exhibit one of the highest rates of skin cancer incidence in the world, almost four times the rates registered in the United States, the

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facial skin cancers are generally more challenging due to the presence of highly visible and functional anatomic structures in the face.

6669: 6646: 6551: 1106: 844: 1913: 1075:. As of 2003 the overall five-year cure rate with Mohs' micrographic surgery was around 95 percent for recurrent basal cell carcinoma. 6913: 6282: 5516: 1552: 6940: 6873: 6868: 6809: 6804: 5915: 5448: 5443: 3801:"Epidermal Radionuclide Therapy: Dermatological High-Dose-Rate Brachytherapy for the Treatment of Basal and Squamous Cell Carcinoma" 2223: 3939: 4471: 1799:"Changing trends in the disease burden of non-melanoma skin cancer globally from 1990 to 2019 and its predicted level in 25 years" 7013: 6631: 6603: 6182: 6177: 5820: 5511: 5478: 5428: 4661: 4355: 3010:

Ferrante di Ruffano L, Dinnes J, Deeks JJ, Chuchu N, Bayliss SE, Davenport C, et al. (Cochrane Skin Group) (December 2018).

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Hill R, Healy B, Holloway L, Kuncic Z, Thwaites D, Baldock C (March 2014). "Advances in kilovoltage x-ray beam dosimetry".

1318: 286:. This exposure increases the risk of all three main types of skin cancer. Exposure has increased, partly due to a thinner 6962: 6794: 6664: 6566: 5597: 5463: 5423: 4976: 4415: 3953: 3434: 2287: 2092: 471: 6992: 6903: 6814: 5908: 5830: 5453: 5268: 5198: 4067: 1277: 1258: 890:

Eating certain foods may decrease the risk of sunburns but this is much less than the protection provided by sunscreen.

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Saladi RN, Nektalova T, Fox JL (January 2010). "Induction of skin carcinogenicity by alcohol and ultraviolet light".

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Dinnes J, Deeks JJ, Chuchu N, Saleh D, Bayliss SE, Takwoingi Y, et al. (Cochrane Skin Group) (December 2018).

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Dinnes J, Deeks JJ, Chuchu N, Matin RN, Wong KY, Aldridge RB, et al. (Cochrane Skin Group) (December 2018).

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Skin cancer is the most commonly diagnosed form of cancer in humans. There are three main types of skin cancers:

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Chiao EY, Krown SE (September 2003). "Update on non-acquired immunodeficiency syndrome-defining malignancies".

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Ferrante di Ruffano L, Takwoingi Y, Dinnes J, Chuchu N, Bayliss SE, Davenport C, et al. (December 2018).

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Basal-cell skin cancer (BCC) usually presents as a raised, smooth, pearly bump on the sun-exposed skin of the

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Cakir BÖ, Adamson P, Cingi C (November 2012). "Epidemiology and economic burden of nonmelanoma skin cancer".

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Kütting B, Drexler H (December 2010). "UV-induced skin cancer at workplace and evidence-based prevention".

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Narayanamurthy V, Padmapriya P, Noorasafrin A, Pooja B, Hema K, Firus Khan AY, et al. (August 2018).

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that has changed in size, shape, color, has irregular edges, has more than one color, is itchy or bleeds.

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squamous cell carcinoma. Unlike for other cancers, there exists no basal and squamous cell skin cancers

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with lighter skin are at higher risk as are those with poor immune function such as from medications or

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Leiter U, Garbe C (2008). "Epidemiology of Melanoma and Nonmelanoma Skin Cancer—The Role of Sunlight".

249: 4437: 3574:"Titanium dioxide and zinc oxide nanoparticles in sunscreens: focus on their safety and effectiveness" 2238: 7018: 6432: 6378: 6205: 6051: 5688: 5661: 5656: 5651: 5412: 5253: 4939: 4784: 4774: 4654: 3757: 3293: 2915: 962: 930: 392: 166: 3452:

Bibbins-Domingo K, Grossman DC, Curry SJ, Davidson KW, Ebell M, Epling JW, et al. (July 2016).

3395: 2733:"Skin cancer in organ transplant recipients: effects of immunosuppressive medications on DNA repair" 850:

The risk of developing skin cancer can be reduced through a number of measures including decreasing

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Fair skin, prolonged history of sunburns, moles, and family history of skin cancer are just a few.

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Commonly presents as a red, crusted, or scaly patch or bump. Often a very rapidly growing tumor.

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Jensen JD, Wing GJ, Dellavalle RP (November–December 2010). "Nutrition and melanoma prevention".

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Dinnes J, Bamber J, Chuchu N, Bayliss SE, Takwoingi Y, Davenport C, et al. (December 2018).

2762: 2662: 2555: 2413: 2269: 2044: 715:, a process that protects against skin cancer, but may be inadequate at high levels of exposure. 643: 372: 90: 5538: 4618: 2839: 6613: 6546: 6491: 6391: 6348: 5810: 5693: 5553: 5323: 5172: 5147: 5022: 5012: 4924: 4738: 4587: 4296: 4192: 4120: 4037: 3998: 3891: 3868:

Maverakis E, Cornelius LA, Bowen GM, Phan T, Patel FB, Fitzmaurice S, et al. (May 2015).

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Dermatoscopy may be useful in diagnosing basal cell carcinoma in addition to skin inspection.

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Kuschal C, Thoms KM, Schubert S, Schäfer A, Boeckmann L, Schön MP, Emmert S (January 2012).

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recommends that people between 9 and 25 years of age be advised to avoid ultraviolet light.

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BCC and SCC often carry a UV-signature mutation indicating that these cancers are caused by

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Bath-Hextall F, Leonardi-Bee J, Somchand N, Webster A, Delitt J, Perkins W (October 2007).

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Saladi RN, Persaud AN (January 2005). "The causes of skin cancer: a comprehensive review".

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Lozano R, Naghavi M, Foreman K, Lim S, Shibuya K, Aboyans V, et al. (December 2012).

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Non-invasive skin cancer detection methods include photography, dermatoscopy, sonography,

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Burnett ME, Wang SQ (April 2011). "Current sunscreen controversies: a critical review".

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Mata DA, Williams EA, Sokol E, Oxnard GR, Fleischmann Z, Tse JY, Decker B (March 2022).

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https://www.mayoclinic.org/diseases-conditions/skin-cancer/symptoms-causes/syc-20377605

2157: 1953: 1928: 1825: 1798: 1774: 1747: 1693: 1666: 1642: 1615: 1110: 1011: 884: 851: 800: 784: 773: 752:, or may be ulcerated with irregular borders. Microscopically, tumor cells destroy the 704: 560: 495: 264: 99: 66: 4272: 4173:"Incidence of malignant melanoma in Auckland, New Zealand: highest rates in the world" 4115: 4090: 3769: 2533: 2360: 1683: 1632: 987:

In the case of disease that has spread (metastasized), further surgical procedures or

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Balk SJ (March 2011). "Ultraviolet radiation: a hazard to children and adolescents".

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Gordon R (August 2013). "Skin cancer: an overview of epidemiology and risk factors".

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There are a variety of different skin cancer symptoms. These include changes in the

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Computer-assisted diagnosis devices have been developed that analyze images from a

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Alcohol consumption, specifically excessive drinking increase the risk of sunburns.

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Kanavy HE, Gerstenblith MR (December 2011). "Ultraviolet radiation and melanoma".

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are often used in sunscreen to provide broad protection from UVA and UVB ranges.

869:

There is insufficient evidence either for or against screening for skin cancers.

6878: 6445: 6363: 6326: 5318: 5193: 5017: 4957: 4779: 4702: 4582: 3800: 2494: 1986: 1866: 1849: 1082: 1015: 768: 739: 696: 647: 592: 348: 287: 160: 83: 5353: 4407: 3219: 1944: 1815: 6386: 6061: 5223: 5205: 4962: 4811: 4748: 4712: 3305: 3174: 3125: 3076: 3027: 2787:"Deciphering UV-induced DNA Damage Responses to Prevent and Treat Skin Cancer" 2135: 1505: 1072: 1026: 1019: 1007: 995: 880: 727: 679:

Deliberate exposure of sensitive skin not normally exposed to sunlight during

540: 520: 244: 236: 103: 17: 4106: 4059: 3993: 3976: 1875: 6656: 6511: 6496: 6440: 6225: 5900: 5640: 5403: 5388: 4981: 4867: 4852: 4733: 4717: 4525: 4521: 4025: 3934: 3666:"Interventions for preventing non-melanoma skin cancers in high-risk groups" 3641: 3624: 1452: 1435: 1273: 1078: 1033:

unique genetic details of a patient's cancer in an advanced clinical trial.

1003: 949: 899: 855: 839: 749: 344: 307: 189: 4300: 4196: 4124: 4041: 3895: 3777: 3709: 3650: 3609: 3558: 3515: 3479: 3470: 3453: 3412: 3356: 3348: 3313: 3262: 3227: 3192: 3143: 3094: 3045: 2996: 2947: 2820: 2758: 2717: 2658: 2608: 2551: 2502: 2467: 2409: 2368: 2265: 2143: 2040: 2005: 1962: 1927:

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937:. In general, melanoma is poorly responsive to radiation or chemotherapy. 640:

based on their appearance, and can develop into squamous-cell skin cancer.

6195: 6094: 5081: 4971: 4862: 4821: 4806: 4679: 4671: 3812: 2239:"Sunscreen enhancement of UV-induced reactive oxygen species in the skin" 1114: 1094: 994:

Treatments for metastatic melanoma include biologic immunotherapy agents

731: 684: 552: 430: 296: 260: 135: 79: 4627: 3870:"Metastatic melanoma - a review of current and future treatment options" 1764: 5105: 4872: 4857: 4188: 3590: 2928: 2682:"Malignant and noninvasive skin tumours in renal transplant recipients" 2680:

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2518:"Prevalence of UV Mutational Signatures Among Cutaneous Primary Tumors" 1746:

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779:

A molecular factor involved in the disease process is mutation in gene

614: 331:. In those people whose disease has spread to other areas of the body, 4504: 3690: 3507: 3376: 3374: 2802: 2590: 902:

taken by mouth may have a skin protective benefit in people following

6305: 5943: 5935: 4743: 4675: 4622: 4516: 1269: 1265: 1090: 977: 926: 796: 300: 232: 4256: 2887: 2870: 439: 3012:"Optical coherence tomography for diagnosing skin cancer in adults" 6317: 5846: 5167: 2785:

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International Archives of Occupational and Environmental Health

3625:"β-Carotene and other carotenoids in protection from sunlight" 2300:"What You Need To Know About: Melanoma and Other Skin Cancers" 1354:

Primary Care: The Art and Science of Advanced Practice Nursing

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that has changed in size, shape, color, or has irregular edges

27:

Medical condition involving uncontrolled growth of skin cells

4024:

Jerant AF, Johnson JT, Sheridan CD, Caffrey TJ (July 2000).

1119: 1117:

and other skin cancers per 100,000 inhabitants in 2004

672:

for example increases the risk approximately 200 times, and

438: 419: 400: 306:

Decreasing exposure to ultraviolet radiation and the use of

1086: 1547:. World Health Organization. 2014. pp. Chapter 5.14. 921:

in a young person, the treatment with the best cure rate (

622:

infections increase the risk of squamous-cell skin cancer.

4326:"Key statistics for basal and squamous cell skin cancers" 506:

with a 60-minute exposure to UV, leads to an increase of

3911:"How to Avoid One of the Deadliest Forms of Skin Cancer" 3845:

Greenfield's Surgery: Scientific Principles And Practice

980:

and can be performed by a pathologist not familiar with

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to avoid sun exposure or periods of peak exposure. The

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527:

in the skin, discolored skin, and changes in existing

511:

re-application reduces the risk of radical formation.

98:: painless raised area of skin that may be shiny with 4360:

U.S. Centers for Disease Control and Prevention (CDC)

3243:

Photodermatology, Photoimmunology & Photomedicine

2904:"Skin cancer detection using non-invasive techniques" 1575:"UV protection and sunscreens: what to tell patients" 4494: 2834: 2832: 2830: 1434:

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Melanocytic tumors of uncertain malignant potential

5080: 4995: 4948: 4906: 4881: 4845: 4767: 4726: 4693: 4686: 4573: 4498: 218: 210: 195: 184: 172: 159: 141: 123: 89: 73: 46: 6153:Porokeratotic eccrine ostial and dermal duct nevus 2846:(3rd ed.). Universitatii St., Iasi, Romania. 2382:Narayanan DL, Saladi RN, Fox JL (September 2010). 4171:Jones WO, Harman CR, Ng AK, Shaw JH (July 1999). 2626:. Chestnut Hill, MA: Harvard Health Publications. 2237:Hanson KM, Gratton E, Bardeen CJ (October 2006). 278:More than 90% of cases are caused by exposure to 2193:. Jones & Bartlett Publishers. p. 271. 1797:Hu W, Fang L, Ni R, Zhang H, Pan G (July 2022). 854:and mid-day sun exposure, increasing the use of 4628:Skin cancer procedures: text, images and videos 3724:"Possibility of vaccine to prevent skin cancer" 2124:Facial Plastic Surgery Clinics of North America 1494:Facial Plastic Surgery Clinics of North America 664:medications increases the risk of skin cancer. 4026:"Early detection and treatment of skin cancer" 1313: 1311: 1309: 1307: 1305: 1303: 1301: 1299: 1297: 1295: 748:Macroscopically, the tumor is often elevated, 239:. They are due to the development of abnormal 188:Decreasing exposure to ultraviolet radiation, 6723: 6290: 5916: 5816:Inflammatory linear verrucous epidermal nevus 5369: 5054: 4655: 4089:Wong CS, Strange RC, Lear JT (October 2003). 2063:"SEER Stat Fact Sheets: Melanoma of the Skin" 636:Chronic non-healing wounds. These are called 8: 1573:Jou PC, Feldman RJ, Tomecki KJ (June 2012). 5572:Aggressive digital papillary adenocarcinoma 3670:The Cochrane Database of Systematic Reviews 3163:The Cochrane Database of Systematic Reviews 3114:The Cochrane Database of Systematic Reviews 3065:The Cochrane Database of Systematic Reviews 3016:The Cochrane Database of Systematic Reviews 2967:The Cochrane Database of Systematic Reviews 2441: 2439: 2437: 2435: 2433: 2431: 2429: 2427: 1902:. Malden, MA: Blackwell Pub. pp. 5–6. 1848:Lyakhov PA, Lyakhova UA, Kalita DI (2023). 363:There are three main types of skin cancer: 6730: 6716: 6708: 6530: 6331: 6322: 6297: 6283: 6275: 6016: 5975: 5923: 5909: 5901: 5780: 5636: 5608:Primary cutaneous adenoid cystic carcinoma 5408: 5399: 5376: 5362: 5354: 5177: 5061: 5047: 5039: 4690: 4662: 4648: 4640: 4495: 4250: 4248: 4223:"WHO Disease and injury country estimates" 3629:The American Journal of Clinical Nutrition 3208:Seminars in Cutaneous Medicine and Surgery 2349:Seminars in Cutaneous Medicine and Surgery 1891: 1889: 629:which is characterized by the presence of 52: 43: 4290: 4280: 4114: 3992: 3885: 3699: 3689: 3640: 3599: 3589: 3469: 3394: 3182: 3133: 3084: 3035: 2986: 2937: 2927: 2886: 2810: 2748: 2707: 2697: 2598: 2541: 2399: 1985: 1952: 1865: 1824: 1814: 1773: 1763: 1692: 1682: 1641: 1631: 1590: 1568: 1566: 1564: 1539: 1537: 1535: 1533: 1531: 1529: 1527: 1525: 1523: 1487: 1485: 1483: 1481: 1479: 1477: 1475: 1473: 1471: 1451: 1390: 1388: 1386: 1384: 1382: 1380: 1378: 1346: 1344: 940:For low-risk disease, radiation therapy ( 6760:Attention deficit hyperactivity disorder 5990:Template:Soft tissue tumors and sarcomas 5826:Pigmented hairy epidermal nevus syndrome 4612:) is being considered for deletion. See 3578:Nanotechnology, Science and Applications 1429: 1427: 1425: 1423: 1421: 377: 267:or may present as a raised area with an 5865:Unilateral palmoplantar verrucous nevus 5138:Melanoma with features of a Spitz nevus 3405:10.7326/0003-4819-154-3-201102010-00009 2871:"Non-melanoma Skin Cancer: Mini Review" 2384:"Ultraviolet radiation and skin cancer" 1748:"Epidemiological trends in skin cancer" 1291: 764:(pink) cytoplasm and central nucleus). 34:Skin Cancer: Recognition and Management 5870:Zosteriform speckled lentiginous nevus 5717:Keratoacanthoma centrifugum marginatum 3975:Boring CC, Squires TS, Tong T (1991). 2780: 2778: 2776: 2336:from the original on 9 September 2013. 2168:from the original on 27 September 2010 1752:Dermatology Practical & Conceptual 6675:Folliculosebaceous-apocrine hamartoma 6211:Giant-cell tumor of the tendon sheath 4320: 4318: 4233:from the original on 11 November 2009 3847:. Baltimore: Williams & Wilkins. 2639:Clinical and Experimental Dermatology 7: 6173:Pleomorphic undifferentiated sarcoma 5486:Nevoid basal-cell carcinoma syndrome 5143:Melanoma with small nevus-like cells 4474:from the original on 2 December 2023 4448:from the original on 16 January 2014 4336:from the original on 10 January 2017 2388:International Journal of Dermatology 2226:from the original on 7 October 2010. 2103:from the original on 17 October 2014 1579:Cleveland Clinic Journal of Medicine 1396:"General Information About Melanoma" 783:that plays an important role in the 650:, and artificial UV radiation (e.g. 627:congenital melanocytic nevi syndrome 371:(squamous-cell carcinoma) (SCC) and 6857:Epidemiology of Alzheimer's disease 6670:Folliculosebaceous cystic hamartoma 6552:Multiple familial trichoepithelioma 4149:from the original on 10 August 2012 3435:"Skin cancer – Symptoms and causes" 2312:from the original on 18 March 2013. 2258:10.1016/j.freeradbiomed.2006.06.011 2246:Free Radical Biology & Medicine 1978:Sunlight, Vitamin D and Skin Cancer 1916:from the original on 29 April 2016. 961:can be found in the discussions of 845:U.S. Preventive Services Task Force 454:Less common skin cancers include: 265:small blood vessels running over it 243:that have the ability to invade or 4070:from the original on 23 March 2010 4048:from the original on 24 July 2008. 3942:from the original on 9 March 2009. 3843:Doherty GM, Mulholland MW (2005). 3572:Smijs TG, Pavel S (October 2011). 3551:10.1016/j.clindermatol.2010.03.026 2850:from the original on 10 March 2009 1896:Marsden J (2008). Rajpar S (ed.). 100:small blood vessel running over it 25: 4616:to help reach a consensus. › 4418:from the original on 30 June 2010 3623:Stahl W, Sies H (November 2012). 2686:Dermatology Research and Practice 2534:10.1001/jamanetworkopen.2022.3833 2329:. American Cancer Society. 2012. 1727:from the original on 25 June 2014 1371:from the original on 20 May 2016. 625:Some genetic syndromes including 65:. Note the pearly appearance and 6632:Tumor of follicular infundibulum 6604:Giant solitary trichoepithelioma 6183:Progressive nodular histiocytoma 6178:Plexiform fibrohistiocytic tumor 5821:Linear verrucous epidermal nevus 3255:10.1111/j.1600-0781.2011.00557.x 2750:10.1111/j.1600-0625.2011.01413.x 2651:10.1111/j.1365-2230.2009.03465.x 2401:10.1111/j.1365-4632.2010.04474.x 2073:from the original on 6 July 2014 2033:10.1097/00001622-200309000-00008 1406:from the original on 5 July 2014 1329:from the original on 5 July 2014 1257:This section is an excerpt from 959:electrodesiccation and curettage 6599:Proliferating trichilemmal cyst 6399:Syringocystadenoma papilliferum 6133:Nevus lipomatosus superficialis 5961:Dermatofibrosarcoma protuberans 5956:dermatofibrosarcoma protuberans 5836:Phakomatosis pigmentokeratotica 4378:"Melanoma facts and statistics" 4139:"Skin Cancer Facts and Figures" 3750:Physics in Medicine and Biology 2869:Kormi SM, Ardehkhani S (2012). 2791:Photochemistry and Photobiology 2190:Epidemiology of Chronic Disease 488:dermatofibrosarcoma protuberans 315:or topical medications such as 6562:Desmoplastic trichoepithelioma 6067:Palisaded encapsulated neuroma 5095:Superficial spreading melanoma 3682:10.1002/14651858.CD005414.pub2 2979:10.1002/14651858.CD011901.pub2 2097:Office for National Statistics 1929:"Light, including ultraviolet" 1319:"Skin Cancer Treatment (PDQ®)" 955:epidermal radioisotope therapy 646:such as X-rays, environmental 367:(basal-cell carcinoma) (BCC), 1: 6665:Basaloid follicular hamartoma 6567:Generalized trichoepithelioma 5598:Microcystic adnexal carcinoma 4977:Clonally transmissible cancer 4273:10.1016/S0140-6736(12)61728-0 3930:"Skin Grafts, Full-Thickness" 3799:Cipriani C, Sedda AF (2012). 2361:10.1016/s1085-5629(03)00087-7 2305:. National Cancer Institute. 2214:Swetter SM (30 August 2010). 1684:10.1016/s0140-6736(16)31012-1 1633:10.1016/S0140-6736(16)31678-6 801:histopathological examination 472:microcystic adnexal carcinoma 460:Paget's disease of the breast 5831:Systematized epidermal nevus 5577:Extramammary Paget's disease 5269:Congenital melanocytic nevus 5199:Pigmented spindle cell nevus 4382:Melanoma Institute Australia 3954:"Skin Cancer Reconstruction" 3928:Khosh MM (2 February 2019). 3805:Therapeutic Nuclear Medicine 2483:Seminars in Oncology Nursing 2460:10.1358/dot.2005.41.1.875777 2158:"How common is skin cancer?" 1278:skin cancer in cats and dogs 1259:Skin cancer in cats and dogs 972:Mohs' micrographic surgery ( 412:Squamous-cell skin carcinoma 110:: hard lump with a scaly top 5998:Template:Myeloid malignancy 5952:Benign fibrous histiocytoma 4332:. American Cancer Society. 4060:"Malignant Melanoma Cancer" 4036:(2): 357–68, 375–6, 381–2. 3770:10.1088/0031-9155/59/6/r183 3383:Annals of Internal Medicine 2495:10.1016/j.soncn.2013.06.002 2021:Current Opinion in Oncology 1987:10.1007/978-0-387-77574-6_8 1867:10.1109/ACCESS.2023.3336289 1357:. F.A. Davis. p. 242. 337:surviving more than 5 years 7040: 6557:Solitary trichoepithelioma 6446:Hidradenoma or Acrospiroma 5804:Nevus comedonicus syndrome 5439:Fibroepithelioma of Pinkus 5121:Acral lentiginous melanoma 5008:Index of oncology articles 3909:Alcorn T (15 April 2024). 3874:Acta Dermato-Venereologica 3220:10.1016/j.sder.2011.08.003 1945:10.1016/j.jaut.2009.11.011 1816:10.1186/s12885-022-09940-3 1440:Chronic Diseases in Canada 1256: 942:external beam radiotherapy 858:, and avoiding the use of 713:nucleotide excision repair 462:, atypical fibroxanthoma, 31: 6627: 6533: 6344:Papillary eccrine adenoma 6191: 6029:Hirsuties coronae glandis 5314: 5306:Dysplastic nevus syndrome 5292: 5264: 5219: 5180: 4227:World Health Organization 4030:American Family Physician 3977:"Cancer statistics, 1991" 3306:10.1007/s00420-010-0532-4 3175:10.1002/14651858.CD013191 3126:10.1002/14651858.cd013188 3077:10.1002/14651858.cd013186 3028:10.1002/14651858.CD013189 2162:World Health Organization 2136:10.1016/j.fsc.2012.10.003 1721:National Cancer Institute 1506:10.1016/j.fsc.2012.07.004 1248:immune system disorders. 1234:National Cancer Institute 948:), topical chemotherapy ( 829:High-frequency ultrasound 567:Squamous-cell skin cancer 369:squamous-cell skin cancer 257:squamous-cell skin cancer 132:squamous-cell skin cancer 60: 51: 6931:Motor vehicle collisions 6697:Neoplasms of the nailbed 6502:Sebaceous nevus syndrome 6414:Apocrine gland carcinoma 5994:Template:Vascular tumors 5799:Schimmelpenning syndrome 5794:Epidermal nevus syndrome 5549:Erythroplasia of Queyrat 5329:Benign melanocytic nevus 5116:Lentigo maligna melanoma 4614:templates for discussion 4438:"Skin cancer statistics" 4356:"Skin Cancer Statistics" 4177:World Journal of Surgery 4143:Cancer Council Australia 4107:10.1136/bmj.327.7418.794 3994:10.3322/canjclin.41.1.19 2737:Experimental Dermatology 1545:World Cancer Report 2014 957:, topical chemotherapy, 7014:Integumentary neoplasia 6647:Birt–Hogg–Dubé syndrome 6542:Malignant pilomatricoma 6251:Keratinizing metaplasia 6143:Connective tissue nevus 6100:Extraskeletal chondroma 6072:Infantile neuroblastoma 5339:Connective tissue nevus 4930:Prostate cancer staging 4894:Paraneoplastic syndrome 4633:7 December 2013 at the 3642:10.3945/ajcn.112.034819 1933:Journal of Autoimmunity 1453:10.24095/hpcdp.29.S1.04 1436:"Ultraviolet radiation" 1067:cancer-related deaths. 967:squamous-cell carcinoma 935:squamous-cell carcinoma 875:antioxidant supplements 705:photochemical reactions 466:, spindle cell tumors, 6780:Cardiovascular disease 6642:Perifollicular fibroma 6594:Trichilemmal carcinoma 6246:Zosteriform metastasis 6148:Midline nevus flammeus 6077:Cutaneous neurofibroma 5679:Pilar sheath acanthoma 4968:Tumor suppressor genes 4935:Gleason grading system 4889:Precancerous condition 4468:"Dogs and Skin Cancer" 4412:Skin Cancer Foundation 4091:"Basal cell carcinoma" 3539:Clinics in Dermatology 3471:10.1001/jama.2016.8465 3349:10.1542/peds.2010-3501 2324:"Melanoma Skin Cancer" 1592:10.3949/ccjm.79a.11110 1220:in the United States. 1209: 742: 736:fine-needle aspiration 535:Basal-cell skin cancer 443: 424: 405: 365:basal-cell skin cancer 253:basal-cell skin cancer 128:Basal-cell skin cancer 63:basal-cell skin cancer 6958:Risky sexual behavior 6742:of medical conditions 6507:Sebaceous hyperplasia 6404:Papillary hidradenoma 6369:Malignant acrospiroma 6310:associated structures 6128:Nevus flammeus nuchae 6047:Solitary neurofibroma 5618:Malignant mixed tumor 5593:Merkel-cell carcinoma 5133:Desmoplastic melanoma 4987:Carcinogenic bacteria 4727:Malignant progression 4282:10536/DRO/DU:30050819 3887:10.2340/00015555-2035 2220:eMedicine Dermatology 1723:. 17 September 2007. 1109: 896:xeroderma pigmentosum 726: 699:of skin cells causes 692:UV-induced DNA damage 670:calcineurin inhibitor 456:Merkel cell carcinoma 442: 423: 404: 280:ultraviolet radiation 146:Ultraviolet radiation 6948:Periodontal diseases 6206:Metastatic carcinoma 6052:Cutaneous meningioma 5712:Generalized eruptive 5689:Seborrheic keratosis 4940:Dukes classification 4366:on 8 September 2012. 3813:10.1007/174_2012_778 3803:. In Baum RP (ed.). 2624:Skin Care and Repair 2216:"Malignant Melanoma" 2099:. 15 November 2011. 1677:(10053): 1459–1544. 1626:(10053): 1545–1602. 963:basal-cell carcinoma 931:basal-cell carcinoma 681:alternative wellness 468:sebaceous carcinomas 393:Basal-cell carcinoma 235:that arise from the 167:poor immune function 6487:Sebaceous carcinoma 6482:Muir–Torre syndrome 6359:Syringofibroadenoma 6256:Epithelioid sarcoma 6221:Granular cell tumor 5855:Nevus unius lateris 5613:Verrucous carcinoma 5229:of Jadassohn–Tièche 5128:Amelanotic melanoma 4759:Sentinel lymph node 4408:"Skin Cancer Facts" 4267:(9859): 2095–2128. 4211:on 3 December 2013. 4064:Skin Cancer Journal 3762:2014PMB....59R.183H 3298:2010IAOEH..83..843K 2920:2018RSCAd...828095N 2914:(49): 28095–28130. 2699:10.1155/2014/409058 1765:10.5826/dpc.0702a01 1325:. 25 October 2013. 1272:(noncancerous) and 1264:Many types of skin 1252:Veterinary medicine 871:Vitamin supplements 808:confocal microscopy 787:signaling pathway. 6914:Metabolic syndrome 6455:Ceruminous adenoma 6450:Hidradenocarcinoma 5603:Mucinous carcinoma 5544:Bowenoid papulosis 5297:Balloon cell nevus 5074:nevi and melanomas 4807:Respiratory system 4574:External resources 4442:Cancer Research UK 4189:10.1007/pl00012378 3915:The New York Times 3635:(5): 1179S–1184S. 3591:10.2147/NSA.S19419 2929:10.1039/c8ra04164d 2844:Atlas of Pathology 2187:Harris RE (2013). 1899:ABC of skin cancer 1446:(Suppl 1): 51–68. 1351:Dunphy LM (2011). 1210: 743: 683:behaviors such as 644:Ionizing radiation 555:. Sometimes small 523:that do not heal, 515:Signs and symptoms 444: 431:Malignant melanoma 425: 406: 373:malignant melanoma 299:. Diagnosis is by 214:5.6 million (2015) 32:For the book, see 7024:Medical mnemonics 7001: 7000: 6988:Teenage pregnancy 6874:Domestic violence 6869:Diabetes mellitus 6705: 6704: 6683: 6682: 6614:Trichofolliculoma 6547:Trichoepithelioma 6520: 6519: 6492:Sebaceous adenoma 6463: 6462: 6392:Dermal cylindroma 6349:Eccrine carcinoma 6272: 6271: 6268: 6267: 6264: 6263: 5898: 5897: 5894: 5893: 5811:Nevus comedonicus 5772: 5771: 5768: 5767: 5694:Warty dyskeratoma 5626: 5625: 5554:Actinic keratosis 5351: 5350: 5347: 5346: 5173:melanocytic nevus 5148:Polypoid melanoma 5036: 5035: 5023:Cancer and nausea 4902: 4901: 4739:Carcinoma in situ 4597: 4596: 4101:(7418): 794–798. 3958:FaceDoctorNYC.com 3854:978-0-7817-5626-6 3822:978-3-540-36718-5 3508:10.1159/000329439 2803:10.1111/php.13245 2622:Arndt KA (2010). 2591:10.1136/bmj.e5909 2522:JAMA Network Open 2200:978-0-7637-8047-0 1997:978-0-387-77573-9 1909:978-1-4443-1250-8 1860:: 131487–131507. 1717:"Defining Cancer" 1402:. 17 April 2014. 1364:978-0-8036-2647-8 1207: 1206: 991:may be required. 919:basal-cell cancer 904:kidney transplant 754:basement membrane 709:pyrimidine dimers 662:immunosuppressive 638:Marjolin's ulcers 607:Light skin color 448: 447: 325:radiation therapy 313:radiation therapy 226: 225: 201:radiation therapy 174:Diagnostic method 41:Medical condition 16:(Redirected from 7031: 6919:Mental disorders 6732: 6725: 6718: 6709: 6637:Fibrofolliculoma 6584:Fibrofolliculoma 6531: 6332: 6323: 6299: 6292: 6285: 6276: 6201:Adenoma sebaceum 6166: 6138:Nevus oligemicus 6111: 6088: 6040: 6022: 6017: 5976: 5925: 5918: 5911: 5902: 5860:Patch blue nevus 5781: 5745:Verruca vulgaris 5637: 5534:Marjolin's ulcer 5522:Signet-ring-cell 5409: 5400: 5378: 5371: 5364: 5355: 5302:Dysplastic nevus 5244:Deep penetrating 5178: 5100:Nodular melanoma 5090:Mucosal melanoma 5063: 5056: 5049: 5040: 4837:Endocrine system 4802:Digestive system 4691: 4664: 4657: 4650: 4641: 4496: 4484: 4483: 4481: 4479: 4464: 4458: 4457: 4455: 4453: 4434: 4428: 4427: 4425: 4423: 4404: 4398: 4397: 4395: 4393: 4384:. Archived from 4374: 4368: 4367: 4362:. Archived from 4352: 4346: 4345: 4343: 4341: 4322: 4313: 4312: 4294: 4284: 4252: 4243: 4242: 4240: 4238: 4219: 4213: 4212: 4207:. Archived from 4168: 4162: 4161: 4156: 4154: 4135: 4129: 4128: 4118: 4086: 4080: 4079: 4077: 4075: 4056: 4050: 4049: 4021: 4015: 4014: 3996: 3972: 3966: 3965: 3964:on 10 July 2011. 3960:. Archived from 3950: 3944: 3943: 3925: 3919: 3918: 3906: 3900: 3899: 3889: 3865: 3859: 3858: 3840: 3834: 3833: 3831: 3829: 3796: 3790: 3789: 3756:(6): R183–R231. 3745: 3739: 3738: 3736: 3734: 3720: 3714: 3713: 3703: 3693: 3661: 3655: 3654: 3644: 3620: 3614: 3613: 3603: 3593: 3569: 3563: 3562: 3534: 3528: 3527: 3490: 3484: 3483: 3473: 3449: 3443: 3442: 3431: 3425: 3424: 3398: 3378: 3369: 3368: 3332: 3326: 3325: 3281: 3275: 3274: 3238: 3232: 3231: 3203: 3197: 3196: 3186: 3169:(12): CD013191. 3154: 3148: 3147: 3137: 3120:(12): CD013188. 3105: 3099: 3098: 3088: 3071:(12): CD013186. 3056: 3050: 3049: 3039: 3022:(12): CD013189. 3007: 3001: 3000: 2990: 2973:(12): CD011901. 2958: 2952: 2951: 2941: 2931: 2899: 2893: 2892: 2890: 2866: 2860: 2859: 2857: 2855: 2836: 2825: 2824: 2814: 2782: 2771: 2770: 2752: 2728: 2722: 2721: 2711: 2701: 2677: 2671: 2670: 2634: 2628: 2627: 2619: 2613: 2612: 2602: 2570: 2564: 2563: 2545: 2513: 2507: 2506: 2478: 2472: 2471: 2443: 2422: 2421: 2403: 2379: 2373: 2372: 2344: 2338: 2337: 2335: 2328: 2320: 2314: 2313: 2311: 2304: 2296: 2290: 2284: 2278: 2277: 2252:(8): 1205–1212. 2243: 2234: 2228: 2227: 2211: 2205: 2204: 2184: 2178: 2177: 2175: 2173: 2154: 2148: 2147: 2119: 2113: 2112: 2110: 2108: 2089: 2083: 2082: 2080: 2078: 2059: 2053: 2052: 2016: 2010: 2009: 1989: 1973: 1967: 1966: 1956: 1939:(3): J247–J257. 1924: 1918: 1917: 1893: 1884: 1883: 1869: 1845: 1839: 1838: 1828: 1818: 1794: 1788: 1787: 1777: 1767: 1743: 1737: 1736: 1734: 1732: 1713: 1707: 1706: 1696: 1686: 1662: 1656: 1655: 1645: 1635: 1611: 1605: 1604: 1594: 1570: 1559: 1558: 1541: 1518: 1517: 1489: 1466: 1465: 1455: 1431: 1416: 1415: 1413: 1411: 1392: 1373: 1372: 1348: 1339: 1338: 1336: 1334: 1315: 1200: 1194: 1188: 1182: 1176: 1170: 1162: 1156: 1150: 1144: 1138: 1132: 1126: 1120: 1111:Age-standardized 860:tobacco products 795:Diagnosis is by 660:The use of many 573:keratoacanthomas 492:Kaposi's sarcoma 378: 329:targeted therapy 56: 44: 21: 7039: 7038: 7034: 7033: 7032: 7030: 7029: 7028: 7004: 7003: 7002: 6997: 6743: 6736: 6706: 6701: 6679: 6651: 6623: 6516: 6477:Nevus sebaceous 6469:Sebaceous gland 6459: 6423: 6373: 6312: 6303: 6273: 6260: 6187: 6162: 6157: 6109: 6104: 6086: 6081: 6038: 6033: 6020: 6008: 5980: 5971: 5965: 5938: 5929: 5899: 5890: 5874: 5840: 5784:Epidermal nevus 5764: 5760:Periungual wart 5731: 5704:Keratoacanthoma 5698: 5674:Melanoacanthoma 5632: 5622: 5581: 5558: 5539:Bowen's disease 5490: 5391: 5382: 5352: 5343: 5310: 5288: 5260: 5215: 5171: 5162: 5153:Nevoid melanoma 5112:Lentigo maligna 5076: 5067: 5037: 5032: 4991: 4944: 4898: 4877: 4841: 4763: 4722: 4682: 4668: 4635:Wayback Machine 4617: 4598: 4593: 4592: 4569: 4568: 4507: 4493: 4488: 4487: 4477: 4475: 4466: 4465: 4461: 4451: 4449: 4436: 4435: 4431: 4421: 4419: 4406: 4405: 4401: 4391: 4389: 4376: 4375: 4371: 4354: 4353: 4349: 4339: 4337: 4324: 4323: 4316: 4254: 4253: 4246: 4236: 4234: 4221: 4220: 4216: 4170: 4169: 4165: 4152: 4150: 4137: 4136: 4132: 4088: 4087: 4083: 4073: 4071: 4058: 4057: 4053: 4023: 4022: 4018: 3974: 3973: 3969: 3952: 3951: 3947: 3927: 3926: 3922: 3908: 3907: 3903: 3867: 3866: 3862: 3855: 3842: 3841: 3837: 3827: 3825: 3823: 3798: 3797: 3793: 3747: 3746: 3742: 3732: 3730: 3722: 3721: 3717: 3676:(4): CD005414. 3663: 3662: 3658: 3622: 3621: 3617: 3571: 3570: 3566: 3536: 3535: 3531: 3492: 3491: 3487: 3451: 3450: 3446: 3433: 3432: 3428: 3396:10.1.1.690.6405 3380: 3379: 3372: 3334: 3333: 3329: 3283: 3282: 3278: 3240: 3239: 3235: 3205: 3204: 3200: 3156: 3155: 3151: 3107: 3106: 3102: 3058: 3057: 3053: 3009: 3008: 3004: 2960: 2959: 2955: 2901: 2900: 2896: 2888:10.15562/tcp.40 2868: 2867: 2863: 2853: 2851: 2838: 2837: 2828: 2784: 2783: 2774: 2730: 2729: 2725: 2679: 2678: 2674: 2636: 2635: 2631: 2621: 2620: 2616: 2572: 2571: 2567: 2515: 2514: 2510: 2480: 2479: 2475: 2445: 2444: 2425: 2381: 2380: 2376: 2346: 2345: 2341: 2333: 2326: 2322: 2321: 2317: 2309: 2302: 2298: 2297: 2293: 2285: 2281: 2241: 2236: 2235: 2231: 2213: 2212: 2208: 2201: 2186: 2185: 2181: 2171: 2169: 2156: 2155: 2151: 2121: 2120: 2116: 2106: 2104: 2091: 2090: 2086: 2076: 2074: 2061: 2060: 2056: 2018: 2017: 2013: 1998: 1975: 1974: 1970: 1926: 1925: 1921: 1910: 1895: 1894: 1887: 1847: 1846: 1842: 1796: 1795: 1791: 1745: 1744: 1740: 1730: 1728: 1715: 1714: 1710: 1664: 1663: 1659: 1613: 1612: 1608: 1572: 1571: 1562: 1555: 1543: 1542: 1521: 1491: 1490: 1469: 1433: 1432: 1419: 1409: 1407: 1394: 1393: 1376: 1365: 1350: 1349: 1342: 1332: 1330: 1317: 1316: 1293: 1288: 1283: 1282: 1262: 1254: 1245: 1226: 1208: 1202: 1198: 1196: 1192: 1190: 1186: 1184: 1180: 1178: 1174: 1172: 1168: 1164: 1160: 1158: 1154: 1152: 1148: 1146: 1142: 1140: 1136: 1134: 1130: 1128: 1124: 1104: 1064: 1039: 1012:BRAF inhibitors 915: 837: 793: 721: 719:Pathophysiology 694: 676:about 60 times. 601: 590: 581: 569: 537: 517: 476:keratoacanthoma 361: 333:palliative care 111: 106: 42: 37: 28: 23: 22: 15: 12: 11: 5: 7037: 7035: 7027: 7026: 7021: 7016: 7006: 7005: 6999: 6998: 6996: 6995: 6990: 6985: 6980: 6975: 6970: 6965: 6960: 6955: 6950: 6945: 6944: 6943: 6933: 6928: 6927: 6926: 6916: 6911: 6906: 6901: 6896: 6891: 6886: 6881: 6876: 6871: 6866: 6861: 6860: 6859: 6849: 6844: 6843: 6842: 6837: 6832: 6827: 6822: 6817: 6812: 6807: 6802: 6797: 6792: 6782: 6777: 6775:Binge drinking 6772: 6767: 6762: 6757: 6751: 6749: 6745: 6744: 6737: 6735: 6734: 6727: 6720: 6712: 6703: 6702: 6700: 6699: 6693: 6691: 6685: 6684: 6681: 6680: 6678: 6677: 6672: 6667: 6661: 6659: 6653: 6652: 6650: 6649: 6644: 6639: 6634: 6628: 6625: 6624: 6622: 6621: 6616: 6611: 6606: 6601: 6596: 6591: 6586: 6581: 6579:Trichoblastoma 6576: 6571: 6570: 6569: 6564: 6559: 6554: 6544: 6534: 6528: 6522: 6521: 6518: 6517: 6515: 6514: 6509: 6504: 6499: 6494: 6489: 6484: 6479: 6473: 6471: 6465: 6464: 6461: 6460: 6458: 6457: 6452: 6443: 6437: 6435: 6425: 6424: 6422: 6421: 6419:Apocrine nevus 6416: 6411: 6406: 6401: 6396: 6395: 6394: 6383: 6381: 6375: 6374: 6372: 6371: 6366: 6361: 6356: 6351: 6346: 6340: 6338: 6329: 6320: 6314: 6313: 6304: 6302: 6301: 6294: 6287: 6279: 6270: 6269: 6266: 6265: 6262: 6261: 6259: 6258: 6253: 6248: 6243: 6238: 6233: 6228: 6223: 6218: 6213: 6208: 6203: 6198: 6192: 6189: 6188: 6186: 6185: 6180: 6175: 6169: 6167: 6159: 6158: 6156: 6155: 6150: 6145: 6140: 6135: 6130: 6125: 6123:Nevus flammeus 6120: 6118:Nevus anemicus 6114: 6112: 6106: 6105: 6103: 6102: 6097: 6091: 6089: 6087:Bone/cartilage 6083: 6082: 6080: 6079: 6074: 6069: 6064: 6059: 6057:Ganglioneuroma 6054: 6049: 6043: 6041: 6035: 6034: 6032: 6031: 6025: 6023: 6014: 6010: 6009: 6007: 6006: 5984: 5982: 5979:Connective and 5973: 5967: 5966: 5964: 5963: 5958: 5948: 5946: 5940: 5939: 5930: 5928: 5927: 5920: 5913: 5905: 5896: 5895: 5892: 5891: 5889: 5888: 5886:Cutaneous horn 5882: 5880: 5876: 5875: 5873: 5872: 5867: 5862: 5857: 5851: 5849: 5842: 5841: 5839: 5838: 5833: 5828: 5823: 5818: 5813: 5808: 5807: 5806: 5801: 5796: 5787: 5785: 5778: 5774: 5773: 5770: 5769: 5766: 5765: 5763: 5762: 5757: 5752: 5747: 5741: 5739: 5733: 5732: 5730: 5729: 5724: 5719: 5714: 5708: 5706: 5700: 5699: 5697: 5696: 5691: 5686: 5681: 5676: 5671: 5670: 5669: 5664: 5659: 5654: 5645: 5643: 5634: 5628: 5627: 5624: 5623: 5621: 5620: 5615: 5610: 5605: 5600: 5595: 5589: 5587: 5583: 5582: 5580: 5579: 5574: 5568: 5566: 5564:Adenocarcinoma 5560: 5559: 5557: 5556: 5551: 5546: 5541: 5536: 5531: 5530: 5529: 5524: 5519: 5514: 5509: 5500: 5498: 5492: 5491: 5489: 5488: 5483: 5482: 5481: 5476: 5471: 5466: 5461: 5456: 5451: 5446: 5441: 5436: 5431: 5426: 5417: 5415: 5406: 5397: 5393: 5392: 5383: 5381: 5380: 5373: 5366: 5358: 5349: 5348: 5345: 5344: 5342: 5341: 5336: 5331: 5326: 5324:Becker's nevus 5321: 5315: 5312: 5311: 5309: 5308: 5299: 5293: 5290: 5289: 5287: 5286: 5280: 5275: 5265: 5262: 5261: 5259: 5258: 5257: 5256: 5251: 5246: 5241: 5236: 5231: 5220: 5217: 5216: 5214: 5213: 5211:Pseudomelanoma 5208: 5203: 5202: 5201: 5191: 5181: 5175: 5164: 5163: 5161: 5160: 5155: 5150: 5145: 5140: 5135: 5130: 5125: 5124: 5123: 5118: 5102: 5097: 5092: 5086: 5084: 5078: 5077: 5068: 5066: 5065: 5058: 5051: 5043: 5034: 5033: 5031: 5030: 5025: 5020: 5015: 5010: 5005: 4999: 4997: 4993: 4992: 4990: 4989: 4984: 4979: 4974: 4965: 4960: 4954: 4952: 4950:Carcinogenesis 4946: 4945: 4943: 4942: 4937: 4932: 4927: 4922: 4916: 4914: 4904: 4903: 4900: 4899: 4897: 4896: 4891: 4885: 4883: 4879: 4878: 4876: 4875: 4870: 4865: 4860: 4855: 4849: 4847: 4843: 4842: 4840: 4839: 4834: 4832:Nervous system 4829: 4824: 4819: 4814: 4809: 4804: 4799: 4798: 4797: 4795:nasopharyngeal 4792: 4787: 4782: 4771: 4769: 4765: 4764: 4762: 4761: 4756: 4751: 4746: 4741: 4736: 4730: 4728: 4724: 4723: 4721: 4720: 4715: 4710: 4705: 4699: 4697: 4688: 4684: 4683: 4669: 4667: 4666: 4659: 4652: 4644: 4638: 4637: 4625: 4601: 4595: 4594: 4591: 4590: 4578: 4577: 4575: 4571: 4570: 4567: 4566: 4555: 4547: 4528: 4508: 4503: 4502: 4500: 4499:Classification 4492: 4491:External links 4489: 4486: 4485: 4459: 4429: 4399: 4388:on 18 May 2014 4369: 4347: 4330:www.cancer.org 4314: 4244: 4214: 4183:(7): 732–735. 4163: 4145:. 3 May 2012. 4130: 4081: 4051: 4016: 3967: 3945: 3920: 3901: 3880:(5): 516–524. 3860: 3853: 3835: 3821: 3791: 3740: 3715: 3656: 3615: 3564: 3545:(6): 644–649. 3529: 3485: 3464:(4): 429–435. 3444: 3426: 3389:(3): 190–201. 3370: 3343:(3): 588–597. 3327: 3292:(8): 843–854. 3276: 3233: 3214:(4): 222–228. 3198: 3149: 3100: 3051: 3002: 2953: 2894: 2881:(5): 1069–80. 2861: 2826: 2797:(3): 478–499. 2772: 2723: 2672: 2629: 2614: 2565: 2528:(3): e223833. 2508: 2489:(3): 160–169. 2473: 2448:Drugs of Today 2423: 2394:(9): 978–986. 2374: 2339: 2315: 2291: 2279: 2229: 2206: 2199: 2179: 2149: 2114: 2084: 2054: 2027:(5): 389–397. 2011: 1996: 1968: 1919: 1908: 1885: 1840: 1789: 1738: 1708: 1657: 1606: 1585:(6): 427–436. 1560: 1554:978-9283204299 1553: 1519: 1500:(4): 419–422. 1467: 1417: 1374: 1363: 1340: 1290: 1289: 1287: 1284: 1263: 1255: 1253: 1250: 1244: 1241: 1225: 1222: 1205: 1204: 1197: 1191: 1185: 1179: 1173: 1167: 1165: 1159: 1153: 1147: 1141: 1135: 1129: 1123: 1118: 1103: 1100: 1063: 1060: 1038: 1037:Reconstruction 1035: 914: 911: 885:titanium oxide 852:indoor tanning 836: 833: 792: 789: 785:Sonic hedgehog 774:keratinization 720: 717: 707:. Cyclobutane 697:UV-irradiation 693: 690: 689: 688: 677: 658: 655: 641: 634: 623: 617: 611: 608: 600: 597: 589: 586: 580: 577: 568: 565: 561:telangiectasia 536: 533: 516: 513: 496:leiomyosarcoma 446: 445: 436: 433: 427: 426: 417: 414: 408: 407: 398: 395: 389: 388: 385: 382: 360: 359:Classification 357: 224: 223: 222:111,700 (2015) 220: 216: 215: 212: 208: 207: 197: 193: 192: 186: 182: 181: 176: 170: 169: 163: 157: 156: 143: 139: 138: 125: 121: 120: 93: 87: 86: 77: 71: 70: 67:telangiectasia 58: 57: 49: 48: 40: 26: 24: 18:Skin neoplasms 14: 13: 10: 9: 6: 4: 3: 2: 7036: 7025: 7022: 7020: 7017: 7015: 7012: 7011: 7009: 6994: 6991: 6989: 6986: 6984: 6981: 6979: 6976: 6974: 6971: 6969: 6966: 6964: 6963:Schizophrenia 6961: 6959: 6956: 6954: 6951: 6949: 6946: 6942: 6939: 6938: 6937: 6934: 6932: 6929: 6925: 6922: 6921: 6920: 6917: 6915: 6912: 6910: 6907: 6905: 6902: 6900: 6897: 6895: 6892: 6890: 6887: 6885: 6882: 6880: 6877: 6875: 6872: 6870: 6867: 6865: 6862: 6858: 6855: 6854: 6853: 6850: 6848: 6845: 6841: 6838: 6836: 6833: 6831: 6828: 6826: 6823: 6821: 6818: 6816: 6813: 6811: 6808: 6806: 6803: 6801: 6798: 6796: 6793: 6791: 6788: 6787: 6786: 6783: 6781: 6778: 6776: 6773: 6771: 6768: 6766: 6763: 6761: 6758: 6756: 6753: 6752: 6750: 6746: 6741: 6733: 6728: 6726: 6721: 6719: 6714: 6713: 6710: 6698: 6695: 6694: 6692: 6690: 6686: 6676: 6673: 6671: 6668: 6666: 6663: 6662: 6660: 6658: 6654: 6648: 6645: 6643: 6640: 6638: 6635: 6633: 6630: 6629: 6626: 6620: 6617: 6615: 6612: 6610: 6609:Trichoadenoma 6607: 6605: 6602: 6600: 6597: 6595: 6592: 6590: 6589:Trichilemmoma 6587: 6585: 6582: 6580: 6577: 6575: 6574:Trichodiscoma 6572: 6568: 6565: 6563: 6560: 6558: 6555: 6553: 6550: 6549: 6548: 6545: 6543: 6539: 6538:Pilomatricoma 6536: 6535: 6532: 6529: 6527: 6523: 6513: 6510: 6508: 6505: 6503: 6500: 6498: 6495: 6493: 6490: 6488: 6485: 6483: 6480: 6478: 6475: 6474: 6472: 6470: 6466: 6456: 6453: 6451: 6447: 6444: 6442: 6439: 6438: 6436: 6434: 6430: 6426: 6420: 6417: 6415: 6412: 6410: 6407: 6405: 6402: 6400: 6397: 6393: 6390: 6389: 6388: 6385: 6384: 6382: 6380: 6376: 6370: 6367: 6365: 6362: 6360: 6357: 6355: 6354:Eccrine nevus 6352: 6350: 6347: 6345: 6342: 6341: 6339: 6337: 6333: 6330: 6328: 6324: 6321: 6319: 6315: 6311: 6307: 6300: 6295: 6293: 6288: 6286: 6281: 6280: 6277: 6257: 6254: 6252: 6249: 6247: 6244: 6242: 6241:Angiokeratoma 6239: 6237: 6236:Neurothekeoma 6234: 6232: 6231:Desmoid tumor 6229: 6227: 6224: 6222: 6219: 6217: 6214: 6212: 6209: 6207: 6204: 6202: 6199: 6197: 6194: 6193: 6190: 6184: 6181: 6179: 6176: 6174: 6171: 6170: 6168: 6165: 6160: 6154: 6151: 6149: 6146: 6144: 6141: 6139: 6136: 6134: 6131: 6129: 6126: 6124: 6121: 6119: 6116: 6115: 6113: 6107: 6101: 6098: 6096: 6093: 6092: 6090: 6084: 6078: 6075: 6073: 6070: 6068: 6065: 6063: 6060: 6058: 6055: 6053: 6050: 6048: 6045: 6044: 6042: 6036: 6030: 6027: 6026: 6024: 6018: 6015: 6011: 6005: 6003: 5999: 5995: 5991: 5986: 5985: 5983: 5977: 5974: 5968: 5962: 5959: 5957: 5953: 5950: 5949: 5947: 5945: 5941: 5937: 5933: 5926: 5921: 5919: 5914: 5912: 5907: 5906: 5903: 5887: 5884: 5883: 5881: 5877: 5871: 5868: 5866: 5863: 5861: 5858: 5856: 5853: 5852: 5850: 5848: 5843: 5837: 5834: 5832: 5829: 5827: 5824: 5822: 5819: 5817: 5814: 5812: 5809: 5805: 5802: 5800: 5797: 5795: 5792: 5791: 5789: 5788: 5786: 5782: 5779: 5775: 5761: 5758: 5756: 5753: 5751: 5750:Verruca plana 5748: 5746: 5743: 5742: 5740: 5738: 5734: 5728: 5725: 5723: 5720: 5718: 5715: 5713: 5710: 5709: 5707: 5705: 5701: 5695: 5692: 5690: 5687: 5685: 5684:Seboacanthoma 5682: 5680: 5677: 5675: 5672: 5668: 5667:Epidermolytic 5665: 5663: 5660: 5658: 5655: 5653: 5650: 5649: 5647: 5646: 5644: 5642: 5638: 5635: 5629: 5619: 5616: 5614: 5611: 5609: 5606: 5604: 5601: 5599: 5596: 5594: 5591: 5590: 5588: 5584: 5578: 5575: 5573: 5570: 5569: 5567: 5565: 5561: 5555: 5552: 5550: 5547: 5545: 5542: 5540: 5537: 5535: 5532: 5528: 5525: 5523: 5520: 5518: 5515: 5513: 5510: 5508: 5505: 5504: 5502: 5501: 5499: 5497: 5493: 5487: 5484: 5480: 5477: 5475: 5472: 5470: 5467: 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4973: 4969: 4966: 4964: 4961: 4959: 4956: 4955: 4953: 4951: 4947: 4941: 4938: 4936: 4933: 4931: 4928: 4926: 4923: 4921: 4918: 4917: 4915: 4913: 4909: 4905: 4895: 4892: 4890: 4887: 4886: 4884: 4880: 4874: 4871: 4869: 4866: 4864: 4861: 4859: 4856: 4854: 4851: 4850: 4848: 4844: 4838: 4835: 4833: 4830: 4828: 4825: 4823: 4820: 4818: 4815: 4813: 4810: 4808: 4805: 4803: 4800: 4796: 4793: 4791: 4788: 4786: 4785:oropharyngeal 4783: 4781: 4778: 4777: 4776: 4775:Head and neck 4773: 4772: 4770: 4766: 4760: 4757: 4755: 4754:Primary tumor 4752: 4750: 4747: 4745: 4742: 4740: 4737: 4735: 4732: 4731: 4729: 4725: 4719: 4716: 4714: 4711: 4709: 4706: 4704: 4701: 4700: 4698: 4696: 4695:Benign tumors 4692: 4689: 4685: 4681: 4677: 4673: 4665: 4660: 4658: 4653: 4651: 4646: 4645: 4642: 4636: 4632: 4629: 4626: 4624: 4620: 4615: 4611: 4610: 4605: 4600: 4599: 4589: 4585: 4584: 4580: 4579: 4576: 4572: 4565: 4561: 4560: 4556: 4553: 4552: 4548: 4546: 4542: 4538: 4537: 4533: 4529: 4527: 4523: 4519: 4518: 4514: 4510: 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1476: 1474: 1472: 1468: 1463: 1459: 1454: 1449: 1445: 1441: 1437: 1430: 1428: 1426: 1424: 1422: 1418: 1405: 1401: 1397: 1391: 1389: 1387: 1385: 1383: 1381: 1379: 1375: 1370: 1366: 1360: 1356: 1355: 1347: 1345: 1341: 1328: 1324: 1320: 1314: 1312: 1310: 1308: 1306: 1304: 1302: 1300: 1298: 1296: 1292: 1285: 1279: 1275: 1271: 1267: 1260: 1251: 1249: 1242: 1240: 1237: 1235: 1230: 1223: 1221: 1219: 1213: 1201: >7.7 1183: 5.6–6.3 1177: 4.9–5.6 1171: 4.2–4.9 1166: 1163: 3.5–4.2 1157: 2.8–3.5 1151: 2.1–2.8 1145: 1.4–2.1 1139: 0.7–1.4 1133: <0.7 1127: no data 1122: 1121: 1116: 1112: 1108: 1101: 1099: 1096: 1092: 1088: 1084: 1080: 1076: 1074: 1068: 1061: 1059: 1055: 1051: 1047: 1043: 1036: 1034: 1030: 1028: 1025: 1024:MEK inhibitor 1021: 1017: 1013: 1009: 1005: 1001: 1000:pembrolizumab 997: 992: 990: 985: 983: 979: 975: 970: 968: 964: 960: 956: 951: 947: 946:brachytherapy 943: 938: 936: 932: 928: 924: 920: 912: 910: 907: 905: 901: 897: 891: 888: 886: 882: 878: 876: 872: 867: 863: 861: 857: 853: 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183: 180: 179:Tissue biopsy 177: 175: 171: 168: 164: 162: 158: 155: 151: 147: 144: 140: 137: 133: 129: 126: 122: 118: 114: 109: 108:Squamous-cell 105: 101: 97: 94: 92: 88: 85: 81: 78: 76: 72: 68: 64: 59: 55: 50: 45: 39: 35: 30: 19: 6993:Tuberculosis 6904:Malnutrition 6748:Health topic 6740:epidemiology 6619:Dilated pore 6409:Hidrocystoma 6216:Glomus tumor 6164:Histiocytoma 6002:mastocytosis 5987: 5970:Subcutaneous 5931: 5755:Plantar wart 5527:Spindle-cell 5474:Rodent ulcer 5449:Micronodular 5444:Infiltrative 5384: 5334:Nevus spilus 5278:Medium-sized 5189:Nevus of Ota 5185:Nevus of Ito 5104: 5069: 4816: 4670:Overview of 4607: 4581: 4557: 4549: 4530: 4511: 4478:28 September 4476:. Retrieved 4462: 4450:. Retrieved 4441: 4432: 4420:. Retrieved 4411: 4402: 4390:. Retrieved 4386:the original 4381: 4372: 4364:the original 4359: 4350: 4338:. Retrieved 4329: 4264: 4260: 4235:. Retrieved 4226: 4217: 4209:the original 4180: 4176: 4166: 4158: 4151:. Retrieved 4142: 4133: 4098: 4094: 4084: 4072:. Retrieved 4063: 4054: 4033: 4029: 4019: 3987:(1): 19–36. 3984: 3980: 3970: 3962:the original 3957: 3948: 3933: 3923: 3914: 3904: 3877: 3873: 3863: 3844: 3838: 3826:. Retrieved 3804: 3794: 3753: 3749: 3743: 3731:. Retrieved 3728:ScienceDaily 3727: 3718: 3673: 3669: 3659: 3632: 3628: 3618: 3581: 3577: 3567: 3542: 3538: 3532: 3502:(1): 36–44. 3499: 3495: 3488: 3461: 3457: 3447: 3438: 3429: 3386: 3382: 3340: 3336: 3330: 3289: 3285: 3279: 3249:(2): 58–67. 3246: 3242: 3236: 3211: 3207: 3201: 3166: 3162: 3152: 3117: 3113: 3103: 3068: 3064: 3054: 3019: 3015: 3005: 2970: 2966: 2956: 2911: 2908:RSC Advances 2907: 2897: 2878: 2874: 2864: 2852:. Retrieved 2843: 2794: 2790: 2740: 2736: 2726: 2689: 2685: 2675: 2642: 2638: 2632: 2623: 2617: 2582: 2578: 2568: 2525: 2521: 2511: 2486: 2482: 2476: 2454:(1): 37–53. 2451: 2447: 2391: 2387: 2377: 2355:(1): 46–53. 2352: 2348: 2342: 2318: 2294: 2282: 2249: 2245: 2232: 2219: 2209: 2189: 2182: 2170:. Retrieved 2161: 2152: 2130:(1): 43–53. 2127: 2123: 2117: 2105:. Retrieved 2096: 2087: 2075:. Retrieved 2066: 2057: 2024: 2020: 2014: 1977: 1971: 1936: 1932: 1922: 1898: 1879: 1857: 1853: 1843: 1806: 1802: 1792: 1755: 1751: 1741: 1729:. Retrieved 1720: 1711: 1674: 1670: 1660: 1623: 1619: 1609: 1582: 1578: 1544: 1497: 1493: 1443: 1439: 1408:. Retrieved 1399: 1353: 1331:. Retrieved 1322: 1246: 1243:Non-melanoma 1238: 1231: 1227: 1214: 1211: 1102:Epidemiology 1077: 1069: 1065: 1056: 1052: 1048: 1044: 1040: 1031: 993: 989:chemotherapy 986: 982:Mohs surgery 974:Mohs surgery 971: 939: 933:or invasive 923:Mohs surgery 916: 908: 892: 889: 879: 868: 864: 849: 838: 827: 822:dermatoscope 819: 815: 812: 805: 794: 778: 766: 762:eosinophilic 747: 744: 695: 674:azathioprine 652:tanning beds 602: 591: 582: 570: 538: 518: 500: 484:angiosarcoma 453: 449: 384:Description 362: 353:South Africa 341: 321:chemotherapy 317:fluorouracil 305: 292:Tanning beds 277: 229:Skin cancers 228: 227: 205:fluorouracil 165:Light skin, 161:Risk factors 154:tanning beds 112: 107: 95: 38: 29: 7019:Sun tanning 6884:Hepatitis D 6879:Hepatitis C 6847:Chikungunya 6364:Spiradenoma 6327:Sweat gland 5932:Skin cancer 5479:Superficial 5429:Cicatricial 5385:Skin cancer 5319:Acral nevus 5283:Small-sized 5239:Epithelioid 5194:Spitz nevus 5070:Skin cancer 5018:Cancer pain 4958:Cancer cell 4703:Hyperplasia 4619:Skin cancer 4602:‹ The 4583:MedlinePlus 4554:: 8010–8720 4237:11 November 3496:Dermatology 3439:Mayo Clinic 2645:(1): 7–11. 1854:IEEE Access 1195: 7–7.7 1189: 6.3–7 1113:death from 1083:New Zealand 1016:vemurafenib 898:, and that 769:keratinized 758:pleomorphic 740:field stain 648:carcinogens 593:Merkel cell 349:New Zealand 288:ozone layer 84:dermatology 47:Skin cancer 7008:Categories 6968:Snakebites 6864:Depression 6810:esophageal 6805:colorectal 6387:Cylindroma 6062:Schwannoma 6021:Urogenital 5790:Syndromes 5662:Clear-cell 5652:Large-cell 5517:Clear-cell 5249:Amelanotic 5224:Blue nevus 5206:Halo nevus 4963:Carcinogen 4827:Urogenital 4768:Topography 4749:Metastasis 4713:Pseudocyst 4687:Conditions 4452:28 October 4153:1 December 3828:15 January 3733:16 January 3691:2123/22258 3584:: 95–112. 3337:Pediatrics 2743:(1): 2–6. 2692:: 409058. 1809:(1): 836. 1803:BMC Cancer 1758:(2): 1–6. 1286:References 1027:trametinib 1020:dabrafenib 1014:, such as 1008:cemiplimab 996:ipilimumab 881:Zinc oxide 835:Prevention 728:Micrograph 482:, such as 259:(SCC) and 185:Prevention 104:ulceration 96:Basal-cell 6953:Pneumonia 6941:childhood 6657:Hamartoma 6512:Mantleoma 6497:Sebaceoma 6441:Syringoma 6226:Carcinoid 5879:Ungrouped 5657:Fissuring 5641:Acanthoma 5586:Ungrouped 5469:Pore-like 5459:Pigmented 5404:Carcinoma 5389:epidermis 5254:Malignant 4982:Oncovirus 4972:oncogenes 4925:Ann Arbor 4868:Papilloma 4853:Carcinoma 4846:Histology 4790:laryngeal 4734:Dysplasia 4718:Hamartoma 4470:. WebMD. 4340:9 January 3935:eMedicine 3391:CiteSeerX 2585:: e5909. 2560:247616874 1876:2169-3536 1274:malignant 1079:Australia 1062:Prognosis 1004:nivolumab 950:imiquimod 913:Treatment 900:acitretin 856:sunscreen 840:Sunscreen 825:methods. 791:Diagnosis 750:fungating 553:shoulders 345:Australia 308:sunscreen 282:from the 211:Frequency 199:Surgery, 196:Treatment 190:sunscreen 148:from the 75:Specialty 6983:Syphilis 6894:HIV/AIDS 6852:Dementia 6825:prostate 6820:lymphoma 6800:cervical 6770:Bed bugs 6433:apocrine 6379:Apocrine 6196:Teratoma 6095:Chordoma 5981:vascular 5727:Solitary 5722:Multiple 5512:Basaloid 5464:Polypoid 5424:Aberrant 5234:Cellular 5082:Melanoma 5003:Research 4863:Blastoma 4680:oncology 4631:Archived 4604:template 4472:Archived 4446:Archived 4416:Archived 4334:Archived 4301:23245604 4292:10790329 4231:Archived 4229:. 2009. 4205:11995057 4197:10390596 4147:Archived 4125:14525881 4068:Archived 4066:. 2009. 4046:Archived 4042:10929700 4011:40987916 3940:Archived 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